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15 results on '"Ramaswamy, Anjali"'

3. Digital elixir for healthcare: market intelligence and policy implications

Author

Gowda, Naveen R., Vikas, H., Satpathy, Sidhartha, Ramaswamy, Anjali, Prabhu, Meghana, Kumar, Atul, Kini, Ananth, Singh, Angel Rajan, Sharma, D. K., Desai, Devashish, Sharma, J. B., Gowda, Praveen R., Rajkumar, Gopinath, Bharath, Huded, Chandrashekhar, Sowmya, K. P., Divya, T. K., Vakharia, Khyati, Viswanath, Somanath, John, Dhayal C., and Gudipati, Neeraj

Published
2023
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8. Cytokinopathy with aberrant cytotoxic lymphocytes and profibrotic myeloid response in SARS-CoV-2 mRNA vaccine–associated myocarditis

Author

Barmada, Anis, primary, Klein, Jon, additional, Ramaswamy, Anjali, additional, Brodsky, Nina N., additional, Jaycox, Jillian R., additional, Sheikha, Hassan, additional, Jones, Kate M., additional, Habet, Victoria, additional, Campbell, Melissa, additional, Sumida, Tomokazu S., additional, Kontorovich, Amy, additional, Bogunovic, Dusan, additional, Oliveira, Carlos R., additional, Steele, Jeremy, additional, Hall, E. Kevin, additional, Pena-Hernandez, Mario, additional, Monteiro, Valter, additional, Lucas, Carolina, additional, Ring, Aaron M., additional, Omer, Saad B., additional, Iwasaki, Akiko, additional, Yildirim, Inci, additional, and Lucas, Carrie L., additional

Published
2023
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9. Data from YAP Is Essential for Treg-Mediated Suppression of Antitumor Immunity

Author

Ni, Xuhao, primary, Tao, Jinhui, primary, Barbi, Joseph, primary, Chen, Qian, primary, Park, Benjamin V., primary, Li, Zhiguang, primary, Zhang, Nailing, primary, Lebid, Andriana, primary, Ramaswamy, Anjali, primary, Wei, Ping, primary, Zheng, Ying, primary, Zhang, Xuehong, primary, Wu, Xingmei, primary, Vignali, Paolo, primary, Yang, Cui-Ping, primary, Li, Huabin, primary, Pardoll, Drew, primary, Lu, Ling, primary, Pan, Duojia, primary, and Pan, Fan, primary

Published
2023
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10. Figure S1 to S13 from YAP Is Essential for Treg-Mediated Suppression of Antitumor Immunity

Author

Ni, Xuhao, primary, Tao, Jinhui, primary, Barbi, Joseph, primary, Chen, Qian, primary, Park, Benjamin V., primary, Li, Zhiguang, primary, Zhang, Nailing, primary, Lebid, Andriana, primary, Ramaswamy, Anjali, primary, Wei, Ping, primary, Zheng, Ying, primary, Zhang, Xuehong, primary, Wu, Xingmei, primary, Vignali, Paolo, primary, Yang, Cui-Ping, primary, Li, Huabin, primary, Pardoll, Drew, primary, Lu, Ling, primary, Pan, Duojia, primary, and Pan, Fan, primary

Published
2023
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12. Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children

Author

Ramaswamy, Anjali, primary, Brodsky, Nina N., additional, Sumida, Tomokazu S., additional, Comi, Michela, additional, Asashima, Hiromitsu, additional, Hoehn, Kenneth B., additional, Li, Ningshan, additional, Liu, Yunqing, additional, Shah, Aagam, additional, Ravindra, Neal G., additional, Bishai, Jason, additional, Khan, Alamzeb, additional, Lau, William, additional, Sellers, Brian, additional, Bansal, Neha, additional, Guerrerio, Pamela, additional, Unterman, Avraham, additional, Habet, Victoria, additional, Rice, Andrew J., additional, Catanzaro, Jason, additional, Chandnani, Harsha, additional, Lopez, Merrick, additional, Kaminski, Naftali, additional, Dela Cruz, Charles S., additional, Tsang, John S., additional, Wang, Zuoheng, additional, Yan, Xiting, additional, Kleinstein, Steven H., additional, van Dijk, David, additional, Pierce, Richard W., additional, Hafler, David A., additional, and Lucas, Carrie L., additional

Published
2021
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13. Post-infectious inflammatory disease in MIS-C features elevated cytotoxicity signatures and autoreactivity that correlates with severity

Author

Ramaswamy, Anjali, primary, Brodsky, Nina N., additional, Sumida, Tomokazu S., additional, Comi, Michela, additional, Asashima, Hiromitsu, additional, Hoehn, Kenneth B., additional, Li, Ningshan, additional, Liu, Yunqing, additional, Shah, Aagam, additional, Ravindra, Neal G., additional, Bishai, Jason, additional, Khan, Alamzeb, additional, Lau, William, additional, Sellers, Brian, additional, Bansal, Neha, additional, Guerrerio, Pamela, additional, Unterman, Avraham, additional, Habet, Victoria, additional, Rice, Andrew J., additional, Catanzaro, Jason, additional, Chandnani, Harsha, additional, Lopez, Merrick, additional, Kaminski, Naftali, additional, Dela Cruz, Charles S., additional, Tsang, John S., additional, Wang, Zuoheng, additional, Yan, Xiting, additional, Kleinstein, Steven H., additional, van Dijk, David, additional, Pierce, Richard W., additional, Hafler, David A., additional, and Lucas, Carrie L., additional

Published
2020
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14. YAP Is Essential for Treg-Mediated Suppression of Antitumor Immunity

Author

Ni, Xuhao, primary, Tao, Jinhui, additional, Barbi, Joseph, additional, Chen, Qian, additional, Park, Benjamin V., additional, Li, Zhiguang, additional, Zhang, Nailing, additional, Lebid, Andriana, additional, Ramaswamy, Anjali, additional, Wei, Ping, additional, Zheng, Ying, additional, Zhang, Xuehong, additional, Wu, Xingmei, additional, Vignali, Paolo, additional, Yang, Cui-Ping, additional, Li, Huabin, additional, Pardoll, Drew, additional, Lu, Ling, additional, Pan, Duojia, additional, and Pan, Fan, additional

Published
2018
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15. Post-infectious inflammatory disease in MIS-C features elevated cytotoxicity signatures and autoreactivity that correlates with severity.

Author

Ramaswamy A, Brodsky NN, Sumida TS, Comi M, Asashima H, Hoehn KB, Li N, Liu Y, Shah A, Ravindra NG, Bishai J, Khan A, Lau W, Sellers B, Bansal N, Guerrerio P, Unterman A, Habet V, Rice AJ, Catanzaro J, Chandnani H, Lopez M, Kaminski N, Dela Cruz CS, Tsang JS, Wang Z, Yan X, Kleinstein SH, van Dijk D, Pierce RW, Hafler DA, and Lucas CL

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a life-threatening post-infectious complication occurring unpredictably weeks after mild or asymptomatic SARS-CoV2 infection in otherwise healthy children. Here, we define immune abnormalities in MIS-C compared to adult COVID-19 and pediatric/adult healthy controls using single-cell RNA sequencing, antigen receptor repertoire analysis, unbiased serum proteomics, and in vitro assays. Despite no evidence of active infection, we uncover elevated S100A-family alarmins in myeloid cells and marked enrichment of serum proteins that map to myeloid cells and pathways including cytokines, complement/coagulation, and fluid shear stress in MIS-C patients. Moreover, NK and CD8 T cell cytotoxicity genes are elevated, and plasmablasts harboring IgG1 and IgG3 are expanded. Consistently, we detect elevated binding of serum IgG from severe MIS-C patients to activated human cardiac microvascular endothelial cells in culture. Thus, we define immunopathology features of MIS-C with implications for predicting and managing this SARS-CoV2-induced critical illness in children.

Published
2021
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