1. A new era of high-resolution CT diagnostics of the lung: improved image quality, detailed morphology, and reduced radiation dose with high-resolution photon-counting CT of the lungs compared to high-resolution energy-integrated CT.
- Author
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Aurumskjöld, Marie-Louise, Sjunnesson, Lotta, Pistea, Adrian, Ásbjörnsson, Gylfi, Wellman, Fredrik, and Bozovic, Gracijela
- Subjects
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INTERSTITIAL lung diseases , *COMPUTED tomography , *BODY mass index , *RADIATION doses , *LUNGS - Abstract
Background: High-resolution computed tomography (HRCT) is dependent on detailed morphology in diagnostic assessment of interstitial lung diseases. Photon-counting CT (PCCT) enables improved resolution while reducing radiation. Purpose: To compare if the image quality, detailed morphology, and radiation dose in HRCT of the lung improves with PCCT compared to energy-integrated CT (EICT). Material and Methods: HRCT with PCCT in patients with body mass index (BMI) from normal to obese, previously examined with different EICT were included. They were evaluated in a five-step scale for image quality according to Quality Criteria for CT (Diagnostic Requirement of the ImPACT group-European standardization). In addition, ground-glass opacities, bronchiectasis, emphysema, nodules, and subpleural detailed morphology (≤1 cm from the pleural border) were evaluated by three independent thoracic and/or pediatric radiologists. Visual grading characteristics (VGC) were used for comparison of image quality and detailed morphology and Fleiss kappa for intra-observer variability. Dose-length product (DLP) and CT dose index-volume (CTDIvol) were collected to calculate effective radiation dose. Results: HRCT with PCCT in 52 women and 48 men (mean age=67.2 ± 13.6 years; age range=27–87 years; BMI=26.9 kg/m2; range=18.6–45 kg/m2) previously examined with EICT (mean age=65.3 ± 13.6 years; age range=27–85 years; BMI=27 kg/m2; range=18.9–45 kg/m2) were included. There were significant differences in image quality for all entities in favor of PCCT. The radiation dose was reduced with PCCT by 47% in all, particularly pronounced in obese with 48.5%. Conclusion: Image quality, detailed morphology, and radiation dose, particularly in obese patients, were significantly improved in HRCT with PCCT compared to conventional EICT. The new technique enables visualization of subpleural structures. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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