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Magnetic bimetallic nanoparticles find many industrial and clinical applications in the field of water treatment, antibacterial and anticancer activities. Therefore, the current article reports green synthesis using oleo-polyol as a surface modifier and synthesis agent for bimetallic magnetic magnesium ferrite nanoparticles. The role of hydroxyl functionality of castor oil (a natural polyol) on the enhancement of structural, morphological, magnetic, and particle size properties has also been discussed. These properties were characterized using FTIR, XRD spectroscopy, SEM, AFM, and TEM microscopy, Brunauer-Emmett-Teller (BET), and vibrating sample magnetometer (VSM) techniques. The effect of calcination temperatures (600-900 °C) on particle size (23-40 nm to 500-600 nm), crystallite sizes (73.15-292.67 nm), and saturation magnetization (20.87, 23.07, 32.39, and 33.13 emu g

Lung cancer is the leading cause of cancer deaths globally; 1 in 16 people are diagnosed with lung cancer in their lifetime. Microtubules, a critical cytoskeletal assembly, have an essential role in cell division. Interference with the microtubule assembly leads to genetic instability during mitosis and cancer cell death. Currently, available antimitotic drugs such as vincas and taxanes are limited due to side effects such as alopecia, myelosuppression, and drug resistance. Noscapine, an opium alkaloid, is a tubulin-binding agent and can alter the microtubule assembly, causing cancer cell death. Amino acids are fundamental building blocks for protein synthesis, making them essential for the biosynthesis of cancer cells. However, the ability of amino acids in drug transportation has yet to be exploited in developing noscapine analogues as a potential drug candidate for cancer. Hence, in the present study, we have explored the ninth position of noscapine by introducing a hydroxymethylene group using the Blanc reaction and further coupled it with a series of amino acids to construct five target conjugates in good yields. The synthesized amino acid conjugate molecules were biologically evaluated against the A549 lung cancer cell line, among which the noscapine-tryptophan conjugate showed IC

This study reports the synthesis of copper–zinc binary oxide coupled cadmium tungstate through a simple bio-precipitation method followed by calcination at 600 °C and its adsorption application. The characterization analysis reveals that the prepared composite has low particles size (nano-range), high porosity, and functional groups on the surface. The calcination of sample at 600 °C causes some essential function groups to disappear on the surface. Prepared composite was found to be effective adsorptive material to treat Congo red dye in aqueous solution. 2.5 g L−1 dose of adsorbent could remove more than 99% Congo red dye from 10 mg L−1 solution and more than 80% Congo red dye from 60 mg L−1 aqueous solution. The maximum adsorption capacity of present adsorbent was calculated to be 19.6 mg Congo red per gram of adsorbent. Isotherms analysis suggested a physio-chemical adsorption process. Thermodynamic analysis revealed a exothermic and feasible adsorption process. Adsorption rate was well explained by pseudo second order kinetics. The rate determining step was intra-particle diffusion evaluated from the Weber-Morris plot. To assess the adsorption performance of present adsorbent for Congo red dye the partition coefficient and adsorption equilibrium capacity were compared with other adsorbents. The partition coefficient and adsorption equilibrium values for 10 mg L−1 aqueous solution were found to be approximately 83.3 mg g−1 µM−1 and 4.0 mg g−1 at 30 °C and 7.0 pH using 2.5 g L−1 adsorbent. The value of partition coefficient was found to be higher than previous reported zinc oxide coupled cadmium tungstate having partition coefficient = as 21.4 mg g−1 µM−1 at 30 °C and 7.0 pH using 2.0 g L−1 adsorbent (Fatima, B., Siddiqui, S.I., Nirala, R.K. et al., Environ. Poll. 2021, 271, 116401). These results suggested that present adsorption technology is efficient for wastewater treatment.

Surface functionalized tri-metallic strontium magnesium ferrite (Sr0.3Mg0.7Fe2O4, SMF) nanoparticles were synthesized by using facile solvent less green oleo polyol method. Various analytical techniques (XRD, XPS, FT-IR, TEM, SEM, BET, and VSM) were used for the investigation of the crystal lattice, surface functionalization, morphology, surface area, and magnetic properties of these nanoparticles. SEM and TEM analysis revealed that the nanoparticles exhibit mesoporous morphology with cubic structure. These mesoporous nanoparticles have been exploited for the removal of toxic organic pollutant (Congo red, CR) from the aqueous solution. Detailed investigations on the adsorption of CR dye by these nanoparticles have been conducted via the rate kinetics study using various adsorption isotherms (Freundlich, Langmuir, Temkin, etc.). These studies revealed that the mesoporous SMF nanoparticles with the high surface area (21.85 m2g−1), have exhibited superior adsorption capacity (>90% within 30 min) and fast separation ability under the influence of external magnetic field along with good recyclability (∼93%). The adsorption analysis of magnetic SMF revealed pseudo-second order dye removal kinetics and follow Freundlich isotherms. These properties of magnetic SMF nanocubes provide an extra edge over other such reported systems and may find its potential as a cost-effective magnetic adsorbent for water treatment application.

Hydrogel is a linkage of 3D chains which are insoluble in water, hydrophilic, and occasionally can be observed as colloidal gel. Hydrogels are natural or synthetic and highly absorbent cross-linked polymers that absorb considerable amounts of aqueous solutions and can contain over 99.9% of water. The network is composed of homopolymers or copolymers and is insoluble due to the presence of chemical or physical cross-links such as entanglements or crystallites. These hydrogels possess a thermodynamic compatibility with water which allows them to swell in aqueous media. Entrapment of microbial cells within hydrogel beads has the advantage of low toxicity. Environmentally sensitive hydrogels have the ability to sense changes of pH, temperature, or the concentration of metabolite and release their load as a result of such a change. Hydrogels are biocompatible, further, and can be used in biomedical fields such as drug delivery, wound healing, and tissue engineering.

In 21st century, providing the fresh and affordable water through protects and purifying the water source from pollutants is biggest and most concern environmental challenges. Toxic element particularly arsenic in water is serious matter of threat for human from many developing countries, and long exposure of arsenic is generally associated with skin lesions and hyperkeratosis like adverse effects. Graphene oxide (GO) and its composites have attracted widespread attentions as novel adsorbents for the adsorption of various water pollutants due to their unique physicochemical characteristics. This chapter presents advances made in the synthesis of graphene oxides and their composites, and summarizes the application of these materials as a superior adsorbent for the removal of arsenic from water. The adsorption affinity in terms of contact time, pH, and temperature has been discussed. Competitive ion effect and regeneration are included within the text. Moreover, the challenges for the commercial uses are discussed.