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5. DEGRO 2004: 10. Jahreskongress der Deutschen Gesellschaft für Radioonkologie

Author

Wendt, Thomas G., Gademann, G., Pambor, C., Grießbach, I., von Specht, H., Martin, T., Baltas, D., Kurek, R., Röddiger, S., Tunn, U. W., Zamboglou, N., Eich, H. T., Staar, S., Gossmann, A., Hansemann, K., Semrau, R., Skripnitchenko, R., Diehl, V., Müller, R.-P., Sehlen, S., Willich, N., Rühl, U., Lukas, P., Dühmke, E., Engel, K., Tabbert, E., Bolck, M., Knaack, S., Annweiler, H., Krempien, R., Hoppe, H., Harms, W., Daeuber, S., Schorr, O., Treiber, M., Debus, J., Alber, M., Paulsen, F., Birkner, M., Bakai, A., Belka, C., Budach, W., Grosser, K.-H., Kramer, R., Kober, B., Reinert, M., Schneider, P., Hertel, A., Feldmann, H., Csere, P., Hoinkis, C., Rothe, G., Zahn, P., Alheit, H., Cavanaugh, S. X., Kupelian, P., Reddy, C., Pollock, B., Fuss, M., Roeddiger, S., Dannenberg, T., Rogge, B., Drechsler, D., Herrmann, T., Alberti, W., Schwarz, R., Graefen, M., Krüll, A., Rudat, V., Huland, H., Fehr, C., Baum, C., Glocker, S., Nüsslin, F., Heil, T., Lemnitzer, H., Knips, M., Baumgart, O., Thiem, W., Kloetzer, K.-H., Hoffmann, L., Neu, B., Hültenschmidt, B., Sautter-Bihl, M.-L., Micke, O., Seegenschmiedt, M. H., Köppen, D., Klautke, G., Fietkau, R., Schultze, J., Schlichting, G., Koltze, H., Kimmig, B., Glatzel, M., Fröhlich, D., Bäsecke, S., Krauß, A., Strauß, D., Buth, K.-J., Böhme, R., Oehler, W., Bottke, D., Keilholz, U., Heufelder, K., Wiegel, T., Hinkelbein, W., Rödel, C., Papadopoulos, T., Munnes, M., Wirtz, R., Sauer, R., Rödel, F., Lubgan, D., Distel, L., Grabenbauer, G. G., Sak, A., Stüben, G., Pöttgen, C., Grehl, S., Stuschke, M., Müller, K., Pfaffendorf, C., Mayerhofer, A., Köhn, F. M., Ring, J., van Beuningen, D., Meineke, V., Neubauer, S., Keller, U., Wittlinger, M., Riesenbeck, D., Greve, B., Exeler, R., Ibrahim, M., Liebscher, C., Severin, E., Ott, O., Pötter, R., Hammer, J., Hildebrandt, G., Beckmann, M. W., Strnad, V., Fehlauer, F., Tribius, S., Bajrovic, A., Höller, U., Rades, D., Warszawski, A., Baumann, R., Madry-Gevecke, B., Karstens, J. H., Grehn, C., Hensley, F., Berns, C., Wannenmacher, M., Semrau, S., Reimer, T., Gerber, B., Ketterer, P., Koepcke, E., Hänsgen, G., Strauß, H. G., Dunst, J., Füller, J., Kalb, S., Wendt, T., Weitmann, H. D., Waldhäusl, C., Knocke, T.-H., Lamprecht, U., Classen, J., Kaulich, T. W., Aydeniz, B., Bamberg, M., Wiezorek, T., Banz, N., Salz, H., Scheithauer, M., Schwedas, M., Lutterbach, J., Bartelt, S., Frommhold, H., Lambert, J., Hornung, D., Swiderski, S., Walke, M., Siefert, A., Pöllinger, B., Krimmel, K., Schaffer, M., Koelbl, O., Bratengeier, K., Vordermark, D., Flentje, M., Hero, B., Berthold, F., Combs, S. E., Gutwein, S., Schulz-Ertner, D., van Kampen, M., Thilmann, C., Kocher, M., Kunze, S., Schild, S., Ikezaki, K., Müller, B., Sieber, R., Weiß, C., Wolf, I., Wenz, F., Weber, K.-J., Schäfer, J., Engling, A., Laufs, S., Veldwijk, M. R., Milanovic, D., Fleckenstein, K., Zeller, W., Fruehauf, S., Herskind, C., Weinmann, M., Jendrossek, V., Rübe, C., Appold, S., Kusche, S., Hölscher, T., Brüchner, K., Geyer, P., Baumann, M., Kumpf, R., Zimmermann, F., Schill, S., Geinitz, H., Nieder, C., Jeremic, B., Molls, M., Liesenfeld, S., Petrat, H., Hesselmann, S., Schäfer, U., Bruns, F., Horst, E., Wilkowski, R., Assmann, G., Nolte, A., Diebold, J., Löhrs, U., Fritz, P., Hans-Jürgen, K., Mühlnickel, W., Bach, P., Wahlers, B., Kraus, H.-J., Wulf, J., Hädinger, U., Baier, K., Krieger, T., Müller, G., Hof, H., Herfarth, K., Brunner, T., Hahn, S. M., Schreiber, F. S., Rustgi, A. K., McKenna, W. G., Bernhard, E. J., Guckenberger, M., Meyer, K., Willner, J., Schmidt, M., Kolb, M., Li, M., Gong, P., Abdollahi, A., Trinh, T., Huber, P. E., Christiansen, H., Saile, B., Neubauer-Saile, K., Tippelt, S., Rave-Fränk, M., Hermann, R. M., Dudas, J., Hess, C. F., Schmidberger, H., Ramadori, G., Andratschke, N., Price, R., Ang, K.-K., Schwarz, S., Kulka, U., Busch, M., Schlenger, L., Bohsung, J., Eichwurzel, I., Matnjani, G., Sandrock, D., Richter, M., Wurm, R., Budach, V., Feussner, A., Gellermann, J., Jordan, A., Scholz, R., Gneveckow, U., Maier-Hauff, K., Ullrich, R., Wust, P., Felix, R., Waldöfner, N., Seebass, M., Ochel, H.-J., Dani, A., Varkonyi, A., Osvath, M., Szasz, A., Messer, P. M., Blumstein, N. M., Gottfried, H.-W., Schneider, E., Reske, S. N., Röttinger, E. M., Grosu, A.-L., Franz, M., Stärk, S., Weber, W., Heintz, M., Indenkämpen, F., Beyer, T., Lübcke, W., Levegrün, S., Hayen, J., Czech, N., Mbarek, B., Köster, R., Thurmann, H., Todorovic, M., Schuchert, A., Meinertz, T., Münzel, T., Grundtke, H., Hornig, B., Hehr, T., Dilcher, C., Chan, R. C., Mintz, G. S., Kotani, J.-I., Shah, V. M., Canos, D. A., Weissman, N. J., Waksman, R., Wolfram, R., Bürger, B., Schrappe, M., Timmermann, B., Lomax, A., Goitein, G., Schuck, A., Mattke, A., Int-Veen, C., Brecht, I., Bernhard, S., Treuner, J., Koscielniak, E., Heinze, F., Kuhlen, M., von Schorlemer, I., Ahrens, S., Hunold, A., Könemann, S., Winkelmann, W., Jürgens, H., Gerstein, J., Polivka, B., Sykora, K.-W., Bremer, M., Thamm, R., Höpfner, C., Gumprecht, H., Jäger, R., Leonardi, M. A., Frank, A. M., Trappe, A. E., Lumenta, C. B., Östreicher, E., Pinsker, K., Müller, A., Fauser, C., Arnold, W., Henzel, M., Groß, M. W., Engenhart-Cabillic, R., Schüller, P., Palkovic, S., Schröder, J., Wassmann, H., Block, A., Bauer, R., Keffel, F.-W., Theophil, B., Wisser, L., Rogger, M., Niewald, M., van Lengen, V., Mathias, K., Welzel, G., Bohrer, M., Steinvorth, S., Schleußner, C., Leppert, K., Röhrig, B., Strauß, B., van Oorschot, B., Köhler, N., Anselm, R., Winzer, A., Schneider, T., Koch, U., Schönekaes, K., Mücke, R., Büntzel, J., Kisters, K., Scholz, C., Keller, M., Winkler, C., Prause, N., Busch, R., Roth, S., Haas, I., Willers, R., Schultze-Mosgau, S., Wiltfang, J., Kessler, P., Neukam, F. W., Röper, B., Nüse, N., Auer, F., Melzner, W., Geiger, M., Lotter, M., Kuhnt, T., Müller, A. C., Jirsak, N., Gernhardt, C., Schaller, H.-G., Al-Nawas, B., Klein, M. O., Ludwig, C., Körholz, J., Grötz, K. A., Huppers, K., Kunkel, M., Olschewski, T., Bajor, K., Lang, B., Lang, E., Kraus-Tiefenbacher, U., Hofheinz, R., von Gerstenberg-Helldorf, B., Willeke, F., Hochhaus, A., Roebel, M., Oertel, S., Riedl, S., Buechler, M., Foitzik, T., Ludwig, K., Klar, E., Meyer, A., Meier zu Eissen, J., Schwab, D., Meyer, T., Höcht, S., Siegmann, A., Sieker, F., Pigorsch, S., Milicic, B., Acimovic, L., Milisavljevic, S., Radosavljevic-Asic, G., Presselt, N., Baum, R. P., Treutler, D., Bonnet, R., Schmücking, M., Sammour, D., Fink, T., Ficker, J., Pradier, O., Lederer, K., Weiss, E., Hille, A., Welz, S., Sepe, S., Friedel, G., Spengler, W., Susanne, E., Kölbl, O., Hoffmann, W., Wörmann, B., Günther, A., Becker-Schiebe, M., Güttler, J., Schul, C., Nitsche, M., Körner, M. K., Oppenkowski, R., Guntrum, F., Malaimare, L., Raub, M., Schöfl, C., Averbeck, T., Hacker, I., Blank, H., Böhme, C., Imhoff, D., Eberlein, K., Weidauer, S., Böttcher, H. D., Edler, L., Tatagiba, M., Molina, H., Ostertag, C., Milker-Zabel, S., Zabel, A., Schlegel, W., Hartmann, A., Wildfang, I., Kleinert, G., Hamm, K., Reuschel, W., Wehrmann, R., Kneschaurek, P., Münter, M. W., Nikoghosyan, A., Didinger, B., Nill, S., Rhein, B., Küstner, D., Schalldach, U., Eßer, D., Göbel, H., Wördehoff, H., Pachmann, S., Hollenhorst, H., Dederer, K., Evers, C., Lamprecht, J., Dastbaz, A., Schick, B., Fleckenstein, J., Plinkert, P. K., Rübe, Chr., Merz, T., Sommer, B., Mencl, A., Ghilescu, V., Astner, S., Martin, A., Momm, F., Volegova-Neher, N. J., Schulte-Mönting, J., Guttenberger, R., Buchali, A., Blank, E., Sidow, D., Huhnt, W., Gorbatov, T., Heinecke, A., Beckmann, G., Bentia, A.-M., Schmitz, H., Spahn, U., Heyl, V., Prott, P.-J., Galalae, R., Schneider, R., Voith, C., Scheda, A., Hermann, B., Bauer, L., Melchert, F., Kröger, N., Grüneisen, A., Jänicke, F., Zander, A., Zuna, I., Schlöcker, I., Wagner, K., John, E., Dörk, T., Lochhas, G., Houf, M., Lorenz, D., Link, K.-H., Prott, F.-J., Thoma, M., Schauer, R., Heinemann, V., Romano, M., Reiner, M., Quanz, A., Oppitz, U., Bahrehmand, R., Tine, M., Naszaly, A., Patonay, P., Mayer, Á., Markert, K., Mai, S.-K., Lohr, F., Dobler, B., Pinkawa, M., Fischedick, K., Treusacher, P., Cengiz, D., Mager, R., Borchers, H., Jakse, G., Eble, M. J., Asadpour, B., Krenkel, B., Holy, R., Kaplan, Y., Block, T., Czempiel, H., Haverkamp, U., Prümer, B., Christian, T., Benkel, P., Weber, C., Gruber, S., Reimann, P., Blumberg, J., Krause, K., Fischedick, A.-R., Kaube, K., Steckler, K., Henzel, B., Licht, N., Loch, T., Krystek, A., Lilienthal, A., Alfia, H., Claßen, J., Spillner, P., Knutzen, B., Souchon, R., Schulz, I., Grüschow, K., Küchenmeister, U., Vogel, H., Wolff, D., Ramm, U., Licner, J., Rudolf, F., Moog, J., Rahl, C. G., Mose, S., Vorwerk, H., Weiß, E., Engert, A., Seufert, I., Schwab, F., Dahlke, J., Zabelina, T., Krüger, W., Kabisch, H., Platz, V., Wolf, J., Pfistner, B., Stieltjes, B., Wilhelm, T., Schmuecking, M., Junker, K., Treutier, D., Schneider, C. P., Leonhardi, J., Niesen, A., Hoeffken, K., Schmidt, A., Mueller, K.-M., Schmid, I., Lehmann, K., Blumstein, C. G., Kreienberg, R., Freudenberg, L., Kühl, H., Stahl, M., Elo, B., Erichsen, P., Stattaus, H., Welzel, T., Mende, U., Heiland, S., Salter, B. J., Schmid, R., Stratakis, D., Huber, R. M., Haferanke, J., Zöller, N., Henke, M., Lorenzen, J., Grzyska, B., Kuhlmey, A., Adam, G., Hamelmann, V., Bölling, T., Job, H., Panke, J. E., Feyer, P., Püttmann, S., Siekmeyer, B., Jung, H., Gagel, B., Militz, U., Piroth, M., Schmachtenberg, A., Hoelscher, T., Verfaillie, C., Kaminski, B., Lücke, E., Mörtel, H., Eyrich, W., Fritsch, M., Georgi, J.-C., Plathow, C., Zieher, H., Kiessling, F., Peschke, P., Kauczor, H.-U., Licher, J., Schneider, O., Henschler, R., Seidel, C., Kolkmeyer, A., Nguyen, T. P., Janke, K., Michaelis, M., Bischof, M., Stoffregen, C., Lipson, K., Weber, K., Ehemann, V., Jürgen, D., Achanta, P., Thompson, K., Martinez, J. L., Körschgen, T., Pakala, R., Pinnow, E., Hellinga, D., O’Tio, F., Katzer, A., Kaffer, A., Kuechler, A., Steinkirchner, S., Dettmar, N., Cordes, N., Frick, S., Kappler, M., Taubert, H., Bartel, F., Schmidt, H., Bache, M., Frühauf, S., Wenk, T., Litzenberger, K., Erren, M., van Valen, F., Liu, L., Yang, K., Palm, J., Püsken, M., Behe, M., Behr, T. M., Marini, P., Johne, A., Claussen, U., Liehr, T., Steil, V., Moustakis, C., Griessbach, I., Oettel, A., Schaal, C., Reinhold, M., Strasssmann, G., Braun, I., Vacha, P., Richter, D., Osterham, T., Wolf, P., Guenther, G., Miemietz, M., Lazaridis, E. A., Forthuber, B., Sure, M., Klein, J., Saleske, H., Riedel, T., Hirnle, P., Horstmann, G., Schoepgens, H., Van Eck, A., Bundschuh, O., Van Oosterhut, A., Xydis, K., Theodorou, K., Kappas, C., Zurheide, J., Fridtjof, N., Ganswindt, U., Weidner, N., Buchgeister, M., Weigel, B., Müller, S. B., Glashörster, M., Weining, C., Hentschel, B., Sauer, O. A., Kleen, W., Beck, J., Lehmann, D., Ley, S., Fink, C., Puderbach, M., Hosch, W., Schmähl, A., Jung, K., Stoßberg, A., Rolf, E., Damrau, M., Oetzel, D., Maurer, U., Maurer, G., Lang, K., Zumbe, J., Hahm, D., Fees, H., Robrandt, B., Melcher, U., Niemeyer, M., Mondry, A., Kanellopoulos-Niemeyer, V., Karle, H., Jacob-Heutmann, D., Born, C., Mohr, W., Kutzner, J., Thelen, M., Schiebe, M., Pinkert, U., Piasswilm, L., Pohl, F., Garbe, S., Wolf, K., Nour, Y., Barwig, P., Trog, D., Schäfer, C., Herbst, M., Dietl, B., Cartes, M., Schroeder, F., Sigingan-Tek, G., Feierabend, R., Theden, S., Schlieck, A., Gotthardt, M., Glowalla, U., Kremp, S., Hamid, O., Riefenstahl, N., Michaelis, B., Schaal, G., Liebermeister, E., Niewöhner-Desbordes, U., Kowalski, M., Franz, N., Stahl, W., Baumbach, C., Thale, J., Wagner, W., Justus, B., Huston, A. L., Seaborn, R., Rai, P., Rha, S.-W., Sakas, G., Wesarg, S., Zogal, P., Schwald, B., Seibert, H., Berndt-Skorka, R., Seifert, G., Schoenekaes, K., Bilecen, C., Ito, W., Matschuck, G., and Isik, D.

Published
2004
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6. Treatment planning for spinal radiosurgery: A competitive multiplatform benchmark challenge|Bestrahlungsplanung für Wirbelsäulen-Radiochirurgie: Eine kompetitive Multiplattform-Benchmark-Studie

Author

Moustakis C, Chan MKH, Kim J, Nilsson J, Bergman A, Bichay TJ, Palazon Cano I, Cilla S, Deodato F, Doro R, Dunst J, Eich HT, Fau P, Fong M, Haverkamp U, Heinze S, Hildebrandt G, Imhoff D, de Klerck E, Köhn J, Lambrecht U, Loutfi-Krauss B, Ebrahimi F, Masi L, Mayville AH, Mestrovic A, Milder M, Morganti AG, Rades D, Ramm U, Rödel C, Siebert FA, den Toom W, Wang L, Wurster S, Schweikard A, Soltys SG, Ryu S, Blanck O., and Moustakis C, Chan MKH, Kim J, Nilsson J, Bergman A, Bichay TJ, Palazon Cano I, Cilla S, Deodato F, Doro R, Dunst J, Eich HT, Fau P, Fong M, Haverkamp U, Heinze S, Hildebrandt G, Imhoff D, de Klerck E, Köhn J, Lambrecht U, Loutfi-Krauss B, Ebrahimi F, Masi L, Mayville AH, Mestrovic A, Milder M, Morganti AG, Rades D, Ramm U, Rödel C, Siebert FA, den Toom W, Wang L, Wurster S, Schweikard A, Soltys SG, Ryu S, Blanck O.

Subjects
Organs at Risk, Robotic Surgical Procedure, Radiotherapy Planning, Computer-Assisted, Spinal Neoplasm, Radiotherapy Dosage, Multiplatform, Radiosurgery, Thoracic Vertebrae, Re-Irradiation, Algorithm, Benchmarking, Stereotactic body radiation therapy, Spinal radiosurgery, Benchmark study, Radiotherapy, Intensity-Modulated, Neoplasm Recurrence, Local, Multicenter, Dose Fractionation, Treatment planning challenge, Aged, Human
Abstract

To investigate the quality of treatment plans of spinal radiosurgery derived from different planning and delivery systems. The comparisons include robotic delivery and intensity modulated arc therapy (IMAT) approaches. Multiple centers with equal systems were used to reduce a bias based on individual's planning abilities. The study used a series of three complex spine lesions to maximize the difference in plan quality among the various approaches.

Published
2018

7. Dosis-Harmonisierung für die Leber-SBRT

Author

Moustakis, Christos, Wilke, L, Chan, Mark, Schmitt, Daniela, Andratschke, Nicolaus, Boda-Heggemann, Judith, Tanadini-Lang, Stephanie, Albers, D, Alraun, M, Bäumer, Christian, Beckers, E, Brunner, Thomas, Dierl, M, Droege, S, Duma, M-N, Ebrahimi Tazeh Maha, F, Eich, H.T.T., Fleckenstein, J, Ganswindt, U, Gauer, Tobias, Gikka, E, Hafner, M., Haverkamp, U, Heinz, C, Henkenberens, C, Köhn, J, Krieger, T, Hennig, A, Kornhuber, C, Loufti-Kraus, Britta, Mayr, M, Pfeiler, Tina, Pollul, G, Ramm, U, Roeder, F, Salz, H, Schmidhalter, D, Schöffler, J, Schubert, K., Ulm, C, Walke, M, Weigel, R, Wiehle, R, Wiezorek, T, Wolf, U, Zimmer, J, Baus, Wolfgang, Guckenberger, Matthias, and Blanck, Oliver

Published
2019

8. A Multi-Platform Treatment Planning Benchmark Study for Spinal Radiosurgery

Author

Moustakis, C., primary, Chan, M.K.H., additional, Kim, J., additional, Nilsson, J., additional, Bergman, A., additional, Bichay, T.J., additional, Cilla, S., additional, Deodato, F., additional, Doro, R., additional, Eich, H.T.T., additional, Fau, P., additional, Fong, M., additional, Haverkamp, U., additional, Heinze, S., additional, Köhn, J., additional, de Klerck, E.C., additional, Lambrecht, U., additional, Masi, L., additional, Mayville, A.H., additional, Morganti, A.G., additional, Milder, M., additional, Rades, D., additional, Ramm, U., additional, Ryu, S., additional, Soltys, S.G., additional, Tazeh Maha, F. Ebrahimi, additional, Toom, W. den, additional, Wang, L., additional, and Blanck, O., additional

Published
2019
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9. Treatment planning for spinal radiosurgery

Author

Moustakis, C, Chan, MKH, Kim, J, Nilsson, J, Bergman, A, Bichay, TJ, Cano, IP, Cilla, S, Deodato, F, Doro, R, Dunst, J, Eich, HT, Fau, P, Fong, M, Haverkamp, U, Heinze, S, Hildebrandt, G, Imhoff, D, Klerck, Erik, Kohn, J, Lambrecht, U, Loutfi-Krauss, B, Ebrahimi, F, Masi, L, Mayville, A, Mestrovic, A, Milder, Maaike, Morganti, A, Rades, D, Ramm, U, Rodel, C, Siebert, FA, Toom, Willem, Wang, L (Lei), Wurster, S, Schweikard, A, Soltys, SG, Ryu, S, Blanck, O, and Radiotherapy

Published
2018

10. Reference of Plan Comparison Study for Liver-SBRT - Results DEGRO AG/DGMP AK Stereotaxis

Author

Moustakis, C., Blanck, O., Andratschke, N., Boda-Heggemann, J., Wilke, L., Tanadini-Lang, S., Albers, D., Alraun, M., Baeumer, C., Beckers, E., Blaschek, M., Brunner, T., Chan, M. K. H., Dierl, M., Droege, S., Duma, M-N., Ebrahimi, F., Eich, H. T., Fleckenstein, J., Ganswindt, U., Garbe, S., Gkika, E., Heinz, C., Henkenberens, C., Hennig, A., Henning, S., Koehn, J., Kornhuber, C., Kretschmer, M., Krieger, T., Loufti-Kraus, B., Mayr, M., Mensing, T., Pfeiler, T., Pollul, G., Ramm, U., Rieken, S., Roeder, F., Schmidthalter, D., Schmitt, D., Schoeffler, J., Ulm, C., Walke, M., Weigel, R., Wiehle, R., Wiezorek, T., Wolf, U., Zimmer, J., Baus, W., Guckenberger, M., Moustakis, C., Blanck, O., Andratschke, N., Boda-Heggemann, J., Wilke, L., Tanadini-Lang, S., Albers, D., Alraun, M., Baeumer, C., Beckers, E., Blaschek, M., Brunner, T., Chan, M. K. H., Dierl, M., Droege, S., Duma, M-N., Ebrahimi, F., Eich, H. T., Fleckenstein, J., Ganswindt, U., Garbe, S., Gkika, E., Heinz, C., Henkenberens, C., Hennig, A., Henning, S., Koehn, J., Kornhuber, C., Kretschmer, M., Krieger, T., Loufti-Kraus, B., Mayr, M., Mensing, T., Pfeiler, T., Pollul, G., Ramm, U., Rieken, S., Roeder, F., Schmidthalter, D., Schmitt, D., Schoeffler, J., Ulm, C., Walke, M., Weigel, R., Wiehle, R., Wiezorek, T., Wolf, U., Zimmer, J., Baus, W., and Guckenberger, M.

Published
2018

12. Out-of-field dose studies with an anthropomorphic phantom : Comparison of X-rays and particle therapy treatments

Author

La Tessa, C., Berger, T., Kaderka, R., Schardt, D., Körner, C., Ramm, U., Licher, J., Matsufuji, N., Dahlgren, Christina Vallhagen, Lomax, T., Reitz, G., Durante, M., La Tessa, C., Berger, T., Kaderka, R., Schardt, D., Körner, C., Ramm, U., Licher, J., Matsufuji, N., Dahlgren, Christina Vallhagen, Lomax, T., Reitz, G., and Durante, M.

Abstract

Background and purpose: Characterization of the out-of-field dose profile following irradiation of the target with a 3D treatment plan delivered with modern techniques. Methods: An anthropomorphic RANDO phantom was irradiated with a treatment plan designed for a simulated 5×2×5cm 3 tumor volume located in the center of the head. The experiment was repeated with all most common radiation treatment types (photons, protons and carbon ions) and delivery techniques (Intensity Modulated Radiation Therapy, passive modulation and spot scanning). The measurements were performed with active diamond detector and passive thermoluminescence (TLD) detectors to investigate the out-of-field dose both inside and outside the phantom. Results: The highest out-of-field dose values both on the surface and inside the phantom were measured during the treatment with 25 MV photons. In the proximity of the Planned Target Volume (PTV), the lowest lateral dose profile was observed for passively modulated protons mainly because of the presence of the collimator in combination with the chosen volume shape. In the far out-of-field region (above 100 mm from the PTV), passively modulated ions were characterized by a less pronounced dose fall-off in comparison with scanned beams. Overall, the treatment with scanned carbon ions delivered the lowest dose outside the target volume. Conclusions: For the selected PTV, the use of the collimator in proton therapy drastically reduced the dose deposited by ions or photons nearby the tumor. Scanning modulation represents the optimal technique for achieving the highest dose reduction far-out-of-field.

Published
2012
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14. [Radiation load on the skin using a silicone-coated polyamide wound dressing during photon and electron radiotherapy]

Author

Thilmann C, Irenaeus Adamietz, Ramm U, Mose S, Saran F, and Hd, Böttcher

Subjects
Nylons, Photons, Radiotherapy, Silicones, Humans, Electrons, Radiation Dosage, Bandages, Skin
Abstract

Silicone-coated polyamide wound dressing is frequently used for the supportive treatment in patients with radiation induced skin lesions. The use of this kind of dressing during radiotherapy with high energy beams shifts the dose built-up effect towards the skin surface. Thus the dose delivered to the skin increases. The present work quantifies changes of the skin dose by a commercial silicon-coated polyamide wound dressing. The dependence on the beam quality and on different treatment techniques is investigated.Measurements were performed with photon (60Co, 6 MV, 42 MV) and electron (7 MeV, 20 MeV, 40 MeV) beams using thin LiF thermoluminescence dosimeters (TLD) in a perspex phantom. The beams were directed perpendicularly to the phantom surface. For 60Co and 6 MV photon beams the skin dose was evaluated in vivo at different beam arrangements and at a given reference dose.For 60Co, 6 MV and 42 MV photon beams wound dressing caused a dose increase on the surface of the perspex phantom by a factor of 1.65, 1.39 and 1.33 respectively. Using oblique or rotational techniques for 60Co and 6 MV photon irradiation the wound dressing increased the skin dose but less compared to perpendicular beam direction. For electron beams the skin dose is relatively high (from 84% to 92%) and an increase by a dressing has no clinical relevance (factor 1.03 to 1.05).The silicone-coated polyamide wound dressing causes no relevant skin dose increase during radiation treatment with electron beams and can be left on the skin during irradiation. During radiation treatment with photon beams like 60Co and 6 MV the protective procedure should be adapted to skin changes, in case of strong skin reactions a removal during the time of irradiation should be considered.

Published
1996

18. DEGRO 2004

Author

Wendt, Thomas G., primary, Gademann, G., additional, Pambor, C., additional, Grießbach, I., additional, von Specht, H., additional, Martin, T., additional, Baltas, D., additional, Kurek, R., additional, Röddiger, S., additional, Tunn, U. W., additional, Zamboglou, N., additional, Eich, H. T., additional, Staar, S., additional, Gossmann, A., additional, Hansemann, K., additional, Semrau, R., additional, Skripnitchenko, R., additional, Diehl, V., additional, Müller, R.-P., additional, Sehlen, S., additional, Willich, N., additional, Rühl, U., additional, Lukas, P., additional, Dühmke, E., additional, Engel, K., additional, Tabbert, E., additional, Bolck, M., additional, Knaack, S., additional, Annweiler, H., additional, Krempien, R., additional, Hoppe, H., additional, Harms, W., additional, Daeuber, S., additional, Schorr, O., additional, Treiber, M., additional, Debus, J., additional, Alber, M., additional, Paulsen, F., additional, Birkner, M., additional, Bakai, A., additional, Belka, C., additional, Budach, W., additional, Grosser, K.-H., additional, Kramer, R., additional, Kober, B., additional, Reinert, M., additional, Schneider, P., additional, Hertel, A., additional, Feldmann, H., additional, Csere, P., additional, Hoinkis, C., additional, Rothe, G., additional, Zahn, P., additional, Alheit, H., additional, Cavanaugh, S. X., additional, Kupelian, P., additional, Reddy, C., additional, Pollock, B., additional, Fuss, M., additional, Roeddiger, S., additional, Dannenberg, T., additional, Rogge, B., additional, Drechsler, D., additional, Herrmann, T., additional, Alberti, W., additional, Schwarz, R., additional, Graefen, M., additional, Krüll, A., additional, Rudat, V., additional, Huland, H., additional, Fehr, C., additional, Baum, C., additional, Glocker, S., additional, Nüsslin, F., additional, Heil, T., additional, Lemnitzer, H., additional, Knips, M., additional, Baumgart, O., additional, Thiem, W., additional, Kloetzer, K.-H., additional, Hoffmann, L., additional, Neu, B., additional, Hültenschmidt, B., additional, Sautter-Bihl, M.-L., additional, Micke, O., additional, Seegenschmiedt, M. H., additional, Köppen, D., additional, Klautke, G., additional, Fietkau, R., additional, Schultze, J., additional, Schlichting, G., additional, Koltze, H., additional, Kimmig, B., additional, Glatzel, M., additional, Fröhlich, D., additional, Bäsecke, S., additional, Krauß, A., additional, Strauß, D., additional, Buth, K.-J., additional, Böhme, R., additional, Oehler, W., additional, Bottke, D., additional, Keilholz, U., additional, Heufelder, K., additional, Wiegel, T., additional, Hinkelbein, W., additional, Rödel, C., additional, Papadopoulos, T., additional, Munnes, M., additional, Wirtz, R., additional, Sauer, R., additional, Rödel, F., additional, Lubgan, D., additional, Distel, L., additional, Grabenbauer, G. G., additional, Sak, A., additional, Stüben, G., additional, Pöttgen, C., additional, Grehl, S., additional, Stuschke, M., additional, Müller, K., additional, Pfaffendorf, C., additional, Mayerhofer, A., additional, Köhn, F. M., additional, Ring, J., additional, van Beuningen, D., additional, Meineke, V., additional, Neubauer, S., additional, Keller, U., additional, Wittlinger, M., additional, Riesenbeck, D., additional, Greve, B., additional, Exeler, R., additional, Ibrahim, M., additional, Liebscher, C., additional, Severin, E., additional, Ott, O., additional, Pötter, R., additional, Hammer, J., additional, Hildebrandt, G., additional, Beckmann, M. W., additional, Strnad, V., additional, Fehlauer, F., additional, Tribius, S., additional, Bajrovic, A., additional, Höller, U., additional, Rades, D., additional, Warszawski, A., additional, Baumann, R., additional, Madry-Gevecke, B., additional, Karstens, J. H., additional, Grehn, C., additional, Hensley, F., additional, Berns, C., additional, Wannenmacher, M., additional, Semrau, S., additional, Reimer, T., additional, Gerber, B., additional, Ketterer, P., additional, Koepcke, E., additional, Hänsgen, G., additional, Strauß, H. G., additional, Dunst, J., additional, Füller, J., additional, Kalb, S., additional, Wendt, T., additional, Weitmann, H. D., additional, Waldhäusl, C., additional, Knocke, T.-H., additional, Lamprecht, U., additional, Classen, J., additional, Kaulich, T. W., additional, Aydeniz, B., additional, Bamberg, M., additional, Wiezorek, T., additional, Banz, N., additional, Salz, H., additional, Scheithauer, M., additional, Schwedas, M., additional, Lutterbach, J., additional, Bartelt, S., additional, Frommhold, H., additional, Lambert, J., additional, Hornung, D., additional, Swiderski, S., additional, Walke, M., additional, Siefert, A., additional, Pöllinger, B., additional, Krimmel, K., additional, Schaffer, M., additional, Koelbl, O., additional, Bratengeier, K., additional, Vordermark, D., additional, Flentje, M., additional, Hero, B., additional, Berthold, F., additional, Combs, S. E., additional, Gutwein, S., additional, Schulz-Ertner, D., additional, van Kampen, M., additional, Thilmann, C., additional, Kocher, M., additional, Kunze, S., additional, Schild, S., additional, Ikezaki, K., additional, Müller, B., additional, Sieber, R., additional, Weiß, C., additional, Wolf, I., additional, Wenz, F., additional, Weber, K.-J., additional, Schäfer, J., additional, Engling, A., additional, Laufs, S., additional, Veldwijk, M. R., additional, Milanovic, D., additional, Fleckenstein, K., additional, Zeller, W., additional, Fruehauf, S., additional, Herskind, C., additional, Weinmann, M., additional, Jendrossek, V., additional, Rübe, C., additional, Appold, S., additional, Kusche, S., additional, Hölscher, T., additional, Brüchner, K., additional, Geyer, P., additional, Baumann, M., additional, Kumpf, R., additional, Zimmermann, F., additional, Schill, S., additional, Geinitz, H., additional, Nieder, C., additional, Jeremic, B., additional, Molls, M., additional, Liesenfeld, S., additional, Petrat, H., additional, Hesselmann, S., additional, Schäfer, U., additional, Bruns, F., additional, Horst, E., additional, Wilkowski, R., additional, Assmann, G., additional, Nolte, A., additional, Diebold, J., additional, Löhrs, U., additional, Fritz, P., additional, Hans-Jürgen, K., additional, Mühlnickel, W., additional, Bach, P., additional, Wahlers, B., additional, Kraus, H.-J., additional, Wulf, J., additional, Hädinger, U., additional, Baier, K., additional, Krieger, T., additional, Müller, G., additional, Hof, H., additional, Herfarth, K., additional, Brunner, T., additional, Hahn, S. M., additional, Schreiber, F. S., additional, Rustgi, A. K., additional, McKenna, W. G., additional, Bernhard, E. J., additional, Guckenberger, M., additional, Meyer, K., additional, Willner, J., additional, Schmidt, M., additional, Kolb, M., additional, Li, M., additional, Gong, P., additional, Abdollahi, A., additional, Trinh, T., additional, Huber, P. E., additional, Christiansen, H., additional, Saile, B., additional, Neubauer-Saile, K., additional, Tippelt, S., additional, Rave-Fränk, M., additional, Hermann, R. M., additional, Dudas, J., additional, Hess, C. F., additional, Schmidberger, H., additional, Ramadori, G., additional, Andratschke, N., additional, Price, R., additional, Ang, K.-K., additional, Schwarz, S., additional, Kulka, U., additional, Busch, M., additional, Schlenger, L., additional, Bohsung, J., additional, Eichwurzel, I., additional, Matnjani, G., additional, Sandrock, D., additional, Richter, M., additional, Wurm, R., additional, Budach, V., additional, Feussner, A., additional, Gellermann, J., additional, Jordan, A., additional, Scholz, R., additional, Gneveckow, U., additional, Maier-Hauff, K., additional, Ullrich, R., additional, Wust, P., additional, Felix, R., additional, Waldöfner, N., additional, Seebass, M., additional, Ochel, H.-J., additional, Dani, A., additional, Varkonyi, A., additional, Osvath, M., additional, Szasz, A., additional, Messer, P. M., additional, Blumstein, N. M., additional, Gottfried, H.-W., additional, Schneider, E., additional, Reske, S. N., additional, Röttinger, E. M., additional, Grosu, A.-L., additional, Franz, M., additional, Stärk, S., additional, Weber, W., additional, Heintz, M., additional, Indenkämpen, F., additional, Beyer, T., additional, Lübcke, W., additional, Levegrün, S., additional, Hayen, J., additional, Czech, N., additional, Mbarek, B., additional, Köster, R., additional, Thurmann, H., additional, Todorovic, M., additional, Schuchert, A., additional, Meinertz, T., additional, Münzel, T., additional, Grundtke, H., additional, Hornig, B., additional, Hehr, T., additional, Dilcher, C., additional, Chan, R. C., additional, Mintz, G. S., additional, Kotani, J.-I., additional, Shah, V. M., additional, Canos, D. A., additional, Weissman, N. J., additional, Waksman, R., additional, Wolfram, R., additional, Bürger, B., additional, Schrappe, M., additional, Timmermann, B., additional, Lomax, A., additional, Goitein, G., additional, Schuck, A., additional, Mattke, A., additional, Int-Veen, C., additional, Brecht, I., additional, Bernhard, S., additional, Treuner, J., additional, Koscielniak, E., additional, Heinze, F., additional, Kuhlen, M., additional, von Schorlemer, I., additional, Ahrens, S., additional, Hunold, A., additional, Könemann, S., additional, Winkelmann, W., additional, Jürgens, H., additional, Gerstein, J., additional, Polivka, B., additional, Sykora, K.-W., additional, Bremer, M., additional, Thamm, R., additional, Höpfner, C., additional, Gumprecht, H., additional, Jäger, R., additional, Leonardi, M. A., additional, Frank, A. M., additional, Trappe, A. E., additional, Lumenta, C. B., additional, Östreicher, E., additional, Pinsker, K., additional, Müller, A., additional, Fauser, C., additional, Arnold, W., additional, Henzel, M., additional, Groß, M. W., additional, Engenhart-Cabillic, R., additional, Schüller, P., additional, Palkovic, S., additional, Schröder, J., additional, Wassmann, H., additional, Block, A., additional, Bauer, R., additional, Keffel, F.-W., additional, Theophil, B., additional, Wisser, L., additional, Rogger, M., additional, Niewald, M., additional, van Lengen, V., additional, Mathias, K., additional, Welzel, G., additional, Bohrer, M., additional, Steinvorth, S., additional, Schleußner, C., additional, Leppert, K., additional, Röhrig, B., additional, Strauß, B., additional, van Oorschot, B., additional, Köhler, N., additional, Anselm, R., additional, Winzer, A., additional, Schneider, T., additional, Koch, U., additional, Schönekaes, K., additional, Mücke, R., additional, Büntzel, J., additional, Kisters, K., additional, Scholz, C., additional, Keller, M., additional, Winkler, C., additional, Prause, N., additional, Busch, R., additional, Roth, S., additional, Haas, I., additional, Willers, R., additional, Schultze-Mosgau, S., additional, Wiltfang, J., additional, Kessler, P., additional, Neukam, F. W., additional, Röper, B., additional, Nüse, N., additional, Auer, F., additional, Melzner, W., additional, Geiger, M., additional, Lotter, M., additional, Kuhnt, T., additional, Müller, A. C., additional, Jirsak, N., additional, Gernhardt, C., additional, Schaller, H.-G., additional, Al-Nawas, B., additional, Klein, M. O., additional, Ludwig, C., additional, Körholz, J., additional, Grötz, K. A., additional, Huppers, K., additional, Kunkel, M., additional, Olschewski, T., additional, Bajor, K., additional, Lang, B., additional, Lang, E., additional, Kraus-Tiefenbacher, U., additional, Hofheinz, R., additional, von Gerstenberg-Helldorf, B., additional, Willeke, F., additional, Hochhaus, A., additional, Roebel, M., additional, Oertel, S., additional, Riedl, S., additional, Buechler, M., additional, Foitzik, T., additional, Ludwig, K., additional, Klar, E., additional, Meyer, A., additional, Meier zu Eissen, J., additional, Schwab, D., additional, Meyer, T., additional, Höcht, S., additional, Siegmann, A., additional, Sieker, F., additional, Pigorsch, S., additional, Milicic, B., additional, Acimovic, L., additional, Milisavljevic, S., additional, Radosavljevic-Asic, G., additional, Presselt, N., additional, Baum, R. P., additional, Treutler, D., additional, Bonnet, R., additional, Schmücking, M., additional, Sammour, D., additional, Fink, T., additional, Ficker, J., additional, Pradier, O., additional, Lederer, K., additional, Weiss, E., additional, Hille, A., additional, Welz, S., additional, Sepe, S., additional, Friedel, G., additional, Spengler, W., additional, Susanne, E., additional, Kölbl, O., additional, Hoffmann, W., additional, Wörmann, B., additional, Günther, A., additional, Becker-Schiebe, M., additional, Güttler, J., additional, Schul, C., additional, Nitsche, M., additional, Körner, M. K., additional, Oppenkowski, R., additional, Guntrum, F., additional, Malaimare, L., additional, Raub, M., additional, Schöfl, C., additional, Averbeck, T., additional, Hacker, I., additional, Blank, H., additional, Böhme, C., additional, Imhoff, D., additional, Eberlein, K., additional, Weidauer, S., additional, Böttcher, H. D., additional, Edler, L., additional, Tatagiba, M., additional, Molina, H., additional, Ostertag, C., additional, Milker-Zabel, S., additional, Zabel, A., additional, Schlegel, W., additional, Hartmann, A., additional, Wildfang, I., additional, Kleinert, G., additional, Hamm, K., additional, Reuschel, W., additional, Wehrmann, R., additional, Kneschaurek, P., additional, Münter, M. W., additional, Nikoghosyan, A., additional, Didinger, B., additional, Nill, S., additional, Rhein, B., additional, Küstner, D., additional, Schalldach, U., additional, Eßer, D., additional, Göbel, H., additional, Wördehoff, H., additional, Pachmann, S., additional, Hollenhorst, H., additional, Dederer, K., additional, Evers, C., additional, Lamprecht, J., additional, Dastbaz, A., additional, Schick, B., additional, Fleckenstein, J., additional, Plinkert, P. K., additional, Rübe, Chr., additional, Merz, T., additional, Sommer, B., additional, Mencl, A., additional, Ghilescu, V., additional, Astner, S., additional, Martin, A., additional, Momm, F., additional, Volegova-Neher, N. J., additional, Schulte-Mönting, J., additional, Guttenberger, R., additional, Buchali, A., additional, Blank, E., additional, Sidow, D., additional, Huhnt, W., additional, Gorbatov, T., additional, Heinecke, A., additional, Beckmann, G., additional, Bentia, A.-M., additional, Schmitz, H., additional, Spahn, U., additional, Heyl, V., additional, Prott, P.-J., additional, Galalae, R., additional, Schneider, R., additional, Voith, C., additional, Scheda, A., additional, Hermann, B., additional, Bauer, L., additional, Melchert, F., additional, Kröger, N., additional, Grüneisen, A., additional, Jänicke, F., additional, Zander, A., additional, Zuna, I., additional, Schlöcker, I., additional, Wagner, K., additional, John, E., additional, Dörk, T., additional, Lochhas, G., additional, Houf, M., additional, Lorenz, D., additional, Link, K.-H., additional, Prott, F.-J., additional, Thoma, M., additional, Schauer, R., additional, Heinemann, V., additional, Romano, M., additional, Reiner, M., additional, Quanz, A., additional, Oppitz, U., additional, Bahrehmand, R., additional, Tine, M., additional, Naszaly, A., additional, Patonay, P., additional, Mayer, Á., additional, Markert, K., additional, Mai, S.-K., additional, Lohr, F., additional, Dobler, B., additional, Pinkawa, M., additional, Fischedick, K., additional, Treusacher, P., additional, Cengiz, D., additional, Mager, R., additional, Borchers, H., additional, Jakse, G., additional, Eble, M. J., additional, Asadpour, B., additional, Krenkel, B., additional, Holy, R., additional, Kaplan, Y., additional, Block, T., additional, Czempiel, H., additional, Haverkamp, U., additional, Prümer, B., additional, Christian, T., additional, Benkel, P., additional, Weber, C., additional, Gruber, S., additional, Reimann, P., additional, Blumberg, J., additional, Krause, K., additional, Fischedick, A.-R., additional, Kaube, K., additional, Steckler, K., additional, Henzel, B., additional, Licht, N., additional, Loch, T., additional, Krystek, A., additional, Lilienthal, A., additional, Alfia, H., additional, Claßen, J., additional, Spillner, P., additional, Knutzen, B., additional, Souchon, R., additional, Schulz, I., additional, Grüschow, K., additional, Küchenmeister, U., additional, Vogel, H., additional, Wolff, D., additional, Ramm, U., additional, Licner, J., additional, Rudolf, F., additional, Moog, J., additional, Rahl, C. G., additional, Mose, S., additional, Vorwerk, H., additional, Weiß, E., additional, Engert, A., additional, Seufert, I., additional, Schwab, F., additional, Dahlke, J., additional, Zabelina, T., additional, Krüger, W., additional, Kabisch, H., additional, Platz, V., additional, Wolf, J., additional, Pfistner, B., additional, Stieltjes, B., additional, Wilhelm, T., additional, Schmuecking, M., additional, Junker, K., additional, Treutier, D., additional, Schneider, C. P., additional, Leonhardi, J., additional, Niesen, A., additional, Hoeffken, K., additional, Schmidt, A., additional, Mueller, K.-M., additional, Schmid, I., additional, Lehmann, K., additional, Blumstein, C. G., additional, Kreienberg, R., additional, Freudenberg, L., additional, Kühl, H., additional, Stahl, M., additional, Elo, B., additional, Erichsen, P., additional, Stattaus, H., additional, Welzel, T., additional, Mende, U., additional, Heiland, S., additional, Salter, B. J., additional, Schmid, R., additional, Stratakis, D., additional, Huber, R. M., additional, Haferanke, J., additional, Zöller, N., additional, Henke, M., additional, Lorenzen, J., additional, Grzyska, B., additional, Kuhlmey, A., additional, Adam, G., additional, Hamelmann, V., additional, Bölling, T., additional, Job, H., additional, Panke, J. E., additional, Feyer, P., additional, Püttmann, S., additional, Siekmeyer, B., additional, Jung, H., additional, Gagel, B., additional, Militz, U., additional, Piroth, M., additional, Schmachtenberg, A., additional, Hoelscher, T., additional, Verfaillie, C., additional, Kaminski, B., additional, Lücke, E., additional, Mörtel, H., additional, Eyrich, W., additional, Fritsch, M., additional, Georgi, J.-C., additional, Plathow, C., additional, Zieher, H., additional, Kiessling, F., additional, Peschke, P., additional, Kauczor, H.-U., additional, Licher, J., additional, Schneider, O., additional, Henschler, R., additional, Seidel, C., additional, Kolkmeyer, A., additional, Nguyen, T. P., additional, Janke, K., additional, Michaelis, M., additional, Bischof, M., additional, Stoffregen, C., additional, Lipson, K., additional, Weber, K., additional, Ehemann, V., additional, Jürgen, D., additional, Achanta, P., additional, Thompson, K., additional, Martinez, J. L., additional, Körschgen, T., additional, Pakala, R., additional, Pinnow, E., additional, Hellinga, D., additional, O’Tio, F., additional, Katzer, A., additional, Kaffer, A., additional, Kuechler, A., additional, Steinkirchner, S., additional, Dettmar, N., additional, Cordes, N., additional, Frick, S., additional, Kappler, M., additional, Taubert, H., additional, Bartel, F., additional, Schmidt, H., additional, Bache, M., additional, Frühauf, S., additional, Wenk, T., additional, Litzenberger, K., additional, Erren, M., additional, van Valen, F., additional, Liu, L., additional, Yang, K., additional, Palm, J., additional, Püsken, M., additional, Behe, M., additional, Behr, T. 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A., additional, Forthuber, B., additional, Sure, M., additional, Klein, J., additional, Saleske, H., additional, Riedel, T., additional, Hirnle, P., additional, Horstmann, G., additional, Schoepgens, H., additional, Van Eck, A., additional, Bundschuh, O., additional, Van Oosterhut, A., additional, Xydis, K., additional, Theodorou, K., additional, Kappas, C., additional, Zurheide, J., additional, Fridtjof, N., additional, Ganswindt, U., additional, Weidner, N., additional, Buchgeister, M., additional, Weigel, B., additional, Müller, S. B., additional, Glashörster, M., additional, Weining, C., additional, Hentschel, B., additional, Sauer, O. A., additional, Kleen, W., additional, Beck, J., additional, Lehmann, D., additional, Ley, S., additional, Fink, C., additional, Puderbach, M., additional, Hosch, W., additional, Schmähl, A., additional, Jung, K., additional, Stoßberg, A., additional, Rolf, E., additional, Damrau, M., additional, Oetzel, D., additional, Maurer, U., additional, Maurer, G., additional, Lang, K., additional, Zumbe, J., additional, Hahm, D., additional, Fees, H., additional, Robrandt, B., additional, Melcher, U., additional, Niemeyer, M., additional, Mondry, A., additional, Kanellopoulos-Niemeyer, V., additional, Karle, H., additional, Jacob-Heutmann, D., additional, Born, C., additional, Mohr, W., additional, Kutzner, J., additional, Thelen, M., additional, Schiebe, M., additional, Pinkert, U., additional, Piasswilm, L., additional, Pohl, F., additional, Garbe, S., additional, Wolf, K., additional, Nour, Y., additional, Barwig, P., additional, Trog, D., additional, Schäfer, C., additional, Herbst, M., additional, Dietl, B., additional, Cartes, M., additional, Schroeder, F., additional, Sigingan-Tek, G., additional, Feierabend, R., additional, Theden, S., additional, Schlieck, A., additional, Gotthardt, M., additional, Glowalla, U., additional, Kremp, S., additional, Hamid, O., additional, Riefenstahl, N., additional, Michaelis, B., additional, Schaal, G., additional, Liebermeister, E., additional, Niewöhner-Desbordes, U., additional, Kowalski, M., additional, Franz, N., additional, Stahl, W., additional, Baumbach, C., additional, Thale, J., additional, Wagner, W., additional, Justus, B., additional, Huston, A. L., additional, Seaborn, R., additional, Rai, P., additional, Rha, S.-W., additional, Sakas, G., additional, Wesarg, S., additional, Zogal, P., additional, Schwald, B., additional, Seibert, H., additional, Berndt-Skorka, R., additional, Seifert, G., additional, Schoenekaes, K., additional, Bilecen, C., additional, Ito, W., additional, Matschuck, G., additional, and Isik, D., additional

Published
2004
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19. Measurements of the Signal-to-Noise Ratio with ˵EPID QC Phantom®″ and ˵epidSoft 2.0″ from PTW.

Author

Liebich, J., Licher, J., Scherf, C., Moog, J., Kara, E., and Ramm, U.

Abstract

Electronic portal imaging device (EPID) are used for patient setup during radiotherapy sessions. The purpose of this study was to evaluate the EPID QC Phantom® developed by PTW for quality assurance (QA) and quality control (QC). We used the Software epidSoft 2.0 provided with the phantom for analyzing the images from the EPID. Measurements were performed using the Elekta iViewGTTM on a linear accelerator with 6 MV x-ray beam. The parameters linearity, signal-to-noise ratio (SNR), modulation-transfer-function (MTF) and the low contrast resolution are detected by different areas in the phantom. Analyzing images exported from the EPID Software and imported to epidSoft as various image formats we found inconsistencies. For examining the cause, calculations with Matlab® were performed. [ABSTRACT FROM AUTHOR]

Published
2009
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36. Quasi-discretization of the electron continuum emitted in collisions of 0.6 MeV u-1Au11+with noble gases

Author

Hagmann, S, primary, Wolff, W, additional, Shinpaugh, J L, additional, Wolf, H E, additional, Olson, R E, additional, Bhalla, C P, additional, Shingal, R, additional, Kelbch, C, additional, Herrmann, R, additional, Jagutzki, O, additional, Dorner, R, additional, Koch, R, additional, Euler, J, additional, Ramm, U, additional, Lencinas, S, additional, Dangendorf, V, additional, Unverzagt, M, additional, Mann, R, additional, Mokler, P, additional, Ullrich, J, additional, Schmidt-Bocking, H, additional, and Cocke, C L, additional

Published
1992
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37. °-Electron emission in fast heavy ion atom collisions

Author

Schmidt-Böcking, H., primary, Ramm, U., additional, Kraft, G., additional, Ullrich, J., additional, Berg, H., additional, Kelbch, C., additional, Olson, R.E., additional, DuBois, R., additional, Hagmann, S., additional, and Jiazhen, F., additional

Published
1992
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38. Usability and accuracy of high-resolution detectors for daily quality assurance for robotic radiosurgery

Author

Loutfi-Krauss Britta, Damme Marie-Christin, Stelljes Tenzin Sonam, Chan Mark KH, Siebert Frank-Andre, Poppe Björn, Ramm Ulla, and Blanck Oliver

Subjects
cyberknife, robotic radiosurgery, automatic quality assurance, high-resolution arrays, gafchromic film, Medicine
Abstract

For daily CyberKnife QA a Winston-Lutz-Test (Automated-Quality-Assurance, AQA) is used to determine sub-millimeter deviations in beam delivery accuracy. This test is performed using gafchromic film, an extensive and user-dependent method requiring the use of disposables. We therefore analyzed the usability and accuracy of high-resolution detector arrays. We analyzed a liquid-filled ionization-chamber array (Octavius 1000SRS, PTW, Germany), which has a central resolution of 2.5mm. To test sufficient sensitivity, beam profiles with robot shifts of 0.1mm along the arrays' axes were measured. The detected deviation between the shifted and central profile were compared to the real robot's position. We then compared the results to the SRS-Profiler (SunNuclear, USA) with 4.0mm resolution and to the Nonius (QUART, Germany), a single-line diode detector with 2.8mm resolution. Finally, AQA variance and usability were analyzed performing a number of AQA tests over time, which required the use of specially designed fixtures for each array, and the results were compared to film. Concerning sensitivity, the 1000SRS detected the beam profile shifts with a maximum difference of 0.11mm (mean deviation = 0.03mm) compared to the actual robot shift. The Nonius and SRS-Profiler showed differences of up to 0.15mm and 0.69mm with mean deviation of 0.05mm and 0.18mm, respectively. Analyzing the variation of AQA results over time, the 1000SRS showed a comparable standard deviation to film (0.26mm vs. 0.18mm). The SRS-Profiler and the Nonius showed a standard deviation of 0.16mm and 0.24mm, respectively. The 1000SRS seems to provide equivalent accuracy and sensitivity to the gold standard film when performing daily AQA tests. Compared to other detectors in our study the sensitivity as well as the accuracy of the 1000SRS appears to be superior and more user-friendly. Furthermore, no significant modification of the standard AQA procedure is required when introducing 1000SRS for CyberKnife AQA.

Published
2017
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39. Verstärkung der radiotherapeutischen Wirkung auf HeLa-Zellen durch Gemcitabine.

Author

Mose, S, Karapetian, M, Jüling-Pohlit, L, Taborski, B, Ramm, U, Damrau, M, Rahn, A, and Böttcher, H D

Abstract

Background: Gemcitabine (2'.2'-difluorodeoxycytidine; dFdC) is a new nucleoside analog with promising activity in different solid tumors in vivo and in vitro. As published up to now, combined with irradiation dFdC demonstrates a radiosensitizing effect on pancreas and colon carcinoma cell lines. We investigated the influence of dFdC on the radiosensitization of human squamous carcinoma cells of the cervix (HeLa-cells, ATCC CCL-2).Material and Methods: Under standardized conditions monolayer cultures of HeLa-cells were incubated in medium with dFdC for different times (4 to 24 hours) and exposed to different concentrations (0.003, 0.01 and 0.03 mumol/l). Irradiation (2 to 6 Gy, electron beam) followed immediately or 12 hours after dFdC-exposure. Cell survival was determined by colony forming assay. Using the linear-quadratic model cell survival curves were fit after correction for drug-induced cytotoxicity and the mean inactivation dose (MID) was calculated. Radiation enhancement was defined as the ratio MIDRT(= Control)/MIDRT + dFdC > 1.Results: Exposed to gemcitabine for 4 and 8 hours and followed by immediate irradiation the radiation enhancement ratio (Table 1) is 1.07 to 1.14 and 1.04 to 1.22, respectively, if dFdC concentration is > or = 0.01 to 0.03 mumol/l. Further increase of the irradiation effect is demonstrated in cells exposed to > or = 0.003 to 0.03 mumol/l dFdC for 16 and 24 hours (radiation enhancement ratio 1.08 to 2.0 and 1.08 to 2.48, respectively) (Figure 3). If irradiation is applied 12 hours after 24-hour-exposure (0.01 and 0.03 mumol/l) the enhancement ratio was 1.18 and 1.7, respectively (Figure 4).Conclusions: In cell cultures the assays combining irradiation with dFdC demonstrate that dFdC is a potent radiation sensitizer of HeLa-cells. The effect of irradiation on cells pre-treated with non- and hardly cytotoxic concentrations of dFdC is increased in dependence of dose and time of exposure. [ABSTRACT FROM AUTHOR]

Published
1999

47. Advantages of 3D printed patient-individual moulds in brachytherapy for facial skin cancer.

Author

Licher J, Achenbach J, Köhn J, Diefenhardt M, Fleischmann M, Rödel C, Tselis N, Ramm U, and Scherf C

Abstract

Purpose: Facial skin cancer of 42 elderly frail patients was treated with individualised 3D-printed mould applicators for high-dose-rate (HDR) brachytherapy. The dosimetric outcome was compared to conventionally manufactured individual moulds used before., Methods: Tumour-adapted HDR brachytherapy source paths were pre-planned and dosimetrically optimised in the brachytherapy treatment planning system (TPS) using computed tomography (CT) data and considered in the design of the patient-individual moulds. Dosimetric outcome for the planning target volumes and organs at risk were statistically evaluated and compared for pre-planning, final clinical treatment planning with TG-43 formalism and retrospective tissue, material and CT density related TG-186 calculations., Results: Pre-planning allows reliable brachytherapy source paths design to achieve intended dosimetric clinical goals. The 3D-printed patient-specific moulds show a clear advantage in the dosimetric coverage of the target volume (improving D 90 from 98.3% to 104.3%) and the protection of the relevant organs at risk (reduction up to 30% of maximum Dose). With the 3D-printed moulds only minor deviations were observed for TG-43 and TG-186 dose recalculations of the treated plans., Conclusion: Customised 3D printed moulds offer a safe and efficient technique to treat facial skin cancer in critical locations and complex clinical situations with HDR brachytherapy. The two-step planning process results in reliable PTV dose coverage and efficient sparing of eye lenses and eyeballs. Dosimetric outcome and interfractional position reproducibility with 3D printed moulds were superior to conventionally manufactured facial moulds with respect to the clinical goals., Competing Interests: Declarations. Conflict of interest: J. Licher, J. Achenbach, J. Köhn, M. Diefenhardt, M. Fleischmann, C. Rödel, N. Tselis, U. Ramm and C. Scherf declare that they have no competing interests. Ethical standards: This retrospective study was initially approved by the local Ethics Committee (ID: 2021-564). The data used in this study were obtained from previous clinical practice, and the patients’ identification and personal information was protected anonymously. The authors followed institutional ethical protocols. Patients whose images are part of this publication gave their express consent for any images taken during treatment to be published for scientific purposes., (© 2025. The Author(s).)

Published
2025
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48. Stereotactic body radiotherapy with volumetric intensity-modulated arc therapy and flattening filter-free beams: dosimetric considerations.

Author

Brekner MC, Imhoff D, Rödel C, Filmann N, Licher J, Ramm U, and Köhn J

Subjects
Humans, Retrospective Studies, Radiotherapy Dosage, Radiotherapy Planning, Computer-Assisted methods, Radiotherapy, Intensity-Modulated methods, Radiosurgery methods, Liver Neoplasms diagnostic imaging, Liver Neoplasms radiotherapy
Abstract

Purpose: The present study comparatively evaluates the impact of energy-matched flattening filter-free (FFF) photon beams with different energy levels on the physical-dosimetric quality of lung and liver stereotactic body radiotherapy (SBRT) treatment plans., Methods: For this purpose, 54 different lung and liver lesions from 44 patients who had already received SBRT combined with volumetric modulated arc therapy (VMAT) were included in this retrospective planning study. Planning computed tomography scans already available were used for the renewed planning with 6 MV, 6 MV-FFF, 10 MV, and 10 MV-FFF under constant planning objectives. The treatment delivery data, dosimetric distributions, and dose-volume histograms as well as parameters such as the conformity index and gradient indices were the basis for the evaluation and comparison of treatment plans., Results: A significant reduction of beam-on time (BOT) was achieved due to the high dose rates of FFF beams. In addition, we showed that for FFF beams compared to flattened beams of the same energy level, smaller planning target volumes (PTV) require fewer monitor units (MU) than larger PTVs. An equal to slightly superior target volume coverage and sparing of healthy tissue as well as organs at risk in both lung and liver lesions were found. Significant differences were seen mainly in the medium to lower dose range., Conclusion: We found that FFF beams together with VMAT represent an excellent combination for SBRT of lung or liver lesions with shortest BOT for 10 MV-FFF but significant dose savings for 6 MV-FFF in lung lesions., (© 2023. The Author(s).)

Published
2024
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49. Robotic stereotactic body radiotherapy for localized prostate cancer: final analysis of the German HYPOSTAT trial.

Author

Krug D, Imhoff D, Haidenberger A, Heßler N, Schäfer J, Huttenlocher S, Chatzikonstantinou G, Fürweger C, Ramm U, König IR, Chun F, Staehler M, Rödel C, Muacevic A, Vonthein R, Dunst J, and Blanck O

Subjects
Male, Humans, Prostate-Specific Antigen, Quality of Life, Prospective Studies, Radiosurgery methods, Robotic Surgical Procedures, Prostatic Neoplasms pathology
Abstract

Purpose: We report results of the first German prospective multicenter single-arm phase II trial (ARO 2013-06; NCT02635256) of hypofractionated robotic stereotactic body radiotherapy (SBRT) for patients with localized prostate cancer (HYPOSTAT)., Methods: Patients eligible for the HYPOSTAT study had localized prostate cancer (cT1‑3 cN0 cM0), Gleason score ≤ 7, prostate-specific antigen (PSA) ≤ 15 ng/ml, prostate volume ≤ 80 cm 3 , and an International Prostate Symptom Score (IPSS) ≤ 12. Initially, inclusion was limited to patients ≥ 75 years or patients 70-74 years with additional risk factors. The trial protocol was later amended to allow for enrolment of patients aged ≥ 60 years. The treatment consisted of 35 Gy delivered in 5 fractions to the prostate and for intermediate- or high-risk patients, also to the proximal seminal vesicles using the CyberKnife system (Accuray Inc., Sunnyvale, CA, USA). Primary endpoint was the rate of treatment-related gastrointestinal or genitourinary grade ≥ 2 toxicity based on the RTOG scale 12-15 months after treatment. Secondary endpoints were acute toxicity, late toxicity, urinary function, quality of life, and PSA response., Results: From July 2016 through December 2018, 85 eligible patients were enrolled and received treatment, of whom 83 could be evaluated regarding the primary endpoint. Patients mostly had intermediate-risk disease with a median PSA value of 7.97 ng/ml and Gleason score of 7a and 7b in 43.5% and 25.9% of patients, respectively. At the final follow-up 12-15 months after treatment, no patient suffered from treatment-related gastrointestinal or genitourinary grade ≥ 2 toxicity. Acute toxicity was mostly mild, with three grade 3 events, and the cumulative rate of grade ≥ 2 genitourinary toxicity was 8.4% (95% CI 4.1-16.4%). There were no major changes in urinary function or quality of life. The median PSA value dropped to 1.18 ng/ml 12-15 months after treatment. There was one patient who developed distant metastases., Conclusion: Robotic SBRT with 35 Gy in 5 fractions was associated with a favorable short-term toxicity profile. Recruitment for the HYPOSTAT‑2 trial (ARO-2018‑4; NCT03795337), which further analyses the late toxicity of this regimen with a planned sample size of 500 patients, is ongoing., (© 2023. The Author(s).)

Published
2023
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50. Customized 3D-printed molds for high dose-rate brachytherapy in facial skin cancer: First clinical experience.

Author

Chatzikonstantinou G, Diefenhardt M, Fleischmann M, Meissner M, Scherf C, Trommel M, Ramm U, Rödel C, Tselis N, and Licher J

Subjects
Humans, Aged, Printing, Three-Dimensional, Radiotherapy Dosage, Melanoma, Cutaneous Malignant, Brachytherapy adverse effects, Skin Neoplasms radiotherapy, Skin Neoplasms etiology, Melanoma radiotherapy, Melanoma etiology
Abstract

Background and Objective: Radiotherapy of elderly, frail patients with facial skin cancer in proximity to critical organs is challenging. This is the first report on clinical experience with facial skin cancer treated by individualized 3D-printer-based mold high-dose-rate (HDR) brachytherapy (BT)., Patients and Methods: Fifteen patients not eligible for radical surgery or definitive external beam radiotherapy (EBRT) were treated with 3D-printer-based mold HDR-BT. Patient selection and treatment were in accordance with multidisciplinary tumor board recommendations. Clinical response, toxicity and cosmesis were analyzed., Results: Median age was 77 years. Histology revealed squamous cell carcinoma in seven, basal cell carcinoma in five, melanoma in situ in one, Lentigo maligna in one, and melanoma in one patient, respectively. Median prescription dose was 39 Gy delivered in once-daily fractions of 3 Gy. After a median follow-up of 12.2 months, local recurrence was observed in one patient with melanoma in situ. Apart from one grade 4 cataract, no other > grade 2 late toxicity was documented., Conclusions: HDR-BT with 3D-printer-based molds for facial skin cancer is a well-tolerated and safe treatment option for elderly, frail patients not eligible for radical surgery or definitive EBRT due to functional inoperability or tumor location., (© 2023 The Authors. Journal der Deutschen Dermatologischen Gesellschaft published by John Wiley & Sons Ltd on behalf of Deutsche Dermatologische Gesellschaft.)

Published
2023
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