Search

Objective: To determine the association of ABO blood groups with clinicopathological factors among gastric cancer patients. Study type, settings & duration: This cross-sectional study conducted at the Department of Medical Oncology, Jinnah Postgraduate Medical Centre, Karachi from January 2019 to March 2020. Methodology: All the patients with confirmed diagnosis of gastric cancer of age from 15-90 years and of either gender were included in the study on the basis of convenience sampling. Type of ABO blood group was identified from laboratory and from blood transfusion section of the hospital. The socio-demographic and clinicopathological data was also recorded on pre-designed proforma. SPSS version 23 was used to analyse data. Results: The mean age of the study sample was 48.31±12.36 years (range: 19-85 years). Out of 144 gastric cancer patients, 51 patients had A type 35.4%, 45 had type B 31.3%, 40 had type O 27.8% and 8 had AB type of blood (5.6%). There was statistically significant association between ABO blood type grade and stage of tumour (p =0.013) and (p =0.05) respectively. Conclusion: Blood group A is the most common blood group found in patients with gastric tumour. Pathologically well differentiated tumour grade is most common grade seen in blood group O, whereas tumour stage III is observed in blood group type B. [ABSTRACT FROM AUTHOR]