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Pulmonary Tuberculosis (PTB) is a significant cause of morbidity, especially in patients with underlying health conditions. The present case highlights the complex management in a patient with intricate medical history, marked by tuberculosis, multiple Intercostal Chest Drain (ICD) procedures, and pyopneumothorax with long-standing diabetes mellitus and a history of smoking, adding to the uniqueness of the case. The authors present a case of a 67-year-old male, admitted for a right Pneumonectomy (PE) due to a complex combination of pyopneumothorax, right trapped lung and post-decortication status. However, due to the fragile nature of the tissue and the existence of vascular adhesions, it was decided to choose "physiological lung exclusion" by separating the affected lung from the tracheobronchial tree by cutting the bronchus and tying off the pulmonary artery, without removing any lung tissue, while keeping the pulmonary veins intact. The present report highlights the challenges faced, the multidisciplinary approach employed, and the successful surgical outcome, underscoring the importance of collaborative management. [ABSTRACT FROM AUTHOR]

The association between frailty and health-related quality of life (HRQoL) among Asian patients with liver cirrhosis and sarcopenia remains largely unexplored. To address this knowledge gap, we conducted a cross-sectional study involving individuals aged 32 to 69 years, all diagnosed with liver cirrhosis. The chronic liver disease questionnaire (CLDQ) was used to assess HR-QoL, the CLDQ score was used as an outcome to measure the factors related to HR-QoL, and the liver frailty index (LFI) was used to assess the frailty status. The association between the frailty status and the CLDQ summary scales was investigated using the correlation coefficient and multiple regression analyses. A total of 138 patients in the frail (n = 62) and non-frail (n = 76) groups with (alcohol: 97; viral: 24; autoimmune: 17; and cryptogenic: 12) were included in the study. Age, CTP score, and model for end-stage liver disease (MELD) sodium were significantly higher in the frail group. In the CLDQ domains, there was a significant difference between the frail and non-frail groups (p value = 0.001). In health-related quality-of-life summary measures, there was a strong negative correlation between frailty and the scores for activities, emotional function, and fatigue (p value = 0.001). When comparing frail to non-frail patients, these characteristics demonstrated significantly increased odds as indicated by their adjusted odds ratios: OR 3.339 (p value = 0.013), OR 3.998 (p value = 0.006), and OR 4.626 (p value = 0.002), respectively. [ABSTRACT FROM AUTHOR]

Background: The COVID-19 pandemic has caused unprecedented human health consequences. It is imperative to understand the society's awareness toward knowledge, attitude, and practice (KAP) level and the extent of measures required by health authorities. Aims and Objective: The aim of the study was to assess the KAP of the general public of India on COVID-19. In this study, a web-based cross-sectional survey was conducted between March 10 and April 18, 2020. Materials and Method: A 19-item questionnaire was generated using Google Forms and distributed through social media networks via snowball sampling technique. The Chi-square test was used to compare categorical data, and multiple linear regression was used to identify factors influencing KAP. Result: Among 7978 participants, the overall KAP score was 80.64%, 97.33%, and 93.8%, respectively. In multiple linear regression analysis, male gender (β = 0.036: P < 0.001), urban population (β = 0.006: P < 0.002), higher education (β = 0.029: P < 0.001), and higher occupation (β = 0.002: P = 0.05) were associated significantly with high knowledge score. There was a positive significant correlation between knowledge and attitude, knowledge and practice, and attitude and practice. Conclusion: The KAP level among the general public was adequate, however there is a necessity to target specific category population with tailored health education program to ameliorate the level of knowledge and attitude. knowledge and attitude. [ABSTRACT FROM AUTHOR]

Objective: This study aimed to investigate the burden of the COVID-19 pandemic on tuberculosis (TB) trends, patient demographics, disease types and hospitalisation duration within the Respiratory Medicine Department over three distinct phases: pre-COVID-19, COVID-19 and post-COVID-19., Design: Retrospective analysis using electronic medical records of patients with TB admitted between June 2018 and June 2023 was done to explore the impact of COVID-19 on patients with TB. The study employed a meticulous segmentation into pre-COVID-19, COVID-19 and post-COVID-19 eras., Setting: National Institute of Medical Science Hospital in Jaipur, Rajasthan, India., Primary and Secondary Outcome Measures: Primary outcome includes patients admitted to the Respiratory Medicine Department of the hospital and secondary outcome involves the duration of hospital stay., Results: The study encompassed 1845 subjects across the three eras, revealing a reduction in TB incidence during the post-COVID-19 era compared with the pre-COVID-19 period (p<0.01). Substantial demographic shifts were observed, with 5.2% decline in TB incidence among males in the post-COVID-19 era (n=529) compared with the pre-COVID-19 era (n=606). Despite the decrease, overall TB incidence remained significantly higher in males (n=1460) than females (n=385), with consistently elevated rates in rural (65.8%) as compared with the urban areas (34.2%). Extended hospital stays were noted in the post-COVID-19 era compared with the pre-COVID-19 era (p<0.01)., Conclusion: The study underscores the influence of the COVID-19 pandemic on the TB landscape and hospitalisation dynamics. Notably, patient burden of TB declined during the COVID-19 era, with a decline in the post-COVID-19 era compared with the pre-COVID-19 era. Prolonged hospitalisation in the post-COVID-19 period indicates the need for adaptive healthcare strategies and the formulation of public health policies in a post-pandemic context. These findings contribute to a comprehensive understanding of the evolving TB scenario, emphasising the necessity for tailored healthcare approaches in the aftermath of a global health crisis., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)

Background: - Health care workers are under a substantial level of psychological impact due to the risk of exposure, workload and moral dilemmas as the nation is on upsurge of COVID-19 cases. Since there are limited research available on this issue from India, we have decided to conduct an online survey to evaluate mental health outcome and professional quality of life among healthcare worker during COVID-19 pandemic., Methods: - From 25th May to 10th June 2020, a web-based (FRONT-LINE COVID) survey was conducted. Impact of event revised (IES-R), Connor-Davidson Resilience scale (CD-RISC) and Professional Quality of life (ProQOL) and Feeling related questions were administered among Healthcare workers from different departments of hospital., Results: - Among the respondents,218 (52.1%) belongs from the low-risk unit and 200 (47.9%) from the 'high-risk unit' including a higher proportion of nurses 191 (45.7%), female 282(67.5%), aged 31-40 years (48.3%), and married 220 (52.6%). Overall female nurses (P=>0.001), doctors (P=0.02) those were working in an emergency unit (P= <0.001) were at greater risk of psychological distress. Middle-aged (31- 40 years) had a higher level of resilience (p=0.02) contrast to this; working in COVID-19 unit was associated with a lower scale of resilience (p=0.009). Resilience and QoL were an important predictor for psychological distress., Conclusion: - Results implicate interventions for stress management and social support among medical staff working in the pandemic., (© 2020 Published by Elsevier Masson SAS.)