279 results on '"Ramesh Kumar Sharma"'
Search Results
2. Exploring the efficacy of a novel prebiotic-like growth promoter on broiler chicken production performance
- Author
-
Zulfqarul Haq, Ankur Rastogi, Ramesh Kumar Sharma, Pratiksha Raghuwanshi, Maninder Singh, Azmat Alam Khan, and Syed Mudasir Ahmad
- Subjects
Novel growth promoter ,Antibiotics ,Chicken ,Antimicrobial resistance ,Prebiotic ,Veterinary medicine ,SF600-1100 - Abstract
This study attempts to isolate a candidate growth promoter from the ovine paunch waste and scrutinize its effects on the production performance of broiler chickens as compared to mannan-oligosaccharide (MOS), a prebiotic, and lincomycin, an antibiotic growth promoter (AB). The paunch waste collected from slaughtered sheep was processed to remove particulate matter. The clarified liquid was then added to an excess of ethanol (1:9 ratio), and the resultant precipitate {(novel growth-promoting paunch extract (NGPE)} was collected, dried, and stored. In vitro increase in cell density for probiotic bacteria viz. Lactobacillus rhamnosus and Enterococcus faecalis (Log10 CFU/ml) were significantly higher (P
- Published
- 2024
- Full Text
- View/download PDF
3. Evaluation of native medicinal plants as feed additives in the Sheep ration
- Author
-
DILSHAD KOUR, VIJAY KUMAR SHARMA, RAMESH KUMAR SHARMA, ANAND KUMAR PATHAK, and ANKUR RASTOGI
- Subjects
Feed additives, Herbs, Pimpinella anisum ,Animal culture ,SF1-1100 - Abstract
The present study evaluated nutritional attributes of local medicinal herbs and analysed their effect as feed additives in sheep ration. Proximate and fiber analysis of all herbs- Allium sativa, Cuminum cyminum, Emblica officinalis, Murraya koenigiii, Pimpinella anisum, Sapindus trifoliatus, Terminalia arjuna, Trigonella-foenum graecum, Zingiber officinale, Curcuma longa, Ocimum tenuiflorum and Azadirachta indica and their further screening at different inclusion levels of 3%, 3.5% and 4% of ration to ascertain their effect on in vitro rumen fluid pH, dry matter digestibility and organic matter digestibility of ration was carried out during in vitro phase. Pimpinella anisum @ 3% of ration resulted in significant increase in in vitro dry matter digestibility and in vitro organic matter digestibility of ration. In vivo trial was conducted in which fourteen indigenous, non-descript, adult male sheep (body weight, 27.10±0.10 kg and age, 22-24 months) were randomly allotted into two groups and fed ad lib. wheat straw and concentrate mixture @ 25 g/W0.75 along with Pimpinella anisum @ 3% of ration in treatment group. Comparable OM, CP, EE digestibility was seen in both groups, however, treatment group had significantly higher DM, total carbohydrate, CF, NDF, ADF and HC digestibility. Both groups had positive nitrogen, calcium and phosphorus balance, however, treatment group had significantly increased nitrogen balance. Rumen fermentation parameters were comparable in both groups. Haemoglobin, PCV, serum protein and albumin in treatment group were significantly higher while no significant variation was seen in serum globulin, Albumin:Globulin ratio, total cholesterol, ALT, AST, BUN, creatinine and blood glucose concentration between both groups. It can be inferred from the above data that Pimpinella anisum @ 3% of ration can effectively be used as a feed additive in sheep ration for improving feed intake, nutrient digestibility and utilisation.
- Published
- 2023
- Full Text
- View/download PDF
4. Congenital palatal fistula: Case report and review of literature
- Author
-
Sneha Gulati, Aditya Shivaji Yadav, and Ramesh Kumar Sharma
- Subjects
congenital palatal fistula ,hard palate ,palatal muscles ,palatoplasty ,soft palate ,submucous palate ,Dentistry ,RK1-715 ,Surgery ,RD1-811 - Abstract
Congenital palatal fistula (CPF) is the rarest phenotypic variation of cleft palate, commonly associated with submucous cleft palate (SCP). Isolated palatal fistula without SCP has been reported only rarely. We report here the case of a 4-year-old child, with a 10 mm × 5 mm CPF, presenting with nasal regurgitation and speech abnormalities. The patient had unilateral palatal muscular malposition without classical features of SCP. The repair was performed using turnover flaps and Bardach's two-long flap palatoplasty and intravelar veloplasty. Healing occurred without any complications.
- Published
- 2023
- Full Text
- View/download PDF
5. Comparison of blood loss at the donor site & Acute cardiovascular effects by using adrenaline infiltration and topical adrenaline during skin graft harvest
- Author
-
Chethan L., Harish Kumar, Ramesh Kumar Sharma, and Sandhya Yaddanapudi
- Subjects
blood loss ,heart rate ,blood pressure ,donor site ,topical adrenaline ,adrenaline infiltration ,Medicine - Abstract
Background. Burn surgery is associated with high blood loss to both the donor and recipient site. Although various techniques for reducing intraoperative blood loss have been described, topical adrenaline and adrenaline infiltration have significantly reduced blood loss. The present study compared blood loss to the donor site and acute cardiovascular effects (such as heart rate/ HR and blood pressure/ BP), by using adrenaline infiltration and topical adrenaline while harvesting the skin graft in the same patient, but in a different place. Materials and Methods. It is a prospective study that included 50 patients, all undergoing skin graft harvesting using method 1 and local adrenaline - method 2, in different locations. Blood loss and acute cardiovascular effects were assessed and compared between two methods. Results. Blood loss at the donor site is significantly lower in adrenaline infiltration compared to topical infiltration (4.7±0.6 ml vs 10.4±1.2 ml, p
- Published
- 2022
- Full Text
- View/download PDF
6. The Impact of 'COVID-19' and 'Webinar Pandemic' on Plastic Surgery Practice in Teaching Institutes and Resident Training—A Multicentric Perspective
- Author
-
Satyaswarup Tripathy, Devi Prasad Mohapatra, Ranjit Kumar Sahu, Subair Mohsina, Ramesh Kumar Sharma, Subhendu Khan, Sharda Renu, Chandra Kunwari Singh, Suraj R. Nair, Shijina Koliath, and Imran Pathan
- Subjects
hand trauma ,faciomaxillary injury ,malignancy reconstruction ,aesthetic procedures ,webinar ,conferences ,Surgery ,RD1-811 - Abstract
Introduction The study was carried out to quantify the changes induced by the pandemic in plastic surgery practice and training and to study the impact of the webinars on plastic surgery education from a residents’ perspective. Methods In this multicentric study, the number and type of surgeries, cause of injuries, and their regional variation during the coronavirus disease 2019 (COVID-19) period (February–September 2020) were compared with pre–COVID-19 time. An online survey on the impact of webinars was conducted for plastic surgery trainees across the country. Results There was a significant reduction in total number of surgeries (p = 0.003). The procedures for hand (p = 0.156), faciomaxillary injuries (p = 0.25), and replantations (p = 0.46) were comparable; there was a significant reduction in combined orthopedic-plastic-surgical procedures (p = 0.009) during the pandemic. There was a significant reduction in road accidents (p = 0.007) and suicidal injuries (p = 0.002) and increase in assault (p = 0.03) and domestic accidents (p = 0.01) during the COVID-19 period. A usefulness score of >8 was given for the webinars by 68.7% residents. There was no significant difference in perception of utility when correlated with the academic program at their institutes (p = 0.109); 92% opined webinars should continue in post-COVID times. Conclusion There was a drastic reduction in number of elective and emergency procedures during the COVID-19 time, negatively affecting resident training program. Majority of residents felt that webinars could prove a useful adjunct to training in formal training program in post-COVID-19 scenario.
- Published
- 2022
- Full Text
- View/download PDF
7. An Innovative Skin Simulation Model to Augment Competency-based Training in Facial Plastic Surgery
- Author
-
Satyaswarup Tripathy, Devi Prasad Mohapatra, Friji Meethale Thiruvoth, Ramesh Kumar Sharma, Likhitha Reddy, and Neljo Thomas
- Subjects
residents training ,cbme ,facial plastic surgery ,flaps ,surgical simulation ,Surgery ,RD1-811 - Abstract
Introduction Competency-based medical education (CBME) approach in the medical curriculum has been introduced globally with the goal of providing flexibility, accountability, and learner-centeredness among medical learners. Traditional surgical skill training in most places has relied on “see one, do one, teach one model,” while simulation model-based training has been shown to improve competencies in surgical trainees. We wanted to assess the usefulness of a hydrophilic barrier adhesive foam wound dressing as a novel skin simulation model for learning biomechanics and practice of cutaneous flaps among plastic surgical resident trainees at our institute. Materials and Methods An absorbent, soft polyurethane foam pad located centrally upon a larger polyurethane membrane, coated with a hydrocolloid adhesive, forming an island dressing, was used as a simulation model for this study. It was obtained from the hospital store either after or nearing their expiry dates of clinical use. Plastic surgery residents in different years of training were invited to participate in a simulation workshop, using this novel model, and give their feedback. Results Seventeen residents in different plastic surgery training levels participated in the workshop and gave their feedback on the skin flap simulation model. The simulation model received extremely high (100%) scores on two parameters, namely, utility for flap and suture practice and high scores (88%–94%) for texture, ability to mark, and improving confidence among trainees. Conclusions Adhesive bilayer polyurethane foam can be used as a novel cutaneous skin flap simulation model for understanding the biomechanics of skin flaps and cutaneous flap practice.
- Published
- 2022
- Full Text
- View/download PDF
8. Clinical Outcomes of Surgical Management of Primary Brachial Plexus Tumors
- Author
-
Sunil Gaba, Subair Mohsina, Jerry R. John, Satyaswarup Tripathy, and Ramesh Kumar Sharma
- Subjects
schwannoma ,neurofibroma ,microneurolysis ,paresthesia ,dumbbell tumor ,Surgery ,RD1-811 - Abstract
Introduction This study evaluates the clinical presentation, tumor characteristics, and clinical outcomes of surgically treated benign and malignant brachial plexus tumors (BPTs). Methods A prospective study of patients with BPTs from June 2015 to August 2020 was conducted. All patients underwent surgical resection with microneurolysis and intraoperative electrical stimulation to preserve the functioning nerve fascicles. Results Fourteen patients with 15 BPTs underwent surgical resection. Mean age was 37.8 ± 12.3 years; with male to female ratio 4:10. The clinical presentations were swelling (100%), pain (84.6%), and paresthesia (76.9%). The lesions involved roots (5/15), trunk (5/15), division (1/15), and cords (4/15). Thirteen patients had benign pathology (8 schwannomas, 3 neurofibromas, 2 lipomas) and two had malignant neurofibrosarcoma. Gross total resection was achieved in all cases except a dumbbell tumor. The mean follow-up period was 24 ± 5 months. Postoperatively, all patients reported improvement in pain and paresthesia with no new sensory deficit. All patients had developed initial motor weakness (Grades 2–4); however, full power (Grade 5) was recovered by 3 to 5 months. Conclusion Total resection can be achieved by appropriate microneural dissection and electrophysiologic monitoring and is potentially curative with preserving function.
- Published
- 2021
- Full Text
- View/download PDF
9. Triangular flap technique for unilateral cleft lip deformity
- Author
-
Ramesh Kumar Sharma
- Subjects
cleft lip ,complete and incomplete ,repair ,triangular flap technique ,Dentistry ,RK1-715 ,Surgery ,RD1-811 - Abstract
The triangular flap lip repair is one of the two main techniques used for the correction of a cleft lip deformity worldwide. Many surgeons in Indian subcontinent and Europe use the triangle flap technique as their first choice. This CME article describes the details of the triangular flap technique as modified by Dr. C P Sawhney. The rationale of the technique, lip markings, planning of incisions, and the detailed operative steps are described. The merits and demerits of this versatile technique are also discussed.
- Published
- 2021
- Full Text
- View/download PDF
10. Distraction Lengthening of First Metacarpal in Traumatic Thumb Amputations
- Author
-
Abid Saleem, Ramesh Kumar Sharma, and Parmod Kumar
- Subjects
thumb amputation ,distraction ,callotasis ,phalangization ,pollicization ,Surgery ,RD1-811 - Abstract
Introduction Based on the level of the thumb loss, phalangization, toe-to-thumb transfer, pollicization, and distraction callotasis of the first metacarpal are the various options available for reconstruction. The aims of the study were to observe the length gained in the distraction process, duration of treatment required, functional recovery in the form of pinch strength, sensations, and patient satisfaction. Patients and Methods It was a prospective study of 10 patients of thumb amputation, conducted from January 2014 to July 2015. The patients’ age, mode of injury, level of amputation, and advantages and disadvantages of distraction callotasis were evaluated. Results The most common etiology of thumb loss was domestic accidents while working with a chaff cutter. The total duration of treatment was 124 (93–165) days and the mean gain in length was 25 (20–28) mm. The pinch strength increased from a mean of 0.91 to 2.06 kg, i.e., a 44.17% improvement from preoperative pinch strength. All of our patients retained their sensations of the reconstructed thumb post distraction. Conclusions Among many options for thumb reconstruction, distraction callotasis is a simple and safer option in the selective group of patients who are not keen on toe-to-thumb transfer which provide a significant improvement. The longer duration of treatment is the disadvantage associated with the need for proper counselling beforehand.
- Published
- 2019
- Full Text
- View/download PDF
11. Columellar strut graft in unilateral cleft nasal deformity: Anthropometry and clinical outcomes
- Author
-
Kumar Prasad Preetha Rani, Atul Parashar, and Ramesh Kumar Sharma
- Subjects
columellar strut graft ,tip projection ,unilateral cleft nasal deformity ,Dentistry ,RK1-715 ,Surgery ,RD1-811 - Abstract
Introduction: The cleft nasal deformity is a three-dimensional asymmetry involving all layers of the nose. Columellar strut graft is an important method to provide support to the skeletal framework in an attempt to retain structural support and balance. Aims: The purpose of our study is to describe the surgical outcomes following the use of columellar strut graft when it is used in secondary cleft rhinoplasty. The study was designed to identify the changes in tip projection (Tip Proj), tip rotation (Tip Rot), and other anthropometric measurements postoperatively. Materials and Methods: A prospective study was conducted among patients presenting with secondary cleft nasal deformity and operated utilizing a columellar strut graft. The parameters considered were columellar height (CH), columellar width, Tip Proj, Tip Rot, nasofrontal angle, nasofacial angle, and nasolabial angle. All the measurements were analyzed statistically. Results: During the study, results could be evaluated for 25 patients. The Tip Proj increased in 84% of patients, and the magnitude of difference between pre- and post-operative follow-up at 9 months was found to be statistically significant (P = 0.009). The CH increased in 20 patients (80%). The Tip Rot increased in 20 patients (80%). The postoperative changes were consistently maintained at different follow-up intervals. Conclusions: Columellar strut is necessary in improving the Tip Proj, correcting the tilted tripod and lower lateral cartilage deformities. It also functions as a central scaffold on which the tip structures can be unified.
- Published
- 2019
- Full Text
- View/download PDF
12. Changing trends in plastic surgery training
- Author
-
Ramesh Kumar Sharma
- Subjects
course duration ,evaluation ,plastic surgery ,reconstructive and aesthetic content ,training ,Surgery ,RD1-811 - Abstract
Background: The currently available training models are being put to scrutiny in India today, both by the residents and the teachers. Plastic surgery specialty was created primarily for reconstructive purposes but the society always perceived it from a cosmetic angle, particularly in the post second world war era. As a result, there is a need to redefine the goals of plastic surgery training in the present times so that the plastic surgeon is ‘future ready’ to meet the needs of society and the market forces. Materials and Methods: The author has reviewed the currently available literature on plastic surgery training from India and the western countries. An attempt has been made to study opinions from the teachers and the trainees. The modules currently available in India and abroad have been analyzed and a suggestion has been made for drafting training programs that would meet the demands of the society as well as prepare the resident both for the aesthetic and reconstructive practice. Conclusions: The plastic surgery training needs to be more vibrant and in tune with the changing times. While maintaining its core nature, the current predominantly reconstructive modules need to incorporate the aesthetic content. The evaluation should be both knowledge and competence based. The teachers need to be educated in the various teaching methods that are more applicable to grown up residents. There is a need to find ways to attract talented people in the academic plastic surgery.
- Published
- 2014
- Full Text
- View/download PDF
13. A hybrid technique of trapezius muscle transfer for a flail shoulder in late brachial plexus injuries
- Author
-
Akhil Garg, K. S. Ajai, Satyaswarup Tripathy, Nirmal Raj Gopinathan, and Ramesh Kumar Sharma
- Subjects
Surgery ,RD1-811 - Published
- 2018
- Full Text
- View/download PDF
14. Unfavourable results in craniofacial surgery
- Author
-
Ramesh Kumar Sharma
- Subjects
Complications ,craniofacial surgery ,Post-graduate Institute of Medical Education and Research Chandigarh ,unfavourable results ,Surgery ,RD1-811 - Abstract
Craniofacial surgery is one of the newer subspecialties of plastic surgery and owes its birth to the pioneering work of Paul Tessier in the late sixties. Since then this challenging specialty work has been taken up by many centres around the word including India. Initial reports in late eighties and early nineties showed morbidity and mortality ranging from 1.6% to 4.3%. However over past few decades, with improved instrumentations, safer anaesthesia and cumulative experience of surgeons the morbidity and mortality has been brought down to as low as 0.1% in many centres in USA. In our centre at Post-graduate Institute, Chandigarh, the mortality rate is about 0.8% (4 out of 480 cases). The learning curve in this surgery is rather steep but with experience and a well-coordinated team work, results in this complex subspecialty can be improved. The infection is a major cause for worry but can be easily prevented by sound surgical principles and placing a vascularised tissue barrier between the extradural space and the nasopharynx/sinus mucosa.
- Published
- 2013
- Full Text
- View/download PDF
15. Craniosynostosis
- Author
-
Ramesh Kumar Sharma
- Subjects
Abnormal skull shapes ,cosmetic and functional issues ,cranioplasty ,fronto-orbital advancement ,premature suture fusion ,Surgery ,RD1-811 - Abstract
Craniosynostosis is a premature pathologic fusion of one or more cranial vault sutures that leads to abnormal shape of the skull. The fused sutures lead to restricted growth in some areas and compensatory bossing in other areas. The head may assume different shapes depending upon the site and timing of the abnormally fused suture. The exact cause of this suture pathology is still unknown, but the local dura, cranial base and the fibroblast growth factors seem to influence this. The diagnosis rests on clinical examination and confirmation is generally on the computed tomography scan. The need for surgery is both for cosmetic and functional reasons. Many cases may be associated with raised intracranial pressure with its attendant deleterious effects on vision and brain. The aim of treatment is to increase the cranial volume and reshape the skull. The surgery can be safely undertaken around 9-12 months in most of the cases. The conventional management is through an open surgical approach; although, some centres have claimed impressive results with limited endoscopic techniques in selected cases. The review article deals with the aetiopathogenesis, clinical presentations and management of the common varieties of craniosynostoses seen in the Indian scenario.
- Published
- 2013
- Full Text
- View/download PDF
16. Protocol of an observational study to evaluate diabetic nephropathy through detection of microalbuminuria in Indian patients
- Author
-
Gokulnath, Manisha Sahay, Sanjay Kalra, Vijay Vishwanathan, Abdul Hamid Zargar, Pradeep G Talwalkar, Subhash Kumar Wangnoo, Debasish Maji, G Vijay Kumar, Ramesh Kumar Sharma, Deodatta Chafekar, Brij Mohan, Ganapathi Bantwal, Anil Bansali, and Jasmeet Singh Sahni
- Subjects
Diabetic nephropathy ,dipstick test ,health policy ,India ,microalbuminuria ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 ,Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Aim: To assess the prevalence of persistent microalbuminuria (MAU), its clinical correlates by dip stick method, its predictive value for potential kidney disease and the utility of this test as objective cue for health care seeking behavior in adult Indian patients with type 2 diabetes mellitus. Materials and Methods: Approximately 400,000 patients shall be enrolled in this multicentric, cross sectional study. Patients meeting eligibility criteria shall be screened for MAU through urine dipstick test using random daytime single spot urine specimen. Result shall be expressed either positive or negative based on the presence or absence of albumin in the urine and will be correlated with the corresponding random blood glucose. Height, weight, waist circumference and blood pressure shall be assessed. There will be three visits with a minimum interval of 28 days between two visits, to be completed within 180 days, and at least two of three urine tests measured in this period must show elevated albumin levels to diagnose MAU. Conclusion: Detection of MAU through the dipstick method is postulated to be a rapid, reliable test for early detection of diabetic nephropathy, which, in turn will help the physician to plan treatment strategy. Further, it will help to identify the disease burden on the individual and society, and may serve as an objective cue for improved health care seeking behavior, as well as a catalyst for health policy change.
- Published
- 2013
- Full Text
- View/download PDF
17. Unfavourable outcomes in maxillofacial injuries: How to avoid and manage
- Author
-
Atul Parashar and Ramesh Kumar Sharma
- Subjects
Craniofacial skeleton ,faciomaxillary injuries ,fracture ,post-traumatic deformity ,Surgery ,RD1-811 - Abstract
Faciomaxillary injuries remain one of the common injuries managed by plastic surgeons. The goal of treatment in these injuries is the three-dimensional restoration of the disturbed anatomy so as to achieve pre-injury form and function. In this article, the authors review the anatomic, diagnostic and management considerations to optimise results and minimise the late post-traumatic deformities. Most of the adverse outcomes are usually a result of poorly addressed underlying structural injury during the primary management. An accurate physical examination combined with detailed computed tomographic scanning of the craniofacial skeleton is required to generate an appropriate treatment plan. This organised approach has proven effective in restoring the injured structures to pre-injury status. Multiple clinical cases are used to illustrate the different fracture patterns along with various surgical techniques to achieve an acceptable outcome. Early diagnosis and timely management of complications in these complex injuries is also discussed.
- Published
- 2013
- Full Text
- View/download PDF
18. A novel method to insert drain atraumatically after liposuction in gynaecomastia
- Author
-
Sunil Gaba, K. S. Ajai, Ramesh Kumar Sharma, and L. Chetan
- Subjects
Surgery ,RD1-811 - Published
- 2018
- Full Text
- View/download PDF
19. Role of stem cells in the management of chronic wounds
- Author
-
Ramesh Kumar Sharma and Jerry R. John
- Subjects
adult stem cells ,chronic wound ,stem cells ,Surgery ,RD1-811 - Abstract
Chronic wounds continue to be a major challenge for the medical profession, and plastic surgeons are frequently called in to help in the management of such wounds. Apart from the obvious morbidity to the patient, these problem wounds can be a major drain on the already scarce hospital resources. Sometimes, these chronic wounds can be more taxing than the underlying disease itself. Although many newer methods are available to handle such situations, the role of stem cells in the management of such wounds is an exciting area that needs to be explored further. A review of literature has been done regarding the role of stem cells in the management of chronic wounds. The abnormal pathology in such wounds is discussed and the possible role of stem cells for optimal healing in such cases would be detailed.
- Published
- 2012
- Full Text
- View/download PDF
20. Assessment of the abdominal wall function after pedicled TRAM flap surgery for breast reconstruction: Use of modified mesh repair for the donor defect
- Author
-
Chacko Cyriac, Ramesh Kumar Sharma, and Gurpreet Singh
- Subjects
abdominal wall function ,patient questionnaire ,pedicled tram flap breast reconstruction ,straight and lateral curl ups ,Surgery ,RD1-811 - Abstract
Background: The pedicled TRAM flap has been a workhorse of autologous breast reconstruction for decades. However, there has been a rising concern about the abdominal wall donor site morbidity with the use of conventional TRAM flap. This has generally been cited as one of the main reasons for resorting to “abdominal wall friendly” techniques. This study has been undertaken to assess the abdominal wall function in patients with pedicled TRAM flap breast reconstruction. The entire width of the muscle and the overlying wide disk of anterior rectus sheath were harvested with the TRAM flap in all our patients and the anterior rectus sheath defect was repaired by a Proline mesh. Materials and Methods: Abdominal wall function was studied in 21 patients who underwent simultaneous primary unipedicled TRAM flap reconstruction after mastectomy for cancer. In all the patients, the abdominal wall defect was repaired using wide sheet of Proline mesh both as inlay and onlay. The assessment tools included straight and rotational curl ups and a subjective questionnaire. The abdominal wall was also examined for any asymmetry, bulge, or hernia. The minimal follow-up was 6 months postoperative. The objective results were compared with normal unoperated volunteers. Results and Conclusions: The harvesting the TRAM flap certainly results in changes to the anterior abdominal wall that can express themselves to a variable degree. A relatively high incidence of asymptomatic asymmetry of the abdomen was seen. There was total absence of hernia in our series even after a mean follow-up period of 15.5 months. A few patients were only able to partially initiate the sit up movement and suffered an important loss of strength. In most patients, synergists took over the functional movement but as the load increased, flexion and rotation performances decreased. The lack of correlation between exercise tests and the results of the questionnaire suggests that this statistically significant impairment was functionally not important. The patients encountered little or no difficulty in theis day-to-day activities. Our modification of use of a wide mesh as inlay and onlay repair minimizes the donor site morbidity. This also avoids maneuvers meant for primary closure of the rectus sheath defects, which can result in distortion of umbilicus. Therefore, in conclusion, the unipedicled TRAM flap should be regarded as a valuable option in breast reconstruction provided careful repair of the abdominal wall defect is undertaken using Proline mesh.
- Published
- 2010
- Full Text
- View/download PDF
21. The pedicled thoraco-umbilical flap: A versatile technique for upper limb coverage
- Author
-
Sharad Mishra and Ramesh Kumar Sharma
- Subjects
upper limb soft tissue defects ,thoraco-umbilical flap ,periumbilical perforators ,deep inferior epigastric artery ,Surgery ,RD1-811 - Abstract
Injuries to upper limb has been on the increase and is invariably associated with significant soft tissue loss requiring a flap cover. Local tissue may not be available for cover in a majority of situations, necessitating import of tissue from a distant source. We have utilized the thoraco-umbilical flap taken from the trunk for this purpose. This flap is based on the perforators of the deep inferior epigastric artery that are maximally centred on the periumbilical region. This flap was used in 83 patients. The patients were observed for at least 3 weeks and any flap or donor site complications were recorded. The patients were again followed up at 3 months interval and the donor site scar was assessed. The flaps survived in 81 patients; there was marginal flap necrosis in five patients and partial flap necrosis in two patients. None of these patients required any additional procedure for coverage. The flap is technically easy to plan, almost effortless to drape around upper limb defects, with no significant donor site morbidity and also the post operative immobilization was fairly comfortable. The thoraco-umbilical flap thus is a very useful technique for coverage of the upper limb and is recommended as a first line flap for this purpose.
- Published
- 2009
- Full Text
- View/download PDF
22. Submental tracheal intubation in oromaxillofacial surgery
- Author
-
Ramesh Kumar Sharma, Puneet Tuli, Chacko Cyriac, Atul Parashar, and Surinder Makkar
- Subjects
avoiding tracheostomy ,oromaxillofacial surgery ,intubation ,Surgery ,RD1-811 - Abstract
Background: oromaxillofacial surgical procedures present a unique set of problems both for the surgeon and for the anesthesist. achieving dental occlusion is one of the fundamental aims of most oromaxillofacial procedures. oral intubation precludes this surgical prerequisite of checking dental occlusion. having the tube in the field of surgery is often disturbing for the surgeon too, especially in the patient for whom skull base surgery is planned. nasotracheal intubation is usually contraindicated in the presence of nasal bone fractures seen either in isolation or as a component of le fort fractures. we utilized submental endotracheal intubation in such situations and the experience has been very satisfying.materials and methods: the technique has been used in 20 patients with maxillofacial injuries and those requiring le fort i approach with or without maxillary swing for skull base tumors. initial oral intubation is done with a flexo-metallic tube. a small 1.5 cm incision is given in the submental region and a blunt tunnel is created in the floor of the mouth staying close to the lingual surface of mandible and a small opening is made in the mucosa. the tracheal end of tube is stabilized with magil′s forceps, and the proximal end is brought out through submental incision by using a blunt hemostat taking care not to injure the pilot balloon. at the end of procedure extubation is done through submental location only.results: the technique of submental intubation was used in a series of twenty patients from january 2005 to date. there were fifteen male patients and five female patients with a mean age of twenty seven years (range 10 to 52). seven patients had le fort i osteotomy as part of the approach for skull base surgery. twelve patients had midfacial fractures at the le fort ii level, of which 8 patients in addition had naso-ethomoidal fractures and 10 patients an associated fracture mandible. twelve patients were extubated in the theatre. eight patients had delayed extubation in the post-operative ward between 1 and 3 days postoperatively.conclusion: in conclusion, the submental intubation technique has proved to be a simple solution for many a difficult problem one would encounter during oromaxillofacial surgical procedures. it provides a safe and reliable route for the endotracheal tube during intubation while staying clear of the surgical field and permitting the checking of the dental occlusion, all without causing any significant morbidity for the patient. its usefulness both in the emergency setting and for elective procedures has been proved. the simplicity of the technique with no specialized equipment or technical expertise required makes it especially advantageous. this technique therefore, when used in appropriate cases, allows both the surgeon and the anesthetist deliver a better quality of patient care.
- Published
- 2008
- Full Text
- View/download PDF
23. Perforator plus flap: Evolution of the concept and its place in plastic surgeons repertoire
- Author
-
Ramesh Kumar Sharma
- Subjects
Surgery ,RD1-811 - Published
- 2010
- Full Text
- View/download PDF
24. An alternative receptacle for fat harvest: The infant mucous sucker
- Author
-
Satyaswarup Tripathy, Saurabh Rawat, Jerry R. John, and Ramesh Kumar Sharma
- Subjects
Surgery ,RD1-811 - Published
- 2016
- Full Text
- View/download PDF
25. The Scope of Craniofacial Surgery
- Author
-
Ian T. Jackson and Ramesh Kumar Sharma
- Subjects
Surgery ,RD1-811 - Published
- 1994
- Full Text
- View/download PDF
26. Special considerations in paediatric burn patients
- Author
-
Ramesh Kumar Sharma and Atul Parashar
- Subjects
burn injuries ,paediatric ,special considerations ,Surgery ,RD1-811 - Abstract
Burn injuries are a major cause of morbidity and mortality in children. In India, the figure constitutes about one-fourth of the total burn accidents. The management of paediatric burns can be a major challenge for the treating unit. One has to keep in mind that “children are not merely small adults”; there are certain features in this age group that warrant special attention. The peculiarities in the physiology of fluid and electrolyte handling, the uniqueness of the energy requirement and the differences in the various body proportions in children dictate that the paediatric burn management should be taken with a different perspective than for adults. This review article would deal with the special situations that need to be addressed while treating this special class of thermal injuries. We must ensure that not only the children survive the initial injury, but also the morbidity and complications are minimized. If special care is taken during the initial management of paediatric burn injuries, these children can be effectively integrated into the society as very useful and productive members.
- Published
- 2010
- Full Text
- View/download PDF
27. Problems of middle ear and hearing in cleft children
- Author
-
Ramesh Kumar Sharma and Vipul Nanda
- Subjects
cleft lip and palate ,hearing loss ,middle ear infection ,Surgery ,RD1-811 - Abstract
The hearing loss in a cleft patient is a well known complication, but generally gets ignored. These children continue to have recurrent otitis media with effusion that affects the hearing abilities. Unfortunatley the middle ear function may not improve with palatoplasty. Cleft palate teams need to follow up all such children beginning at birth and going into adulthood, decades after a ‘successful’ palate repair. These patients should have careful otological and audiological surveillance with appropriate interventions whenever required. The review article discusses the current status of hearing management in patients with cleft palate.
- Published
- 2009
- Full Text
- View/download PDF
28. Use of HDPE implants in facial skeletal augmentation: Should we rush for it?
- Author
-
Ramesh Kumar Sharma
- Subjects
Surgery ,RD1-811 - Published
- 2010
- Full Text
- View/download PDF
29. Adversity: A great teacher
- Author
-
Ramesh Kumar Sharma
- Subjects
Surgery ,RD1-811 - Published
- 2013
- Full Text
- View/download PDF
30. Effect of single dose intravenous tranexamic acid on blood loss in tangential excision of burn wounds — A double blind randomised controlled trial
- Author
-
Ramesh Kumar Sharma, Parmod Kumar, Mohsina Subair, and K S Ajai
- Subjects
Blood Loss, Surgical ,Critical Care and Intensive Care Medicine ,Single Center ,Placebo group ,law.invention ,Double blind ,Hemoglobins ,Double-Blind Method ,Randomized controlled trial ,Blood loss ,law ,medicine ,Humans ,Prospective Studies ,business.industry ,General Medicine ,Antifibrinolytic Agents ,Tranexamic Acid ,Anesthesia ,Emergency Medicine ,Surgery ,Hemoglobin ,Burns ,business ,Body mass index ,Tranexamic acid ,medicine.drug - Abstract
This study was carried out to evaluate role of intravenous tranexamic acid (TXA) in reducing blood loss during tangential excision of burns.This was a single center, prospective double-blinded parallel arm superiority randomized placebo-controlled trial. Patients (15-55 years) with deep dermal thermal burns30% undergoing tangential excision were randomly assigned (1:1) to TXA and placebo groups. Patients in TXA and placebo groups received injection TXA 15 mg/kg and 10 ml saline respectively, 10 min preoperatively. Primary outcome was volume of blood loss per square centimeter area of burn excised. Secondary outcomes were total volume of blood loss, postoperative hemoglobin, intraoperative fluid requirement, blood transfusion, graft take and length of hospitalization (LOH).Thirty patients were included. Both groups were comparable in terms of Body Mass Index (BMI) preoperative hemoglobin, area of burn excised, duration of surgery and the intraoperative temperature. The average blood loss per square centimeter burn area excised was found to be significantly lower in TXA when compared to placebo group (mean difference: 0.28 ± 0.025 ml/cmTXA reduced blood loss per unit burn area of tangential excision in30%TBSA burn, however, we found no significant effect on postoperative Hb and transfusion.
- Published
- 2022
- Full Text
- View/download PDF
31. Division of Fasciocutaneous Pedicled Flaps—Is It Time to Change Practice?
- Author
-
Subair, Mohsina, Ramesh Kumar, Sharma, Jerry R, John, Satya Swarup, Tripathy, and Harbans, Singh
- Subjects
Postoperative Complications ,Child, Preschool ,Quality of Life ,Wound Infection ,Humans ,Surgery ,Prospective Studies ,Plastic Surgery Procedures ,Surgical Flaps - Abstract
The study was carried out to evaluate the safety of early division of the pedicled flaps and to identify the optimum day of division.This prospective, parallel arm, open-label, noninferiority, randomized controlled trial was carried out from January 2019 to July 2020. All patients (age, ≥5 years) undergoing reconstructive procedures using pedicled flaps were randomized in 1:1 ratio to receive either early division or conventional division protocol. In the early-division group, the flap perfusion, if satisfactory on day 8 by clinical and thermographic methods, a clamp was applied on the pedicle. The clamp was gradually tightened to produce controlled delay, and perfusion assessment was repeated after complete tightening. If satisfactory, the flaps were divided. Primary endpoints were flap at 24 hours after division, day of division, and day of complete inset of the flap. Secondary end points included perfusion of the flap on day 8, morbidity parameters (wound infection/suture dehiscence, need for secondary surgery and donor site morbidity), quality of life, and function scores.Thirty-five patients were included in each group. The 2 groups were similar in terms of various demographic, clinicopathological variables, defect and flap characteristics. The flap survival rate was similar (P = 0.31) between the early (34/35) and standard (35/35) division groups. The early-division group had a significantly early mean day of flap division (mean difference of 12.74 days; P0.00001) and complete flap inset (mean difference of 12.09 days; P0.00001). All flaps had satisfactory perfusion on day 8. The wound infection rate was 1.33 times significantly higher in the conventional group (P = 0.033). There was a higher incidence of donor site morbidity (9% vs 0%) in the conventional group when compared with the early division group. The quality of life and function scores at 3 weeks (mean difference 2.37; P0.001) and 6 weeks (mean difference 3.76; P0.001) and adjacent joint stiffness were significantly higher in the early division group when compared with conventional group.The pedicled flaps can be divided significantly early at an average duration of 10 to 11 days after flap inset with increased patient satisfaction rate and with a reduced postoperative morbidity. The authors have included a diversity of pedicled flaps used in different anatomic locations. By using stratified block randomization, we could ensure that the distribution was similar between the 2 groups, thus minimizing the heterogeneity in the analysis. This could also potentially indicate the usefulness of the controlled delay technique, irrespective of the anatomic location and type of the flap.
- Published
- 2022
- Full Text
- View/download PDF
32. Occupational Stress- Addressing Woes of the Nurses in a Burn Unit
- Author
-
Kajal Gupta, Monaliza Monaliza, Karobi Das, and Ramesh Kumar Sharma
- Subjects
Nursing ,Feeling ,Lived experience ,media_common.quotation_subject ,Stressor ,Learned helplessness ,General Medicine ,Occupational stress ,Psychology ,Work environment ,media_common ,Unit (housing) - Abstract
Occupational stress can leave the nurses drained while caring for patients in the burn unit. This existential-phenomenological study aimed to explore burn unit nurses' lived experiences of occupational stressors and organizational support. Twenty-two nurses working in the burn unit were interviewed. Data were analyzed utilizing Colaizzi's 7-step method. Three themes were generated: stressful work environment; feelings of helplessness; need for organizational support. Nurses reported that organizational support should be available for dealing with the work-related stressors in the burn unit.
- Published
- 2021
- Full Text
- View/download PDF
33. CAN MEDIA LITERACY HELP FIGHT THE INFODEMIC? A STUDY OF YOUTH
- Author
-
Ms. Priyanka Sachdeva, Dr. Durgesh Tripathi, Dr. Ramesh Kumar Sharma, and Ms. Surbhi Tandon
- Subjects
Infodemic, Media Literacy, democratic country, social media, COVID-19 - Abstract
COVID-19 a worldwide catastrophe, and while humankind is grappling to find a solution. The pandemic has adversely affected the citizens globally both physically and psychologically, and the torrent of information is acting as a double whammy. The past research delineates that media literacy's paucity is missing in Youth, which involves critical thinking skills, analyzing and evaluating media messages. Media Literacy is emerging as a critical challenge amongst the citizens. The interdisciplinary nature of media literacy sets a foundation for understanding and participating in the public good's ongoing dialogue. In COVID-19 times, where there are restrictions on many activities and services, the research portrays that the social media usage among people has amplified to an extraordinary rate. In isolation, people are more dependent on online information. The plethora of information available online is fake and misleading, termed as ‘Infodemic’. This kind of information is risky and poses harmful effects. The most vulnerable to such a risk are Youth, as they are heedless of the adverse effects and deprive the skills of identifying the reliability and credibility of the news story. The present study with exploratory cum descriptive design attempts to determine whether the Youth are media literate or not and how they make distinctions among fake and reliable news. It also finds out that how information sharing and consumption has changed due to the pandemic. The survey method finds that people are more dependent on social media networks for news and other information. The Youth do encounter fake news and feels that it creates confusion among people. The Media Literacy skills were tested with the help of a five-point Likert scale. The findings reveal that the Youth lacks media literacy skills, and it should be taught in schools and colleges to churn out informed citizenry. The study concludes that social media platforms with the power of engaging and informing the citizens when used mindfully and with a developed knowledge structure can make wonders in a democratic country like India
- Published
- 2022
- Full Text
- View/download PDF
34. Early Wound Cover of Gunshot Injury to the Leg with Free Composite Anterolateral Thigh Flap: a Case Report
- Author
-
Raman Sharma, Ramesh Kumar Sharma, Raghavendra Kaladagi, and Jerry R. John
- Subjects
medicine.medical_specialty ,Debridement ,business.industry ,medicine.medical_treatment ,GUNSHOT INJURY ,Surgical debridement ,Soft tissue ,Anterolateral thigh ,Neurovascular bundle ,Tissue transfer ,Surgery ,body regions ,medicine ,business ,Through and through - Abstract
The damage caused by gunshot injuries (GSI) is often unpredictable. In the civilian population, majority of the extremity injuries are due to handguns. GSI have a high risk of neurovascular injury, compartment syndrome, wound contamination, comminuted fractures with devitalized bony fragments, and extensive soft tissue damage. Neurovascular damage is the primary cause of mortality and morbidity in GSI involving extremities. These injuries require emergent surgical debridement and irrigation. Often, serial debridements are required before reconstruction. The lower leg has extremely less redundant soft tissue support. Thus, local options are very limited and distant tissue transfer is required for the reconstruction. Free composite anterolateral thigh flap is a versatile armamentarium for the reconstruction of through and through soft tissue defect of the distal leg. We report a case of GSI to the distal third of the leg which was treated successfully using debridement and free composite anterolateral thigh (ALT) flap transfer.
- Published
- 2021
- Full Text
- View/download PDF
35. Ian T. Jackson: Colossus of Craniofacial Surgery
- Author
-
Ramesh Kumar Sharma
- Subjects
medicine.medical_specialty ,Colossus computer ,business.industry ,General surgery ,lcsh:Surgery ,MEDLINE ,lcsh:RD1-811 ,Icon of the Issue ,law.invention ,law ,medicine ,Surgery ,business ,Craniofacial surgery - Published
- 2021
- Full Text
- View/download PDF
36. Reverse Sural Artery Flap for Dorsum of Foot Reconstruction
- Author
-
Suraj Nair, Ramesh Kumar Sharma, Jerry R. John, Mohsina Subair, Sunil Gaba, and Gowtham Kampalli
- Subjects
Peroneal Artery ,medicine.medical_specialty ,Reconstructive Surgeon ,integumentary system ,Vascular disease ,business.industry ,medicine.medical_treatment ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Vascularity ,medicine.artery ,medicine ,Skin grafting ,Ankle ,medicine.symptom ,business ,Sural arteries ,Foot (unit) - Abstract
Loss of skin over the dorsum of foot is a common clinical entity. Infection, trauma, and vascular disease represent the most common etiological factors. Salvage of foot in these cases has a bearing upon the quality of life of the patient. The reconstruction process is often complex and varied as per exigencies. Reverse sural artery flap is an easy and reliable option for reconstruction of dorsum of foot defect. Reverse sural artery draws its vascularity from the communication of the peroneal artery and the median sural artery. The flow of the flap is from the distal to the proximal and represents an elegant option for dorsum of foot. We have described the peninsular variant of the reverse sural artery. The coverage of the defects of the dorsum of foot in trauma can be performed either immediately if the wound conditions are favorable or we may have to delay the procedure of definitive cover by a few days till the wound conditions improve by use of vacuum-assisted closure (VAC) application. Split thickness graft, reverse sural artery flap, and free flaps provide safe and viable options for dorsum of foot defects. Reverse sural artery is reliable option in the armamentarium of the reconstructive surgeon. Gaba S, Sharma RK, John JR, et al. Reverse Sural Artery Flap for Dorsum of Foot Reconstruction. J Foot Ankle Surg (Asia Pacific) 2021;8(1):28–32.
- Published
- 2021
- Full Text
- View/download PDF
37. Relativistic longitudinal self-compression of ultra-intense Gaussian laser pulses in magnetized plasma
- Author
-
Pradeep Kothiyal, Ramesh Kumar Sharma, Gunjan Purohit, and Priyanka Rawat
- Subjects
Physics ,Paraxial approximation ,Pulse duration ,Plasma ,Condensed Matter Physics ,Laser ,Atomic and Molecular Physics, and Optics ,Intensity (physics) ,Magnetic field ,Computational physics ,Pulse (physics) ,law.invention ,symbols.namesake ,law ,symbols ,Electrical and Electronic Engineering ,Nonlinear Schrödinger equation - Abstract
This article presents a preliminary study of the longitudinal self-compression of ultra-intense Gaussian laser pulse in a magnetized plasma, when relativistic nonlinearity is active. This study has been carried out in 1D geometry under a nonlinear Schrodinger equation and higher-order paraxial (nonparaxial) approximation. The nonlinear differential equations for self-compression and self-focusing have been derived and solved by the analytical and numerical methods. The dielectric function and the eikonal have been expanded up to the fourth power of r (radial distance). The effect of initial parameters, namely incident laser intensity, magnetic field, and initial pulse duration on the compression of a relativistic Gaussian laser pulse have been explored. The results are compared with paraxial-ray approximation. It is found that the compression of pulse and pulse intensity of the compressed pulse is significantly enhanced in the nonparaxial region. It is observed that the compression of the high-intensity laser pulse depends on the intensity of laser beam (a0), magnetic field (ωc), and initial pulse width (τ0). The preliminary results show that the pulse is more compressed by increasing the values of a0, ωc, and τ0.
- Published
- 2020
- Full Text
- View/download PDF
38. Effect of fertigation levels and spacing on growth and yield of cucumber (Cucumis sativus L.) cv. KPCH-1 grown under polyhouse
- Author
-
Ramesh Kumar Sharma, Suman Kumari, Ajay Bhardwaj, Randhir Kumar, and Paramveer Singh
- Subjects
Fertigation ,biology ,Vegetative reproduction ,Phosphorus ,Randomized block design ,chemistry.chemical_element ,engineering.material ,Interaction ,biology.organism_classification ,Crop ,Horticulture ,chemistry ,engineering ,Fertilizer ,Cucumis ,Mathematics - Abstract
An experiment was conducted to study the effect of different spacing and fertigation levels on growth and yield of cucumber (Cucumis sativus L.) cv. KPCH-1 under naturally ventilated polyhouse. The experiment was laid out following Factorial Randomized Block Design (FRBD) with three replications.The experiment wascomprised of total nine treatment combinations of two factors, three levels of spacing viz. 60 cm × 35 cm (S1), 60 cm × 35 cm (S2) and 60 cm × 55 cm (S3) with three levels of fertigation viz. 80% RDF (F1), 100% RDF (F2) and 120% RDF (F3). Among the treatment combinations, S3F2treatment (60 cm ×55 cm with 100% RDF) showed the best interaction effect for vine length at 30 DAT (69.47 cm), at 60 DAT (229.40cm), at final harvest (339.73 cm),crop duration (103.93 days)number of fruits per vine (37.67), fruit length (17.13 cm), fruit girth (11.57 cm),average fruit weight (122.33 g), fruit yield per vine (4.20 kg), days to first flower appearance (28.13 days), intermodal length (8.90 cm), nodal position of first flower (2.73) and days to first picking of fruits (35.93 days). The maximum vegetative growth and yield of the cucumber were found in S3F2 treatment. The maximum available nitrogen, available phosphorus and available potassium were found in S3F3 (60 cm ×55 cm with120 % RDF as compared to initial fertilizer in polyhouse. The maximum benefit-cost ratio was found in the treatment S3F2 (2.90) followed by S3F1 (2.67). Based on these findings, it is recommended that spacing of 60 cm × 55 cm and application of fertilizer with 100% RDF under naturally ventilated polyhouse is economical and found suitable for vegetative growth and yield of the cucumber.
- Published
- 2020
- Full Text
- View/download PDF
39. Comparison of Magnetic Resonance Imaging and Ultrasonography in Diagnosing and Grading Carpal Tunnel Syndrome: A Prospective Study
- Author
-
Barun Bagga, Niranjan Khandelwal, Manish Modi, Ramesh Kumar Sharma, Anindita Sinha, and Chirag Kamal Ahuja
- Subjects
Adult ,Male ,Wrist Joint ,Sensitivity and Specificity ,Severity of Illness Index ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Vascularity ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Prospective Studies ,Prospective cohort study ,Carpal tunnel syndrome ,Ultrasonography ,Pisiform bone ,medicine.diagnostic_test ,Receiver operating characteristic ,business.industry ,Reproducibility of Results ,Echogenicity ,Magnetic resonance imaging ,Middle Aged ,medicine.disease ,Carpal Tunnel Syndrome ,Magnetic Resonance Imaging ,Median nerve ,Median Nerve ,030220 oncology & carcinogenesis ,Female ,medicine.symptom ,Nuclear medicine ,business - Abstract
Objective To use anatomic measurements on magnetic resonance imaging (MRI) and ultrasonography (USG) in diagnosing and grading carpal tunnel syndrome (CTS) using nerve conduction studies (NCS) as the gold standard. Material and methods In this prospective study, 26 patients with CTS (45 wrists; 22 female and 4 male patients; mean ± SD age of 49.42 + 14.47 years) and 19 age and sex matched healthy volunteers (32 wrists; 15 female and 4 male volunteers, mean ± SD age of 42.52 + 10.85 years) underwent MRI and USG. Cross-sectional area (CA) of median nerve was measured using free hand ROI at four levels: hamate hook (H0), pisiform bone (PI0), 1 cm proximal (PI1) and 2 cm proximal to PI0 (PI2). Relative median nerve signal intensity (MNSI) was calculated as ratio of median nerve signal intensity with hypothenar muscle signal intensity. Flexor retinacular bowing was calculated at hamate hook level. Echogenicity and Power Doppler vascularity of median nerve were assessed on USG. Independent t-test, chi square test and receiver operating characteristic curve analysis were used as appropriate. Results On USG, CA measured at PI0 (95% confidence interval of 0.872-0.987) and retinacular bowing (0.816-0.912), while, on MRI, CA at PI1 (0.874-0.997) were most useful in diagnosing CTS based on the ROC and Zombie plot analysis. Area under curves for CA measurements on USG and MRI were not significantly different. CA at PI1 on MRI (0.752-0.965) was significantly different between minimal to moderate CTS and severe to extreme CTS groups (on NCS). Conclusion CA of median nerve is the most useful parameter to diagnose and grade CTS and USG and MRI are comparable for measurements. Increased retinacular bowing on USG and hypoechogenicity of median nerve increase the diagnostic confidence while MRI helps in picking up important associated conditions.
- Published
- 2020
- Full Text
- View/download PDF
40. Advancing Sowing Time and Conservation Tillage - The Climate-Resilient Approach to Enhance the Productivity and Profitability of Wheat
- Author
-
Rajender Singh Chhokar, Ramesh Kumar Sharma, Neeraj Kumar, Ram Kumar Singh, and Gyanendra Pratap Singh
- Subjects
Plant Science ,Agronomy and Crop Science - Abstract
Field experiments consisting of two sowing time (early and timely), two tillage options (conventional tillage and conservation tillage) and ten genotypes were conducted with the aim to maximize the wheat productivity and profitability. The early sowing (second fortnight of October) produced 16.0% higher grain yield compared to timely sowing (mid-November) in northern Indian Plains. However, no significant yield differences were observed between conventional tillage (CT) and conservation tillage (CST) practices. Among genotypes, the better yielders were PBW 723, BISA 927 and HD 2967. The interaction of sowing time and genotype had a significant (p 0.05) effect on wheat yield. However, the interaction of genotype and tillage did not produce any significant response on wheat yield. The experiments conducted at farmer's fields also demonstrated similar performance of wheat under CT and CST systems but CST offered the savings of more than Rs. 3500 (US $ 47) along with 125 kg ha
- Published
- 2022
41. Improved Agronomic Practices for Enhancing the Resource Use Efficiency and Productivity of Wheat and Barley
- Author
-
Rajender Singh Chhokar, Neeraj Kumar, Ramesh Kumar Sharma, Subhash Chander Gill, Ajit Singh Kharub, Anil Kumar Khippal, and Subhash Chander Tripathi
- Published
- 2022
- Full Text
- View/download PDF
42. The Role of Glycoalkaloids, Lipids, and Proteins in Tissue Inflammation
- Author
-
Pasqualina Laganà, Ramesh Kumar Sharma, and Maria Anna Coniglio
- Subjects
Chemistry ,Tissue inflammation ,Cell biology - Published
- 2021
- Full Text
- View/download PDF
43. Fruits and Vegetables, Though Rich in Antioxidants, Might Lead to Cytotoxicity
- Author
-
Maria Anna Coniglio, Pasqualina Laganà, and Ramesh Kumar Sharma
- Subjects
Lead (geology) ,Chemistry ,Fruits and vegetables ,Food science ,Cytotoxicity - Published
- 2021
- Full Text
- View/download PDF
44. Determination of Inflammatory Molecules in Fruits and Vegetables
- Author
-
Pasqualina Laganà, Ramesh Kumar Sharma, and Maria Anna Coniglio
- Subjects
Antioxidant ,food.ingredient ,Vitamin C ,medicine.medical_treatment ,Food additive ,food and beverages ,Ripening ,Riboflavin ,Biology ,Pesticide ,food ,Fruits and vegetables ,medicine ,Inflammatory molecules ,Food science - Abstract
Different vegetable foods could unpredictably cause similar inflammatory reactions when speaking of human diets. Several unrefined carbohydrates and fresh oils, and also several pulses can be the cause of mild surplus oxidation. These situations appear in contrast with common knowledge speaking of foods and beverages with antioxidant or anti-inflammatory properties. For these and other reasons, vegan/vegetarian dietary lifestyles appear to be successful at present. However, intensive farming practices concerning fruits and vegetables worldwide have progressively caused a decline in the amount of protein, phosphorus, iron, riboflavin, and vitamin C in modern food products belonging to this ambit. As a result, organophosphorus pesticides are now detectable in fruits, vegetables, and wheat. Because of their inflammatory effects on the human body, and also considering their persistency in the environment, these molecules are of extreme interest. This worry is also present when speaking of chemical agents used for artificial ripening, with concern to fruits. The category of powdered juices can also contain different food additives with possible inflammatory, cytotoxic, and /or genotoxic effects. Several inflammatory molecules of natural origin exist: fructose, purines, and alkaloids. This chapter concerns the analytical detection of these chemical classes.
- Published
- 2021
- Full Text
- View/download PDF
45. Natural Inflammatory Molecules in Fruits and Vegetables: Alkaloids, Uric Acid, and Fructose
- Author
-
Pasqualina Laganà, Ramesh Kumar Sharma, and Maria Anna Coniglio
- Subjects
Purine ,Sucrose ,Starch ,food and beverages ,Fructose ,Photosynthesis ,medicine.disease ,chemistry.chemical_compound ,chemistry ,Biochemistry ,medicine ,Uric acid ,Autotroph ,Hyperuricemia - Abstract
Out of several energy-rich organic compounds formed via photosynthesis in autotrophic organisms like plants, a few of them might prove inflammatory or cytotoxic molecules for humans if consumed regularly. Using previously stored chemical energy, chloroplasts convert atmospheric carbon dioxide mainly into glucose and a little fructose which—in the next step—are combined to yield sucrose, starch, cellulose, etc. Nitrogenous compounds, including proteins, are produced in the consequent step in plants. Purines are nitrogenous molecules that, on regular consumption, can create pathogenesis of gout and hyperuricemia in humans. The cytotoxic effects of foods rich in fructose and purines are well known. On the other hand, the plant defence system produces certain compounds which protect the plants against microorganisms and insects and, on regular consumption, might create inflammation in the human body. The set of plant defensive inflammatory molecules include a variety of alkaloids. In this chapter, an attempt is made to present an overview of natural inflammatory molecules—fructose, purines, and alkaloids—contained in fruits and vegetables.
- Published
- 2021
- Full Text
- View/download PDF
46. Selection of Fruits and Vegetables with Public Health Viewpoint: Discussion
- Author
-
Pasqualina Laganà, Ramesh Kumar Sharma, and Maria Anna Coniglio
- Subjects
chemistry.chemical_classification ,Chemistry ,business.industry ,digestive, oral, and skin physiology ,food and beverages ,Ready to eat ,Sweetness ,Maillard reaction ,symbols.namesake ,Fruits and vegetables ,symbols ,Food processing ,Food science ,Palatability ,business ,Polyunsaturated fatty acid ,High energy food - Abstract
Proteins and lipids are molecules that might be considered as soft targets for oxidative attack, whose modification in the body can increase the risk of inflammation due to mutagenesis. Effects of food processing additives with oxidant attitude are known. Consequently, oxidation during food processing may be a problem, especially when speaking of high-energy foods derived from cereals, with notable amounts of oxidation-sensible lipids and protein chains. The public health perspective with relation to some natural molecules which might lead to excessive oxidation reactions in the human body is extremely important. Consequently, some discussion should be dedicated to unsaturated fatty acids and some of the known polypeptides in cereal-based high-energy foods. Processed high-energy bars and other snacks derived from cereals are really ‘energetic’ if compared with whole cereal grains, and the palatability is directly proportional to the amount of sugars (sweetness) and fats/oils. However, other problems could occur when speaking of high-energy foods. Ultraprocessed foods are completely dissimilar from original foods, and these products contain a notable amount of oxidation-sensible molecules: lipids and proteins. Consequently, processing and non-processing factors could have some important public safety consequences. The aim of this chapter is to give some perspective to this ambit.
- Published
- 2021
- Full Text
- View/download PDF
47. Ultrasonographic measurement of tongue thickness to predict upper airway obstruction after palatoplasty: A preliminary cohort study
- Author
-
Preethy J Mathew, Sandhya Yaddanapudi, Vighnesh Ashok, Neerja Bhardwaj, Ramesh Kumar Sharma, and Ratnakumar Banoth
- Subjects
medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Airway obstruction ,medicine.disease ,Surgery ,Airway Obstruction ,Cleft Palate ,Cohort Studies ,Anesthesiology and Pain Medicine ,Palatoplasty ,medicine.anatomical_structure ,Tongue ,medicine ,Humans ,business ,Cohort study - Published
- 2021
48. No Traces of SARS-CoV-2 In Wounds of COVID-19 Positive Patients: A Pilot Study
- Author
-
Kapil Goyal, Poonam Chauhan, Vikas Suri, Shyam Charan Meena, Ankur Bhatnagar, Ramesh Kumar Sharma, Mini P Singh, Gowtham Kampalli, and Sunil Gaba
- Subjects
2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,rrt-pcr ,wound swab ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,lcsh:Surgery ,030230 surgery ,Virus ,law.invention ,03 medical and health sciences ,sars-cov-2 virus ,0302 clinical medicine ,law ,Medicine ,Special Topic ,Polymerase chain reaction ,integumentary system ,business.industry ,030208 emergency & critical care medicine ,lcsh:RD1-811 ,Virology ,Reverse transcriptase ,covid-19 ,Nasal Swab ,Surgery ,business - Abstract
Background This study was performed to investigate the presence of SARS-CoV-2 virus in wounds of COVID-19 positive patients. Methods This is a single-center observational study. COVID-19 patients with wounds (traumatic/infective/surgical) were included in this study. Preoperative, intraoperative, or postoperative specimens were collected and analyzed with real-time reverse transcriptase polymerase chain reaction (rRT-PCR) to know the presence of the virus. Results A total of eight patients were included in this study. Eleven samples were collected (seven wound swabs, two peritoneal fluids, and two tissue specimens) and analyzed. None of the samples from the wound tested positive for the virus while they were tested positive for nasal swab taken simultaneously or within 3 days prior. Conclusion The wounds of COVID-19 patients are considered negative and can be managed with routine wound precautions.
- Published
- 2020
- Full Text
- View/download PDF
49. Rotation Flaps in Series
- Author
-
Ramesh Kumar Sharma and Raman Sharma
- Subjects
Adult ,Male ,Rotation flap ,Scalp ,Rotation ,business.industry ,One stage ,030206 dentistry ,General Medicine ,Anatomy ,Plastic Surgery Procedures ,Surgical Flaps ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Otorhinolaryngology ,medicine ,Humans ,Surgery ,Full thickness ,Occipital Lobe ,030223 otorhinolaryngology ,business - Abstract
A 42-year-old man presented with 2 full thickness defects in left parieto-temporal and right temporo-occipital regions with normal intervening scalp tissue. These 2 adjacent but discontinuous defects were covered in one stage with an innovative rotation flap design that provided 1 flap each for these 2 defects. This innovative flap design permitted one stage reconstruction with primary closure of the donor sites.
- Published
- 2020
- Full Text
- View/download PDF
50. Donor Site Changes in Bone Thickness, Volume, and Density Following Split Cranial Bone Graft Harvest
- Author
-
Ramesh Kumar Sharma, Sandeep B, Jerry R. John, and Niranjan Khandelwal
- Subjects
Adult ,Male ,medicine.medical_specialty ,Bone thickness ,Adolescent ,Bone density increased ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,X ray computed ,Humans ,Medicine ,Prospective Studies ,030223 otorhinolaryngology ,Prospective cohort study ,Bone Transplantation ,business.industry ,Skull ,Autogenous bone graft ,030206 dentistry ,General Medicine ,Surgery ,Otorhinolaryngology ,Cranial bone ,Female ,Tomography, X-Ray Computed ,business ,Volume (compression) - Abstract
The calvarium can provide large amount of good quality corticocancellous autogenous bone graft. Although many studies have highlighted the advantages of the split cranial bone graft, there is no published work available in the literature about the fate of donor site of the split cranial bone graft. The present study was undertaken to assess the donor site as regards to the thickness, volume, and the density of the residual bone over a period of 12 months in the postoperative period. A total of 30 patients in the age group of 15 to 43 years were studied from January 2015 to January 2016. Postoperative computer tomography scans were taken at 2 weeks, 6 months, and 1 year postoperative to measure the bone thickness, volume, and density at the donor site of the split cranial bone graft harvest. The bone thickness at the donor site showed progressive increase in the thickness over the period of study and the average increase in thickness was about 12.4% at the end of 1 year. The average increase in volume at the donor site was of 2.65% after 12 months. Similarly, the average bone density increased by 3.7% at the end of 1 year. This prospective study conclusively proves that the residual bone at the donor site of the split cranial bone graft harvest site continues to grow in thickness and density over a period of 1 year.
- Published
- 2019
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.