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34. Epidemiology and Survival of Kaposi’s Sarcoma by Race in the United States: A Surveillance, Epidemiology, and End Results Database Analysis

Author

Ragi,Sara D, Moseley,Isabelle, Ouellette,Samantha, Rao,Babar, Ragi,Sara D, Moseley,Isabelle, Ouellette,Samantha, and Rao,Babar

Abstract

Sara D Ragi,1 Isabelle Moseley,1 Samantha Ouellette,2 Babar Rao2 1The Warren Alpert Medical School of Brown University, Providence, RI, USA; 2Department of Dermatology, Robert Wood Johnson Medical School, New Brunswick, NJ, USACorrespondence: Sara D Ragi, Email sara_ragi@brown.eduAbstract: The introduction of highly active antiretroviral treatment (HAART) for acquired immunodeficiency syndrome (AIDS) has led to a significant decrease in the incidence of Kaposi’s sarcoma (KS) in recent years. However, a concomitant increase in racial disparities in KS has arisen. Here, we analyze data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) Program for epidemiology and survival of Kaposi’s sarcoma by race. The highest incidence was observed among Black patients (incidence rate (IR), 1.189; 95% confidence interval (CI), 1.092– 1.189), followed by White patients (IR, 0.486; 95% CI, 0.473– 0.498). Relative survival at 1, 3, and 5 years differed significantly by race, with White patients having the highest survival rates (84.26%, 77.79%, and 74.79% at 1, 3, and 5 years respectively) and Black patients demonstrating the lowest (71.50%, 61.37%, and 57.38%), with intermediate survival rates in Asians/Pacific Islanders (AAPI) (80.62%, 71.19%, and 67.28%) and American Indians/Alaska Natives (AIAN) (80.56%, 61.45%, and 61.45%). We conclude that there are significant racial disparities in the incidence, epidemiology, and survival of KS.Keywords: Kaposi’s sarcoma, racial disparities, race, cancer, soft tissue sarcoma, surveillance, epidemiology, end results program, epidemiology

Published
2022

38. Long-term vitamin A supplementation in a preclinical mouse model forRhoD190N-associated retinitis pigmentosa

Author

Cui, Xuan, primary, Kim, Hye Jin, additional, Cheng, Chia-Hua, additional, Jenny, Laura A, additional, Lima de Carvalho, Jose Ronaldo, additional, Chang, Ya-Ju, additional, Kong, Yang, additional, Hsu, Chun-Wei, additional, Huang, I-Wen, additional, Ragi, Sara D, additional, Lin, Chyuan-Sheng, additional, Li, Xiaorong, additional, Sparrow, Janet R, additional, and Tsang, Stephen H, additional

Published
2022
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39. Tinea pedis in underrepresented groups: All of Us database analysis.

Author

Moseley, Isabelle, Ragi, Sara D., Ouellette, Samantha, and Rao, Babar

Subjects
*ELECTRONIC health records, *BLACK people, *SECONDARY education, *AGE groups, *DATA release
Abstract

Background: Tinea pedis is the most common form of dermatophytosis resulting in interdigital infections. All of Us (AoU) is a National Institute of Health initiative with an emphasis on patient populations traditionally underrepresented in biomedical research. Objectives: Our objective was to evaluate the burden of tinea pedis in underrepresented groups in the United States, utilising the novel AoU research program. Methods: We analysed AoU Registered Tier dataset version 5, which includes data collected between 30 May, 2017, and 1 April, 2021. We conducted a cross‐sectional analysis linking survey and electronic health record (EHR) data to estimate the prevalence of tinea pedis in underrepresented groups. Results: All of Us data release includes 329,038 participants. Of these, 251,597 (76.5%) had electronic health record data and 6932 had tinea pedis (overall prevalence, 2.76%; 95% CI, 2.69–2.82). Multivariate analyses revealed that compared with White participants, Black and Hispanic participants had a higher adjusted odds of tinea pedis (OR, 1.29; 95% CI, 1.20–1.38 and OR, 1.38; 95% CI, 1.28–1.48, respectively). Higher adjusted odds of tinea pedis were observed in underrepresented groups defined by: age > =75 years (OR, 1.45; 95% CI, 1.33–1.57), LGBTQ status (OR, 1.17; 95% CI, 1.09–1.27), less than a high school education (OR, 1.22; 95% CI, 1.11–1.34), income <$35,000 (OR, 1.09; 95% CI, 1.02–1.16) and physical disability (OR, 1.56; 95% CI, 1.08–1.24). Conclusions: Our findings are consistent with overall age, and gender‐specific prevalence estimates from prior epidemiologic studies, validating the scientific consistency of the new AoU database. Additionally, there may be an increased burden of tinea pedis among Black and Hispanic individuals. [ABSTRACT FROM AUTHOR]

Published
2023
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42. CNGB1 ‐related rod‐cone dystrophy: A mutation review and update

Author

Nassisi, Marco, primary, Smirnov, Vasily M., additional, Solis Hernandez, Cyntia, additional, Mohand‐Saïd, Saddek, additional, Condroyer, Christel, additional, Antonio, Aline, additional, Kühlewein, Laura, additional, Kempf, Melanie, additional, Kohl, Susanne, additional, Wissinger, Bernd, additional, Nasser, Fadi, additional, Ragi, Sara D., additional, Wang, Nan‐Kai, additional, Sparrow, Janet R., additional, Greenstein, Vivienne C., additional, Michalakis, Stylianos, additional, Mahroo, Omar A., additional, Ba‐Abbad, Rola, additional, Michaelides, Michel, additional, Webster, Andrew R., additional, Degli Esposti, Simona, additional, Saffren, Brooke, additional, Capasso, Jenina, additional, Levin, Alex, additional, Hauswirth, William W., additional, Dhaenens, Claire‐Marie, additional, Defoort‐Dhellemmes, Sabine, additional, Tsang, Stephen H., additional, Zrenner, Eberhart, additional, Sahel, Jose‐Alain, additional, Petersen‐Jones, Simon M., additional, Zeitz, Christina, additional, and Audo, Isabelle, additional

Published
2021
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47. Epidemiology and Survival of Eccrine Porocarcinoma by Sex in the United States: A Surveillance, Epidemiology, and End Results Database Analysis.

Author

Ragi, Sara D., Moseley, Isabelle, Ouellette, Samantha, and Rao, Babar

Subjects
*MASS surveillance, *ADNEXAL diseases, *EPIDEMIOLOGY
Abstract

Namely, EPC may be less likely to be detected at earlier stages in men because a greater proportion of cases in men were located at distant sites (indicating that the tumor has spread to nonadjacent tissues), whereas EPC was most likely to be localized in women. Eccrine porocarcinoma (EPC) is a rare, multifocal tumor arising from the intraepidermal ducts of sweat glands. Women experienced a significantly greater proportion of EPCs of the trunk, and lower limb/hip, whereas men had a greater percentage of EPCs of the head/neck, and upper limb/shoulder. [Extracted from the article]

Published
2023
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49. Specialties with Few Underrepresented Applicants Lack Diversity Information on Residency Websites.

Author

TRAN, MEGAN M., HONG, JESSICA, HUANG, LAWRENCE, CHANG, KENNY, LEE, ADRIAN, RAGI, SARA D., and KAWAOKA, JOHN

Abstract

INTRODUCTION: With the advent of virtual interviews and the increasing accessibility of internet resources, students increasingly rely on program websites for residency application decisions. In this cross-sectional study, we evaluated the presence of diversity or inclusion information in the least diverse US specialties' residency program websites, including dermatology, orthopedic surgery, otolaryngology, plastic surgery, and urology residency programs. METHODS: Two authors independently reviewed each Accreditation Council for Graduate Medical Education-accredited non-military US residency program website and ranked the websites' diversity and inclusion information using six pre-determined criteria based on previous studies in the literature. RESULTS: This study reveals that more than half of residency programs of each specialty met zero of the diversity and inclusion information criteria. CONCLUSIONS: Residency program websites in the least diverse specialties are lacking important information for prospective applicants that may help signal programs' commitment to inclusivity and attract a diverse candidate pool. [ABSTRACT FROM AUTHOR]

Published
2023

50. A Pearl for Pretibial and Forearm Repair Following Mohs Micrographic Surgery.

Author

Otto TS, Ragi SD, John AM, and Bhatti H

Subjects
Humans, Tissue Adhesives, Leg surgery, Male, Female, Mohs Surgery adverse effects, Mohs Surgery methods, Forearm surgery, Suture Techniques, Skin Neoplasms surgery, Wound Healing
Abstract

Wound repair of the pretibial and forearm regions presents a challenge during dermatologic surgery as these areas are under significant tension and exhibit increased skin fragility. Various methodologies have been proposed for the closure and repair of such wounds, however, the use of the bilayered suture technique may be simpler and more effective than other techniques such as the pinch stitch, pully stitch, slip-knot stitch, pulley set-back dermal suture, horizontal mattress suture, pully stitch, and tandem pulley stitch. Our objective was to describe a novel method for the repair of pretibial and forearm wounds following Mohs micrographic surgery utilizing bilayered closure followed by tissue adhesive application.&nbsp; J Drugs Dermatol. 2024;23(5):380.&nbsp; &nbsp; &nbsp;doi:10.36849/JDD.7139 &nbsp.

Published
2024
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