26 results on '"Rai JK"'
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2. Optimized inverse kinematics modeling and joint angle prediction for six-degree-of-freedom anthropomorphic robots with Explainable AI.
- Author
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Joshi RC, Rai JK, Burget R, and Dutta MK
- Abstract
Inverse kinematics, crucial in robotics, involves computing joint configurations to achieve specific end-effector positions and orientations. This task is particularly complex for six-degree-of-freedom (six-DoF) anthropomorphic robots due to complicated mathematical equations, nonlinear behaviours, multiple valid solutions, physical constraints, non-generalizability and computational demands. The primary contribution of this work is to address the complex inverse kinematics problem for six-DoF anthropomorphic robots through the systematic exploration of AI models. This study involves rigorous evaluation and Bayesian optimization for hyperparameter tuning to identify the optimal regressor, balancing both accuracy and computational efficiency. Utilizing five-fold cross-validation on a publicly available dataset, the selected model demonstrates exceptional performance in predicting six joint angles for end effector configuration, yielding an average mean square error of 1.934 × 10
-3 to 3.522 × 10-3 . Its computational efficiency, with a prediction time of approximately 1.25 ms per sample, makes it a practical choice. Additionally, the study employs Explainable AI, using SHAP (SHapley Additive exPlanations) analysis to gain an understanding of feature importance. This analysis not only enhances model interpretability but also reaffirms the efficacy in this challenging multi-input multi-output predictive task. This research advances state-of-the-art models and neural networks by prioritizing computational efficiency alongside accuracy-a critical yet often overlooked factor. Pioneering a significant advancement in anthropomorphic robot kinematics, it balances accuracy and efficiency, offering practical robotic automation solutions., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 ISA. Published by Elsevier Ltd. All rights reserved.)- Published
- 2024
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3. Base rates of failure on various performance validity tests as a function of age in adults referred for neuropsychological assessment.
- Author
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Rai JK, Gervais RO, Rodriguez N, and Erdodi LA
- Subjects
- Humans, Adult, Male, Female, Middle Aged, Aged, Young Adult, Adolescent, Age Factors, Reproducibility of Results, Psychometrics, Malingering diagnosis, Malingering psychology, Neuropsychological Tests statistics & numerical data
- Abstract
This study aimed to investigate the relationship between age and base rates of failure (BR
Fail ) on various performance validity tests (PVTs) administered in medical-legal settings. Archival data were analyzed from 3,297 adults (Mage = 42.3 years; Meducation = 11.2) referred for psychological or neuropsychological assessments in a medical-legal or forensic civil disability context who passed the Word Memory Test. BRFail on 10 PVTs (three freestanding and seven embedded) were reported at multiple cutoffs across five age groups ranging from 16 years to 69 years. BRFail increased with age on most embedded PVTs, with a couple of notable exceptions. Reliable Digit Span was unrelated to age at ≤6 but produced elevated BRFail among older examinees at ≤7. Within freestanding PVTs, a positive relationship emerged between age and BRFail on most instruments/cutoffs. Older age is associated with an increased risk of false positive errors on many embedded PVTs that rely on raw scores. Although freestanding PVTs tend to be more resistant to the effects of age, several commonly used cutoffs may still produce increased false positive rates in older examinees. Taken together, results suggest that PVT scores should be interpreted in the context of patient characteristics, in an evidence-based manner, rather than by rigidly applying omnibus cutoffs. (PsycInfo Database Record (c) 2024 APA, all rights reserved).- Published
- 2024
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4. The impact of the decomposition process of shallow graves on soil mite abundance.
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Rai JK, Pickles BJ, and Perotti MA
- Subjects
- Animals, Burial, Cadaver, Humans, Insecta, Postmortem Changes, Swine, Mites, Soil chemistry
- Abstract
Burial of a cadaver results in a slower decomposition rate, due to more stable below-ground temperatures and restricted access to necrophagous insects. In such circumstances, analysis of the soil mesofauna, with emphasis on mites (Acari) may be more valuable in time-of-death estimations. The production of volatile organic compounds of cadaveric decay results in changes, especially in the soil pH, which in turn would affect the abundance and diversity of the associated mites. In general, the effects of decomposition and the consequently altered pH levels on the abundance of mites in shallow graves, as well as the effects of fluctuating above-ground environmental parameters (temperature, relative humidity, and precipitation) remain unknown. Here, we found that the decay of three pig cadavers buried in shallow graves (<30 cm below) caused a significant increase in the soil pH throughout decomposition, from neutral to alkaline. Cadaver decay attracted an abundance of mites: with 300 mites collected from the three pig cadavers compared to 129 from the control soil samples at the same depth. Mites rapidly became more abundant in cadaver-associated soils than in control soils after the fresh stage. Increasing soil pH had a positive impact on the abundance of mites in graves and there was a significant interaction between cadaver body temperature and soil pH. Above-ground fluctuations in temperature, relative humidity, and precipitation were found to have no significant direct effect on mite abundance in grave or control soils., (© 2021 The Authors. Journal of Forensic Sciences published by Wiley Periodicals LLC on behalf of American Academy of Forensic Sciences.)
- Published
- 2022
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5. Assemblages of Acari in shallow burials: mites as markers of the burial environment, of the stage of decay and of body-cadaver regions.
- Author
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Rai JK, Pickles BJ, and Perotti MA
- Subjects
- Animals, Biodiversity, Burial, Cadaver, Soil, Mites
- Abstract
The burial of a cadaver results in reduced arthropod activity and disruptions in colonisation patterns. Here, the distribution and diversity of mite taxa was studied across decomposition stages of shallowly buried pig carcasses (Sus scrofa domesticus). In total 300 mites (88 species) were collected from three pig shallow graves compared to 129 mites (46 species) from control (bare) soil samples at the same depth. A successional pattern of Acari higher taxa and families was observed, and species richness and biodiversity fluctuated throughout decomposition, whereas active decay showed the greatest biodiversity. Mesostigmata mites were the most abundant in 'cadaver soils' with a significant difference in the abundance of Parasitidae mites, whereas Oribatida mites (true soil mites) were the most abundant in control soils. Certain mite species were significantly associated with decay stages: Cornigamasus lunaris with 'bloated', Gamasodes spiniger with 'active', Eugamasus sp. and Lorryia reticulata with 'advanced', and Macrocheles matrius and Ramusella clavipectinata in 'dry'. Scheloribates laevigatus was a marker of bare soil at a shallow depth and Vulgoramasus remberti of buried decomposition, not specific to any decay stage. Analysis of mite assemblages associated with head, torso and posterior body showed that Parasitus evertsi and M. matrius are attracted to beneath the thighs, whereas L. reticulata to beneath the head. This study highlights the value of mites as indicator species of decomposition and its stages, confirming (1) a succession of Acari on buried remains and (2) species specificity to body regions., (© 2021. The Author(s).)
- Published
- 2021
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6. Impact of criterion measures on the classification accuracy of TOMM-1.
- Author
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Rai JK and Erdodi LA
- Subjects
- Adult, Educational Status, Humans, Memory Disorders, Neuropsychological Tests, Reproducibility of Results, Malingering diagnosis, Memory and Learning Tests
- Abstract
This study was designed to examine the effect of various criterion measures on the classification accuracy of Trial 1 of the Test of Memory Malingering (TOMM-1), a free-standing performance validity test (PVT). Archival data were collected from a case sequence of 91 ( M
Age = 42.2 years; MEducation = 12.7) patients clinically referred for neuropsychological assessment. Trials 2 and Retention of the TOMM, the Word Choice Test, and three validity composites were used as criterion PVTs. Classification accuracy varied systematically as a function of criterion PVT. TOMM-1 ≤ 43 emerged as the optimal cutoff, resulting in a wide range of sensitivity (.47-1.00), with perfect overall specificity. Failing the TOMM-1 was unrelated to age, education or gender, but was associated with elevated self-reported depression. Results support the utility of TOMM-1 as an independent, free-standing, single-trial PVT. Consistent with previous reports, the choice of criterion measure influences parameter estimates of the PVT being calibrated. The methodological implications of modality specificity to PVT research and clinical/forensic practice should be considered when evaluating cutoffs or interpreting scores in the failing range.- Published
- 2021
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7. A comparison of the MMPI-2-RF and PAI overreporting indicators in a civil forensic sample with emphasis on the Response Bias Scale (RBS) and the Cognitive Bias Scale (CBS).
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Tylicki JL, Rai JK, Arends P, Gervais RO, and Ben-Porath YS
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- Adult, Bias, Cognitive Dysfunction psychology, Female, Humans, Logistic Models, MMPI, Male, Malingering psychology, Middle Aged, Neuropsychological Tests, Reproducibility of Results, Sensitivity and Specificity, Cognitive Dysfunction diagnosis, Disability Evaluation, Malingering diagnosis, Personality Inventory
- Abstract
The Cognitive Bias Scale (CBS; Gaasedelen, Whiteside, Altmaier, Welch, & Basso, 2019) was developed as a Personality Assessment Inventory (PAI) indicator of poor performance on Performance Validity Tests (PVTs) in a neuropsychological context. The current study aimed to investigate the effectiveness of the CBS in a forensic disability sample through a series of analyses by comparing it to other PAI validity scales and the Minnesota Multiphasic Personality Inventory (MMPI)-2-RF overreporting scales with an emphasis on the Response Bias Scale (RBS), which guided the development of the CBS. The participants in this study were drawn from an archival dataset containing 588 consecutive civil disability claimants. Findings showed the RBS and the CBS yielded similar patterns of negative correlations to PVTs, with RBS effect sizes being somewhat larger in most comparisons. Results of ANOVAs showed that the RBS produced the largest effect sizes in distinguishing between incentive only versus probable/definite malingered neurocognitive dysfunction (MND) groups, followed by the CBS. Estimates of sensitivity and specificity were comparable between the RBS and CBS at liberal cut scores, but the RBS was more specific to detecting Probable/Definite MND at more conservative cutoffs. Hierarchical logistic regression analyses showed that RBS accounted for 6% variance over CBS in the probable/definite MND classification, whereas the CBS accounted for 2% variance beyond the RBS. Overall, the results of this study support the utility of the CBS as the most effective PAI validity scale for detecting MND in a civil disability sample, and the RBS generally outperformed the CBS to some degree in all analyses. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
- Published
- 2021
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8. Therapeutic assessment and the art of feedback: A model for integrating evidence-based assessment and therapy techniques in neurological rehabilitation.
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Waldron-Perrine B, Rai JK, and Chao D
- Subjects
- Feedback, Humans, Neuropsychological Tests, Neurological Rehabilitation
- Abstract
Background: Therapeutic assessment involves the integration of evidence-based approaches and humanistic principles, and there is empirical support for the use of this approach in the context of neuropsychological assessment broadly., Objective: We propose that therapeutic assessment (TA) and collaborative therapeutic neuropsychological assessment (CTNA) principles are appropriate and effective for application within a neurological rehabilitation population specifically., Methods: We review TA and CTNA principles and propose a model for their application to a neurological rehabilitation population, with an emphasis on describing the strengths of the collaborative approach, guidelines and principles for maximizing the efficacy of feedback, and transitioning the patient into psychotherapy services to further address their personal goals. A case example of a neurologically injured individual engaged in CTNA and subsequent intervention is shared to highlight the principles discussed., Results and Conclusion: The proposed model and case study demonstrate the clinical utility of TA and CTNA principles with a neurological rehabilitation population.
- Published
- 2021
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9. Mites (Acari) as a Relevant Tool in Trace Evidence and Postmortem Analyses of Buried Corpses.
- Author
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Rai JK, Amendt J, Bernhardt V, Pasquerault T, Lindström A, and Perotti MA
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- Animals, Cadaver, Diptera, Germany, Humans, Postmortem Changes, Soil, Sweden, Burial, Forensic Entomology methods, Mites
- Abstract
This report interprets the presence of mite species in three clandestine graves in Europe, evaluating their potential use as trace evidence or markers. Grave 1 (Sweden): Two mite species Rhizoglyphus robini Claparède, 1869 and Parasitus loricatus (Wankel, 1861) were recovered from the surface of a body buried in a shallow grave in an area surrounded by trees, in close vicinity to house gardens. Grave 2 (Germany): Phoretic deutonymphs of Gamasodes spiniger (Trägårdh, 1910) were attached to an adult fly (Diptera: Sphaeroceridae) found within a shallow grave containing two human bodies covered in soil and dung. Grave 3 (France): P. loricatus were recovered from the soil around a body buried in a deep grave (80 cm under). In graves 1 and 3 both corpses were undergoing advanced decay and skeletization, the locations match with the subterranean habit of P. loricatus, highlighting the value of this species as a marker of graves or burials in soil and during late decomposition. R. robini is a soil mite that feeds on decayed roots and bulbs; this mite species confirms the location of the corpse within top soil, agreeing with a more specific type of superficial burial, a shallow grave. In case 2, the presence of both coprophiles, the mite G. spiniger and the carrier fly confirm association of remains with dung or animal feces. The three mite species are reported for the first time in human graves. There are no previous records of R. robini from Sweden., (© 2020 The Authors. Journal of Forensic Sciences published by Wiley Periodicals LLC on behalf of American Academy of Forensic Sciences.)
- Published
- 2020
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10. Scalp electroencephalography (sEEG) based advanced prediction of epileptic seizure time and identification of epileptogenic region.
- Author
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Sharma A, Rai JK, and Tewari RP
- Abstract
Objectives Epilepsy is characterized by uncontrollable seizure during which consciousness of patient is disturbed. Prediction of the seizure in advance will increase the remedial possibilities for the patients suffering from epilepsy. An automated system for seizure prediction is important for seizure enactment, prevention of sudden unexpected deaths and to avoid seizure related injuries. Methods This paper proposes the prediction of an upcoming seizure by analyzing the 23 channel non-stationary EEG signal. EEG signal is divided into smaller segments to change it into quasi-stationary data using an overlapping moving window. Brain region is marked into four regions namely left hemisphere, right hemisphere, central region and temporal region to identify the epileptogenic region. The epileptogenic region shows significant variations during pre-ictal state in comparison to the other regions. So, seizure prediction is carried out by analyzing EEG signals from this region. Seizure prediction is proposed using features extracted from both time and frequency domain. Relative entropy and relative energy are extracted from wavelet transform and Pearson correlation coefficient is obtained from time domain EEG signal. Extracted features have been smoothened using moving average filter. First order derivative of relative features have been used to normalize the intervariability before deciding the threshold for marking the prediction of seizure. Results Isolated seizures where pre-ictal duration of more than 1 h is reported has been detected with an accuracy of 92.18% with precursory warning 18 min in advance and seizure confirmation 12 min in advance. An overall accuracy of 83.33% with false positive alarm rate of 0.01/h has been obtained for all seizure cases with average prediction time of 9.9 min.
- Published
- 2020
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11. Utility of critical items within the Recognition Memory Test and Word Choice Test.
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Erdodi LA, Tyson BT, Abeare CA, Zuccato BG, Rai JK, Seke KR, Sagar S, and Roth RM
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- Adult, Aged, Analysis of Variance, Female, Humans, Male, Malingering, Middle Aged, Psychometrics, Reproducibility of Results, Sensitivity and Specificity, Signal Detection, Psychological, Choice Behavior physiology, Memory Disorders diagnosis, Memory Disorders physiopathology, Neuropsychological Tests, Recognition, Psychology physiology
- Abstract
This study was designed to examine the clinical utility of critical items within the Recognition Memory Test (RMT) and the Word Choice Test (WCT). Archival data were collected from a mixed clinical sample of 202 patients clinically referred for neuropsychological testing (54.5% male; mean age = 45.3 years; mean level of education = 13.9 years). The credibility of a given response set was psychometrically defined using three separate composite measures, each of which was based on multiple independent performance validity indicators. Critical items improved the classification accuracy of both tests. They increased sensitivity by correctly identifying an additional 2-17% of the invalid response sets that passed the traditional cutoffs based on total score. They also increased specificity by providing additional evidence of noncredible performance in response sets that failed the total score cutoff. The combination of failing the traditional cutoff, but passing critical items was associated with increased risk of misclassifying the response set as invalid. Critical item analysis enhances the diagnostic power of both the RMT and WCT. Given that critical items require no additional test material or administration time, but help reduce both false positive and false negative errors, they represent a versatile, valuable, and time- and cost-effective supplement to performance validity assessment.
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- 2018
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12. Epileptic seizure anticipation and localisation of epileptogenic region using EEG signals.
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Sharma A, Rai JK, and Tewari RP
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- Brain physiopathology, Epilepsy physiopathology, Humans, Neural Networks, Computer, Reproducibility of Results, Seizures physiopathology, Algorithms, Electroencephalography methods, Epilepsy diagnosis, Machine Learning, Seizures diagnosis
- Abstract
Electric activity of brain gets disturbed prior to epileptic seizure onset. Early prediction of an upcoming seizure can help to increase effectiveness of antiepileptic drugs. The scalp electroencephalogram signals contain information about the dynamics of brain and have been used to predict an upcoming seizure and localise its zone. The objective of this paper is to localise the epileptogenic region and predict an upcoming seizure at the earliest. To localise epileptogenic region, Electroencephalogram signals are categorised into four regions of brain (Frontal, Temporal, Parietal and Central). For each signal seventy-two (72) parameters in frequency domain have been extracted by using ten minute non overlapping window. Four prominent ratio parameters, γ1/γ5, γ3/γ1, θ/γ2 and γ4/θ have been identified as best parameters based on relative fisher score. Zone 2 shows the highest change in all the parameters as compared to the other zones. So, temporal region is identified as the epileptogenic region in this work. For prediction of the epileptic seizure machine learning algorithm artificial neural network (ANN) is proposed. The proposed machine learning algorithm has an accuracy of 92.3%, sensitivity of 100% and specificity of 83.3%.
- Published
- 2018
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13. Wisconsin Card Sorting Test embedded validity indicators developed for adults can be extended to children.
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Lichtenstein JD, Erdodi LA, Rai JK, Mazur-Mosiewicz A, and Flaro L
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- Adolescent, Child, Female, Humans, Male, Reproducibility of Results, Neuropsychological Tests, Wisconsin Card Sorting Test statistics & numerical data
- Abstract
Past studies have examined the ability of the Wisconsin Card Sorting Test (WCST) to discriminate valid from invalid performance in adults using both individual embedded validity indicators (EVIs) and multivariate approaches. This study is designed to investigate whether the two most stable of these indicators-failures to maintain set (FMS) and the logistical regression equation S-B
LRE -can be extended to pediatric populations. The classification accuracy for FMS and S-BLRE was examined in a mixed clinical sample of 226 children aged 7 to 17 years (64.6% male, MAge = 13.6 years) against a combination of established performance validity tests (PVTs). The results show that at adult cutoffs, FMS and S-BLRE produce an unacceptably high failure rate (33.2% and 45.6%) and low specificity (.55-.72), but an upward adjustment in cutoffs significantly improves classification accuracy. Defining Pass as <2 and Fail as ≥4 on FMS results in consistently good specificity (.89-.92) but low and variable sensitivity (.00-.33). Similarly, cutting the S-BLRE distribution at 3.68 produces good specificity (.90-.92) but variable sensitivity (.06-.38). Passing or failing FMS or S-BLRE is unrelated to age, gender and IQ. The data from this study suggest that in a pediatric sample, adjusted cutoffs on the FMS and S-BLRE ensure good specificity, but with low or variable sensitivity. Thus, they should not be used in isolation to determine the credibility of a response set. At the same time, they can make valuable contributions to pediatric neuropsychology by providing empirically-supported, expedient and cost-effective indicators to enhance performance validity assessment.- Published
- 2018
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14. Embedded validity indicators in Conners' CPT-II: Do adult cutoffs work the same way in children?
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Erdodi LA, Lichtenstein JD, Rai JK, and Flaro L
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- Adolescent, Brain Injuries, Traumatic complications, Child, Cognition Disorders etiology, Cognition Disorders psychology, Executive Function physiology, Female, Humans, Male, Malingering psychology, Memory physiology, Neuropsychological Tests, Reproducibility of Results, Sensitivity and Specificity, Brain Injuries, Traumatic psychology, Cognition physiology, Cognition Disorders diagnosis, Intelligence physiology, Malingering diagnosis
- Abstract
In previous research, several subscales of Conners' CPT-II were found to be useful as performance validity tests (PVTs) when administered to adults with traumatic brain injury (TBI). Furthermore, invalid response sets were associated with inflated scores on several CPT-II scales. The present study proposed to investigate whether these findings would replicate in a pediatric sample. The analyses were based on archival data from 15 children with TBI. The Omissions, Hit RT, Perseverations, and Hit RT BC scales proved effective at differentiating valid and invalid response sets. However, Commission errors were unrelated to scores on PVTs. A composite measure based on these four scores was a superior and more stable validity indicator than individual scales. Two or more T-scores >65 on any of these scales resulted in acceptable overall specificity (.86-1.00) and variable sensitivity (.00-1.00). Scores on CPT-II scales were generally higher among those who failed the reference PVTs. Results suggest that embedded CPT-II validity indices developed in adult TBI samples function similarly in children with TBI, with some notable exceptions. Although the use of adult PVT cutoffs in pediatric assessment is a common practice, and broadly supported by the present findings, there remains a clear need for the independent empirical validation of adult PVTs in children.
- Published
- 2017
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15. [Formula: see text]Parent rating of executive function in fetal alcohol spectrum disorder: A review of the literature and new data on Aboriginal Canadian children.
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Rai JK, Abecassis M, Casey JE, Flaro L, Erdodi LA, and Roth RM
- Subjects
- Adolescent, Canada, Child, Child, Preschool, Female, Humans, Male, Neuropsychological Tests, Parents, Executive Function physiology, Fetal Alcohol Spectrum Disorders psychology
- Abstract
Aboriginal children in Canada are at high risk of fetal alcohol spectrum disorder (FASD) but there is little research on the cognitive impact of prenatal alcohol exposure (PAE) in this population. This paper reviews the literature on parent report of executive functioning in children with FASD that used the Behavior Rating Inventory of Executive Function (BRIEF). New data on the BRIEF is then reported in a sample of 52 Aboriginal Canadian children with FASD for whom a primary caregiver completed the BRIEF. The children also completed a battery of neuropsychological tests. The results reveal mean scores in the impaired range for all three BRIEF index scores and seven of the eight scales, with the greatest difficulties found on the Working Memory, Inhibit and Shift scales. The majority of the children were reported as impaired on the index scores and scales, with Working Memory being most commonly impaired scale. On the performance-based tests, Trails B and Letter Fluency are most often reported as impaired, though the prevalence of impairment is greater for parent ratings than test performance. No gender difference is noted for the parent report, but the boys had slightly slower intellectual functioning and were more perseverative than the girls on testing. The presence of psychiatric comorbidity is unrelated to either BRIEF or test scores. These findings are generally consistent with prior studies indicating that parents observe considerable executive dysfunction in children with FASD, and that children with FASD may have more difficulty with executive functions in everyday life than is detected by laboratory-based tests alone.
- Published
- 2017
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16. A single error is one too many: Examining alternative cutoffs on Trial 2 of the TOMM.
- Author
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Erdodi LA and Rai JK
- Subjects
- Adult, Brain Injuries, Traumatic psychology, Female, Humans, Male, Malingering psychology, Middle Aged, Neuropsychological Tests, Sensitivity and Specificity, Brain Injuries, Traumatic diagnosis, Malingering diagnosis, Memory physiology
- Abstract
Objective: This study investigated the potential of alternative, more liberal cutoffs on Trial 2 of the Test of Memory Malingering (TOMM) to improve classification accuracy relative to the standard cutoffs (≤44)., Method: The sample consisted of 152 patients (49.3% male) with psychiatric conditions (PSY) and traumatic brain injury (TBI) referred for neuropsychological assessment in a medico-legal setting (M
Age = 44.4, MEducation = 11.9 years). Classification accuracy for various TOMM Trial 2 cutoffs was computed against three criterion measures., Results: Patients with TBI failed TOMM Trial 2 cutoffs at higher rates than patients with PSY. Trial 2 ≤49 achieved acceptable combinations of sensitivity (0.38-0.67) and specificity (0.89-0.96) in all but one comparison group. Trial 2 ≤48 improved specificity (0.94-0.98) with minimal loss in sensitivity. The standard cutoff (≤44) disproportionally traded sensitivity (0.15-0.50) for specificity (0.96-1.00)., Conclusions: One error on TOMM Trial 2 constitutes sufficient evidence to question the credibility of a response set. However, the confidence in classifying a score as invalid continues to increase with each additional error. Even at the most liberal conceivable cutoff (≤49), the TOMM detected only about half of the patients who failed other criterion measures. Therefore, it should never be used in isolation to determine performance validity.- Published
- 2017
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17. Hypercalcemia with extraosseous MDP uptake in a bone scan as initial presentation in a case of cutaneous T-cell lymphoma.
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Palaniswamy SS, Padma S, Harish V, and Rai JK
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- Adult, Diagnosis, Differential, Female, Humans, Prognosis, Radionuclide Imaging, Radiopharmaceuticals pharmacokinetics, Tissue Distribution, Bone and Bones diagnostic imaging, Hypercalcemia diagnostic imaging, Hypercalcemia etiology, Lymphoma, T-Cell, Cutaneous complications, Lymphoma, T-Cell, Cutaneous diagnostic imaging, Technetium Tc 99m Medronate pharmacokinetics
- Abstract
A middle-aged lady presented with headache, vomiting of sudden-onset with intermittent evening rise of temperature. She also had slurring of speech with no loss of consciousness or altered sensorium. The patient was under evaluation for hypercalcemia. A whole body bone scan was done to look for causes of hypercalcemia and the scan showed extraosseous 99m Tc MDP (Technetium Methylene Di Phosphonate) uptake. One of the causes of extraosseous MDP uptake is cutaneous T-cell lymphoma (CTCL). On close interrogation the patient gave a history of hypopigmented dermal patches for more than 2 years duration. The coexisting dermal patches raised suspicion of CTCL. Skin biopsy confirmed CTCL. The patient was referred to oncology and was planned for six cycles of chemotherapy.
- Published
- 2011
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18. A rare cause of spontaneous intra-abdominal haemorrhage due to coeliac artery stenosis.
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Rai JK, Shankar A, and Brookes J
- Abstract
Coeliac artery stenosis is associated with the formation of collateral vessels from the superior mesenteric artery. High pressure within collateral vessels can lead to the formation of visceral artery aneurysms. Haemorrhage from such aneurysms can be catastrophic if they are not identified and managed promptly. We describe successful arterial embolisation of a pseudoaneurysm arising from a branch of the gastroduodenal artery secondary to coeliac artery stenosis. To the best of our knowledge this is thefirst such reported case in the literature.
- Published
- 2010
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19. Staring secondaries, where is the primary?
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Sundaram PS, Padma S, Rai JK, and Harish V
- Abstract
An asymptomatic issueless young staff nurse underwent pre-employment health screening and USG abdomen showed multiple hypodense lesions in liver. Further screening with whole body positron emission tomography-computed tomography (PET-CT) scan showed significantly FDG avid mass involving most of the right lobe of liver with multiple large FDG avid lymph nodal metastases. Unsuspected focal abnormal, FDG avid, hyperdense mural nodule was seen in uterus, which is the site of primary.
- Published
- 2010
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20. Cosmetic surgery in the NHS: Applying local and national guidelines.
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Breuning EE, Oikonomou D, Singh P, Rai JK, and Mendonca DA
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- Body Mass Index, Chi-Square Distribution, Female, Humans, Male, Postoperative Complications epidemiology, Retrospective Studies, Smoking epidemiology, United Kingdom epidemiology, Abdomen surgery, Breast Diseases surgery, Guideline Adherence, Mammaplasty standards, Practice Guidelines as Topic, Practice Patterns, Physicians' statistics & numerical data, State Medicine, Surgery, Plastic standards
- Abstract
There is no worldwide consensus, as to how healthcare should be funded, in a modern society. Limited resources in the UK, have led to restrictions on cosmetic surgery in the NHS. Guidelines governing access to cosmetic surgery have been formulated. A retrospective audit has been undertaken, to assess adherence to local and national guidelines, in an NHS trust. Ninety-nine casenotes were reviewed over 1 year. Data on complications were collected. Compliance to local guidelines was 44% and to national guidelines was 22%. Complication rate was 23% in guideline compliant patients and 55% in non-compliant patients (P<0.005). Guidelines are difficult to follow in practice. Total adherence to guidelines would reduce waiting lists and complications, but some needy patients could be denied treatment. In practice, rigid adherence to guidelines is not possible., (Copyright 2009 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2010
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21. Trapeziectomy with a capsular interposition flap.
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Rai JK, Singh P, Mendonca D, and Porter M
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- Humans, Osteoarthritis surgery, Surgical Flaps, Trapezium Bone surgery
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- 2009
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22. Management of a neglected giant squamous cell carcinoma of the scalp.
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Rai JK, Singh P, Mendonca DA, and Porter JM
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- Aged, Biopsy, Carcinoma, Squamous Cell surgery, Head and Neck Neoplasms surgery, Humans, Male, Skin Neoplasms surgery, Carcinoma, Squamous Cell pathology, Head and Neck Neoplasms pathology, Scalp pathology, Skin Neoplasms pathology
- Published
- 2009
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23. Micro determination of ascorbic acid using methyl viologen.
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Janghel EK, Gupta VK, Rai MK, and Rai JK
- Abstract
A new simple and sensitive analytical spectrophotometric method is developed for the determination of ascorbic acid reduces methyl viologen to form a stable blue coloured free radical ion. This method has a sensitivity and lower limit detection of 0.1mugml(-1) of ascorbic acid (0.1ppm) which is comparable to the flow injection analysis reported earlier. Beer's law is obeyed over the concentration range of 1.0-10mugml(-1) of ascorbic acid per 10ml of the final solution (0.1-1.0mugml(-1)) at 600nm. The molar absorptivity and Sandell's sensitivity were found to be 1.5x10(5)+/-100lmol(-1)cm(-1) and 0.001mugcm(-2), respectively. The method has been applied to the determination of ascorbic acid in food, pharmaceuticals and biological samples.
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- 2007
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24. Post-transplant lymphoproliferative disease in liver transplantation.
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Dhillon MS, Rai JK, Gunson BK, Olliff S, and Olliff J
- Subjects
- Adult, Aged, Female, Humans, Immunosuppressive Agents therapeutic use, Liver diagnostic imaging, Liver pathology, Liver Cirrhosis, Biliary complications, Liver Cirrhosis, Biliary diagnostic imaging, Liver Transplantation diagnostic imaging, Liver Transplantation immunology, Lymphoproliferative Disorders diagnostic imaging, Lymphoproliferative Disorders immunology, Male, Middle Aged, Practice Guidelines as Topic, Radiography, Retrospective Studies, Time Factors, Treatment Outcome, Liver Transplantation adverse effects, Lymphoproliferative Disorders etiology
- Abstract
Post-transplant lymphoproliferative disease (PTLD) is a well recognized complication of solid organ transplantation and therapeutic immunosuppression, first reported in 1968. PTLD incorporates a spectrum of abnormalities ranging from a benign infectious mononucleosis-like illness to non-Hodgkin's lymphoma with nodal and extranodal site involvement. The first liver transplant was performed at our institution in January 1982. This retrospective study examined the incidence of PTLD, reason for the original transplants, presenting symptoms, radiological findings, immunosuppression regimens and outcomes of these patients. From a total of 2005 adult liver transplants, 23 patients (1.1%) were identified with PTLD. The average age of these patients at the time of transplant was 46.5 years, with a ratio of female-to-male of 14:9. Indication for transplant ranged from primary biliary cirrhosis (eight patients) to epitheloid haemangioendothelioma (one patient). The average time interval between transplant and diagnosis of PTLD was 50 months. Imaging abnormalities identified included generalized lymphadenopathy, liver and portal masses, splenic enlargement, bowel, eye, cerebral and neck involvement; and in two patients, no radiological abnormality. The most common histological findings ranged from B-cell non-Hodgkin's lymphoma (five patients) to early PTLD in one patient. Our rate of PTLD is lower compared with published literature and demonstrates a much longer time interval from transplant to occurrence of PTLD than previously appreciated. This could be secondary to a low immunosuppression therapy followed at our institution. From a few months to several years after liver transplantation, the radiologist needs to be alert to the possibility of PTLD and thorough imaging is required to detect the wide variety of potential presentations.
- Published
- 2007
- Full Text
- View/download PDF
25. TLC-spectrophometric separation and trace determination of monocrotophos and dichlorvos in enviromental and biological samples.
- Author
-
Janghel EK, Rai JK, Khan S, Rai MK, and Gupta VK
- Subjects
- Chemistry Techniques, Analytical methods, Hydrogen-Ion Concentration, Indicators and Reagents pharmacology, Pesticide Residues analysis, Reproducibility of Results, Solvents analysis, Temperature, Time Factors, Water Pollutants, Chemical analysis, Chromatography, Thin Layer methods, Dichlorvos analysis, Environmental Monitoring methods, Monocrotophos analysis, Spectrophotometry methods
- Abstract
Organophosphorus insecticides, monocrotophos and dichlrovos are increasingly being used in agriculture to control insects on a wide range of crops. Their ready access has resulted in misuse in many instances of homicidal and suicidal poisoning cases. This paper describes about a chromogenic spray reagent for the detection/determination of monocrophos and dichlrovos in environmental and biological samples by TLC and spectrophotometric method. Monocrotophos and dichlorvos on alkaline hydrolysis yield N-methyl acetoacetamide and dichlroacetaldehyde respectively, which in turn react with diazotized p-amino acetophenone to give red-violet and red coloured compounds. Other organophosphorus insecticides do not give this reaction. Moreover, organochlorine and synthetic pyrethroid insecticides and constituents of viscera (amino acids, peptides, proteins etc), which are generally coextracted with the insecticides, do not interfere. However, phenolic compounds and hydrolysed product of carbamate insecticides may interfere and differentiate from monocrotophos and dichlrovos by Rf values. The lower limit of detection is 0.2 mg for monocrotophos and 0.1 mg for dichlorovos. The absorption maxima of the reddish-violet and red colour formed by monocrotophos and dichlrovos, are measured at 560 nm and 540 nm respectively. Beer's Law is obeyed over the concentration range of 1.2 to 6.8 mg and 6.2 to 35 mg in the final solution volume of 25 mL. The molar absorptivity and Sandell's sensitivity of monocrotophos and dichlrovos were found to be 7.1 x 10(5) (+100) 1 mole(-1) cm(-1) and 0.008 mg cm(-2), 1.2 x 10(5) 1 mole(-1) cm(-1) and 0.003 mg cm(-2) respectively. The standard deviation and relative standard deviation were found be +/- 0.005 and 2.05% +/- 0.007 and 2.02% respectively. The developed method has been successfully applied to the detection and determination of monocrotophos and dichlrovos in environmental and biological samples.
- Published
- 2007
26. [Profile of a nurse. Ms Jiwan Kala Rai of Nepal who is studying ICU nursing in Japan].
- Author
-
Rai JK
- Subjects
- Japan, Nepal ethnology, Critical Care, Specialties, Nursing
- Published
- 1981
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