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8. Projective-geometric aspects of homogeneous third-order Hamiltonian operators

Author

Ferapontov, Eugene V., Pavlov, Maxim V., and Vitolo, Raffaele F.

Subjects
Nonlinear Sciences - Exactly Solvable and Integrable Systems
Abstract

We investigate homogeneous third-order Hamiltonian operators of differential-geometric type. Based on the correspondence with quadratic line complexes, a complete list of such operators for two and three components is obtained. more...

Published
2014
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9. A first-of-its-kind multi-model convection permitting ensemble for investigating convective phenomena over Europe and the Mediterranean

Author

Coppola, Erika, Sobolowski, Stefan, Pichelli, E., Raffaele, F., Ahrens, B., Anders, I., Ban, N., Bastin, S., Belda, M., Belusic, D., Caldas-Alvarez, A., Cardoso, R. M., Davolio, S., Dobler, A., Fernandez, J., Fita, L., Fumiere, Q., Giorgi, F., Goergen, K., Güttler, I., Halenka, T., Heinzeller, D., Hodnebrog, Ø., Jacob, D., Kartsios, S., Katragkou, E., Kendon, E., Khodayar, S., Kunstmann, H., Knist, S., Lavín-Gullón, A., Lind, P., Lorenz, T., Maraun, D., Marelle, L., van Meijgaard, E., Milovac, J., Myhre, G., Panitz, H.-J., Piazza, M., Raffa, M., Raub, T., Rockel, B., Schär, C., Sieck, K., Soares, P. M. M., Somot, S., Srnec, L., Stocchi, P., Tölle, M. H., Truhetz, H., Vautard, R., de Vries, H., and Warrach-Sagi, K. more...

Published
2020
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13. GARFIELD-AF: risk profiles, treatment patterns and 2-year outcomes in patients with atrial fibrillation in Germany, Austria and Switzerland (DACH) compared to 32 countries in other regions worldwide

Author

Haas, S., Camm, J.A., Harald, D., Steffel, J., Virdone, S., Pieper, K., Brodmann, M., Schellong, S., Misselwitz, F., Kayani, G., Kakkar, A.K., Jean-Pierre, B., John Camm, A., Fitzmaurice, D.A., Fox, K.A.A., Gersh, B.J., Goldhaber, S.Z., Shinya, G., Sylvia, H., Werner, H., Mantovani, L.G., Frank, M., Pieper, K.S., Turpie, A.G.G., Martin van Eickels, Verheugt, F.W.A., Fox Bernard, K.A.A., Gersh, J., Hector, L., Luciardi Harry Gibbs, Marianne, B., Frank, C., Antonio Carlos Pereira Barretto, Connolly, S.J., John, E., Ramon, C., Zhi-Cheng, J., Petr, J., Jørn Dalsgaard Nielsen, Hany, R., Pekka, R., Jean-Yves Le Heuzey, Matyas, K., Jitendra Pal Singh Sawhney, Giancarlo, A., Giuseppe, A., Yukihiro, K., Carlos Jerjes Sánchez Díaz, Hugo Ten Cate, Dan, A., Janina, S., Elizaveta, P., Toon Wei Lim, Barry, J., Seil, O., Xavier, V., Marten, R., Jan, S., Pantep, A., Ali, O., Alex, P., Wael Al Mahmeed, David, F., Samuel, Z.G., Dayi Hu Kangning Chen, Yusheng, Z., Huaiqin, Z., Jiyan, C., Shiping, C., Daowen, W., Yuejin, Y., Weihua, L., Hui, L., Yuehui, Y., Guizhou, T., Ping, Y., Yingmin, C., Shenghu, H., Yong, W., Guosheng, F., Xin, L., Tongguo, W., Xiaoshu, C., Xiaowei, Y., Ruiping, Z., Moshui, C., Longgen, X., Ping, C., Yang, J., Ying, G., Xue, L., Zhiming, Y., Praveen Jadhavm Raghava Sarma, Govind, K., Prakash, C., Rasesh Atulbhai Pothiwala, Mohanan Padinhare Purayil, Kamaldeep, C., Veerappa Annasaheb Kothiwale, Bagirath, R., Vinod Madan Vijan, Jitendra, S., Ganapathi, B., Aziz, K., Ramdhan, M., Manojkumar, C., Sunitha, A., Vikas, B., Govindan, V., Debabrata, R., Rajashekhar, D., G Ravi Shankar, A., Sunil, K., Dinesh, J., Kartikeya, B., Vinay, K., Udigala Madappa Nagamalesh, Rajeeve Kumar Rajput, Yukihiro Koretsune Seishu Kanamori, Kenichi, Y., Koichiro, K., Yosuke, K., Keiki, Y., Fumitoshi, T., Yuji, M., Ikuo, M., Hiroo, N., Shinichi, A., Tetsuro, S., Masahiro, M., Hiroyuki, O., Susumu, A., Kei, C., Hiroaki, N., Makoto, T., Takeshi, K., Kunihiko, Y., Hiroshi, A., Takayuki, H., Megumi, O., Shiro, A., Shinichiro, K., Kenshi, K., Takashi, M., Jun, M., Yurika, O., Ryuji, S., Kazuo, G., Kotaro, M., Yoshikuni, H., Hisakazu, S., Hiroo, M., Hitoshi, K., Tsugihiro, N., Tadashi, N., Hidekazu, N., Ryuji, Z., Yoshihisa, F., Akira, Y., Hiroyuki, N., Jun, O., Yasuyuki, K., Kinshiro, M., Yutaka, W., Masanori, Y., Hiromitsu, M., Sumihisa, A., Hajime, K., Satoru, T., Katsumi, S., Hiroki, T., Ichiro, O., Takashi, K., Satoshi, H., Masamichi, G., Takuma, E., Hidetoshi, C., Kazuaki, F., Yuhei, S., Hirokuni, S., Toshihisa, N., Yoshihiko, A., Toshiro, N., Kazuhisa, S., Fumihiro, H., Naoto, Y., Masahiro, K., Toshifumi, T., Munesumi, I., Yoshitake, F., Daisuke, I., Taku, S., Tetsu, I., Norio, I., Koichi, O., Keizo, T., Yutaka, H., Motoshi, T., Hiroto, T., Shinjiro, N., Masaaki, I., Yuichiro, N., Naomasa, M., Ashida, K., Jun, A., Seishiro, M., Osamu, A., Shuji, F., Hirofumi, M., Kazuya, M., Yoshiki, H., Ichiro, S., Kotaro, O., Ichiro, T., Mitsuyuki, A., Toshihide, U., Yoshinori, G., Makoto, I., Shoji, M., Shigeru, M., Hideo, D., Mitsuru, T., Takaaki, K., Shigeo, K., Chiga, O., Masaki, S., Masami, N., Yutaka, K., Yoichi, N., Hiroshi, O., Rikimaru, O., Masato, A., Teruaki, M., Kazuhiko, N., Takafumi, M., Junichi, M., Mitsunori, A., Masako, F., Makoto, O., Tsuneo, F., Toshiya, T., Tenei, K., Hiroshi, K., Mizuho, I., Masahiro, A., Takashi, U., Hironori, O., Masahiko, I., Yoshiki, K., Atsuyuki, N., Shinobu, T., Mitsuhiro, S., Masayuki, N., Kenichiro, I., Motoyuki, I., Taro, M., Masamichi, W., Hiroaki, M., Masato, M., Fumio, O., Teruaki, K., Kuniaki, T., Masaaki, T., Morio, I., Hiroshi, W., Toshihiko, S., Shinya, H., Hiroaki, H., Mitsumoto, H., Michitaka, H., Koichi, M., Hideki, H., Nobuyoshi, S., Yukio, S., Akira, S., Kazuo, N., Tetsuro, Y., Kunio, A., Sen, A., Chiei, T., Saori, M., Hirofumi, K., Masanori, K., Shiro, N., Atsushi, T., Shuta, T., Kazuyuki, S., Akiko, M., Hiroki, S., Jin, N., Taketo, H., Takash, I., Kazuki, S., Kazuya, K., Tomobumi, K., Tsuyoshi, T., Hirosumi, S., Kiyoshi, N., Kenichi, I., Kazuo, M., Tomohiro, S., Takeshi, I., Koichi, K., Hiromichi, K., Tsutomu, T., Mamoru, H., Jisho, K., Akitoshi, S., Yoshihiro, T., Tetsuo, B., Koji, H., Masaaki, H., Koichi, H., Takao, B., Kazuaki, M., Toshihiko, K., Kunihiko, H., Toshihide, K., Akira, N., Eiji, O., Takashi, S., Hiroyoshi, H., Chikako, S., Takashi, Y., Ichiro, M., Kazunori, S., Isamu, N., Ken, T., Osamu, I., Koichi, T., Samu, U., Hirokazu, K., Takuya, O., Seizo, O., Junya, K., Toshihiko, N., Itaru, M., Yoshifusa, M., Yasuyuki, M., Kazuo, T., Hajime, H., Tetsutaro, K., Koji, M., Masaichi, N., Takashi, W., Tomoki, Y., Masato, S., Hidekazu, A., Hisanori, S., Hiroyuki, T., Nobufusa, F., Akira, O., Kentaro, Y., Kenji, A., Taku, Y., Takeaki, K., Shunji, S., Shu, S., Nitaro, S., Masayuki, W., Yosuke, N., Toru, A., Masaki, O., Tetsushi, W., Tomoko, K., Yasuo, S., Takeshi, T., Yoshihito, H., Shinichi, H., Yukihiko, A., Yoshihiro, S., Hirohide, U., Hiroshi, T., Shuichi, T., Naoto, H., Seiichi, M., Hisashi, S., Takuma, A., Yasunobu, S., Yawara, N., Osamu, M., Hideko, I., Katsumasa, N., Masatsugu, N., Kazuo, S., Toshiyuki, F., Nobuhisa, I., Shunichi, N., Kiyoharu, S., Yujin, S., Naoko, O., Teruhiko, K., Hideaki, O., Masato, E., Tsutomu, G., Makoto, H., Emiko, N., Noriyuki, N., Toshizumi, M., Shuichi, S., Katsuhiro, O., Yoko, E., Tsuyoshi, F., Haruhiko, D., Shuichi, K., Sho, N., Yuya, U., Tetsuro, F., Mitsuru, I., Takuo, O., Shunsuke, T., Hideo, I., Norihiko, S., Kiyomitsu, I., Nobuo, W., Masatake, A., Junji, D., Tetsuya, K., Masato, T., Naoya, M., Yasuaki, F., Wataru, F., Susumu, S., Akinori, F., Ryosai, N., Hiroyasu, K., Rei, F., Keijiro, N., Yoji, K., Junya, A., Kiyoshi, Y., Toshio, A., Yasuhiro, S., Tatsuo, H., Yuichiro, K., Yasuhide, S., Yukihiro, S., Shingo, M., Kojuro, M., Yasuko, S., Toyoshi, S., Fumiko, I., Toshiyuki, K., Jaeyoung, K., Hiroshi, Y., Yoichi, T., Yoko Onuki Pearce, Yasuyuki, S., Takayuki, F., Toru, N., Hideaki, K., Yoshiyuki, K., Tetsuji, I., Hironori, M., Yasufumi, M., Masahito, S., Shimato, O., Yutaka, O., Satoshi, U., Kojiro, K., Tatsuo, O., Naoki, M., Koichi, I., Atsushi, I., Tomohiro, Y., Toshihiro, G., Tsukasa, K., Atsushi, S., Etsuo, M., Toshio, T., Hiroshi, S., Shunichi, F., Tomohiro, K., Yoshiyuki, F., Hiroshi, H., Jun, N., Kiichiro, Y., Takuya, I., Takafumi, A., Chi Keong Ching Toon Wei Lim, Kelvin, W., Tan, Y., Seil Oh Hui Nam Park, Woo-Shik, K., Hyeyoung, L., Sung-Won, J., Dae Hyeok Kim, Jun, K., Dongryeol, R., Jaemin, S., Dae-Kyeong, K., Dong Ju Choi, Yong Seog Oh, Myeong-Chan, C., Hack-Lyoung, K., Hui-Kyung, J., Dong-Gu, S., Sang Weon Park, Hoon Ki Park, Sang-Jin, H., Jung Hoon Sung, Hyung-Wook, P., Gi-Byoung, N., Young Keun On, Hong Euy Lim, Jaejin, K., Tae-Joon, C., Taek Jong Hong, Seong Hoon Park, Jung Han Yoon, Nam-Ho, K., Kee-Sik, K., Byung Chun Jung, Gyo-Seung, H., Chong-Jin, K., Sakda Rungaramsin Peerapat Katekangplu, Porames, K., Thanita, B., Wanwarang, W., Pinij, K., Khanchai, S., Waraporn, T., Supalerk, P., Khanchit, L., Doungrat, C., Warangkana, B., Sirichai, C., Songkwan, S., Pisit, H., Seksan, C., Pairoj, C., Boonsert, C., Yingsak, S., Khompiya, K., Piya, M., Sasivimon, J., Ongkarn, K., Armagan Altun Ali Aydinlar, Ramazan, T., Zeki, O., Sadik, A., Durmus Yildiray Sahin, Ozcan, Y., Mehmet Birhan Yilmaz, Hasan, P., Mesut, D., Murat, S., Levent, S., Murat, E., Ertugrul, O., Dursun, A., Florencia Rolandi Adrian Cesar Ingaramo, Gustavo Alberto Sambadaro, Vanina Fernandez Caputi, Sofia Graciela Berman, Pablo, D., Andres Javier Kleiban, Nestor, C., Rodolfo Andres Ahuad Guerrero, Leonel Adalberto Di Paola, Ricardo Dario Dran, Javier, E., Matias Jose Fosco, Victor Alfredo Sinisi, Luis Rodolfo Cartasegna, Oscar Gomez Vilamajo, Jose Luis Ramos, Sonia, S., Gerardo, Z., Diego, C., Guillermo, G., Alberto Alfredo Fernandez, Mario Alberto Berli, Fabian, F., Dário Celestino Sobral Filho Jefferson Jaber, Luciana Vidal Armaganijan, Costantino Roberto Frack Costantini, André, S., Weimar Kunz Sebba Barroso de Souzaem, João David de Souza Neto, José Márcio Ribeiro, Marcelo Silveira Teixeira, Paulo, R., Leonardo, P., Daniel, M., José Carlos Moura Jorge, Adalberto Menezes Lorga Filho, Luiz, B., Marcelo Westerlund Montera, Carlos Henrique Del Carlo, Jamil Abdalla Saad, Fernando Augusto Alves da Costa, Renato, L., Gilson Roberto de Araújo, Euler Roberto Manenti, Jose Francisco Kerr Saraiva, João Carlos Ferreira Braga, Alexandre, N., Carlos, M., Dalton, P., Fernando, R., Gilmar, R., Roberto Álvaro Ramos Filho, Estêvão Lanna Figueiredo, Roberto Vieira Botelho, Cláudio Munhoz da Fontoura Tavares, Helius Carlos Finimundi, Adriano, K., César Cássio Broilo França, Fábio, A., Guido Bernardo Aranha Rosito, João Batista de Moura Xavier Moraes Junior, Rogério Tadeu Tumelero, Lilia, M., Roberto Simões de Almeida, Ney Carter do Carmo Borges, Luís Gustavo Gomes Ferreira, Ramón Corbalán Benjamin Aleck Joseh Stockins Fernandez, Humberto, M., Fernando, L., Martín Larico Gómez, Carlos, A., Carlos, C., Patricio Marin Cuevas, Alejandro, F., Claudio Bugueño Gutiérrez, Juan, A., Sergio Potthoff Cardenas, German, E., Cesar, H., Carlos, R., Germán, A., Gustavo Charme Vilches, Carlos Jerjes Sanchez Diaz Jesus Jaime Illescas Diaz, Raul Leal Cantu, Maria Guadalupe Ramos Zavala, Ricardo Cabrera Jardines, Nilda Espinola Zavaleta, Enrique Lopez Rosas, Guillermo Antonio Llamas Esperón, Gerardo, P., Ernesto Cardona Muñoz, Norberto Matadamas Hernandez, Adolfo Leyva Rendon, Norberto Garcia Hernandez, Manuel de Los Rios Ibarra, Luis Ramon Virgen Carrillo, David Lopez Villezca, Carlos Hernandez Herrera, Juan Jose Lopez Prieto, Rodolfo Gaona Rodriguez, Efrain Villeda Espinosa, David Flores Martinez, Jose Velasco Barcena, Omar Fierro Fierro, Ignacio Rodriguez Briones, Jose Luis Leiva Pons, Humberto Alvarez Lopez, Rafael Olvera Ruiz, Carlos Gerardo Cantu Brito, Eduardo Julian Jose Roberto Chuquiure Valenzuela, Roxana Reyes Sanchez, Alberto Esteban Bazzoni Ruiz, Oscar Martin Lopez Ruiz, Roberto Arriaga Nava, Jesus David Morales Cerda, Pedro Fajardo Campos, Mario Benavides Gonzalez, Marianne Brodmann Kurt Lenz, Claus, H., Johannes, F., Heinz, D., Kurt, H., Andrea, P., Michael, W., Bruno, S., Alfons, G., Wilfried, L., Sabine, E., Peter, K., Josef, S., Heribert, R., Bernhard, S., Luc Capiau Geert Vervoort, Bart, W., Geert, H., Jan, V., Dirk, F., Yohan, B., Marc, D., Olivier, X., Harry, S., John, T., Georges, M., Wim, A., Ivan, B., Michel, B., Stefan, V., Peter, V., Philippe, P., Pascal, G., Tim, B., Philippe, D., Alex, H., Joeri, V., Axel De Wolf Eva Zidkova Petr Jansky, Rudolf, S., Vilma, M., Ondrej, L., Josef, O., Lubos, K., Blazej, R., Richard, F., Jan, H., Ilja, K., Zdenek, M., Hana, B., Ondrej, J., Jana, P., Iveta, P., Vratislav, D., Michaela, H., Petr, P., Petr, R., Jindrich, S., Miroslav, N., Vaclav, D., Katarina, P., Jiri, L., Jørn Nielsen Steen Husted, Helena, D., Ulrik, H., Søren, R., Næstved, S., Arne, B., John, M., Jan, B., Jorgen, S., Ebbe, E., Thomas, L., Michael, B., Jacob, M., Morten, S., Michael, O., Pekka Raatikainen Carmela Viitanen, Franck Paganelli Joël Ohayon, Frédéric, C., Michel, G., Yannick, G., Philippe, L., Jean-Joseph, M., Mohamed Bassel Koujan, André, M., Sylvain, D., Olivier, P., Nicolas, D., Jean-Pierre, C., Maxime, G., Dominique, G., G Lokesh, A., Mathieu, Z., Pierre, A., Emmanuel, E., James, K., Pierre-Yves, F., Jean-Pierre, H., Nestor, L., Gilles, R., Igor, S., Jean-Philippe, N., Marie Hélène Mahagne, Antoine, M., Marc, B., Jean-Baptiste, C., Vincent, N., Frederic, S., Gilles, M., Jean-Paul, B., Bernard, D., Michel, M., Désiré, O., Bernard, C., Joseph, M., Etienne, B., Jean Philippe Brugnaux, Alain, F., Pierre, N., Jean-Baptiste, B., Sebastien Schellong Harald Darius, Georg, K., Andreas, K., Uwe, G., Bernd-Thomas, K., Thomas, S., Jan, P., Enno, E., Heinz-Dieter, Z., Peter, R., Christoph, A., Gerd-Ulrich, H., Holger, M., Andreas, P., Stefan, Z., Wolfgang, E., Guenter, R., Dirk, G., Norbert, L., Petra, S., Henning, W., Cosmas, W., Steffen, S., Toralf, S., Adyeri, B., Maximilian, K., Hans-Hermann, Z., Friedhelm, K., Andreas, C., Sabine, O., Torsten, L., Hermann-Josef, H., Gunter, L., Hans-Walter, B., Gunter, H., Dietrich, R., Joachim, H., Praxis Dres Werner Erdle, Wilfried, D., Janna, D., Karl-Albrecht, R., Reinhold, V., Thomas, M., Peter, M., Uwe, H., Volker, E., Heinz, H., Heinz, L., Volker, L., Heiner, M., Christian, S., Herrmann, L., Thomas, B., Gunter, B., Susanne, K., Karsten, M., Sylvia, B., Muwafeg, A., Hans-Holger, E., Carsten, S., Peter, B., Laszlo, K., Britta, S., Wilhelm, H., Jens-Uwe, R., Andras Vertes Gabor Szantai, Andras, M., Nikosz, K., Zoltan, B., Erno, K., Balazs, G., Ferenc, J., Gizella, J., Sandor, K., Zoltan, L., Zsolt, M., Bela, M., Ebrahim, N., Tamas, H., Peter, P., Gabriella, S., Sandor, V., Andras, N., Gabriella, E., Judit, F., Mihaly, E., Giuliana Martini Leone Maria Cristina, Eros, T., Rita, S., Sophie, T., Giovanni Di Minno, Marco, M., Teresa Maria Caimi, Maria, T., Roberto, C., Daniela, P., Roberto, Q., Franco, C., Raffaele, F., Vincenzo, O., Raffaele, R., Roberto, S., Raimondo De Cristofaro, Giuliana, G., Angelo De Blasio, Jorge Salerno Uriate, Flavia, L., Enrico Maria Pogliani, Grzegorz, B., Michele, A., Antonio, M., Mauro, F., Arturo, R., Luciano, F., Andrea, M., Fabrizio, G., Luca, T., Maria, S., Sergio, N., Paolo, R., Antonio, A., Claudio, B., Filippo, T., Massimo, V., Maria, D., Maria Grazia Bongiorni, Silva, S., Alessandro, C., Corrado, L., Enrico, S., Gaetano, S., Tondo, C., Paolo, G., Carmine, M., Saverio, I., Hugo Ten Cate J, H.R., Andreas, L., Henk, A., Maarten, B., Mathijs, P., Coen van Guldener, Johannes, H., S H K P, R.N., Pieter, H., Walter, H., E Groenemeijer, B., Terpstra, W., Cees, B., L V, A.B., Eivind Berge Per Anton Sirnes, Erik, G., Torstein, H., Knut, E., Arne, H., Gunnar, S., Anders, Ø., Beraki, G., Arne, S., Peter, C., Torbjørn, Ø., Svein Høegh Henrichsen, Jan Erik Otterstad, Janina Stepinska Andrzej Gieroba, Malgorzata, B., Michal, O., Beata, W., Krystyna, L., Jaroslaw, Wieslaw, S., Jerzy, K., Roman, Z., Jaroslaw, H., Lucyna, S., Lech, K., Marcin, G., Piotr, M., Maciej, O., Grzegorz, K., Malgorzata, K., Zbigniew, L., Bozenna, O., Jerzy, L., Elzbieta, Z., Agnieszka, K., Malgorzata, C., Iwona, W., Grzegorz, O., Marek, B., Marcin, O., Grazyna, G., Piotr, R., Grzegorz, S., Ryszard, S., Boguslaw, O., Piotr, K., Krzysztof, G., Krzysztof, C., Jaroslaw, J., Pawel, M., Waldemar, M., Stanislaw, M., Roman, L., Jacek, B., Teresa, R., Grzegorz, R., Ewa, D., Jadwiga, N., Jozef, L., Vera Eltishcheva Roman Libis, Gadel, K., Dmitry, B., Liudmila, E., Alexander, K., Eduard, Y., Dmitry, Z., Olga, B., Olga, M., Evgeniy, M., Konstantin, Z., Tatyana, N., Yulia, M., Elena, P., Konstantin, S., Maria, R., Yulia, S., Alla, K., Konstantin, N., Oksana, Z., Anna, Z., Victor, K., Sergey, P., Maria, P., Anton, E., Elena Aleksandrova Oksana Drapkina, Alexander, V., Oleg, N., Petr, C., Svetlana, R., Mikhail, S., Borys, K., Alexey, U., Xavier Vinolas Pere Alvarez Garcia, Maria Fernanda Lopez Fernandez, Luis Tercedor Sanchez, Salvador Tranche Iparraguirre, Pere Toran Monserrat, Emilio Marquez Contreras, Jordi Isart Rafecas, Juan Motero Carrasco, Pablo Garcia Pavia, Casimiro Gomez Pajuelo, Luis Miguel Rincon Diaz, Luis Fernando Iglesias Alonso, Angel Grande Ruiz, Jordi Merce Klein, Jose Ramon Gonzalez Juanatey, Ines Monte Collado, Herminia Palacin Piquero, Carles Brotons Cuixart, Esther Fernandez Escobar, Joan Bayo, I.L., Cecilia Corros Vicente, Manuel Vida Gutierrez, Francisco Epelde Gonzalo, Carlos Alexandre Almeida Fernandez, Encarnacion Martinez Navarro, Juan Jose Montero Alia, Maria Barreda Gonzalez, Maria Angels Moleiro Oliva, Jose Iglesias Sanmartin, Mercedes Jimenez Gonzalez, Maria Del Mar Rodriguez Alvarez, Juan Herreros Melenchon, Tomas Ripoll Vera, Manuel Jimenez Navarro, Maria Vazquez Caamano, Maria Fe Arcocha Torres, Gonzalo Marcos Gomez, Andres Iniguez Romo, Miguel Angel Prieto Diaz, Mårten Rosenqvist Alexander Wirdby, Centrumkliniken, Jan, L., Kerstin, H., Micael, E., Arnor, E., Ulf, B., Liu, B., Anders, L., Lars-Bertil, O., Mikael, G., Lars, A., Lars, B., Claes, B., Ali, H., Björn, M., Marianne, E., Åke, O., Håkan, L., Peter, S., Katarina, T., Hans, H., Pyotr, P., Fredrik, B., Ingar, T., Milita, C., Jan-Erik, K., Agneta, A., Lennart, M., Johan, E., Jörgen, T., Aida, H., Steen, J., Per, S., Jan Steffel Johann Debrunner, Juerg, H.B., Dipen, S., Iurii Rudyk Vira Tseluyko, Oleksandr, K., Svitlana, Z., Igor, K., Oleksandr, P., Iryna, K., Nestor, S., Yuriy, M., Oleksiy, U., Olena, K., Yevgeniya, S., Oleg, S., Mykola, S., Andriy, Y., Susanna, T., Ivan, F., Will Murdoch Naresh Chauhan, Daryl, G., Louise, L., Ramila, P., Philip, S., Bennett, W., Alex, C., Niranjan, P., Jhittay, P., Andrew, R., S Kainth, M., Karim, L., Kevin, D., Gill, P., Joanna, M., Laura, H., Trevor, G., Helga, W., Cumberlidge, Colin, B., Catherine, B., Kevin, J., Shoeb, S., Richard, C., Bhupinder, S., Willcock, W., Sircar, S., John, C., Gilliand, A., Roman, B., Strieder, E., Peter, H., Anne, W., Michael, S., Graham, K., Bhaskhar, V., Nigel, B., Paul, E., Clark, M., John, B., Jennifer, L., Fisher, E., Tim, F., Richard, K., Neil, P., Elizabeth, A., Michael, A., Ramesh, C., Pete, W., Simon, F., Sue, F., Julian, T., Hasan, C., Gary, T., Dawn, T., Matt, P., Claire, S., Carolyn, P., Mark, R., Angus, J., Helen, S., Hywel, J., Claire, G., Matthew, B., Philip, W., Jehad, A., Simon, W., William, L., Phil, E., Frances, S., Neil, M., Stephen, R., Yvette, S., Richard, W., Philip, P., Paul, W., Preeti, P., Andrew, G., Railton, T., Emyr, D., Jonathan, M., Marc, J., Claire, H., Thompson, R., Bijoy, S., Keith, B., Susan, B., Helen, L., David, R., Ulka, C., Ikram, H., Paul, A., Claire, J., Phil, W., Jane, E., Lisa, G., Janet, G., Alison, M., Poland, K., Conor, M., Warke, A., Paul, C., Burns, D., Smith, R., Kamath, R., Jonathan, W., Ian, H., Stephen, V., Paul, R., Hilary, P., Jayesh, P., Amar, A., Nigel, H., Richard, D., Nigel, D., Catherine, N., Mark, D., Purnima, S., Sophia, G., Charlotte, H., Raife, O., Martin, A., Mira, P., Gordon, I., Shahid, A., Catherine, R., Fiaz, C., Sabrina, K., Stephanie, S., Sharon, P., Warwick, C., Neil, R., Amy Butler Steven Coates, Ben, W., Daniel, J., Steve, W., Diane, S., Toh, W., Mark, B., Melanie, D., David, C., Sarah, D., Ben, F., Nick, H., Henry, C., Jon, S., Tim, M., Salah, E., Diane, G., Justin, W., Richard, V., Karen, F., Rob, H., Kashif, Z., Catherine, L., Rebecca, W., Paul, M., Andre, B., Philip, C., Mike, W., Mark, P., Chaminda, D., Greg, R., James, B., Polly, J., Rajesh, M., Matthew, A., Robin, F., Nicolas, T., Simon, C., Rory, R., Simon, R., Christine, A., Ann, F., Andrew, H., Simon, D., Minnal, N., Iain, M., Jane, G., Phil, S., John, S., Emma, B., Adam Blenkhorn Bhuwanendu Singh, Penny, A., William van Gaal, Walter, A., Philip, T., Ron, L., Jens, K., Andrei, C., Hosen, K., David, E., John, F., Bronte, A., Thanh, P., James, R., David, O., Sang Cheol Bae, Harry, G., Patrick, C., Greg, S., Margaret, A., Maurits, B., Astin, L., John Eikelboom Robert Luton, Milan, G., Amritanshu Shekhar Pandey, Stephen, C., Rolland, L., Philippe, B., Félix, A., Joseph, B., John, H., Germain, P., Miranda du Preez, Bradley, S., Reginald, N., Ripple, D., Tomasz, H., Andrea, L., Ratika, P., James, C., Benoit, C., Brian, R., Jorge, B., Saul, V., Sameh, F., Ahmed Mowafy Azza Katta, Mazen, T., Moustafa, N., Mohamed, S., Seif Kamal Abou Seif, Tarek, K., Ahmed Abd El-Aziz, Nasser, T., Ashraf, R., Atef, E., Mohamed Gamal El Din, Magdi, E., Adel, E., David Kettles Junaid Bayat, Heidi, S., Adrian, H., Ynez, K., Riaz, G., Thayabran, P., Michele, G., Louis van Zyl, Hendrik, T., Andrew, M., Rikus, L., Deon, G., Pindile, M., Siddique, I., Fayzal, A., Johannes, E., Shambu, M., Wessel, O., Rehana, L., Veronica, U., Wael AlAl Mahmeed AbdullahNaeemi, Ghazi, Y., Nooshin, B., Munther, A., Rajan, M., Rupesh, S., Ahmed, N., Mohamed, I., Amrish, A., Mukesh, N., Ehab, M.E., Adel, W., Rajeev, G., Michael Cox Scott Beach, Peter, D., Stephen, F., Kevin, F., Miguel, F., W Michael Kutayli, Annette, Q., Niraj, S., Vance, W., Stephen, M., Mark, A., Edwin, B., Roddy, C., Ted, G., Rodney, I., Jorge, G., Howard, N., Pamela, R., Rajneesh, R., Marcus, W., Daniel, N., Keith, F., Ihsan, H., Robert, M., Sridevi, P., Daniel, T., Charles, T., Moustafa, M., Cas, C., Walter, P., Alisha, O., George, P., Jaspal, G., James, W., and Firas, K. more...

Subjects
Vitamin K antagonists, Atrial fibrillation, GARFIELD-AF, Non-vitamin K antagonist oral anticoagulants, Oral anticoagulation, Phenprocoumon, Settore MED/11 - Malattie dell'Apparato Cardiovascolare
Abstract

The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is a worldwide non-interventional study of stroke prevention in patients with non-valvular AF.52,080 patients with newly diagnosed AF were prospectively enrolled from 2010 to 2016. 4121 (7.9%) of these patients were recruited in DACH [Germany (n = 3567), Austria (n = 465) and Switzerland (n = 89) combined], and 47,959 patients were from 32 countries in other regions worldwide (ORW). Hypertension was most prevalent in DACH and ORW (85.3% and 75.6%, respectively). Diabetes, hypercholesterolaemia, carotid occlusive disease and vascular disease were more prevalent in DACH patients vs ORW (27.6%, 49.4%, 5.8% and 29.0% vs 21.7%, 40.9%, 2.8% and 24.5%). The use of non-vitamin K antagonist oral anticoagulants (NOACs) increased more in DACH over time. Management of vitamin K antagonists was suboptimal in DACH and ORW (time in therapeutic range of INR ≥ 65% in 44.6% and 44.4% of patients or ≥ 70% in 36.9% and 36.0% of patients, respectively). Adjusted rates of cardiovascular mortality and MI/ACS were higher in DACH while non-haemorrhagic stroke/systemic embolism was lower after 2-year follow-up.Similarities and dissimilarities in AF management and clinical outcomes are seen in DACH and ORW. The increased use of NOAC was associated with a mismatch of risk-adapted anticoagulation (over-and-undertreatment) in DACH. Suboptimal control of INR requires educational activities in both regional groups. Higher rates of cardiovascular death in DACH may reflect the higher risk profile of these patients and lower rates of non-haemorrhagic stroke could be associated with increased NOAC use. more...

Published
2022

14. Reconstruction of vertebral body in thoracolumbar AO type A post-traumatic fractures by balloon kyphoplasty: a series of 85 patients with a long follow-up and review of the literature

Author

FRANCAVIGLIA, Natale, primary, VILLA, Alessandro, additional, MAIELLO, Marco, additional, COSTANTINO, Gabriele, additional, ALESSANDRELLO, Raffaele F., additional, MELI, Francesco, additional, ODIERNA CONTINO, Antonino, additional, LIPANI, Rita, additional, FIORENZA, Vito, additional, LO DUCA, Benedetto, additional, ASCANIO, Francesco, additional, IACOPINO, Domenico G., additional, and MAUGERI, Rosario, additional more...

Published
2022
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15. Climate hazard indices projections based on CORDEX-CORE, CMIP5 and CMIP6 ensemble

Author

Coppola, E., Raffaele, F., Giorgi, F., Giuliani, G., Xuejie, G., Ciarlo, J.M., Sines, T.R., Torres-Alavez, J.A., Das, S., di Sante, F., Pichelli, E., Glazer, R., Müller, S.K., Abba Omar, S., Ashfaq, M., Bukovsky, M., Im, E.-S., Jacob, D., Teichmann, C., Remedio, A., Remke, T., Kriegsmann, A., Bülow, K., Weber, T., Buntemeyer, L., Sieck, K., and Rechid, D. more...

Abstract

The CORDEX-CORE initiative was developed with the aim of producing homogeneous regional climate model (RCM) projections over domains world wide. In its first phase, two RCMs were run at 0.22° resolution downscaling 3 global climate models (GCMs) from the CMIP5 program for 9 CORDEX domains and two climate scenarios, the RCP2.6 and RCP8.5. The CORDEX-CORE simulations along with the CMIP5 GCM ensemble and the most recently produced CMIP6 GCM ensemble are analyzed, with focus on several temperature, heat, wet and dry hazard indicators for present day and mid-century and far future time slices. The CORDEX-CORE ensemble shows a better performance than the driving GCMs for several hazard indices due to its higher spatial resolution. For the far future time slice the 3 ensembles project an increase in all temperature and heat indices analyzed under the RCP8.5 scenario. The largest increases are always shown by the CMIP6 ensemble, except for Tx > 35 °C, for which the CORDEX-CORE projects higher warming. Extreme wet and flood prone maxima are projected to increase by the RCM ensemble over the la Plata basin in South America, the Congo basin in Africa, east North America, north east Europe, India and Indochina, regions where a better performance is obtained, whereas the GCM ensembles show small or negligible signals. Compound hazard hotspots based on heat, drought and wet indicators are detected in each continent worldwide in region like Central America, the Amazon, the Mediterranean, South Africa and Australia, where a linear relation is shown between the heatwave and drought change signal, and region like Arabian peninsula, the central and south east Africa region (SEAF), the north west America (NWN), south east Asia, India, China and central and northern European regions (WCE, NEU) where the same linear relation is found for extreme precipitation and HW increases. Although still limited, the CORDEX-CORE initiative was able to produce high resolution climate projections with almost global coverage and can provide an important resource for impact assessment and climate service activities. more...

Published
2021
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21. A first-of-its-kind multi-model convection permitting ensemble for investigating convective phenomena over Europe and the Mediterranean

Author

Croatian Science Foundation, Ministerio de Economía y Competitividad (España), European Commission, German Research Foundation, Austrian Science Fund, Research Council of Norway, Fundação para a Ciência e a Tecnologia (Portugal), Department of Energy and Climate Change (UK), Federal Ministry of Education and Research (Germany), Department for Environment, Food & Rural Affairs (UK), Ministry of Education, Youth and Sports (Czech Republic), Agence Nationale de la Recherche (France), Coppola, Erika, Sobolowski, Stefan, Pichelli, E., Raffaele, F., Ahrens, B., Anders, I., Ban, Nikolina, Bastin, Sophie, Belda, Michael, Belusic, D., Caldas-Alvarez, A., Cardoso, Rita M., Davolio, S., Dobler, Andreas, Fernández, Jesús, Fita, L., Fumiere, Q., Giorgi, Filippo, Goergen, Klaus, Güttler, Ivan, Halenka, Tomáš, Heinzeller, D., Hodnebrog, Ø., Jacob, Daniela, Kartsios, Stergios, Katragkou, Eleni, Kendon, E., Khodayar, S., Kunstmann, H., Knist, S., Lavín, Alicia, Lind, P., Lorenz, Torge, Maraun, Douglas, Marelle, L., Meijgaard, E. van, Milovac, Josipa, Myhre, G., Panitz, H.-J., Piazza, M., Raffa, M., Raub, T., Rockel, B., Schär, C., Sieck, K., Soares, Pedro M. M., Somot, Samuel, Srnec, L., Stocchi, P., Tölle, M. H., Truhetz, H., Vautard, R., Vries, H. de, Warrach-Sagi, Kirsten, Croatian Science Foundation, Ministerio de Economía y Competitividad (España), European Commission, German Research Foundation, Austrian Science Fund, Research Council of Norway, Fundação para a Ciência e a Tecnologia (Portugal), Department of Energy and Climate Change (UK), Federal Ministry of Education and Research (Germany), Department for Environment, Food & Rural Affairs (UK), Ministry of Education, Youth and Sports (Czech Republic), Agence Nationale de la Recherche (France), Coppola, Erika, Sobolowski, Stefan, Pichelli, E., Raffaele, F., Ahrens, B., Anders, I., Ban, Nikolina, Bastin, Sophie, Belda, Michael, Belusic, D., Caldas-Alvarez, A., Cardoso, Rita M., Davolio, S., Dobler, Andreas, Fernández, Jesús, Fita, L., Fumiere, Q., Giorgi, Filippo, Goergen, Klaus, Güttler, Ivan, Halenka, Tomáš, Heinzeller, D., Hodnebrog, Ø., Jacob, Daniela, Kartsios, Stergios, Katragkou, Eleni, Kendon, E., Khodayar, S., Kunstmann, H., Knist, S., Lavín, Alicia, Lind, P., Lorenz, Torge, Maraun, Douglas, Marelle, L., Meijgaard, E. van, Milovac, Josipa, Myhre, G., Panitz, H.-J., Piazza, M., Raffa, M., Raub, T., Rockel, B., Schär, C., Sieck, K., Soares, Pedro M. M., Somot, Samuel, Srnec, L., Stocchi, P., Tölle, M. H., Truhetz, H., Vautard, R., Vries, H. de, and Warrach-Sagi, Kirsten more...

Abstract

A recently launched project under the auspices of the World Climate Research Program’s (WCRP) Coordinated Regional Downscaling Experiments Flagship Pilot Studies program (CORDEX-FPS) is presented. This initiative aims to build first-of-its-kind ensemble climate experiments of convection permitting models to investigate present and future convective processes and related extremes over Europe and the Mediterranean. In this manuscript the rationale, scientific aims and approaches are presented along with some preliminary results from the testing phase of the project. Three test cases were selected in order to obtain a first look at the ensemble performance. The test cases covered a summertime extreme precipitation event over Austria, a fall Foehn event over the Swiss Alps and an intensively documented fall event along the Mediterranean coast. The test cases were run in both “weather-like” (WL, initialized just before the event in question) and “climate” (CM, initialized 1 month before the event) modes. Ensembles of 18–21 members, representing six different modeling systems with different physics and modelling chain options, was generated for the test cases (27 modeling teams have committed to perform the longer climate simulations). Results indicate that, when run in WL mode, the ensemble captures all three events quite well with ensemble correlation skill scores of 0.67, 0.82 and 0.91. They suggest that the more the event is driven by large-scale conditions, the closer the agreement between the ensemble members. Even in climate mode the large-scale driven events over the Swiss Alps and the Mediterranean coasts are still captured (ensemble correlation skill scores of 0.90 and 0.62, respectively), but the inter-model spread increases as expected. In the case over Mediterranean the effects of local-scale interactions between flow and orography and land–ocean contrasts are readily apparent. However, there is a much larger, though not surprising, increase in the spread for more...

Published
2020

22. Humanising AI could lead us to dehumanise ourselves.

Author

Ciriello, Raffaele F and Chen, Angelina Ying

Subjects
DATA privacy, USER-generated content, SOCIAL bonds, MONETARY incentives, CHATGPT, LONELINESS
Abstract

The article discusses the implications of humanizing AI, particularly in the context of AI companions becoming more prevalent in society. It explores how attributing human qualities to AI could potentially lead to the dehumanization of ourselves. The authors highlight ethical concerns, such as the risk of diminishing genuine human connection and the potential erosion of privacy and autonomy through the collection and analysis of emotional data by AI companies. Regulators are urged to hold AI providers accountable and ensure transparency in their claims and data privacy policies. [Extracted from the article] more...

Published
2024

23. The AI sexbot industry is just getting started. It brings strange new questions - and risks.

Author

Ciriello, Raffaele F

Subjects
GENERATIVE artificial intelligence, INTERNET pornography, MANIPULATIVE behavior, ARTIFICIAL intelligence, CHATBOTS, LONELINESS
Abstract

The article discusses the rise of artificial intelligence (AI) in the sexbot industry and the potential implications for human relationships. It highlights the popularity of AI-powered virtual companions and the ability for users to form emotional attachments with them. The article also explores the ethical concerns surrounding the industry, such as the control that creators have over the behavior of these virtual companions and the potential for emotional manipulation. It emphasizes the need for society and the state to set clear boundaries and hold sexbot providers accountable. [Extracted from the article] more...

Published
2024

26. Anatomical variations of the internal jugular vein: The role of ultrasonography

Author

Lena, A, Raffaele, F, Lo Iacono, G, GERACI, Girolamo, CAJOZZO, Massimo, Lena A., Raffaele F., Lo Iacono G., Geraci G., Cajozzo M., Lena, A, Raffaele, F, Lo Iacono, G, Geraci, G, and Cajozzo, M

Subjects
Settore MED/18 - Chirurgia Generale, Anatomical variation, internal jugular vein, Anatomy, jugular vein, ultrasonography, ultrasonography
Abstract

Purpose: In many places, especially in emergency department, central venous catheter is still inserted using anatomical landmark guidance with a success rate up to 97.6% and complications up to 15%. This study was aimed to determine by the support of ultrasono-graphy (US) the anatomical variations of the internal jugular vein (IJV) in relation with other structures of the neck, such as the common carotid artery (CCA). Material and Methods: 830 patients requiring central vein catheterization (CVC) were in-cluded in the analysis. The position of the IJV in relation to the other structures of the neck was demonstrated by portable ultrasonography. Results: The mean diameter of IJV was 10.3 mm in right and 10.5 mm in left side of neck, in male (p > 0.05) and 9.1 mm in right and 10.5 mm in left side of neck, in female (p > 0.05). The mean distance between IJV and CCA was 1.9 mm in right and 1.7 mm in left side of neck in male, and 2.0 mm in right and 2.2 mm in left side of neck in female. The mean distance of IJV from the skin surface was 9.8 mm in right and 10.0 mm in left side of neck in male, and 12.1 mm in right and 12.5 mm in left side of neck in female. On 25.54% we observed variations of internal jugular vein site. On 3.97% we observed a small caliber of internal jugular vein that could complicate the catheterization of the vein. On 1.8% was diagnosed a thrombus of internal jugular vein, that is considered as an ab-solute contraindication for a CVC. Conclusion: Different patients had anatomical variations that are important and should be knowed, in order to reduce the possibility of severe complications. more...

Published
2014

27. A first-of-its-kind multi-model convection permitting ensemble for investigating convective phenomena over Europe and the Mediterranean

Author

Coppola, Erika, primary, Sobolowski, Stefan, additional, Pichelli, E., additional, Raffaele, F., additional, Ahrens, B., additional, Anders, I., additional, Ban, N., additional, Bastin, S., additional, Belda, M., additional, Belusic, D., additional, Caldas-Alvarez, A., additional, Cardoso, R. M., additional, Davolio, S., additional, Dobler, A., additional, Fernandez, J., additional, Fita, L., additional, Fumiere, Q., additional, Giorgi, F., additional, Goergen, K., additional, Güttler, I., additional, Halenka, T., additional, Heinzeller, D., additional, Hodnebrog, Ø., additional, Jacob, D., additional, Kartsios, S., additional, Katragkou, E., additional, Kendon, E., additional, Khodayar, S., additional, Kunstmann, H., additional, Knist, S., additional, Lavín-Gullón, A., additional, Lind, P., additional, Lorenz, T., additional, Maraun, D., additional, Marelle, L., additional, van Meijgaard, E., additional, Milovac, J., additional, Myhre, G., additional, Panitz, H.-J., additional, Piazza, M., additional, Raffa, M., additional, Raub, T., additional, Rockel, B., additional, Schär, C., additional, Sieck, K., additional, Soares, P. M. M., additional, Somot, S., additional, Srnec, L., additional, Stocchi, P., additional, Tölle, M. H., additional, Truhetz, H., additional, Vautard, R., additional, de Vries, H., additional, and Warrach-Sagi, K., additional more...

Published
2018
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28. SINGLE ACCESS THORACOSCOPY IN BENIGN AND MALIGN PLEURIC PATHOLOGY

Author

CAJOZZO, Massimo, GERACI, Girolamo, MODICA, Giuseppe, Lo Iacono, G, Palazzolo, M, Pinna, R, Lo Nigro, C, Tinaglia, T, Raffaele, F, Cajozzo, M, Lo Iacono, G, Palazzolo, M, Pinna, R, Lo Nigro, C, Tinaglia, T, Raffaele, F, Geraci, G, and Modica, G. more...

Subjects
THORACOSCOPY, AWAKE, Settore MED/21 - Chirurgia Toracica
Abstract

(OBJECTIVE) Jacobeus and Bethune performed thoracoscopy under local anaesthesia, already on early 1900. A single access associated with local anaesthesia aims to improve procedure tolerance, shorten recovery and reduce costs. (METHODS) Premedication consists of atropine 0.01 mg/kg and midazolam (0,02-0.04 mg/kg). Pain control and sedation was obtained by remifentanile (0.05-0.1 mcg/kg/min). Local anaesthesia was made with lidocaine and ropivacaine. An incision of 20 mm is realised at 6° intercostal space for the “single-access-technique”, and two incisions for the “2-trocars-technique” (15 mm at 5°space - 10 mm at 6°/7°space). The 5 mm 0° camera is preferred for single-access technique. The effusion is not totally drained in order to maintain the lung collapsed, getting a better view of pleural cavity. Otherwise, it could be useful insufflating CO2. Liquid samples, multiple biopsies and eventual pleurodesis are performed. (RESULTS) Two groups of patients with pleural effusion : 95pts treated with awake technique and 79pts under general anaesthesia (Mean age 69,7 vs 63,4 statistically different p more...

Published
2012

29. Infantile myofibromatosis of the soft palate

Author

Alessandro Bozzao, Giorgio Iannetti, Andrea Cassoni, Sara Buonaccorsi, Filippo Giovannetti, Guido Trasimeni, Valentini, Maria Teresa Fadda, Andrea Romano, San Raffaele F, and Terenzi

Subjects
medicine.medical_specialty, medicine.anatomical_structure, Otorhinolaryngology, Soft palate, business.industry, Infantile myofibromatosis, medicine, Surgery, General Medicine, medicine.disease, business, Dermatology
Published
2015

32. Variation of POP concentrations in fresh-fallen snow and air on an Alpine glacier (Monte Rosa)

Author

Finizio, A, Villa, S, Raffaele, F, Vighi, M, RAFFAELE, FRANCESCA, Finizio, A, Villa, S, Raffaele, F, Vighi, M, and RAFFAELE, FRANCESCA

Abstract

To understand better the mechanisms ruling the fate of POPs (persistent organic pollutants) in cold environments, a field campaign sampling fresh-fallen snow and air on an Alpine glacier was carried out during Summer 2003. The concentrations of all analyzed chemicals in fresh-fallen snow show a sharp decrease over time, particularly for the more volatile POPs, confirming the rather limited literature evidence of a rapid decline of such substances from the snowpack and/or ice. Even if the results presented here are preliminary and should be confirmed by further studies, some evidence of the influence of a night/day cycle of temperature on POP deposition and revolatilization mechanisms has been highlighted. Finally, the role of cold condensation and long-range atmospheric transport in the contamination of higher altitudes in this Alpine system has been substantiated, particularly for OC pesticides more...

Published
2006

34. Utility of laser microdissection and pressure catapulting in the diagnosis of non small cell lung cancer: Preliminary data

Author

Cajozzo, M., Raffaele, F., Lo Iacono, G., Rizzo, S., Bazan, V., Russo, A., Calvo, D., Mario Barone, Migliore, M., CAJOZZO, m, RAFFAELE, f, LO IACONO, g, RIZZO, BAZAN, v, RUSSO, a, CALVO, d, BARONE, m, and MIGLIORE, m more...

Subjects
Lung cancer, bronchoscopy, Laser Microdissection Pressure Catapulting, molecular analysis
Abstract

Background: There are controversies about the adequacy of tumor tissue sample on which the sequencing of molecular diagnosis could be performed to achieve the targeted-therapy on lung cancer. The aim of this study is to demonstrate the role of the Laser Microdissection Pressure Catapulting (LMPC) technique to obtain adequate tumor tissue sample for the molecular analysis of gene mutations in the target therapy of lung cancer. Findings: From a consecutive series of 24 patients with a diagnosis of locally-advanced or metastatic Non Small Cell Lung Cancer (NSCLC), we performed 29 diagnostic procedures using the system of LMPC, to obtain an homogeneous samples where it was possible to run the sequencing of the 4 most frequently mutated exons of Epidermal Growth Factor Receptor (EGFR) (exon 18, 19, 20, 21). Results: There were 14 males (58.3%) and 10 females (41.7%), with a mean age of 61 years old. Twenty one patients were affected by adenocarcinomas, 2 by squamous cell carcinomas and 1 by large cell carcinoma. We were able to obtain the sequencing on 26 out 29 samples (89,6%) for EGFR mutation. EGFR mutation rate in our population was 7,7%. In 5 samples, we found a polymorphism in exon 20 and one of them carried a mutation on exon 18 as well. In another sample we found the deletion of exon 19. On the other 20 samples we did not find any mutation. Conclusions: Our preliminary data suggest that the LMPC technique permits to obtain the tumor cells sample more homogeneous facilitating the application of biological molecular analysis for EGFR-gene mutation in a larger number of patients with NSCLC. more...

35. One shoot seldinger central venous catheterization in dialyzed patients

Author

Cajozzo, M., Palumbo, V. D., Damiano, G., Maione, C., GIOVANNI TOMASELLO, Raffaele, F., Buscemi, S., Sinagra, E., Luca, S. D., Ficarella, S., Cocchiara, G., Cudia, B., Carlo, G. D., Fatica, F., Fazzotta, S., Fiorello, L., Maffongelli, A., Carmina, L., Buscemi, G., Lo Monte, A. I., Cajozzo, M, Palumbo, VD, Damiano ,G, Maione, C, Tomasello, G, Raffaele, F, Buscemi, S, Siangra, E, De Luca, S, Ficarella, S, Cocchiera, G, Cudia, B, Di Carlo, G, Fatica, F, Fazzotta, S, Fiorello, L, Maffongeli, A, Carmina, L, Buscemi, G, and Lo Monte, AI more...

Subjects
Central venous catheterization, CVC, ultrasound guide, end stage renal disease, dialysis, Settore MED/18 - Chirurgia Generale
Abstract

Introduction: Central Venous Catheterization is necessary in uremic patient (before dialysis) and many other conditions. In this study we demonstrated the advantages of ultrasonography to perform the procedure. Materials and methods: 48 uremic patient were submitted to ultrasound-guided central venous catheterization. The procedure was performed following the Seldinger “one shot” technique. Results: The mean operative time was 4 minutes, with a high rate of success (100%) and a low percentage of complications (2%). Conclusion: The ultrasound-guided central venous catheterization is a safe procedure, rapid and easy to perform. The procedure has a low rate of failures and complications and a high rate of success. It is suitable in all patients with vascular anatomical variations, “difficult neck”, or coagulation disorders. more...

37. Bi-Hamiltonian structure of the oriented associativity equation.

Author

Maxim V Pavlov and Raffaele F Vitolo

Subjects
*HAMILTONIAN operator, *ALGEBRAIC geometry, *ASSOCIATIVE algebras
Abstract

The oriented associativity equation plays a fundamental role in the theory of integrable systems. In this paper we prove that the equation, besides being Hamiltonian with respect to a first-order Hamiltonian operator, has a third-order non-local homogeneous Hamiltonian operator belonging to a class which has been recently studied, thus providing a highly non-trivial example in that class and showing intriguing connections with algebraic geometry. [ABSTRACT FROM AUTHOR] more...

Published
2019
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42. Endoscopic palliative management of esophageal and tracheal rupture

Author

Carmelo Sciumè, Giuseppe Modica, Girolamo Geraci, Francesco Raffaele, Geraci G., Raffaele F., Modica G., Sciume C., Geraci, G, Raffaele, F, Sciume', C, and Modica, G

Subjects
medicine.medical_specialty, Palliative care, Tracheal rupture, medicine.medical_treatment, MEDLINE, Text mining, tracheal rupture, medicine, Intubation, Intratracheal, Intubation, Humans, Endoscopy, Digestive System, endoscopy, Esophageal Perforation, medicine.diagnostic_test, business.industry, General surgery, Palliative Care, Gastroenterology, Esophageal rupture, Middle Aged, Endoscopy, Settore MED/18 - Chirurgia Generale, stent, Female, Stents, business
Abstract

The increasing number of patients requiring intensive care and airway support has led to a growing recognition that significant short- and long-term morbidity may be associated with the use of artificial airways; this is despite significant improvements in the materials used in laryngeal tubes, which aim to decrease the trauma associated with long-term intubation. We present the first case, to our knowledge,of huge, nontraumatic, esophageal perforation, widely communicating with the trachea, and which was treated successfully with double endoscopic stent placement. more...

Published
2014

43. Repertori paremiologici tra meteorologia, paesaggio agrario, mondo animale e spazialità geografico-culturale

Author

Roberto Sottile, Francesco Scaglione, Valenti, I, Abbamonte, R, Barbadillo de la Fuente, MT, Baumann, B, Bottoni, P, Carbone, F, Castagneto, M, Castiglione, A Cerruto, S, Emmi, T, D. García-Page Sánchez, M, García Romero, F, E. Koesters Gensini, S, Iacobini, C, Lalicata, M, Lapedota, DD, Longobardi, F, Manco, A, Mantione, F, Menza, S, Messina Fajardo, L, Nuccorini, S, Obstová, Z, Parente, E, Pavone, L, Prandi, M, Raffaele, F, Rocca, G, Romano, M, Rossi, M, Sălișteanu, O, Scaglione, F, Sciutto, V, Scivoletto, G, Sgroi, SC, Sommella, M, Sottile, R, Tramutoli, R, Khanh Van Tran Thi, Salvatore C. Trovato, Vedovelli, M, Vietri, S, Roberto Sottile, and Francesco Scaglione more...

Subjects
Settore L-FIL-LET/12 - Linguistica Italiana, proverbs, geolinguistics, geoparemiology, totemism
Abstract

The work focusses on a “geolinguistic” analysis of a group of proverbs from the area of Madonie (Sicily) collected in Sottile-Genchi (2011). The aim of the article is to shed light on the relation between the paremiologic repertoire and the main geographic and cultural features characterising the geographic area. In particular, this aspect implies both a paremiologic (micro)variation depending on the geomorphological peculiarities of each spot and an analysis of the relationship among those (humans and animals) who share the same places by which discover old superstitions and a specific socio-cultural background. more...

Published
2020

44. Mediastinal syndrome from plasmablastic lymphoma in human immunodeficiency virus and human herpes virus 8 negative patient with polycythemia vera: a case report

Author

Giuseppe Damiano, Francesco Paolo Caronia, Salvatore Dioguardi, Ada Maria Florena, Gerlando Cocchiara, Daniela Cabibi, Antonio Bruno, Massimo Cajozzo, Salvatore Buscemi, Francesco Raffaele, Attilio Ignazio Lo Monte, Vincenzo Davide Palumbo, F. Fatica, Antonino Alessio Anzalone, Cajozzo, M., Palumbo, VD, Buscemi, S., Damiano, G., Florena, A., Cabibi, D., Raffaele, F., Anzalone, A., Fatica, F., Cocchiara, G., Dioguardi, S., Bruno, A., Caronia, FP, and Lo Monte, AI more...

Subjects
Male, Pathology, Settore MED/21 - Chirurgia Toracica, Case Report, Settore MED/15 - Malattie Del Sangue, 0302 clinical medicine, Polycythemia vera, Polycythemia Vera, Case report, Fine-needle aspiration biopsy, Hematology, Rare clinical case, Thoracic surgery, Medicine (all), Ultrasonography, Medicine(all), Superior vena cava syndrome, medicine.diagnostic_test, Mediastinum, General Medicine, Herpesviridae Infections, Syndrome, Middle Aged, medicine.anatomical_structure, Treatment Outcome, 030220 oncology & carcinogenesis, Herpesvirus 8, Human, Plasmablastic Lymphoma, medicine.symptom, medicine.medical_specialty, Biopsy, Fine-Needle, Mediastinal Neoplasms, 03 medical and health sciences, Internal medicine, HIV Seronegativity, Biopsy, medicine, Humans, business.industry, Thrombosis, medicine.disease, Lymphoma, Settore MED/18 - Chirurgia Generale, Dyspnea, Cough, Jugular Veins, business, Diffuse large B-cell lymphoma, Plasmablastic lymphoma, 030215 immunology
Abstract

Background: Plasmoblastic lymphoma is a rare and aggressive subtype of diffuse large B cell lymphoma, which occurs usually in the jaw of immunocompromised subjects. Case presentation: We describe the occurrence of plasmoblastic lymphoma in the mediastinum and chest wall skin of an human immunodeficiency virus-negative 63-year-old Caucasian man who had had polycytemia vera 7 years before. At admission, the patient showed a superior vena cava syndrome, with persistent dyspnoea, cough, and distension of the jugular veins. Imaging findings showed a 9.7 × 8 × 5.7 cm mediastinal mass. A chest wall neoformation biopsy and ultrasound-guided fine-needle aspiration biopsy of the mediastinal mass allowed diagnosis of plasmoblastic lymphoma and establishment of an immediate chemotherapeutic regimen, with rapid remission of compression symptoms. Conclusions: Plasmoblastic lymphoma is a very uncommon, difficult to diagnose, and aggressive disease. The presented case represents the first rare mediastinal plasmoblastic lymphoma in a human immunodeficiency virus-/human herpesvirus-8-negative patient. Pathologists should be aware that this tumor does appear in sites other than the oral cavity. Fine-needle aspiration biopsy is a low-cost, repeatable, easy-to-perform technique, with a high diagnostic accuracy and with very low complication and mortality rates. Fine-needle aspiration biopsy could represent the right alternative to surgery in those patients affected by plasmoblastic lymphoma, being rapid and minimally invasive. It allowed establishment of prompt medical treatment with subsequent considerable reduction of the neoplastic tissue and resolution of the mediastinal syndrome. more...

Published
2017

45. 3D CT scan for perioperative identification of anatomical variations of lungs

Author

Girolamo Geraci, Francesco Raffaele, Gerlando Cocchiara, Massimo Cajozzo, Massimo Midiri, Filippo Caternicchia, Claudio Genova, F. Fatica, Giovanna Mancuso, Anna Galluzzo, Galluzzo A., Fatica F., Caternicchia F., Geraci G., Mancuso G., Raffaele F., Genova C., Cocchiara G., Midiri M., and Cajozzo M. more...

Subjects
Male, CT reconstruction, Cancer Research, medicine.medical_specialty, Lung Neoplasms, anatomic variations, lung surgery, Computed tomography, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Imaging, Three-Dimensional, Image Interpretation, Computer-Assisted, medicine, 3d ct scan, Image Processing, Computer-Assisted, Humans, Lung surgery, Perioperative Period, Pneumonectomy, Aged, Aged, 80 and over, Lung, medicine.diagnostic_test, Thoracic surgeon, business.industry, Thoracic Surgery, Video-Assisted, General Medicine, Perioperative, Middle Aged, medicine.anatomical_structure, Oncology, Cardiothoracic surgery, 030220 oncology & carcinogenesis, Female, Radiology, business, Tomography, X-Ray Computed, Ct reconstruction
Abstract

Aim: The aim of this study is to investigate anatomical lung variations and vascular patterns using volumetric 3D computed tomography (CT) representations. Methods & results: We considered 24 major thoracic surgery performed in our ward. In these, we discovered some interesting anatomical variations of the main pulmonary fissures. These findings were not visible on the plain x-ray or during routine examination of a preoperative CT scan. After re-examination of 3D CT scan reconstruction the anatomical variations were detected. Discussion: General thoracic surgeons must familiarize themselves with anatomical variations in lungs. 3D images may aid the general thoracic surgeon in performing safer surgeries. Conclusion: 3D CT scan should be performed before surgery if possible. more...

Published
2016
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46. Nodular histiocytic/mesothelial hyperplasia as consequence of chronic mesothelium irritation by sub-phrenic abscess

Author

Francesco Raffaele, Massimo Cajozzo, Antonio Pirrotta, Giorgio Lo Iacono, Sabrina Ingrao, F. Fatica, Salvatore Dioguardi, Daniela Cabibi, Cabibi, D., Iacono, G., Raffaele, F., Dioguardi, S., Ingrao, S., Pirrotta, A., Fatica, F., and Cajozzo, M more...

Subjects
Male, Cancer Research, Pathology, medicine.medical_specialty, Pleural effusion, Biopsy, Subphrenic abscess, Population, Settore MED/21 - Chirurgia Toracica, Settore MED/08 - Anatomia Patologica, Epithelium, Mesothelial hyperplasia, Thoracoscopy, Medicine, Humans, mesothelial hyperplasia, pleural effusion, VATS, education, education.field_of_study, Subphrenic Abscess, Hyperplasia, medicine.diagnostic_test, business.industry, Histiocytes, General Medicine, Middle Aged, medicine.disease, Mesothelium, medicine.anatomical_structure, Oncology, Pleura, business, Liver abscess
Abstract

Nodular histiocytic/mesothelial hyperplasia (NHMH) is a benign localized alteration, first described in 1975 by Rosai in the hernia sac [1]. Few pulmonary cases have been reported in literature [2–6]. Sometimes it has been reported in the pericardium [7,8] or presenting as an inguinal mass [9]. The ‘mesothelial/monocytic incidental cardiac excrescence’, first described by Weinot et al. in 1994 [10] is now considered a similar lesion to NHMH [11]. It consists of a reactive proliferation of histiocytes and mesothelium secondary to chronic irritation and it has been observed in pleura-damaging processes, such as pneumothorax [5], or as consequence of cardiac catheterization, inflammation, mechanical or tumor stimulation [11]. The rarity of NHMH and the moderate cytological atypia often present, make this lesion difficult to diagnose. It can be easily confused with primary mesothelial lesions and neoplasms such as adenocarcinomas, granulosa cell tumors or Langerhans’ histiocytosis. We report a case of pleural NHMH in a patient with a subphrenic abscess, in which no pulmonary pathogenic noxa was evident. We hypothesize a transdiaphragmatic chronic irritation as a pathogenetic mechanism underlying NHMH. more...

Published
2015

47. Thoracoscopy in pleural effusion –two techniques: awake single-access video-assisted thoracic surgery versus 2-ports video-assisted thoracic surgery under general anesthesia

Author

Girolamo Geraci, Salvatore Dioguardi, F. Fatica, Anzalone Aa, Francesco Raffaele, Massimo Cajozzo, Lo Iacono G, Cajozzo, M., Lo Iacono, G., Raffaele, F., Anzalone, A., Fatica, F., Geraci, G., and Dioguardi, S. more...

Subjects
Male, Cancer Research, medicine.medical_specialty, Pleural effusion, Sedation, medicine.medical_treatment, Settore MED/21 - Chirurgia Toracica, VATS, awake VATS, pleural effusion, single port, Anesthesia, General, Postoperative Complications, medicine, Thoracoscopy, Humans, Local anesthesia, General anaesthesia, Thoracotomy, Aged, Postoperative Care, medicine.diagnostic_test, Thoracic Surgery, Video-Assisted, business.industry, General Medicine, Length of Stay, Middle Aged, medicine.disease, Surgery, Chest tube, Settore MED/18 - Chirurgia Generale, Oncology, Cardiothoracic surgery, Chest Tubes, Anesthesia, Female, Neoplasm Recurrence, Local, medicine.symptom, business
Abstract

Awake single access video-assisted thoracic surgery with local anesthesia improves procedure tolerance, reduces postoperative stay and costs. Materials & methods: Local anesthesia was made with lidocaine and ropivacaine. We realize one 20 mm incision for the 'single-access', and two incisions for the '2-trocars technique'. Results: Mortality rate was 0% in both groups. Postoperative stay: 3dd ± 4 versus 4dd ± 5, mean operative time: 39 min versus 37 min (p < 0.05). Chest tube duration: 2dd ± 5 versus 3dd ± 6. Complications: 11/95 versus 10/79. Conclusion: Awake technique reduce postoperative hospital stay and chest drainage duration, similar complications and recurrence rate. The authors can say that 'awake single-access VATS' is an optimal diagnostic and therapeutic tool for the management of pleural effusions, but above extends surgical indication to high-risk patients. The history of video-assisted thoracic surgery (VATS) utilizing the local anesthesia and sedation is almost one century old with Jacobeus and Bethune (1). The authors started an 'awake single port VATS' program because they hypothesized that the use of just one access associated with local anesthesia might be feasible and could result in a better procedure acceptance, in a more rapid recovery, in a reduced procedure-related cost and in a more less invasive procedure. A single access associated with local anesthesia aims to improve procedure tolerance, shorten recovery and reduce costs. Materials & methods The authors retrospectively analyzed 174 patients with pleural effusion treated by awake technique or general anaesthesia. At admission, patients underwent complete laboratory assay, blood gases, chest roentgenograms, ectrocardiogram and eventually chest computed tomography (CT) scan and cardiological evaluation. An informed consent was obtained from all patients, including possibility of endotracheal intubation and thoracotomy. Premedication consisted in atropine 0.01 mg/kg and ondansetron 8 mg. Pain control and sedation were obtained by remifentanile (0.05-0.1 μg/kg/min) and midazolam (0.02-0.04 mg/kg). In the operating room, the patient was turned to a full lateral decubitus position and the table was flexed to widen the rib spaces on the operation side. A small antidecubitus mattress was placed below the dependent hemitorax to obtain a slight splitting of intercostal spaces without patient's discomforts. The position of the lonely trocar was usually defined with the help of utrasound (US). The using of US to choose the site of access was a rapid and safe method that helped to visualize the pleural effusion and that guided the operator to define the site of access, keeping away from some 'hazardous areas.' A line which included the plan of incision was drawn and the standard antiseptic procedure was performed. Local anesthesia was obtained with more...

Published
2015

48. Ultrasonography-guided central venous catheterisation in haematological patients with severe thrombocytopenia

Author

Mariasanta, Napolitano, Alessandra, Malato, Francesco, Raffaele, Manuela, Palazzolo, Giorgio, Lo Iacono, Roberto, Pinna, Girolamo, Geraci, Giuseppe, Modica, Giorgia, Saccullo, Sergio, Siragusa, Massimo, Cajozzo, Napolitano, M, Malato, A, Raffaele, F, Palazzolo, M, Iacono, GL, Pinna, R, Geraci, G, Modica, G, Saccullo, G, Siragusa, S, and Cajozzo, M. more...

Subjects
Adult, Aged, 80 and over, Male, Catheterization, Central Venous, Adolescent, Original Articles, Middle Aged, Severity of Illness Index, Thrombocytopenia, Settore MED/15 - Malattie Del Sangue, Settore MED/18 - Chirurgia Generale, central venous catheterisation, ultrasound, Seldinger technique, low platelet count, haematological malignancy, Humans, Female, Aged, Retrospective Studies, Ultrasonography
Abstract

BACKGROUND: Cannulation of the internal jugular vein (CVC) is a blind surface landmark-guided technique that could be potentially dangerous in patients with very low platelet counts. In such patients, ultrasonography (US)-guided CVC may be a valid approach. There is a lack of published data on the efficacy and safety of urgent US-guided CVC performed in haematological patients with severe thrombocytopenia. MATERIALS AND METHODS: We retrospectively studied the safety of urgent CVC procedures in haematological patients including those with severe thrombocytopenia (platelet count more...

Published
2013

49. Variation of POP concentrations in fresh-fallen snow and air on an Alpine glacier (Monte Rosa)

Author

Sara Villa, F. Raffaele, Antonio Finizio, Marco Vighi, Finizio, A, Villa, S, Raffaele, F, and Vighi, M

Subjects
Pollution, Health, Toxicology and Mutagenesis, media_common.quotation_subject, Atmospheric sciences, Snow, Hydrocarbons, Chlorinated, Ice Cover, Volatile organic compound, Pesticides, POPs, Mountain environment, air, snow, long range transport, media_common, Pollutant, chemistry.chemical_classification, Air Pollutants, Persistent organic pollutant, geography, geography.geographical_feature_category, Public Health, Environmental and Occupational Health, Glacier, General Medicine, Snowpack, Deposition (aerosol physics), Italy, chemistry, Environmental science, BIO/07 - ECOLOGIA, Volatilization, Environmental Monitoring
Abstract

To understand better the mechanisms ruling the fate of POPs (persistent organic pollutants) in cold environments, a field campaign sampling fresh-fallen snow and air on an Alpine glacier was carried out during Summer 2003. The concentrations of all analyzed chemicals in fresh-fallen snow show a sharp decrease over time, particularly for the more volatile POPs, confirming the rather limited literature evidence of a rapid decline of such substances from the snowpack and/or ice. Even if the results presented here are preliminary and should be confirmed by further studies, some evidence of the influence of a night/day cycle of temperature on POP deposition and revolatilization mechanisms has been highlighted. Finally, the role of cold condensation and long-range atmospheric transport in the contamination of higher altitudes in this Alpine system has been substantiated, particularly for OC pesticides. more...

Published
2006

50. Strained face during sleep in multiple system atrophy: not just a bad dream.

Author

Rosamaria L, Michela F, Emma B, Ana M, Bruno P, Philippe D, Bérangère D, Raffaele F, Monica P, Franck D, and Maria Livia F

Subjects
Humans, Retrospective Studies, Movement, Dreams, Parkinson Disease complications, Multiple System Atrophy complications, REM Sleep Behavior Disorder complications
Abstract

Study Objectives: Patients with Parkinson's disease and multiple system atrophy may be subject to sleep state dissociation. Motivated by the fortuitous observation of prominent facial muscle activity during video-polysomnography in patients with multiple system atrophy, we assessed facial motor activity and chin muscle tone during sleep in multiple system atrophy compared to Parkinson's disease and controls., Methods: A sleep expert blinded to pathology and sleep stage retrospectively analyzed facial activity in 62 video-polysomnography (11 multiple system atrophy, 38 Parkinson's disease, and 13 controls). Facial movements were classified into six categories: "Eyes closing/opening," "Eyebrows frowning," "Raising eyebrows," "Smiling," "Other mouth movements," and "Strained face," an expression involving both the superior and inferior parts of the face. Chin electromyography activity was quantified during Rapid Eye Movement (REM) and Non-Rapid Eye Movement (NREM) sleep using the atonia index, a validated algorithm., Results: Multiple system atrophy patients had an increased number of all facial movements compared to controls during NREM. "Strained face" was significantly more frequent in multiple system atrophy compared to Parkinson's disease, even after adjusting for the presence of REM sleep behavior disorder (RBD). Atonia index was lower in multiple system atrophy compared to controls and Parkinson's disease during REM and NREM sleep. This difference remained significant compared to Parkinson's disease in NREM sleep during N1 and N2 after adjusting for the presence of RBD., Conclusions: Facial movements during sleep are frequent in multiple system atrophy, "strained face" appears to be a hallmark of this condition. The presence of increased facial activity and elevated muscle tone during all stages of sleep in multiple system atrophy may be a manifestation of sleep state dissociation, reflecting more severe neurodegeneration., (© The Author(s) 2023. Published by Oxford University Press on behalf of Sleep Research Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.) more...

Published
2023
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