1. Oral Zinc as an Adjunct in the Treatment of Enteric Fever: A Randomised Double-blinded Controlled Trial
- Author
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Ramakrishnan Arumanandal Pachamuthu, Sowmya Sampath, Ramya Rajamanickam, Aparna Jayaraman, and Shobhana Sivathanu
- Subjects
early defervescence ,placebo ,toxaemia ,tropical disease ,Medicine - Abstract
Introduction: Enteric fever is an important tropical disease which takes an average of five days for defervescence even with effective antibiotic therapy. Zinc has been successfully used as an adjuvant in diarrhoeal disease. If addition of oral zinc can lead to reduction in time to defervescence, it will be a useful adjuvant in the therapy of enteric fever. Aim: To determine the effect of oral zinc supplementation, along with standard antibiotic therapy, for early defervescence among children with enteric fever. Materials and Methods: This double-blinded, randomised controlled trial was conducted at the Department of Paediatrics, ESICMC and PGIMSR, Chennai, Tamil Nadu, India from November 2014 to August 2016. A total of 58 children aged
- Published
- 2023
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