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372 results on '"Radujkovic, Aleksandar"'

2. Prognostic value of CPSS cytogenetic risk classification in patients with CMML after allogeneic hematopoietic cell transplantation: a retrospective multicenter study of the Chronic Malignancies Working Party of the EBMT

Author

Koenecke, Christian, Eikema, Dirk-Jan, Hazelaar, Sheree, Schroeder, Thomas, Potter, Victoria, Kröger, Nicolaus, Bornhäuser, Martin, Finke, Jürgen, Platzbecker, Uwe, Radujkovic, Aleksandar, Ganser, Arnold, Salmenniem, Urpu, Blaise, Didier, Kobbe, Guido, Meijer, Ellen, Friis, Lone, Maertens, Johan, Caballero, Dolores, Cornelissen, Jan J., Olivieri, Attilio, Gulsum, Ozet, Hayden, Patrick J., Onida, Francesco, Robin, Marie, and Yakoub-Agha, Ibrahim

Published
2022
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3. Role of allogeneic transplantation in chronic myelomonocytic leukemia: an international collaborative analysis

Author

Robin, Marie, de Wreede, Liesbeth C., Padron, Eric, Bakunina, Katerina, Fenaux, Pierre, Koster, Linda, Nazha, Aziz, Beelen, Dietrich W., Rampal, Raajit K., Sockel, Katja, Komrokji, Rami S., Gagelmann, Nico, Eikema, Dirk-Jan, Radujkovic, Aleksandar, Finke, Jürgen, Potter, Victoria, Killick, Sally B., Legrand, Faezeh, Solary, Eric, Broom, Angus, Garcia-Manero, Guillermo, Rizzoli, Vittorio, Hayden, Patrick, Patnaik, Mrinal M., Onida, Francesco, Yakoub-Agha, Ibrahim, and Itzykson, Raphael

Published
2022
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4. Prognostic value of a new clinically-based classification system in patients with CMML undergoing allogeneic HCT: a retrospective analysis of the EBMT-CMWP

Author

Onida, Francesco, Sbianchi, Giulia, Radujkovic, Aleksandar, Sockel, Katja, Kröger, Nicolaus, Sierra, Jorge, Socié, Gerard, Cornelissen, Jan, Poiré, Xavier, Raida, Luděk, Bourhis, Jean Henri, Finke, Jürgen, Passweg, Jakob, Salmenniemi, Urpu, Schouten, Harry C., Beguin, Yves, Martin, Sonja, Deconinck, Eric, Ganser, Arnold, Zver, Samo, Lioure, Bruno, Rohini, Radia, Koster, Linda, Hayden, Patrick, Iacobelli, Simona, Robin, Marie, and Yakoub-Agha, Ibrahim

Published
2022
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5. Influence of pretransplant inflammatory bowel disease on the outcome of allogeneic hematopoietic stem cell transplantation: a matched-pair analysis study from the Transplant Complications Working Party (TCWP) of the EBMT

Author

Peric, Zinaida, Peczynski, Christophe, Polge, Emmanuelle, Kröger, Nicolaus, Sengeloev, Henrik, Radujkovic, Aleksandar, Helbig, Grzegorz, Russell, Nigel, Bunjes, Donald, Socié, Gerard, Potter, Victoria, Beelen, Dietrich, Crawley, Charles, Bloor, Adrian, Finke, Jürgen, Schoemans, Helene, Penack, Olaf, Snowden, John A., Koenecke, Christian, and Basak, Grzegorz W.

Published
2021
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7. Outcomes following second allogeneic haematopoietic cell transplantation in patients with myelofibrosis: a retrospective study of the Chronic Malignancies Working Party of EBMT

Author

Nabergoj, Mitja, Mauff, Katya, Robin, Marie, Kröger, Nicolaus, Angelucci, Emanuele, Poiré, Xavier, Passweg, Jakob, Radujkovic, Aleksandar, Platzbecker, Uwe, Robinson, Stephen, Rambaldi, Alessandro, Petersen, Søren Lykke, Stölzel, Fridrich, Stelljes, Matthias, Ciceri, Fabio, Mayer, Jiri, Ladetto, Marco, de Wreede, Liesebeth C., Koster, Linda, Hayden, Patrick J., Czerw, Tomasz, Hernández-Boluda, Juan Carlos, McLornan, Donal, Chalandon, Yves, and Yakoub-Agha, Ibrahim

Published
2021
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9. A prognostic score including mutation profile and clinical features for patients with CMML undergoing stem cell transplantation

Author

Gagelmann, Nico, Badbaran, Anita, Beelen, Dietrich W., Salit, Rachel B., Stölzel, Friedrich, Rautenberg, Christina, Becker, Heiko, Radujkovic, Aleksandar, Panagiota, Victoria, Bogdanov, Rashit, Christopeit, Maximilian, Park, Yong, Nibourel, Olivier, Luft, Thomas, Koldehoff, Michael, Corsten, Maarten, Heuser, Michael, Finke, Jürgen, Kobbe, Guido, Platzbecker, Uwe, Robin, Marie, Scott, Bart L., and Kröger, Nicolaus

Published
2021
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11. CAR T cells or allogeneic transplantation as standard of care for advanced large B-cell lymphoma: an intent-to-treat comparison

Author

Dreger, Peter, Dietrich, Sascha, Schubert, Maria-Luisa, Selberg, Lorenz, Bondong, Andrea, Wegner, Mandy, Stadtherr, Peter, Kimmich, Christoph, Kosely, Florentina, Schmitt, Anita, Pavel, Petra, Liebers, Nora, Luft, Thomas, Hegenbart, Ute, Radujkovic, Aleksandar, Ho, Anthony Dick, Müller-Tidow, Carsten, and Schmitt, Michael

Published
2020
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16. Myeloablative and Reduced-Intensity Conditioned Allogeneic Hematopoietic Stem Cell Transplantation in Myelofibrosis: A Retrospective Study by the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation

Author

McLornan, Donal, Szydlo, Richard, Koster, Linda, Chalandon, Yves, Robin, Marie, Wolschke, Christine, Beelen, Dietrich, Socié, Gerard, Bornhäuser, Martin, Angelucci, Emanuele, Niederwieser, Dietger, Gerbitz, Arnim, Finke, Jürgen, Vitek, Antonin, Itälä-Remes, Maija, Radujkovic, Aleksandar, Kanz, Lothar, Potter, Victoria, Chevallier, Patrice, Stelljes, Matthias, Petersen, Eefke, Robinson, Stephen, Poiré, Xavier, Klyuchnikov, Evgeny, Hernández-Boluda, Juan Carlos, Czerw, Tomasz, Hayden, Patrick, Kröger, Nicolaus, and Yakoub-Agha, Ibrahim

Published
2019
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17. Allogeneic Stem Cell Transplantation for Blast Crisis Chronic Myeloid Leukemia in the Era of Tyrosine Kinase Inhibitors: A Retrospective Study by the EBMT Chronic Malignancies Working Party

Author

Radujkovic, Aleksandar, Dietrich, Sascha, Blok, Henric-Jan, Nagler, Arnon, Ayuk, Francis, Finke, Jürgen, Tischer, Johanna, Mayer, Jiri, Koc, Yener, Sorà, Federica, Passweg, Jakob, Byrne, Jenny L., Jindra, Pavel, Veelken, Joan Hendrik, Socié, Gerard, Maertens, Johan, Schaap, Nicolaas, Stadler, Michael, Itälä-Remes, Maija, Tholouli, Eleni, Arat, Mutlu, Rocha, Vanderson, Ljungman, Per, Yakoub-Agha, Ibrahim, Kröger, Nicolaus, and Chalandon, Yves

Published
2019
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18. Outcomes of CMML patients undergoing allo‐HCT are significantly worse compared to MDS—a study of the CMWP of the EBMT

Author

Rovó, Alicia, primary, Gras, Luuk, additional, Piepenbroek, Brian, additional, Kröger, Nicolaus, additional, Reinhardt, H. Christian, additional, Radujkovic, Aleksandar, additional, Blaise, Didier, additional, Kobbe, Guido, additional, Niityvuopio, Riitta, additional, Platzbecker, Uwe, additional, Sockel, Katja, additional, Hunault‐Berger, Mathilde, additional, Cornelissen, J. J., additional, Forcade, Edouard, additional, Bourhis, Jean Henri, additional, Chalandon, Yves, additional, Kinsella, Francesca, additional, Nguyen‐Quoc, Stéphanie, additional, Maertens, Johan, additional, Elmaagacli, Ahmet, additional, Mordini, Nicola, additional, Hayden, Patrick, additional, Raj, Kavita, additional, Drozd‐Sokolowska, Joanna, additional, de Wreede, Liesbeth C., additional, McLornan, Donal P., additional, Robin, Marie, additional, Yakoub‐Agha, Ibrahim, additional, and Onida, Francesco, additional

Published
2023
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19. Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations

Author

Pellagatti, Andrea, Armstrong, Richard N., Steeples, Violetta, Sharma, Eshita, Repapi, Emmanouela, Singh, Shalini, Sanchi, Andrea, Radujkovic, Aleksandar, Horn, Patrick, Dolatshad, Hamid, Roy, Swagata, Broxholme, John, Lockstone, Helen, Taylor, Stephen, Giagounidis, Aristoteles, Vyas, Paresh, Schuh, Anna, Hamblin, Angela, Papaemmanuil, Elli, Killick, Sally, Malcovati, Luca, Hennrich, Marco L., Gavin, Anne-Claude, Ho, Anthony D., Luft, Thomas, Hellström-Lindberg, Eva, Cazzola, Mario, Smith, Christopher W.J., Smith, Stephen, and Boultwood, Jacqueline

Published
2018
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21. Haploidentical transplant in patients with myelodysplastic syndrome

Author

Robin, Marie, Porcher, Raphael, Ciceri, Fabio, van Lint, Maria Teresa, Santarone, Stella, Ehninger, Gerhard, Blaise, Didier, Güllbas, Zafer, Gonzáles Muñiz, Soledad, Michallet, Mauricette, Velardi, Andrea, Koster, Linda, Maertens, Johan, Sierra, Jorge, Selleslag, Dominik, Radujkovic, Aleksandar, Díez-Martin, José L., Kanz, Lothar, Arroyo, Concepcion Herrera, Niederwieser, Dietger, Huang, He, McDonald, Andrew, de Witte, Theo, Koc, Yener, and Kröger, Nicolaus

Published
2017
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24. Outcomes of CMML patients undergoing allo‐HCT are significantly worse compared to MDS—a study of the CMWP of the EBMT.

Author

Rovó, Alicia, Gras, Luuk, Piepenbroek, Brian, Kröger, Nicolaus, Reinhardt, H. Christian, Radujkovic, Aleksandar, Blaise, Didier, Kobbe, Guido, Niityvuopio, Riitta, Platzbecker, Uwe, Sockel, Katja, Hunault‐Berger, Mathilde, Cornelissen, J. J., Forcade, Edouard, Bourhis, Jean Henri, Chalandon, Yves, Kinsella, Francesca, Nguyen‐Quoc, Stéphanie, Maertens, Johan, and Elmaagacli, Ahmet

Published
2024
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29. Donor Lymphocyte Infusions for Chronic Myeloid Leukemia Relapsing after Allogeneic Stem Cell Transplantation: May We Predict Graft-versus-Leukemia Without Graft-versus-Host Disease?

Author

Radujkovic, Aleksandar, Guglielmi, Cesare, Bergantini, Stefania, Iacobelli, Simona, van Biezen, Anja, Milojkovic, Dragana, Gratwohl, Alois, Schattenberg, Antonius V.M.B., Verdonck, Leo F., Niederwieser, Dietger W., de Witte, Theo, Kröger, Nicolaus, and Olavarria, Eduardo

Published
2015
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30. Outcomes after allogeneic hematopoietic cell transplant in patients diagnosed with blast phase of myeloproliferative neoplasms: A retrospective study from the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation

Author

Ortí, Guillermo, primary, Gras, Luuk, additional, Zinger, Nienke, additional, Finazzi, Maria Chiara, additional, Sockel, Katja, additional, Robin, Marie, additional, Forcade, Edouard, additional, Avenoso, Daniele, additional, Kröger, Nicolaus, additional, Finke, Jürgen, additional, Radujkovic, Aleksandar, additional, Hunault‐Berger, Mathilde, additional, Schroyens, Wilfried, additional, Zuckerman, Tsila, additional, Bourhis, Jean Henri, additional, Chalandon, Yves, additional, Bloor, Adrian, additional, Schots, Rik, additional, de Wreede, Liesbeth C., additional, Drozd‐Sokolowska, Joana, additional, Raj, Kavita, additional, Polverelli, Nicola, additional, Czerw, Tomasz, additional, Hernández‐Boluda, Juan Carlos, additional, McLornan, Donal, additional, and Yakoub‐Agha, Ibrahim, additional

Published
2023
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31. Endothelial cell dysfunction: a key determinant for the outcome of allogeneic stem cell transplantation

Author

Luft, Thomas, Dreger, Peter, and Radujkovic, Aleksandar

Subjects
Oncology, medicine.medical_specialty, Transplantation Conditioning, Thrombotic microangiopathy, Endothelium, medicine.medical_treatment, Graft vs Host Disease, Review Article, Hematopoietic stem cell transplantation, 03 medical and health sciences, Medical research, 0302 clinical medicine, Internal medicine, Humans, Transplantation, Homologous, Medicine, Endothelial dysfunction, Host disease, Retrospective Studies, Transplantation, business.industry, Hematopoietic Stem Cell Transplantation, Endothelial Cells, Hematology, medicine.disease, Endothelial stem cell, Biological sciences, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Stem cell, business, Stem Cell Transplantation, 030215 immunology
Abstract

Allogeneic hematopoietic stem cell transplantation (alloSCT) carries the promise of cure for many malignant and non-malignant diseases of the lympho-hematopoietic system. Although outcome has improved considerably since the pioneering Seattle achievements more than 5 decades ago, non-relapse mortality (NRM) remains a major burden of alloSCT. There is increasing evidence that endothelial dysfunction is involved in many of the life-threatening complications of alloSCT, such as sinusoidal obstruction syndrome/venoocclusive disease, transplant-associated thrombotic microangiopathy, and refractory acute graft-versus host disease. This review delineates the role of the endothelium in severe complications after alloSCT and describes the current status of search for biomarkers predicting endothelial complications, including markers of endothelial vulnerability and markers of endothelial injury. Finally, implications of our current understanding of transplant-associated endothelial pathology for prevention and management of complications after alloSCT are discussed.

Published
2021
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34. Outcomes of allogeneic haematopoietic cell transplantation for chronic neutrophilic leukaemia: A combined CIBMTR / CMWP of EBMT analysis

Author

Dholaria, Bhagirathbhai, primary, Radujkovic, Aleksandar, additional, Estrada‐Merly, Noel, additional, Sirait, Tiarlan, additional, Kim, Soyoung, additional, Hernández‐Boluda, Juan Carlos, additional, Czerw, Tomasz, additional, Hayden, Patrick J., additional, Kansagra, Ankit, additional, Ho, Vincent T., additional, Nishihori, Taiga, additional, Shaughnessy, Paul, additional, Scott, Bart, additional, Nakamura, Ryotaro, additional, Oran, Betul, additional, Kharfan‐Dabaja, Mohamed, additional, Savani, Bipin N., additional, McLornan, Donal, additional, Yakoub‐Agha, Ibrahim, additional, and Saber, Wael, additional

Published
2022
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35. Prognostic value of CPSS cytogenetic risk classification in patients with CMML after allogeneic hematopoietic cell transplantation:a retrospective multicenter study of the Chronic Malignancies Working Party of the EBMT

Author

Koenecke, Christian, Eikema, Dirk Jan, Hazelaar, Sheree, Schroeder, Thomas, Potter, Victoria, Kröger, Nicolaus, Bornhäuser, Martin, Finke, Jürgen, Platzbecker, Uwe, Radujkovic, Aleksandar, Ganser, Arnold, Salmenniem, Urpu, Blaise, Didier, Kobbe, Guido, Meijer, Ellen, Friis, Lone, Maertens, Johan, Caballero, Dolores, Cornelissen, Jan J., Olivieri, Attilio, Gulsum, Ozet, Hayden, Patrick J., Onida, Francesco, Robin, Marie, Yakoub-Agha, Ibrahim, Koenecke, Christian, Eikema, Dirk Jan, Hazelaar, Sheree, Schroeder, Thomas, Potter, Victoria, Kröger, Nicolaus, Bornhäuser, Martin, Finke, Jürgen, Platzbecker, Uwe, Radujkovic, Aleksandar, Ganser, Arnold, Salmenniem, Urpu, Blaise, Didier, Kobbe, Guido, Meijer, Ellen, Friis, Lone, Maertens, Johan, Caballero, Dolores, Cornelissen, Jan J., Olivieri, Attilio, Gulsum, Ozet, Hayden, Patrick J., Onida, Francesco, Robin, Marie, and Yakoub-Agha, Ibrahim

Published
2022

36. Response to Vaccination with Sars-CoV2 Vaccines in Patients Post Allogeneic Hematopoietic Cell Transplantation

Author

Pabst, Caroline, primary, Liebers, Nora, additional, Schubert, Maria-Luisa, additional, Simons, Laura, additional, Bondong, Andrea, additional, Wegner, Mandy, additional, Dietrich, Sascha, additional, Hegenbart, Ute, additional, Schönland, Stefan, additional, Radujkovic, Aleksandar, additional, Schmitt, Michael, additional, Schnitzler, Paul, additional, Müller-Tidow, Carsten, additional, Dreger, Peter, additional, and Luft, Thomas, additional

Published
2022
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38. Humoral Responses and Chronic GVHD Exacerbation after COVID-19 Vaccination Post Allogeneic Stem Cell Transplantation

Author

Pabst, Caroline, primary, Benning, Louise, additional, Liebers, Nora, additional, Janssen, Maike, additional, Caille, Leandra, additional, Speer, Claudius, additional, He, Lixiazi, additional, Schubert, Maria-Luisa, additional, Simons, Laura, additional, Hegenbart, Ute, additional, Schönland, Stefan, additional, Radujkovic, Aleksandar, additional, Schmitt, Michael, additional, Schnitzler, Paul, additional, Müller-Tidow, Carsten, additional, Dietrich, Sascha, additional, Dreger, Peter, additional, and Luft, Thomas, additional

Published
2022
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40. Statin‐based endothelial prophylaxis and outcome after allogeneic stem cell transplantation.

Author

Pabst, Caroline, Schreck, Nicholas, Benner, Axel, Hegenbart, Ute, Schönland, Stefan, Radujkovic, Aleksandar, Schmitt, Michael, Müller‐Tidow, Carsten, Orsatti, Laura, Dreger, Peter, and Luft, Thomas

Subjects
STEM cell transplantation, HEMATOPOIETIC stem cell transplantation, ENDOTHELIUM diseases, INDOLEAMINE 2,3-dioxygenase, ADVERSE health care events, ENZYME metabolism
Abstract

Background: Allogeneic haematopoietic stem cell transplantation (alloSCT) often remains the only curative therapy for hematologic malignancies. Although the management of transplant‐associated adverse events considerably improved over the last decades, nonrelapse mortality (NRM) remains a challenge, and endothelial dysfunction was identified as a major contributor to NRM. Methods: Statin‐based endothelial prophylaxis (SEP) has been implemented in the standard of care in our transplant centre to reduce NRM caused by endothelial injury. Here, we retrospectively analysed the impact of SEP on clinical outcome in a cohort of 347 alloSCT patients. Results: SEP (n = 209) was associated with significantly reduced NRM (hazard ratio 0.61, 95% CI 0.38–0.96) and better overall survival (OS) after acute graft‐versus‐host disease (HR 0.59, 95% CI 0.37–0.93). Subgroup analyses showed that the NRM benefit was mainly found in patients with an intermediate endothelial activation and stress index (EASIX), while relapse risk was not affected. On day 100 post‐alloSCT, patients receiving SEP had significantly higher levels of the rate‐limiting enzyme of tryptophan metabolism, indoleamine 2,3‐dioxygenase (IDO), higher kynurenine to tryptophan ratios as a proxy of IDO activity and tended to have lower levels of the endothelial injury marker ST2 (p =.055). No significant differences in interferon‐gamma or IL18 levels were observed. These biomarker signatures suggest that the beneficial effects of SEP might be mediated by both endothelial protection and immunomodulation. Conclusions: Together, these data suggest that SEP improves NRM and OS post‐alloSCT in particular in patients with intermediate endothelial risk and provide first mechanistic clues about its potential mode of action. [ABSTRACT FROM AUTHOR]

Published
2023
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44. Submyeloablative total body irradiation‐based conditioning and allogeneic stem cell transplantation in high‐risk myeloma with early progression after up‐front autologous transplantation

Author

Mai, Elias K., primary, Schmitt, Thomas, additional, Radujkovic, Aleksandar, additional, König, Laila, additional, Goldschmidt, Hartmut, additional, Ho, Anthony D., additional, Luft, Thomas, additional, Müller‐Tidow, Carsten, additional, Dreger, Peter, additional, Hegenbart, Ute, additional, and Schönland, Stefan O., additional

Published
2021
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49. Additional file 2 of Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COVID-19 disease severity and indicator of the need for mechanical ventilation, ARDS and mortality

Author

Lim, Adeline, Radujkovic, Aleksandar, Weigand, Markus A., and Merle, Uta

Abstract

Additional file 2. sRAGE levels vary with disease severity. sRAGE values were subject to natural log transformation (sRAGE Ln) due to highly skewed distribution. sRAGE increases as qSOFA score increases. The increase in sRAGE level is significant when qSOFA score increases from 0 to 1, p0.5 mg/L [U(Nlow D-Dimer=35, Nhigh D-Dimer=77)=2120, z=4.85, p

Published
2021
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50. Additional file 3 of Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COVID-19 disease severity and indicator of the need for mechanical ventilation, ARDS and mortality

Author

Lim, Adeline, Radujkovic, Aleksandar, Weigand, Markus A., and Merle, Uta

Abstract

Additional file 3. Comparison of ROC curves using cut-offs for predicting mechanical ventilation. Top: ROC curves for sRAGE, CRP, IL-6, D-Dimer and in their combination with sRAGE using cut-offs predicting MV for inpatients. Bottom: AUC with 95% CI and p value for all variables predicting MV for inpatients. A combination of sRAGE and IL-6 is the best parameter at predicting MV. AUC: Area under the curve. ROC: receiver operating curve. sRAGE: soluble receptor for advanced glycation end products. CRP: C-reactive protein. IL-6: Interleukin-6. CI: confidence interval. MV: mechanical ventilation.

Published
2021
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