Search

Introduction: Previous studies have been conducted on the effects of exposure of industrial workers to high levels of noise and their association with mental health or exposure of people to harmful levels of environmental noise. In this study, we investigated the association between moderate noise levels and the symptoms of depression, anxiety, and stress in non-industrial workers. Material and Methods: This study is a Cross-Sectional study that was conducted using the enrollment phase data of the Tehran University of Medical Sciences Cohort (TEC) study. The study population consisted of 3899 workers of Tehran University of Medical Sciences who were employed in seven occupational groups of the university, Office Workers, Healthcare workers, technical personnel, services workers, security guards, and radiology-radiation units. Exposure to moderate noise level was examined using the Leq10min index, and the Depression Anxiety Stress Scales were examined on the mentioned population by DASS-42 questionnaires. Results: The results showed that the prevalence of severe to very severe symptoms of depression, anxiety and stress were 8.2, 7.9, and 11% respectively. Also, it was observed that 14.5% of the participants of the study were exposed to noises of more than 70 dB(A). Furthermore, the results indicated that the highest average noise was equal to 71.3 dB(A) for the technical staff group, and the lowest value with an average of 59.1 dB(A) was recorded for the office workers group. The symptoms of severe to very severe depression was associated with exposure to noises above 70 dB(A) (OR:5.22) anxiety (OR:1.16), stress (OR:1.17) and socioeconomic status (OR:1.84). The severe to very severe anxiety was associated with stress (OR: 1.25). On the other hand, the symptoms of severe to very severe stress was associated with variables of age (OR:0.99), gender (OR:0.46), socioeconomic status (OR:1.52), having job management position (OR:0.81) and having healthcare working job (OR:0.65). Conclusion: Regarding the obtained results of the present study, it was concluded that exposure to moderate noise levels had positive and significant association with depression in non-industrial workers. In non-industrial work environments, exposure to moderate noise levels is and can be independently associated with depression.

Introduction: Musculoskeletal disorders (MSDs) are prevalent in work settings and are associated with high rate of prevalence and costs. Musculoskeletal conditions have multifaceted nature, and occupational factors play an important role in their development. The aim of this study was to identify the risk factors of work-related musculoskeletal disorders in the working population in Iran during 2000 to 2015. Material and Methods: Using the appropriate search terms, articles published in the journals, student thesis, and those presented at the conferences were searched through authentic English databases (Google Scholar, Scopus, PubMed) and Farsi ones (Magiran, SID, IranMedex, Irandoc). Following removal of duplicate citations and irrelevant studies, the full texts of the remaining publications were prepared and assessed for more detail. Results: Perceived discomfort in low back region obtained the highest score in workers of industrial, administrative, service, and agricultural settings. However, in the handicraft and educational groups, the highest percentage of discomfort was belonged to neck (66.7%). Findings showed that the most commonly used techniques for evaluation of musculoskeletal disorders and risk factors were, respectively, Nordic questionnaire (NMQ) (76%) and REBA (13.9%). Moreover, all identified risk factors were classified into eleven groups including: biomechanical, work environment design, tools, equipment, temporal aspects of job design, job content, organizational aspects, economic and financial issues, social aspects, individual characteristics, and training. Conclusion: Overall, a wide range of risk factors reported in the previous studies were categorized in the present review. The results are suggested to be considered by managers and decision makers as a framework to take measures for controlling musculoskeletal disorders to accomplish the goal of ergonomics, which is productivity and well-being.

Abstract Background In this study, the association between the social determinants of health (SDH) as well as other health risk factors and outcomes will be evaluated at different socioeconomic layers. Methods/design This is a prospective cohort study that was launched in January 2018 on Tehran University of Medical Sciences’ employees. The initial enrolment phase will continue up to March 2021, or until a sample size of 5500 is reached. In addition to annual phone-calls, the participants will be followed thrice at 5-year intervals. Data are collected through blood and urine samples, complete physical examination, anthropometric evaluation, and the completion of questionnaires related to SDH, such as socioeconomic status and social capital, history of diseases, lifestyle (including, nutrition, physical activity, cigarette and hookah smoking), occupational exposures (including psychosocial factors at work and work-family conflicts), and different aspects of physical, mental and occupational health as health outcomes. The association between independent variables and health (objective or subjective) are examined using multiple models and by controlling the confounding effects. Moreover, the trend in lifestyle changes and its impact on health are evaluated. Discussion Our study will explore the key social determinants as well as other factors including socioeconomic status and social capital, history of diseases, lifestyle and occupational exposures that affect health. This will provide social and occupational health decision-makers and stakeholders with new and valuable evidence in an era in which we are witnessing huge changes in lifestyle.

Background: Violence against medical assistants (residents) by colleagues is a serious problem at educational hospitals that has not been sufficiently examined. The present study was conducted to determine the prevalence, risk factors, and types of violence perpetrated by colleagues against medical assistants. Methods: In a cross-sectional study conducted at two large tertiary referral educational hospitals, the study questionnaires were distributed among 480 healthcare professionals to investigate their experiences of violence. Results: Of 280 responders, 162 residents (57.9%) reported a history of violence or aggression. Of these, nearly 50% had experienced pure psychological violence, and 16.7% had been physically abused. The prevalence of victimization was high among the residents of the neurosurgery, orthopedic, and obstetric departments (90%, 88%, and 85%, respectively). Conclusion: Harassment experience was more common among the surgical residents than the internal medicine residents because of the former’s high level of work stress. Senior residents or fellowship residents were the main abusers. Losing professional self-esteem, decreasing job satisfaction, and dropping out of school were the main adverse outcomes of violence experienced by the victims.

Introduction: Previous studies confirm direct and indirect costs of low back pain in occupational settings. However, there is no systematic study of the risk factors for low back pain in different occupations; while planning and allocating resources requires comprehensive knowledge at the national and regional levels in order to control and manage low back pain. Therefore, the aim of this study was to identify risk factors of low back pain in Iranian workers during the years 2000 to 2015. Methods: Published journal papers, articles presented at the congresses and student thesis reports were systematically reviewed. Abstracts were extracted using appropriate keywords and authentic English-language (Google Scholar, Scopus, and PubMed) and Farsi (Magiran, SID, IranMedex, and Irandoc) databases. Following quality assessment of the selected publications, the full texts of the related ones were reviewed. Results: In 150 eligible studies, the mean prevalence of low back pain in the last 12 months was 48.77. Nordic questionnaire was the most commonly used technique for assessing back pain, and RULA and REBA were the most commonly used method for determining risk factors. All risk factors were categorized into nine groups: biomechanical, workplace design, tools and equipment, environmental, temporal aspects of job design, job content, organizational aspects, personal characteristics, and training. Conclusion: According to the findings, about half of the workers in Iran experienced low back pain. Considering the widespread risk factors and the high prevalence of low back pain among various occupational groups, it is suggested that appropriate measures be taken based on the findings of this study.

Introduction: The Surgical Safety Checklist has been introduced by the World Health Organization (WHO) as a tool for reducing medical errors. Reviewing the results of the checklist application indicates significant reduction in mortality and complications in surgery. Thus, this study aimed to customize and validate surgical safety checklist in order to complying with the surgical protocol in Iran. Material and Method: In this cross-sectional and descriptive study, the WHO Safety Surgery Checklist was first translated. Next, through interviews with specialists and direct observation of activities, those tasks that were susceptible to the incident, identified, prioritized and analyzed using Hierarchical Task Analysis (HTA) and the results presented in form of HTA charts. Then, using Tabulate Task Analysis (TTA) and based on the recommendation and modification commented by expert panel, some questions added to the checklist and a customized version of the Surgical Safety Checklist was provided. Hence, the faced validity, content validity and reliability of the checklist have been evaluated. Result: In the surgery, four major tasks identified for analyzing using the HTA chart. Accordingly, 41 subtasks obtained and analyzed by TTA. The Lavashe method was used to determine the content validity ratio (CVR) and the content validity index (CVI). The question from the checklist, in which, CVI was less than 0.79, modified and replaced with appropriate question. Also, the scores for 3 questions were less than 0.49, and they were removed from the checklist due to the low CVR score. In the reliability assessment, the intra-observer method is used, and the Kappa coefficient obtained was acceptable and it was higher than 0.6, which confirmed the validity of the checklist. Conclusion: In this study, the surgical safety checklist customized in terms of content validity and reliability, in a field study. Considering the compliance of the checklist items with the surgical protocol in Iran, we hope to use it to improve the quality of teamwork and reduce the complications and mortality caused by surgical errors

Background: Absence from work for health reasons is known as “sickness absenteeism”. Frequent sick leave is a major concern to any organization, especially hospitals. Objective: This study analyzed the extent and causes of sickness absenteeism in a teaching hospital and evaluated its corelation with demographic and occupational factors. Methods: In a cross-sectional study, data was extracted from computerized records regarding sickness absenteeism of healthcare workers (HCWs) in the Occupational Health Department of a teaching hospital in Tehran. Studied variables included demographic characteristics, occupational factors, and causes of sickness absenteeism. The sickness absence rate (SAR) and absence frequency rate (AFR) in the study period were calculated. Chi-square and Mann-Whitney tests were used for the comparison of categorical and quantitative variables, respectively. Results: In the current study, SAR and AFR were 0.011 and 0.68, respectively. Job type was the only factor that had a significant correlation with sickness absenteeism. The major disease-causing sicknesses were flu (21%) and musculoskeletal disorders (18.9%). Conclusion: A significant relationship was found between the nursing group and sickness absence episodes. Flu, musculoskeletal disorders, and infectious diseases were the most frequent causes of sickness absence. Based on these findings, it can be concluded that factors such as availability of the flu vaccine and providing principles of personal protection and infection control can reduce sickness absence due to infectious disease.

Background: Exposure to noise can induce hearing loss. Thus noise induced hearing loss is one of the main concerns in interventional study on health effect of noise exposure. We analyzed pre and post exposure audiometeries of volunteers in a clinical trial study that we conducted for effect of noise exposure on cardiovascular system. Methods: In a clinical trial study, 100 healthy, 20-40 aged, volunteer men exposed to 90 dB noise for 30 minute. We take pre and post exposure pure tone audiometric test from all of subjects. Results: Mean of PTA among 100 subjects was reduced 0.72 dB in right ear and 0.44 dB in left ear. Mean of hearing threshold in each of 250, 500, 3000, 4000 and 8000HZ frequencies rise in left ear and was reduced in all of other frequencies in right and left ear. Conclusion: Results of our study indicated that short term exposure to 90 dB noise in interventional studies cannot produce clinically significant hearing loss.

Introduction: Quality of Work Life (QWL) is a new form of job satisfaction which involves ones feelings about all aspects of their job. The aim of this study was to assess the psychometric properties of the Persian version of WRQoL-2 questionnaire for use in the nursing community. Material and Method: In this study, backward translation method was used in order to verify the linguistics stability. Then, the cross-sectional study was conducted among 270 nurses working in a hospital, affiliated to Tehran University of Medical Sciences. Reliability and construct validity was investigated using test-retest and factor analysis, respectively. In addition, discriminant validity was assessed by comparing QWL mean scores of nurses satisfied with their salary and those who were dissatisfied. Result: Regarding the reliability, it was observed that the repeatability coefficient were at an acceptable level for all dimensions of the WRQoL-2questionnaire. According to factor analysis, six components were identified with some questions in different groups compared to the original questionnaire. Considering discriminant validity, all components, except Stress at Work, obtained P-value less than 0.05. Conclusion: Based on the acceptable level of reliability and validity of the WRQoL-2 questionnaire, use the questionnaire to assess the quality of work life of nurses is recommended.

Objectives: Identifying factors predictive of early return to work in patients who underwent a coronary artery bypass graft surgery (CABG). Material and Methods: Two hundred twenty-six working patients who volunteered and underwent a primary coronary artery bypass surgery between September 2013 and May 2014 were selected for the study and followed up for 6 months. Predictors of early return to work (RTW) (within 2 months) were analyzed from variables in a prospectively collected database and the 36-Item Short Form Health Survey (SF-36) questionnaire carried out in the hospital and rehabilitation center as well as from the follow-up performed via the phone. Results: One hundred and two (45.1%) and 155 (68.9%) patients returned to work within 2 and 3 months after the surgery, respectively. Furthermore, 196 patients (87.1%) returned to work within 6 months after the surgery. In the univariate analysis, demographic or socioeconomic factors (such as age, level of education, income), occupational factors (such as occupation type, working hours per week, duration of the preoperative absence from work), psychological factors (such as a patient’s concern about adverse health effects of RTW, feeling depressed, a patient’s attitude towards his/her ability to RTW and a patient’s perception of his/her job stress level) and medical factors (such as serum troponin T and creatine kinase MB (CKMB) level, pump time in surgery, co-surgery and dyslipidemia history) had a statistically significant correlation with early return to work. The patients who early returned to work had significantly higher scores in 3 domains on the SF-36 questionnaire (used for assessing the patients’ quality of life), compared to those who did not return to work early (including physical functioning, role limitations due to physical health and pain). Conclusions: In the present study we identified 4 new medical factors that could be used as predictors of early return to work after CABG. These factors are: normal serum troponin T level, shorter pump time in surgery, normal mean arterial pressure (MAP) before the surgery and higher serum magnesium (Mg) levels. Int J Occup Med Environ Health 2016;29(6):947–957

Background: There are few research studies evaluating the significance of low back pain (LBP) in Iran, even though the majority of locally published surveys are written in the Persian language. In the present review study, we aimed at appraising published articles related to the burden of LBP and its divergence among different jobs. Methods: A comprehensive search was conducted in all accessible national and international electronic databases from 1948 to mid-2012. The international electronic databases were MEDLINE (PubMed), Web of Sciences, Google Scholar, Scopus, CINAHL, and the Iranian equivalents were SID, IRANDOC, IranMedex, and Magiran. The main search terms were musculoskeletal disorders, musculoskeletal symptoms, low back pain, back pain, and Iran. All keywords were searched electronically by three Boolean operators. The inclusion criteria were age ≥10 years, study focus on LBP prevalence, inclusion of both genders, and no limitation to the study design. A dedicated STROBE questionnaire was developed as a critical appraisal tool and the quality of the identified literature was examined according to the 5-point Linker scale. Articles scoring ≥3 on the Linker scale were appraised. Each literature was screened by four reviewers independently and possible disagreements were streamlined in a joint review meeting. The extracted data were entered into a dedicated table using Microsoft Office Excel program. Data were analyzed for homogeneity using the STATA software (version 11). Results: Of the 51 articles that were included in the present review study, 35 articles reported 1-year LBP with Nordic questionnaire and 3 articles reported point prevalence of LBP. The calculated global prevalence of 1-year LBP in workers was 25% and LBP was the most prevalent issue among health care workers. There was no association between the prevalence of LBP and job classification among workers. Conclusion: LBP is the most common issue among health care workers. It is recommended that future research should focus on this job category for investigating LBP prevalence. This allows parameters that increase the frequency of LBP to be assessed and subsequently permits the reduction or elimination of such factors.

Introduction: Absenteeism is one of the challenging issues in managing human resources. Many social, economic and personal factors may affect sickness absence. We studied effects of some personal factors on sickness absence in a governmental organization. Methods: In a cross-sectional study, we invited all of white collar workers of one governmental organization to participate in this study. Data regarding personal factors collected for volunteers and combined with long-term sickness absence data which extracted from sickness absence certification files. Results: A total of 527 workers, including 408 males and 119 females participated in our study. Of these 527 participants, 70 (13.3%) had a history of long-term sickness absence in the past three years. Sickness absence spells were significantly associated with female sex, smoking, less than three person kinship responsibility, chronic disease and poor self-rated general health, in regression analysis. Working days lost due to sickness absence were significantly associated with female sex, smoking and chronic disease, in regression analysis. Conclusion: Diseases are not the sole cause of sickness absence and other personal factors may play a significant role on making a decision to withdraw from the workplace.

Spirometry is a tool for screening and early diagnosis of harms caused by occupational respiratory exposures. Since spirometry results largely depend on the spirometry method, their credibility and acceptability may vary. Accordingly, this cross-sectional study was conducted to assess the quality of spirometry procedures and reports in the periodic examinations of workers in an industry. The study assessed a total number of 506 recorded spirometry test results related to the periodic examinations of 190 workers in an industry between 2005 and 2015. Each test was assessed in terms of ATS (American Thoracic Society) standards and the quality of reporting, and the obtained results were compared with the spirometry tests conducted by the research team. The most common error in performing these tests was the failure to allow for the 6-second exhalation (in 70% of the cases). After removing the effect of increasing age, it was found that the reported FVC (Forced Vital Capacity) and FEV1 (Forced Expiratory Volume in one second ) in these tests were different from those in the standard spirometry tests performed by the research team by 5% in more than half of the cases and by more than 10% in a quarter of the cases. The results revealed the poor quality of the spirometry tests in the periodic examinations of the workers. Therefore, it is recommended to train the spirometry operators and monitor more vigorously the quality of spirometry tests in the occupational examinations.

Workplace violence is frequent in medical specialty training setting in Iran. Therefore, development and implementation of workplace violence prevention guideline in this setting is a necessity. Workplace violence has become an issue of increasing concern. Residents are often the first physician that patients will meet them. We conducted this study to evaluate workplace violence against medical residents in Iran. In a cross-sectional questionnaire-based study, we asked 1107 medical residents about violence exposure during past 12 months. Overall, 892 of residents (2010-2011) participated in our study (response rate = 80.6%). Prevalence of experience of psychological and physical violence at work was obtained 63.7% and 19.7%, respectively. Sex, residency program, managerial support and year of education had independent effect on violence at work. Our results showed high frequency of violence at work against Iranian medical residents and indicated importance of development and implementation of workplace violence prevention guideline in medical specialty training setting in Iran.

Background: Cancer is the third cause of death in Iran. Approximately 5-10% of all human cancers are thought to be caused by occupational exposure to carcinogens. Dif-fuse mesotheliomas of the peritoneum and pleura are considered "signal tumors," or pa-thognomonic of exposure to asbestos. There is also evidence that nonasbestos agents can induce malignant mesotheliomas. So, we need to study the history of exposure to asbestos in patients suffering from mesothelima to determine relationship between them in Iran, especially in occupational settings. Methods: We received the data of 272 mesothelioma's patients having been registered in 1385 to 1389 in Cancer Bureau, in Ministry of Health. One hundred fifty four of them had telephone number. Finally we could interview with 60 families and gathered data of patient's history of occupation, cigarette smoking and residence place interred in the designed questionnaire. Then we brought out the variants of age, sex, the province of birth place and the involved organs from the data of Cancer Bureau. Analysis of frequency of variants was carried out and compared once in 272 patients being registered in Cancer Bureau and then in the interviewed 60 patients. Results: Distribution of age, sex, the province of birth and living place and the involved organ were similar in cancer registry's data and the interviewed patients. Distribution of cigarette smoking and exposure to asbestos in the interviewed patients were 28% and 63% respectively. Occupational distribution of interviewed patients consisted of con-struction workers 20%, oil company employees 13.3%, administrative staff 8.3% and drivers 6.7%. Conclusion: The results of our study specified the jobs with high risks of exposure to asbestos and approved the relationship between the exposure to asbestos and the inci-dence of mesothelioma in Iran, according to researches in other countries. So the con-sumption of asbestos in Iran, like 20 other countries in the world is necessary to be banned.

Cardiovascular adverse effects are interesting aspects of occupational noise exposure. One possible mechanism of these effects is an alternation in hypothalamic-pituitary-adrenal axis. Our aim was to measure salivary cortisol response to relatively high-intensity noise exposure in a controlled randomized trial study. We exposed 50 male volunteers to 90 dBA noise for 20 minutes and compared their level of salivary cortisol with 50 non-exposed controls. Salivary samples obtained before and after exposure. Before intervention means (SD) salivary cortisol level were 3.24 (0.47)ng/ml and 3.25 (0.41)ng/ml for exposed and non-exposed groups respectively. Mean salivary cortisol level increased to 4.17 ng/mlafter intervention in exposure group. This increment was statistically significant (P=0.00). Mean salivary cortisol level of the non-exposed group had statistically non-significant decrement after this period (0.2 ng/ml). The difference between salivary cortisol level of non-exposed and exposed groups after the intervention was statistically significant. Noise exposure may affect the hypothalamic-pituitary-adrenal axis activity, and this may be one of the mechanisms of noise exposure cardiovascular effects.

Firefighting is extremely strenuous and physically demanding work and involves ability to cope with emergency life-or-death situations. Because of the high physical demands of firefighting, successful job performance and minimizing of morbidity and mortality depends on fitness for duty. The firefighting department of Tehran does not perform periodic medical assessment for firefighters. The aim of this study was to evaluate medical fitness among firefighters in Tehran. In this cross sectional study we examined 147 firefighters. Medical and occupational history obtained by interview, then we performed physical examination, blood tests, ECG, spirometry and audiometry. Then results compared with guidelines for firefighters in the USA, Australia and the United Kingdom. Seven percent of our participants had a kind of pulmonary dysfunction and 25% had some degrees of hearing loss. A considerable percent of them had modifiable coronary heart disease risk factors. Thirteen participitants were unfit for this job that among them; ten firefighters were unfit based on vision capability, one case due to hypertention and two cases because of pulmonary dysfunction. Because of hazardouse nature of firefighting; preplacement, periodic medical evaluations and assesment of fitness for firefighters in Iran is highly recommended. Establishment of fitness criteria for firefighters in Iran is necessery to perform assigned functions safely.

Abdominal wall hernia is common but reliable scientific data about its work relatedness is very limited and inconsistent. In this paper, a less common type of abdominal wall hernia in a 30 year old male worker is presented with recurrence after first surgery when he returned to work. In contrast with almost all kinds of hernia, a lifelong limitation for heavy lifting was recommended. It seems that contrary to popular belief, work relatedness of abdominal wall hernia is seriously doubtful, although conclusive evidences are not enough. It is preferable to make decisions cautiously for return to heavy duties of work after surgery of large umbilical, umbilical & epigastric or incisional hernia, while avoiding recommendations for long days off work after surgery of any hernia.

Background: One of the serious occupational concerns in health care workers (HCWs) is exposure to blood/body fluids that can transmit blood borne pathogens such as human immunodeficiency virus and hepatitis B and C viruses. We are reporting the effects of training course and surveillance on the rate of needle stick injuries (NSIs) among HCWs at an educational hospital in Iran. Aims: To evaluate the effects of training course on the rate of NSIs and its reporting. Methods: We selected two hospitals (A&B) based on their similarities in wards and facilities then asked the managers of these two hospitals to participate in our study. We established a new occupational health center and conducted a training course at hospital A on 2010 and compared it with control group (hospital B). The data from 2009 to 2011 was collected, analyzed to compare pre and post intervention rates. Results: During study period nurses sustained the highest number of injuries (hospital A: n=80; 66.1% and hospital B: n=64; 35.4%). The incidence rate of NSIs in hospital A was 7.16 NSI/100FTE/YEAR before the intervention which was increased to 12.06 after the intervention. In hospital B this rate was 6.05 during three years. Conclusions: The study revealed remarkable increase in the incidence rate of NSIs after the intervention. This is being achieved by meticulous surveillance, training course and improving awareness

Background: Firefighting is a unique job with contradictious demands that expose firefighters to many well documented causal factors of sleep debt, but no studies in Iran and only a few worldwide studies have investigated their sleep quality while sleep problems may lead to catastrophes especially in critical service workers. The aim of this study is to evaluate sleep quality and its related factors among a sample of professional Iranian firefighters. Methods: Using simple random sampling method in a cross-sectional study, 427 personnel of fire and rescue service were invited. They completed the Persian version of Pittsburgh Sleep Quality Index (PSQI) and a data collection sheet about their demographic and occupational features during an individual face to face interview in central office and firehouses throughout Tehran. Response rate was 88.7%. Results: The mean ± SD global PSQI score was 7.97 ± 3.77. Sleep latency was the component of PSQI with the greatest degree of abnormality. 69.9% of participants were poor sleepers. Interestingly, we found no significant differences between sleep quality of shift workers and non shift workers. Using multiple logistic regression analysis, only having another job, smoking and years of job experience were predictors of poor sleep. Conclusions: In comparison with adult population of Tehran, sleep quality deterioration is notably more common in Tehran firefighters which require health promotion interventions to prevent its serious adverse outcomes.

Background: Addiction to narcotics ‎can cause serious problems and ‎monetary losses. Therapeutic ‎success can be predicted ‎through identifying lapse risk ‎factors.‎ Objective: Determining Job Risk ‎Factor of Lapse.‎ Methods: This was a cross ‎sectional study on 351 addicts ‎visiting five methadone clinics. A ‎Data collection sheet consisting ‎of questions on demographic ‎and job information was filled up ‎through direct interviews. ‎Information relating to lapse in ‎the first month was analyzed.‎ Results: The mean (SD) age of ‎the participants was 40(12) ‎years; of them, 74% were ‎employed, of whom 34% had ‎lapsed. A relationship was ‎noticed between education ‎qualification (secondary school ‎compared with higher and lower ‎education) and lapse (p = .04), ‎and also between type of drug ‎abuse (amphetamine) and lapse ‎‎(p = .001).‎ Conclusion:‎‏ ‏‎ Lapse was more ‎dependent on type of drug abused, ‎and employment had a protective role, ‎with no correlation with the type of ‎job and other job conditions. Non-‎work factors mediated/suppressed the ‎role of occupational conditions.‎

Objective(s): To evaluate the association of parental occupational exposures to six categories of occupational hazards including pesticides, solvents, paint and pigments, organic and non-organic dusts, and metals with the risk of Acute Lymphoblastic Leukemia (ALL) in their offspring.Methods: From 2007-2009 our hospital based case-control study was performed with 200 children diagnosed with ALL and 200 controls consisting of children suffering from endocrine or rheumatologic disorders, who were matched by age and sex. The study was performed at the Children’s Medical Center and Vali-Asr hospital, in Tehran, Iran. The parents were interviewed face to face to gather information on demographic characteristics, child’s medical history and home exposures, and parental occupational histories.Results: We found that paternal exposures to non-organic dusts {OR (95% confidence interval)=2.17 (1.11-4.26); P=0.02} and metals {OR (95% confidence interval)=2.68 (1.38-5.21); P=0.004} were related to an increased risk of ALL in their offspring. No significant relations were found for the other paternal exposure categories neither for the all maternal exposures categories with the risk of ALL in their offspring.Conclusion: Our study provides support to the association between some paternal occupational exposures and ALL risk in their offspring. Further studies are necessary to corroborate the observed associations in this study.

Aim of our study was to investigate the effects of exposure to industrial noise on serum lipid profile among workers who are exposed to noise at work. In a historical cohort study, we recruited 154 and 146 male workers as high and low level noise exposure groups respectively. We defined workers with at least one year exposure to noise level more than 90 dB as high exposure group, and those with exposure to less than 80 dB as low exposure group. Afterwards, in the fasting blood specimens of participants we measured serum Triglyceride (TG), total Cholesterol (TC), high and low density lipoprotein (HDL and LDL). Mean of TG, TC, HDL and LDL for low exposure group were 148, 189, 38 and 103 mg/dl and for high exposure group were 237, 189, 37 and 104 mg/dl respectively. Mean serum TG between two groups was different. Even after adjustment for age, BMI, smoking and work hours per week, serum TG among high exposure group was 89 mg/dl higher than low exposure group and this difference was statistically significant (P=0.00). There was no significant difference between two groups in TC, LDL and HDL levels. This study did not find a statistically significant relationship between exposure to noise and serum TC, LDL and HDL, but TG in two groups was different and this difference was statistically significant.

Background: The present study describes the burden of occupational diseases in Iran based on the results of the Global Burden of Disease study conducted in 2010 (GBD 2010). This study aimed to determine the burden of occupational diseases in Iran based on the results of GBD 2010. It is a cross-sectional study. Methods: Disability-adjusted life years (DALYs) of occupational diseases were calculated based on the prevalence rates obtained through model estimation, as well as GBD 2010 disability weights and mortality rates obtained from different data registry systems of Iran. Causal association criteria application to select risk outcome pairs, estimation of exposure to each risk factor in the population, estimation of etiological effect size, selection of a counterfactual exposure distribution, risk assessment, and identification of burden attributable to each risk factor were the main conducted statistical steps. Results: There was an increasing trend of DALYs (710.08/100,000 people in 1990 and 833.00/100,000 people in 2005) followed by a slight decrease (833.00/100,000 in 2005–784.55/100,000 people in 2010). A total of 50.4% and 36% of total DALYs per 100,000 people were due to the adverse effects of musculoskeletal disorders and work-related injuries, respectively. Conclusions: Musculoskeletal disorders and work-related injuries are the most important adverse consequences of work-related risks that require urgent interventions to be controlled. Male workers (15–25 years and over 60) with the highest DALYs and mortality rates need more training programs, safety regulations, and higher level of protection support. In spite the decreasing trend of occupational disease related DALYs and death rates in Iran in recent years, a long-term effort is required to maintain the currently decreasing trend.

More than one percent of the labor force in each country consists of welders exposed to various damages caused by welding. The number of studies conducted in this field is low, especially in Iran. In this paper, we tried to discover any temporary and reversible obstructive effect of welding fumes on the respiratory systems of welders. In this cross-sectional study, peak expiratory flow rates and respiratory symptoms of 37 welders during work shift were evaluated. Peak expiratory flow rates of welders were recorded in three working days and one non-working day. Peak expiratory flow rates in working days were compared with non-working Peak expiratory flow rates as a control measure. PEF values were higher in every recorded time in non-working days than that of working days. Besides, PEF of the middle shift decreased an hour after end of the shift had increased. Changes in PEF since the start of shift until an hour after the shift had the same pattern in all four days, but in conflict with daily physiological patterns. Fewer people complained respiratory symptoms such as cough and sputum in non-working days. Therefore, exposure to the welding fumes can result in reversible and temporary effect on PEF and this could lead to bronchial irritation and cause respiratory symptoms. Therefore, it is recommended that welders use sufficient respiratory protection and weld in places with air ventilator specialty when welding with CO2 in order to reduce irritant effects of welding fumes on respiratory systems.

Professional firefighting is among the most demanding jobs. Prior studies have showed the notable prevalence of poor sleep quality among professional firefighters that may result in catastrophes. The aim of this study was in field confirmation of zolpidem usage (10 mg/PO/bed time) for short term management of poor sleeps quality among professional firefighters. In a double-blind, randomized, placebo-controlled crossover clinical trial among professional firefighters, 27 poor sleepers were assigned randomly to one of the two groups. Two 14 days experimental periods were separated by a 14-day washout phase. Sleep quality was assessed using the Persian version of Pittsburgh Sleep Quality Index (PSQI). Six of the 27 enrolled voluntaries dropped out. Two rare side effects of zolpidem occurred in the study. A significant improvement of the PSQI score was detected in zolpidem period versus placebo in both groups (7.14 ± 3.02 vs 12.38 ± 2.51, PP=0.89). Zolpidem significantly improved all components of PSQI (Subjective sleep quality, Sleep latency, Sleep duration, Habitual sleep efficiency, Sleep disturbances and Daytime dysfunction) in the current study except the use of sleep medication. Sleep onset latency was the component of PSQI with the greatest degree of abnormality among firefighters in a previous study. Interestingly, sleep latency was the component of PSQI with the most treatment effect of zolpidem in the current study. Zolpidem can be used as a part of treatment regimens in short time management of poor sleep quality among professional firefighters.

Exposure to air pollutants, steel dust or other occupational and environmental hazards as oxidative stress have adverse effects on subway workers' health. Oxidative stress generates an excessive amount of reactive oxygen species (ROS) and Oxygen Free Radicals during their work time in the tunnels. Once DNA is repaired, Urinary 8-hydroxy-deoxyguanosine (8-OHdG) is excreted in the urine. Therefore, urinary level of 8-OHdG can reflect the extent of oxidative DNA damage. The aim of this study was to document the oxidative stress caused by exposure to these hazards by measuring 8-OHdG in workers urine. We collected urine samples of 81 male subway workers after their working shift. The concentration of urinary 8-OHdG was measured by ELISA method. We used linear regression analysis to compare the level of urinary 8-OHdG as a biomarker of oxidative stress between workers in tunnels and other staff. The mean concentration of urinary 8-OHdG for workers in the tunnel was 58.05 (SD=28.83) ng/mg creatinine and for another staff was 54.16 (SD =26.98) ng/mg creatinine. After adjustment for age, smoking, driving and a second job in a linear regression model, the concentration of 8-OHdG for the exposed group was significantly higher than unexposed group (P=0.038). These findings confirm that the concentration of urinary 8-OHdG for workers who work in tunnels was significantly higher than the other staff. Additional investigations should be performed to understand that which ones of occupational exposures are more important to cause oxidative stress.