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Teratoma is frequently found in mixed germ cell testicular tumors in up to 80% of cases, but as a pure component it is reported in only 2–6% of cases. Metastatic disease may be seen in 29–76% of these cases in the adult population. We present the case of a 32 year old male patient diagnosed with a pure testicular teratoma in clinical stage I and a right renal cyst Bosniak IIF, as part of treatment he received chemotherapy, during which, radiological changes were observed at the level of renal cyst suggesting metastatic tumor.

Testicular cancer accounts for 1% of male neoplasms, the most common histology is bilateral presentation is reported in 1–2% of cases, and germ cell tumor histology represents 90–95% of cases. Especifically, choriocarcinoma as a pure component represents 0.3–1% of these neoplasms and as a mixed component, 8%. We present a 26-year-old male patient with bilateral Wunderlich syndrome secondary to renal metastases from testicular choriocarcinoma. Keywords: Germ cell tumor, Choriocarcinoma, Testicular cancer, Wunderlich syndrome, Choriocarcinoma syndrome

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Background: Invasive breast cancer is the most common carcinoma in women, 23% of all cancers in the world. It is classified according to its histological pattern and expression of immunohistochemical markers; 75% are ductal type. The incidence of metastasis is 10 to 80% of the cases according to their immunophenotype, the main sites of metastasis are bone, visceral and brain. Clinical case: A 64 years old lady with a history of radical left mastectomy due to unspecified breast cancer in 2000, received chemotherapy, radiation therapy and tamoxifen. After her discharge from hospital, the patient remained unattended. In 2014 she started with dysphagia, in 2016 was documented esophageal stricture by panendoscopy, three endoscopic dilations were performed, in the last one she presented incidental perforation. An esophagectomy was performed; the pathological study reported metastasis of ductal carcinoma of the breast. Conclusions: Ductal carcinoma of the breast rarely metastasizes to the digestive tract but, its probability must have this and insist on monitoring of patients after their cancer treatment. [ABSTRACT FROM AUTHOR]

Background: Mature teratomas belong to the group of germ line ovarian tumors; they generally have benign behavior. Malignant transformation occurs in 0.2% to 1% of tumors. The objective is to show the results of peritonectomy with HIPEC in the treatment of a mature teratoma with malignant differentiation with signet ring cells., Clinical Case: 43-year-old woman diagnosed with mature malignant teratoma with signet ring cells. It was performed optimal primary cytoreduction surgery, total hysterectomy, bilateral salpingo-oophorectomy, peritonectomy, appendectomy, cholecystectomy and splenectomy adding intraoperative hyperthermic chemotherapy (HIPEC)., Conclusions: Malignant transformation of a mature teratoma of the ovary is a rare event, but not exceptional. HIPEC was used after optimal cytoreduction, with good results, since the patient is in a disease-free period of 36 months. It is necessary to report cases in order to compare different types of treatment to improve oncological results., (© 2023 Revista Médica del Instituto Mexicano del Seguro Social.)