1. Optical coherence tomography to guide percutaneous coronary intervention of the left main coronary artery: the LEMON study
- Author
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Christophe Caussin, Nicolas Meneveau, Radwane Hakim, Mohamed Mehdi Boussaada, Thierry Lefèvre, Géraud Souteyrand, Matthieu Godin, Pascal Motreff, Guillaume Cayla, Nicolas Amabile, Frederic Casassus, Imane Bagdadi, Grégoire Rangé, Institut Mutualiste de Montsouris (IMM), Hôpitaux de Chartres [Chartres], CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand, Clinique St Hilaire ( Service de Cardiologie, Rouen), Marqueurs pronostiques et facteurs de régulations des pathologies cardiaques et vasculaires - UFC ( EA 3920) (PCVP / CARDIO), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Clinique Saint Augustin, Institut Cardiovasculaire Paris Sud, and Centre Jacques Cartier
- Subjects
medicine.medical_specialty ,medicine.medical_treatment ,MESH: Ultrasonography, Interventional ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,Angioplasty ,Intravascular ultrasound ,medicine ,Clinical endpoint ,MESH: Coronary Vessels ,030212 general & internal medicine ,cardiovascular diseases ,MESH: Coronary Artery Disease ,MESH: Treatment Outcome ,MESH: Aged ,MESH: Humans ,medicine.diagnostic_test ,business.industry ,Percutaneous coronary intervention ,Stent ,medicine.disease ,MESH: Pilot Projects ,MESH: Coronary Angiography ,MESH: Male ,MESH: Prospective Studies ,3. Good health ,Stenosis ,MESH: Stents ,MESH: Tomography, Optical Coherence ,surgical procedures, operative ,Conventional PCI ,Radiology ,Cardiology and Cardiovascular Medicine ,business ,MESH: Female ,MESH: Percutaneous Coronary Intervention ,TIMI - Abstract
International audience; Background: Intravascular ultrasound (IVUS)-guided PCI improves the prognosis of left main stem (LMS) PCI and is currently recommended by international guidelines. Although OCT resolution is greater than that of IVUS, this tool is not yet recommended in LMS angioplasty due to the absence of data.Aims: This pilot study aimed to analyse the feasibility, safety and impact of OCT-guided LMS PCI.Methods: This prospective, multicentre trial investigated whether patients might benefit from OCT-guided PCI for mid/distal LMS according to a pre-specified protocol. The primary endpoint was procedural success defined as follows: residual angiographic stenosis
- Published
- 2021