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7 results on '"R. Dalzini"'

1. [Immunohistochemistry and in situ hybridization techniques in the study of 75 patients with HPV-induced lesions of the genitalia]

Author

L, Massone, C, Gambini, S, Casazza, S, Borghi, V, Isola, G, Solari, R, Dalzini, and M, Canepa

Subjects
Male, Capsid, Vulvar Neoplasms, Condylomata Acuminata, Humans, Uterine Cervical Neoplasms, Female, DNA Probes, HPV, Anus Neoplasms, Antigens, Viral, Immunohistochemistry, Papillomaviridae, Penile Neoplasms
Abstract

Seventy-five patients with anogenital warts were biopsied in the Center for Sexually Transmitted Disease of Galliera Hospital (Genoa). Bioptic specimens were processed for histologic examination, immunohistochemistry using polyclonal antibodies against HPV capsid common antigens and in situ hybridization using HPV 6/11, 16/18, 31/35/51 DNA probes. The aim of the study was to detect patients positive for HPV 16/18, 31/35/51 DNA probes. These HPV types have a higher oncogenic potential and patients with lesions harbouring them are considered to be at risk for progression to malignancy. These patients should be followed up carefully and periodically for early detection of new lesions and neoplastic transformation.

Published
1990

5. [Immunohistochemistry and in situ hybridization techniques in the study of 75 patients with HPV-induced lesions of the genitalia].

Author

Massone L, Gambini C, Casazza S, Borghi S, Isola V, Solari G, Dalzini R, and Canepa M

Subjects
Antigens, Viral analysis, Capsid immunology, DNA Probes, HPV, Female, Humans, Immunohistochemistry, Male, Papillomaviridae immunology, Anus Neoplasms diagnosis, Condylomata Acuminata diagnosis, Penile Neoplasms diagnosis, Uterine Cervical Neoplasms diagnosis, Vulvar Neoplasms diagnosis
Abstract

Seventy-five patients with anogenital warts were biopsied in the Center for Sexually Transmitted Disease of Galliera Hospital (Genoa). Bioptic specimens were processed for histologic examination, immunohistochemistry using polyclonal antibodies against HPV capsid common antigens and in situ hybridization using HPV 6/11, 16/18, 31/35/51 DNA probes. The aim of the study was to detect patients positive for HPV 16/18, 31/35/51 DNA probes. These HPV types have a higher oncogenic potential and patients with lesions harbouring them are considered to be at risk for progression to malignancy. These patients should be followed up carefully and periodically for early detection of new lesions and neoplastic transformation.

Published
1990

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