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Objectives: This study investigates the relationship between the total volume of oral tongue cancer pre-operatively and the RFFF volume post-operatively. Materials and methods: A total of 52 DICOM imaging datasets (CT or MRI) of 26 patients were included in this study. The volume of the desired structure was quantified using semi-automatic segmentation using the software ITK-SNAP. All extracted measurements were validated by two further clinicians at separate instances. Results: The variation of MeanVolTu can be predicted by MeanVolFlap moderately reliable with 59.1% confidence (R-Qua: 0.591). ANOVA Testing to represent how well the regression line fits the data, resulted in the overall regression model being statistically significant in predicting the MeanVolTu (p < 0.001). The flap volume may be predicted using the following algorithm: MeanVolFlap0 = 3241,633 + 1, 322 * MeanVolTu. Conclusion: The results of this study show positive correlation between tumor volume and flap volume, highlighting the significance of efficient flap planning with increasing tumor volume. A larger extraction volume of the radial forearm free flap from the donor site compromises the forearm more, thus increasing the probability of post-operative complications. Clinical relevance: Radial forearm free flap design in accordance with its corresponding 3D tumor volume. [ABSTRACT FROM AUTHOR]

Background: Ultrasound shear wave elastography (SWE) noninvasively measures the stiffness of tissue by producing and measuring tissue deformation. Scar formation, a crucial aspect of wound healing, can lead to functional and aesthetic complications when pathological. While SWE has shown promise in dermatological evaluations, its role in surgical scar assessment remains underestimated. Our study aims to investigate SWE in evaluating surgical scars at the donor site after forearm free flap surgery in transgender patients. Methods: After radial forearm free flap harvesting, the donor site was grafted with a split-thickness skin graft with or without interposition of Matriderm. Eleven patients were evaluated more than one year after surgery, using SWE alongside scar characteristics, sensory outcomes, and patient satisfaction surveys. Results: Our study revealed no significant difference in stiffness (p > 0.15), pigmentation (p = 0.32), or erythema (p = 0.06) between operated and non-operated sides. The interposition of Matriderm did not influence the stiffness. Patients significantly (p < 0.0001) reported a loss of discrimination. Patients' subjective scar evaluation appeared in line with our quantitative and objective results. Conclusions: This study contributes to the evolving understanding of SWE's role in scar assessment, highlighting its feasibility in evaluating surgical scars. However, continued research efforts are necessary to establish SWE as a reliable and objective method for surgical scar evaluation and management. [ABSTRACT FROM AUTHOR]

Reconstruction post-orbital exenteration serves the dual purpose of expediting healing, laying the groundwork for cosmetic restoration, and minimising complications such as orbitosinusal fistulae. The aim of this study was to introduce a modified "Ice cream cone" (ICC) design of the Radial Forearm Free Flap (RFFF) technique used for reconstruction of orbital exenteration cavity, along with the oncological, functional, and aesthetic outcomes. The authors conducted a retrospective study between January 2005 and December 2020. Inclusion criteria encompassed patients treated for orbitosinusal malignancies undergoing exenteration with subsequent ICC design of RFFF reconstruction. Twenty-two patients underwent exenteration with the ICC design of RFFF. At the follow-up conclusion, 65% of patients regularly used orbital prosthesis. The average waiting time until the prosthesis was 10 months. Quality of life questionnaires yielded average RFFF POSAS scores of 23.5 (SD 13,6), cervical POSAS scores of 8 (SD 13,2), and orbital cavity rehabilitation scores of 5.9 (SD: 3,32). ICC design of RFFF is a reliable technique. It can be proposed in cases of extended exenteration with a high risk of cerebrospinal fluid (CSF) but more generally in cases of total exenteration. This technique facilitates optimal postoperative wound healing and accommodates early radiotherapy. Importantly, the bowl-shaped aspect of the orbital socket supports effective prosthetic rehabilitation for patients opting for orbital prosthesis post-surgery. [ABSTRACT FROM AUTHOR]

Case: A 51-year-old woman, who had previously undergone C5-C7 anterior cervical discectomy and fusion, presented with symptomatic hardware failure and subsequently underwent instrumentation removal. Her postoperative course was complicated by an esophageal perforation. Despite initial repair using a rotational flap, the leak persisted, prompting esophageal reconstruction with a radial forearm free flap (RFFF). Conclusion: Persistent esophageal perforation is exceedingly rare and difficult to treat. This report discusses the surgical technique for RFFF, an excellent option for revising failed sternocleidomastoid rotational flaps. The decision between rotational repair and free flap reconstruction depends on factors such as defect size, vascularization, wound condition, and donor site morbidity. [ABSTRACT FROM AUTHOR]

Reconstruction of pharyngoesophageal defects following total laryngectomy poses a significant challenge. The goals of reconstruction are to provide alimentary tract continuity and to restore speech and swallowing functions. Patients with radiotherapy recurrent disease often have unfavourable tissue for healing with a high incidence of pharyngocutaneous fistula. We discuss utilisation of a double skin paddle radial forearm free flap for pharyngoesophageal reconstruction as well as a cutaneous skin defect.A 53-year-old female was referred to our department for reconstruction of her total laryngectomy defect secondary to radio-recurrent right laryngeal squamous cell carcinoma with extra-laryngeal spread.Reconstruction planning was challenging as the patient was an obese, heavy smoker with significantly irradiated neck skin. A tubed radial artery forearm free flap was planned for pharyngoesophageal reconstruction however due to the extent of radiotherapy skin damage; primary closure of the neck defect was not possible. The flap was modified into a double paddle design to reconstruct the pharyngoesophageal defect, with the second skin paddle folded over to reconstruct the cutaneous defect.Multiple reconstructive options have been described in the literature for primary laryngectomy defects. Complex patients with recurrence particularly after neoadjuvant treatment are often poor candidates for reconstruction with poor tissue viability. Providing sufficient and adequate soft-tissue coverage is essential to minimise complications. We have described an intra-operatively planned, novel technique of reconstruction. Pre-operative anticipation may assist in addressing complexities encountered particularly in settings of hostile native skin.

Background: It remains unclear whether a tubed fasciocutaneous or jejunal free flap (FCFF and JFF) is preferable for reconstruction of circumferential pharyngolaryngoesophageal defects. Methods: All consecutive patients with circumferential pharyngolaryngoesophageal defects reconstructed with an FCFF or JFF between 2000 and 2022 were included. Outcomes of interest were rates of fistulas, strictures, and donor‐site complications. Results: In total, 112 patients were included (35 FCFFs and 77 JFFs). Fistula and stricture rates were significantly lower following JFF compared to FCFF reconstructions, with 12% versus 34% (p = 0.008) and 29% versus 49% (p = 0.04), respectively. Severe donor‐site complications leading to surgical intervention or ICU admittance only occurred after JFF reconstructions (18%, p = 0.007). Conclusions: The high fistula and stricture rates in FCFF reconstructions and the rate of severe abdominal complications in JFF reconstructions illustrate inherent procedure‐specific advantages and disadvantages. Relative pros and cons should be carefully weighed when tailoring treatments to the individual needs of patients. [ABSTRACT FROM AUTHOR]

Introductıon: Columellar subunit reconstruction is described as one the most challenging area in the literature. Radial forearm free flap (RFFF) can easily provide the reconstruction of columella and neighbouring regions with different styles of designs and different types of tissues included if needed. Methods: Patients who have large composite defects in the septocolumellar region and have been reconstructed with RFFF between 2018-2021 were included in the study. Patients’ age, gender, etiology of septocolumellar defect, anatomical deficiencies on nose, flap sizes and designs, cartilage donor site, recipient vessels, flap donor site repair methods, time of hospital stay, and complications were investigated. Results: Six patients, comprising five males and one female with an average age of 50.8 years, were evaluated. The etiologies were congenital agenesis in one patient, trauma in two patients, and tumors in three patients. Adipofascial radial forearm free flaps (RFFF) were utilized in two patients, with primary closure of the donor sites. To prevent excessive skin thickness in septal mucosal reconstruction, only adipofascial flaps were employed. The facial artery and vein served as the recipient vessels in all cases, with the pedicle tunneled from the nasal region to the submandibular region. The average flap size was 5.08 x 4.66 cm. Septal cartilage was used to create the cartilage framework in two cases, while costal cartilage was used in the remaining cases. The mean operation time was 6.6 hours, the average ICU stay was 16.3 hours, and the mean hospitalization duration was 6.5 days. Complications included scar spread and synechia at the flap donor site in two different patients. Conclusion: Using the facial artery and vein for recipient vessels makes the new skin scarring away from midface area. RFFF provides an excellent option for optimal septocolumellar reconstruction deriving from a variety of etiologies with the disadvantage of sacrificing a main artery in upper extremity. [ABSTRACT FROM AUTHOR]

Objective: Radial Forearm Free flap (RFFF) is widely used in head and neck reconstruction, yet its donor site defect remains a significant drawback. The Medial Sural Artery Perforator Free Flap (MSAPFF) is considered an alternative flap to RFFF. This study aims to comprehensively analyze their characteristics, outcomes, and their impact on patient quality of life. Methods: All patients who underwent oral cavity reconstruction using RFFF and MSAPFF between February 2017 and April 2023 were included in this study. Flap characteristics, outcomes and post-operative complications were recorded and compared. Subjective donor site morbidity, aesthetic and functional results, and quality of life were also analyzed. Results: The study included 76 patients: 37 underwent reconstruction with RFFF, and 39 with MSAPFF. There was no significance difference between the RFFF and MSAPFF regarding the success rate (97.2% vs 97.4%), flap size (4.8 × 8.8 cm2 vs 5 × 9.8 cm2), hospital of stay (15.5 days vs 13.5 days) and recipient site complications (P > 0.05). However, MSAPFF showed larger flap thickness (P = 0.001), smaller arterial caliber (P = 0.008), shorter pedicle length (P = 0.001), and longer harvesting time (P < 0.001). No significant difference was observed between the pre-and postoperative ranges of wrist and ankle movements or in recipient site complications. MSAPFF showed a significant difference in donor site morbidity (P < 0.05). Conclusion: The MSAPFF is an excellent alternative to the RFFF for repairing oral cavity defects, with additional advantage of a well-hidden scar on the posterior calf, a larger flap thickness, accepted pedicle length and arterial caliber. However, one should consider the harvesting time and surgical skills required in comparison to the RFFF. Clinical relevance: The study highlights the importance of the MSAPFF as an alternative option for RFFF with less donor site morbidity and high success rate in oral cavity reconstruction and improved patient Quality of life after ablative surgery. [ABSTRACT FROM AUTHOR]

[Display omitted] The radial forearm free flap (RFFF) is commonly used in the reconstruction of oral cancer patients. Traditional RFFF (TRFFF) techniques, which often require a secondary donor site to repair the forearm defect, may result in a scar extending to the dorsal hand. This can lead to significant functional and aesthetic concerns in the forearm. We designed a modified RFFF (MRFFF) that incorporates a glasses-shaped flap and features deep venous drainage. To evaluate its effectiveness we conducted a retrospective chart review of 105 patients with oral squamous cell carcinoma who underwent reconstructive surgery between 2018 and 2022. These patients were treated either with a TRFFF (n = 60) or the newly developed MRFFF (n = 45). Our inclusion criteria, guided by preliminary surgical experience prior to initiating the study, stipulated that single oral defects should be no larger than 6 × 6 cm2, and adjacent double defects no larger than 3 × 6 cm2. Flap size, pedicle length, harvesting duration, and anastomosis during the surgical procedure were compared between the two techniques. Preoperative and postoperative oral function, recurrence, mortality, and dorsal scarring were recorded. One-week, one-month, and six-month postoperative subjective aesthetics assessments, and self-reported postoperative donor hand function, were measured using the Michigan hand questionnaire (MHQ). There were no significant differences between the groups in terms of flap size, pedicle length, harvesting time, anastomosis time, postoperative oral function, recurrence, and mortality. However, patients with a MRFFF did not require a second donor graft site and did not have scars extending to the dorsal forearm. They also had significantly improved postoperative aesthetic outcomes (1 week: 70.6%, 1 month: 62.2%) and donor hand function (1 week: 54.6%, 1 month: 40.4%) compared with the TRFFF group (p < 0.001). The MRFFF eliminates the need for secondary donor sites and improves primary donor site outcomes. It is versatile and can be employed for either single or composite oral defects. Through extensive case studies, we have defined its specific scope: it is suitable for single defects measuring no more than 6 × 6 cm2, or for composite defects no larger than 3 × 6 cm2. Furthermore, it does not compromise the functional recovery of the recipient site, and should be widely adopted for all qualifying patients. [ABSTRACT FROM AUTHOR]

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Abstract Background The radial forearm free flap (RFFF) serves as a workhorse for a variety of reconstructions. Although there are a variety of surgical techniques for donor site closure after RFFF raising, the most common techniques are closure using a split-thickness skin graft (STSG) or a full-thickness skin graft (FTSG). The closure can result in wound complications and function and aesthetic compromise of the forearm and hand. The aim of the planned systematic review and meta-analysis is to compare the wound-related, function-related and aesthetics-related outcome associated with full-thickness skin grafts (FTSG) and split-thickness skin grafts (STSG) in radial forearm free flap (RFFF) donor site closure. Methods A systematic review and meta-analysis will be conducted. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines will be followed. Electronic databases and platforms (PubMed, Embase, Scopus, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), China National Knowledge Infrastructure (CNKI)) and clinical trial registries (ClinicalTrials.gov, the German Clinical Trials Register, the ISRCTN registry, the International Clinical Trials Registry Platform) will be searched using predefined search terms until 15 January 2024. A rerun of the search will be carried out within 12 months before publication of the review. Eligible studies should report on the occurrence of donor site complications after raising an RFFF and closure of the defect. Included closure techniques are techniques that use full-thickness skin grafts and split-thickness skin grafts. Excluded techniques for closure are primary wound closure without the use of skin graft. Outcomes are considered wound-, functional-, and aesthetics-related. Studies that will be included are randomized controlled trials (RCTs) and prospective and retrospective comparative cohort studies. Case-control studies, studies without a control group, animal studies and cadaveric studies will be excluded. Screening will be performed in a blinded fashion by two reviewers per study. A third reviewer resolves discrepancies. The risk of bias in the original studies will be assessed using the ROBINS-I and RoB 2 tools. Data synthesis will be done using Review Manager (RevMan) 5.4.1. If appropriate, a meta-analysis will be conducted. Between-study variability will be assessed using the I2 index. If necessary, R will be used. The quality of evidence for outcomes will eventually be assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Discussion This study's findings may help us understand both closure techniques' complication rates and may have important implications for developing future guidelines for RFFF donor site management. If available data is limited and several questions remain unanswered, additional comparative studies will be needed. Systematic review registration The protocol was developed in line with the PRISMA-P extension for protocols and was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on 17 September 2023 (registration number CRD42023351903).

Background: The radial forearm free flap (RFFF) serves as a workhorse for a variety of reconstructions. Although there are a variety of surgical techniques for donor site closure after RFFF raising, the most common techniques are closure using a split-thickness skin graft (STSG) or a full-thickness skin graft (FTSG). The closure can result in wound complications and function and aesthetic compromise of the forearm and hand. The aim of the planned systematic review and meta-analysis is to compare the wound-related, function-related and aesthetics-related outcome associated with full-thickness skin grafts (FTSG) and split-thickness skin grafts (STSG) in radial forearm free flap (RFFF) donor site closure. Methods: A systematic review and meta-analysis will be conducted. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines will be followed. Electronic databases and platforms (PubMed, Embase, Scopus, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), China National Knowledge Infrastructure (CNKI)) and clinical trial registries (ClinicalTrials.gov, the German Clinical Trials Register, the ISRCTN registry, the International Clinical Trials Registry Platform) will be searched using predefined search terms until 15 January 2024. A rerun of the search will be carried out within 12 months before publication of the review. Eligible studies should report on the occurrence of donor site complications after raising an RFFF and closure of the defect. Included closure techniques are techniques that use full-thickness skin grafts and split-thickness skin grafts. Excluded techniques for closure are primary wound closure without the use of skin graft. Outcomes are considered wound-, functional-, and aesthetics-related. Studies that will be included are randomized controlled trials (RCTs) and prospective and retrospective comparative cohort studies. Case-control studies, studies without a control group, animal studies and cadaveric studies will be excluded. Screening will be performed in a blinded fashion by two reviewers per study. A third reviewer resolves discrepancies. The risk of bias in the original studies will be assessed using the ROBINS-I and RoB 2 tools. Data synthesis will be done using Review Manager (RevMan) 5.4.1. If appropriate, a meta-analysis will be conducted. Between-study variability will be assessed using the I2 index. If necessary, R will be used. The quality of evidence for outcomes will eventually be assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Discussion: This study's findings may help us understand both closure techniques' complication rates and may have important implications for developing future guidelines for RFFF donor site management. If available data is limited and several questions remain unanswered, additional comparative studies will be needed. Systematic review registration: The protocol was developed in line with the PRISMA-P extension for protocols and was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on 17 September 2023 (registration number CRD42023351903). [ABSTRACT FROM AUTHOR]

Artificial dermal substitutes (ADMs) have been trialled to improve outcomes at the donor site following the harvesting of a radial forearm free flap (RFFF). This systematic review compares donor site aesthetic and functional outcomes, with the use of an ADM versus conventional practice. The databases Medline, Embase, Cochrane Library, Web of Science (Core Collection), and Scopus were searched for retrospective, prospective, and case-control studies and randomised control trials (RCTs) involving any ADM. Studies with adult patients having undergone RFFF harvesting and donor site repair with an ADM, commenting on appropriate clinical outcomes and without high risk of bias, were included. Direction-of-effect analysis was performed on relevant groupings of studies since heterogeneity in outcome measurement precluded meta-analyses. Across eight non-comparative studies included, 132 patients had donor site coverage with AlloDerm™, Integra™, Matriderm™, or Rapiderm. Across 11 comparative studies included, 240 patients had donor site coverage with fish-skin matrix, AlloDerm™, amniotic membrane, MegaDerm™, Hyalomatrix, Integra™, or Matriderm™. Five out of 11 comparative studies demonstrated superior aesthetic outcomes with ADMs according to at least one aesthetic metric compared to controls, whilst 6/11 demonstrated superior functional outcomes with ADMs. No study demonstrated poorer aesthetic or functional outcomes with an ADM compared to conventional practice. In summary, the lack of studies reporting poorer outcomes with them compared to conventional practices, and a cumulative effect direction in their favour, provide strong indications in support of the use of AlloDerm™, Integra™, or Matriderm™ grafts. Further comparative studies, including RCTs, are needed to reinforce these initial indications. [ABSTRACT FROM AUTHOR]

Background: Ultrasound shear wave elastography (SWE) noninvasively measures the stiffness of tissue by producing and measuring tissue deformation. Scar formation, a crucial aspect of wound healing, can lead to functional and aesthetic complications when pathological. While SWE has shown promise in dermatological evaluations, its role in surgical scar assessment remains underestimated. Our study aims to investigate SWE in evaluating surgical scars at the donor site after forearm free flap surgery in transgender patients. Methods: After radial forearm free flap harvesting, the donor site was grafted with a split-thickness skin graft with or without interposition of Matriderm. Eleven patients were evaluated more than one year after surgery, using SWE alongside scar characteristics, sensory outcomes, and patient satisfaction surveys. Results: Our study revealed no significant difference in stiffness (p > 0.15), pigmentation (p = 0.32), or erythema (p = 0.06) between operated and non-operated sides. The interposition of Matriderm did not influence the stiffness. Patients significantly (p < 0.0001) reported a loss of discrimination. Patients’ subjective scar evaluation appeared in line with our quantitative and objective results. Conclusions: This study contributes to the evolving understanding of SWE’s role in scar assessment, highlighting its feasibility in evaluating surgical scars. However, continued research efforts are necessary to establish SWE as a reliable and objective method for surgical scar evaluation and management.

Objective: The medial sural artery perforator (MSAP) flap has gained popularity in head and neck reconstruction primarily as a less morbid alternative to the radial forearm free flap (RFFF). However, no direct comparison of thickness exists among the MSAP, RFFF, and anterolateral thigh (ALT) flaps, which together represent the commonly utilized nonosseus‐free flaps in head and neck reconstruction. Thus, this study aimed to compare these flap sites and identify predictors of thickness that will aid in reconstructive surgical planning. Study Design: Cross‐sectional study. Setting: Tertiary referral hospital. Methods: The thickness of skin and subcutaneous tissue at the RFFF, MSAP, and ALT donor sites were measured in 54 adult patients using Doppler ultrasound. General linear models were generated to identify predictors of flap thickness. Results: The mean thickness of the RFFF, MSAP, and ALT flaps was 3.8 ± 2.2 mm, 7.4 ± 3.8 mm, and 9.6 ± 4.7 mm. Body mass index (BMI) was the only statistically significant contributing factor (p <.0001, coefficient: 0.15) for the RFFF. MSAP was affected by age (p =.006, coefficient = 0.06), female gender (p <.0001, coefficient = 3.2), and BMI (p <.001, coefficient = 0.25), while the ALT was affected by female gender (p =.0005, coefficient = 3.3) and BMI (p <.0001, coefficient = 0.35). Thus, the ratio of increase for flap thickness with respect to BMI is 3:5:7 for the RFFF, MSAP, and ALT flaps, respectively. Conclusion: The MSAP is about twice the thickness of the RFFF and 2 mm thinner than the ALT; however, 22% of patients had thicker MSAP than ALT flaps. As the strongest predictors of flap thickness, female gender, and BMI may be taken into consideration during surgical planning for reconstruction. [ABSTRACT FROM AUTHOR]

Introduction: Large chunks of the tissue are sacrificed during the surgical procedures for the treatment if oral cancers. Our goal was to assess the viability of “Buccal reconstruction using the anterolateral thigh (ALT) flaps, platysma myocutaneous (PM), and radial forearm free (RFF)”. Material and Methods: Sixty subjects were included in this investigation, and they were divided into 3 groups. The follow-up as accompanied for six months. Comparisons were made for the time for the operations, reduction in the width of the mouth opening and the survival rates of the flaps. The data that was collected for the above two parameters and compared for the significance using the ANOVA, keeping P < 0.05 as significant. Results: In the subjects with the PM, the width of the mouth opening reduced comparatively greater than that of the subjects who received other two flaps. The reduction in the mouth opening in the PM was significantly greater compared to that of the ALT and RFF. Survival was greater for the groups ALT and RFF compared to PM. Time of the surgery was the greatest for the ALT and least for the PF. Conclusion: The observations point to the fact that the PF requires more time than that of the other two flaps. The survival was however better for the ALT and RFF. Further research is suggested for suggesting an appropriative flap design.

Aims: The history of phallus construction parallels the advances made in plastic and reconstructive surgery whereby the era of microsurgery revolutionized numerous techniques. In 1993, we reported our early experience in phalloplasty. While the originally presented technique was a modification of the original design reported by Chang and Hwang, we now present further modifications of the past 30 years. Methods: Through critical review of our technical modifications, as well as others', we present a comprehensive review of elements of the radial forearm free flap phallus construction. Results: A radial forearm free flap is harvested and tubed to form the following components: urethra, shaft, and glans of the neophallus. When excess adipose tissue exists, the excess thickness is accommodated by increasing the proximal width of the flap. To optimize the venous drainage, the radial and ulnar superficial veins as well as the radial deep veins are included within the flap; however, venous flow is optimized through creation of an arteriovenous fistula within neo‐glans. To lengthen the native urethra, labia minora and vaginal mucosal flaps are employed at a preliminary stage during vaginectomy. New coronoplasty modifications offer esthetic refinements. Updates in scrotal reconstruction and implantation of erectile devices complete the total genitourinary reconstruction. Conclusions: Phallus construction has evolved significantly over time. While numerous techniques exist, no standard of care has been identified. Continue surgical evolution will provide modern solutions for problems most often encountered to improve overall outcomes for transgender and gender‐diverse patients pursuing masculinizing genitourinary reconstruction. [ABSTRACT FROM AUTHOR]

Purpose: The radial forearm free flap (RFFF) remains a workhorse in microsurgical reconstruction. Its failure is primarily due to problems with venous drainage; for this reason, controversy on venous anastomosis patterns still exists. This manuscript describes our experience in using a communicating vein to overcome the complications of venous drainage of the RFFF. Methods: Following a review of the vascular anatomy of the RFFF, we retrospectively review the use of the communicating vein and report our results, with the aim of overcoming the dichotomy "superficial versus deep venous system" and "single versus double anastomosis" and discussing the evidence of advantages in using a single microanastomosis with a communicating vein. Results: Our retrospective review included a total of 123 patients in which a RFFF was performed to reconstruct intraoral defects, performed with a single venous anastomosis using the communicating vein. Four patients (3.25%) required a return to theatre for revision of the venous anastomosis and one case resulted in flap failure due to arterial insufficiency (0.81%). Conclusions: Our series highlights the constant presence of the communicating vein, although with variations of origin and course that did not preclude the possibility to correctly perform the anastomosis. Advantages of a single microanastomosis with the communicating vein include ease, speed, reliability and versatility in planning the anastomosis. Based on our results, the use of the communicating vein showed comparable and, in some cases, more favourable results when compared to venous anastomotic complications reported in the literature. [ABSTRACT FROM AUTHOR]

Background The radial forearm free flap (RFFF) is widely used and is considered one of the workhorse flaps in oncologic head and neck reconstructions. However, the potential for significant donor-site morbidity remains a major drawback. Although various donor-site problems have been reported, the incidence of neuropathic pain and possible predicting factors remain unclear. This study aimed to identify the incidence, prognostic factors, and impact on quality of life of neuropathic pain following RFFF harvest. Methods In this multicenter, cross-sectional study, 167 patients who underwent an RFFF reconstruction between 2010 and 2020 were included. Baseline characteristics were collected by medical charts. All patients received questionnaires to measure patient's pain (Doleur Neuropathique 4 and visual analog scale, pain), hand function (Patient-Reported Wrist and Hand Evaluation), and quality of life (EuroQol 5D). Multiple logistic regression was used to identify prognostic factors associated with outcomes. Results A total of 114 patients (68%) completed the questionnaire. Neuropathic pain was present in 18% of all patients. Donor-site wound problems, mostly tendon exposure, occurred in 32% and was significantly correlated with neuropathic pain (p = 0.003). Neuropathic pain was significantly associated with poorer quality of life (p < 0.001) and poorer hand function (p < 0.001). Conclusion Almost one-fifth of all patients deal with neuropathic pain following RFFF harvest. Neuropathic pain is significantly correlated with poorer hand function and a poorer quality of life. Therefore, future research should focus on analyzing surgical factors such as the management of wound problems and primary denervation to improve hand function and quality of life of these patients. [ABSTRACT FROM AUTHOR]

Aim: The authors present the possibilities of reconstructive surgery using free microvascular bone-containing flaps in the treatment of defects in the head and neck area. The defects resulted from the resection of head and neck tumours, congenital disorders, and radiation damage. The authors discuss the difficulties that may arise during the postoperative period, including the maintenance of the flap viability, the healing of the donor site and systemic problems. Material and methods: The study reports 33 reconstruction surgeries in 31 patients with different flaps and briefly describes their advantages and technical difficulties that may occur during the microvascular anastomoses. Results: The authors emphasise the importance of proper eligibility determination for the surgery as well as the need to discuss the course of the surgery and recovery and other possible treatment options with patients and their families. The complications and their management were also described. The authors discuss in detail three cases in whom different types of reconstruction procedures were performed and draw attention to the importance of postoperative care, consisting of the constant monitoring of flap viability by a qualified staff of the Otolaryngology Department and appropriate anticoagulant therapy. [ABSTRACT FROM AUTHOR]

A retrospective cohort study of 253 radial forearm free flap (RFFF) procedures in head and neck reconstruction performed in our department between 2005 and 2018 was reviewed. In order to explore the effects between single and dual anastomoses, we applied Fisher's exact test for statistical analysis. Although no flap failure was identified, more venous compromises were observed in single anastomosis group (5/80 vs. 1/173). We conclude that dual venous anastomoses can reduce venous compromise resulted from unexpected causes in RFFF transfer. Therefore, we especially recommend dual venous anastomoses for those who cannot withstand a second surgery. [ABSTRACT FROM AUTHOR]

Introduction: The radial forearm free flap (RFFF) is a commonly used free flap for the reconstruction of orofacial defects because of its versatility and reliability. The donor site is closed with either split or full-thickness skin graft, and one of the common donor site morbidities is skin graft failure. Various techniques to minimise skin graft failure were reported, and we compared the skin graft techniques with and without plaster back slab dressing in the radial forearm donor site. Materials and Methods: This is a retrospective study of 75 patients who had RFFF for reconstruction of oral cavity cancer at two different tertiary teaching hospitals in the United Kingdom between April 2015 and March 2020. Thirty-nine patients from Hospital one had volar back slap, bolster dressing and crepe bandage. In contrast, 36 patients from Hospital two had only pressure dressing without a back slab. Results: The mean age of the study population was 60.65 (P = 0.274). In both groups, two patients had donor site complications. However, there was no significant difference in the donor site skin graft complications with a P = 0.662. Discussion: There was no evidence in the literature to support an ideal bandage for skin graft at the RFFF donor site. Our comparison of two techniques of skin graft dressings with and without back slap did not show any difference in the skin graft take, and the volar back slab did not add any additional benefits. The simple use of foam as a bolster dressing without a back slab is ideal for the radial forearm free flap donor site. [ABSTRACT FROM AUTHOR]

The purpose of the study was to assess and compare the quality of speech and swallowing between three reconstruction options (primary closure—group A, secondary intention healing—group B and flap reconstruction—group C), in small to moderate sized onco-surgical defects of oral tongue. 47 patients fulfilled the eligibility criteria during the study period, of which, 15 belonged to group A, 16 belonged to group B, 16 were in group C. Speech and swallowing assessment was done using Speech Intelligibility Assessment score and MD Anderson Dysphagia Inventory, respectively. The above tests were administered pre-operatively, 1 month and 6 months post-operativey in all the study participants. The average scores of speech intelligibility at 1 month were 66.13% (±19.96), 70.04% (±12.28) and 37.31% (±11.29) for groups A, B and C respectively. Similarly, average long term scores for speech intelligibility in these three groups were 72.7% (±17.72), 83.3% (±12.78) and 52.8% (±11.74) respectively. With regards to swallowing the composite scores at 1 month were 73.67 (±13.69), 68.31 (±16.06) and 41.81 (±5.44), and at 6 months were 83.2 (±10.24), 79.31 (±12.29) and 57.88 (±7.37), respectively for groups A, B and C. All the differences were statistically significant (p < 0.05). Healing by secondary intention offered the best functional outcome in terms of speech intelligibility, and primary closure offered best swallowing outcomes in operated cases of oral tongue. This trial has been registered with the Clinical Trials Registry—India in December 2018 (CTRI Reg. No: CTRI/2018/12/016803). [ABSTRACT FROM AUTHOR]

Objective: Donor site deformities remain the primary issues after radial forearm free flap (RFFF) translocations. This study introduced a local full‐thickness skin graft (FTSG) from an adjacent cutaneous area to manage RFFF donor sites and evaluated the esthetic and functional outcomes post‐operatively. Patients and methods: This was a retrospective study among patients undergoing ablative surgery for head and neck tumors followed by defect reconstruction using a RFFF. The RFFF donor site defects were covered by local FTSGs from the adjacent skins whose harvesting was assisted by a forearm model or traditional FTSGs from abdomen. The color matching degree, surgical scars, ranges of wrist movement, and grip strengths in donor forearms were assessed in two groups at twelve months after surgery. Results: Patients undergoing local FTSGs recovery exhibited better color matching than those repaired by traditional FTSGs from the abdomen. In forearm model, the local FTSGs width should be less than 22% of the forearm circumference located 5 cm away from the center of Fossa cubitalis. All the local FTSGs transplanted with this technique showed primary or secondary healing. Conclusions: This study demonstrated using this innovatively designed local FTSGs to close RFFF donor sites was more advantageous than traditional methods. [ABSTRACT FROM AUTHOR]

Tracheoesophageal fistula (TEF) constitutes a rare, but serious complication in laryngectomized patients, usually occurring after radiotherapy. TEF may occur spontaneously or may be due to enlargement of the TEF created for placement of a voice prosthesis. Surgical treatment of TEF can be complex, especially in the presence of a concomitant pharyngoesophageal stenosis (PES), and is associated with a high failure rate. In this article, we describe the surgical reconstruction technique for TEF associated with PES using a double skin paddle fasciocutaneous radial forearm free flap. The key points of this technique consist of correct positioning of the 2 skin paddles in order to reconstruct the anterior pharyngoesophageal wall and posterior tracheal wall, as well as de-epidermization of the intermediate part of the flap, which is then placed in the tracheoesophageal space. [ABSTRACT FROM AUTHOR]

Background. Radial forearm free flap is one of the most frequently used in the head and neck reconstruction. A significant disadvantage is the appearance of the donor site. We have developed and introduced into clinical practice a V-shaped fabrication skin of the flap, which allows direct closure of the donor site and reduces morbidity. Aim. To assess the possibility of direct closure of the donor site and to reduce the morbidity of the donor site when performing the V-shaped fabrication of the skin area of the flap. Materials and methods. During the period from 2014 to 2020, the radial free flap was used in 43 cases. In 15 (35%) cases, a V-shaped fabrication of the skin area was used during flap harvest, which made it possible to carry out a direct closure of the donor site. The length of the skin area stretched from the top of the wrist, not reaching 34 cm to the elbow bend and varied from 715 cm, on average 12 cm. The width of the flap was determined by the elasticity of the forearm skin, was maximum in the middle third and varied from 2 up to 4 cm, averaging 3.3 cm. If necessary, the upper and lower edges of the skin area can be sutured together, as well as the entire medial edge of the flap. This technique increases the flap width by almost 2 times. This arrangement was applied in 8 cases. Results. When comparing the results of using the two techniques, the following data were obtained: "V-shaped" fabrication of the skin was used mainly in women (11/15 73%) for reconstruction limited defects in the retromolar region (5/15), soft (4/15) or hard palate (6/15). Most of the patients had localized T1-T2 (10/15) stage. None of the patients had any problems with the healing of the donor area. An excellent aesthetic result was obtained in all patients. In the group of standard harvest, the predominance of males was noted (17/28). Defects had a varied localization, most patients was with relapses after chemo-radiation treatment (10/28) or primary locally advanced T3-T4 stage process (6/28) 16, with a localized T1-T2 stage (11/28) 11, in one case, delayed reconstruction was performed. In all cases, the plastic of the donor site was performed with a split skin autograft. Partial necrosis of the donor site flap was observed in 9 patients (32%), in 4 cases with exposure of the flexor muscle tendon. Conclusion. As a result of the comparative analysis of the two methods, we concluded that the use of V-shaped fabrication of the skin area of the radial forearm flap allows to obtain better aesthetic results of the donor site, however, the use of this technique leads to a significant reduction in the length of the vascular pedicle and a decrease in the width of the flap.

Background: Considering the burden of oral cancers in Indian subcontinent many patients undergo ablative surgery for oral cancer. Buccal mucosa and tongue are commonly affected due to etiology being chewable tobacco. Radial forearm flap is commonly selected to reconstruct buccal mucosal or tongue lining. Material And Methods: 100 patients are selected who underwent ablative surgery and reconstruction by free radial forearm flap. Full thickness graft was harvested in all those form groin area and groin was closed primary. The results were evaluated for graft take, aesthetic appearance and hand functions from grade 1 to 5. Result: In most of patients graft take was almost 100%. Epidermal loss was noted in some patients but dermal take was present. None of the patients required to undergo re-grafting or debridement for forearm. Majority of patients were in grade V; 82 for cosmetic analysis and 83 for functional analysis. Mean value for cosmetic was 7.73±0.7 and for functions it was 4.78±0.52. Conclusion: Full thickness skin graft provides stable and better outcomes. Graft loss is a major fear but is good technique and post op care if taken, that serves as much better option. [ABSTRACT FROM AUTHOR]

Background: The radial forearm free flap (RFFF) is one of the most common reconstructive choices for head and neck soft tissue defects worldwide. One of the techniques to cover up the donor site defect is based on the use of split-thickness (STSG) or full-thickness skin grafts (FTSG). Methods: Ours is a retrospective study including 36 RFFF reconstructive surgery patients at the University Hospitals of Verona and Parma treated between 2016 and 2020, with more than 6 months' follow-up. Nineteen patients received a FTSG, locally harvested from the forearm, while 17 a STSG from the thigh. We used two already validated scales for the evaluation of the surgical scars. The first one is the Patient and Observer Scar Assessment Scale that rates vascularity, pigmentation, thickness, relief, pliability, and the surface area, and it incorporates the patient's assessments of pain, itching, colour, stiffness, thickness, and relief. The second questionnaire was developed by Liu in 2011 to assess the functionality of the donor site from a patient's perspective. Results: Pigmentation, thickness, relief, and surface area were statistically better in the FTSG than in the STSG group, while, according to the patients, the functional results turned out to be similar. Conclusions: From our experience, the locally harvested FTSG is to be considered the best alternative, with a better aesthetic outcome than the STSG harvested from the thigh and with a higher degree of protection provided to the forearm flexor tendons, without the need for an additional donor site. Level of evidence: Level III, therapeutic study. [ABSTRACT FROM AUTHOR]

The study aimed at comparing outcomes between split-thickness skin graft (STSG) and local ipsilateral full-thickness skin graft (FTSG) after radial forearm free flap defect closure. A comprehensive study protocol for objective and subjective assessment was established for this retrospective, single-center study. Clinical examinations were carried out, encompassing measuring wrist and finger range of movement and grip strength, testing skin sensitivity, and evaluating aesthetics using the Patient and Observer Scar Assessment Scale (POSAS). In addition, medical history, and questionnaire, including Cold Intolerance Severity Score (CISS) and 18 items, were used to assess satisfaction, functional limitations, and complaints. 44 patients were examined, and 40 patients included, who had received STSG (group 1; n = 19) respectively local FTSG from the ipsilateral forearm (group 2; n = 21) at least three months previously. Significantly lower values for parameters pigmentation, relief (p = 0.015), overall impression (p = 0.044), as well as mean POSAS observer scale total score (p = 0.046) and no complaints wearing a wristwatch (p = 0.012) were shown in group 2 (FTSG). Within the limitations of the study, it seems that FTSG harvested from the forearm should be preferred over STSG to cover RFFF donor site whenever appropriate, because of beneficial outcomes, while providing single intervention closure and avoiding secondary donor site. [ABSTRACT FROM AUTHOR]

The radial forearm free flap (RFFF) is one option of many free-tissue flaps that is frequently selected to reconstruct defects of the head and neck. It is popular due to its relatively thin and pliable associated soft tissue, reliable supplying vasculature, and appropriate diameter and length of the supplying vessels to perform microvascular anastomosis. This case report describes the use of the RFFF to reconstruct an oral cavity defect following tumor resection in a patient who required adjustment of the typical RFFF design. This patient has a significant psychiatric history leading to self-induced forearm lacerations that resulted in substantial scarring of her bilateral forearms in the anatomical area typically included in the RFFF. Since the RFFF was the optimal reconstructive option for this patient, the design of the RFFF was able to be moved proximally up her forearm to avoid inclusion of the scars in the flap. Adequate blood flow of the ulnar artery was confirmed with an Allen0s test preoperatively to ensure the radial artery could be taken as part of the RFFF without causing ischemia of the hand. Following surgical resection of the patient0s tumor, the RFFF was harvested and inset to reconstruct the resulting oral cavity defect. The patient has had no complications following her resection and reconstruction to date. This report highlights the adaptability of the RFFF, allowing adjustments to typical flap design to optimize outcomes for each individualized patient. [ABSTRACT FROM AUTHOR]

Background: Radial forearm free flap phalloplasty (RFFF) is a set of complex reconstructive procedures aimed at creating an aesthetic and functional penis in transgender patients. Sensory recovery in the neophallus and donor site is crucial for optimizing outcomes, but the few prior studies that exist assess neophallus sensation at limited locations and time points. The purpose of this study was to prospectively quantify sensory outcomes in the neophallus and donor site following RFFF phalloplasty., Methods: Sensation testing occurred prospectively over February 2019-January 2021 on Stage 1 RFFF phalloplasty patients using the Pressure Specified Sensory Device (PSSD). On the neophallus, one-point discrimination (1PS) pressure threshold and lengthwise sensory recovery were measured at six circumferential locations proximally to distally. On the donor site, 1PS was measured at three locations on the donor hand., Results: Nineteen patients were included (average age 34.0 years old, range 18-53 years). Among patients that received neophallus testing (n = 13), eight had at least two follow-up appointments. Six of these patients had sensation as of their most recent measurement (75.0%), with an average of 73 days to regain sensation. There was a significantly greater proportion of patients with sensation at the right ventral (80.0% after 3 months vs. 11.1%-60.0% before 3 months, p = 0.024) and right lateral (100.0% after 3 months vs. 11.1%-60.0% before 3 months, p = 0.004) aspects of the neophallus over time. Pressure required to elicit sensation decreased by 18.0% from 1 week-1 month postoperatively to 3-7.7 months postoperatively in the right ventral neophallus (96.2 g/mm 2  ± 11.3 g/mm 2 to 56.6 ± 39.9 g/mm 2 , p = 0.037). Among patients that received donor site testing (n = 11), mixed effects regression analysis with random intercepts demonstrated significant changes in the thumb (3.4 g/mm 2 ± 1.4 g/mm 2 , p < 0.05) and webspace (13.5 g/mm 2 ± 4.9 g/mm 2 , p < 0.01) that returned to baseline at 3 months postoperatively (1.7 g/mm 2  ± 1.0 g/mm 2 , p > 0.05, and 2.3 g/mm 2  ± 4.0 g/mm 2 , p > 0.05, respectively)., Conclusion: This pilot study demonstrates that quantitative sensory testing can be used to monitor post-phalloplasty sensory changes. Recovery was significantly associated with contralateral (i.e, right side in a left forearm RFF) aspects of the neophallus, suggesting a possible pattern of circumferential sensory innervation via RFFF sensory nerves. Future studies with a larger sample size and longer follow-ups are necessary to fully characterize sensory recovery in phalloplasty patients., (© 2024 Wiley Periodicals LLC.)

Background: The most commonly used free flaps are the anterolateral thigh (ALT) free flap and the radial forearm (RF) free flap, which often have overlapping indications. The aim of the present study is to compare the aesthetic and functional consequences for the donor site in patients undergoing ALT or RF flap harvesting. Methods: A questionnaire was administered to each patient to assess the functionality and aesthetics of the donor site. We used three different scales validated in the literature: the Patient and Observer Scar Assessment Scale (POSAS), the Manchester Scar Scale (MSS), and the donor site functionality questionnaire developed by Liu and colleagues. A total of 54 patients underwent ALT or RF free flap harvesting at the University Hospital of Verona in the period between February 2016 and September 2019. Of these, 14 had died at the time of the study. In addition, a complete follow-up was not available in 9 patients and they were therefore excluded from the study. Therefore, a total of 31 patients, 15 of whom underwent ALT flap harvesting (48%) and 16 RF flap harvesting (52%), were analyzed in the present study. Out of the 31 patients, 11 (36%) were female and 20 (64%) were male. The mean age at the time of surgery was 61 years (± 16 (SD), and ranging from 23 to 87 years). The flap size was on average 142.6 cm2 (90–198) in the ALT group and 36.5 cm2 (20–63) in the RFFF group. Results: Overall observer total score of the POSAS was 12 (8–15) for the ALT flap and 9.5 for the RF flap. For the patients' opinion of the POSAS scale, the overall patient total score was 16 for the ALT flap and 9 for the RF flap. There was no difference in overall observer total score nor in patients opinion score between ALT and RF (12 (8–15) compared to 9.5 (8–12.25) and 16 (9.5–20) compared to 9 (7.75–15) (p = 0.28 and p = 0.13, respectively). For the MSS, the RF flap had a significantly better result with the VAS (visual analog scale) score (p = 0.04) compared with the ALT flap. In total, 94% of patients undergoing RF flap harvesting were satisfied with the appearance of the forearm against 73% of patients with the ALT flap. Conclusions: In this case series, the RF donor site achieved slightly better aesthetic and functional outcomes than the ALT donor site. Our results are discordant with the majority of published international studies, and are probably related to surgical management of the RF donor site using a locally harvested full-thickness skin graft (FTSG). Level of evidence: Level III, therapeutic/prognostic study. [ABSTRACT FROM AUTHOR]

Objectives: To assess the feasibility of radial forearm free flap (RFFF) reconstruction of glossectomy defects without tracheostomy tube (TT). Methods: Retrospective review of patients with at least oral tongue defects who underwent RFFF reconstruction. Pre- and intra-operative factors were documented. Post-operative respiratory complications included inability to extubate, pneumonia, or need for re-intubation or TT within 30 days. Results: Twenty-one patients underwent RFFF reconstruction without TT, and 36 patients with TT. The average hospital length of stay was 1.5 days shorter in those without TT (P <.01). Two patients who underwent TT placement experienced a respiratory complication (P =.27). There were no respiratory complications among those without TT. After multivariate analyses, large tongue base defect (>25% resection, P <.001) and bilateral neck dissection (P <.001) were independently associated with TT placement. Conclusions: In our experience, RFFF reconstruction of glossectomy defects is feasible without TT among selected patients with small tongue base defects (≤25% resection) and unilateral neck dissection. [ABSTRACT FROM AUTHOR]

The vascularised forearm free flap is a workhorse flap for the reconstruction of many types of soft tissue defects. However, the difference in donor-site morbidity between the radial forearm free flap (RFFF) and ulnar forearm free flap (UFFF) remains controversial. This study aimed to compare the donor-site outcomes of RFFF and UFFF. We searched PubMed, EMBASE, Web of Science, clinicaltrials.gov, Cochrane Library, and Chinese Biomedical Literature Database up to August 10, 2021, to identify studies on donor-site outcomes of RFFF versus UFFF in patients undergoing reconstructive surgery. Two authors individually extracted data and performed quality assessments of the selected articles. The overall morbidity and overall effect of individual complications of the donor site were analysed. In total, 288 cases from five studies were included in our analysis. The UFFF group was significantly superior to the RFFF group regarding overall morbidity and overall effect of individual complications of the donor site. The morbidity of UFFF donor sites was significantly lower than that of RFFF, and UFFF may be an ideal substitute for RFFF in reconstructive surgery. However, additional large-scale studies are necessary to confirm this finding. [ABSTRACT FROM AUTHOR]

Background: The radial forearm free flap (RFFF) is associated with troublesome donor site morbidity related to split thickness skin grafting (STSG). The radial forearm snake flap with primary closure of the donor site may reduce donor site complications. Methods: Single institution, retrospective cohort study comparing rates of delayed donor site wound healing and tendon exposure in 52 patients undergoing radial forearm snake flap and 95 patients undergoing conventional RFFF with STSG closure of the donor site. Results: Tendon exposure occurred in zero (0%) patients undergoing snake flap and four (4.2%) patients undergoing conventional RFFF (0/52 vs. 4/95; p = 0.297). Delayed wound healing occurred in zero (0%) patients undergoing snake flap and 19 (20.0%) patients undergoing conventional RFFF (0/52 vs. 19/95; p < 0.001). Conclusions: The radial forearm snake flap provides an alternative to conventional RFFF harvest, which enables primary donor site closure with reduced rates of delayed donor site healing. [ABSTRACT FROM AUTHOR]

Background: Palatal defects are still challenging for the reconstructive surgeon since the palate carries important functional roles in swallowing and articulating while providing an adequate airway. The aim of this article is to discuss the preferred free flap types for palatal reconstruction and present the functional outcome. Material and Methods: Records of patients who underwent microsurgical palatal reconstruction between 2012 and 2017 were reviewed for demographic properties, defect properties, flap of choice, and complication rates. A questionnaire was applied to the patients for assessment of speech, swallowing, regurgitation, snoring, and overall satisfaction. Results: Four patients were operated for palatal defects with a mean size of 23.25 cm2. The most commonly used free flap was the radial forearm flap in our four patient series. All patients reported improvement for every functional criterion in the questionnaire. Conclusion: Free flaps are an acceptable method for restoring palatal function. Radial forearm free flap was the flap of choice for reconstruction of large palatal defects in this retrospective review.

Background: Several decades have witnessed the use of free flaps in clinical science. With the advancement and refinement in operative techniques, survival rates of free flaps have increased. There is a need to compare the efficacy and safety of anterolateral thigh (ALT) flap and radial forearm free flap (RFFF) in head-and-neck reconstruction surgeries. Objective: The objective of this study was to compare the ALT flap and RFFF in head-and-neck reconstruction. Materials and Methods: This prospective study was carried out among 25 patients posted for head-and-neck reconstruction in whom either a RFFF or an ALT free flap (ALTF) was performed. Group A had 16 patients reconstructed using the RFFF. Group B had 9 patients reconstructed using ALTF. Results: Majority of the cases were of buccal mucosa cancer. Majority of the RFFFs were performed in buccal mucosa carcinoma patients (43.75%). Majority of the patients with squamous cell carcinoma of the scalp underwent ALTF. RFFFs were most commonly performed in oral cavity (43.75%). Most of the cases of ALTF were performed in the midface and scalp. Mean values of pedicle length, flap length, flap width, and flap thickness were significantly less in the RFFF group compared to the ALTF group. However, the mean time of harvest (min) was significantly less in the RFFF group allowing quick harvest. The difference in donor-site complications in the two groups was not statistically significant except donor-site social stigma. Patients of the RFFF group complained of donor-site social stigma due to ugly looking Split thickness skin graft (STSG) patch at the donor site. The average stay in the hospital after surgery was not found to be statistically significant. Conclusion: ALTF allows a harvest of large tissue for reconstruction as compared to RFFF. Donor-site morbidity is comparable in both the groups except donor-site appearance. RFFFs are harvested easily in less time as compared to Anterolateral thigh free flap (ALTF) due to the complex anatomy of ALTF.

Negative‐pressure wound therapy (NPWT) is often used for skin graft site dressing, and several studies have reported that its use improves skin graft failure in the forearm flap donor site. The present systematic review aimed to evaluate the efficacy of NPWT with skin graft for donor‐site closure in radial forearm free flap (RFFF) reconstruction. A systematic search in PubMed, Web of Science, and Cochrane Library databases was conducted. The search terms used for PubMed were ([radial forearm]) AND ([donor]) AND ([negative pressure or vacuum]). This review was registered in the International Prospective Register of Systematic Reviews and performed in accordance with the preferred reporting items for systematic reviews and meta‐analyses statement. Three prospective randomised controlled trials and three retrospective comparative studies were included. Compared with conventional bolster dressing, the use of NPWT dressing did not lead to significant improvements in partial skin graft loss, tendon exposure, and other complications. NPWT improved hand functionality earlier; nonetheless, the cost of the device and dressings was a disadvantage. The use of NPWT for skin graft fixation in the RFFF donor site is not generally recommended. [ABSTRACT FROM AUTHOR]

Objectives: Free tissue reconstruction of the head and neck must be initially overcorrected due to expected postoperative free flap volume loss, which can be accelerated by adjuvant radiation therapy. In this study, we aim to identify patient and treatment-specific factors that may significantly contribute to this phenomenon and translate these characteristics into a predictive model for expected percent free flap volume loss in a given patient. Methods: Patients with a history of oral cavity and/or oropharyngeal cancer who underwent nonosseous free flap reconstruction were reviewed between January 2009 and November 2018 at a tertiary care center. Demographics/characteristics, total radiation dose, radiation fractionation (RF), and pre/postradiation free flap volume as evaluated by computed tomography imaging were collected. Free flap volume was measured by a fellowship-trained neuroradiologist in all cases. Only patients receiving adjuvant radiotherapy with available pre/postradiation imaging were included. Multivariable linear regression modeling for prediction of free flap volume loss was performed with optimization via stepwise elimination. Results: Thirty patients were included for analysis. Mean flap volume loss was 42.7% ± 17.4%. The model predicted flap volume loss in a significant fashion (P =.004, R2 = 0.49) with a mean magnitude of error of 9.8% ± 7.5%. Age (β = 0.01, P =.003) and RF (β = −0.01, P =.009) were individual predictors of flap volume loss. Conclusions: Our model predicts percent free flap volume loss in a significant fashion. Age and RF are individual predictors of free flap volume loss, the latter being a novel finding that is also modifiable through hyperfractionation radiotherapy schedules. [ABSTRACT FROM AUTHOR]

In phalloplasty, there is a lack of standardized follow-up examinations of motor function and strength after harvesting oversized radial forearm free flaps (RFFF). We evaluated the donor site of 20 transmen after phalloplasty, using a multimodal, standardized approach, assessing the following parameters: opposition of the thumb, composite range of motion of the finger joints, grip strength, mobility of the wrist, lesion of the superficial branch of the radial nerve, the dorsal branch of the ulnar nerve, the sensation of pain, and cold intolerance. The contralateral, nonoperated forearm was used as a control. No impairment of the mobility of the thumb (Kapandji score median 10, range 5–10) or fingers (all fingers at both sides pulp-to-palm 0 cm, nail-to-table 0 cm) were detected. Grip strength (median 36,3kg, p=0.629) and wrist extension (62.5°vs.70°, p=0.357), flexion (70°vs.70°, p=0.535), pronation (90°vs.90°), supination (90°vs.90°), radial (30°vs.30°, p=0.195), and ulnar deviation (40°vs.50°, p=0.125) did not statistically differ between donor and control hand. Injury of the dorsal branch of the ulnar nerve was uncommon (0% hypoesthesia, 10% positive Tinel's sign). We did not observe any persistent pain of the donor forearm (NRS median 0, range 0–9). We did observe irritation of the superficial branch of the radial nerve (hypoesthesia 40%, neuroma 45%). The harvest of an oversized RFFF for phalloplasty does not cause any significant difference in motor function or strength between the donor and nonoperated hand. A potential risk of injuring the radial nerve branch is to be avoided. An aesthetic impairment could be addressed in future studies. [ABSTRACT FROM AUTHOR]

Purpose: Radial forearm free flap (RFFF) being a workhorse flap in head and neck reconstruction, we investigated its donor site delayed consequences. Methods: Multicentric case series evaluating 189 patients who underwent RFFF for carcinologic reasons at least 6 months before. Patients and surgeon's appreciation regarding the aesthetic and functional consequences of the flap harvest on their daily life were evaluated by questionnaires using likert scales. Medical data were collected from patients' charts retrospectively. Results: Thirty percent of patients had at least one sequelae. Experiencing a graft necrosis did not worsen long-term results. Cosmetic satisfaction was significantly worst for women, according to patients' and surgeons' opinion. For 81% and 92% patients, respectively, the flap harvest had no impact on daily life nor sport practice. Ratio between the benefits of reconstruction and the sequelae at the donor site was judged "excellent" for 77% patients. Conclusions: Although objectively important, RFFF morbidity has little impact in head and neck cancer patient's life. [ABSTRACT FROM AUTHOR]

Phalloplasty has matured considerably over the last decades in reconstructive options and technical refinements, thanks to increasing recognition of gender dysphoria. The primary goals of performing a phalloplasty are to facilitate sexual penetration, protective sensation, orgasm, standing micturition, and natural aesthetic, ideally in few stages and with minimal morbidity. Radial forearm free flap, anterolateral flap, and metoidioplasty are the most common options, each with a unique profile of complications, aesthetic, and functional outcomes. Choices for reconstruction must be tailored to the individual patient’s goals and available tissue characteristics.

Objective: To evaluate the donor site morbidity associated with the radial forearm free flap surgery. Study Design: Case series study. Place and Duration of Study: Departments of Plastic and Reconstructive Surgery, Combined Military Hospital Rawalpindi and Bahawalpur, from Jul 2011 to Jul 2017. Methodology: One hundred and nineteen patients, who underwent radial forearm free flap surgery, were included in the study. Patients were followed up at first and second week and then at six months. Patients were examined for wound infection, radial nerve injury, flexor tendon desiccation, cold intolerance, persistent post-op pain, wrist mobility, and pinch and grip strength (using a dynamometer). Results: There were a total 109 patients out of which 78 (71.6%) were male patients and 31 (28.4%) were female patients. The mean age was 35 ±12 years (range: 16 to 64) years. Three (2.8%) patients had early wound infection. Two (1.8%) patients had injury to sensory branch of the radial nerve and two (1.8%) had desiccation of flexor tendons near wrist. On six-month’s follow-up, five (4.6%) patients developed cold intolerance while six (5.5%) patients had persistent post-operative pain. Four (3.7%) patients developed reduced wrist mobility and same percentage of patients (3.7%) had reduced pinch and grip strength. Conclusion: The donor site in radial forearm free flap surgery carries donor site morbidity that can be minimized by careful and meticulous surgical techniques.

Reconstruction of pharyngoesophageal defects following total laryngectomy poses a significant challenge. The goals of reconstruction are to provide alimentary tract continuity and to restore speech and swallowing functions. Patients with radiotherapy recurrent disease often have unfavourable tissue for healing with a high incidence of pharyngocutaneous fistula. We discuss utilisation of a double skin paddle radial forearm free flap for pharyngoesophageal reconstruction as well as a cutaneous skin defect. A 53-year-old female was referred to our department for reconstruction of her total laryngectomy defect secondary to radio-recurrent right laryngeal squamous cell carcinoma with extra-laryngeal spread. Reconstruction planning was challenging as the patient was an obese, heavy smoker with significantly irradiated neck skin. A tubed radial artery forearm free flap was planned for pharyngoesophageal reconstruction however due to the extent of radiotherapy skin damage; primary closure of the neck defect was not possible. The flap was modified into a double paddle design to reconstruct the pharyngoesophageal defect, with the second skin paddle folded over to reconstruct the cutaneous defect. Multiple reconstructive options have been described in the literature for primary laryngectomy defects. Complex patients with recurrence particularly after neoadjuvant treatment are often poor candidates for reconstruction with poor tissue viability. Providing sufficient and adequate soft-tissue coverage is essential to minimise complications. We have described an intra-operatively planned, novel technique of reconstruction. Pre-operative anticipation may assist in addressing complexities encountered particularly in settings of hostile native skin., Competing Interests: None., (Crown Copyright © 2024 Published by Elsevier Ltd on behalf of British Association of Plastic, Reconstructive and Aesthetic Surgeons.)