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2 results on '"Raf W.E.G. Reintjens"'

1. Key Green Engineering Research Areas for Sustainable Manufacturing: A Perspective from Pharmaceutical and Fine Chemicals Manufacturers

Author

Carl Franklin Indianapolis Bertsch, Peter Poechlauer, Phil Dell’Orco, Concepción Jiménez-González, Henk Noorman, Robert E. Hannah, Sandy Yee, Julie B. Manley, Bing-Shiou Yang, Andrew S. Wells, Quirinus B. Broxterman, Viviane Massonneau, David J. am Ende, James A Baird, and Raf W.E.G. Reintjens

Subjects
Green engineering, Engineering, Research areas, business.industry, Process (engineering), Sustainable manufacturing, Organic Chemistry, Chemical society, Engineering management, Key (cryptography), Pharmaceutical engineering, Physical and Theoretical Chemistry, business, Pharmaceutical industry
Abstract

In 2005, the American Chemical Society (ACS) Green Chemistry Institute (GCI) and global pharmaceutical companies established the ACS GCI Pharmaceutical Roundtable to encourage the integration of green chemistry and engineering into the pharmaceutical industry. The Roundtable developed a list of key research areas in green chemistry in 2007, which has served as a guide for focusing green chemistry research. Following that publication, the Roundtable companies have identified a list of the key green engineering research areas that is intended to be the required companion of the first list. This publication summarizes the process used to identify and agree on the top key green engineering research areas and describes these areas, highlighting their research challenges and opportunities for improvements from the perspective of the pharmaceutical industry.

Published
2011

2. Heterogeneously Catalyzed Continuous‐Flow Hydrogenation Using Segmented Flow in Capillary Columns

Author

Michiel T. Kreutzer, Martinus Mathilda Pieter Zieverink, Freek Kapteijn, Jasper J. W. Bakker, Raf W.E.G. Reintjens, and Jacob A. Moulijn

Subjects
pharmaceutical intermediates, Capillary action, Communication, Diffusion, Organic Chemistry, Flow (psychology), chemistry.chemical_element, flow reactions, palladium, Heterogeneous catalysis, Residence time (fluid dynamics), azides, Catalysis, Inorganic Chemistry, heterogeneous catalysis, chemistry, Chemical engineering, Physical and Theoretical Chemistry, Dispersion (chemistry), Palladium
Abstract

Segmented flow in standard GC capillary columns, with a heterogeneous Pd catalyst on the walls, gave rapid information about catalytic processes in them. The residence time and conversion was monitored visually, greatly simplifying bench-scale optimization. Examples show the benefits of the elimination of pore diffusion and axial dispersion. Further, we demonstrated how to quickly identify deactivating species in multistep synthesis without intermediate workup.

Published
2011

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