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Mucormycosisis an opportunistic infection which is caused by fungus of the order Mucorales most common one is Rhizopus oryzae. These infections are more common in patients which are suffering from diabetes mellitus, malignancy, burn, severe trauma, malnutrition, renal failure, prolong neutropenia, immunosuppressed, long term steroid therapy or immunosuppressive therapy, hematopoietic stem cell transplant and solid organ transplant recipients. Patients with serious illness are 10 times more prone to develop bacterial or fungal secondary infection than secondary viral infection.Commonest form of presentation of Rhino-orbito-cerebral mucormycosis dental pain4, dental loosening, orbital pain, facial numbness, conjunctival suffusion, diminution of vision to complete ophthalmoplegia, blindness, cavernous sinus thrombosis, multiple cranial nerve palsies, edema of eyelids orbital inflammation blepharoptosis, proptosis, acute ocular motility changes, headache and acute vision loss.Management of mucormycosiscomprises of medical and surgical management.Various surgical management are explained.

Fungal rhinosinusitis (FRS) once considered a rare disease. This global rise in the burden of fungal disease is a consequence of an increment in the population with weakened immune systems. Increased life expectancy with rise in conditions like diabetes mellitus, medical advancements with invasive interventions, use of steroid, wider uses of broad-spectrum antibiotics, immunosuppressive treatments for transplantation and autoimmune diseases, increased incidence of immune deficiency disease. Fungal infections of the paranasal sinuses are in fact a spectrum of diseases rather than one distinct entity. As such, there has been much published on the classification of fungal rhinosinusitis (FRS).Early classifications of FRS used the causative organism as the descriptor, i.e., aspergillosis, mucormycosis, etc. Rapid diagnosis and prompt treatment may save at least some of these patients. When fever with neutropenia and sinonasal symptoms are seen in patients with impaired immune function maintaining a high index of suspicion is essential, and the appropriate diagnostic work up should involve imaging studies and nasal endoscopy with a possible biopsy so as to initiate treatment in a timely manner.Clinical and histopathologic features of fungal rhinosinusitis are specific to each form, and criteria for diagnosis have been developed. This review of fungal sinus diseases summarizes invasive and noninvasive fungal rhinosinusitis forms but concentrates on AFS because of its high prevalence and the fundamental role the allergist-immunologist plays in its diagnosis and treatment.

Now a days, it is an arduous task for the customers to buy an electric car due to day-to-day increased market competition, advanced technology, diversified product etc. To conquer this problem, we have used MCDM techniques to distinguish and select a best car among all the alternatives. In this study, we have taken eight different electric vehicles of different brands and eight different criteria for optimization. The main criteria’s considered for the analysis are identified by reading literature reviews and interviews with professionals from the Indian automotive industry and consumers are as follow- cost, driving range, acceleration, battery charging time and top speed. AHP methodology is used to define weights for different criteria used in study. Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) and Multi-Objective Optimization based on Ratio Analysis (MOORA) techniques have been used for analysis and the results are compared. Byd E6 is considered to have better performance in both the methods. The results obtained from the method used will be beneficial for customers to distinguish between different electric cars in the current industry.

Wine is not just about taste; it represents your class & overall personality. But tasting the same wine for a long time gets boring; sometimes, everyone needs something new, and for that, we usually get advice from friends. But it is not for sure that their taste will match yours and hence you might not like the wine they like. To resolve this issue, we propose the Greedy Clustering Wine Recommender System (GCWRS). This adaptive wine recommendation system uses principal component analysis (PCA) and K-Means clustering algorithms and a novel ranking algorithm using a greedy technique to recommend wines. Along with that, it also uses the elbow method, which helps find out the ideal number of clusters. Together with the clustering algorithm, the recommendation system is tailored in such a way to help all types of users (the first time tasters or regular wine drinkers) as well as the needs of the users (try something new or enhance their current preferences). The clustering model is trained on the wine dataset (with 6497 entries and 12 attributes) combined with the personal preferences of the user, results in an effective personalized recommendation system. The performance of the model is compared with other standard algorithms like K-means clustering, Agglomerative clustering, DBSCAN, Birch clustering algorithm, using performance evaluation functions like the Silhouette coefficient, Calinski-Harabasz Index, and Davies-Bouldin index. Results indicate that our Greedy Clustering Wine Recommender System (GCWRS) provides a better result than other standard algorithms with Silhouette coefficient=0.28, Calinski-Harabasz Index=2207.84, and Davies-Bouldin index=1.36.

In the past few decades, 1,3-diaryltriazenes had been synthesized and investigated their biological and pharmacological profiles. 1,3-diaryltriazene compounds shows many activities like- anticancer, antioxidant, antimicrobial and anti-diabetic activities. The present study is focused on synthesis of novel series of 1,3-diaryltriazene derivatives from diazonium salt of sulfacetamide sodium and substituted aniline via continuous stirring at 0℃ temp. for 3 hrs. A different color of compounds is obtained and the five novel compounds are confirmed by spectral analysis of NMR, MASS spectroscopy and FTIR. Antioxidant activity of the newly synthesized compound have been investigated by many radical scavenging assays. Compound SSR1 (4-[3-(4-methylphenyl)-triaz-1-en-1-yl]-N-sulfanilyl acetamide sodium) and SSR5 (4-[3-(2-methylphenyl)-triaz-1-en-1-yl]-N-sulfanilyl acetamide sodium) have highest antioxidant potency presented (IC50 value are 241.70 and 256.37 µg/mL respectively for DPPH method. In NO(nitric oxide) radical scavenging assay, compound SSR1(4-[3-(4-methylphenyl)-triaz-1-en-1-yl]-N- sulfanilyl acetamide sodium) and SSR5(4-[3-(2-methylphenyl)-triaz-1-en-1-yl]-N- sulfanilyl acetamide sodium) have highest antioxidant value 75.80 % and 73.80 % respectively and reducing power antioxidant assay of the five compounds (SSR1-SSR5) were evaluated, compound SSR5 (4-[3-(2-methylphenyl)-triaz-1-en-1-yl]-N-sulfanilyl acetamide sodium) have highest antioxidant value.

The procedure of standardising herbal preparations is a key aspect of obtaining the product's quality and efficacy, and it is the rate-limiting stage in Ayurvedic formulations. The data about the concentrations employed in the formulation are provided in detail by the procedure. In this study, standardization of herbal drugs- Foeniculum vulgare was investigated. The formulary of ayurvedic drugs in India was followed in the production. For the standardisation of commercial and in-house ayurvedic medicinal products, the organoleptic qualities, physical properties, and physiological features were utilised. The drug property was evaluated and compared to the reference standards for control and quality assurance in pharmaceutical laboratories using precise and accurate metrics

Aim and objectives:to compare both the ways of xation in randomly selected cases in distal third tibia fractures to known the best way of xation technique & implant. Material and methods: In our study we have selected 40 patients with fractures of the distal third tibia, who attended the department of orthopaedics treated by open reduction and internal xation with using Medial/Lateral distal locking compression plates, in Mahatma Gandhi Medical College & Hospital, Jaipur during the year January 2019 to June 2020. The duration of follow-up to evaluate result was six months. We divided the distal leg bone fractures into two groups. Group 1: Include the distal third tibial fractures which are simple or comminuted treated as open reduction & internal xation with lateral locking compression plate. Group 2: Includes the distal third tibial fractures which are simple or comminuted, treated as open reduction & internal xation with medial locking compression plate. Results: There was no signicant difference in duration of surgeries and suture removal.In there were 3 cases of nonunion 1 case in lateral plating group and 2 cases in medial plating group. Group 1 were show 20% excellent, 45% good, 30% fair & 5% poor result. Group 2 were show 15 % excellent, 30% good, 45% fair &10% poor result according to Tenny & Wiss criteria. Conclusion: Lateral plating was much better in as a procedure and outcome wise.

The capability of the self-attention mechanism to model the long-range dependencies has catapulted its deployment in vision models. Unlike convolution operators, self-attention offers infinite receptive field and enables compute-efficient modeling of global dependencies. However, the existing state-of-the-art attention mechanisms incur high compute and/or parameter overheads, and hence unfit for compact convolutional neural networks (CNNs). In this work, we propose a simple yet effective "Ultra-Lightweight Subspace Attention Mechanism" (ULSAM), which infers different attention maps for each feature map subspace. We argue that leaning separate attention maps for each feature subspace enables multi-scale and multi-frequency feature representation, which is more desirable for fine-grained image classification. Our method of subspace attention is orthogonal and complementary to the existing state-of-the-arts attention mechanisms used in vision models. ULSAM is end-to-end trainable and can be deployed as a plug-and-play module in the pre-existing compact CNNs. Notably, our work is the first attempt that uses a subspace attention mechanism to increase the efficiency of compact CNNs. To show the efficacy of ULSAM, we perform experiments with MobileNet-V1 and MobileNet-V2 as backbone architectures on ImageNet-1K and three fine-grained image classification datasets. We achieve $\approx$13% and $\approx$25% reduction in both the FLOPs and parameter counts of MobileNet-V2 with a 0.27% and more than 1% improvement in top-1 accuracy on the ImageNet-1K and fine-grained image classification datasets (respectively). Code and trained models are available at https://github.com/Nandan91/ULSAM., Accepted as a conference paper in 2020 IEEE Winter Conference on Applications of Computer Vision (WACV)

Thermodynamic properties of glycine and its dipeptide diglycine in aqueous solution of 1-pentyl-3-methylimidazolium chloride, [C5mim][Cl] have been investigated by volumetric and ultrasonic properties at T = (288.15–308.15 K). The apparent molar volumes at infinite dilution, Vϕ0 and the apparent molar isentropic compression at infinite dilution Kϕ , S0, have been calculated from density and speed of sound data. Furthermore, apparent molar expansivity, Eϕ0, Hepler's constant values, ∂ E ϕ 0 ∂ T P and hydration numbers, nH have been evaluated to support the conclusions obtained from the volumetric and acoustic studies. These parameters are helpful to study the structure nurturing, solvation behavior and various interactions present in the ternary solutions of (amino acid/dipeptide + [C5mim][Cl] + water).