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1. The Severity of Congenital Hypothyroidism With Gland-In-Situ Predicts Molecular Yield by Targeted Next-Generation Sequencing

Author

Levaillant, Lucie, primary, Bouhours-Nouet, Natacha, additional, Illouz, Frédéric, additional, Amsellem Jager, Jessica, additional, Bachelot, Anne, additional, Barat, Pascal, additional, Baron, Sabine, additional, Bensignor, Candace, additional, Brac De La Perriere, Aude, additional, Braik Djellas, Yasmine, additional, Caillot, Morgane, additional, Caldagues, Emmanuelle, additional, Campas, Marie-Neige, additional, Caquard, Marylène, additional, Cartault, Audrey, additional, Cheignon, Julie, additional, Decrequy, Anne, additional, Delemer, Brigitte, additional, Dieckmann, Katherine, additional, Donzeau, Aurélie, additional, Doye, Emilie, additional, Fradin, Mélanie, additional, Gaudillière, Mélanie, additional, Gatelais, Frédérique, additional, Gorce, Magali, additional, Hazart, Isabelle, additional, Houcinat, Nada, additional, Houdon, Laure, additional, Ister-Salome, Marielle, additional, Jozwiak, Lucie, additional, Jeannoel, Patrick, additional, Labarthe, Francois, additional, Lacombe, Didier, additional, Lambert, Anne-Sophie, additional, Lefevre, Christine, additional, Leheup, Bruno, additional, Leroy, Clara, additional, Maisonneuve, Benedicte, additional, Marchand, Isis, additional, Marquant, Emeline, additional, Muszlak, Matthias, additional, Pantalone, Letitia, additional, Pochelu, Sandra, additional, Quelin, Chloé, additional, Radet, Catherine, additional, Renoult-Pierre, Peggy, additional, Reynaud, Rachel, additional, Rouleau, Stéphanie, additional, Teinturier, Cécile, additional, Thevenon, Julien, additional, Turlotte, Caroline, additional, Valle, Aline, additional, Vierge, Melody, additional, Villanueva, Carine, additional, Ziegler, Alban, additional, Dieu, Xavier, additional, Bouzamondo, Nathalie, additional, Rodien, Patrice, additional, Prunier-Mirebeau, Delphine, additional, and Coutant, Régis, additional

Published
2023
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2. Additional file 1: of Association of environmental markers with childhood type 1 diabetes mellitus revealed by a long questionnaire on early life exposures and lifestyle in a case–control study

Author

F. Balazard, S. Le Fur, S. Valtat, A. Valleron, P. Bougnères, Thevenieau, Dominique, Chatel, Corinne, Desailloud, Rachel, Bony-Trifunovic, Hélène, Pierre-Henri Ducluzeau, Coutant, Régis, Caudrelier, Sophie, Pambou, Armelle, Dubosclard, Emmanuelle, Joubert, Florence, Jan, Philippe, Marcoux, Estelle, Bertrand, Anne-Marie, Mignot, Brigitte, Penformis, Alfred, Stuckens, Chantal, Piquemal, Régis, Barat, Pascal, Rigalleau, Vincent, Stheneur, Chantal, Fournier, Sylviane, Kerlan, Véronique, Metz, Chantal, Fargeot-Espaliat, Anne, Reznic, Yves, Olivier, Frédérique, Gueorguieva, Iva, Monier, Arnaud, Radet, Catherine, Gajdos, Vincent, Terral, Daniel, Vervel, Christine, Bendifallah, Djamel, Signor, Candace, Dervaux, Daniel, Abdelkader Benmahammed, Guy-André Loeuille, Popelard, Françoise, Guillou, Agnès, Pierre-Yves Benhamou, Khoury, Jamil, Brossier, Jean-Pierre, Bassil, Joachim, Clavel, Sylvaine, Luyer, Bernard Le, Bougnères, Pierre, Labay, Françoise, Guemas, Isabelle, Weill, Jacques, Cappoen, Jean-Pierre, Nadalon, Sylvie, Lienhardt-Roussie, Anne, Paoli, Anne, Kerouedan, Claudie, Yollin, Edwige, Nicolino, Marc, Simonin, Gilbert, Cohen, Jacques, Atlan, Catherine, Tamboura, Agnès, Dubourg, Hervé, Marie-Laure Pignol, Talon, Philippe, Jellimann, Stéphanie, Chaillous, Lucy, Baron, Sabine, Marie-Noëlle Bortoluzzi, Baechler, Elisabeth, Salet, Randa, Zelinsky-Gurung, Ariane, Dallavale, Fabienne, Larger, Etienne, Laloi-Michelin, Marie, Jean-François Gautier, Guérin, Bénédicte, Oilleau, Laure, Pantalone, Laetitia, Lukas, Céline, Guilhem, Isabelle, Kerdanet, Marc De, Marie-Claire Wielickzo, Priou-Guesdon, Mélanie, Richard, Odile, Kurtz, François, Laisney, Norbert, Ancelle, Déborah, Parlier, Guilhem, Boniface, Catherine, Bockel, Dominique, Dufillot, Denis, Razafimahefa, Berthe, Gourdy, Pierre, Lecomte, Pierre, Pepin-Donat, Myriam, Marie-Emmanuelle Combes-Moukhovsky, Zymmermann, Brigitte, Raoulx, Marina, and Dumont, Anne

Abstract

The questionnaire used in the current study. (PDF 620 kb)

Published
2016
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3. Additional file 3: of Association of environmental markers with childhood type 1 diabetes mellitus revealed by a long questionnaire on early life exposures and lifestyle in a case–control study

Author

F. Balazard, S. Le Fur, S. Valtat, A. Valleron, P. Bougnères, Thevenieau, Dominique, Chatel, Corinne, Desailloud, Rachel, Bony-Trifunovic, Hélène, Pierre-Henri Ducluzeau, Coutant, Régis, Caudrelier, Sophie, Pambou, Armelle, Dubosclard, Emmanuelle, Joubert, Florence, Jan, Philippe, Marcoux, Estelle, Bertrand, Anne-Marie, Mignot, Brigitte, Penformis, Alfred, Stuckens, Chantal, Piquemal, Régis, Barat, Pascal, Rigalleau, Vincent, Stheneur, Chantal, Fournier, Sylviane, Kerlan, Véronique, Metz, Chantal, Fargeot-Espaliat, Anne, Reznic, Yves, Olivier, Frédérique, Gueorguieva, Iva, Monier, Arnaud, Radet, Catherine, Gajdos, Vincent, Terral, Daniel, Vervel, Christine, Bendifallah, Djamel, Signor, Candace, Dervaux, Daniel, Abdelkader Benmahammed, Guy-André Loeuille, Popelard, Françoise, Guillou, Agnès, Pierre-Yves Benhamou, Khoury, Jamil, Brossier, Jean-Pierre, Bassil, Joachim, Clavel, Sylvaine, Luyer, Bernard Le, Bougnères, Pierre, Labay, Françoise, Guemas, Isabelle, Weill, Jacques, Cappoen, Jean-Pierre, Nadalon, Sylvie, Lienhardt-Roussie, Anne, Paoli, Anne, Kerouedan, Claudie, Yollin, Edwige, Nicolino, Marc, Simonin, Gilbert, Cohen, Jacques, Atlan, Catherine, Tamboura, Agnès, Dubourg, Hervé, Marie-Laure Pignol, Talon, Philippe, Jellimann, Stéphanie, Chaillous, Lucy, Baron, Sabine, Marie-Noëlle Bortoluzzi, Baechler, Elisabeth, Salet, Randa, Zelinsky-Gurung, Ariane, Dallavale, Fabienne, Larger, Etienne, Laloi-Michelin, Marie, Jean-François Gautier, Guérin, Bénédicte, Oilleau, Laure, Pantalone, Laetitia, Lukas, Céline, Guilhem, Isabelle, Kerdanet, Marc De, Marie-Claire Wielickzo, Priou-Guesdon, Mélanie, Richard, Odile, Kurtz, François, Laisney, Norbert, Ancelle, Déborah, Parlier, Guilhem, Boniface, Catherine, Bockel, Dominique, Dufillot, Denis, Razafimahefa, Berthe, Gourdy, Pierre, Lecomte, Pierre, Pepin-Donat, Myriam, Marie-Emmanuelle Combes-Moukhovsky, Zymmermann, Brigitte, Raoulx, Marina, and Dumont, Anne

Abstract

Additional analysis supporting the exclusion for primary school mistake and exploring further age-related bias. (PDF 5474 kb)

Published
2016
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4. Association of environmental markers with childhood type 1 diabetes mellitus revealed by a long questionnaire on early life exposures and lifestyle in a case-control study.

Author

Balazard F, Le Fur S, Valtat S, Valleron AJ, Bougnères P, Thevenieau D, Chatel CF, Desailloud R, Bony-Trifunovic H, Ducluzeau PH, Coutant R, Caudrelier S, Pambou A, Dubosclard E, Joubert F, Jan P, Marcoux E, Bertrand AM, Mignot B, Penformis A, Stuckens C, Piquemal R, Barat P, Rigalleau V, Stheneur C, Fournier S, Kerlan V, Metz C, Fargeot-Espaliat A, Reznic Y, Olivier F, Gueorguieva I, Monier A, Radet C, Gajdos V, Terral D, Vervel C, Bendifallah D, Signor CB, Dervaux D, Benmahammed A, Loeuille GA, Popelard F, Guillou A, Benhamou PY, Khoury J, Brossier JP, Bassil J, Clavel S, Le Luyer B, Bougnères P, Labay F, Guemas I, Weill J, Cappoen JP, Nadalon S, Lienhardt-Roussie A, Paoli A, Kerouedan C, Yollin E, Nicolino M, Simonin G, Cohen J, Atlan C, Tamboura A, Dubourg H, Pignol ML, Talon P, Jellimann S, Chaillous L, Baron S, Bortoluzzi MN, Baechler E, Salet R, Zelinsky-Gurung A, Dallavale F, Larger E, Laloi-Michelin M, Gautier JF, Guérin B, Oilleau L, Pantalone L, Lukas C, Guilhem I, De Kerdanet M, Wielickzo MC, Priou-Guesdon M, Richard O, Kurtz F, Laisney N, Ancelle D, Parlier G, Boniface C, Bockel DP, Dufillot D, Razafimahefa B, Gourdy P, Lecomte P, Pepin-Donat M, Combes-Moukhovsky ME, Zymmermann B, Raoulx M, and Dumont AG

Abstract

Background: The incidence of childhood type 1 diabetes (T1D) incidence is rising in many countries, supposedly because of changing environmental factors, which are yet largely unknown. The purpose of the study was to unravel environmental markers associated with T1D., Methods: Cases were children with T1D from the French Isis-Diab cohort. Controls were schoolmates or friends of the patients. Parents were asked to fill a 845-item questionnaire investigating the child's environment before diagnosis. The analysis took into account the matching between cases and controls. A second analysis used propensity score methods., Results: We found a negative association of several lifestyle variables, gastroenteritis episodes, dental hygiene, hazelnut cocoa spread consumption, wasp and bee stings with T1D, consumption of vegetables from a farm and death of a pet by old age., Conclusions: The found statistical association of new environmental markers with T1D calls for replication in other cohorts and investigation of new environmental areas., Trial Registration: Clinical-Trial.gov NCT02212522 . Registered August 6, 2014.

Published
2016
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