1. Cross‐polarization optical coherence tomographic assessment of in situ simulated erosive tooth wear
- Author
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Romero, Maria Jacinta Rosario H, Bezerra, Savio JC, Fried, Daniel, Yang, Vincent, Lippert, Frank, Eckert, George J, Zero, Domenick T, and Hara, Anderson Takeo
- Subjects
Analytical Chemistry ,Medicinal and Biomolecular Chemistry ,Chemical Sciences ,Clinical Research ,Bioengineering ,Cross-Over Studies ,Humans ,Tomography ,Optical Coherence ,Tooth Erosion ,Tooth Wear ,X-Ray Microtomography ,dental erosion ,enamel ,erosive tooth wear ,optical coherence tomography ,Optical Physics ,Medical Biotechnology ,Optoelectronics & Photonics ,Analytical chemistry ,Medicinal and biomolecular chemistry - Abstract
This clinical study tested cross-polarization optical coherence tomography (CP-OCT) monitoring of erosive tooth wear (ETW). Twenty participants completed a 14-day/arm, 3-arm crossover study simulating different ETW severities. Participants received two enamel specimens (per arm) and were randomized to: severe (s-ETW, lemon juice/pH:2.5/4.25%wt/vol citric acid), moderate (m-ETW, grapefruit juice/pH:3.5/1.03%wt/vol citric acid), and non-ETW (water). Enamel thickness was measured with CP-OCT (day[D] 0, 7, 14) and micro-computed tomography (μ-CT; D14). Enamel surface loss was determined with CP-OCT and optical profilometry (OP; D7, D14). CP-OCT showed higher enamel surface loss for D14 than D7 for m-ETW (P = .009) and s-ETW (P = .040) and differentiated severity at D14 (s-ETW > non-ETW, P = .027). OP was able to differentiate surface loss between days (D7
- Published
- 2021