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1. Contributors

Author

Ahmed, Tayyaba, primary, Akuthota, Venu, additional, Alleva, Joseph T., additional, Altschuler, Eric L., additional, Amadera, Joao E.D., additional, Amy, Eduardo, additional, Azuh, Ogochukwu, additional, Bach, John R., additional, Bachoura, Patrick J., additional, Baerga-Varela, Luis, additional, Bagay, Leslie, additional, Bang, Moon Suk, additional, Bartels, Matthew N., additional, Bastas, Gerasimos, additional, Bengtson, Keith A., additional, Berry, Tommie, additional, Bhatnagar, Saurabha, additional, Blaustein, David M., additional, Boettcher, Brennan J., additional, Bogie, Kath, additional, Borg, Kristian, additional, Borg-Stein, Joanne, additional, Borgstrom, Haylee E., additional, Bosques, Glendaliz, additional, Brassil, Michelle E., additional, Brault, Jeffrey S., additional, Braza, Diane W., additional, Brown, David P., additional, Burke, David T., additional, Butendieck, Ronald Rolf, additional, Butler, Aaron W., additional, Byram, Kevin, additional, Cabrera, Alison L., additional, Campbell, Melanie E., additional, Campbell, T. Mark, additional, Carayannopoulos, Alexios G., additional, Carter, Gregory T., additional, Chan, Isabel, additional, Chan, Sophia, additional, Chen, Eric T., additional, Cheung, Amanda, additional, Cheville, Andrea, additional, Chew, Kelvin, additional, Chinratanalab, Sallaya, additional, Ciammaichella, Ellia, additional, Cianca, John, additional, Clinchot, Daniel Michael, additional, Colberg, Ricardo E., additional, Craig, Earl J., additional, Cruz, Lisanne C., additional, Cuccurullo, Sara, additional, Custodio, Christian M., additional, Davis, Alan M., additional, Del Toro, David R., additional, Delavaux, Laurent, additional, Di Felice, Francesca, additional, Donovan, Jayne, additional, Donzelli, Sabrina, additional, Dreyer, Susan J., additional, Dudek, Nancy, additional, Dudkiewicz, Israel, additional, Dugan, Sheila A., additional, Eapen, Blessen C., additional, Ebenbichler, Gerold R., additional, El Abd, Omar H., additional, Ellen, Mark I., additional, Ellenberg, Maury, additional, Ellenberg, Michael J., additional, Elson, Lauren, additional, Eng, Christine, additional, Ennis, Jesse D., additional, Ensrud, Erik, additional, Escaldi, Steven, additional, Esser, Stephan M., additional, Fast, Avital, additional, Finnoff, Jonathan T., additional, Forbush, David R., additional, Foye, Patrick M., additional, Fredericson, Michael, additional, Frontera, Joel E., additional, Frontera, Walter R., additional, Gao, Chan, additional, Ghebrendrias, Youhans, additional, Glenn, Mel B., additional, Gnana, Jenoj S., additional, Gonzalez, Peter, additional, Groomes, Thomas E., additional, Grosser, Dawn M., additional, Halperin, Jonathan S., additional, Han, Alex, additional, Hanak, Joseph A., additional, Hanson, Toni J., additional, Hartigan, David E., additional, Herman, Seth D., additional, Herrera, Joseph E., additional, Ho, Chester, additional, Hon, Alice J., additional, Hou, Joan Y., additional, Howard, Timothy, additional, Hubbard, Ryan, additional, Hudgins, Thomas H., additional, Ibanez, Katarzyna, additional, Isaac, Zacharia, additional, Jain, Nitin B., additional, Jaramillo, Carlos A., additional, Jayaram, Prathap, additional, Johns, Jeffery S., additional, Joki, Jaclyn, additional, Joseph, Prathap Jacob, additional, Joyce, Nanette C., additional, Jung, Se Hee, additional, Karimi, Danielle Perret, additional, Kay, Jonathan, additional, Kigner, Stuart, additional, Kile, Todd A., additional, King, John C., additional, Knopp, Hans E., additional, Knowlton, Sasha E., additional, Kortte, Jason H., additional, Kotler, Dana H., additional, Krabak, Brian J., additional, Kupperman, Wyatt, additional, Kurz, Jennifer, additional, Lee, Shi-Uk, additional, Lento, Paul, additional, Lexell, Jan, additional, Lim, Peter A.C., additional, Lin, Cindy Y., additional, Lin, Lei, additional, Lindgren, Karl-August, additional, Mahmood, Umar, additional, Makovicka, Justin L., additional, Makovitch, Steven A., additional, Mansourian, Vartgez K., additional, Marshall, Ben, additional, Yacub Martin, Jennifer N., additional, Matsuo, Koichiro, additional, Maya, Juan Jose, additional, Maybin, A. Simone, additional, McGeary, Donald, additional, McInnis, Kelly C., additional, McIntosh, Peter Melvin, additional, Meleger, Alec L., additional, Micheo, William F., additional, Mimbella, Paolo, additional, Miranda-Comas, Gerardo, additional, Montero, Daniel P., additional, Moore, Brittany J., additional, Mostoufi, S. Ali, additional, Mudgal, Chaitanya S., additional, Negrini, Stefano, additional, Nesathurai, Shanker, additional, O’Neill, Carina Joy, additional, Okafor, Eziamaka Chidi, additional, Origenes, Andrea K., additional, Ortiguera, Cedric J., additional, Osborne, Michael D., additional, Pai, Ajit B., additional, Palmer, Jeffrey B., additional, Parikh, Sagar S., additional, Partyka, Marcin, additional, Patel, Atul T., additional, Patel, Shawn A., additional, Perez, Nicolas, additional, Perry, Dwan, additional, Phillips, Edward M., additional, Pimentel, Daniel C., additional, Pleuhs, Benedikt, additional, Pobre, Thomas E., additional, Pugh, Terrence, additional, Putnam, Alison R., additional, Rainville, James, additional, Ramachandran, V.S., additional, Richardson, Brian E., additional, Ring, David, additional, Rivera-Vega, Alexandra, additional, Rizzo, Thomas D., additional, Rosario-Concepión, Raul A., additional, Rosenberg, Darren C., additional, Rossi, Roger P., additional, Rutkove, Seward B., additional, Sabharwal, Sunil, additional, Sajid, Nourma, additional, Sanchez, Luis A., additional, Santiago, Francisco H., additional, Sarno, Danielle, additional, Scardina, Robert J., additional, Schneider, Byron J., additional, Schneider, Jeffrey C., additional, Sepúlveda, Fernando, additional, Sergent, John, additional, Seslija, Dana, additional, Shah, Vivian P., additional, Sharma, Jyoti, additional, Sharma, Nutan, additional, Sheng, Alex, additional, Shi, Glenn G., additional, Silver, Julie K., additional, Slocum, Chloe, additional, Slovik, David M., additional, Abreu Sosa, Sol M., additional, Spindler, Kurt, additional, Splittgerber, Lauren, additional, Stark, Stacy M., additional, Stein, Joel, additional, Stilp, Sonja K., additional, Stitik, Todd P., additional, Stretanski, Michael F., additional, Stubblefield, Michael D., additional, Subbarao, Bruno S., additional, Taliaferro, John, additional, Tapia, Rebecca N., additional, Thomas, Ann-Marie, additional, Tran, Jiaxin, additional, Tribuzio, Bianca A., additional, Trudel, Guy, additional, Uustal, Heikki, additional, Vallarino, Ramon, additional, Verduzco-Gutierrez, Monica, additional, Verma, Ankur, additional, Vora, Ariana, additional, Wainberg, Michael C., additional, Wang, Roger, additional, Weiss, Jay M., additional, Weiss, Lyn D., additional, Welch, Sarah A., additional, Wexler, David, additional, Wieting, J. Michael, additional, Wilkins, Allen Neil, additional, Yang, Aaron Jay, additional, Zaina, Fabio, additional, and Zhao, Meijuan, additional

Published
2020
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7. Report of the NIH Task Force on Research Standards for Chronic Low Back Pain

Author

Deyo, Richard A., Dworkin, Samuel F., Amtmann, Dagmar, Andersson, Gunnar, Borenstein, David, Carragee, Eugene, Carrino, John, Chou, Roger, Cook, Karon, DeLitto, Anthony, Goertz, Christine, Khalsa, Partap, Loeser, John, Mackey, Sean, Panagis, James, Rainville, James, Tosteson, Tor, Turk, Dennis, Von Korff, Michael, and Weiner, Debra K.

Published
2014
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20. Does this lower adult with lower extremity pain have the clinical syndrome of lumbar spinal stenosis?

Author

Suri, Pradeep, Rainville, James, Kalichman, Leonid, and Katz, Jeffrey N.

Subjects
Low back pain -- Diagnosis, Low back pain -- Care and treatment, Radiography -- Usage, Spinal canal -- Stenosis, Spinal canal -- Diagnosis, Spinal canal -- Care and treatment
Abstract

A study was conducted to evaluate whether a clinical examination for lower back pain is suitable enough for the diagnosis of clinical syndrome of lumbar spinal stenosis (LSS). Results indicated that such diagnosis requires the appropriate clinical picture and radiographic findings and a combination of findings are generally useful in diagnosis.

Published
2010

28. Contributors

Author

Akuthota, Venu, primary, Alleva, Joseph T., additional, Amy, Eduardo, additional, Atkinson, Karen, additional, Audette, Joseph F., additional, Bach, John R., additional, Bailey, Allison, additional, Baima, Jennifer, additional, Banerjee, Sarah S., additional, Bang, Moon Suk, additional, Banks, Norman L., additional, Barr, Karen P., additional, Belanger, Heather G., additional, Bienkowski, Peter, additional, Black-Schaffer, Randie M., additional, Blount, Philip J., additional, Bockenek, William L., additional, Bogie, Kath, additional, Borg, Kristian, additional, Borg-Stein, Joanne, additional, Bowen, Jay E., additional, Brault, Jeffrey S., additional, Braverman, Steven E., additional, Braza, Diane W., additional, Brennan, Patrick, additional, Brodie, Jeffrey T., additional, Burke, David, additional, Caban, Mabel E., additional, Carayannopoulos, Alexios, additional, Cassidy, Charles, additional, Cassius, David A., additional, Cheville, Andrea, additional, Chew, Kelvin, additional, Childers, Martin K., additional, Chow, Chien, additional, Chung, Victor, additional, Clinchot, Daniel M., additional, Cohen, Isaac, additional, Craig, Earl J., additional, Curtis, Christine, additional, Dave, Jatin, additional, Davis, Alan M., additional, Del Toro, David R., additional, Devine, Jennifer, additional, Dillingham, Timothy R., additional, Dreyer, Susan J., additional, Dudek, Nancy, additional, Dugan, Sheila, additional, Ebenbichler, Gerold R., additional, Abd, Omar El, additional, Ellenberg, Maury, additional, Ensrud, Erik, additional, Fast, Avital, additional, Feldman, Jeffery B., additional, Fitzgerald, Brian T., additional, Foster, Leslie S., additional, Foye, Patrick M., additional, Fredericson, Michael, additional, Gittler, Michelle, additional, Glenn, Mel B., additional, Gonzalez, Peter, additional, Grosser, Dawn M., additional, Guo, H. Michael, additional, Gupta, Navneet, additional, Hacker, Hope S., additional, Hanada, Ed, additional, Hanson, Toni J., additional, Harrington, Amanda L., additional, Hatch, Sandra S., additional, Hecht, Melvyn L., additional, Ho, Chester H., additional, Hoch, Anne Z., additional, Honet, Joseph C., additional, Hudgins, Thomas H., additional, Humayun, Faiza, additional, Imamura, Marta, additional, Tomikawa Imamura, Satiko, additional, Isaac, Zacharia, additional, Jouve, Cristin, additional, Jung, Se Hee, additional, Kaplan, Robert J., additional, Kay, Jonathan, additional, Kaynan, Ayal M., additional, Keplinger, Florian S., additional, Kile, Todd A., additional, King, John C., additional, Knight, Ricardo, additional, Kortte, Jason H., additional, Krabak, Brian J., additional, Krivickas, Lisa S., additional, Krug, Robert J., additional, Latlief, Gail A., additional, Lee, Elise H., additional, Lee, Sammy M., additional, Lee, Shi-Uk, additional, Lee, Yong-Tae, additional, Lennard, Ted A., additional, Lento, Paul, additional, Lim, Peter A.C., additional, Lindgren, Karl-August, additional, Loder, Elizabeth, additional, Maguire, Sandra, additional, Malanga, Gerard A., additional, Mashey, Katherine, additional, Matsuo, Koichiro, additional, McInnis, Kelly, additional, McIntosh, Peter M., additional, Meleger, Alec L., additional, Micheli, Lyle J., additional, Micheo, William, additional, Moore, William, additional, Mostoufi, S. Ali, additional, Mudgal, Chaitanya S., additional, Mulford, Gregory J., additional, Nesathurai, Shanker, additional, Nolla, José M., additional, O'Neill, Carina J., additional, Osborne, Michael D., additional, Packel, Lora Beth, additional, Palmer, Jeffrey B., additional, Pasquina, Paul F., additional, Patel, Atul, additional, Perkash, Inder, additional, Phillips, Edward M., additional, Pobre, Thomas E., additional, Pollack, Elliot, additional, Rahman, Mahboob U., additional, Rainville, James, additional, Ramos, Edwardo, additional, Ring, David, additional, Rosenberg, Darren, additional, Riutta, Justin, additional, Rizzo, Thomas D., additional, Rutkove, Seward B., additional, Sabharwal, Sunil, additional, Santiago, Francisco H., additional, Scardina, Robert J., additional, Schaufele, Michael K., additional, Schneider, Jeffrey C., additional, Scholten, Joel D., additional, Scott, Steven G., additional, Segal, Miriam, additional, Shah, Vivek M., additional, Shahban, Lena, additional, Sharma, Nutan, additional, Silver, Julie K., additional, Silver, Kenneth H., additional, Singh, Ajay K., additional, Singla, Aneesh, additional, Sipple, Daniel, additional, Skerker, Robert S., additional, Slovik, David M., additional, Sokolof, Jonas, additional, Spinelli, James, additional, Stein, Joel, additional, Stein, Meryl, additional, Stilp, Sonja K., additional, Stitik, Todd P., additional, Storm, Seneca A., additional, Stretanski, Michael F., additional, Thomas, Ann-Marie, additional, Thomas, Mark A., additional, Thompson, Anita, additional, Trudel, Guy, additional, Umphrey, Gregory L., additional, Vallarino, Roman, additional, Vanderploeg, Rodney D., additional, Vetter, Carole S., additional, Vora, Ariana, additional, Walsh, Aimee H., additional, Wang, David, additional, Wang, Yumei, additional, Weiss, Jay M., additional, Weiss, Lyn D., additional, Wexler, David, additional, Wierbicky, Jane, additional, Wieting, J. Michael, additional, Wilkins, Allen N., additional, and Zhao, Meijuan, additional

Published
2008
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35. What can the history and physical examination tell us about low back pain?

Author

Deyo, Richard A., Rainville, James, and Kent, Daniel L.

Subjects
Backache -- Diagnosis, Periodic health examinations -- Methods, Medical history taking -- Methods
Abstract

A careful history and physical examination can determine the cause of pain, whether surgery will be required to relieve it and whether the patient has any psychological problems that may interfere with treatment. Low back pain is the second most common reason for patient office visits. Though 70% of adults have suffered from low back pain, it seldom lasts more than two weeks. Up to 85% of patients with low back pain cannot be precisely diagnosed because symptoms, physiological changes and imaging results do not correlate. An X-ray is no longer recommended for every patient because it does not always contribute to the diagnosis, and exposes the patient to gonadal irradiation. It is recommended only if there is evidence of a neurologic disorder, in patients over age 50 or under age 20, and in patients with fever, trauma or signs of cancer.

Published
1992

39. Acute low back pain is marked by variability: An internet-based pilot study

Author

Katz Jeffrey N, Fitzmaurice Garrett M, Rainville James, Suri Pradeep, Jamison Robert N, Martha Julia, Hartigan Carol, Limke Janet, Jouve Cristin, and Hunter David J

Subjects
Diseases of the musculoskeletal system, RC925-935
Abstract

Abstract Background Pain variability in acute LBP has received limited study. The objectives of this pilot study were to characterize fluctuations in pain during acute LBP, to determine whether self-reported 'flares' of pain represent discrete periods of increased pain intensity, and to examine whether the frequency of flares was associated with back-related disability outcomes. Methods We conducted a cohort study of acute LBP patients utilizing frequent serial assessments and Internet-based data collection. Adults with acute LBP (lasting ≤3 months) completed questionnaires at the time of seeking care, and at both 3-day and 1-week intervals, for 6 weeks. Back pain was measured using a numerical pain rating scale (NPRS), and disability was measured using the Oswestry Disability Index (ODI). A pain flare was defined as 'a period of increased pain lasting at least 2 hours, when your pain intensity is distinctly worse than it has been recently'. We used mixed-effects linear regression to model longitudinal changes in pain intensity, and multivariate linear regression to model associations between flare frequency and disability outcomes. Results 42 of 47 participants (89%) reported pain flares, and the average number of discrete flare periods per patient was 3.5 over 6 weeks of follow-up. More than half of flares were less than 4 hours in duration, and about 75% of flares were less than one day in duration. A model with a quadratic trend for time best characterized improvements in pain. Pain decreased rapidly during the first 14 days after seeking care, and leveled off after about 28 days. Patients who reported a pain flare experienced an almost 3-point greater current NPRS than those not reporting a flare (mean difference [SD] 2.70 [0.11]; p < 0.0001). Higher flare frequency was independently associated with a higher final ODI score (ß [SE} 0.28 (0.08); p = 0.002). Conclusions Acute LBP is characterized by variability. Patients with acute LBP report multiple distinct flares of pain, which correspond to discrete increases in pain intensity. A higher flare frequency is associated with worse disability outcomes.

Published
2011
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40. Does lumbar spinal degeneration begin with the anterior structures? A study of the observed epidemiology in a community-based population

Author

Jarvik Jeffrey G, Hunter David J, Miyakoshi Asako, Suri Pradeep, Rainville James, Guermazi Ali, Li Ling, and Katz Jeffrey N

Subjects
degenerative cascade, degeneration, disk, facet joint, arthritis, lumbar, spine, Diseases of the musculoskeletal system, RC925-935
Abstract

Abstract Background- Prior studies that have concluded that disk degeneration uniformly precedes facet degeneration have been based on convenience samples of individuals with low back pain. We conducted a study to examine whether the view that spinal degeneration begins with the anterior spinal structures is supported by epidemiologic observations of degeneration in a community-based population. Methods- 361 participants from the Framingham Heart Study were included in this study. The prevalences of anterior vertebral structure degeneration (disk height loss) and posterior vertebral structure degeneration (facet joint osteoarthritis) were characterized by CT imaging. The cohort was divided into the structural subgroups of participants with 1) no degeneration, 2) isolated anterior degeneration (without posterior degeneration), 3) combined anterior and posterior degeneration, and 4) isolated posterior degeneration (without anterior structure degeneration). We determined the prevalence of each degeneration pattern by age group < 45, 45-54, 55-64, ≥65. In multivariate analyses we examined the association between disk height loss and the response variable of facet joint osteoarthritis, while adjusting for age, sex, BMI, and smoking. Results- As the prevalence of the no degeneration and isolated anterior degeneration patterns decreased with increasing age group, the prevalence of the combined anterior/posterior degeneration pattern increased. 22% of individuals demonstrated isolated posterior degeneration, without an increase in prevalence by age group. Isolated posterior degeneration was most common at the L5-S1 and L4-L5 spinal levels. In multivariate analyses, disk height loss was independently associated with facet joint osteoarthritis, as were increased age (years), female sex, and increased BMI (kg/m2), but not smoking. Conclusions- The observed epidemiology of lumbar spinal degeneration in the community-based population is consistent with an ordered progression beginning in the anterior structures, for the majority of individuals. However, some individuals demonstrate atypical patterns of degeneration, beginning in the posterior joints. Increased age and BMI, and female sex may be related to the occurrence of isolated posterior degeneration in these individuals.

Published
2011
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41. Bias in the physical examination of patients with lumbar radiculopathy

Author

Katz Jeffrey N, Hunter David J, Suri Pradeep, Li Ling, and Rainville James

Subjects
Diseases of the musculoskeletal system, RC925-935
Abstract

Abstract Background No prior studies have examined systematic bias in the musculoskeletal physical examination. The objective of this study was to assess the effects of bias due to prior knowledge of lumbar spine magnetic resonance imaging findings (MRI) on perceived diagnostic accuracy of the physical examination for lumbar radiculopathy. Methods This was a cross-sectional comparison of the performance characteristics of the physical examination with blinding to MRI results (the 'independent group') with performance in the situation where the physical examination was not blinded to MRI results (the 'non-independent group'). The reference standard was the final diagnostic impression of nerve root impingement by the examining physician. Subjects were recruited from a hospital-based outpatient specialty spine clinic. All adults age 18 and older presenting with lower extremity radiating pain of duration ≤ 12 weeks were evaluated for participation. 154 consecutively recruited subjects with lumbar disk herniation confirmed by lumbar spine MRI were included in this study. Sensitivities and specificities with 95% confidence intervals were calculated in the independent and non-independent groups for the four components of the radiculopathy examination: 1) provocative testing, 2) motor strength testing, 3) pinprick sensory testing, and 4) deep tendon reflex testing. Results The perceived sensitivity of sensory testing was higher with prior knowledge of MRI results (20% vs. 36%; p = 0.05). Sensitivities and specificities for exam components otherwise showed no statistically significant differences between groups. Conclusions Prior knowledge of lumbar MRI results may introduce bias into the pinprick sensory testing component of the physical examination for lumbar radiculopathy. No statistically significant effect of bias was seen for other components of the physical examination. The effect of bias due to prior knowledge of lumbar MRI results should be considered when an isolated sensory deficit on examination is used in medical decision-making. Further studies of bias should include surgical clinic populations and other common diagnoses including shoulder, knee and hip pathology.

Published
2010
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43. Colaboradores

Author

Ahmed, Tayyaba, Akuthota, Venu, Alleva, Joseph T., Altschuler, Eric L., Amadera, Joao E.D., Amy, Eduardo, Azuh, Ogochukwu, Bach, John R., Bachoura, Patrick J., Baerga-Varela, Luis, Bagay, Leslie, Bang, Moon Suk, Bartels, Matthew N., Bastas, Gerasimos, Bengtson, Keith A., Berry, Tommie, Jr., Bhatnagar, Saurabha, Blaustein, David M., Boettcher, Brennan J., Bogie, Kath, Borg, Kristian, Borg-Stein, Joanne, Borgstrom, Haylee E., Bosques, Glendaliz, Brassil, Michelle E., Brault, Jeffrey S., Braza, Diane W., Brown, David P., Burke, David T., Butendieck, Ronald Rolf, Butler, Aaron W., Byram, Kevin, Cabrera, Alison L., Campbell, Melanie E., Campbell, T. Mark, Carayannopoulos, Alexios G., Carter, Gregory T., Chan, Isabel, Chan, Sophia, Chen, Eric T., Cheung, Amanda, Cheville, Andrea, Chew, Kelvin, Chinratanalab, Sallaya, Ciammaichella, Ellia, Cianca, John, Clinchot, Daniel Michael, Colberg, Ricardo E., Craig, Earl J., Cruz, Lisanne C., Cuccurullo, Sara, Custodio, Christian M., Davis, Alan M., Del Toro, David R., Delavaux, Laurent, Di Felice, Francesca, Donovan, Jayne, Donzelli, Sabrina, Dreyer, Susan J., Dudek, Nancy, Dudkiewicz, Israel, Dugan, Sheila A., Eapen, Blessen C., Ebenbichler, Gerold R., Abd, Omar H. El, Ellen, Mark I., Ellenberg, Maury, Ellenberg, Michael J., Elson, Lauren, Eng, Christine, Ennis, Jesse D., Ensrud, Erik, Escaldi, Steven, Esser, Stephan M., Fast, Avital, Finnoff, Jonathan T., Forbush, David R., Foye, Patrick M., Fredericson, Michael, Frontera, Joel E., Frontera, Walter R., Gao, Chan, Ghebrendrias, Youhans, Glenn, Mel B., Gnana, Jenoj S., Gonzalez, Peter, Groomes, Thomas E., Grosser, Dawn M., Halperin, Jonathan S., Han, Alex, Hanak, Joseph A., Hanson, Toni J., Hartigan, David E., Herman, Seth D., Herrera, Joseph E., Ho, Chester, Hon, Alice J., Hou, Joan Y., Howard, Timothy, Hubbard, Ryan, Hudgins, Thomas H., Ibanez, Katarzyna, Isaac, Zacharia, Jain, Nitin B., Jaramillo, Carlos A., Jayaram, Prathap, Johns, Jeffery S., Joki, Jaclyn, Joseph, Prathap Jacob, Joyce, Nanette C., Jung, Se Hee, Karimi, Danielle Perret, Kay, Jonathan, Kigner, Stuart, Kile, Todd A., King, John C., Knopp, Hans E., Knowlton, Sasha E., Kortte, Jason H., Kotler, Dana H., Krabak, Brian J., Kupperman, Wyatt, Kurz, Jennifer, Lee, Shi-Uk, Lento, Paul, Lexell, Jan, Lim, Peter A.C., Lin, Cindy Y., Lin, Lei, Lindgren, Karl-August, Mahmood, Umar, Makovicka, Justin L., Makovitch, Steven A., Mansourian, Vartgez K., Marshall, Ben, Martin, Jennifer N. Yacub, Matsuo, Koichiro, Maya, Juan Jose, Maybin, A. Simone, McGeary, Donald, McInnis, Kelly C., McIntosh, Peter Melvin, Meleger, Alec L., Micheo, William F., Mimbella, Paolo, Miranda-Comas, Gerardo, Montero, Daniel P., Moore, Brittany J., Mostoufi, S. Ali, Mudgal, Chaitanya S., Negrini, Stefano, Nesathurai, Shanker, O’Neill, Carina Joy, Okafor, Eziamaka Chidi, Origenes, Andrea K., Ortiguera, Cedric J., Osborne, Michael D., Pai, Ajit B., Palmer, Jeffrey B., Parikh, Sagar S., Partyka, Marcin, Patel, Atul T., Patel, Shawn A., Perez, Nicolas, Perry, Dwan, Phillips, Edward M., Pimentel, Daniel C., Pleuhs, Benedikt, Pobre, Thomas E., Pugh, Terrence, Putnam, Alison R., Rainville, James, Ramachandran, V.S., Richardson, Brian E., Ring, David, Rivera-Vega, Alexandra, Rizzo, Thomas D., Jr., Rosario-Concepción, Raul A., Rosenberg, Darren C., Rossi, Roger P., Rutkove, Seward B., Sabharwal, Sunil, Sajid, Nourma, Sanchez, Luis A., Santiago, Francisco H., Sarno, Danielle, Scardina, Robert J., Schneider, Byron J., Schneider, Jeffrey C., Sepúlveda, Fernando, Sergent, John, Seslija, Dana, Shah, Vivian P., Sharma, Jyoti, Sharma, Nutan, Sheng, Alex, Shi, Glenn G., Silver, Julie K., Slocum, Chloe, Slovik, David M., Sosa, Sol M. Abreu, Spindler, Kurt, Splittgerber, Lauren, Stark, Stacy M., Stein, Joel, Stilp, Sonja K., Stitik, Todd P., Stretanski, Michael F., Stubblefield, Michael D., Subbarao, Bruno S., Taliaferro, John, Tapia, Rebecca N., Thomas, Ann-Marie, Tran, Jiaxin, Tribuzio, Bianca A., Trudel, Guy, Uustal, Heikki, Vallarino, Ramon, Jr., Verduzco-Gutierrez, Monica, Verma, Ankur, Vora, Ariana, Wainberg, Michael C., Wang, Roger, Weiss, Jay M., Weiss, Lyn D., Welch, Sarah A., Wexler, David, Wieting, J. Michael, Wilkins, Allen Neil, Yang, Aaron Jay, Zaina, Fabio, and Zhao, Meijuan

Published
2020
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45. Quantitative Assessment of Abdominal Aortic Calcification and Disk Height Loss: The Framingham Study

Author

Suri, Pradeep, Hunter, David J., Rainville, James, Guermazi, Ali, and Katz, Jeffrey N.

Subjects
110322 - Rheumatology and Arthritis [FoR], spine
Abstract

Background context Vascular disease has been proposed as a risk factor for disc height loss (DHL). Purpose To examine the relationship between quantitative measures of abdominal aortic calcifications (AACs) as a marker of vascular disease, and DHL, on computed tomography (CT). Study design Cross-sectional study in a community-based population. Patient sample Four hundred thirty-five participants from the Framingham Heart Study. Outcome measures Quantitative AAC scores assessed by CT were grouped as tertiles of “no” (reference), “low,” and “high” calcification. Disc height loss was evaluated on CT reformations using a four-grade scale. For analytic purposes, DHL was dichotomized as moderate DHL of at least one level at L2–S1 versus less than moderate or no DHL. Methods We examined the association of AAC and DHL using logistic regression before and after adjusting for cardiovascular risk factors and before and after adjusting for age, sex, and body mass index (BMI). Results In crude analyses, low AAC (odds ratio [OR], 2.05 [1.27–3.30]; p=.003) and high AAC (OR, 2.24 [1.38–3.62]; p=.001) were strongly associated with DHL, when compared with the reference group of no AAC. Diabetes, hypercholesterolemia, hypertension, and smoking were not associated with DHL and did not attenuate the observed relationship between AAC and DHL. Adjustment for age, sex, and BMI markedly attenuated the associations between DHL and low AAC (OR, 1.20 [0.69–2.09]; p=.51) and high AAC (OR, 0.74 [0.36–1.53]; p=.42). Conclusions Abdominal aortic calcification was associated with DHL in this community-based population. This relationship was independent of cardiovascular risk factors. However, the association of AAC with DHL was explained by the effects of age, sex, and BMI.

Published
2012

47. Report of the NIH Task Force on Research Standards for Chronic Low Back Pain

Author

Deyo, Richard A., primary, Dworkin, Samuel F., additional, Amtmann, Dagmar, additional, Andersson, Gunnar, additional, Borenstein, David, additional, Carragee, Eugene, additional, Carrino, John, additional, Chou, Roger, additional, Cook, Karon, additional, Delitto, Anthony, additional, Goertz, Christine, additional, Khalsa, Partap, additional, Loeser, John, additional, Mackey, Sean, additional, Panagis, James, additional, Rainville, James, additional, Tosteson, Tor, additional, Turk, Dennis, additional, Von Korff, Michael, additional, and Weiner, Debra K., additional

Published
2015
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48. Report of the NIH Task Force on Research Standards for Chronic Low Back Pain

Author

Deyo, Richard A., primary, Dworkin, Samuel F., additional, Amtmann, Dagmar, additional, Andersson, Gunnar, additional, Borenstein, David, additional, Carragee, Eugene, additional, Carrino, John, additional, Chou, Roger, additional, Cook, Karon, additional, DeLitto, Anthony, additional, Goertz, Christine, additional, Khalsa, Partap, additional, Loeser, John, additional, Mackey, Sean, additional, Panagis, James, additional, Rainville, James, additional, Tosteson, Tor, additional, Turk, Dennis, additional, Korff, Michael Von, additional, and Weiner, Debra K., additional

Published
2014
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49. Focus Article Report of the NIH Task Force on Research Standards for Chronic Low Back Pain

Author

Deyo, Richard A., primary, Dworkin, Samuel F., additional, Amtmann, Dagmar, additional, Andersson, Gunnar, additional, Borenstein, David, additional, Carragee, Eugene, additional, Carrino, John, additional, Chou, Roger, additional, Cook, Karon, additional, DeLitto, Anthony, additional, Goertz, Christine, additional, Khalsa, Partap, additional, Loeser, John, additional, Mackey, Sean, additional, Panagis, James, additional, Rainville, James, additional, Tosteson, Tor, additional, Turk, Dennis, additional, Von Korff, Michael, additional, and Weiner, Debra K., additional

Published
2014
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