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4. Long-term Outcomes with Spinal versus General Anesthesia for Hip Fracture Surgery: A Randomized Trial

Author

Vail, Emily A., Feng, Rui, Sieber, Frederick, Carson, Jeffrey L., Ellenberg, Susan S., Magaziner, Jay, Dillane, Derek, Marcantonio, Edward R., Sessler, Daniel I., Ayad, Sabry, Stone, Trevor, Papp, Steven, Donegan, Derek, Mehta, Samir, Schwenk, Eric S., Marshall, Mitchell, Jaffe, J. Douglas, Luke, Charles, Sharma, Balram, Azim, Syed, Hymes, Robert, Chin, Ki-Jinn, Sheppard, Richard, Perlman, Barry, Sappenfield, Joshua, Hauck, Ellen, Tierney, Ann, Horan, Annamarie D., Neuman, Mark D., Looke, Thomas, Bent, Sandra, Franco-Mora, Ariana, Hedrick, Pamela, Newbern, Matthew, Tadros, Rafik, Pealer, Karen, Vlassakov, Kamen, Buckley, Carolyn, Gavin, Lauren, Gorbatov, Svetlana, Gosnell, James, Steen, Talora, Vafai, Avery, Zeballos, Jose, Hruslinski, Jennifer, Cardenas, Louis, Berry, Ashley, Getchell, John, Quercetti, Nicholas, Hassan, Manal, Bajracharya, Gauasan, Billow, Damien, Bloomfield, Michael, Cuko, Evis, Elyaderani, Mehrun K., Hampton, Robert, Honar, Hooman, Khoshknabi, Dilara, Kim, Daniel, Krahe, David, Lew, Michael M., Maheshwer, Conjeevram B., Niazi, Azfar, Saha, Partha, Salih, Ahmed, de Swart, Robert J., Volio, Andrew, Bolkus, Kelly, DeAngelis, Matthew, Dodson, Gregory, Gerritsen, Jeffrey, McEniry, Brian, Mitrev, Ludmil, Kwofie, M. Kwesi, Belliveau, Anne, Bonazza, Flynn, Lloyd, Vera, Panek, Izabela, Dabiri, Jared, Chavez, Chris, Craig, Jason, Davidson, Todd, Dietrichs, Chad, Fleetwood, Cheryl, Foley, Mike, Getto, Chris, Hailes, Susie, Hermes, Sarah, Hooper, Andy, Koener, Greg, Kohls, Kate, Law, Leslie, Lipp, Adam, Losey, Allison, Nelson, William, Nieto, Mario, Rogers, Pam, Rutman, Steve, Scales, Garrett, Sebastian, Barbara, Stanciu, Tom, Lobel, Gregg, Giampiccolo, Michelle, Herman, Dara, Kaufman, Margit, Murphy, Bryan, Pau, Clara, Puzio, Thomas, Veselsky, Marlene, Apostle, Kelly, Boyer, Dory, Chen Fan, Brenda, Lee, Susan, Lemke, Mike, Merchant, Richard, Moola, Farhad, Payne, Kyrsten, Perey, Bertrand, Viskontas, Darius, Poler, Mark, D’Antonio, Patricia, O’Neill, Greg, Abdullah, Amer, Fish-Fuhrmann, Jamie, Giska, Mark, Fidkowski, Christina, Guthrie, Stuart Trent, Hakeos, William, Hayes, Lillian, Hoegler, Joseph, Nowak, Katherine, Beck, Jeffery, Cuff, Jaslynn, Gaski, Greg, Haaser, Sharon, Holzman, Michael, Malekzadeh, A. Stephen, Ramsey, Lolita, Schulman, Jeff, Schwartzbach, Cary, Azefor, Tangwan, Davani, Arman, Jaberi, Mahmood, Masear, Courtney, Haider, Syed Basit, Chungu, Carolyn, Ebrahimi, Ali, Fikry, Karim, Marcantonio, Andrew, Shelvan, Anitha, Sanders, David, Clarke, Collin, Lawendy, Abdel, Schwartz, Gary, Garg, Mohit, Kim, Joseph, Caruci, Juan, Commeh, Ekow, Cuevas, Randy, Cuff, Germaine, Franco, Lola, Furgiuele, David, Giuca, Matthew, Allman, Melissa, Barzideh, Omid, Cossaro, James, D’Arduini, Armando, Farhi, Anita, Gould, Jason, Kafel, John, Patel, Anuj, Peller, Abraham, Reshef, Hadas, Safur, Mohammed, Toscano, Fiore, Tedore, Tiffany, Akerman, Michael, Brumberger, Eric, Clark, Sunday, Friedlander, Rachel, Jegarl, Anita, Lane, Joseph, Lyden, John P., Mehta, Nili, Murrell, Matthew T., Painter, Nathan, Ricci, William, Sbrollini, Kaitlyn, Sharma, Rahul, Steel, Peter A.D., Steinkamp, Michele, Weinberg, Roniel, Stephenson Wellman, David, Nader, Antoun, Fitzgerald, Paul, Ritz, Michaela, Bryson, Greg, Craig, Alexandra, Farhat, Cassandra, Gammon, Braden, Gofton, Wade, Harris, Nicole, Lalonde, Karl, Liew, Allan, Meulenkamp, Bradley, Sonnenburg, Kendra, Wai, Eugene, Wilkin, Geoffrey, Troxell, Karen, Alderfer, Mary Ellen, Brannen, Jason, Cupitt, Christopher, Gerhart, Stacy, McLin, Renee, Sheidy, Julie, Yurick, Katherine, Chen, Fei, Dragert, Karen, Kiss, Geza, Malveaux, Halina, McCloskey, Deborah, Mellender, Scott, Mungekar, Sagar S., Noveck, Helaine, Sagebien, Carlos, Biby, Luat, McKelvy, Gail, Richards, Anna, Abola, Ramon, Ayala, Brittney, Halper, Darcy, Mavarez, Ana, Rizwan, Sabeen, Choi, Stephen, Awad, Imad, Flynn, Brendan, Henry, Patrick, Jenkinson, Richard, Kaustov, Lilia, Lappin, Elizabeth, McHardy, Paul, Singh, Amara, Donnelly, Joanne, Gonzalez, Meera, Haydel, Christopher, Livelsberger, Jon, Pazionis, Theresa, Slattery, Bridget, Vazquez-Trejo, Maritza, Baratta, Jaime, Cirullo, Michael, Deiling, Brittany, Deschamps, Laura, Glick, Michael, Katz, Daniel, Krieg, James, Lessin, Jennifer, Mojica, Jeffrey, Torjman, Marc, Jin, Rongyu, Salpeter, Mary Jane, Powell, Mark, Simmons, Jeffrey, Lawson, Prentiss, Kukreja, Promil, Graves, Shanna, Sturdivant, Adam, Bryant, Ayesha, Crump, Sandra Joyce, Verrier, Michelle, Green, James, Menon, Matthew, Applegate, Richard, Arias, Ana, Pineiro, Natasha, Uppington, Jeffrey, Wolinsky, Phillip, Gunnett, Amy, Hagen, Jennifer, Harris, Sara, Hollen, Kevin, Holloway, Brian, Horodyski, Mary Beth, Pogue, Trevor, Ramani, Ramachandran, Smith, Cameron, Woods, Anna, Warrick, Matthew, Flynn, Kelly, Mongan, Paul, Ranganath, Yatish, Fernholz, Sean, Ingersoll-Weng, Esperanza, Marian, Anil, Seering, Melinda, Sibenaller, Zita, Stout, Lori, Wagner, Allison, Walter, Alicia, Wong, Cynthia, Orwig, Denise, Goud, Maithri, Helker, Chris, Mezenghie, Lydia, Montgomery, Brittany, Preston, Peter, Schwartz, J. Sanford, Weber, Ramona, Fleisher, Lee A., Mehta, Samir, Stephens-Shields, Alisa J., Dinh, Cassandra, Schwartz, Aron, Chelly, Jacques E., Goel, Shiv, Goncz, Wende, Kawabe, Touichi, Khetarpal, Sharad, Monroe, Amy, Shick, Vladislav, Breidenstein, Max, Dominick, Timothy, Friend, Alexander, Mathews, Donald, Lennertz, Richard, Sanders, Robert, Akere, Helen, Balweg, Tyler, Bo, Amber, Doro, Christopher, Goodspeed, David, Lang, Gerald, Parker, Maggie, Rettammel, Amy, Roth, Mary, White, Marissa, Whiting, Paul, Allen, Brian F.S., Baker, Tracie, Craven, Debra, McEvoy, Matt, Turnbo, Teresa, Kates, Stephen, Morgan, Melanie, Willoughby, Teresa, Weigel, Wade, Auyong, David, Fox, Ellie, Welsh, Tina, Cusson, Bruce, Dobson, Sean, Edwards, Christopher, Harris, Lynette, Henshaw, Daryl, Johnson, Kathleen, McKinney, Glen, Miller, Scott, Reynolds, Jon, Segal, B. Scott, Turner, Jimmy, VanEenenaam, David, Weller, Robert, Lei, Jineli, Treggiari, Miriam, Akhtar, Shamsuddin, Blessing, Marcelle, Johnson, Chanel, Kampp, Michael, Kunze, Kimberly, OʼConnor, Mary, Gaskins, Lakisha J., Looke, Thomas, Tadros, Rafik, Vlassakov, Kamen, Cardenas, Louis, Hassan, Manal, Bolkus, Kelly, Mitrev, Ludmil, Kwofie, M. Kwesi, Dabiri, Jared, Lobel, Gregg, Poler, Mark, Giska, Mark, Sanders, David, Schwartz, Gary, Giuca, Matthew, Tedore, Tiffany, Nader, Antoun, Papp, Stephen, Bryson, Greg, Troxell, Karen, Kiss, Geza, Choi, Stephen, Powell, Mark, Applegate, Richard, Warrick, Matthew, Ranganath, Yatish, Elkassabany, Nabil, Chelly, Jacques E., Hoeft, Mark A., Lennertz, Richard, Sanders, Robert, Allen, Brian F.S., Kates, Stephen, Weigel, Wade, Li, Jinlei, Wijeysundera, Duminda N., Kheterpal, Sachin, Moore, Reneé H., Smith, Alexander K., Tosi, Laura L., Elkassabany, Nabil, Looke, Thomas, Menio, Diane, Mehta, Samir, Fleisher, Lee, Menio, Diane, Hruslinski, Jennifer, Ramsey, Lolita, Gaskins, Lakisha J., Langlois, Christine, Gaskins, Lakisha J., Mezenghie, Lydia, Montgomery, Brittany, Oduwole, Samuel, and Rose, Thomas

Published
2024
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6. Effect of Aspirin Versus Low-Molecular-Weight Heparin Thromboprophylaxis on Medication Satisfaction and Out-of-Pocket Costs: A Secondary Analysis of a Randomized Clinical Trial

Author

O’Hara, Nathan N., Frey, Katherine P., Stein, Deborah M., Levy, Joseph F., Slobogean, Gerard P., Castillo, Renan, Firoozabadi, Reza, Karunakar, Madhav A., Gary, Joshua L., Obremskey, William T., Seymour, Rachel B., Cuschieri, Joseph, Mullins, C. Daniel, O’Toole, Robert V., Carlini, Anthony R., Fowler, Brianna E., Taylor, Tara J., Wegener, Stephen T., Weston-Farber, Elias, Herndon, Steven Craig, Marvel, Debra, Jurkovich, Gregory J., Lee, Christopher, Malhotra, Ajai K., Riedel, Matthew D., DeCoster, Thomas A., Vercellotti, Gregory M., Wells, Jeffrey L., Westrick, Edward R., Bosse, Michael J., Christmas, A. Britton, Cunningham, Kyle William, Hsu, Joseph R., Huynh, Toan, Jacobs, David George, Kempton, Laurence B., Sims, Stephen H., Churchill, Christine, Carroll, Eben A., Babcock, Sharon, Miller, Preston R., Pilson, Holly T., Goodman, James Brett, Holden, Martha B., Weaver, Michael J., Esposito, John G., Goldhaber, Samuel Z., Heng, Marilyn, McGovern, Madeline M., Velmahos, George C., von Keudell, Arvind, Rivera, Jessica C., Gitajn, Ida Leah, Schneider, Prism S., Buckley, Richard E., Gallant, Jodi, McKay, Paula, Kleweno, Conor P., Agel, Julie, Natoli, Roman M., Gaski, Greg E., Heincelman, Carrie L., Jang, Yohan, Lopas, Luke A., McKinley, Todd O., Richard, Raveesh Daniel, Sorkin, Anthony T., Virkus, Walter, Hill, Lauren C., Hymes, Robert A., Holzman, Michael, Panjshiri, Farhanaz, Schulman, Jeff E., Ramsey, Lolita, Cuff, Jaslynn A.N., Haut, Elliott R., Warner, Stephen J., Cotton, Bryan A., Guevara, Keyla D., Claridge, Jeffrey A., Vallier, Heather A., Breslin, Mary A., Connelly, Daniel, Ghulam, Qasim M., Haac, Bryce E., LeBrun, Christopher T., Manson, Theodore T., Nascone, Jason, Pensy, Raymond A., Pollak, Andrew N., Udogwu, Ugochukwu N., Burke, Cynthia Elaine, Degani, Yasmin, DeLeon, Genaro A., Hannan, Zachary D., Healey, Kathleen M., Howe, Andrea L., Marinos, Dimitrius P., McKegg, Phillip C., McKibben, Natasha S., Zingas, Nicolas H., Evans, Andrew R., Askam, Brad M., Boulton, Christina, Weinlein, John C., Bergin, Patrick F., Bergin, Patrick F., Kutcher, Matthew E., Morellato, John, Nehete, Priyanka V., Yener, Ugur, Whiting, Paul S., Domes, Christopher, Kuhn, Gabrielle R., Gajari, Vamshi, Moreno-Diaz, Andres Fidel, Rodriguez-Baron, Elsa B., Rodriguez-Buitrago, Andres, Stinner, Daniel J., Trochez, Karen M., DePalo, Peter, Kennedy, Leah C., Lienhard, Karin, Martin, Ryan, Yee, Stephanie C., Leonard, Jordan, Arif, Hikmatullah, Brown, Krista, Deeter, Lakye Lenee, Sardesai, Neil, Bangura, Abdulai T., Demyanovich, Haley K., Eglseder, W. Andrew, Gupta, Jayesh, Isaac, Marckenley, Mulliken, Alexandra, Crisco, MJ., Lueckel, Stephanie N., Brown, Gregory A., Breazeale, Stephen, Fisher, Stephen N., Wild, Jason R., Beebe, Michael J., Khanna, Rajinder M., Brauer, Deborah, and Boyce, Robert H.

Published
2024
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7. Risk-stratified thromboprophylaxis effects of aspirin versus low-molecular-weight heparin in orthopedic trauma patients: A secondary analysis of the PREVENT CLOT trial

Author

OʼHara, Nathan N., OʼToole, Robert V., Frey, Katherine P., Castillo, Renan C., Cuschieri, Joseph, Haut, Elliott R., Slobogean, Gerard P., Firoozabadi, Reza, Christmas, A. Britton, Obremskey, William T., Carlini, Anthony R., Gaski, Greg E., Kutcher, Matthew E., Marvel, Debra, Stein, Deborah M., Levy, Joseph F., Wegener, Stephen T., Fowler, Brianna E., Taylor, Tara J., Weston-Farber, Elias, Herndon, Steven Craig, Jr., DeCoster, Thomas A., Jurkovich, Gregory J., Lee, Christopher, Malhotra, Ajai K., Riedel, Matthew D., Wells, Jeffrey L., Altman, Daniel T., Westrick, Edward R., Bosse, Michael J., Karunakar, Madhav A., Cunningham, Kyle W., Huynh, Toan, Jacobs, David G., Kempton, Laurence B., Phelps, Kevin D., Seymour, Rachel B., Sims, Stephen H., Churchill, Christine, Carroll, Eben A., Babcock, Sharon, Miller, Preston R., Pilson, Holly T., Goodman, James Brett, Weaver, Michael J., Esposito, John G., Goldhaber, Samuel Zachary, Heng, Marilyn, McGovern, Madeline M., Velmahos, George C., von Keudell, Arvind G., Rivera, Jessica C., Gitajn, Ida Leah, Schneider, Prism S., Buckley, Richard E., Johal, Herman S., Gallant, Jodi L., McKay, Paula, Kleweno, Conor P., Agel, Julie, Arif, Hikmatullah, McKinley, Todd O., Natoli, Roman M., Heincelman, Carrie L., Jang, Yohan, Lopas, Luke A., Mullis, Brian H., Richard, Raveesh D., Virkus, Walter, Hill, Lauren C., Hymes, Robert A., Holzman, Michael, Malekzadeh, A. Stephen, Panjshiri, Farhanaz, Schulman, Jeff E., Ramsey, Lolita, Ahn, James, Cuff, Jaslynn A. N., Gary, Joshua L., Warner, Stephen J., Cotton, Bryan A., Vallier, Heather A., Claridge, Jeffrey A., Breslin, Mary A., Cowley, R Adams, Connelly, Daniel, Eglseder, W. Andrew, Haac, Bryce E., Healey, Kathleen Marie, LeBrun, Christopher T., Manson, Theodore, McKibben, Natasha S., Mulliken, Alexandra, Nascone, Jason, Pensy, Raymond A., Pollak, Andrew N., Sciadini, Marcus F., Udogwu, Ugochukwu N., Zingas, Nicolas, Burke, Cynthia Elaine, DeLeon, Genaro A., Hannan, Zachary D., Howe, Andrea L., Marinos, Dimitrius P., McKegg, Phillip C., Evans, Andrew R., Askam, Brad M., Joseph, Bellal, Lowe, Jason, Weinlein, John C., Bergin, Patrick F., Bhanat, Eldrin L., Khanna, Rajinder, Morellato, John, Nehete, Priyanka V., Domes, Christopher, Whiting, Paul S., Goodspeed, David C., Kuhn, Gabrielle R., Guillamondegui, Oscar D., Moreno-Diaz, Andres Fidel, Stinner, Daniel J., Pritchett, Charles, Jr., and Trochez, Karen M.

Published
2024
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8. Implementing stakeholder engagement to explore alternative models of consent: An example from the PREP-IT trials.

Author

Pechero, Guillermo, Pfaff, Branden, Rao, Mayank, Pogorzelski, David, McKay, Paula, Spicer, Ella, Howe, Andrea, Demyanovich, Haley K, Sietsema, Debra L, McTague, Michael F, Ramsey, Lolita, Holden, Martha, Rudnicki, Joshua, Wells, Jeff, Medeiros, Michelle, Slobogean, Gerard P, Sprague, Sheila, PREP-IT Investigators, Wells, Jeffrey, Bhandari, Mohit, Steering Committee, Adjudication Committee, Data and Safety Monitoring Committee, Research Methodology Core, Patient Centred Outcomes Core, Orthopaedic Surgery Core, Operating Room Core, Infectious Disease Core, Military Core, PREP-IT Clinical Sites, O'Toole, Robert V, D'Alleyrand, Jean-Claude, Eglseder, Andrew, Johnson, Aaron, Langhammer, Christopher, Lebrun, Christopher, Manson, Theodore, Nascone, Jason, Paryavi, Ebrahim, Pensy, Raymond, Pollak, Andrew, Sciadini, Marcus, Degani, Yasmin, O'Hara, Nathan N, Joseph, Katherine, Camara, Megan, Aqueous-PREP and PREPARE, Aqueous-PREP, and PREPARE

Subjects
PREP-IT Investigators, Steering Committee, Adjudication Committee, Data and Safety Monitoring Committee, Research Methodology Core, Patient Centred Outcomes Core, Orthopaedic Surgery Core, Operating Room Core, Infectious Disease Core, Military Core, PREP-IT Clinical Sites, Aqueous-PREP and PREPARE, Aqueous-PREP, PREPARE, Cluster randomized crossover, Consent, Deferred consent, Patient advisors, Stakeholder engagement, Trial design
Abstract

IntroductionCluster randomized crossover trials are often faced with a dilemma when selecting an optimal model of consent, as the traditional model of obtaining informed consent from participant's before initiating any trial related activities may not be suitable. We describe our experience of engaging patient advisors to identify an optimal model of consent for the PREP-IT trials. This paper also examines surrogate measures of success for the selected model of consent.MethodsThe PREP-IT program consists of two multi-center cluster randomized crossover trials that engaged patient advisors to determine an optimal model of consent. Patient advisors and stakeholders met regularly and reached consensus on decisions related to the trial design including the model for consent. Patient advisors provided valuable insight on how key decisions on trial design and conduct would be received by participants and the impact these decisions will have.ResultsPatient advisors, together with stakeholders, reviewed the pros and cons and the requirements for the traditional model of consent, deferred consent, and waiver of consent. Collectively, they agreed upon a deferred consent model, in which patients may be approached for consent after their fracture surgery and prior to data collection. The consent rate in PREP-IT is 80.7%, and 0.67% of participants have withdrawn consent for participation.DiscussionInvolvement of patient advisors in the development of an optimal model of consent has been successful. Engagement of patient advisors is recommended for other large trials where the traditional model of consent may not be optimal.

Published
2021

9. Managing work flow in high enrolling trials: The development and implementation of a sampling strategy in the PREPARE trial.

Author

Pogorzelski, David, Nguyen, Uyen, McKay, Paula, Thabane, Lehana, Camara, Megan, Ramsey, Lolita, Seymour, Rachel, Goodman, J Brett, McGee, Sheketha, Fraifogl, Joanne, Hudgins, Andrea, Tanner, Stephanie L, Bhandari, Mohit, Slobogean, Gerard P, Sprague, Sheila, PREP-IT Investigators Executive Committee:, Steering Committee, Adjudication Committee, Data and Safety Monitoring Committee, Research Methodology Core, Patient Centred Outcomes Core, Orthopaedic Surgery Core, Operating Room Core, Infectious Disease Core, Military Core, McMaster University Methods Center, University of Maryland School of Medicine Administrative Center, University of Maryland School of Pharmacy, The PATIENTS Program, PREP-IT Clinical Sites: Lead Clinical Site (Aqueous-PREP and PREPARE), Aqueous-PREP and PREPARE, Aqueous-PREP, PREPARE, and PREP-IT Investigators Executive Committee

Subjects
PREP-IT Investigators Executive Committee:, Steering Committee, Adjudication Committee, Data and Safety Monitoring Committee, Research Methodology Core, Patient Centred Outcomes Core, Orthopaedic Surgery Core, Operating Room Core, Infectious Disease Core, Military Core, McMaster University Methods Center, University of Maryland School of Medicine Administrative Center, University of Maryland School of Pharmacy, The PATIENTS Program, PREP-IT Clinical Sites: Lead Clinical Site, Aqueous-PREP and PREPARE, Aqueous-PREP, PREPARE, PREP-IT Investigators Executive Committee, Cluster crossover, Pragmatic, Sampling, Sampling framework, Sampling strategy, Work flow
Abstract

IntroductionPragmatic trials in comparative effectiveness research assess the effects of different treatment, therapeutic, or healthcare options in clinical practice. They are characterized by broad eligibility criteria and large sample sizes, which can lead to an unmanageable number of participants, increasing the risk of bias and affecting the integrity of the trial. We describe the development of a sampling strategy tool and its use in the PREPARE trial to circumvent the challenge of unmanageable work flow.MethodsGiven the broad eligibility criteria and high fracture volume at participating clinical sites in the PREPARE trial, a pragmatic sampling strategy was needed. Using data from PREPARE, descriptive statistics were used to describe the use of the sampling strategy across clinical sites. A Chi-square test was performed to explore whether use of the sampling strategy was associated with a reduction in the number of missed eligible patients.Results7 of 20 clinical sites (35%) elected to adopt a sampling strategy. There were 1539 patients excluded due to the use of the sampling strategy, which represents 30% of all excluded patients and 20% of all patients screened for participation. Use of the sampling strategy was associated with lower odds of missed eligible patients (297/4545 (6.5%) versus 341/3200 (10.7%) p

Published
2021

10. Impact of Anesthesia selection on Post-Op Pain Management in Operatively treated Hip Fractures

Author

Churchill, Christine, Dumpe, Jarrod, Foote, Jake, Green, Anna, Huang, Nicole, Karunakar, Madhav, Khalafallah, Youssef M, Phelps, Kevin, Sims, Stephen, Li, Katherine, McKnight, R. Randall, Odum, Susan, Parham, Jeremiah, Starke, Matthew, Katsafanas, Ana, Morris, Matthew, Chintanippu, Nirupama, Rice, Olivia, Averkamp, Benjamin, Yu, Ziqing, Kempton, Laurence, Davis, Jana M, Cuadra, Mario, Roomian, Tamar, Wally, Meghan K, Seymour, Rachel B, Hymes, Robert A, Ramsey, Lolita, and Hsu, Joseph R

Published
2023
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11. Implementing stakeholder engagement to explore alternative models of consent: An example from the PREP-IT trials

Author

Slobogean, Gerard P., Bhandari, Mohit, Sprague, Sheila, D'Alleyrand, Jean-Claude, Harris, Anthony D., Mullins, Daniel C., Thabane, Lehana, Wells, Jeffrey, Wood, Amber, Della Rocca, Gregory J., Hebden, Joan, Jeray, Kyle J., Marchand, Lucas, O'Hara, Lyndsay M., Zura, Robert, Gardner, Michael J., Blasman, Jenna, Davies, Jonah, Liang, Stephen, Taljaard, Monica, Devereaux, P.J., Guyatt, Gordon H., Heels-Ansdell, Diane, Marvel, Debra, Palmer, Jana, Friedrich, Jeff, O'Hara, Nathan N., Grissom, Ms Frances, Gitajn, I. Leah, Morshed, Saam, O'Toole, Robert V., Petrisor, Bradley A., Camara, Megan, Mossuto, Franca, Joshi, Manjari G., Fowler, Justin, Rivera, Jessica, Talbot, Max, Dodds, Shannon, Garibaldi, Alisha, Li, Silvia, Nguyen, Uyen, Pogorzelski, David, Rojas, Alejandra, Scott, Taryn, Del Fabbro, Gina, Szasz, Olivia Paige, McKay, Paula, Howe, Andrea, Rudnicki, Joshua, Demyanovich, Haley, Little, Kelly, Mullins, C. Daniel, Medeiros, Michelle, Kettering, Eric, Hale, Diamond, Petrisor, Brad A., Johal, Herman, Ristevski, Bill, Williams, Dale, Denkers, Matthew, Rajaratnam, Krishan, Al-Asiri, Jamal, Leonard, Jordan, Marcano-Fernández, Francesc A., Gallant, Jodi, Persico, Federico, Gjorgjievski, Marko, George, Annie, Natoli, Roman M., Gaski, Greg E., McKinley, Todd O., Virkus, Walter W., Sorkin, Anthony T., Szatkowski, Jan P., Baele, Joseph R., Mullis, Brian H., Hill, Lauren C., Hudgins, Andrea, Osborn, Patrick, Pierrie, Sarah, Martinez, Eric, Kimmel, Joseph, Adams, John D., Beckish, Michael L., Bray, Christopher C., Brown, Timothy R., Cross, Andrew W., Dew, Timothy, Faucher, Gregory K., Gurich, Richard W., Jr., Lazarus, David E., Millon, S. John, Palmer, M. Jason, Porter, Scott E., Schaller, Thomas M., Sridhar, Michael S., Sanders, John L., Rudisill, L. Edwin, Jr., Garitty, Michael J., Poole, Andrew S., Sims, Michael L., Walker, Clark M., Carlisle, Robert M., II, Hofer, Erin Adams, Huggins, Brandon S., Hunter, Michael D., Marshall, William A., Ray, Shea Bielby, Smith, Cory D., Altman, Kyle M., Bedard, Julia C., Loeffler, Markus F., Pichiotino, Erin R., Cole, Austin A., Maltz, Ethan J., Parker, Wesley, Ramsey, T. Bennett, Burnikel, Alex, Colello, Michael, Stewart, Russell, Wise, Jeremy, Moody, M. Christian, Tanner, Stephanie L., Snider, Rebecca G., Townsend, Christine E., Pham, Kayla H., Martin, Abigail, Robertson, Emily, Miclau, Theodore, Kandemir, Utku, Marmor, Meir, Matityahu, Amir, McClellan, R. Trigg, Meinberg, Eric, Shearer, David, Toogood, Paul, Ding, Anthony, Donohoe, Erin, Murali, Jothi, Belaye, Tigist, Berhaneselase, Eleni, Paul, Alexandra, Garg, Kartik, Gary, Joshua L., Warner, Stephen J., Munz, John W., Choo, Andrew M., Achor, Timothy S., “Chip” Routt, Milton L., Rao, Mayank, Pechero, Guillermo, Miller, Adam, Hagen, Jennifer E., Patrick, Matthew, Vlasak, Richard, Krupko, Thomas, Sadasivan, Kalia, Koenig, Chris, Bailey, Daniel, Wentworth, Daniel, Van, Chi, Schwartz, Justin, Dehghan, Niloofar, Jones, Clifford B., Tracy Watson, J., McKee, Michael, Karim, Ammar, Talerico, Michael, Sietsema, Debra L., Williams, Alyse, Dykes, Tayler, Obremskey, William T., Jahangir, Amir Alex, Sethi, Manish, Boyce, Robert, Stinner, Daniel J., Mitchell, Phillip, Trochez, Karen, Rodriguez, Andres, Gajari, Vamshi, Rodriguez, Elsa, Pritchett, Charles, Boulton, Christina, Lowe, Jason, Wild, Jason, Ruth, John T., Taylor, Michel, Seach, Andrea, Saeed, Sabina, Culbert, Hunter, Cruz, Alejandro, Knapp, Thomas, Hurkett, Colin, Lowney, Maya, Prayson, Michael, Venkatarayappa, Indresh, Horne, Brandon, Jerele, Jennifer, Clark, Linda, Marcano-Fernández, Francesc, Jornet-Gibert, Montsant, Martínez-Carreres, Laia, Martí-Garín, David, Serrano-Sanz, Jorge, Sánchez-Fernández, Joel, Sanz-Molero, Matsuyama, Carballo, Alejandro, Pelfort, Xavier, Acerboni-Flores, Francesc, Alavedra-Massana, Anna, Anglada-Torres, Neus, Berenguer, Alexandre, Cámara-Cabrera, Jaume, Caparros-García, Ariadna, Fillat-Gomà, Ferran, Fuentes-López, Ruben, Garcia-Rodriguez, Ramona, Gimeno-Calavia, Nuria, Graells-Alonso, Guillem, Martínez-Álvarez, Marta, Martínez-Grau, Patricia, Pellejero-García, Raúl, Ràfols-Perramon, Ona, Peñalver, Juan Manuel, Domènech, Mònica Salomó, Soler-Cano, Albert, Velasco-Barrera, Aldo, Yela-Verdú, Christian, Bueno-Ruiz, Mercedes, Sánchez-Palomino, Estrella, Guerra-Farfan, Ernesto, Tomas-Hernandez, Jordi, Teixidor-Serra, Jordi, Molero-Garcia, Vicente, Selga-Marsa, Jordi, Porcel-Vasquez, Juan Antonio, Andres-Peiro, Jose Vicente, Minguell-Monyart, Joan, Garcia-Sanchez, Yaiza, Nuñez-Camarena, Jorge, Tauste-Rubio, Eladia, Gonzalez-Amigo, Marta, Romeo, Nicholas M., Vallier, Heather A., Breslin, Mary A., Fraifogl, Joanne, Wilson, Eleanor S., Wadenpfuhl, Leanne K., Halliday, Paul G., Viskontas, Darius G., Apostle, Kelly L., Boyer, Dory S., Moola, Farhad O., Perey, Bertrand H., Stone, Trevor B., Lemke, H. Michael, Zomar, Mauri, Spicer, Ella, Fan, Chen “Brenda”, Payne, Kyrsten, Phelps, Kevin, Bosse, Michael, Karunakar, Madhav, Kempton, Laurence, Sims, Stephen, Hsu, Joseph, Seymour, Rachel, Churchill, Christine, Bartel, Claire, Mayberry, Robert Miles, Brownrigg, Maggie, Girardi, Cara, Mayfield, Ada, Hymes, Robert A., Schwartzbach, Cary C., Schulman, Jeff E., Malekzadeh, A. Stephen, Holzman, Michael A., Ramsey, Lolita, Ahn, James S., Panjshiri, Farhanaz, Das, Sharmistha, English, Antoinisha D., Haaser, Sharon M., Cuff, Jaslynn A.N., Pilson, Holly, Carroll, Eben A., Halvorson, Jason J., Babcock, Sharon, Goodman, J. Brett, Holden, Martha B., Bullard, Debra, Williams, Wendy, Higgins, Thomas F., Haller, Justin M., Rothberg, David L., Marchand, Lucas S., Neese, Ashley, Russell, Mark, Olsen, Zachary M., Coe, Marcus, Dwyer, Kevin, Mullin, Devin S., Reilly, Clifford A., DePalo, Peter, Hall, Amy E., Heng, Marilyn, Harris, Mitchel B., Smith, R. Malcolm, Lhowe, David W., Esposito, John G., Bansal, Mira, Bergin, Patrick F., Russell, George V., Graves, Matthew L., Morellato, John, Champion, Heather K., Johnson, Leslie N., McGee, Sheketha L., Bhanat, Eldrin L., Mehta, Samir, Donegan, Derek, Ahn, Jaimo, Horan, Annamarie, Dooley, Mary, Kuczinski, Ashley, Iwu, Ashley, Potter, David, VanDemark, Robert, III, Pfaff, Branden, Hollinsworth, Troy, Weaver, Michael J., von Keudell, Arvind G., McTague, Michael F., Allen, Elizabeth M., Jaeblon, Todd, Beer, Robert, Demyanovich, Haley K., Gage, Mark J., Reilly, Rachel M., Sparrow, Cindy, Pechero, Guillermo, Jr., Holden, Martha, Wells, Jeff, Eglseder, Andrew, Johnson, Aaron, Langhammer, Christopher, Lebrun, Christopher, Manson, Theodore, Nascone, Jason, Paryavi, Ebrahim, Pensy, Raymond, Pollak, Andrew, Sciadini, Marcus, Degani, Yasmin, and Joseph, Katherine

Published
2021
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12. Managing work flow in high enrolling trials: The development and implementation of a sampling strategy in the PREPARE trial

Author

Slobogean, Gerard P., Sprague, Sheila, Wells, Jeffrey, Bhandari, Mohit, D'Alleyrand, Jean-Claude, Harris, Anthony D., Mullins, Daniel C., Thabane, Lehana, Wood, Amber, Della Rocca, Gregory J., Hebden, Joan, Jeray, Kyle J., Marchand, Lucas, O'Hara, Lyndsay M., Zura, Robert, Gardner, Michael J., Blasman, Jenna, Davies, Jonah, Liang, Stephen, Taljaard, Monica, Devereaux, P.J., Guyatt, Gordon H., Heels-Ansdell, Diane, Marvel, Debra, Palmer, Jana, Friedrich, Jeff, O'Hara, Nathan N., Grissom, Ms. Frances, Gitajn, I. Leah, Morshed, Saam, O'Toole, Robert V., Petrisor, Bradley A., Camara, Megan, Mossuto, Franca, Joshi, Manjari G., Fowler, Justin, Rivera, Jessica, Talbot, Max, Dodds, Shannon, Garibaldi, Alisha, Li, Silvia, Nguyen, Uyen, Pogorzelski, David, Rojas, Alejandra, Scott, Taryn, Del Fabbro, Gina, Szasz, Olivia Paige, McKay, Paula, Howe, Andrea, Rudnicki, Joshua, Demyanovich, Haley, Little, Kelly, Mullins, C. Daniel, Medeiros, Michelle, Kettering, Eric, Hale, Diamond, Eglseder, Andrew, Johnson, Aaron, Langhammer, Christopher, Lebrun, Christopher, Manson, Theodore, Nascone, Jason, Paryavi, Ebrahim, Pensy, Raymond, Pollak, Andrew, Sciadini, Marcus, Degani, Yasmin, Demyanovich, Haley K., Joseph, Katherine, Petrisor, Brad A., Johal, Herman, Ristevski, Bill, Williams, Dale, Denkers, Matthew, Rajaratnam, Krishan, Al-Asiri, Jamal, Leonard, Jordan, Marcano-Fernández, Francesc A., Gallant, Jodi, Persico, Federico, Gjorgjievski, Marko, George, Annie, Natoli, Roman M., Gaski, Greg E., McKinley, Todd O., Virkus, Walter W., Sorkin, Anthony T., Szatkowski, Jan P., Baele, Joseph R., Mullis, Brian H., Hill, Lauren C., Hudgins, Andrea, Osborn, Patrick, Pierrie, Sarah, Martinez, Eric, Kimmel, Joseph, Adams, John D., Beckish, Michael L., Bray, Christopher C., Brown, Timothy R., Cross, Andrew W., Dew, Timothy, Faucher, Gregory K., Gurich, Richard W., Jr., Lazarus, David E., Millon, S. John, Palmer, M. Jason, Porter, Scott E., Schaller, Thomas M., Sridhar, Michael S., Sanders, John L., Rudisill, L. Edwin, Jr., Garitty, Michael J., Poole, Andrew S., Sims, Michael L., Walker, Clark M., Carlisle, Robert M., II, Hofer, Erin Adams, Huggins, Brandon S., Hunter, Michael D., Marshall, William A., Ray, Shea Bielby, Smith, Cory D., Altman, Kyle M., Bedard, Julia C., Loeffler, Markus F., Pichiotino, Erin R., Cole, Austin A., Maltz, Ethan J., Parker, Wesley, Ramsey, T. Bennett, Burnikel, Alex, Colello, Michael, Stewart, Russell, Wise, Jeremy, Moody, M. Christian, Tanner, Stephanie L., Snider, Rebecca G., Townsend, Christine E., Pham, Kayla H., Martin, Abigail, Robertson, Emily, Miclau, Theodore, Kandemir, Utku, Marmor, Meir, Matityahu, Amir, McClellan, R. Trigg, Meinberg, Eric, Shearer, David, Toogood, Paul, Ding, Anthony, Donohue, Erin, Belaye, Tigist, Berhaneselase, Eleni, Paul, Alexandra, Garg, Kartik, Gary, Joshua L., Warner, Stephen J., Munz, John W., Choo, Andrew M., Achor, Timothy S., “Chip” Routt, Milton L., Rao, Mayank, Pechero, Guillermo, Miller, Adam, Hagen, Jennifer E., Patrick, Matthew, Vlasak, Richard, Krupko, Thomas, Sadasivan, Kalia, Koenig, Chris, Bailey, Daniel, Wentworth, Daniel, Van, Chi, Schwartz, Justin, Dehghan, Niloofar, Jones, Clifford B., Watson, J Tracy, McKee, Michael, Karim, Ammar, Talerico, Michael, Sietsema, Debra L., Williams, Alyse, Dykes, Tayler, Obremskey, William T., Jahangir, Amir Alex, Sethi, Manish, Boyce, Robert, Stinner, Daniel J., Mitchell, Phillip, Trochez, Karen, Rodriguez, Andres, Gajari, Vamshi, Rodriguez, Elsa, Pritchett, Charles, Boulton, Christina, Lowe, Jason, Wild, Jason, Ruth, John T., Taylor, Michel, Seach, Andrea, Saeed, Sabina, Culbert, Hunter, Cruz, Alejandro, Knapp, Thomas, Hurkett, Colin, Lowney, Maya, Prayson, Michael, Venkatarayappa, Indresh, Horne, Brandon, Jerele, Jennifer, Clark, Linda, Marcano-Fernández, Francesc, Jornet-Gibert, Montsant, Martínez-Carreres, Laia, Martí-Garín, David, Serrano-Sanz, Jorge, Sánchez-Fernández, Joel, Sanz-Molero, Matsuyama, Carballo, Alejandro, Pelfort, Xavier, Acerboni-Flores, Francesc, Alavedra-Massana, Anna, Anglada-Torres, Neus, Berenguer, Alexandre, Cámara-Cabrera, Jaume, Caparros-García, Ariadna, Fillat-Gomà, Ferran, Fuentes-López, Ruben, Garcia-Rodriguez, Ramona, Gimeno-Calavia, Nuria, Graells-Alonso, Guillem, Martínez-Álvarez, Marta, Martínez-Grau, Patricia, Pellejero-García, Raúl, Ràfols-Perramon, Ona, Peñalver, Juan Manuel, Domènech, Mònica Salomó, Soler-Cano, Albert, Velasco-Barrera, Aldo, Yela-Verdú, Christian, Bueno-Ruiz, Mercedes, Sánchez-Palomino, Estrella, Guerra, Ernesto, García, Yaiza, Romeo, Nicholas M., Vallier, Heather A., Breslin, Mary A., Fraifogl, Joanne, Wilson, Eleanor S., Wadenpfuhl, Leanne K., Halliday, Paul G., Viskontas, Darius G., Apostle, Kelly L., Boyer, Dory S., Moola, Farhad O., Perey, Bertrand H., Stone, Trevor B., Lemke, H. Michael, Zomar, Mauri, Spicer, Ella, Fan, Chen “Brenda”, Payne, Kyrsten, Phelps, Kevin, Bosse, Michael, Karunakar, Madhav, Kempton, Laurence, Sims, Stephen, Hsu, Joseph, Seymour, Rachel, Churchill, Christine, Bartel, Claire, Mayberry, Robert Miles, Brownrigg, Maggie, Girardi, Cara, Mayfield, Ada, Hymes, Robert A., Schwartzbach, Cary C., Schulman, Jeff E., Malekzadeh, A. Stephen, Holzman, Michael A., Ramsey, Lolita, Ahn, James S., Panjshiri, Farhanaz, Das, Sharmistha, English, Antoinisha D., Haaser, Sharon M., Cuff, Jaslynn A.N., Pilson, Holly, Carroll, Eben A., Halvorson, Jason J., Babcock, Sharon, Goodman, J. Brett, Holden, Martha B., Bullard, Debra, Williams, Wendy, Higgins, Thomas F., Haller, Justin M., Rothberg, David L., Neese, Ashley, Russell, Mark, Coe, Marcus, Dwyer, Kevin, Mullin, Devin S., Reilly, Clifford A., DePalo, Peter, Hall, Amy E., Heng, Marilyn, Harris, Mitchel B., Smith, R. Malcolm, Lhowe, David W., Esposito, John G., Bansal, Mira, Bergin, Patrick F., Russell, George V., Graves, Matthew L., Morellato, John, Champion, Heather K., Johnson, Leslie N., McGee, Sheketha L., Bhanat, Eldrin L., Mehta, Samir, Donegan, Derek, Ahn, Jaimo, Horan, Annamarie, Dooley, Mary, Kuczinski, Ashley, Iwu, Ashley, Potter, David, VanDemark, Robert, III, Pfaff, Branden, Hollinsworth, Troy, Weaver, Michael J., von Keudell, Arvind G., McTague, Michael F., Allen, Elizabeth M., Jaeblon, Todd, Beer, Robert, Gage, Mark J., Reilly, Rachel M., Sparrow, Cindy, and McGee, Sheketha

Published
2021
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13. Engaging patients as partners in a multicentre trial of spinal versus general anaesthesia for older adults

Author

Looke, Thomas, Bent, Sandra, Franco-Mora, Ariana, Hedrick, Pamela, Newbern, Matthew, Tadros, Rafik, Pealer, Karen, Marcantonio, Edward, Vlassakov, Kamen, Buckley, Carolyn, Gorbatov, Svetlana, Gosnell, James, Steen, Talora, Vafai, Avery, Zeballos, Jose, Cardenas, Louis, Berry, Ashley, Getchell, John, Quercetti, Nicholas, Sessler, Daniel I., Ayad, Sabry, Hassan, Manal, Ali, Assad, Bajracharya, Gauasan, Billow, Damien, Bloomfield, Michael, Elliott, Kavita, Hampton, Robert, He, Linda, Honar, Hooman, Khoshknabi, Dilara, Kim, Daniel, Minko, Paul, Morris, Adam, Niazi, Azfar, Nutcharoen, Tara, Roberts, Jeffrey, Saha, Partha, Salih, Ahmed, Skolaris, Alexis, Stang, Taylor, Strimbu, Victor, Templeton, Jesse, Volio, Andrew, Wang, Jiayi, Bolkus, Kelly, DeAngelis, Matthew, Dodson, Gregory, Gerritsen, Jeffrey, McEniry, Brian, Mitrev, Ludmil, Kwofie, Kwesi, Bonazza, Flynn, Lloyd, Vera, Panek, Izabela, Dabiri, Jared, Chavez, Chris, Craig, Jason, Davidson, Todd, Dietrichs, Chad, Fleetwood, Cheryl, Foley, Mike, Getto, Chris, Hailes, Susie, Hermes, Sarah, Hooper, Andy, Koener, Greg, Kohls, Kate, Law, Leslie, Lipp, Adam, Losey, Allison, Nelson, William, Nieto, Mario, Rogers, Pam, Rutman, Steve, Scales, Garrett, Sebastian, Barbara, Stanciu, Tom, Lobel, Gregg, Giampiccolo, Michelle, Herman, Dara, Kaufman, Margit, Murphy, Bryan, Pau, Clara, Puzio, Thomas, Veselsky, Marlene, Stone, Trevor, Apostle, Kelly, Boyer, Dory, Fan, Brenda Chen, Lee, Susan, Lemke, Mike, Merchant, Richard, Moola, Farhad, Payne, Kyrsten, Perey, Bertrand, Viskontas, Darius, Poler, Mark, D'Antonio, Patricia, Sheppard, Richard, Abdullah, Amer, Fish-Fuhrmann, Jamie, Giska, Mark, Fidkowski, Christina, Guthrie, Trent, Hakeos, William, Hayes, Lillian, Hoegler, Joseph, Nowak, Katherine, Hymes, Robert, Beck, Jeffery, Cuff, Jaslynn, Gaski, Greg, Haaser, Sharon, Holzman, Michael, Malekzadeh, A. Stephen, Ramsey, Lolita, Schulman, Jeff, Schwartzbach, Cary, Sieber, Frederick, Azefor, Tangwan, Brown, Charles, Davani, Arman, Jaberi, Mahmood, Masear, Courtney, Sharma, Balram, Haider, Syed Basit, Chungu, Carolyn, Ebrahimi, Ali, Fikry, Karim, Gannon, Kerri, Marcantonio, Andrew, Pace, Meredith, Sanders, David, Clarke, Collin, Lawendy, Abdel, Schwartz, Gary, Garg, Mohit, Kim, Joseph, Marshall, Mitchell, Caurci, Juan, Commeh, Ekow, Cuevas, Randy, Cuff, Germaine, Franco, Lola, Furguiele, David, Giuca, Matthew, Allman, Melissa, Barzideh, Omid, Cossaro, James, D'Arduini, Armando, Farhi, Anita, Gould, Jason, Kafel, John, Patel, Anuj, Peller, Abraham, Reshef, Hadas, Safur, Mohammed, Toscano, Fiore, Tedore, Tiffany, Akerman, Michael, Brumberger, Eric, Clark, Sunday, Friedlander, Rachel, Jegarl, Anita, Lane, Joseph, Lyden, John P., Mehta, Nili, Murrell, Matthew T., Painter, Nathan, Ricci, William, Sbrollini, Kaitlyn, Sharma, Rahul, Steel, Peter A.D., Steinkamp, Michele, Weinberg, Roniel, Wellman, David Stephenson, Nader, Antoun, Fitzgerald, Paul, Ritz, Michaela, Papp, Steven, Bryson, Greg, Craig, Alexandra, Farhat, Cassandra, Gammon, Braden, Gofton, Wade, Harris, Nicole, Lalonde, Karl, Liew, Allan, Meulenkamp, Bradley, Sonnenburg, Kendra, Wai, Eugene, Wilkin, Geoffrey, Donegan, Derek, Dinh, Cassandra, Elkassabany, Nabil, Horan, Annamarie, Mehta, Samir, Troxell, Karen, Alderfer, Mary Ellen, Brannen, Jason, Cupitt, Christopher, Gerhart, Stacy, McLin, Renee, Sheidy, Julie, Yurick, Katherine, Carson, Jeffrey, Chen, Fei, Dragert, Karen, Kiss, Geza, Malveaux, Halina, McCloskey, Deborah, Mellender, Scott, Mungekar, Sagar S., Noveck, Helaine, Sagebien, Carlos, Perlman, Barry, Biby, Luat, McKelvy, Gail, Richards, Anna, Azim, Syed, Abola, Ramon, Ayala, Brittney, Halper, Darcy, Mavarez, Ana, Choi, Stephen, Awad, Imad, Flynn, Brendan, Henry, Patrick, Jenkinson, Richard, Kaustov, Lilia, Lappin, Elizabeth, McHardy, Paul, Singh, Amara, Hauck, Ellen, Donnelly, Joanne, Gonzalez, Meera, Haydel, Christopher, Livelsberger, Jon, Pazionis, Theresa, Slattery, Bridget, Vazquez-Trejo, Maritza, Schwenk, Eric, Baratta, Jaime, Deiling, Brittany, Deschamps, Laura, Glick, Michael, Katz, Daniel, Krieg, James, Lessin, Jennifer, Torjman, Marc, Chin, Ki Jinn, Jin, Rongyu, Salpeter, Mary Jane, Powell, Mark, Simmons, Jeffrey, Lawson, Prentiss, Kukreja, Promil, Graves, Shanna, Sturdivant, Adam, Bryant, Ayesha, Crump, Sandra Joyce, Dillane, Derek, Taylor, Michael, Verrier, Michelle, Applegate, Richard, Arias, Ana, Pineiro, Natasha, Uppington, Jeffrey, Wolinsky, Phillip, Sappenfield, Joshua, Gunnett, Amy, Hagen, Jennifer, Harris, Sara, Hollen, Kevin, Holloway, Brian, Horodyski, Mary Beth, Pogue, Trevor, Ramani, Ramachandran, Smith, Cameron, Woods, Anna, Warrick, Matthew, Flynn, Kelly, Mongan, Paul, Ranganath, Yatish, Fernholz, Sean, Ingersoll-Weng, Esperanza, Marian, Anil, Seering, Melinda, Sibenaller, Zita, Stout, Lori, Wagner, Allison, Walter, Alicia, Wong, Cynthia, Magaziner, Jay, Orwig, Denise, Brown, Trina, Dattilo, Jim, Ellenberg, Susan, Feng, Rui, Fleisher, Lee, Gaskins, Lakisha, Goud, Maithri, Helker, Chris, Mezenghie, Lydia, Montgomery, Brittany, Preston, Peter, Stephens, Alisa, Schwartz, J. Sanford, Tierney, Ann, Weber, Ramona, Chelly, Jacques, Goel, Shiv, Goncz, Wende, Kawabe, Touichi, Khetarpal, Sharad, King, Kevin, Kunkel, Frank, Luke, Charles, Monroe, Amy, Shick, Vladislav, Silipo, Anthony, Stehle, Caroline, Szabo, Katherine, Yennam, Sudhakar, Hoeft, Mark, Breidenstein, Max, Dominick, Timothy, Friend, Alexander, Mathews, Donald, Lennertz, Richard, Akere, Helen, Balweg, Tyler, Bo, Amber, Doro, Christopher, Goodspeed, David, Lang, Gerald, Parker, Maggie, Rettammel, Amy, Roth, Mary, Sanders, Robert, White, Marissa, Whiting, Paul, Allen, Brian, Baker, Tracie, Craven, Debra, McEvoy, Matt, Turnbo, Teresa, Kates, Stephen, Morgan, Melanie, Willoughby, Teresa, Weigel, Wade, Auyong, David, Fox, Ellie, Welsh, Tina, Jaffe, J. Douglas, Cusson, Bruce, Dobson, Sean, Edwards, Christopher, Harris, Lynette, Henshaw, Daryl, Johnson, Kathleen, McKinney, Glen, Miller, Scott, Reynolds, Jon, Turner, Jimmy, VanEenenaam, David, Weller, Robert, Akhtar, Shamsuddin, Blessing, Marcelle, Johnson, Chanel, Kampp, Michael, Kunze, Kimberly, Li, Jinlei, O'Connor, Mary, Treggiari, Miriam, Hruslinski, Jennifer, Menio, Diane A., Hymes, Robert A., Langlois, Christine, Gaskins, Lakisha J., and Neuman, Mark D.

Published
2021
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21. Fixation using Alternative Implants for the Treatment of Hip Fractures (FAITH-2): The Exploratory Health-Related Quality of Life and Patient-Reported Functional Outcomes of a Multi-Centre 2 × 2 Factorial Randomized Controlled Pilot Trial in Young Femoral Neck Fracture Patients

Author

Slobogean, Gerard P., primary, Sprague, Sheila, additional, Bzovsky, Sofia, additional, Scott, Taryn, additional, Thabane, Lehana, additional, Heels-Ansdell, Diane, additional, O'Toole, Robert V., additional, Howe, Andrea, additional, Gaski, Greg E., additional, Hill, Lauren C., additional, Brown, Krista M., additional, Viskontas, Darius, additional, Zomar, Mauri, additional, Della Rocca, Gregory J., additional, O'Hara, Nathan N., additional, Bhandari, Mohit, additional, Malekzadeh, A. Stephen, additional, Nauth, Aaron, additional, Perdue, Aaron, additional, Mamun, Abdullah, additional, Wasim, Abeer, additional, Klein, Adam, additional, Brandon, Adrienne, additional, Theriault, Aimee, additional, Garibaldi, Alisha, additional, Liew, Allan, additional, Atrey, Amit, additional, Lialios-Ramfos, Anastasia, additional, Spiguel, André, additional, Howe, Andrea L., additional, Furey, Andrew, additional, Marcantonio, Andrew J., additional, Pollak, Andrew N., additional, Schmidt, Andrew, additional, Dowbenka, Ann, additional, Mak, Anne, additional, Sorkin, Anthony T., additional, Sivananthan, Araby, additional, Buck, Ashley, additional, Okocha, Benita, additional, Frye, Benjamin, additional, Perey, Bertrand, additional, Mohan, Bindu, additional, Eyberg, Blake, additional, Sumner, Bonnie, additional, Fan, Brenda Chen, additional, Lindsey, Brock, additional, Schoonover, Carrie, additional, Schwartzbach, Cary C., additional, Lieder, Charles, additional, Koenig, Chris, additional, Boulton, Christina, additional, LeBrun, Christopher, additional, Jones, Clifford B., additional, Barber, Collin, additional, Donahue, Craig, additional, Ventry, Cyndi, additional, Carter, Cynthia, additional, Williams, Dale, additional, Richardson, Damien, additional, Connelly, Daniel, additional, Mascarenhas, Daniel, additional, Squire, Daniel, additional, Whelan, Daniel, additional, Dias, Danyella, additional, Roffey, Darren M., additional, Hubbard, David, additional, Stephen, David J.G., additional, Shearer, David, additional, Teague, David, additional, Templeman, David, additional, Walmsley, David, additional, Malish, Dean, additional, Sietsema, Debra L., additional, Nam, Diane, additional, Marinos, Dimitrius, additional, Boyer, Dory, additional, McDonough, E. Barry, additional, Bogoch, Earl, additional, Westrick, Edward, additional, Pullenayegum, Eleanor M., additional, Berhaneselase, Eleni, additional, Agustin, Elizabeth, additional, Schemitsch, Emil H., additional, Meinberg, Eric, additional, Baker, Erin, additional, Moola, Farhad, additional, Adamsahib, Fathima, additional, Howells, Fiona, additional, Wells, Garrett, additional, Bal, George K., additional, Reahl, George, additional, Slobogean, Gerard P., additional, Ramonas, Gitana, additional, Guyatt, Gordon, additional, Rocca, Gregory J. Della, additional, Mueller, Gudrun Mirick, additional, Lemke, H. Michael, additional, Kreder, Hans J., additional, Grant, Heather, additional, Ahn, Henry, additional, Broekhuyse, Henry, additional, Leung, Irene, additional, Goulet, James, additional, Waddell, James, additional, Lowe, Jason, additional, Nascone, Jason W., additional, Schulman, Jeff E., additional, Potter, Jeffrey, additional, Hagen, Jennifer, additional, Hidy, Jennifer T., additional, Westberg, Jerald R., additional, Hall, Jeremy A., additional, Burns, Jessica, additional, Peattie, Jessica, additional, Goodwin, Jill, additional, Gagnier, Joel J., additional, France, John, additional, Iazzetta, John, additional, Lubicky, John P., additional, Garfi, John S., additional, Kwong, Johnathan, additional, Walker, Joseph, additional, Hustedt, Joshua, additional, Rudnicki, Joshua, additional, Foxall, Julia, additional, Robbins, Julie, additional, Sadasivan, Kalia, additional, Ryan, Karen, additional, Walsh, Karen, additional, Moon, Karyn, additional, Polihronidis, Katerina, additional, Ordonio, Katherine, additional, Hatzifilalithis, Katrina, additional, Milner, Katrine, additional, Au, Keegan, additional, Apostle, Kelly, additional, Lefaivre, Kelly, additional, Madden, Kim, additional, Swasey, Krystal, additional, Jeray, Kyle, additional, Deeter, Lakye, additional, Fine, Landon, additional, Parsons, Laura, additional, Kempton, Laurence B., additional, Buckingham, Lisa, additional, Sutton, Lisa Giblin, additional, Ramsey, Lolita, additional, Swiontkowski, Marc, additional, Sciadini, Marcus F., additional, Hake, Mark, additional, Richardson, Mark, additional, Nousiainen, Markku, additional, Bernaus, Martí, additional, Heetveld, Martin J., additional, Dietz, Matthew, additional, Menon, Matthew, additional, Patrick, Matthew, additional, MacNevin, Melanie, additional, Johnson, Melissa, additional, Fuerst, Merryjessica, additional, McKee, Michael D., additional, Duran, Michael, additional, Holzman, Michael, additional, Lucero, Michael, additional, Kain, Michael S.H., additional, Bramer, Michelle A., additional, Vogt, Michelle, additional, Vicente, Milena R., additional, Kunz, Monica, additional, Pekmezci, Murat, additional, Harris, Nicole, additional, Simunovic, Nicole, additional, Sultana, Nigar, additional, Dehghan, Niloofar, additional, Clovis, Nina, additional, Chutkan, Norman, additional, Suthar, Paril, additional, Henry, Patrick, additional, Knaus, Paul, additional, Muccino, Paul, additional, Toogood, Paul, additional, Berger, Peter, additional, O'Brien, Peter, additional, Rockwood, Peter, additional, Johnson, Pierce, additional, Guy, Pierre, additional, Blachut, Piotr, additional, Devereaux, PJ, additional, Pritchard (Moon), Raely, additional, Johal, Raman, additional, Tuazon, Ravianne, additional, Pensy, Raymond, additional, Zaidi, Raza, additional, Jenkinson, Richard J., additional, Hymes, Robert A., additional, McCormack, Robert, additional, O'Toole, RobertV., additional, Walker, Robert, additional, Natoli, Roman, additional, Meldrum, Russell, additional, Bicknell, Ryan, additional, DiGiovanni, Ryan, additional, Montalvo, Ryan, additional, Shelhamer, Ryan, additional, Morshed, Saam, additional, McFarland, Sara, additional, Anthony, Sarah, additional, Ward, Sarah, additional, Ahmed, Sarim, additional, Daffner, Scott, additional, Karr, Sean, additional, Mitchell, Sean, additional, Haaser, Sharon, additional, Rye, Sheila, additional, Davis, Sherri, additional, Weir, Sherry, additional, Brisbane, Sonya, additional, Papp, Steven, additional, Beltz, Susan, additional, Liew, Susan, additional, Mauro, Susan, additional, Murphy, T. Ryan, additional, Moore, Tara, additional, Dykes, Taylor, additional, Manson, Theodore, additional, DiPasquale, Thomas, additional, Belaye, Tigist, additional, Daniels, Timothy, additional, Carter, Tina, additional, Oliver, Todd M., additional, McKinley, Todd O., additional, Salopek, Traci, additional, Stone, Trevor, additional, Caron, Troy, additional, Tufescu, Tudor V., additional, Leviton, Tzivia, additional, Keough, Valisha, additional, Jones, Vicki, additional, Eglseder Jr., W. Andrew, additional, Gofton, Wade, additional, Virkus, Walter W., additional, Ghent, Wesley, additional, Degani, Yasmin, additional, Hannaford, Zeta, additional, and Murdoch, Zoe, additional

Published
2021
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23. Implementing stakeholder engagement to explore alternative models of consent: An example from the PREP-IT trials

Author

Pechero, Guillermo, primary, Pfaff, Branden, additional, Rao, Mayank, additional, Pogorzelski, David, additional, McKay, Paula, additional, Spicer, Ella, additional, Howe, Andrea, additional, Demyanovich, Haley K., additional, Sietsema, Debra L., additional, McTague, Michael F., additional, Ramsey, Lolita, additional, Holden, Martha, additional, Rudnicki, Joshua, additional, Wells, Jeff, additional, Medeiros, Michelle, additional, Slobogean, Gerard P., additional, Sprague, Sheila, additional, Wells, Jeffrey, additional, Bhandari, Mohit, additional, O'Toole, Robert V., additional, D'Alleyrand, Jean-Claude, additional, Eglseder, Andrew, additional, Johnson, Aaron, additional, Langhammer, Christopher, additional, Lebrun, Christopher, additional, Manson, Theodore, additional, Nascone, Jason, additional, Paryavi, Ebrahim, additional, Pensy, Raymond, additional, Pollak, Andrew, additional, Sciadini, Marcus, additional, Degani, Yasmin, additional, O'Hara, Nathan N., additional, Joseph, Katherine, additional, Camara, Megan, additional, Harris, Anthony D., additional, Mullins, Daniel C., additional, Thabane, Lehana, additional, Wood, Amber, additional, Della Rocca, Gregory J., additional, Hebden, Joan, additional, Jeray, Kyle J., additional, Marchand, Lucas, additional, O'Hara, Lyndsay M., additional, Zura, Robert, additional, Gardner, Michael J., additional, Blasman, Jenna, additional, Davies, Jonah, additional, Liang, Stephen, additional, Taljaard, Monica, additional, Devereaux, P.J., additional, Guyatt, Gordon H., additional, Heels-Ansdell, Diane, additional, Marvel, Debra, additional, Palmer, Jana, additional, Friedrich, Jeff, additional, Grissom, Ms Frances, additional, Gitajn, I. Leah, additional, Morshed, Saam, additional, Petrisor, Bradley A., additional, Mossuto, Franca, additional, Joshi, Manjari G., additional, Fowler, Justin, additional, Rivera, Jessica, additional, Talbot, Max, additional, Dodds, Shannon, additional, Garibaldi, Alisha, additional, Li, Silvia, additional, Nguyen, Uyen, additional, Rojas, Alejandra, additional, Scott, Taryn, additional, Del Fabbro, Gina, additional, Szasz, Olivia Paige, additional, Demyanovich, Haley, additional, Little, Kelly, additional, Mullins, C. Daniel, additional, Kettering, Eric, additional, Hale, Diamond, additional, Petrisor, Brad A., additional, Johal, Herman, additional, Ristevski, Bill, additional, Williams, Dale, additional, Denkers, Matthew, additional, Rajaratnam, Krishan, additional, Al-Asiri, Jamal, additional, Leonard, Jordan, additional, Marcano-Fernández, Francesc A., additional, Gallant, Jodi, additional, Persico, Federico, additional, Gjorgjievski, Marko, additional, George, Annie, additional, Natoli, Roman M., additional, Gaski, Greg E., additional, McKinley, Todd O., additional, Virkus, Walter W., additional, Sorkin, Anthony T., additional, Szatkowski, Jan P., additional, Baele, Joseph R., additional, Mullis, Brian H., additional, Hill, Lauren C., additional, Hudgins, Andrea, additional, Osborn, Patrick, additional, Pierrie, Sarah, additional, Martinez, Eric, additional, Kimmel, Joseph, additional, Adams, John D., additional, Beckish, Michael L., additional, Bray, Christopher C., additional, Brown, Timothy R., additional, Cross, Andrew W., additional, Dew, Timothy, additional, Faucher, Gregory K., additional, Gurich, Richard W., additional, Lazarus, David E., additional, Millon, S. John, additional, Palmer, M. Jason, additional, Porter, Scott E., additional, Schaller, Thomas M., additional, Sridhar, Michael S., additional, Sanders, John L., additional, Rudisill, L. Edwin, additional, Garitty, Michael J., additional, Poole, Andrew S., additional, Sims, Michael L., additional, Walker, Clark M., additional, Carlisle, Robert M., additional, Hofer, Erin Adams, additional, Huggins, Brandon S., additional, Hunter, Michael D., additional, Marshall, William A., additional, Ray, Shea Bielby, additional, Smith, Cory D., additional, Altman, Kyle M., additional, Bedard, Julia C., additional, Loeffler, Markus F., additional, Pichiotino, Erin R., additional, Cole, Austin A., additional, Maltz, Ethan J., additional, Parker, Wesley, additional, Ramsey, T. Bennett, additional, Burnikel, Alex, additional, Colello, Michael, additional, Stewart, Russell, additional, Wise, Jeremy, additional, Moody, M. Christian, additional, Tanner, Stephanie L., additional, Snider, Rebecca G., additional, Townsend, Christine E., additional, Pham, Kayla H., additional, Martin, Abigail, additional, Robertson, Emily, additional, Miclau, Theodore, additional, Kandemir, Utku, additional, Marmor, Meir, additional, Matityahu, Amir, additional, McClellan, R. Trigg, additional, Meinberg, Eric, additional, Shearer, David, additional, Toogood, Paul, additional, Ding, Anthony, additional, Donohoe, Erin, additional, Murali, Jothi, additional, Belaye, Tigist, additional, Berhaneselase, Eleni, additional, Paul, Alexandra, additional, Garg, Kartik, additional, Gary, Joshua L., additional, Warner, Stephen J., additional, Munz, John W., additional, Choo, Andrew M., additional, Achor, Timothy S., additional, “Chip” Routt, Milton L., additional, Pechero, Guillermo, additional, Miller, Adam, additional, Hagen, Jennifer E., additional, Patrick, Matthew, additional, Vlasak, Richard, additional, Krupko, Thomas, additional, Sadasivan, Kalia, additional, Koenig, Chris, additional, Bailey, Daniel, additional, Wentworth, Daniel, additional, Van, Chi, additional, Schwartz, Justin, additional, Dehghan, Niloofar, additional, Jones, Clifford B., additional, Tracy Watson, J., additional, McKee, Michael, additional, Karim, Ammar, additional, Talerico, Michael, additional, Williams, Alyse, additional, Dykes, Tayler, additional, Obremskey, William T., additional, Jahangir, Amir Alex, additional, Sethi, Manish, additional, Boyce, Robert, additional, Stinner, Daniel J., additional, Mitchell, Phillip, additional, Trochez, Karen, additional, Rodriguez, Andres, additional, Gajari, Vamshi, additional, Rodriguez, Elsa, additional, Pritchett, Charles, additional, Boulton, Christina, additional, Lowe, Jason, additional, Wild, Jason, additional, Ruth, John T., additional, Taylor, Michel, additional, Seach, Andrea, additional, Saeed, Sabina, additional, Culbert, Hunter, additional, Cruz, Alejandro, additional, Knapp, Thomas, additional, Hurkett, Colin, additional, Lowney, Maya, additional, Prayson, Michael, additional, Venkatarayappa, Indresh, additional, Horne, Brandon, additional, Jerele, Jennifer, additional, Clark, Linda, additional, Marcano-Fernández, Francesc, additional, Jornet-Gibert, Montsant, additional, Martínez-Carreres, Laia, additional, Martí-Garín, David, additional, Serrano-Sanz, Jorge, additional, Sánchez-Fernández, Joel, additional, Sanz-Molero, Matsuyama, additional, Carballo, Alejandro, additional, Pelfort, Xavier, additional, Acerboni-Flores, Francesc, additional, Alavedra-Massana, Anna, additional, Anglada-Torres, Neus, additional, Berenguer, Alexandre, additional, Cámara-Cabrera, Jaume, additional, Caparros-García, Ariadna, additional, Fillat-Gomà, Ferran, additional, Fuentes-López, Ruben, additional, Garcia-Rodriguez, Ramona, additional, Gimeno-Calavia, Nuria, additional, Graells-Alonso, Guillem, additional, Martínez-Álvarez, Marta, additional, Martínez-Grau, Patricia, additional, Pellejero-García, Raúl, additional, Ràfols-Perramon, Ona, additional, Peñalver, Juan Manuel, additional, Domènech, Mònica Salomó, additional, Soler-Cano, Albert, additional, Velasco-Barrera, Aldo, additional, Yela-Verdú, Christian, additional, Bueno-Ruiz, Mercedes, additional, Sánchez-Palomino, Estrella, additional, Guerra-Farfan, Ernesto, additional, Tomas-Hernandez, Jordi, additional, Teixidor-Serra, Jordi, additional, Molero-Garcia, Vicente, additional, Selga-Marsa, Jordi, additional, Porcel-Vasquez, Juan Antonio, additional, Andres-Peiro, Jose Vicente, additional, Minguell-Monyart, Joan, additional, Garcia-Sanchez, Yaiza, additional, Nuñez-Camarena, Jorge, additional, Tauste-Rubio, Eladia, additional, Gonzalez-Amigo, Marta, additional, Romeo, Nicholas M., additional, Vallier, Heather A., additional, Breslin, Mary A., additional, Fraifogl, Joanne, additional, Wilson, Eleanor S., additional, Wadenpfuhl, Leanne K., additional, Halliday, Paul G., additional, Viskontas, Darius G., additional, Apostle, Kelly L., additional, Boyer, Dory S., additional, Moola, Farhad O., additional, Perey, Bertrand H., additional, Stone, Trevor B., additional, Lemke, H. Michael, additional, Zomar, Mauri, additional, Fan, Chen “Brenda”, additional, Payne, Kyrsten, additional, Phelps, Kevin, additional, Bosse, Michael, additional, Karunakar, Madhav, additional, Kempton, Laurence, additional, Sims, Stephen, additional, Hsu, Joseph, additional, Seymour, Rachel, additional, Churchill, Christine, additional, Bartel, Claire, additional, Mayberry, Robert Miles, additional, Brownrigg, Maggie, additional, Girardi, Cara, additional, Mayfield, Ada, additional, Hymes, Robert A., additional, Schwartzbach, Cary C., additional, Schulman, Jeff E., additional, Malekzadeh, A. Stephen, additional, Holzman, Michael A., additional, Ahn, James S., additional, Panjshiri, Farhanaz, additional, Das, Sharmistha, additional, English, Antoinisha D., additional, Haaser, Sharon M., additional, Cuff, Jaslynn A.N., additional, Pilson, Holly, additional, Carroll, Eben A., additional, Halvorson, Jason J., additional, Babcock, Sharon, additional, Goodman, J. Brett, additional, Holden, Martha B., additional, Bullard, Debra, additional, Williams, Wendy, additional, Higgins, Thomas F., additional, Haller, Justin M., additional, Rothberg, David L., additional, Marchand, Lucas S., additional, Neese, Ashley, additional, Russell, Mark, additional, Olsen, Zachary M., additional, Coe, Marcus, additional, Dwyer, Kevin, additional, Mullin, Devin S., additional, Reilly, Clifford A., additional, DePalo, Peter, additional, Hall, Amy E., additional, Heng, Marilyn, additional, Harris, Mitchel B., additional, Smith, R. Malcolm, additional, Lhowe, David W., additional, Esposito, John G., additional, Bansal, Mira, additional, Bergin, Patrick F., additional, Russell, George V., additional, Graves, Matthew L., additional, Morellato, John, additional, Champion, Heather K., additional, Johnson, Leslie N., additional, McGee, Sheketha L., additional, Bhanat, Eldrin L., additional, Mehta, Samir, additional, Donegan, Derek, additional, Ahn, Jaimo, additional, Horan, Annamarie, additional, Dooley, Mary, additional, Kuczinski, Ashley, additional, Iwu, Ashley, additional, Potter, David, additional, VanDemark, Robert, additional, Hollinsworth, Troy, additional, Weaver, Michael J., additional, von Keudell, Arvind G., additional, Allen, Elizabeth M., additional, Jaeblon, Todd, additional, Beer, Robert, additional, Gage, Mark J., additional, Reilly, Rachel M., additional, and Sparrow, Cindy, additional

Published
2021
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25. Patient and stakeholder engagement learnings: PREP-IT as a case study

Author

Medeiros, Michelle, primary, Love, T Rosie, additional, Slobogean, Gerard P., additional, Sprague, Sheila, additional, Perfetto, Eleanor M., additional, O'Hara, Nathan N., additional, Mullins, C. Daniel, additional, Wells, Jeffrey, additional, Bhandari, Mohit, additional, D'alleyrand, Jean-Claude, additional, Harris, Anthony, additional, Mullins, Daniel C., additional, Thabane, Lehana, additional, Wood, Amber, additional, Della Rocca, Gregory J., additional, Hebden, Joan, additional, Jeray, Kyle J., additional, Marchand, Lucas, additional, O'Hara, Lyndsay M., additional, Zura, Robert, additional, Gardner, Michael J., additional, Blasman, Jenna, additional, Davies, Jonah, additional, Liang, Stephen, additional, Taljaard, Monica, additional, Devereaux, PJ, additional, Guyatt, Gordon H., additional, Heels-Ansdell, Dianne, additional, Marvel, Debra, additional, Palmer, Jana, additional, Friedrich, Jeff, additional, O'Hara, Nathan, additional, Grissom, Frances, additional, Gitajn, Leah, additional, Morshed, Saam, additional, O'Toole, Robert, additional, Petrisor, Bradley A., additional, Camara, Megan, additional, Mossuto, Franca, additional, Joshi, Manjari G., additional, Fowler, Justin, additional, Rivera, Jessica, additional, Talbot, Max, additional, Dodds, Shannon, additional, Garibaldi, Alisha, additional, Li, Silvia, additional, Nguyen, Uyen, additional, Pogorzelski, David, additional, Rojas, Alejandra, additional, Scott, Taryn, additional, Del Fabbro, Gina, additional, Szasz, Olivia Page, additional, McKay, Paula, additional, Howe, Andrea, additional, Rudnicki, Joshua, additional, Demyanovich, Haley, additional, Little, Kelly, additional, Boissonneault, Adam, additional, Medeiros, Michellic, additional, Kettering, Eric, additional, Hale, Diamond, additional, Mahal, Nirmen, additional, Eglseder, Andrew, additional, Johnson, Aaron, additional, Langhammer, Christopher, additional, Lebrun, Christopher, additional, Manson, Theodore, additional, Nascone, Jason, additional, Paryavi, Ebrahim, additional, Pensy, Raymond, additional, Pollack, Andrew, additional, Sciadini, Marcus, additional, Degani, Yasmin, additional, Joseph, Katherine, additional, S. Marchand, Lucas, additional, Phipps, Heather, additional, Hempen, Eric, additional, Johal, Herman, additional, Risteyski, Bill, additional, Williams, Dale, additional, Denkers, Matthew, additional, Rajaratnam, Krishan, additional, Al-Asiri, Jamal, additional, Leonard, Jordan, additional, Marcano-Fernández, Francesc A., additional, Gallant, Jodi, additional, Persico, Federico, additional, Gjorgjievski, Marko, additional, George, Annie, additional, McGaugh, Sarah M., additional, Pusztai, Kaitlyn, additional, Piekarski, Sarah, additional, Lyons, Mavis, additional, Gennaccaro, Julia, additional, Natoli, Roman M., additional, Gaski, Greg E., additional, McKinley, Todd O., additional, Virkus, Walter W., additional, Sorkin, Anthony T., additional, Szatkowski, Jan P., additional, Baele, Joseph R., additional, Mullis, Brian H., additional, Jang, Yohan, additional, Lopas, Luke A., additional, Hill, Lauren C., additional, Hudgins, Andrea, additional, Fentz, Courteney L., additional, Diaz, Maricela M., additional, Garst, Katelyn M., additional, Denari, Emma W., additional, Osborn, Patrick, additional, Pierrie, Sarah, additional, Martinez, Eric, additional, Kimmel, Joseph, additional, Herrera, Maria, additional, Adams, John D., additional, Beckish, Michael, additional, Bray, Christopher, additional, Brown, Timothy R., additional, Cross, Andrew W., additional, Dew, Timothy, additional, Faucher, Gregory, additional, Gurich Jr, Richard W., additional, Lazarus, David E., additional, Millon, S. John, additional, Palmer, M. Jason, additional, Porter, Scott E., additional, Schaller, Thomas M., additional, Sridhar, Michael S., additional, Sanders, John L., additional, Rudisill Jr, Edwin L., additional, Garitty, Michael J., additional, Poole, Andrew S., additional, Sims, Michael L., additional, Walker, Clark M., additional, Carlisle II, Robert M., additional, Hofer, Erin Adams, additional, Huggins, Brandon S., additional, Hunter, Michael D., additional, Marshall, William A., additional, Ray, Shea Bielby, additional, Smith, Cory D., additional, Altman, Kyle M., additional, Bedard, Julia C., additional, Loeffler, Markus F., additional, Pichiotino, Erin R., additional, Cole, Austin A., additional, Maltz, Ethan J., additional, Parker, Wesley, additional, Ramsey, T. Bennett, additional, Burnikel, Alex, additional, Colello, Michael, additional, Stewart, Russell, additional, Wise, Jeremy, additional, Moody, M. Christian, additional, Anderson, Matthew, additional, Eskew, Joshua, additional, Judkins, Benjamin, additional, Miller, James M., additional, Tanner, Stephanie L., additional, Snider, Rebecca G., additional, Townsend, Christine E., additional, Pham, Kayla H., additional, Martin, Abigail, additional, Robertson, Emily, additional, Wilson Sykes, John, additional, Miclau, Theodore, additional, Kandemir, Utku, additional, Marmor, Meir, additional, Matityahu, Amir, additional, McClellan, R. Trigg, additional, Meinberg, Eric, additional, Shearer, David, additional, Toogood, Paul, additional, Ding, Anthony, additional, Donohue, Erin, additional, Murali, Jothi, additional, El Naga, Ashraf, additional, Tangtiphaiboontana, Jennifer, additional, Belaye, Tigist, additional, Berhaneselase, Eleni, additional, Paul, Alexandra, additional, Garg, Kartik, additional, Pokhvashchev, Dmitry, additional, Gary, Joshua L., additional, Warner, Stephen J., additional, Munz, John W., additional, Choo, Andrew M., additional, Achor, Timothy, additional, Routt, Milton L. "Chip", additional, Rao, Mayank, additional, Pechero, Guillermo, additional, Miller, Adam, additional, Kutzler, Michael, additional, Boutte, Sterling, additional, Warth, Ryan J., additional, Hagen, Jennifer E., additional, Patrick, Matthew, additional, Vlasak, Richard, additional, Krupko, Thomas, additional, Sadasivan, Kalia, additional, Talerico, Michael, additional, Horodyski, Marybeth, additional, Koenig, Chris, additional, Bailey, Daniel, additional, Wentworth, Daniel, additional, Van, Chi, additional, Schwartz, Justin, additional, Pazik, Marissa, additional, Lossada-Soto, Elizabeth, additional, Dehghan, Niloofar, additional, Jones, Clifford B., additional, Watson, J. Tracy, additional, McKee, Michael, additional, Karim, Ammar, additional, Sietsema, Debra L., additional, William, Alyse, additional, Dykes, Tayler, additional, Obremskey, William T., additional, Jahangir, Amir Alex, additional, Sethi, Manish, additional, Boyce, Robert, additional, Stinner, Daniel J., additional, Mitchell, Phillip, additional, Trochez, Karen, additional, Rodriguez, Andres, additional, Gajari, Vamshi, additional, Rodriguez, Elsa, additional, Pritchett, Chris, additional, Hogan, Natalie, additional, Moreno, Fidel A., additional, Boulton, Christina, additional, Lowe, Jason, additional, Wild, Jason, additional, Ruth, John T., additional, Taylor, Michel, additional, Askam, Brad, additional, Seach, Andrea, additional, Saeed, Sabina, additional, Culbert, Hunter, additional, Crus, Alejandro, additional, Knapp, Thomas, additional, Hurkett, Colin, additional, Lowney, Maya, additional, Featherston, Breanna, additional, Carlson, Robin, additional, Romero, Iliana, additional, Zarif, Isaac, additional, Prayson, Michael, additional, Venkatarayappa, Indresh, additional, Horne, Brandon, additional, Jerele, Jennifer, additional, Clark, Linda, additional, Marcano-Fernández, Francesc, additional, Jornet-Gibert, Montsant, additional, Martínez-Carreres, Laia, additional, Martí-Garín, David, additional, Serrano-Sanz, Jorge, additional, Sánchez-Fernández, Joel, additional, Sanz-Molero, Matsuyama, additional, Carballo, Alejandro, additional, Pelfort, Xavier, additional, Acerboni-Flores, Francesc, additional, Alavedra-Massana, Anna, additional, Anglada-Torres, Neus, additional, Berenguer, Alexandre, additional, Cámara-Cabrera, Jaume, additional, Caparros-García, Ariadna, additional, Fillat-Gomà, Ferran, additional, Fuentes-López, Ruben, additional, Garcia-Rodriguez, Ramona, additional, Gimeno-Clavia, Nuria, additional, Graells-Alonso, Guillem, additional, Martínez-álvarez, Marta, additional, Martínez-Grau, Patricia, additional, Pellejero-García, Raúl, additional, Ràfols-Perramon, Ona, additional, Peñalver, Juan Manuel, additional, Salomò Domènech, Mònica, additional, Soler-Cano, Albert, additional, Velasco-Barrera, Aldo, additional, Yela-Verdú, Christian, additional, Bueno-Ruiz, Mercedes, additional, Sánchez-Palomino, Estrella, additional, Andriola, Vito, additional, Molina-Corbacho, Matilde, additional, Maldonado-Sotoca, Yeray, additional, Gasset-Teixidor, Alfons, additional, Blasco-Moreu, Jorge, additional, Fernández-Poch, Núria, additional, Rodoreda-Puigdemasa, Josep, additional, Verdaguer-Figuerola, Arnau, additional, Enrique Cueva-Sevieri, Heber, additional, Garcia-Gimenez, Santiago, additional, Guerra-Farfán, Ernesto, additional, Tomas-Hernandez, Jordi, additional, Teixidor-Serra, Jordi, additional, Molero-Garcia, Vicente, additional, Selga-Marsa, Jordi, additional, Porcel-Vazquez, Juan Antonio, additional, Andres-Peiro, Jose Vicente, additional, Minguell-Monyart, Joan, additional, Nuñez-Camarena, Jorge, additional, del Mar Villar-Casares, Maria, additional, Mestre-Torres, Jaume, additional, Lalueza-Broto, Pilar, additional, Moreira-Borim, Felipe, additional, García, Yaiza, additional, Romeo, Nicholas M., additional, Vallier, Heather A., additional, Breslin, Mary A., additional, Fraifogl, Joanne, additional, Wilson, Eleanor S., additional, Wadenpfuhl, Leanne K, additional, Halliday, Paul G., additional, Heimke, Isabella, additional, Viskontas, Darius G., additional, Apostle, Kelly L., additional, Boyer, Dory S., additional, Moola, Farhad O., additional, Perey, Bertrand H., additional, Stone, Trevor B., additional, Lemke, H. Michael, additional, Zomar, Mauri, additional, Spicer, Ella, additional, Fan, Chen "Brenda", additional, Payne, Kyrsten, additional, Phelps, Kevin, additional, Bosse, Michael, additional, Karunakar, Madhav, additional, Kempton, Laurence, additional, Sims, Stephen, additional, Hsu, Joseph, additional, Seymour, Rachel, additional, Churchill, Christine, additional, Bartel, Claire, additional, Mayberry, Robert Miles, additional, Brownrigg, Maggie, additional, Girardi, Cara, additional, Mayfield, Ada, additional, Sweeney, Juliette, additional, Pollock, Hannah, additional, Hymes, Robert A., additional, Schwartzbach, Cary C., additional, Schulman, Jeff E., additional, Malekzadeh, A. Stephen, additional, Holzman, Michael A., additional, Wills, Jonathan, additional, Ramsey, Lolita, additional, Ahn, James S., additional, Panjshiri, Farhanaz, additional, Das, Sharmistha, additional, English, Antoinisha D., additional, Haaser, Sharon M., additional, Cuff, Jaslynn A.N., additional, Pilson, Holly, additional, Carroll, Eben A., additional, Halvorson, Jason J., additional, Babcock, Sharon, additional, Goodman, J. Brett, additional, Holden, Martha B., additional, Bullard, Debra, additional, Williams, Wendy, additional, Hill, Taylor, additional, Brotherton, Ariel, additional, Higgins, Thomas F., additional, Haller, Justin M., additional, Rothberg, David L., additional, Neese, Ashley, additional, Russell, Mark, additional, Olsen, Zachary M., additional, McGowan, Abby V., additional, Hill, Sophia, additional, Coe, Marcus, additional, Dwyer, Kevin, additional, Mullin, Devin S., additional, Reily, Clifford A, additional, DePalo, Peter, additional, Hall, Amy E., additional, Dabrowski, Rebecca E., additional, Chockbengboun, Theresa A., additional, Heng, Marilyn, additional, Harris, Mitchel B., additional, Smith, R. Malcolm, additional, Lhowe, David W., additional, Esposito, John, additional, Bansal, Mira, additional, McTague, Michael, additional, Alnasser, Ahmad, additional, Bergin, Patrick F., additional, Russell, George V., additional, Graves, Matthew L., additional, Morellato, John, additional, Champion, Heather K., additional, Johnson, Leslie N., additional, McGee, Skeketha L., additional, Bhanat, Eldrin L., additional, Thimothee, Josny, additional, Serrano, Jackie, additional, Mehta, Samir, additional, Donegan, Derek, additional, Ahn, Jaimo, additional, Horan, Annamarie, additional, Dooley, Mary, additional, Kuczinski, Ashley, additional, Iwu, Ashley, additional, Potter, David, additional, VanDemark II, Robert, additional, Pfaff, Branden, additional, Hollinsworth, Troy, additional, Atkins, Kristi, additional, Weaver, Michael J., additional, von Keudel, Arvind G., additional, McTague, Michael F., additional, Allen, Elizabeth M., additional, Sagona, Abigail E., additional, Jaeblon, Todd, additional, Beer, Robert, additional, Bauer, Brent, additional, Meredith, Sean, additional, Stone, Autumn, additional, Gage, Mark J., additional, Reilly, Rachel M., additional, Sparrow, Cindy, additional, Paniagua, Ariana, additional, Domes, Christopher M., additional, Johnson, Kristina P., additional, Shannon, Steven F., additional, Scott, Alesha N., additional, Clinch, Bobbi, additional, Lin, Carol A., additional, Vrahas, Mark S., additional, Moon, Charles N., additional, Marecek, Geoffrey S., additional, Dubuclet, Denice, additional, Scolaro, John A., additional, Learned, James R., additional, Lim, Philip K., additional, Demas, Susan, additional, Beltran, Michael J., additional, Archdeacon, Michael T., additional, Claude Sagi, Henry, additional, Wyrick, John D., additional, Toan Le, Theodore, additional, Laughlin, Richard T., additional, and Thomson, Cameron G., additional

Published
2021
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26. Managing work flow in high enrolling trials: The development and implementation of a sampling strategy in the PREPARE trial

Author

Pogorzelski, David, primary, Nguyen, Uyen, additional, McKay, Paula, additional, Thabane, Lehana, additional, Camara, Megan, additional, Ramsey, Lolita, additional, Seymour, Rachel, additional, Goodman, J. Brett, additional, McGee, Sheketha, additional, Fraifogl, Joanne, additional, Hudgins, Andrea, additional, Tanner, Stephanie L., additional, Bhandari, Mohit, additional, Slobogean, Gerard P., additional, Sprague, Sheila, additional, Wells, Jeffrey, additional, D'Alleyrand, Jean-Claude, additional, Harris, Anthony D., additional, Mullins, Daniel C., additional, Wood, Amber, additional, Della Rocca, Gregory J., additional, Hebden, Joan, additional, Jeray, Kyle J., additional, Marchand, Lucas, additional, O'Hara, Lyndsay M., additional, Zura, Robert, additional, Gardner, Michael J., additional, Blasman, Jenna, additional, Davies, Jonah, additional, Liang, Stephen, additional, Taljaard, Monica, additional, Devereaux, P.J., additional, Guyatt, Gordon H., additional, Heels-Ansdell, Diane, additional, Marvel, Debra, additional, Palmer, Jana, additional, Friedrich, Jeff, additional, O'Hara, Nathan N., additional, Grissom, Ms. Frances, additional, Gitajn, I. Leah, additional, Morshed, Saam, additional, O'Toole, Robert V., additional, Petrisor, Bradley A., additional, Mossuto, Franca, additional, Joshi, Manjari G., additional, Fowler, Justin, additional, Rivera, Jessica, additional, Talbot, Max, additional, Dodds, Shannon, additional, Garibaldi, Alisha, additional, Li, Silvia, additional, Pogorzelski, David, additional, Rojas, Alejandra, additional, Scott, Taryn, additional, Del Fabbro, Gina, additional, Szasz, Olivia Paige, additional, Howe, Andrea, additional, Rudnicki, Joshua, additional, Demyanovich, Haley, additional, Little, Kelly, additional, Mullins, C. Daniel, additional, Medeiros, Michelle, additional, Kettering, Eric, additional, Hale, Diamond, additional, Eglseder, Andrew, additional, Johnson, Aaron, additional, Langhammer, Christopher, additional, Lebrun, Christopher, additional, Manson, Theodore, additional, Nascone, Jason, additional, Paryavi, Ebrahim, additional, Pensy, Raymond, additional, Pollak, Andrew, additional, Sciadini, Marcus, additional, Degani, Yasmin, additional, Demyanovich, Haley K., additional, Joseph, Katherine, additional, Petrisor, Brad A., additional, Johal, Herman, additional, Ristevski, Bill, additional, Williams, Dale, additional, Denkers, Matthew, additional, Rajaratnam, Krishan, additional, Al-Asiri, Jamal, additional, Leonard, Jordan, additional, Marcano-Fernández, Francesc A., additional, Gallant, Jodi, additional, Persico, Federico, additional, Gjorgjievski, Marko, additional, George, Annie, additional, Natoli, Roman M., additional, Gaski, Greg E., additional, McKinley, Todd O., additional, Virkus, Walter W., additional, Sorkin, Anthony T., additional, Szatkowski, Jan P., additional, Baele, Joseph R., additional, Mullis, Brian H., additional, Hill, Lauren C., additional, Osborn, Patrick, additional, Pierrie, Sarah, additional, Martinez, Eric, additional, Kimmel, Joseph, additional, Adams, John D., additional, Beckish, Michael L., additional, Bray, Christopher C., additional, Brown, Timothy R., additional, Cross, Andrew W., additional, Dew, Timothy, additional, Faucher, Gregory K., additional, Gurich, Richard W., additional, Lazarus, David E., additional, Millon, S. John, additional, Palmer, M. Jason, additional, Porter, Scott E., additional, Schaller, Thomas M., additional, Sridhar, Michael S., additional, Sanders, John L., additional, Rudisill, L. Edwin, additional, Garitty, Michael J., additional, Poole, Andrew S., additional, Sims, Michael L., additional, Walker, Clark M., additional, Carlisle, Robert M., additional, Hofer, Erin Adams, additional, Huggins, Brandon S., additional, Hunter, Michael D., additional, Marshall, William A., additional, Ray, Shea Bielby, additional, Smith, Cory D., additional, Altman, Kyle M., additional, Bedard, Julia C., additional, Loeffler, Markus F., additional, Pichiotino, Erin R., additional, Cole, Austin A., additional, Maltz, Ethan J., additional, Parker, Wesley, additional, Ramsey, T. Bennett, additional, Burnikel, Alex, additional, Colello, Michael, additional, Stewart, Russell, additional, Wise, Jeremy, additional, Moody, M. Christian, additional, Snider, Rebecca G., additional, Townsend, Christine E., additional, Pham, Kayla H., additional, Martin, Abigail, additional, Robertson, Emily, additional, Miclau, Theodore, additional, Kandemir, Utku, additional, Marmor, Meir, additional, Matityahu, Amir, additional, McClellan, R. Trigg, additional, Meinberg, Eric, additional, Shearer, David, additional, Toogood, Paul, additional, Ding, Anthony, additional, Donohue, Erin, additional, Belaye, Tigist, additional, Berhaneselase, Eleni, additional, Paul, Alexandra, additional, Garg, Kartik, additional, Gary, Joshua L., additional, Warner, Stephen J., additional, Munz, John W., additional, Choo, Andrew M., additional, Achor, Timothy S., additional, “Chip” Routt, Milton L., additional, Rao, Mayank, additional, Pechero, Guillermo, additional, Miller, Adam, additional, Hagen, Jennifer E., additional, Patrick, Matthew, additional, Vlasak, Richard, additional, Krupko, Thomas, additional, Sadasivan, Kalia, additional, Koenig, Chris, additional, Bailey, Daniel, additional, Wentworth, Daniel, additional, Van, Chi, additional, Schwartz, Justin, additional, Dehghan, Niloofar, additional, Jones, Clifford B., additional, Watson, J Tracy, additional, McKee, Michael, additional, Karim, Ammar, additional, Talerico, Michael, additional, Sietsema, Debra L., additional, Williams, Alyse, additional, Dykes, Tayler, additional, Obremskey, William T., additional, Jahangir, Amir Alex, additional, Sethi, Manish, additional, Boyce, Robert, additional, Stinner, Daniel J., additional, Mitchell, Phillip, additional, Trochez, Karen, additional, Rodriguez, Andres, additional, Gajari, Vamshi, additional, Rodriguez, Elsa, additional, Pritchett, Charles, additional, Boulton, Christina, additional, Lowe, Jason, additional, Wild, Jason, additional, Ruth, John T., additional, Taylor, Michel, additional, Seach, Andrea, additional, Saeed, Sabina, additional, Culbert, Hunter, additional, Cruz, Alejandro, additional, Knapp, Thomas, additional, Hurkett, Colin, additional, Lowney, Maya, additional, Prayson, Michael, additional, Venkatarayappa, Indresh, additional, Horne, Brandon, additional, Jerele, Jennifer, additional, Clark, Linda, additional, Marcano-Fernández, Francesc, additional, Jornet-Gibert, Montsant, additional, Martínez-Carreres, Laia, additional, Martí-Garín, David, additional, Serrano-Sanz, Jorge, additional, Sánchez-Fernández, Joel, additional, Sanz-Molero, Matsuyama, additional, Carballo, Alejandro, additional, Pelfort, Xavier, additional, Acerboni-Flores, Francesc, additional, Alavedra-Massana, Anna, additional, Anglada-Torres, Neus, additional, Berenguer, Alexandre, additional, Cámara-Cabrera, Jaume, additional, Caparros-García, Ariadna, additional, Fillat-Gomà, Ferran, additional, Fuentes-López, Ruben, additional, Garcia-Rodriguez, Ramona, additional, Gimeno-Calavia, Nuria, additional, Graells-Alonso, Guillem, additional, Martínez-Álvarez, Marta, additional, Martínez-Grau, Patricia, additional, Pellejero-García, Raúl, additional, Ràfols-Perramon, Ona, additional, Peñalver, Juan Manuel, additional, Domènech, Mònica Salomó, additional, Soler-Cano, Albert, additional, Velasco-Barrera, Aldo, additional, Yela-Verdú, Christian, additional, Bueno-Ruiz, Mercedes, additional, Sánchez-Palomino, Estrella, additional, Guerra, Ernesto, additional, García, Yaiza, additional, Romeo, Nicholas M., additional, Vallier, Heather A., additional, Breslin, Mary A., additional, Wilson, Eleanor S., additional, Wadenpfuhl, Leanne K., additional, Halliday, Paul G., additional, Viskontas, Darius G., additional, Apostle, Kelly L., additional, Boyer, Dory S., additional, Moola, Farhad O., additional, Perey, Bertrand H., additional, Stone, Trevor B., additional, Lemke, H. Michael, additional, Zomar, Mauri, additional, Spicer, Ella, additional, Fan, Chen “Brenda”, additional, Payne, Kyrsten, additional, Phelps, Kevin, additional, Bosse, Michael, additional, Karunakar, Madhav, additional, Kempton, Laurence, additional, Sims, Stephen, additional, Hsu, Joseph, additional, Churchill, Christine, additional, Bartel, Claire, additional, Mayberry, Robert Miles, additional, Brownrigg, Maggie, additional, Girardi, Cara, additional, Mayfield, Ada, additional, Hymes, Robert A., additional, Schwartzbach, Cary C., additional, Schulman, Jeff E., additional, Malekzadeh, A. Stephen, additional, Holzman, Michael A., additional, Ahn, James S., additional, Panjshiri, Farhanaz, additional, Das, Sharmistha, additional, English, Antoinisha D., additional, Haaser, Sharon M., additional, Cuff, Jaslynn A.N., additional, Pilson, Holly, additional, Carroll, Eben A., additional, Halvorson, Jason J., additional, Babcock, Sharon, additional, Holden, Martha B., additional, Bullard, Debra, additional, Williams, Wendy, additional, Higgins, Thomas F., additional, Haller, Justin M., additional, Rothberg, David L., additional, Neese, Ashley, additional, Russell, Mark, additional, Coe, Marcus, additional, Dwyer, Kevin, additional, Mullin, Devin S., additional, Reilly, Clifford A., additional, DePalo, Peter, additional, Hall, Amy E., additional, Heng, Marilyn, additional, Harris, Mitchel B., additional, Smith, R. Malcolm, additional, Lhowe, David W., additional, Esposito, John G., additional, Bansal, Mira, additional, Bergin, Patrick F., additional, Russell, George V., additional, Graves, Matthew L., additional, Morellato, John, additional, Champion, Heather K., additional, Johnson, Leslie N., additional, McGee, Sheketha L., additional, Bhanat, Eldrin L., additional, Mehta, Samir, additional, Donegan, Derek, additional, Ahn, Jaimo, additional, Horan, Annamarie, additional, Dooley, Mary, additional, Kuczinski, Ashley, additional, Iwu, Ashley, additional, Potter, David, additional, VanDemark, Robert, additional, Pfaff, Branden, additional, Hollinsworth, Troy, additional, Weaver, Michael J., additional, von Keudell, Arvind G., additional, McTague, Michael F., additional, Allen, Elizabeth M., additional, Jaeblon, Todd, additional, Beer, Robert, additional, Gage, Mark J., additional, Reilly, Rachel M., additional, and Sparrow, Cindy, additional

Published
2021
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28. Engaging patients as partners in a multicentre trial of spinal versus general anaesthesia for older adults

Author

Hruslinski, Jennifer, primary, Menio, Diane A., additional, Hymes, Robert A., additional, Jaffe, J. Douglas, additional, Langlois, Christine, additional, Ramsey, Lolita, additional, Gaskins, Lakisha J., additional, Neuman, Mark D., additional, Looke, Thomas, additional, Bent, Sandra, additional, Franco-Mora, Ariana, additional, Hedrick, Pamela, additional, Newbern, Matthew, additional, Tadros, Rafik, additional, Pealer, Karen, additional, Marcantonio, Edward, additional, Vlassakov, Kamen, additional, Buckley, Carolyn, additional, Gorbatov, Svetlana, additional, Gosnell, James, additional, Steen, Talora, additional, Vafai, Avery, additional, Zeballos, Jose, additional, Cardenas, Louis, additional, Berry, Ashley, additional, Getchell, John, additional, Quercetti, Nicholas, additional, Sessler, Daniel I., additional, Ayad, Sabry, additional, Hassan, Manal, additional, Ali, Assad, additional, Bajracharya, Gauasan, additional, Billow, Damien, additional, Bloomfield, Michael, additional, Elliott, Kavita, additional, Hampton, Robert, additional, He, Linda, additional, Honar, Hooman, additional, Khoshknabi, Dilara, additional, Kim, Daniel, additional, Minko, Paul, additional, Morris, Adam, additional, Niazi, Azfar, additional, Nutcharoen, Tara, additional, Roberts, Jeffrey, additional, Saha, Partha, additional, Salih, Ahmed, additional, Skolaris, Alexis, additional, Stang, Taylor, additional, Strimbu, Victor, additional, Templeton, Jesse, additional, Volio, Andrew, additional, Wang, Jiayi, additional, Bolkus, Kelly, additional, DeAngelis, Matthew, additional, Dodson, Gregory, additional, Gerritsen, Jeffrey, additional, McEniry, Brian, additional, Mitrev, Ludmil, additional, Kwofie, Kwesi, additional, Bonazza, Flynn, additional, Lloyd, Vera, additional, Panek, Izabela, additional, Dabiri, Jared, additional, Chavez, Chris, additional, Craig, Jason, additional, Davidson, Todd, additional, Dietrichs, Chad, additional, Fleetwood, Cheryl, additional, Foley, Mike, additional, Getto, Chris, additional, Hailes, Susie, additional, Hermes, Sarah, additional, Hooper, Andy, additional, Koener, Greg, additional, Kohls, Kate, additional, Law, Leslie, additional, Lipp, Adam, additional, Losey, Allison, additional, Nelson, William, additional, Nieto, Mario, additional, Rogers, Pam, additional, Rutman, Steve, additional, Scales, Garrett, additional, Sebastian, Barbara, additional, Stanciu, Tom, additional, Lobel, Gregg, additional, Giampiccolo, Michelle, additional, Herman, Dara, additional, Kaufman, Margit, additional, Murphy, Bryan, additional, Pau, Clara, additional, Puzio, Thomas, additional, Veselsky, Marlene, additional, Stone, Trevor, additional, Apostle, Kelly, additional, Boyer, Dory, additional, Fan, Brenda Chen, additional, Lee, Susan, additional, Lemke, Mike, additional, Merchant, Richard, additional, Moola, Farhad, additional, Payne, Kyrsten, additional, Perey, Bertrand, additional, Viskontas, Darius, additional, Poler, Mark, additional, D'Antonio, Patricia, additional, Sheppard, Richard, additional, Abdullah, Amer, additional, Fish-Fuhrmann, Jamie, additional, Giska, Mark, additional, Fidkowski, Christina, additional, Guthrie, Trent, additional, Hakeos, William, additional, Hayes, Lillian, additional, Hoegler, Joseph, additional, Nowak, Katherine, additional, Hymes, Robert, additional, Beck, Jeffery, additional, Cuff, Jaslynn, additional, Gaski, Greg, additional, Haaser, Sharon, additional, Holzman, Michael, additional, Malekzadeh, A. Stephen, additional, Schulman, Jeff, additional, Schwartzbach, Cary, additional, Sieber, Frederick, additional, Azefor, Tangwan, additional, Brown, Charles, additional, Davani, Arman, additional, Jaberi, Mahmood, additional, Masear, Courtney, additional, Sharma, Balram, additional, Haider, Syed Basit, additional, Chungu, Carolyn, additional, Ebrahimi, Ali, additional, Fikry, Karim, additional, Gannon, Kerri, additional, Marcantonio, Andrew, additional, Pace, Meredith, additional, Sanders, David, additional, Clarke, Collin, additional, Lawendy, Abdel, additional, Schwartz, Gary, additional, Garg, Mohit, additional, Kim, Joseph, additional, Marshall, Mitchell, additional, Caurci, Juan, additional, Commeh, Ekow, additional, Cuevas, Randy, additional, Cuff, Germaine, additional, Franco, Lola, additional, Furguiele, David, additional, Giuca, Matthew, additional, Allman, Melissa, additional, Barzideh, Omid, additional, Cossaro, James, additional, D'Arduini, Armando, additional, Farhi, Anita, additional, Gould, Jason, additional, Kafel, John, additional, Patel, Anuj, additional, Peller, Abraham, additional, Reshef, Hadas, additional, Safur, Mohammed, additional, Toscano, Fiore, additional, Tedore, Tiffany, additional, Akerman, Michael, additional, Brumberger, Eric, additional, Clark, Sunday, additional, Friedlander, Rachel, additional, Jegarl, Anita, additional, Lane, Joseph, additional, Lyden, John P., additional, Mehta, Nili, additional, Murrell, Matthew T., additional, Painter, Nathan, additional, Ricci, William, additional, Sbrollini, Kaitlyn, additional, Sharma, Rahul, additional, Steel, Peter A.D., additional, Steinkamp, Michele, additional, Weinberg, Roniel, additional, Wellman, David Stephenson, additional, Nader, Antoun, additional, Fitzgerald, Paul, additional, Ritz, Michaela, additional, Papp, Steven, additional, Bryson, Greg, additional, Craig, Alexandra, additional, Farhat, Cassandra, additional, Gammon, Braden, additional, Gofton, Wade, additional, Harris, Nicole, additional, Lalonde, Karl, additional, Liew, Allan, additional, Meulenkamp, Bradley, additional, Sonnenburg, Kendra, additional, Wai, Eugene, additional, Wilkin, Geoffrey, additional, Donegan, Derek, additional, Dinh, Cassandra, additional, Elkassabany, Nabil, additional, Horan, Annamarie, additional, Mehta, Samir, additional, Troxell, Karen, additional, Alderfer, Mary Ellen, additional, Brannen, Jason, additional, Cupitt, Christopher, additional, Gerhart, Stacy, additional, McLin, Renee, additional, Sheidy, Julie, additional, Yurick, Katherine, additional, Carson, Jeffrey, additional, Chen, Fei, additional, Dragert, Karen, additional, Kiss, Geza, additional, Malveaux, Halina, additional, McCloskey, Deborah, additional, Mellender, Scott, additional, Mungekar, Sagar S., additional, Noveck, Helaine, additional, Sagebien, Carlos, additional, Perlman, Barry, additional, Biby, Luat, additional, McKelvy, Gail, additional, Richards, Anna, additional, Azim, Syed, additional, Abola, Ramon, additional, Ayala, Brittney, additional, Halper, Darcy, additional, Mavarez, Ana, additional, Choi, Stephen, additional, Awad, Imad, additional, Flynn, Brendan, additional, Henry, Patrick, additional, Jenkinson, Richard, additional, Kaustov, Lilia, additional, Lappin, Elizabeth, additional, McHardy, Paul, additional, Singh, Amara, additional, Hauck, Ellen, additional, Donnelly, Joanne, additional, Gonzalez, Meera, additional, Haydel, Christopher, additional, Livelsberger, Jon, additional, Pazionis, Theresa, additional, Slattery, Bridget, additional, Vazquez-Trejo, Maritza, additional, Schwenk, Eric, additional, Baratta, Jaime, additional, Deiling, Brittany, additional, Deschamps, Laura, additional, Glick, Michael, additional, Katz, Daniel, additional, Krieg, James, additional, Lessin, Jennifer, additional, Torjman, Marc, additional, Chin, Ki Jinn, additional, Jin, Rongyu, additional, Salpeter, Mary Jane, additional, Powell, Mark, additional, Simmons, Jeffrey, additional, Lawson, Prentiss, additional, Kukreja, Promil, additional, Graves, Shanna, additional, Sturdivant, Adam, additional, Bryant, Ayesha, additional, Crump, Sandra Joyce, additional, Dillane, Derek, additional, Taylor, Michael, additional, Verrier, Michelle, additional, Applegate, Richard, additional, Arias, Ana, additional, Pineiro, Natasha, additional, Uppington, Jeffrey, additional, Wolinsky, Phillip, additional, Sappenfield, Joshua, additional, Gunnett, Amy, additional, Hagen, Jennifer, additional, Harris, Sara, additional, Hollen, Kevin, additional, Holloway, Brian, additional, Horodyski, Mary Beth, additional, Pogue, Trevor, additional, Ramani, Ramachandran, additional, Smith, Cameron, additional, Woods, Anna, additional, Warrick, Matthew, additional, Flynn, Kelly, additional, Mongan, Paul, additional, Ranganath, Yatish, additional, Fernholz, Sean, additional, Ingersoll-Weng, Esperanza, additional, Marian, Anil, additional, Seering, Melinda, additional, Sibenaller, Zita, additional, Stout, Lori, additional, Wagner, Allison, additional, Walter, Alicia, additional, Wong, Cynthia, additional, Magaziner, Jay, additional, Orwig, Denise, additional, Brown, Trina, additional, Dattilo, Jim, additional, Ellenberg, Susan, additional, Feng, Rui, additional, Fleisher, Lee, additional, Gaskins, Lakisha, additional, Goud, Maithri, additional, Helker, Chris, additional, Mezenghie, Lydia, additional, Montgomery, Brittany, additional, Preston, Peter, additional, Stephens, Alisa, additional, Schwartz, J. Sanford, additional, Tierney, Ann, additional, Weber, Ramona, additional, Chelly, Jacques, additional, Goel, Shiv, additional, Goncz, Wende, additional, Kawabe, Touichi, additional, Khetarpal, Sharad, additional, King, Kevin, additional, Kunkel, Frank, additional, Luke, Charles, additional, Monroe, Amy, additional, Shick, Vladislav, additional, Silipo, Anthony, additional, Stehle, Caroline, additional, Szabo, Katherine, additional, Yennam, Sudhakar, additional, Hoeft, Mark, additional, Breidenstein, Max, additional, Dominick, Timothy, additional, Friend, Alexander, additional, Mathews, Donald, additional, Lennertz, Richard, additional, Akere, Helen, additional, Balweg, Tyler, additional, Bo, Amber, additional, Doro, Christopher, additional, Goodspeed, David, additional, Lang, Gerald, additional, Parker, Maggie, additional, Rettammel, Amy, additional, Roth, Mary, additional, Sanders, Robert, additional, White, Marissa, additional, Whiting, Paul, additional, Allen, Brian, additional, Baker, Tracie, additional, Craven, Debra, additional, McEvoy, Matt, additional, Turnbo, Teresa, additional, Kates, Stephen, additional, Morgan, Melanie, additional, Willoughby, Teresa, additional, Weigel, Wade, additional, Auyong, David, additional, Fox, Ellie, additional, Welsh, Tina, additional, Cusson, Bruce, additional, Dobson, Sean, additional, Edwards, Christopher, additional, Harris, Lynette, additional, Henshaw, Daryl, additional, Johnson, Kathleen, additional, McKinney, Glen, additional, Miller, Scott, additional, Reynolds, Jon, additional, Turner, Jimmy, additional, VanEenenaam, David, additional, Weller, Robert, additional, Akhtar, Shamsuddin, additional, Blessing, Marcelle, additional, Johnson, Chanel, additional, Kampp, Michael, additional, Kunze, Kimberly, additional, Li, Jinlei, additional, O'Connor, Mary, additional, and Treggiari, Miriam, additional

Published
2021
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32. Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures: A Randomized Clinical Trial

Author

O’Toole, Robert V., Joshi, Manjari, Carlini, Anthony R., Murray, Clinton K., Allen, Lauren E., Huang, Yanjie, Scharfstein, Daniel O., O’Hara, Nathan N., Gary, Joshua L., Bosse, Michael J., Castillo, Renan C., Bishop, Julius A., Weaver, Michael J., Firoozabadi, Reza, Hsu, Joseph R., Karunakar, Madhav A., Seymour, Rachel B., Sims, Stephen H., Churchill, Christine, Brennan, Michael L., Gonzales, Gabriela, Reilly, Rachel M., Zura, Robert D., Howes, Cameron R., Mir, Hassan R., Wagstrom, Emily A., Westberg, Jerald, Gaski, Greg E., Kempton, Laurence B., Natoli, Roman M., Sorkin, Anthony T., Virkus, Walter W., Hill, Lauren C., Hymes, Robert A., Holzman, Michael, Malekzadeh, A. Stephen, Schulman, Jeff E., Ramsey, Lolita, Cuff, Jaslynn A. N., Haaser, Sharon, Osgood, Greg M., Shafiq, Babar, Laljani, Vaishali, Lee, Olivia C., Krause, Peter C., Rowe, Cara J., Hilliard, Colette L., Morandi, Massimo Max, Mullins, Angela, Achor, Timothy S., Choo, Andrew M., Munz, John W., Boutte, Sterling J., Vallier, Heather A., Breslin, Mary A., Frisch, H. Michael, Kaufman, Adam M., Large, Thomas M., LeCroy, C. Michael, Riggsbee, Christina, Smith, Christopher S., Crickard, Colin V., Phieffer, Laura S., Sheridan, Elizabeth, Jones, Clifford B., Sietsema, Debra L., Reid, J. Spence, Ringenbach, Kathy, Hayda, Roman, Evans, Andrew R., Crisco, M.J., Rivera, Jessica C., Osborn, Patrick M., Kimmel, Joseph, Stawicki, Stanislaw P., Nwachuku, Chinenye O., Wojda, Thomas R., Rehman, Saqib, Donnelly, Joanne M., Caroom, Cyrus, Jenkins, Mark D., Boulton, Christina L., Costales, Timothy G., LeBrun, Christopher T., Manson, Theodore T., Mascarenhas, Daniel C., Nascone, Jason W., Pollak, Andrew N., Sciadini, Marcus F., Slobogean, Gerard P., Berger, Peter Z., Connelly, Daniel W., Degani, Yasmin, Howe, Andrea L., Marinos, Dimitrius P., Montalvo, Ryan N., Reahl, G. Bradley, Schoonover, Carrie D., Schroder, Lisa K., Vang, Sandy, Bergin, Patrick F., Graves, Matt L., Russell, George V., Spitler, Clay A., Hydrick, Josie M., Teague, David, Ertl, William, Hickerson, Lindsay E., Moloney, Gele B., Weinlein, John C., Zelle, Boris A., Agarwal, Animesh, Karia, Ravi A., Sathy, Ashoke K., Au, Brigham, Maroto, Medardo, Sanders, Drew, Higgins, Thomas F., Haller, Justin M., Rothberg, David L., Weiss, David B., Yarboro, Seth R., McVey, Eric D., Lester-Ballard, Veronica, Goodspeed, David, Lang, Gerald J., Whiting, Paul S., Siy, Alexander B., Obremskey, William T., Jahangir, A. Alex, Attum, Basem, Burgos, Eduardo J., Molina, Cesar S., Rodriguez-Buitrago, Andres, Gajari, Vamshi, Trochez, Karen M., Halvorson, Jason J., Miller, Anna N., Goodman, James Brett, Holden, Martha B., McAndrew, Christopher M., Gardner, Michael J., Ricci, William M., Spraggs-Hughes, Amanda, Collins, Susan C., Taylor, Tara J., and Zadnik, Mary

Abstract

IMPORTANCE: Despite the widespread use of systemic antibiotics to prevent infections in surgically treated patients with fracture, high rates of surgical site infection persist. OBJECTIVE: To examine the effect of intrawound vancomycin powder in reducing deep surgical site infections. DESIGN, SETTING, AND PARTICIPANTS: This open-label randomized clinical trial enrolled adult patients with an operatively treated tibial plateau or pilon fracture who met the criteria for a high risk of infection from January 1, 2015, through June 30, 2017, with 12 months of follow-up (final follow-up assessments completed in April 2018) at 36 US trauma centers. INTERVENTIONS: A standard infection prevention protocol with (n = 481) or without (n = 499) 1000 mg of intrawound vancomycin powder. MAIN OUTCOMES AND MEASURES: The primary outcome was a deep surgical site infection within 182 days of definitive fracture fixation. A post hoc comparison assessed the treatment effect on gram-positive and gram-negative-only infections. Other secondary outcomes included superficial surgical site infection, nonunion, and wound dehiscence. RESULTS: The analysis included 980 patients (mean [SD] age, 45.7 [13.7] years; 617 [63.0%] male) with 91% of the expected person-time of follow-up for the primary outcome. Within 182 days, deep surgical site infection was observed in 29 of 481 patients in the treatment group and 46 of 499 patients in the control group. The time-to-event estimated probability of deep infection by 182 days was 6.4% in the treatment group and 9.8% in the control group (risk difference, –3.4%; 95% CI, –6.9% to 0.1%; P = .06). A post hoc analysis of the effect of treatment on gram-positive (risk difference, –3.7%; 95% CI, –6.7% to –0.8%; P = .02) and gram-negative-only (risk difference, 0.3%; 95% CI, –1.6% to 2.1%; P = .78) infections found that the effect of vancomycin powder was a result of its reduction in gram-positive infections. CONCLUSIONS AND RELEVANCE: Among patients with operatively treated tibial articular fractures at a high risk of infection, intrawound vancomycin powder at the time of definitive fracture fixation reduced the risk of a gram-positive deep surgical site infection, consistent with the activity of vancomycin. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT02227446

Published
2021
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33. Screening for Chlamydial Infection.

Author

LIN, KENNETH W. and RAMSEY, LOLITA

Subjects
CHLAMYDIA infection diagnosis, BACTERIAL diseases
Abstract

A quiz about the diagnosis for chlamydial infection is presented.

Published
2008

34. Impact of Anesthesia selection on Post-Op Pain Management in Operatively treated Hip Fractures.

Author

Davis, Jana M, Cuadra, Mario, Roomian, Tamar, Wally, Meghan K, Seymour, Rachel B, Hymes, Robert A, Ramsey, Lolita, and Hsu, Joseph R

Subjects
*PAIN management, *HIP fractures, *ANALGESIA, *NERVE block, *ANESTHESIA, *GENERAL anesthesia
Abstract

To determine if the use of Peripheral Nerve Block (PNB) versus Local Infiltration Analgesia (LIA) for hip fracture patients, affected opioid consumption in the early post-operative period. Retrospective cohort study Two level 1 trauma centers 588 patients with surgically treated AO/OTA 31A and 31B fractures between February 2016-October 2017 were included. 415 (70.6%) received general anesthesia (GA) alone, 152 received GA plus perioperative PNB (25.9%), and 21 had GA plus LIA intra-operatively (3.6%). Median age was 82 years; predominantly female (67%) and AO/OTA 31A fractures (55.37%). Morphine Milligram Equivalents (MME) at 24 and 48 hours postoperatively, length of stay (LOS) and the occurrence of any complication after surgery The PNB cohort was less likely to use any opioid than the GA group at 24 and 48 hours postoperatively (OR: 0.36, 95% CI: 0.22-0.61 and OR: 0.56, 95% CI: 0.35-0.89 respectively). LOS ≥ 10 days had 3.24 times the odds of 24- and 48-hour opioid administration compared to LOS ≤ 10 days (OR: 3.24, 95% CI 1.11-9.42; OR: 2.98, 95% CI 1.38-6.41, respectively). The most common complication was post-operative delirium, with PNB more likely to present with any complication compared to GA (OR= 1.88, 95% CI 1.09-3.26). There was no difference when comparing LIA to general anesthesia. Our findings suggest PNB for hip fracture can help limit the use of post-operative opioids with adequate pain relief. Regional analgesia does not seem to avoid complications such as delirium. • Hip fracture patients treated with peripheral nerve block used less opioids than those who had general anesthesia. • Complication rates were higher in patients treated with peripheral nerve block as compared to general anesthesia. • Pain control was better among patients treated with peripheral nerve block. [ABSTRACT FROM AUTHOR]

Published
2023
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35. Pain, Analgesic Use, and Patient Satisfaction With Spinal Versus General Anesthesia for Hip Fracture Surgery : A Randomized Clinical Trial.

Author

Neuman MD, Feng R, Ellenberg SS, Sieber F, Sessler DI, Magaziner J, Elkassabany N, Schwenk ES, Dillane D, Marcantonio ER, Menio D, Ayad S, Hassan M, Stone T, Papp S, Donegan D, Marshall M, Jaffe JD, Luke C, Sharma B, Azim S, Hymes R, Chin KJ, Sheppard R, Perlman B, Sappenfield J, Hauck E, Hoeft MA, Tierney A, Gaskins LJ, Horan AD, Brown T, Dattilo J, Carson JL, Looke T, Bent S, Franco-Mora A, Hedrick P, Newbern M, Tadros R, Pealer K, Vlassakov K, Buckley C, Gavin L, Gorbatov S, Gosnell J, Steen T, Vafai A, Zeballos J, Hruslinski J, Cardenas L, Berry A, Getchell J, Quercetti N, Bajracharya G, Billow D, Bloomfield M, Cuko E, Elyaderani MK, Hampton R, Honar H, Khoshknabi D, Kim D, Krahe D, Lew MM, Maheshwer CB, Niazi A, Saha P, Salih A, de Swart RJ, Volio A, Bolkus K, DeAngelis M, Dodson G, Gerritsen J, McEniry B, Mitrev L, Kwofie MK, Belliveau A, Bonazza F, Lloyd V, Panek I, Dabiri J, Chavez C, Craig J, Davidson T, Dietrichs C, Fleetwood C, Foley M, Getto C, Hailes S, Hermes S, Hooper A, Koener G, Kohls K, Law L, Lipp A, Losey A, Nelson W, Nieto M, Rogers P, Rutman S, Scales G, Sebastian B, Stanciu T, Lobel G, Giampiccolo M, Herman D, Kaufman M, Murphy B, Pau C, Puzio T, Veselsky M, Apostle K, Boyer D, Fan BC, Lee S, Lemke M, Merchant R, Moola F, Payne K, Perey B, Viskontas D, Poler M, D'Antonio P, O'Neill G, Abdullah A, Fish-Fuhrmann J, Giska M, Fidkowski C, Guthrie ST, Hakeos W, Hayes L, Hoegler J, Nowak K, Beck J, Cuff J, Gaski G, Haaser S, Holzman M, Malekzadeh AS, Ramsey L, Schulman J, Schwartzbach C, Azefor T, Davani A, Jaberi M, Masear C, Haider SB, Chungu C, Ebrahimi A, Fikry K, Marcantonio A, Shelvan A, Sanders D, Clarke C, Lawendy A, Schwartz G, Garg M, Kim J, Caruci J, Commeh E, Cuevas R, Cuff G, Franco L, Furgiuele D, Giuca M, Allman M, Barzideh O, Cossaro J, D'Arduini A, Farhi A, Gould J, Kafel J, Patel A, Peller A, Reshef H, Safur M, Toscano F, Tedore T, Akerman M, Brumberger E, Clark S, Friedlander R, Jegarl A, Lane J, Lyden JP, Mehta N, Murrell MT, Painter N, Ricci W, Sbrollini K, Sharma R, Steel PAD, Steinkamp M, Weinberg R, Wellman DS, Nader A, Fitzgerald P, Ritz M, Bryson G, Craig A, Farhat C, Gammon B, Gofton W, Harris N, Lalonde K, Liew A, Meulenkamp B, Sonnenburg K, Wai E, Wilkin G, Troxell K, Alderfer ME, Brannen J, Cupitt C, Gerhart S, McLin R, Sheidy J, Yurick K, Chen F, Dragert K, Kiss G, Malveaux H, McCloskey D, Mellender S, Mungekar SS, Noveck H, Sagebien C, Biby L, McKelvy G, Richards A, Abola R, Ayala B, Halper D, Mavarez A, Rizwan S, Choi S, Awad I, Flynn B, Henry P, Jenkinson R, Kaustov L, Lappin E, McHardy P, Singh A, Donnelly J, Gonzalez M, Haydel C, Livelsberger J, Pazionis T, Slattery B, Vazquez-Trejo M, Baratta J, Cirullo M, Deiling B, Deschamps L, Glick M, Katz D, Krieg J, Lessin J, Mojica J, Torjman M, Jin R, Salpeter MJ, Powell M, Simmons J, Lawson P, Kukreja P, Graves S, Sturdivant A, Bryant A, Crump SJ, Verrier M, Green J, Menon M, Applegate R, Arias A, Pineiro N, Uppington J, Wolinsky P, Gunnett A, Hagen J, Harris S, Hollen K, Holloway B, Horodyski MB, Pogue T, Ramani R, Smith C, Woods A, Warrick M, Flynn K, Mongan P, Ranganath Y, Fernholz S, Ingersoll-Weng E, Marian A, Seering M, Sibenaller Z, Stout L, Wagner A, Walter A, Wong C, Orwig D, Goud M, Helker C, Mezenghie L, Montgomery B, Preston P, Schwartz JS, Weber R, Fleisher LA, Mehta S, Stephens-Shields AJ, Dinh C, Chelly JE, Goel S, Goncz W, Kawabe T, Khetarpal S, Monroe A, Shick V, Breidenstein M, Dominick T, Friend A, Mathews D, Lennertz R, Sanders R, Akere H, Balweg T, Bo A, Doro C, Goodspeed D, Lang G, Parker M, Rettammel A, Roth M, White M, Whiting P, Allen BFS, Baker T, Craven D, McEvoy M, Turnbo T, Kates S, Morgan M, Willoughby T, Weigel W, Auyong D, Fox E, Welsh T, Cusson B, Dobson S, Edwards C, Harris L, Henshaw D, Johnson K, McKinney G, Miller S, Reynolds J, Segal BS, Turner J, VanEenenaam D, Weller R, Lei J, Treggiari M, Akhtar S, Blessing M, Johnson C, Kampp M, Kunze K, O'Connor M, Looke T, Tadros R, Vlassakov K, Cardenas L, Bolkus K, Mitrev L, Kwofie MK, Dabiri J, Lobel G, Poler M, Giska M, Sanders D, Schwartz G, Giuca M, Tedore T, Nader A, Bryson G, Troxell K, Kiss G, Choi S, Powell M, Applegate R, Warrick M, Ranganath Y, Chelly JE, Lennertz R, Sanders R, Allen BFS, Kates S, Weigel W, Li J, Wijeysundera DN, Kheterpal S, Moore RH, Smith AK, Tosi LL, Looke T, Mehta S, Fleisher L, Hruslinski J, Ramsey L, Langlois C, Mezenghie L, Montgomery B, Oduwole S, and Rose T

Subjects
Aged, Analgesics therapeutic use, Anesthesia, General adverse effects, Canada, Female, Humans, Male, Pain, Pain, Postoperative drug therapy, Patient Satisfaction, Anesthesia, Spinal adverse effects, Hip Fractures surgery
Abstract

Background: The REGAIN (Regional versus General Anesthesia for Promoting Independence after Hip Fracture) trial found similar ambulation and survival at 60 days with spinal versus general anesthesia for hip fracture surgery. Trial outcomes evaluating pain, prescription analgesic use, and patient satisfaction have not yet been reported., Objective: To compare pain, analgesic use, and satisfaction after hip fracture surgery with spinal versus general anesthesia., Design: Preplanned secondary analysis of a pragmatic randomized trial. (ClinicalTrials.gov: NCT02507505)., Setting: 46 U.S. and Canadian hospitals., Participants: Patients aged 50 years or older undergoing hip fracture surgery., Intervention: Spinal or general anesthesia., Measurements: Pain on postoperative days 1 through 3; 60-, 180-, and 365-day pain and prescription analgesic use; and satisfaction with care., Results: A total of 1600 patients were enrolled. The average age was 78 years, and 77% were women. A total of 73.5% (1050 of 1428) of patients reported severe pain during the first 24 hours after surgery. Worst pain over the first 24 hours after surgery was greater with spinal anesthesia (rated from 0 [no pain] to 10 [worst pain imaginable]; mean difference, 0.40 [95% CI, 0.12 to 0.68]). Pain did not differ across groups at other time points. Prescription analgesic use at 60 days occurred in 25% (141 of 563) and 18.8% (108 of 574) of patients assigned to spinal and general anesthesia, respectively (relative risk, 1.33 [CI, 1.06 to 1.65]). Satisfaction was similar across groups., Limitation: Missing outcome data and multiple outcomes assessed., Conclusion: Severe pain is common after hip fracture. Spinal anesthesia was associated with more pain in the first 24 hours after surgery and more prescription analgesic use at 60 days compared with general anesthesia., Primary Funding Source: Patient-Centered Outcomes Research Institute .

Published
2022
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36. Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures: A Randomized Clinical Trial.

Author

O'Toole RV, Joshi M, Carlini AR, Murray CK, Allen LE, Huang Y, Scharfstein DO, O'Hara NN, Gary JL, Bosse MJ, Castillo RC, Bishop JA, Weaver MJ, Firoozabadi R, Hsu JR, Karunakar MA, Seymour RB, Sims SH, Churchill C, Brennan ML, Gonzales G, Reilly RM, Zura RD, Howes CR, Mir HR, Wagstrom EA, Westberg J, Gaski GE, Kempton LB, Natoli RM, Sorkin AT, Virkus WW, Hill LC, Hymes RA, Holzman M, Malekzadeh AS, Schulman JE, Ramsey L, Cuff JAN, Haaser S, Osgood GM, Shafiq B, Laljani V, Lee OC, Krause PC, Rowe CJ, Hilliard CL, Morandi MM, Mullins A, Achor TS, Choo AM, Munz JW, Boutte SJ, Vallier HA, Breslin MA, Frisch HM, Kaufman AM, Large TM, LeCroy CM, Riggsbee C, Smith CS, Crickard CV, Phieffer LS, Sheridan E, Jones CB, Sietsema DL, Reid JS, Ringenbach K, Hayda R, Evans AR, Crisco MJ, Rivera JC, Osborn PM, Kimmel J, Stawicki SP, Nwachuku CO, Wojda TR, Rehman S, Donnelly JM, Caroom C, Jenkins MD, Boulton CL, Costales TG, LeBrun CT, Manson TT, Mascarenhas DC, Nascone JW, Pollak AN, Sciadini MF, Slobogean GP, Berger PZ, Connelly DW, Degani Y, Howe AL, Marinos DP, Montalvo RN, Reahl GB, Schoonover CD, Schroder LK, Vang S, Bergin PF, Graves ML, Russell GV, Spitler CA, Hydrick JM, Teague D, Ertl W, Hickerson LE, Moloney GB, Weinlein JC, Zelle BA, Agarwal A, Karia RA, Sathy AK, Au B, Maroto M, Sanders D, Higgins TF, Haller JM, Rothberg DL, Weiss DB, Yarboro SR, McVey ED, Lester-Ballard V, Goodspeed D, Lang GJ, Whiting PS, Siy AB, Obremskey WT, Jahangir AA, Attum B, Burgos EJ, Molina CS, Rodriguez-Buitrago A, Gajari V, Trochez KM, Halvorson JJ, Miller AN, Goodman JB, Holden MB, McAndrew CM, Gardner MJ, Ricci WM, Spraggs-Hughes A, Collins SC, Taylor TJ, and Zadnik M

Subjects
Adult, Anti-Bacterial Agents administration & dosage, Double-Blind Method, Female, Fracture Fixation, Internal adverse effects, Fractures, Ununited etiology, Humans, Intra-Articular Fractures surgery, Male, Middle Aged, Powders, Probability, Prospective Studies, Surgical Wound Dehiscence etiology, Surgical Wound Infection etiology, Time Factors, Vancomycin administration & dosage, Anti-Bacterial Agents therapeutic use, Gram-Negative Bacterial Infections prevention & control, Gram-Positive Bacterial Infections prevention & control, Surgical Wound Infection prevention & control, Tibial Fractures surgery, Vancomycin therapeutic use
Abstract

Importance: Despite the widespread use of systemic antibiotics to prevent infections in surgically treated patients with fracture, high rates of surgical site infection persist., Objective: To examine the effect of intrawound vancomycin powder in reducing deep surgical site infections., Design, Setting, and Participants: This open-label randomized clinical trial enrolled adult patients with an operatively treated tibial plateau or pilon fracture who met the criteria for a high risk of infection from January 1, 2015, through June 30, 2017, with 12 months of follow-up (final follow-up assessments completed in April 2018) at 36 US trauma centers., Interventions: A standard infection prevention protocol with (n = 481) or without (n = 499) 1000 mg of intrawound vancomycin powder., Main Outcomes and Measures: The primary outcome was a deep surgical site infection within 182 days of definitive fracture fixation. A post hoc comparison assessed the treatment effect on gram-positive and gram-negative-only infections. Other secondary outcomes included superficial surgical site infection, nonunion, and wound dehiscence., Results: The analysis included 980 patients (mean [SD] age, 45.7 [13.7] years; 617 [63.0%] male) with 91% of the expected person-time of follow-up for the primary outcome. Within 182 days, deep surgical site infection was observed in 29 of 481 patients in the treatment group and 46 of 499 patients in the control group. The time-to-event estimated probability of deep infection by 182 days was 6.4% in the treatment group and 9.8% in the control group (risk difference, -3.4%; 95% CI, -6.9% to 0.1%; P = .06). A post hoc analysis of the effect of treatment on gram-positive (risk difference, -3.7%; 95% CI, -6.7% to -0.8%; P = .02) and gram-negative-only (risk difference, 0.3%; 95% CI, -1.6% to 2.1%; P = .78) infections found that the effect of vancomycin powder was a result of its reduction in gram-positive infections., Conclusions and Relevance: Among patients with operatively treated tibial articular fractures at a high risk of infection, intrawound vancomycin powder at the time of definitive fracture fixation reduced the risk of a gram-positive deep surgical site infection, consistent with the activity of vancomycin., Trial Registration: ClinicalTrials.gov Identifier: NCT02227446.

Published
2021
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