13 results on '"Rana Gunoz Comert"'
Search Results
2. Encapsulated Papillary Carcinoma in A Man with Gynecomastia: Ultrasonography, Mammography and Magnetic Resonance Imaging Features with Pathologic Correlation
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Ravza Yılmaz, Rana Günöz Cömert, Samil Aliyev, Yücel Toktaş, Semen Önder, Selman Emirikçi, and Vahit Özmen
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encapsulated papillary carcinoma ,intracystic papillary carcinoma ,male ,gynecomastia ,magnetic resonance imaging ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 ,Medicine - Abstract
Male breast cancer is an uncommon disease that constitutes 1% of all breast cancers and encapsulated papillary carcinoma (EPC) is a rare subtype of malignant male diseases. Gynecomastia is the most common disease of the male breast. We report a 63-year-old male patient with EPC accompanied by gynecomastia that was diagnosed and treated at our breast center. Mammography showed an oval-shaped dense mass with circumscribed margins on the ground of nodular gynecomastia. On ultrasonographic exam, we saw a well-circumscribed complex mass with a solid component which was vascular on Doppler ultrasonography. Magnetic resonance imaging revealed a complex cystic mass containing solid components. Dynamic images showed enhancement of the cystic mass wall and mural components. Tumor stage was evaluated as T2N0. The lesion’s histologic examination and immunohistochemical analysis by showing no myoepithelial layer revealed an encapsulated papillary carcinoma. To our knowledge, this is the first case report which describes MR imaging findings of male breast encapsulated papillary cancer.
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- 2018
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3. Axillary lymph node dissection is not required for breast cancer patients with minimal axillary residual disease after neoadjuvant chemotherapy
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Mahmut Muslumanoglu, Baran Mollavelioglu, Neslihan Cabioglu, Selman Emiroglu, Mustafa Tukenmez, Hasan Karanlık, Tolga Ozmen, Ravza Yılmaz, Rana Gunoz Comert, Semen Onder, Aysel Bayram, Duygu Has Simsek, Melis Oflas, Kamuran Ibis, Adnan Aydıner, Vahit Ozmen, and Abdullah Igci
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Breast Cancer ,Breast surgery ,Neoadjuvant chemotherapy ,Axillary lymph node dissection ,Sentinel lymph node biopsy ,Surgery ,RD1-811 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Sentinel lymph node biopsy (SLNB) is widely used in patients who receive neoadjuvant chemotherapy (NAC). Still, axillary lymph node dissection (ALND) is recommended for patients with any axillary residual disease after NAC. The necessity of ALND in patients with minimal axillary disease is unclear. We aim to investigate regional recurrence rates in patients with limited axillary residual disease after NAC underwent SLNB + image-tailored axillary surgery and adjuvant radiotherapy (RT). Methods Patients with clinical stages were T1-3 and N1 at the time of diagnosis, clinically good or complete axillary response after NAC, and limited axillary residue (≤ 3 pathological lymph nodes) with favorable response to NAC in the final pathological examination were included in the study. All patients underwent SLNB + image-tailored axillary surgery. Peripheral lymphatic radiotherapy was applied, and no further surgery was performed in patients with compatible radiology and pathology results. Results Our study, which evaluated 139 patients with a median age of 47 years, found that the median number of excised lymph nodes was 4. Notably, 46% of patients had between 1 and 3 lymph nodes excised, while 45% had between 4 and 6. Only 9% of patients had ≥ 7 lymph nodes. 83(60%) of the patients underwent breast-conserving surgery (BCS), and 56(40%) underwent mastectomy. The study’s median follow-up period was 44 months. During this duration, one breast recurrence (0.7%), one supraclavicular recurrence (0.7%), and six systemic recurrences (4.3%) were observed. No axillary recurrence occurred within the follow-up period. Conclusions Patients presenting with pathological-suspicious ≤ 3 lymph nodes on imaging and showing a good response to NAC can be considered suitable candidates for SLNB + image-tailored axillary surgery, followed by adjuvant RT instead of ALND.
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- 2024
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4. Trichobezoar presenting as an acute abdominal obstruction in a 17-year-old girl
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Zuhal Bayramoglu, Rana Gunoz Comert, Basak Erginel, and Abdulkadir Baziki
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Bezoars ,Radiography, Abdominal ,Laparotomy ,Adolescent ,Stomach ,Pediatrics, Perinatology and Child Health ,Humans ,Female ,Intestinal Obstruction - Abstract
Trichobezoars are hairballs that combine with food residue in the digestive tract as a result of ingesting hair. A 17-year-old girl was admitted to the emergency department with abdominal pain and vomiting for 3 days. She had been having digestive difficulty and bloating for the previous 2 months. An abdominal radiograph demonstrated air-fluid levels consistent with ileus, and an ultrasound showed hyperechoic material in the stomach and ileum. Computed tomography demonstrated images of trapped air which was considered diagnostic of a bezoar. At laparotomy, a large mass was removed from the stomach. As the bezoar extended through the pylorus and duodenum and there were mobile masses palpable in the ileum, it required a second incision to remove them. For some years she had had a habit of swallowing hair which she found on her pillow and there was a history of an obsessive personality trait and hyperactivity for which she agreed to attend a psychiatric clinic.
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- 2022
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5. Correlation of laboratory parameters and Chest CT findings in young adults with COVID-19 and comparison of imaging findings with children
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Selda Hançerli Törün, Rana Gunoz Comert, Nilufar Gasimli, Sukru Mehmet Erturk, Mehpare Sarı Yanartaş, Eda Cingoz, Özge Kaba, Atadan Tunaci, Ayper Somer, and Zuhal Bayramoglu
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Adult ,Male ,Pediatrics ,medicine.medical_specialty ,Adolescent ,Coronavirus disease 2019 (COVID-19) ,Chest ct ,030218 nuclear medicine & medical imaging ,Correlation ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Young adult ,Child ,Pediatric Radiology ,Computed tomography ,Children ,Lung ,Halo sign ,Retrospective Studies ,SARS-CoV-2 ,business.industry ,Infant, Newborn ,COVID-19 ,Infant ,Retrospective cohort study ,Exact test ,Child, Preschool ,030220 oncology & carcinogenesis ,Radiological weapon ,Female ,medicine.symptom ,Laboratories ,Tomography, X-Ray Computed ,business ,Young adults - Abstract
Purpose We aimed to compare COVID-19 imaging findings of young adults (19–35 years of age) with those of children (0–18 years) and to correlate imaging findings of young adults with their laboratory tests. Materials and methods This retrospective study included Real Time-Polymerase Chain Reaction (RT-PCR) confirmed 130 young adults (mean age: 28.39 ± 4.77; 65 male, 65 female) and 36 children (mean age: 12.41 ± 4.51; 17 male, 19 female), between March and June 2020. COVID-19 related imaging findings on chest CT were examined in young adults and compared with children by the Mann-Whitney U, and Chi-square or Fisher's exact test. Laboratory examinations of young adults were assessed in terms of correlation with radiological findings by the Spearman's correlation analysis. Results Bilateral multiple distributions (p = 0.014), subpleural involvement, and pleural thickening (p = 0.004), GGOs with internal consolidations were more frequent in adults (p = 0.009). Infiltrations were significantly larger than 20 mm in young adults (p = 0.011). The rates of feeding vessel sign, vascular enlargement, and halo sign were significantly higher in young adults (p
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- 2021
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6. Covid-19: Correlation of Early Chest Computed Tomography Findings With the Course of Disease
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Alpay Medetalibeyoglu, Gorkem Durak, Emre Uysal, Atadan Tunaci, Rana Gunoz Comert, Naci Senkal, Hakan Ayyildiz, and Sukru Mehmet Erturk
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Adult ,Male ,medicine.medical_specialty ,Radiography ,Pneumonia, Viral ,Air trapping ,030218 nuclear medicine & medical imaging ,law.invention ,Betacoronavirus ,Young Adult ,03 medical and health sciences ,symbols.namesake ,0302 clinical medicine ,law ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Lung ,Pandemics ,Fisher's exact test ,Aged ,Retrospective Studies ,Aged, 80 and over ,Bronchus ,SARS-CoV-2 ,business.industry ,COVID-19 ,Retrospective cohort study ,Middle Aged ,medicine.disease ,Intensive care unit ,Pneumonia ,medicine.anatomical_structure ,Radiology Nuclear Medicine and imaging ,Disease Progression ,symbols ,Female ,Radiography, Thoracic ,Radiology ,medicine.symptom ,Coronavirus Infections ,Tomography, X-Ray Computed ,business ,030217 neurology & neurosurgery - Abstract
OBJECTIVE: To investigate the role of chest computed tomography (CT) examinations acquired early after initial onset of symptoms in predicting disease course in coronavirus disease 2019. METHODS: Two hundred sixty-two patients were categorized according to intensive care unit (ICU) admission, survival, length of hospital stay, and reverse transcriptase-polymerase chain reaction positivity. Mean time interval between the onset of symptoms and CT scan was 5.2 ± 2.3 days. Groups were compared using Student t test, Mann-Whitney U, and Fisher exact tests. RESULTS: In the ICU (+) and died groups, crazy paving (64% and 57.1%), bronchus distortion (68% and 66.7%), bronchiectasis-bronchiolectasis (80% and 76.2%), air trapping (52% and 52.4%) and mediastinal-hilar lymph node enlargement (52% and 52.4%) were significantly more encountered (P < 0,05). These findings were correlated with longer hospital stays (P < 0.05). There were no differences between reverse transcriptase-polymerase chain reaction-positive and -negative patients except bronchiectasis-bronchiolectasis. CONCLUSION: Computed tomography examinations performed early after the onset of symptoms may help in predicting disease course and planning of resources, such as ICU beds.
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- 2020
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7. Pancreatic MR Imaging and Endocrine Complications in Patients with Beta Thalassemia: A Single Center Experience
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Cihangir Sevimli, Yasin Yilmaz, Zuhal Bayramoglu, Rana Gunoz Comert, Nurdan Gul, Memduh Dursun, and Zeynep Karakas
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Iron deposition in various organs can cause endocrine complications in patients with transfusion-dependent beta-thalassemia. The aim was to investigate the relationship between endocrine complications and pancreatic iron overload using magnetic resonance imaging (MRI). Forty patients with transfusion-dependent thalassemia (TDT) were enrolled in the study. The magnetic resonance imagings of the patients were performed using a 1.5 Tesla Philips MRI scanner. Two out of three patients had at least one clinical endocrine complication. The rate of iron deposition was 62.5% in liver, and 45% in pancreas tissue, and was 12.5% in heart tissue. Pancreatic T2* and hepatic T2* values were significantly positively correlated (p = 0.006). Pancreatic T2* and ferritin were significantly negatively correlated (p = 0.03). Cardiac T2* values were negatively correlated with fasting blood glucose (p = 0.03). Patients with short stature had significantly higher cardiac iron burden (22.3 vs. 36.6 T2*ms; p00.01) and patients with hypothyroidism had higher liver iron concentrations (9.9 vs. 6.4 LIC mg/g; p = 0.05). The ferritin level of 841 ng/mL, and liver iron concentration (LIC) value of 8.7 mg/g were detected as the threshold level for severe pancreatic iron burden (AUC 70%, p:0.04, AUC 80%, p = 0.002, respectively). Moreover, males were found to have decreased pancreas T2* values compared with the values in females (T2* 19.3 vs. 29.9, p = 0.05). Patients with higher ferritin levels over than 840 ng/mL should be closely monitored for pancreatic iron deposition, and patients with endocrine complications should be assessed in terms of cardiac iron burden.
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- 2021
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8. Imaging Features of Pediatric COVID-19 on Chest Radiography and Chest CT: A Retrospective, Single-Center Study
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Eda Canıpek, Özge Kaba, Mehpare Sarı Yanartaş, Nilufar Gasimli, Selda Hançerli Törün, Zuhal Bayramoglu, Rana Gunoz Comert, Ayper Somer, and Sukru Mehmet Erturk
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Male ,Coronavirus disease 2019 (COVID-19) ,Adolescent ,RT-PCR, reverse transcription-polymerase chain reaction ,Radiography ,Pneumonia, Viral ,PBT, peribronchial thickening ,Single Center ,SARS-CoV-2, severe acute respiratory syndrome coronavirus 2 ,Betacoronavirus ,Interquartile range ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,RLL, right lower lobe ,Child ,Halo sign ,Children ,Lung ,Pandemics ,IQR, interquartile range ,Original Investigation ,Retrospective Studies ,RUL, right upper lobe ,COVID-19, Coronavirus disease 2019 ,business.industry ,SARS-CoV-2 ,LUL, left upper lobe ,COVID-19 ,Retrospective cohort study ,CT, computed tomography ,medicine.anatomical_structure ,GGO, ground-glass opacity ,El Niño ,Radiology Nuclear Medicine and imaging ,Female ,Radiography, Thoracic ,medicine.symptom ,LLL, left lower lobe ,Nuclear medicine ,business ,Coronavirus Infections ,Tomography, X-Ray Computed ,RML, right middle lobe ,CT - Abstract
Rationale and Objectives This study aims to reveal the imaging features of Coronavirus Disease 2019 (COVID-19) in children. Materials and Methods Sixty-nine chest radiographs and 37 chest CT examinations of 74 children (36 male; median (interquartile range) age:11 (6.25–15) years, 38 female; median (interquartile range) age: 12 (5.75–16) years) with positive real-time reverse transcription-polymerase chain reaction results between March 10 and May 31, 2020, were evaluated in this retrospective study. Differences in 0– 0.05). The rate of ground-glass opacities with or without consolidation (17/37, 45.94%) was higher than consolidation alone (6/37, 16.2%). Feeding vessel sign (16/37, 43.2%), halo sign (9/37, 24.3%), pleural thickening (6/37, 16.2%), interlobular interstitial thickening (5/37, 13.5%), and lymphadenopathy (3/37, 8.1%) were other imaging findings. Conclusion Unilateral or bilateral distributed ground-glass opacities often associated with feeding vessel sign, halo sign, and pleural thickening on chest CT without significant differences between age groups were findings of COVID-19 in children.
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- 2020
9. Encapsulated Papillary Carcinoma in A Man with Gynecomastia: Ultrasonography, Mammography and Magnetic Resonance Imaging Features with Pathologic Correlation
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Samil Aliyev, Yücel Toktaş, Selman Emirikçi, Semen Onder, Vahit Ozmen, Ravza Yilmaz, and Rana Gunoz Comert
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medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Myoepithelial cell ,Cancer ,Magnetic resonance imaging ,Case Report ,medicine.disease ,030218 nuclear medicine & medical imaging ,Lesion ,03 medical and health sciences ,0302 clinical medicine ,Gynecomastia ,030220 oncology & carcinogenesis ,Male breast cancer ,medicine ,Immunohistochemistry ,Mammography ,Radiology ,medicine.symptom ,business ,skin and connective tissue diseases - Abstract
Male breast cancer is an uncommon disease that constitutes 1% of all breast cancers and encapsulated papillary carcinoma (EPC) is a rare subtype of malignant male diseases. Gynecomastia is the most common disease of the male breast. We report a 63-year-old male patient with EPC accompanied by gynecomastia that was diagnosed and treated at our breast center. Mammography showed an oval-shaped dense mass with circumscribed margins on the ground of nodular gynecomastia. On ultrasonographic exam, we saw a well-circumscribed complex mass with a solid component which was vascular on Doppler ultrasonography. Magnetic resonance imaging revealed a complex cystic mass containing solid components. Dynamic images showed enhancement of the cystic mass wall and mural components. Tumor stage was evaluated as T2N0. The lesion's histologic examination and immunohistochemical analysis by showing no myoepithelial layer revealed an encapsulated papillary carcinoma. To our knowledge, this is the first case report which describes MR imaging findings of male breast encapsulated papillary cancer.
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- 2018
10. Evaluation of parotid glands in healthy children and adolescents using shear wave elastography and superb microvascular imaging
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Emine Caliskan, Ibrahim Adaletli, Zuhal Bayramoglu, Rana Gunoz Comert, and Mehmet Öztürk
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Male ,Adolescent ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Power doppler ,0302 clinical medicine ,Vascularity ,Reference Values ,mental disorders ,Medicine ,Humans ,Parotid Gland ,Radiology, Nuclear Medicine and imaging ,Prospective cohort study ,Child ,Neuroradiology ,Shear wave elastography ,business.industry ,Microcirculation ,Ultrasound ,Ultrasonography, Doppler ,General Medicine ,Parotid gland ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Child, Preschool ,Elasticity Imaging Techniques ,Female ,medicine.symptom ,business ,Nuclear medicine ,Body mass index - Abstract
We aim to determine parotid gland elasticity values from healthy children and adolescents using shear wave elastography (SWE). We also define the degree of vascularity using superb microvascular imaging (SMI), power Doppler (PD), and color Doppler (CD) and compare SMI with CD and PD. A total of 100 cases, comprising 50 girls and 50 boys, with ages ranging from 3 to 17 years were included in this prospective study. SWE, SMI, PD, and CD measurements were taken from both parotid glands, and the relationships with sex, age, and body mass index (BMI) were determined. The SMI was compared with the PD and CD. The median elasticity values measured with SWE were 8.37 ± 2.09 kPa and 1.68 ± 0.26 m/s on the right and 8.33 ± 2.04 kPa and 1.69 ± 0.26 m/s on the left. There were significant positive correlations present for those aged below and above 10 years and for BMI with elasticity values. The median vascular spot numbers measured using SMI, PD, and CD were 5 ± 1.70, 3.5 ± 1.45, and 2 ± 1.1 on the right and 4 ± 1.7, 4 ± 1.43, and 2 ± 1.05 on the left, respectively. The median values obtained with SMI were significantly higher than the median values obtained with both PD and CD. This study determined the reference SWE, SMI, PD, and CD values for normal parotid glands in healthy children and adolescents. Elasticity values were affected by age and BMI. There was no correlation between vascularity values and age, sex, or BMI. SMI provided more detailed information about vascularity compared with the other methods.
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- 2017
11. Shear wave elastography evaluation in pediatric testicular microlithiasis: a comparative study
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Tayfun Oktar, Ravza Yilmaz, Sedat Giray Kandemirli, Emine Caliskan, Ibrahim Adaletli, Rana Gunoz Comert, Yunus Emre Akpinar, Bilal Çetin, Mehmet Cingoz, and Zuhal Bayramoglu
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Male ,medicine.medical_specialty ,Testicular tissue ,Adolescent ,030232 urology & nephrology ,Testicular Diseases ,Calculi ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Testis ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Child ,Normal control ,Shear wave elastography ,business.industry ,Ultrasound ,Testicular Parenchyma ,General Medicine ,medicine.disease ,Child, Preschool ,Elasticity Imaging Techniques ,Radiology ,business ,Nuclear medicine ,Testicular microlithiasis - Abstract
Purpose The aim of this study was to evaluate the testicular parenchyma in pediatric patients with testicular microlithiasis by shear wave elastography (SWE) and compare the values with normal control subjects. Methods Twenty-three patients previously diagnosed with testicular microlithiasis under follow-up for 20 ± 11 months were included in the study group. In the control group, 31 patients with no medical history that could affect testicular tissue were prospectively included. Forty-six testes in the study group and 62 testes in the control group were evaluated with gray-scale ultrasound and SWE. Results There were no differences in age and testes volume between the study and control groups. The mean SWE values of all testes based on elasticity and speed parameters in the study group were 8.84 ± 2.86 kPa and 1.66 ± 0.26 m/s, respectively. In the control group, mean SWE values were 5.26 ± 1.17 kPa and 1.31 ± 0.14 m/s, respectively. Elasticity values were significantly higher in testes with microlithiasis as compared with the control group (p Conclusions SWE evaluation demonstrates the effects of ultrastructural changes in elasticity that are not detected on gray-scale ultrasound. SWE is a more reliable method in follow-up examinations for pediatric testicular microlithiasis.
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- 2017
12. Relation of Pancreatic Iron Overload Detected By MRI with Disorders of Glucose Metabolism and Results of Liver, Cardiac and Pitutiary MRI Among Transfusion Dependent Thalassemia (TDT) Patients in Turkey
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Nurdan Gul, Cihangir Sevimli, Memduh Dursun, Zeynep Karakas, and Rana Gunoz Comert
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medicine.medical_specialty ,Thalassemia ,Immunology ,Biochemistry ,Gastroenterology ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Glucose Metabolism Disorder ,Internal medicine ,Diabetes mellitus ,medicine ,medicine.diagnostic_test ,biology ,business.industry ,Magnetic resonance imaging ,Cell Biology ,Hematology ,medicine.disease ,Ferritin ,Fructosamine ,medicine.anatomical_structure ,chemistry ,030220 oncology & carcinogenesis ,biology.protein ,Siderosis ,Pancreas ,business - Abstract
The relationship between pancreatic iron overload and glucose dysregulation has not been well defined and need further investigation. Pancreas iron load measurements are also necessary to understand how hepatic, pancreatic, and cardiac iron burden prospectively modulate the evolution of diabetes in transfusion dependent thalassemia (TDT). Aim: This study aims to evaluate the presence of pancreatic iron overload among TDT patients in Turkey based on the MRI R2* and T2* results as well as to determine its association to Fasting blood glucose (FBG), insulin, fructosamine, Homa-IR, C-peptide, ferritin, liver, cardiac and hypophysis MRI R2* results. Material and Methods: This study was conducted at the Thalassemia Center in Istanbul University, Istanbul Medical Faculty. Forty-one TDT patients included the study with a mean age of 29.9±9,9 (median 29) years old, ranging from 11 to 45 years old. Pancreatic, liver, cardiac and hypophsis MRI's were conducted using 1.5 Tesla Philips MRI machine in the Department of Radiology. Pancreatic MRI R2* results < 30 Hz were considered normal, 30-100 Hz as mild, and > 100 Hz as moderate to severe pancreatic siderosis. Pancreatic MRI T2 results >26 ms were is normal, < 10 ms is severe iron overload as presented at literature. Correlations between pancreatic MRI R2* results and FBG, insulin, fructosamine, Homa-IR, C-peptide, ferritin, cardiac and hypophysis MRI R2* were evaluated using the Pearson correlation, Man Whitney U test. Results: Laboratory findings of glucose metabolism and MRI's of liver, pancreas, hypophsis and cardiac iron are shown at Table 1. There were no significant relationship between fasting blood glucose, insülin, C-peptid level, fructosamine, Homa-IR, ferritin and Pancreas T2* and R2* results (p>0.05). There was significant correlation between liver and pancreas MRI T2* and R2* results. (p0.05). Fourteen patients were found to have normal pancreatic MRI R2* (34,1%) while 19 patients have normal pancreatic MRI T2 (46.3%). It is reported that T2 is irrelevant to age and sex, and R2 can be related to age-related fatty degeneration. There was significant pancreatic iron burden in 31.7% of patients (R2*>100 Hz), of whom only 1 patient was under 18 years of age.There were 22 (53.6%) patients with T2* Discussion:The lack of correlation between pancreatic and cardiac MRI R2* are in contrast to another demonstrating that pancreatic iron load are good predictors of cardiac iron load. This is due to the fact that our patients are followed up with cardiac MR and taken to the intensive chelation programs of the patients who detect iron in the heart. Previous studies also report that while pancreatic R2* may be sensitive for glucose dysregulation, most patients may still have no symptoms and normal blood glucose, indicating the presence of a preclinical iron burden. Pancreatic MRI R2* can detect pancreatic iron accumulation at a much earlier stage. Lack of excessive iron load in liver of our patient can be explain low glucose metabolism disorder despite high pancreatic iron overload. Disclosures No relevant conflicts of interest to declare.
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- 2018
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13. Radiological Findings in SARS-CoV-2 Viral Pneumonia Compared to Other Viral Pneumonias: A Single-Centre Study
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Rana Günöz Cömert, Eda Cingöz, Sevim Meşe, Görkem Durak, Atadan Tunaci, Ali Ağaçfidan, Mustafa Önel, and Şükrü Mehmet Ertürk
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Infectious and parasitic diseases ,RC109-216 ,Microbiology ,QR1-502 - Abstract
Background. Thorax computed tomography (CT) imaging is widely used as a diagnostic method in the diagnosis of coronavirus disease 2019 (COVID-19)-related pneumonia. Radiological differential diagnosis and isolation of other viral agents causing pneumonia in patients have gained importance, particularly during the pandemic. Aims. We aimed to investigate whether there is a difference between CT images from patients with COVID-19-associated pneumonia compared to CT images of patients with pneumonia due to other viral agents and which finding may be more effective in diagnosis. Study Design. The study included 249 adult patients with pneumonia identified by thorax CT examination and with a positive COVID-19 RT-PCR test compared to 94 patients diagnosed with non-COVID-19 pneumonia (viral PCR positive but no bacterial or fungal agents detected in other cultures) between 2015 and 2019. CT images were retrospectively analyzed using the PACS system. CT findings were evaluated by two radiologists with 5 and 20 years of experience, in a blinded fashion, and the outcome was decided by consensus. Methods. Demographic data (age, gender, and known chronic disease) and CT imaging findings (percentage of involvement, number of lesions, distribution preference, dominant pattern, ground-glass opacity distribution pattern, nodule, tree in bud sign, interstitial changes, crazy paving sign, reversed halo sign, vacuolar sign, halo sign, vascular enlargement, linear opacities, traction bronchiectasis, peribronchial wall thickness, air trapping, pleural retraction, pleural effusion, pericardial effusion, cavitation, mediastinal/hilar lymphadenopathy, dominant lesion size, consolidation, subpleural curvilinear opacities, air bronchogram, and pleural thickening) of the patients were evaluated. CT findings were also evaluated with the RSNA consensus guideline and the CORADS scoring system. Data were divided into two main groups—non-COVID-19 and COVID-19 pneumonia—and compared statistically with chi-squared tests and multiple regression analysis of independent variables. Results. RSNA and CORADS classifications of CT scan images were able to successfully differentiate between positive and negative COVID-19 pneumonia patients. Statistically significant differences were found between the two patient groups in various categories including the percentage of involvement, number of lesions, distribution preference, dominant pattern, nodule, tree in bud, interstitial changes, crazy paving, reverse halo vascular enlargement, peribronchial wall thickness, air trapping, pleural retraction, pleural/pericardial effusion, cavitation, and mediastinal/hilar lymphadenopathy (p
- Published
- 2022
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