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Colchicine, one of the oldest medications still in use, is a relatively inexpensive and well-tolerated agent with a documented role in a range of inflammatory diseases, such as gout, Behchet’s disease and pericarditis. In recent years, different clinical trials also tested colchicine in the management of cardiovascular conditions and demonstrated favorable results. The aim of this literature review is to evaluate the prospective use of colchicine instead of aspirin as double-antiplatelet therapy (DAPT) after percutaneous coronary interventions in patients with acute coronary syndrome.

Primary cardiac tumors are rare and most frequently benign. The most common primary cardiac tumors are myxomas. Early clinical symptoms can resemble different cardiovascular and systemic diseases. The heterogeneity in their presentation is due to the different localization of myxomas and different structural characteristics. In most cases an echocardiographic examination is sufficient to establish the diagnosis. Early diagnosis and referral for surgery can prevent debilitating complications. The definitive treatment is surgical extirpation of the tumor. We present two clinical cases of cardiac myxomas, the first of which was localized in the left atrium and had villous characteristics, presenting mainly with embolic events. In the second case, the tumor formation was in the right atrium, solid in nature, causing angina and dyspnea.

Left ventricle pseudoaneurysm is a rare but serious complication, most often secondary to myocardial infarction. It is associated with high mortality due to a significant risk of rupture. We present a case of a patient with a large basal pseudoaneurysm of the lateral wall of the left ventricle. The pseudoaneurysm is discovered from a chest radiography performed after a COVID-19 infection. The diagnosis is confirmed by echocardiography and ventriculography. The patient underwent surgical treatment by endoventricular patch plasty – Dor procedure. The patient in our case lacked the typical symptoms and ECG features, furthermore he had no history of myocardial infarction, cardiac surgery, trauma or endocarditis.