27 results on '"Ramis L"'
Search Results
2. P688Degenerative mitral regurgitation valve repair in elderly patients
- Author
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Oliveras Vila, T, Ferrer Sistach, E, Delgado Ramis, L, Lopez Ayerbe, J, Vallejo Camazon, N, Gual Capllonch, F, Garcia Alonso, C, Teis Soley, A, Ruyra Baliarda, X, and Bayes Genis, A
- Published
- 2011
3. Asymmetric sleep in rats: P110
- Author
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RAMIS, L. G., AKAÑRIR, M., APARICIO, S., GARAU, C., TEJADA, S., RIAL, R. V., GAMUNDI, A., and NICOLAU, M. C.
- Published
- 2006
4. Cutaneous involvement in an 8-year-old boy with Ras-associated autoimmune leucoproliferative disorder (RALD)
- Author
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Giacaman, A., primary, Bauzá Alonso, A., additional, Salinas Sanz, J. A., additional, Dapena Díaz, J. L., additional, Ramos Asensio, R., additional, Ferrés Ramis, L., additional, Durán Pastor, M. A., additional, and Martín-Santiago, A., additional
- Published
- 2018
- Full Text
- View/download PDF
5. El proceso de cascada del cuadro de mando integral en empresa del sector forestal
- Author
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Neriz J., Liliana, Ramis L., Francisco, and Bull T., MarÃa Teresa
- Published
- 2005
6. Results of pulmonary veins epicardial ablation with high-intensity focused ultrasounds in atrial fibrillation
- Author
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Ferrer, Br, Delgado Ramis, L, Fernandez Gallego, C, Berastegui, E, Flores, Jb, Colli, Andrea, Camara Rosell, Ml, and Ruyra Baliarda, X.
- Published
- 2012
7. Rapamycin in the Treatment of Blue Rubber Bleb Nevus Syndrome
- Author
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Ferrés-Ramis, L., primary, Knöpfel, N., additional, Salinas-Sanz, J.A., additional, and Martín-Santiago, A., additional
- Published
- 2015
- Full Text
- View/download PDF
8. Rapamicina para el tratamiento del síndrome del nevus azul en tetina de goma
- Author
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Ferrés-Ramis, L., primary, Knöpfel, N., additional, Salinas-Sanz, J.A., additional, and Martín-Santiago, A., additional
- Published
- 2015
- Full Text
- View/download PDF
9. Club 35 Poster Session Wednesday 5 December * Right ventricular systolic function
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Hugues, T., primary, Lacroix-Hugues, V., additional, Yaici, K., additional, Gibelin, P., additional, Cabrita, I., additional, Pires, S., additional, Nunes, A., additional, Sousa, C., additional, Cortez-Dias, N., additional, Pinto, F., additional, Hrynkiewicz-Szymanska, A., additional, Braksator, W., additional, Szymanski, F., additional, Chmielewski, M., additional, Dluzniewski, M., additional, Alonso Fernandez, P., additional, Andres Lahuerta, A., additional, Miro Palau, V., additional, Buendia Fuentes, F., additional, Igual Munoz, B., additional, Osa Saez, A., additional, Quesada Carmona, A., additional, Tejada Ponce, D., additional, Munoz, B., additional, Salvador Sanz, A., additional, Imamura, S., additional, Hirata, K. H., additional, Kubo, T., additional, Orii, M., additional, Tanimono, T., additional, Takemoto, K., additional, Ino, Y., additional, Yamaguchi, T., additional, Imanishi, T., additional, Akasaka, T., additional, Kinoshita, T., additional, Asai, T., additional, Suzuki, T., additional, Krestjyaninov, M., additional, Ruzov, V., additional, Tanimoto, T., additional, Yamano, T., additional, Junca Puig, G., additional, Sistach, E. F., additional, Delgado Ramis, L., additional, Lopez Ayerbe, J., additional, Vallejo Camazon, N., additional, Gual Capllonch, f., additional, Teis Soley, A., additional, Camara Rosell, M., additional, Ruyra Baliarda, X., additional, Bayes-Genis, A., additional, Alonso fernandez, P., additional, Maceira Gonzalez, A., additional, Hernandez, C., additional, Bel Minguez, A., additional, Munoz Igual, B., additional, Montero Argudo, A., additional, Antit, S., additional, fennira, S., additional, Zairi, I., additional, Kamoun, S., additional, Kraiem, S., additional, Matsuyama, A., additional, Van De Heyning, C., additional, Magne, J., additional, Pierard, L., additional, Davin, L., additional, Bruyere, P., additional, De Maeyer, C., additional, Paelinck, B., additional, Vrints, C., additional, Lancellotti, P., additional, Wang, J., additional, fang, f., additional, Liu, M., additional, Liang, Y., additional, Yu, C., additional, Lam, Y., additional, Kenny, C., additional, Monaghan, M., additional, Ercan, S., additional, Kervancioglu, S., additional, Davutoglu, V., additional, Cakici, M., additional, Ozkur, A., additional, Oylumlu, M., additional, Sari, I., additional, Sikora-Puz, A., additional, Mizia, M., additional, Gieszczyk-Strozik, K., additional, Matyjaszczyk-Zbieg, K., additional, Haberka, M., additional, Mizia-Stec, K., additional, Gasior, Z., additional, Wos, S., additional, Deja, M., additional, Jasinski, M., additional, Enescu, O., additional, florescu, M., additional, Mihalcea, D., additional, Rimbas, R., additional, Cinteza, M., additional, and Vinereanu, D., additional
- Published
- 2012
- Full Text
- View/download PDF
10. 739 Results of Pulmonary Veins Epicardial Ablation With High-Intensity Focused Ultrasounds in Atrial Fibrillation
- Author
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Romero-Ferrer, B., primary, Delgado-Ramis, L., additional, Fenández-Gallego, C., additional, Berastegui-García, E., additional, Flores-Sigüenza, J., additional, Colli, A., additional, Cámara-Rosell, M., additional, and Ruyra-Baliarda, X., additional
- Published
- 2012
- Full Text
- View/download PDF
11. 169. Resultados de la ablación epicárdica de las venas pulmonares con ultrasonidos de alta intensidad en la fibrilación auricular
- Author
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Romero Ferrer, B., primary, Delgado Ramis, L., additional, Fernández Gallego, C., additional, Berastegui, E., additional, Flores, J.B., additional, Colli, A., additional, Cámara Rosell, M.L., additional, and Ruyra Baliarda, X., additional
- Published
- 2012
- Full Text
- View/download PDF
12. Poster Session 3: Friday 9 December 2011, 08:30-12:30 * Location: Poster Area
- Author
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Kenny, C., primary, Adhya, S., additional, Dworakowski, R., additional, Brickham, B., additional, Maccarthy, P., additional, Monaghan, M., additional, Guzzo, A., additional, Innocenti, F., additional, Vicidomini, S., additional, Lazzeretti, D., additional, Squarciotta, S., additional, De Villa, E., additional, Donnini, C., additional, Bulletti, F., additional, Guerrini, E., additional, Pini, R., additional, Bendjelid, K., additional, Viale, J., additional, Duperret, S., additional, Piriou, V., additional, Jacques, D., additional, Shahgaldi, K., additional, Silva, C., additional, Pedro, F., additional, Deister, L., additional, Brodin, L.-A., additional, Sahlen, A., additional, Manouras, A., additional, Winter, R., additional, Berjeb, N., additional, Cimadevilla, C., additional, Dreyfus, J., additional, Cueff, C., additional, Malanca, M., additional, Chiampan, A., additional, Vahanian, A., additional, Messika-Zeitoun, D., additional, Muraru, D., additional, Peluso, D., additional, Dal Bianco, L., additional, Beraldo, M., additional, Solda', E., additional, Tuveri, M., additional, Cucchini, U., additional, Al Mamary, A., additional, Badano, L., additional, Iliceto, S., additional, Almuntaser, I., additional, King, G., additional, Norris, S., additional, Daly, C., additional, Ellis, E., additional, Murphy, R., additional, Erdei, T., additional, Denes, M., additional, Kardos, A., additional, Foldesi, C., additional, Temesvari, A., additional, Lengyel, M., additional, Bouzas Mosquera, A., additional, Broullon, F., additional, Alvarez-Garcia, N., additional, Peteiro, J., additional, Barge-Caballero, G., additional, Lopez-Perez, M., additional, Lopez-Sainz, A., additional, Castro-Beiras, A., additional, Luotolahti, M., additional, Luotolahti, H., additional, Kantola, I., additional, Viikari, J., additional, Andersen, M., additional, Ersboell, M., additional, Bro-Jeppesen, J., additional, Gustafsson, F., additional, Koeber, L., additional, Hassager, C., additional, Moller, J., additional, Coisne, D., additional, Diakov, C., additional, Vallet, F., additional, Lequeux, B., additional, Blouin, P., additional, Christiaens, L., additional, Esposito, R., additional, Santoro, A., additional, Schiano Lomoriello, V., additional, Raia, R., additional, Santoro, C., additional, De Simone, G., additional, Galderisi, M., additional, Abdula, G., additional, Kosmala, W., additional, Szczepanik-Osadnik, H., additional, Przewlocka-Kosmala, M., additional, Mysiak, A., additional, O' Moore-Sullivan, T., additional, Marwick, T., additional, Tan, Y. T., additional, Wenzelburger, F., additional, Leyva, F., additional, Sanderson, J., additional, Pichler, P., additional, Syeda, B., additional, Hoefer, P., additional, Zuckermann, A., additional, Binder, T., additional, Fijalkowski, M., additional, Koprowski, A., additional, Galaska, R., additional, Blaut, K., additional, Sworczak, K., additional, Rynkiewicz, A., additional, Lee, S., additional, Kim, W., additional, Jung, L., additional, Yun, H., additional, Song, M., additional, Ko, J., additional, Khalifa, E. A., additional, Szymanski, P., additional, Lipczynska, M., additional, Klisieiwcz, A., additional, Hoffman, P., additional, Jorge, C., additional, Silva Marques, J., additional, Robalo Martins, S., additional, Calisto, C., additional, Mieiro, M., additional, Vieira, S., additional, Correia, M., additional, Carvalho De Sousa, J., additional, Almeida, A., additional, Nunes Diogo, A., additional, Park, C., additional, March, K., additional, Tillin, T., additional, Mayet, J., additional, Chaturvedi, N., additional, Hughes, A., additional, Di Bello, V., additional, Giannini, C., additional, Delle Donne, M., additional, De Sanctis, F., additional, Spontoni, P., additional, Cucco, C., additional, Corciu, A., additional, Grigoratos, C., additional, Bogazzi, F., additional, Balbarini, A., additional, Enescu, O., additional, Suran, B., additional, Florescu, M., additional, Cinteza, M., additional, Vinereanu, D., additional, Higuchi, Y., additional, Iwakura, K., additional, Okamura, A., additional, Date, M., additional, Fujii, K., additional, Cortez-Dias, N., additional, Silva, D., additional, Carrilho-Ferreira, P., additional, Magalhaes, A., additional, Ribeiro, S., additional, Goncalves, S., additional, Fiuza, M., additional, Pinto, F., additional, Placido, R., additional, Bordalo, A., additional, Grzywocz, P., additional, Mizia-Stec, K., additional, Chudek, J., additional, Gasior, Z., additional, Maceira Gonzalez, A. M., additional, Cosin Sales, J., additional, Dalli, E., additional, Igual, B., additional, Diago, J., additional, Aguilar, J., additional, Ruvira, J., additional, Cimino, S., additional, Pedrizzetti, G., additional, Tonti, G., additional, Canali, E., additional, Petronilli, V., additional, Boccalini, F., additional, Mattatelli, A., additional, Hiramoto, Y., additional, Iacoboni, C., additional, Agati, L., additional, Trifunovic, D., additional, Ostojic, M., additional, Vujisic-Tesic, B., additional, Petrovic, M., additional, Nedeljkovic, I., additional, Banovic, M., additional, Boricic-Kostic, M., additional, Draganic, G., additional, Tesic, M., additional, Gavina, C., additional, Lopes, R., additional, Lourenco, A., additional, Almeida, J., additional, Rodrigues, J., additional, Pinho, P., additional, Zamorano, J., additional, Leite-Moreira, A., additional, Rocha-Goncalves, F., additional, Clavel, M.-A., additional, Capoulade, R., additional, Dumesnil, J., additional, Mathieu, P., additional, Despres, J.-P., additional, Pibarot, P., additional, Bull, S., additional, Pitcher, A., additional, Augustine, D., additional, D'arcy, J., additional, Karamitsos, T., additional, Rai, A., additional, Prendergast, B., additional, Becher, H., additional, Neubauer, S., additional, Myerson, S., additional, Magne, J., additional, Donal, E., additional, Davin, L., additional, O'connor, K., additional, Pirlet, C., additional, Rosca, M., additional, Szymanski, C., additional, Cosyns, B., additional, Pierard, L., additional, Lancellotti, P., additional, Calin, A., additional, Popescu, B., additional, Beladan, C., additional, Enache, R., additional, Lupascu, L., additional, Sandu, C., additional, Ginghina, C., additional, Kamperidis, V., additional, Hadjimiltiadis, S., additional, Sianos, G., additional, Anastasiadis, K., additional, Grosomanidis, V., additional, Efthimiadis, G., additional, Karvounis, H., additional, Parharidis, G., additional, Styliadis, I., additional, Gonzalez Canovas, C., additional, Munoz-Esparza, C., additional, Bonaque Gonzalez, J., additional, Fernandez, A., additional, Salar Alcaraz, M., additional, Saura Espin, D., additional, Pinar Bermudez, E., additional, Oliva-Sandoval, M., additional, De La Morena Valenzuela, G., additional, Valdes Chavarri, M., additional, Brochet, E., additional, Lepage, L., additional, Attias, D., additional, Detaint, D., additional, Himbert, D., additional, Iung, B., additional, Pirat, B., additional, Little, S., additional, Chang, S., additional, Tiller, L., additional, Kumar, R., additional, Zoghbi, W., additional, Lee, A. P.-W., additional, Hsiung, M., additional, Wan, S., additional, Wong, R., additional, Luo, F., additional, Fang, F., additional, Xie, J., additional, Underwood, M., additional, Sun, J., additional, Yu, C., additional, Jansen, R., additional, Tietge, W., additional, Sijbrandij, K., additional, Cramer, M., additional, De Heer, L., additional, Kluin, J., additional, Chamuleau, S. A. J., additional, Oliveras Vila, T., additional, Ferrer Sistach, E., additional, Delgado Ramis, L., additional, Lopez Ayerbe, J., additional, Vallejo Camazon, N., additional, Gual Capllonch, F., additional, Garcia Alonso, C., additional, Teis Soley, A., additional, Ruyra Baliarda, X., additional, Bayes Genis, A., additional, Negrea, S., additional, Alexandrescu, C., additional, Bourlon, F., additional, Civaia, F., additional, Dreyfus, G., additional, Paetzold, S., additional, Luha, O., additional, Hoedl, R., additional, Stoschitzky, G., additional, Pfeiffer, K., additional, Zweiker, D., additional, Pieske, B., additional, Maier, R., additional, Sevilla, T., additional, Revilla, A., additional, Lopez, J., additional, Vilacosta, I., additional, Arnold, R., additional, Gomez, I., additional, San Roman, J., additional, Nikcevic, G., additional, Djordjevic Dikic, A., additional, Djordjevic, S., additional, Raspopovic, S., additional, Jovanovic, V., additional, Kircanski, B., additional, Pavlovic, S., additional, Milasinovic, G., additional, Ruiz-Zamora, I., additional, Cabrera Bueno, F., additional, Molina, M., additional, Fernandez-Pastor, J., additional, Pena, J., additional, Linde, A., additional, Barrera, A., additional, Alzueta, J., additional, Bremont, C., additional, Bensaid, A., additional, Alonso, H., additional, Zaghden, O., additional, Nahum, J., additional, Dubois-Rande, J., additional, Gueret, P., additional, Lim, P., additional, Lee, S.-P., additional, Park, K., additional, Kim, H.-R., additional, Lee, J.-H., additional, Ahn, H.-S., additional, Kim, J.-H., additional, Kim, H.-K., additional, Kim, Y.-J., additional, Sohn, D.-W., additional, Niemann, M., additional, Herrmann, S., additional, Hu, K., additional, Liu, D., additional, Beer, M., additional, Ertl, G., additional, Wanner, C., additional, Takenaka, T., additional, Tei, C., additional, Weidemann, F., additional, Madeira, H., additional, Mendes Pedro, M., additional, Brito, D., additional, Ippolito, R., additional, De Palma, D., additional, Gati, S., additional, Oxborough, D., additional, Reed, M., additional, Zaidi, A., additional, Ghani, S., additional, Sheikh, N., additional, Papadakis, M., additional, Sharma, S., additional, Chow, V., additional, Ng, A., additional, Pasqualon, T., additional, Zhao, W., additional, Hanzek, D., additional, Chung, T., additional, Yeoh, T., additional, Kritharides, L., additional, Magda, L., additional, Mihalcea, D., additional, Jinga, D., additional, Mincu, R., additional, Ferrazzi, E., additional, Segato, G., additional, Folino, F., additional, Famoso, G., additional, Senzolo, M., additional, Bellu, R., additional, Corbetti, F., additional, Tona, F., additional, Azevedo, O., additional, Quelhas, I., additional, Guardado, J., additional, Fernandes, M., additional, Pereira, V., additional, Medeiros, R., additional, Sousa, P., additional, Santos, W., additional, Pereira, S., additional, Marques, N., additional, Mimoso, J., additional, Marques, V., additional, Jesus, I., additional, Rustad, L., additional, Nytroen, K., additional, Gullestad, L., additional, Amundsen, B., additional, Aakhus, S., additional, Linhartova, K., additional, Sterbakova, G., additional, Necas, J., additional, Kovalova, S., additional, Cerbak, R., additional, Nelassov, N., additional, Korotkijan, N., additional, Shishkina, A., additional, Gagieva, B., additional, Nagaplev, M., additional, Eroshenko, O., additional, Morgunov, M., additional, Parmon, S., additional, Velthuis, S., additional, Van Gent, M., additional, Post, M., additional, Westermann, C., additional, Mager, J., additional, Snijder, R., additional, Koyalakonda, S. P., additional, Anderson, M., additional, Burgess, M., additional, Bergenzaun, L., additional, Chew, M., additional, Ohlin, H., additional, Gjerdalen, G. F., additional, Hisdal, J., additional, Solberg, E., additional, Andersen, T., additional, Radunovic, Z., additional, Steine, K., additional, Rutz, T., additional, Kuehn, A., additional, Petzuch, K., additional, Pekala, M., additional, Elmenhorst, J., additional, Fratz, S., additional, Mueller, J., additional, Hager, A., additional, Hess, J., additional, Vogt, M., additional, Van Der Linde, D., additional, Van De Laar, I., additional, Wessels, M., additional, Bekkers, J., additional, Moelker, A., additional, Tanghe, H., additional, Van Kooten, F., additional, Oldenburg, R., additional, Bertoli-Avella, A., additional, Roos-Hesselink, J., additional, Cresti, A., additional, Fontani, L., additional, Calabria, P., additional, Capati, E., additional, Severi, S., additional, Lynch, M., additional, Saraf, S., additional, Sandler, B., additional, Yoon, S., additional, Kim, S., additional, Ko, C., additional, Ryu, S., additional, Byun, Y., additional, Seo, H., additional, Ciampi, Q., additional, Rigo, F., additional, Pratali, L., additional, Gherardi, S., additional, Villari, B., additional, Picano, E., additional, Sicari, R., additional, Celutkiene, J., additional, Zakarkaite, D., additional, Skorniakov, V., additional, Zvironaite, V., additional, Grabauskiene, V., additional, Sinicyna, J., additional, Gruodyte, G., additional, Janonyte, K., additional, Laucevicius, A., additional, O'driscoll, J., additional, Schmid, K., additional, Marciniak, A., additional, Saha, A., additional, Gupta, S., additional, Smith, R., additional, Sharma, R., additional, Alvarez Garcia, N., additional, Prada, O., additional, Rodriguez Vilela, A., additional, Barge Caballero, G., additional, Lopez Perez, M., additional, Lopez Sainz, A., additional, Castro Beiras, A., additional, Kochanowski, J., additional, Scislo, P., additional, Piatkowski, R., additional, Grabowski, M., additional, Marchel, M., additional, Roik, M., additional, Kosior, D., additional, Opolski, G., additional, Van De Heyning, C. M., additional, Mahjoub, H., additional, Clausen, H., additional, Basaggianis, C., additional, Newton, J., additional, Del Pasqua, A., additional, Carotti, A., additional, Di Carlo, D., additional, Cetrano, E., additional, Toscano, A., additional, Iacobelli, R., additional, Esposito, C., additional, Chinali, M., additional, Pongiglione, G., additional, Rinelli, G., additional, Larsson, M., additional, Bjallmark, A., additional, Caidahl, K., additional, Brodin, L., additional, Gao, H., additional, Lugiez, M., additional, Guivier, C., additional, Rieu, R., additional, D'hooge, J., additional, Hang, G., additional, Guerin, C., additional, Menard, M., additional, Voigt, J.-U., additional, Dungu, J., additional, Campos, G., additional, Jaffarulla, R., additional, Gomes-Pereira, S., additional, Sutaria, N., additional, Baker, C., additional, Nihoyannopoulos, P., additional, Bellamy, M., additional, Harries, D., additional, Walker, N., additional, Pearson, P., additional, Reiken, J., additional, Batteson, J., additional, Kamdar, R., additional, Murgatroyd, F., additional, D'andrea, A., additional, Riegler, L., additional, Scarafile, R., additional, Pezzullo, E., additional, Salerno, G., additional, Bossone, E., additional, Limongelli, G., additional, Russo, M., additional, Pacileo, G., additional, Calabro', R., additional, Kang, Y., additional, Cui, J., additional, Chen, H., additional, Pan, C., additional, Shu, X., additional, Kiotsekoglou, A., additional, Saha, S., additional, Toole, R., additional, Govind, S., additional, Gopal, A., additional, Crispi, F., additional, Bijnens, B., additional, Sepulveda-Swatson, E., additional, Rojas-Benavente, J., additional, Dominguez, J., additional, Illa, M., additional, Eixarch, E., additional, Sitges, M., additional, Gratacos, E., additional, Prinz, C., additional, Faludi, R., additional, Walker, A., additional, Amzulescu, M., additional, Uejima, T., additional, Fraser, A., additional, Voigt, J., additional, Esmaeilzadeh, M., additional, Maleki, M., additional, Amin, A., additional, Vakilian, F., additional, Noohi, F., additional, Ojaghi Haghighi, Z., additional, Nakhostin Davari, P., additional, Bakhshandeh Abkenar, H., additional, Rimbas, R., additional, Dulgheru, R., additional, Margulescu, A., additional, D' Asaro, M., additional, Mizzon, C., additional, Parisi, F., additional, Jung, B.-C., additional, Lee, B.-Y., additional, Kang, H.-J., additional, Kim, M., additional, Kim, Y., additional, Cho, D., additional, Park, S., additional, Hong, S., additional, Lim, D., additional, Shim, W., additional, Bellsham-Revell, H., additional, Tibby, S., additional, Bell, A. J., additional, Miller, O. I., additional, Greil, G., additional, Simpson, J. M., additional, Providencia, R. A., additional, Trigo, J., additional, Botelho, A., additional, Gomes, P., additional, Seca, L., additional, Barra, S., additional, Faustino, A., additional, Costa, G., additional, Quintal, N., additional, Leitao-Marques, A., additional, Nestaas, E., additional, Stoylen, A., additional, Fugelseth, D., additional, Mornos, C., additional, Ionac, A., additional, Petrescu, L., additional, Cozma, D., additional, Dragulescu, D., additional, Mornos, A., additional, Pescariu, S., additional, Fontana, A., additional, Abbate, M., additional, Cazzaniga, M., additional, Giannattasio, C., additional, Trocino, G., additional, Laser, K., additional, Faber, L., additional, Fischer, M., additional, Koerperich, H., additional, Kececioglu, D., additional, Elnoamany, M. F., additional, Dawood, A., additional, Elhabashy, M., additional, Khalil, Y., additional, Piriou, N., additional, Warin-Fresse, K., additional, Caza, M., additional, Fau, G., additional, Crochet, D., additional, Xhabija, N., additional, Allajbeu, I., additional, Petrela, E., additional, Heba, M., additional, Barreiro Perez, M., additional, Martin Fernandez, M., additional, Renilla Gonzalez, A., additional, Florez Munoz, J., additional, Fernandez Cimadevilla, O., additional, Alvarez Pichel, I., additional, Velasco Alonso, E., additional, Leon Duran, D., additional, Benito Martin, E., additional, Secades Gonzalez, S., additional, Gargani, L., additional, Pang, P., additional, Davis, E., additional, Schumacher, A., additional, Silva Ferreira, A., additional, Bettencourt, N., additional, Matos, P., additional, Oliveira, L., additional, Cosin-Sales, J., additional, Lopez Lereu, M., additional, Monmeneu, J., additional, Estornell, J., additional, Tsverava, M., additional, Tsverava, D., additional, Varela, A., additional, Salagianni, M., additional, Galani, I., additional, Andreakos, E., additional, Davos, C., additional, Ikonomidis, I., additional, Lekakis, J., additional, Tritakis, V., additional, Kadoglou, N., additional, Papadakis, J., additional, Trivilou, P., additional, Tzortzis, S., additional, Koukoulis, C., additional, Paraskevaidis, I., additional, Anastasiou-Nana, M., additional, Kim, G., additional, Youn, H., additional, Ibrahimi, P., additional, Bajraktari, G., additional, Jashari, F., additional, Ahmeti, A., additional, Poniku, A., additional, Haliti, E., additional, Henein, M., additional, Pezo Nikolic, B., additional, Jurin, H., additional, Lovric, D., additional, Baricevic, Z., additional, Ivanac Vranesic, I., additional, Lovric Bencic, M., additional, Ernst, A., additional, and Separovic Hanzevacki, J., additional
- Published
- 2011
- Full Text
- View/download PDF
13. P7 - 169. Resultados de la ablación epicárdica de las venas pulmonares con ultrasonidos de alta intensidad en la fibrilación auricular
- Author
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Romero Ferrer, B., Delgado Ramis, L., Fernández Gallego, C., Berastegui, E., Flores, J.B., Colli, A., Cámara Rosell, M.L., and Ruyra Baliarda, X.
- Published
- 2012
- Full Text
- View/download PDF
14. Sensitivity of quantitative precipitation forecasts to boundary layer parameterization: a flash flood case study in the Western Mediterranean.
- Author
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Zampieri, M., Malguzzi, P., Buzzi, A., Llasat, M.-C., and Ramis, L.
- Subjects
PRECIPITATION forecasting ,METEOROLOGICAL precipitation ,FLOODS ,WEATHER forecasting - Abstract
The "Montserrat-2000" severe flash flood event which occurred over Catalonia on 9 and 10 June 2000 is analyzed. Strong precipitation was generated by a mesoscale convective system associated with the development of a cyclone. The location of heavy precipitation depends on the position of the cyclone, which, in turn, is found to be very sensitive to various model characteristics and initial conditions. Numerical simulations of this case study using the hydrostatic BOLAM and the non-hydrostatic MOLOCH models are performed in order to test the effects of different formulations of the boundary layer parameterization: a modified version of the Louis (order 1) model and a custom version of the E-l (order 1.5) model. Both of them require a diagnostic formulation of the mixing length, but the use of the turbulent kinetic energy equation in the E-l model allows to represent turbulence history and non-locality effects and to formulate a more physically based mixing length. The impact of the two schemes is different in the two models. The hydrostatic model, run at 1/5 degree resolution, is less sensitive, but the quantitative precipitation forecast is in any case unsatisfactory in terms of localization and amount. Conversely, the non-hydrostatic model, run at 1/50 degree resolution, is capable of realistically simulate timing, position and amount of precipitation, with the apparently superior results obtained with the E-l parameterization model. [ABSTRACT FROM AUTHOR]
- Published
- 2005
- Full Text
- View/download PDF
15. Effect of three different bronchodilators during an exacerbation of chronic obstructive pulmonary disease
- Author
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Lloberes, P., Ramis, L., Josep Maria MONTSERRAT, Serra, J., Campistol, J., Picado, C., and Agusti-Vidal, A.
- Subjects
Pulmonary and Respiratory Medicine - Abstract
This study evaluates the effect of three different bronchodilators (beta 2-adrenergic, anticholinergic and methylxanthine) alone and in randomized sequence, during an exacerbation in thirteen patients with chronic obstructive pulmonary disease. Dose-response curves were obtained for inhaled salbutamol and inhaled ipratropium bromide. The bronchodilator effect of a perfusion of aminophylline was also assessed. When a plateau of bronchodilatation was achieved with one agent, one dose of a second bronchodilator was administered to see whether additional bronchodilation could be achieved. The increments in FEV1 and FVC were similar with the three agents. The addition of a second bronchodilator did not result in significant increments in most of the patients. In at least half of the patients the doses of salbutamol and ipratropium that produced the maximal bronchodilatation were twice that currently employed.
- Published
- 1988
- Full Text
- View/download PDF
16. Working together towards one goal: Results of the first primate census in Western Ecuador
- Author
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Cervera, L., La Torre, S., Zapata-Ríos, G., Alfonso-Cortés, F., Álvarez-Solas, S., Crowe, O., Cueva, R., La Torre, A., Duch-Latorre, I., Fernanda-Solórzano, M., Fuentes, N., Larriva, D., Maila, D., Mantilla, D., Mariscal, A., Mariscal, C., Molina, E., Morales, M., Morelos-Juárez, C., Narváez-Ruano, V., Adrián Naveda-Rodríguez, Palacios, J., Ramis, L., Rivera, E., Rubio, A., Salas, J. A., Sulca, D., Tapia, A., Toapanta, M., Troya, E., Urbina, S., Utreras, V., Velarde-Garcêz, D. A., and Veloz, O. A.
- Subjects
Hotspot ,Endangered ,Collaborative work ,Conservation ,Threats ,Survey - Abstract
Effective conservation strategies need to be created based on accurate and updated data on the distribution and conser-vation status of the species of concern. Not surprisingly, the most diverse countries which are currently facing the greater threats, tend to be those with the greatest lack of information. This is the case for Ecuador, where deforestation rates have been extremely severe, especially in the coastal region, where less than 10% of its original forest cover remains. Given the fact that primates rely on habitat connectivity for their survival, it is crucial to understand the impact of threats to their populations. To obtain data on the current distribution of the four primates known to inhabit western Ecuador, several organizations worked together to conduct the first primate census in coastal Ecuador from October 2016 to March 2017. Teams of 2−5 people walked existing trails and recorded both visual and auditory detections. We also conducted semi-structured interviews to members of local communities to complement field data. We surveyed 83 locations, and recorded 260 independent detections, along more than 300 km of trails, The four species known to occur in the region were detected: the Ecuadorian mantled howler Alouatta palliata aequatorialis; the Brown-headed Spider Monkey Ateles fusciceps; the Ecuadorian White-fronted Capuchin Cebus aequatorialis, and the Colombian White-faced Capuchin Cebus capucinus capucinus. Two other species, Aotus sp. and Saimiri sp., were mentioned during the interviews. This project is a clear example of what can be achieved when different organizations unify their efforts towards a single goal that provides the basis for future research, and suggests specific conservation measures to improve the conservation status of the primates.
17. Neumonía por citomegalovirus e insuficiencia respiratoria grave en inmunodeprimidos
- Author
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Gea, J., primary, Ramis, L., additional, Torres, A., additional, Rodriguez Roisin, R., additional, Roca, J., additional, and Agusti Vidal, A., additional
- Published
- 1985
- Full Text
- View/download PDF
18. Consensus document on the management of febrile neutropenia in paediatric haematology and oncology patients of the Spanish Society of Pediatric Infectious Diseases (SEIP) and the Spanish Society of Pediatric Hematology and Oncology (SEHOP)
- Author
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Leticia Martínez Campos, Paula Pérez-Albert, Laia Ferres Ramis, Elena María Rincón-López, Natalia Mendoza-Palomar, Pere Soler-Palacin, David Aguilera-Alonso, Institut Català de la Salut, [Martínez Campos L] Unidad de Infectología Pediátrica, Hospital Universitario Torrecárdenas, Almería, Spain. [Pérez-Albert P] Servei d'Hematologia i Oncologia Pediàtriques, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Ferres Ramis L] Servicio de Oncohematología Pediátrica, Hospital Universitario Son Espases, Palma, Mallorca, Spain. [Rincón-López EM] Sección Enfermedades Infecciosas Pediátricas, Hospital General Universitario Gregorio Marañón, Madrid, Spain. Área de Enfermedades Infecciosas Pediátricas, Centro de Investigación Biomédica en Red del Instituto de Salud Carlos III (CIBERINFEC), Madrid, Spain. [Mendoza-Palomar N] Unitat de Patologia Infecciosa i Immunodeficiències de Pediatria, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca d’Infecció i Immunitat al Pacient Pediàtric, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Soler-Palacin P] Unitat de Patologia Infecciosa i Immunodeficiències de Pediatria, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca d’Infecció i Immunitat al Pacient Pediàtric, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Pediatria, Obstetrícia i Ginecologia i de Medicina Preventiva i Salud Pública, Universitat Autònoma de Barcelona, Bellaterra, Spain, and Vall d'Hebron Barcelona Hospital Campus
- Subjects
Management of Technology and Innovation ,Neutropènia - Diagnòstic ,Decisió, Presa de ,Other subheadings::/diagnosis [Other subheadings] ,Otros calificadores::/diagnóstico [Otros calificadores] ,Malalties transmissibles ,Hemic and Lymphatic Diseases::Hematologic Diseases::Leukocyte Disorders::Leukopenia::Agranulocytosis::Neutropenia::Febrile Neutropenia [DISEASES] ,personas::Grupos de Edad::niño [DENOMINACIONES DE GRUPOS] ,Persons::Age Groups::Child [NAMED GROUPS] ,Behavior and Behavior Mechanisms::Psychology, Social::Group Processes::Consensus [PSYCHIATRY AND PSYCHOLOGY] ,conducta y mecanismos de la conducta::psicología social::procesos de grupo::consenso [PSIQUIATRÍA Y PSICOLOGÍA] ,enfermedades hematológicas y linfáticas::enfermedades hematológicas::trastornos leucocitarios::leucopenia::agranulocitosis::neutropenia::neutropenia febril [ENFERMEDADES] ,Neutropènia - Tractament - Abstract
Neoplasias; Pediatría; Infección fúngica invasiva Neoplasia; Children; Invasive fungal infection Neoplàsies; Pediatria; Infecció fúngica invasiva Febrile neutropenia is one of the main infectious complications experienced by paediatric patients with blood or solid tumours, which, despite the advances in diagnosis and treatment, are still associated with a significant morbidity and mortality. These patients have several risk factors for infection, chief of which are chemotherapy-induced neutropenia, the disruption of cutaneous and mucosal barriers and the use of intravascular devices. Early diagnosis and treatment of febrile neutropenia episodes based on the patient’s characteristics is essential in patients with blood and solid tumours to improve their outcomes. Therefore, it is important to develop protocols in order to optimise and standardise its management. In addition, the rational use of antibiotics, with careful adjustment of the duration of treatment and antimicrobial spectrum, is crucial to address the increase in antimicrobial drug resistance. The aim of this document, developed jointly by the Spanish Society of Pediatric Infectious Diseases and the Spanish Society of Pediatric Hematology and Oncology, is to provide consensus recommendations for the management of febrile neutropenia in paediatric oncology and haematology patients, including the initial evaluation, the stepwise approach to its treatment, supportive care and invasive fungal infection, which each facility then needs to adapt to the characteristics of its patients and local epidemiological trends. La neutropenia febril es una de las principales complicaciones infecciosas que sufren los pacientes pediátricos oncohematológicos, y a pesar los avances en diagnóstico y tratamiento, siguen condicionando una mortalidad y morbilidad significativa. Estos pacientes agrupan una serie de factores de riesgo de infección, donde destaca la neutropenia asociada a quimioterapia, la disrupción de barreras cutáneo-mucosas y el uso de dispositivos intravasculares. El abordaje diagnóstico y terapéutico precoz de los episodios de neutropenia febril en los pacientes oncohematológicos, ajustado a las características individuales de cada paciente, es fundamental para mejorar su pronóstico. Por ello, diseñar protocolos de abordaje, que sistematicen su atención, permite optimizar y homogeneizar su abordaje. Además, racionalizar el uso de los antimicrobianos, ajustando la duración y el espectro de los mismos, es crucial para hacer frente al incremento de resistencias a antimicrobianos. El objetivo de este documento, elaborado entre la Sociedad Española de Infectología Pediátrica y la Sociedad Española de Hematología y Oncología Pediátrica, es dar recomendaciones de consenso sobre el manejo de la neutropenia febril en el paciente oncohematológico, respecto al abordaje inicial, terapia secuencial y de soporte e infección fúngica invasiva, que cada centro debe adaptar a las características de sus pacientes y epidemiología local.
- Published
- 2023
- Full Text
- View/download PDF
19. 1 H, 15 N and 13 C backbone and side chain solution NMR assignments of the TPM domain-containing protein of the thermophilic bacterium Rhodothermus marinus.
- Author
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Pellizza L, Ramis L, Araoz IA, and Aran M
- Subjects
- Nuclear Magnetic Resonance, Biomolecular, Magnetic Resonance Spectroscopy, Protein Domains, Rhodothermus
- Abstract
The InterPro family IPR007621 TPM_phosphatase is a widely conserved family of protein domains found in prokaryotes, plants and invertebrates. Despite similar predicted protein folding, members of this family are involved in different cellular processes. In recent years, the structural and biochemical characterization of evolutionarily divergent TPM domains has shown their ability to hydrolyze phosphate groups of different substrates. However, there are still inaccurate functional annotations and uncertain relationships between the structure and function of this domain family. We here report the
1 H,13 C, and15 N backbone and sidechain resonances of the TPM domain of a predicted TPM domain-containing protein of the thermophilic bacterium Rhodothermus marinus. These data will lay the groundwork for future NMR-based investigations, contributing to a thorough comprehension of the intricate aspects governing the interplay between structure and function of TPM domains. Additionally, they will unlock opportunities to explore dynamic structural changes, providing valuable insights into the molecular mechanisms underlying the evolutionary adaptations to extreme environmental conditions within this protein family., (© 2023. The Author(s), under exclusive licence to Springer Nature B.V.)- Published
- 2023
- Full Text
- View/download PDF
20. Humoral response and neutralising capacity at 6 months post-vaccination against COVID-19 among institutionalised older adults in Argentina.
- Author
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Rodriguez PE, Silva AP, Miglietta EA, Rall P, Pascuale CA, Ballejo C, López Miranda L, Ríos AS, Ramis L, Marro J, Poncet V, Mazzitelli B, Salvatori M, Ceballos A, Gonzalez Lopez Ledesma MM, Ojeda DS, Aguirre MF, Miragaya Y, Gamarnik AV, and Rossi AH
- Subjects
- Aged, Aged, 80 and over, Antibodies, Viral, Argentina epidemiology, ChAdOx1 nCoV-19, Humans, Immunoglobulin G, Pandemics, SARS-CoV-2, Vaccination, COVID-19 epidemiology, COVID-19 prevention & control
- Abstract
The COVID-19 pandemic has particularly affected older adults residing in nursing homes, resulting in high rates of hospitalisation and death. Here, we evaluated the longitudinal humoral response and neutralising capacity in plasma samples of volunteers vaccinated with different platforms (Sputnik V, BBIBP-CorV, and AZD1222). A cohort of 851 participants, mean age 83 (60-103 years), from the province of Buenos Aires, Argentina were included. Sequential plasma samples were taken at different time points after vaccination. After completing the vaccination schedule, infection-naïve volunteers who received either Sputnik V or AZD1222 exhibited significantly higher specific anti-Spike IgG titers than those who received BBIBP-CorV. Strong correlation between anti-Spike IgG titers and neutralising activity levels was evidenced at all times studied (rho=0.7 a 0.9). Previous exposure to SARS-CoV-2 and age <80 years were both associated with higher specific antibody levels. No differences in neutralising capacity were observed for the infection-naïve participants in either gender or age group. Similar to anti-Spike IgG titers, neutralising capacity decreased 3 to 9-fold at 6 months after initial vaccination for all platforms. Neutralising capacity against Omicron was between 10-58 fold lower compared to ancestral B.1 for all vaccine platforms at 21 days post dose 2 and 180 days post dose 1. This work provides evidence about the humoral response and neutralising capacity elicited by vaccination of a vulnerable elderly population. This data could be useful for pandemic management in defining public health policies, highlighting the need to apply reinforcements after a complete vaccination schedule., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Rodriguez, Silva, Miglietta, Rall, Pascuale, Ballejo, López Miranda, Ríos, Ramis, Marro, Poncet, Mazzitelli, Salvatori, Ceballos, Gonzalez Lopez Ledesma, Ojeda, Aguirre, Miragaya, Gamarnik, Rossi, Laboratorio SeVa Group and PAMI Group.)
- Published
- 2022
- Full Text
- View/download PDF
21. The impact of frailty in aortic valve surgery.
- Author
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Berastegui Garcia E, Camara Rosell ML, Moret Ruiz E, Casas Garcia I, Badia Gamarra S, Fernandez Gallego C, Delgado Ramis L, Julia Almill I, Llorens Ferrer A, Romero Ferrer B, Bayes Genis A, and Muñoz Guijosa C
- Subjects
- Aged, Aortic Valve surgery, Frail Elderly, Geriatric Assessment, Humans, Male, Prospective Studies, Quality of Life, Risk Assessment, Risk Factors, Treatment Outcome, Aortic Valve Stenosis surgery, Frailty diagnosis, Transcatheter Aortic Valve Replacement
- Abstract
Background: Frailty is a geriatric syndrome that diminishes potential functional recovery after any surgical procedure. Preoperative surgical risk assessment is crucial to calibrate the risk and benefit of cardiac surgery. The aim of this study was to test usefulness of FRAIL Scale and other surgical-risk-scales and individual features of frailty in cardiac aortic valve surgery., Methods: Prospective study. From May-2014 to February-2016, we collected 200 patients who underwent aortic valve replacement, either surgically or transcatheter. At 1-year follow-up, quality of life measurements were recorded using the EQ-5D (EuroQol). Univariate and multivariate analyses correlated preoperative condition, features of frailty and predicted risk scores with mortality, morbidity and quality of life at 1 year of follow-up., Results: Mean age 78.2y, 56%male. Mean-preoperative-scores: FRAIL scale 1.5(SD 1.02), STS 2.9(SD 1.13), BI 93.8(SD 7.3), ESlog I 12.8(SD 8.5) and GS 7.3 s (SD 1.9). Morbidity at discharge, 6 m and 1 year was 51, 14 and 28%. Mortality 4%. Survival at 6 m/ 1-y was 97% / 88%. Complication-rate was higher in TAVI group due to-vascular complications. Renal dysfunction, anemia, social dependence and GS slower than 7 s were associated with morbidity. On multivariate analysis adjusted STS, BI and GS speed were statistically significant. Quality of life at 1-year follow-up adjusted for age and prosthesis type showed a significant association with STS and FRAIL scale scores., Conclusions: Frailty increases surgical risk and is associated with higher morbidity. Preoperative GS slower 7 s, and STS and FRAIL scale scores seem to be reliable predictors of quality of life at 1-year follow-up.
- Published
- 2020
- Full Text
- View/download PDF
22. [Gastric adenocarcinoma associated with Helicobacter pylori in the pediatric setting].
- Author
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Riera Llodrá JM, Rosell Camps A, Ferrés Ramis L, Guibelalde del Castillo M, Zibetti S, and Amengual Antich I
- Subjects
- Adenocarcinoma diagnosis, Child, Helicobacter Infections diagnosis, Humans, Male, Stomach Neoplasms diagnosis, Adenocarcinoma microbiology, Helicobacter Infections complications, Helicobacter pylori, Stomach Neoplasms microbiology
- Published
- 2015
23. Histamine intolerance as a cause of chronic digestive complaints in pediatric patients.
- Author
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Rosell-Camps A, Zibetti S, Pérez-Esteban G, Vila-Vidal M, Ferrés-Ramis L, and García-Teresa-García E
- Subjects
- Child, Diet, Food Hypersensitivity, Humans, Retrospective Studies, Amine Oxidase (Copper-Containing), Histamine
- Abstract
Introduction: histamine intolerance (HI) is a poorly described disease in gastroenterology that may present with predominant digestive complaints. The goals of this study include a report of two cases diagnosed in a pediatric gastroenterology clinic., Material and Methods: observational, retrospective study of patients diagnosed with HI from September 2010 to December 2011 at the pediatric gastroenterology clinic of a tertiary hospital.They were deemed to have a diagnosis of HI in the presence of 2 or more characteristic digestive complaints, decreased diamino oxidase (DAO) levels and/or response to a low histamine diet with negative IgE-mediated food allergy tests., Results: sixteen patients were diagnosed. Males predominated versus females (11/5). Mean age at symptom onset was 4 years (6 months vs. 13 years and 6 months) and mean age at diagnosis was 6 years and 6 months (17 months vs. 13 years and 11 months), with an interval of 2 years and 1 month between symptom onset and diagnosis (5 months vs. 4 years). Predominant symptoms included diffuse abdominal pain (16/16), intermittent diarrhea (10/16), headache (5/16), intermittent vomiting (4/16), and skin rash (2/16). The diagnosis was established by measuring plasma diamino oxidase levels, which were below 10 kU/L (normal > 10 kU/L) in 14 cases, and symptom clearance on initiating a low histamine diet. In two patients DAO levels were above 10 kU/L but responded to diet. Treatment was based on a diet low in histamine-contaning food, and antihistamines H1 y H2 had to be added for two cases., Conclusions: histamine intolerance is a little known disease with a potentially relevant incidence. Predominant complaints include diffuse abdominal pain, diarrhea, headache, and chronic intermittent vomiting. Its diagnosis is based on clinical suspicion, plasma DAO measurement, and response to a low histamine diet. Management with the latter provides immediate improvement.
- Published
- 2013
- Full Text
- View/download PDF
24. [Traumatic rupture of tricuspid valve: report of 3 cases].
- Author
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Delgado Ramis LJ, Montiel J, Arís J, and Caralps JM
- Subjects
- Adolescent, Adult, Humans, Male, Rupture, Tricuspid Valve surgery, Wounds and Injuries diagnosis, Tricuspid Valve injuries
- Abstract
Tricuspide valve lesions due to non-penetrating trauma are rare and their diagnosis is difficult. Nevertheless, over 100 cases of post-traumatic valve regurgitation have been described in the last 35 years. We present 3 such cases diagnosed and operated at our center in the last 8 years.
- Published
- 2000
- Full Text
- View/download PDF
25. [The unequal clinical profile, quality of life and hospital mortality in patients undergoing aortocoronary bypass in the public and private centers of Catalonia. The CIRCORCA Study].
- Author
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Permanyer Miralda G, Brotons Cuixart C, Ribera Solé A, Cascant Castelló P, Moral Peláez I, Pons JM, Alonso Caballero J, Mallol Kirchner A, Barthe Carrera J, Martínez Useros C, Cardona Burrull M, Delgado Ramis L, and Romero Ferrer B
- Subjects
- Aged, Cardiac Care Facilities statistics & numerical data, Coronary Artery Bypass statistics & numerical data, Coronary Disease mortality, Coronary Disease surgery, Female, Follow-Up Studies, Hospitals, Private statistics & numerical data, Hospitals, Public statistics & numerical data, Humans, Male, Middle Aged, Risk Factors, Spain epidemiology, Surveys and Questionnaires, Coronary Artery Bypass mortality, Coronary Disease diagnosis, Hospital Mortality, Quality of Life
- Abstract
Introduction and Aims: The influence of the type of health care funding and management of hospital centres on hospital mortality in coronary artery bypass surgery (CABG) has not been analyzed in detail. We therefore assessed clinical and quality of life preoperative profiles and in-hospital mortality in public and private patients undergoing coronary bypass surgery in Catalonia., Methods: Clinical questionnaires, Duke Activity Status Index (DASI) and SF-36 were preoperatively administered to all patients undergoing first coronary bypass surgery without associated procedures in Catalonia between November 1996-June 1997. In-hospital morbidity and mortality were recorded., Results: Predictors of in-hospital death, including DASI, SF-36 and comorbidity scores, were significantly worse in public than in private patients. In-hospital mortality rate was more than ten times greater in public than in private patients (8.2% vs 0.7%; p < 0.001). Multivariate analysis identified private funding of health care, among others, as an independent predictor of in-hospital survival. Non evidence-based indications for surgery were significantly more common in private than in public patients (6% vs 0.7%, p < 0.001)., Conclusions: a) In catalonia, the risk profile of public patients undergoing coronary bypass surgery was significantly higher than that of private patients, accounting, at least in part, for a remarkable mortality difference; b) non evidence-based indications for surgery were more common in private than in public patients; c) these unequal patterns raise questions about the adequacy of care and referral patterns in both private and public sectors.
- Published
- 1998
26. Pulmonary gas exchange in severe chronic asthma. Response to 100% oxygen and salbutamol.
- Author
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Ballester E, Roca J, Ramis L, Wagner PD, and Rodriguez-Roisin R
- Subjects
- Administration, Inhalation, Adult, Aged, Albuterol administration & dosage, Asthma blood, Blood Gas Analysis, Chronic Disease, Hemodynamics drug effects, Humans, Middle Aged, Oxygen administration & dosage, Reference Values, Spirometry, Ventilation-Perfusion Ratio drug effects, Albuterol pharmacology, Asthma physiopathology, Oxygen pharmacology, Pulmonary Gas Exchange drug effects
- Abstract
Ventilation-perfusion (VA/Q) inequality has been evaluated using the multiple inert gas technique in nine nonsmoking patients (mean +/- SD, age 56 +/- 10 yr) with stable, severe, chronic asthma (partially reversible airway obstruction; baseline FEV1, 39 +/- 10% predicted) before and during 100% O2 breathing and then 15 min after three puffs (300 micrograms) of inhaled salbutamol. The aim of this study was to investigate whether this type of asthma was associated with a different pattern of VA/Q inequality from that observed in acute episodes and in particular to determine whether the VA/Q pattern was fixed or could be altered by bronchodilator agents or O2 breathing. The predominant pattern of VA/Q distribution was broad and unimodal but without shunt (VA/Q = 0) or low VA/Q areas (VA/Q less than 0.1 to greater than 0.005). The amount of VA/Q inequality as assessed by the dispersion of the distribution of pulmonary bloodflow (log SDQ) was not great (log SDQ, 0.77 +/- 0.09), and no correlation was found with the degree of airway obstruction, PaO2 or AaPO2. During 100% O2 breathing, VA/Q inequality worsened (from log SDQ of 0.77 +/- 0.09 to 1.11 +/- 0.21, p = 0.01) with an increase in the perfusion of low VA/Q units (from 0.43 +/- 0.66% to 6.3 +/- 6.5%, p = 0.02) but still no development of shunt. This suggests the presence of hypoxic pulmonary vasoconstriction breathing air, possibly contributing to the preservation of VA/Q relationships.(ABSTRACT TRUNCATED AT 250 WORDS)
- Published
- 1990
- Full Text
- View/download PDF
27. Serial relationships between ventilation-perfusion inequality and spirometry in acute severe asthma requiring hospitalization.
- Author
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Roca J, Ramis L, Rodriguez-Roisin R, Ballester E, Montserrat JM, and Wagner PD
- Subjects
- Acute Disease, Adult, Asthma blood, Female, Forced Expiratory Volume, Hospitalization, Humans, Male, Maximal Midexpiratory Flow Rate, Middle Aged, Oxygen blood, Peak Expiratory Flow Rate, Pulmonary Circulation, Pulmonary Gas Exchange, Asthma physiopathology, Spirometry, Ventilation-Perfusion Ratio
- Abstract
Patterns of VA/Q distribution and their relationship to spirometric indices were studied in 10 patients with acute severe asthma requiring hospitalization (7 women and 3 men 41.0 +/- 5.6 yr of age, mean +/- SEM) on admission and during subsequent recovery. On admission, all patients received the standard therapeutic regimen for our hospital. Spirometry and essentially noninvasive multiple inert gas elimination measurements were obtained serially, approximately once every day, whereas conventional arterial blood gases were determined every 3 days. On admission, all patients showed severe air-flow obstruction (FEV1/FVC% = 34.1 +/- 4.3%) and moderate to severe hypoxemia without CO2 retention (PaO2 = 50.5 +/- 2.6 mm Hg; PaCO2 = 37.1 +/- 2.4 mm Hg; AaPO2 = 53.7 +/- 3.0 mm Hg). Nine of the 10 patients showed bimodal blood flow distributions (dispersion of blood flow distribution, log SD Q = 1.34 +/- 0.11; normal range, 0.3 to 0.6) with only small amounts of shunt (1.09 +/- 0.8%). However, no significant interindividual correlations were observed between maximal expiratory flow rates (FEV1 and FEF25(-75) and log SD Q (r2 = 0.14 and 0.006, respectively). This lack of correlation persisted throughout hospitalization. Despite both clinical and spirometric improvement in all patients, there was simultaneous improvement in VA/Q matching in only one patient. Statistically significant negative correlations between maximal expiratory flow rates and gas exchange did develop toward the end of the study (Weeks 3 and 4 after discharge) when maximal recovery of physiologic changes associated with the acute asthma attack was achieved.(ABSTRACT TRUNCATED AT 250 WORDS)
- Published
- 1988
- Full Text
- View/download PDF
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