Search

Your search keyword '"R. A., Batista"' showing total 233 results
Start Over Author "R. A., Batista"
233 results on '"R. A., Batista"'

1. A Novel Polymerase Chain Reaction (PCR)-Based Method for the Rapid Identification of Chrysodeixis includens and Rachiplusia nu

Author

Guilherme A. Gotardi, Natália R. F. Batista, Tamylin Kaori Ishizuka, Luiz H. Marques, Mário H. Dal Pogetto, Amit Sethi, Mark L. Dahmer, and Timothy Nowatzki

Subjects
Plusiinae, soybean looper, sunflower looper, mtCOI, PCR, molecular identification, Science
Abstract

Chrysodeixis includens and Rachiplusia nu are two species belonging to the Plusiinae subfamily within the Noctuidae family. Due to their morphological similarity, the identification of their larvae is difficult and time-consuming. A rapid and accurate identification of these two species is essential for their management as these species exhibit differential susceptibilities to insecticides and crops engineered to express Bacillus thuringiensis (Bt) proteins, and a molecular tool can easily provide this differentiation. Currently, molecular analysis can identify these species through genetic sequencing, an expensive and time-consuming process. In our study, after sequencing part of the mtDNA cytochrome c oxidase I (COI) gene and based on the differences found in the gene of each species, a set of species-specific primers was developed: one reverse primer common to both species and two forward primers, specific to each species, amplifying fragments of 199 base pairs (bp) for C. includens and 299 bp for R. nu. Our results indicate that the primers were specific for these species, enabling the identification of individuals directly through agarose gel. The new methodology proved to be accurate, rapid, and reliable for the correct identification of these two species of loopers.

Published
2024
Full Text
View/download PDF

2. Effects of Nicotine on the Thermodynamics and Phase Coexistence of Pulmonary Surfactant Model Membranes

Author

Fadi S. S. Magalhães, Ernanni D. Vieira, Mariana R. B. Batista, Antonio J. Costa-Filho, and Luis G. M. Basso

Subjects
nicotine, pulmonary surfactant, phase coexistence, ESR, DSC, van’t Hoff, Chemical technology, TP1-1185, Chemical engineering, TP155-156
Abstract

Phase separation is essential for membrane function, and alterations in phase coexistence by membrane-interacting molecules, such as nicotine, can impair membrane stability. With the increasing use of e-cigarettes, concerns have arisen about the impact of nicotine on pulmonary surfactants. Here, we used differential scanning calorimetry (DSC), molecular dynamics (MD) simulations, and electron spin resonance (ESR) to examine nicotine’s effect on the phase coexistence of two surfactant models: pure DPPC and a DPPC/POPC/POPG mixture. Our DSC analysis revealed that nicotine interacts with both membranes, increasing enthalpy and entropy change during the phase transition. ESR revealed that nicotine affects membrane fluidity and packing of DPPC more effectively than the ternary mixture, especially near the surface. MD simulations showed that neutral nicotine resides in the mid-plane, while protonated nicotine remains near the surface. Nicotine binding to the membranes is dynamic, switching between bound and unbound states. Analysis via ESR/van’t Hoff method revealed changes in the thermodynamics of phase coexistence, yielding distinct non-linear behavior. Nicotine altered the temperature dependence of the free energy, modifying the thermodynamic driving forces and the balance of non-covalent lipid interactions. These findings provide new insights into how nicotine influences pulmonary surfactant model membranes, with potential implications for surfactant function.

Published
2024
Full Text
View/download PDF

3. Repulsive Casimir force in stationary axisymmetric spacetimes

Author

V. De La Hoz-Coronell, A. E. Gonçalves, M. C. Baldiotti, and R. C. Batista

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We study the influence of stationary axisymmetric spacetimes on Casimir energy. We consider a massive scalar field and analyze its dependence on the apparatus orientation with respect to the dragging direction associated with such spaces. We show that, for an apparatus orientation not considered before in the literature, the Casimir energy can change its sign, producing a repulsive force. As applications, we analyze two specific metrics: one associated with a linear motion of a cylinder and a circular equatorial motion around a gravitational source described by Kerr geometry.

Published
2022
Full Text
View/download PDF

4. The energy spectrum of cosmic rays beyond the turn-down around $$\varvec{10^{17}}$$ 10 17 eV as measured with the surface detector of the Pierre Auger Observatory

Author

P. Abreu, M. Aglietta, J. M. Albury, I. Allekotte, A. Almela, J. Alvarez-Muñiz, R. Alves Batista, G. A. Anastasi, L. Anchordoqui, B. Andrada, S. Andringa, C. Aramo, P. R. Araújo Ferreira, J. C. Arteaga Velázquez, H. Asorey, P. Assis, G. Avila, A. M. Badescu, A. Bakalova, A. Balaceanu, F. Barbato, R. J. Barreira Luz, K. H. Becker, J. A. Bellido, C. Berat, M. E. Bertaina, X. Bertou, P. L. Biermann, P. Billoir, V. Binet, K. Bismark, T. Bister, J. Biteau, J. Blazek, C. Bleve, M. Boháčová, D. Boncioli, C. Bonifazi, L. Bonneau Arbeletche, N. Borodai, A. M. Botti, J. Brack, T. Bretz, P. G. Brichetto Orchera, F. L. Briechle, P. Buchholz, A. Bueno, S. Buitink, M. Buscemi, M. Büsken, K. S. Caballero-Mora, L. Caccianiga, F. Canfora, I. Caracas, J. M. Carceller, R. Caruso, A. Castellina, F. Catalani, G. Cataldi, L. Cazon, M. Cerda, J. A. Chinellato, J. Chudoba, L. Chytka, R. W. Clay, A. C. Cobos Cerutti, R. Colalillo, A. Coleman, M. R. Coluccia, R. Conceição, A. Condorelli, G. Consolati, F. Contreras, F. Convenga, D. Correia dos Santos, C. E. Covault, S. Dasso, K. Daumiller, B. R. Dawson, J. A. Day, R. M. de Almeida, J. de Jesús, S. J. de Jong, G. De Mauro, J. R. T. de Mello Neto, I. De Mitri, J. de Oliveira, D. de Oliveira Franco, F. de Palma, V. de Souza, E. De Vito, M. del Río, O. Deligny, A. Di Matteo, C. Dobrigkeit, J. C. D’Olivo, L. M. Domingues Mendes, R. C. dos Anjos, D. dos Santos, M. T. Dova, J. Ebr, R. Engel, I. Epicoco, M. Erdmann, C. O. Escobar, A. Etchegoyen, H. Falcke, J. Farmer, G. Farrar, A. C. Fauth, N. Fazzini, F. Feldbusch, F. Fenu, B. Fick, J. M. Figueira, A. Filipčič, T. Fitoussi, T. Fodran, M. M. Freire, T. Fujii, A. Fuster, C. Galea, C. Galelli, B. García, A. L. Garcia Vegas, H. Gemmeke, F. Gesualdi, A. Gherghel-Lascu, P. L. Ghia, U. Giaccari, M. Giammarchi, J. Glombitza, F. Gobbi, F. Gollan, G. Golup, M. Gómez Berisso, P. F. Gómez Vitale, J. P. Gongora, J. M. González, N. González, I. Goos, D. Góra, A. Gorgi, M. Gottowik, T. D. Grubb, F. Guarino, G. P. Guedes, E. Guido, S. Hahn, P. Hamal, M. R. Hampel, P. Hansen, D. Harari, V. M. Harvey, A. Haungs, T. Hebbeker, D. Heck, G. C. Hill, C. Hojvat, J. R. Hörandel, P. Horvath, M. Hrabovský, T. Huege, A. Insolia, P. G. Isar, P. Janecek, J. A. Johnsen, J. Jurysek, A. Kääpä, K. H. Kampert, N. Karastathis, B. Keilhauer, J. Kemp, A. Khakurdikar, V. V. Kizakke Covilakam, H. O. Klages, M. Kleifges, J. Kleinfeller, M. Köpke, N. Kunka, B. L. Lago, R. G. Lang, N. Langner, M. A. Leigui de Oliveira, V. Lenok, A. Letessier-Selvon, I. Lhenry-Yvon, D. Lo Presti, L. Lopes, R. López, L. Lu, Q. Luce, J. P. Lundquist, A. Machado Payeras, G. Mancarella, D. Mandat, B. C. Manning, J. Manshanden, P. Mantsch, S. Marafico, A. G. Mariazzi, I. C. Mariş, G. Marsella, D. Martello, S. Martinelli, H. Martinez, O. Martínez Bravo, M. Mastrodicasa, H. J. Mathes, J. Matthews, G. Matthiae, E. Mayotte, P. O. Mazur, G. Medina-Tanco, D. Melo, A. Menshikov, K.-D. Merenda, S. Michal, M. I. Micheletti, L. Miramonti, D. Mockler, S. Mollerach, F. Montanet, C. Morello, M. Mostafá, A. L. Müller, M. A. Muller, K. Mulrey, R. Mussa, M. Muzio, W. M. Namasaka, A. Nasr-Esfahani, L. Nellen, M. Niculescu-Oglinzanu, M. Niechciol, D. Nitz, D. Nosek, V. Novotny, L. Nožka, A. Nucita, L. A. Núñez, M. Palatka, J. Pallotta, P. Papenbreer, G. Parente, A. Parra, J. Pawlowsky, M. Pech, F. Pedreira, J. Pȩkala, R. Pelayo, J. Peña-Rodriguez, E. E. Pereira Martins, J. Perez Armand, C. Pérez Bertolli, M. Perlin, L. Perrone, S. Petrera, T. Pierog, M. Pimenta, V. Pirronello, M. Platino, B. Pont, M. Pothast, P. Privitera, M. Prouza, A. Puyleart, S. Querchfeld, J. Rautenberg, D. Ravignani, M. Reininghaus, J. Ridky, F. Riehn, M. Risse, V. Rizi, W. Rodrigues de Carvalho, J. Rodriguez Rojo, M. J. Roncoroni, M. Roth, E. Roulet, A. C. Rovero, P. Ruehl, S. J. Saffi, A. Saftoiu, F. Salamida, H. Salazar, G. Salina, J. D. Sanabria Gomez, F. Sánchez, E. M. Santos, E. Santos, F. Sarazin, R. Sarmento, C. Sarmiento-Cano, R. Sato, P. Savina, C. M. Schäfer, V. Scherini, H. Schieler, M. Schimassek, M. Schimp, F. Schlüter, D. Schmidt, O. Scholten, P. Schovánek, F. G. Schröder, S. Schröder, J. Schulte, A. Schulz, S. J. Sciutto, M. Scornavacche, A. Segreto, S. Sehgal, R. C. Shellard, G. Sigl, G. Silli, O. Sima, R. Šmída, P. Sommers, J. F. Soriano, J. Souchard, R. Squartini, M. Stadelmaier, D. Stanca, S. Stanič, J. Stasielak, P. Stassi, A. Streich, M. Suárez-Durán, T. Sudholz, T. Suomijärvi, A. D. Supanitsky, Z. Szadkowski, A. Tapia, C. Taricco, C. Timmermans, O. Tkachenko, P. Tobiska, C. J. Todero Peixoto, B. Tomé, Z. Torrès, A. Travaini, P. Travnicek, C. Trimarelli, M. Tueros, R. Ulrich, M. Unger, L. Vaclavek, M. Vacula, J. F. Valdés Galicia, L. Valore, E. Varela, A. Vásquez-Ramírez, D. Veberič, C. Ventura, I. D. Vergara Quispe, V. Verzi, J. Vicha, J. Vink, S. Vorobiov, H. Wahlberg, C. Watanabe, A. A. Watson, M. Weber, A. Weindl, L. Wiencke, H. Wilczyński, M. Wirtz, D. Wittkowski, B. Wundheiler, A. Yushkov, O. Zapparrata, E. Zas, D. Zavrtanik, M. Zavrtanik, L. Zehrer, and Pierre Auger Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We present a measurement of the cosmic-ray spectrum above 100 PeV using the part of the surface detector of the Pierre Auger Observatory that has a spacing of 750 m. An inflection of the spectrum is observed, confirming the presence of the so-called second-knee feature. The spectrum is then combined with that of the 1500 m array to produce a single measurement of the flux, linking this spectral feature with the three additional breaks at the highest energies. The combined spectrum, with an energy scale set calorimetrically via fluorescence telescopes and using a single detector type, results in the most statistically and systematically precise measurement of spectral breaks yet obtained. These measurements are critical for furthering our understanding of the highest energy cosmic rays.

Published
2021
Full Text
View/download PDF

6. Karyotype characterization and evolution of chromosome number in Cactaceae with special emphasis on subfamily Cactoideae

Author

Juliana P. Castro, Ana Paula Moraes, Mark W. Chase, Angeline M. S. Santos, Fabiane R. C. Batista, and Leonardo P. Felix

Subjects
base chromosome number, CMA/DAPI, dysploidy, heterochromatin, polyploidy, rDNA, Botany, QK1-989
Abstract

ABSTRACT Cactaceae species are karyotypically well-known with x = 11 and chromosome number variation due mainly to polyploidization. However, both assumptions are based on descriptive observations without taking an evolutionary framework of Cactaceae into account. Aiming to confirm these hypotheses in an evolutionary context, we obtained chromosome numbers for 20 species of Cactoideae, performed an extensive review of chromosome number for the family, and analyzed these data using a phylogenetic approach. The karyotypes presented here were characterized by CMA/DAPI banding, and for six species 5S and 45S rDNA sites were located. Our data, along with a survey of the literature, reinforce the long-standing hypothesis of a x = 11 as the base chromosome number for Cactaceae. They also reinforce the relevance of polyploidy in karyotype evolution of cacti, although polyploidy was important just after the diversification of subfamilies Maihuenioideae and Pereskioideae. Despite the homogeneous chromosome complements observed among cacti, chromosome banding and FISH techniques revealed informative characteristics, allowing the identification of chromosome synapomorphies, such as proximal CMA+ bands in Melocactus and proximal 5S rDNA in Pilosocereus, indicating the taxonomic potential of chromosome characterization in cacti.

Published
2019
Full Text
View/download PDF

7. Chemical composition and in vitro inhibitory effects of essential oils from fruit peel of three Citrus species and limonene on mycelial growth of Sclerotinia sclerotiorum

Author

A. L. B. Dias, W. C. Sousa, H. R. F. Batista, C. C. F. Alves, E. L. Souchie, F. G. Silva, P. S. Pereira, E. M. Sperandio, C. M. Cazal, M. R. Forim, and M. L. D. Miranda

Subjects
Citrus reticulata, Citrus sinensis, Citrus deliciosa, white rot, limonene, white mold, Science, Biology (General), QH301-705.5, Zoology, QL1-991, Botany, QK1-989
Abstract

Abstract Essential oils (EO) from aromatic and medicinal plants generally perform a diverse range of biological activities because they have several active constituents that work in different mechanisms of action. EO from Citrus peel have an impressive range of food and medicinal uses, besides other applications. EO from Citrus reticulata, C. sinensis and C. deliciosa were extracted from fruit peel and analyzed by GC-MS. The major constituent of EO under evaluation was limonene, whose concentrations were 98.54%, 91.65% and 91.27% for C. sinensis, C. reticulata and C. deliciosa, respectively. The highest potential of inhibition of mycelial growth was observed when the oil dose was 300 μL. Citrus oils inhibited fungus growth in 82.91% (C. deliciosa), 65.82% (C. sinensis) and 63.46% (C. reticulata). Anti-Sclerotinia sclerotiorum activity of 90% pure limonene and at different doses (20, 50, 100, 200 and 300 μL) was also investigated. This monoterpene showed to be highly active by inhibiting 100% fungus growth even at 200 and 300 μL doses. This is the first report of the in vitro inhibitory effect of natural products from these three Citrus species and its results show that there is good prospect of using them experimentally to control S. sclerotiorum, in both greenhouse and field conditions.

Published
2019
Full Text
View/download PDF

8. PPARα Gene Is Involved in Body Composition Variation in Response to an Aerobic Training Program in Overweight/Obese

Author

Glêbia A. Cardoso, Mateus D. Ribeiro, Bruno R. V. Sousa, Yohanna de Oliveira, Klécia F. Sena, Joane R. E. Batista, Antônio E. M. Almeida, João M. Filho, Raquel S. B. Silva, Darlene C. Persuhn, and Alexandre S. Silva

Subjects
Biology (General), QH301-705.5
Abstract

The objective of this study was to investigate the relationship of the polymorphism in Intron 7 G/C (rs 4253778) of the peroxisome proliferator-activated receptor alpha (PPARα) gene with the magnitude of changes in the body composition of an overweight and obese population that underwent an aerobic training program. Fifty-eight previously inactive men and women, body mass index (BMI) 31.5±2.8 kg/m2, 46.5% (n=27) genotyped as CC genotype and 53.5% (n=31) as CA+AA, underwent a 12-week aerobic training (walking/running). Aerobic capacity (ergospirometry), body composition (DXA), and nutritional assessment were made before and 48 h after the experimental protocol. Two-way ANOVA, chi-square test, and logistic regression were used (p

Published
2021
Full Text
View/download PDF

10. Extragalactic observatory science with the ASTRI mini-array at the Observatorio del Teide

Author

F.G. Saturni, C.H.E. Arcaro, B. Balmaverde, J. Becerra González, A. Caccianiga, M. Capalbi, A. Lamastra, S. Lombardi, F. Lucarelli, R. Alves Batista, L.A. Antonelli, E.M. de Gouveia Dal Pino, R. Della Ceca, J.G. Green, A. Pagliaro, C. Righi, F. Tavecchio, S. Vercellone, A. Wolter, E. Amato, C. Bigongiari, M. Böttcher, G. Brunetti, P. Bruno, A. Bulgarelli, M. Cardillo, V. Conforti, A. Costa, G. Cusumano, V. Fioretti, S. Germani, A. Ghedina, F. Gianotti, V. Giordano, A. Giuliani, F. Incardona, A. La Barbera, G. Leto, F. Longo, G. Morlino, B. Olmi, N. Parmiggiani, P. Romano, G. Romeo, A. Stamerra, G. Tagliaferri, V. Testa, G. Tosti, P.A. Caraveo, and G. Pareschi

Subjects
High Energy Astrophysical Phenomena (astro-ph.HE), Space and Planetary Science, Gamma ray, FOS: Physical sciences, Cherenkov, Astronomy and Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics, ASTRI Mini Array, Instrumentation and Methods for Astrophysics (astro-ph.IM), Cherenkov, Extragalactic, Gamma ray, ASTRI Mini Array, Extragalactic
Abstract

The ASTRI Mini-Array is a next-generation system of nine imaging atmospheric Cherenkov telescopes that is going to be built at the Observatorio del Teide site. After a first phase, in which the instrument will be operated as an experiment prioritizing a schedule of primary science cases, an observatory phase is foreseen in which other significant targets will be pointed. We focus on the observational feasibility of extragalactic sources and on astrophysical processes that best complement and expand the ASTRI Mini-Array core science, presenting the most relevant examples that are at reach of detection over long-term time scales and whose observation can provide breakthrough achievements in the very-high energy extragalactic science. Such examples cover a wide range of $\gamma$-ray emitters, including the study of AGN low states in the multi-TeV energy range, the possible detection of Seyfert galaxies with long exposures and the searches of dark matter lines above 10 TeV. Simulations of the presented objects show that the instrument performance will be competitive at multi-TeV energies with respect to current arrays of Cherenkov telescopes., Comment: 27 pages, 10 figures, 7 tables, published on JHEAp

Published
2022
Full Text
View/download PDF

12. Well-dispersed titanium dioxide and silver nanoparticles on external and internal surfaces of asymmetric alumina hollow fibers for enhanced chromium (VI) photoreductions

Author

Igor G. F. Costa, Stella R. F. L. Ribeiro, Lucas L. Nascimento, Antonio Otavio T. Patrocinio, Vicelma L. Cardoso, Fabiana R. X. Batista, and Miria H. M. Reis

Subjects
Health, Toxicology and Mutagenesis, Environmental Chemistry, General Medicine, Pollution
Abstract

Silver (Ag)-decorated titanium dioxide (TiO2) catalysts were produced under ultrasound irradiation at different loadings of Ag nanoparticles (from 5 to 50 wt%). Then, the catalysts were supported on internal and external surfaces of alumina hollow fibers with asymmetric pore size distribution. The produced catalysts were considered for Cr(VI) photoreductions. The ultrasound-assisted process potentialized the distribution of Ag nanoparticles on the TiO2 surface. The loading of Ag nanoparticles at concentrations greater than 5 wt% was necessary to improve the TiO2 activity for Cr(VI) photoreduction. The loading of Ag nanoparticles at 30 wt% improved the Cr(VI) photoreduction of the single TiO2 catalyst from 40.49 ± 0.98 to 55.00 ± 0.83% after 180 min of reaction. Suspended and supported Ag-decorated TiO2 catalysts achieved total Cr(VI) photoreduction after 21 h of reaction. The adjusted reaction rate constant with the externally supported Ag-TiO2 catalyst was 3.57x10-3 ± 0.18 x10-3 min-1. Similar reaction rate constants were achieved with suspended and internally supported catalysts (approximately 2.70x10-3 min-1). After 10 sequential reuses, all catalysts presented similar Cr(VI) photoreductions of approximately 66%. Nevertheless, the use of the externally supported catalyst is suggested for Cr(VI) photoreductions due to its superior catalyst activity at least in the first reuse cycles.

Published
2023
Full Text
View/download PDF

13. Sensitivity of the Cherenkov Telescope Array to TeV photon emission from the Large Magellanic Cloud

Author

A Acharyya, R Adam, A Aguasca-Cabot, I Agudo, A Aguirre-Santaella, J Alfaro, R Aloisio, R Alves Batista, E Amato, E O Angüner, C Aramo, C Arcaro, K Asano, J Aschersleben, H Ashkar, M Backes, A Baktash, C Balazs, M Balbo, J Ballet, A Bamba, A Baquero Larriva, V Barbosa Martins, U Barres de Almeida, J A Barrio, D Bastieri, P Batista, I Batkovic, J R Baxter, J Becerra González, J Becker Tjus, W Benbow, E Bernardini, M I Bernardos Martín, J Bernete Medrano, A Berti, B Bertucci, V Beshley, P Bhattacharjee, S Bhattacharyya, C Bigongiari, A Biland, E Bissaldi, F Bocchino, P Bordas, J Borkowski, E Bottacini, M Böttcher, F Bradascio, A M Brown, A Bulgarelli, L Burmistrov, S Caroff, A Carosi, E Carquín, S Casanova, E Cascone, F Cassol, M Cerruti, P Chadwick, S Chaty, A Chen, A Chiavassa, L Chytka, V Conforti, J Cortina, A Costa, H Costantini, G Cotter, S Crestan, P Cristofari, F D’Ammando, M Dalchenko, F Dazzi, A De Angelis, V De Caprio, E M de Gouveia Dal Pino, D De Martino, M de Naurois, V de Souza, M V del Valle, A G Delgado Giler, C Delgado, D della Volpe, D Depaoli, T Di Girolamo, A Di Piano, F Di Pierro, R Di Tria, L Di Venere, S Diebold, M Doro, D Dumora, V V Dwarkadas, C Eckner, K Egberts, G Emery, J Escudero, D Falceta-Goncalves, E Fedorova, S Fegan, Q Feng, D Ferenc, G Ferrand, E Fiandrini, M Filipovic, V Fioretti, L Foffano, G Fontaine, Y Fukui, D Gaggero, G Galanti, G Galaz, S Gallozzi, V Gammaldi, M Garczarczyk, C Gasbarra, D Gasparrini, A Ghalumyan, M Giarrusso, G Giavitto, N Giglietto, F Giordano, A Giuliani, J-F Glicenstein, P Goldoni, J Goulart Coelho, J Granot, D Green, J G Green, M-H Grondin, O Gueta, D Hadasch, P Hamal, T Hassan, K Hayashi, M Heller, S Hernández Cadena, N Hiroshima, B Hnatyk, R Hnatyk, W Hofmann, J Holder, M Holler, D Horan, P Horvath, M Hrabovsky, M Hütten, M Iarlori, T Inada, F Incardona, S Inoue, F Iocco, M Jamrozy, W Jin, I Jung-Richardt, J Juryšek, D Kantzas, V Karas, H Katagiri, D Kerszberg, J Knödlseder, N Komin, P Kornecki, K Kosack, G Kowal, H Kubo, A Lamastra, J Lapington, M Lemoine-Goumard, J-P Lenain, F Leone, G Leto, F Leuschner, E Lindfors, T Lohse, S Lombardi, F Longo, R López-Coto, A López-Oramas, S Loporchio, P L Luque-Escamilla, O Macias, P Majumdar, D Mandat, S Mangano, G Manicò, M Mariotti, P Marquez, G Marsella, J Martí, P Martin, M Martínez, D Mazin, S Menchiari, D M-A Meyer, D Miceli, M Miceli, J Michałowski, A Mitchell, R Moderski, L Mohrmann, M Molero, E Molina, T Montaruli, A Moralejo, D Morcuende, A Morselli, E Moulin, V Moya, R Mukherjee, K Munari, A Muraczewski, S Nagataki, T Nakamori, A Nayak, J Niemiec, M Nievas, M Nikołajuk, K Nishijima, K Noda, D Nosek, B Novosyadlyj, S Nozaki, M Ohishi, S Ohm, A Okumura, B Olmi, R A Ong, M Orienti, R Orito, M Orlandini, E Orlando, S Orlando, M Ostrowski, I Oya, A Pagliaro, M Palatka, F R Pantaleo, R Paoletti, J M Paredes, N Parmiggiani, B Patricelli, M Pech, M Pecimotika, M Persic, O Petruk, E Pierre, E Pietropaolo, G Pirola, M Pohl, E Prandini, C Priyadarshi, G Pühlhofer, M L Pumo, M Punch, F S Queiroz, A Quirrenbach, S Rainò, R Rando, S Razzaque, A Reimer, O Reimer, T Reposeur, M Ribó, T Richtler, J Rico, F Rieger, M Rigoselli, V Rizi, E Roache, G Rodriguez Fernandez, P Romano, G Romeo, J Rosado, A Rosales de Leon, B Rudak, C Rulten, I Sadeh, T Saito, M Sánchez-Conde, H Sano, A Santangelo, R Santos-Lima, S Sarkar, F G Saturni, A Scherer, P Schovanek, F Schussler, U Schwanke, O Sergijenko, M Servillat, H Siejkowski, C Siqueira, S Spencer, A Stamerra, S Stanič, C Steppa, T Stolarczyk, Y Suda, T Tavernier, M Teshima, L Tibaldo, D F Torres, N Tothill, M Vacula, B Vallage, P Vallania, C van Eldik, M Vázquez Acosta, M Vecchi, S Ventura, S Vercellone, A Viana, C F Vigorito, J Vink, V Vitale, V Vodeb, S Vorobiov, T Vuillaume, S J Wagner, R Walter, M White, A Wierzcholska, M Will, R Yamazaki, L Yang, T Yoshikoshi, M Zacharias, G Zaharijas, D Zavrtanik, M Zavrtanik, A A Zdziarski, V I Zhdanov, K Ziętara, M Živec, Joseph Louis LAGRANGE (LAGRANGE), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Leprince-Ringuet (LLR), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Astrophysique Interprétation Modélisation (AIM (UMR7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Galaxies, Etoiles, Physique, Instrumentation (GEPI), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Centre d'Etudes Nucléaires de Bordeaux Gradignan (CENBG), Université Sciences et Technologies - Bordeaux 1 (UB)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy-le-Vieux de Physique Théorique (LAPTH), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), and Cherenkov Telescope Array

Subjects
High Energy Astrophysical Phenomena (astro-ph.HE), photon, emission, acceleration, efficiency, Cherenkov Telescope Array, WIMP, diffusion, FOS: Physical sciences, Astronomy and Astrophysics, suppression, sensitivity, Navarro-Frenk-White profile, dark matter, photon, energy, flux, cosmic radiation, spectrum, energy, high, Space and Planetary Science, cloud, TeV, spectral, galaxy, Astrophysics - High Energy Astrophysical Phenomena, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], nucleus, cosmic radiation
Abstract

A deep survey of the Large Magellanic Cloud at ~0.1-100TeV photon energies with the Cherenkov Telescope Array is planned. We assess the detection prospects based on a model for the emission of the galaxy, comprising the four known TeV emitters, mock populations of sources, and interstellar emission on galactic scales. We also assess the detectability of 30 Doradus and SN 1987A, and the constraints that can be derived on the nature of dark matter. The survey will allow for fine spectral studies of N157B, N132D, LMC P3, and 30 Doradus C, and half a dozen other sources should be revealed, mainly pulsar-powered objects. The remnant from SN 1987A could be detected if it produces cosmic-ray nuclei with a flat power-law spectrum at high energies, or with a steeper index 2.3-2.4 pending a flux increase by a factor >3-4 over ~2015-2035. Large-scale interstellar emission remains mostly out of reach of the survey if its >10GeV spectrum has a soft photon index ~2.7, but degree-scale 0.1-10TeV pion-decay emission could be detected if the cosmic-ray spectrum hardens above >100GeV. The 30 Doradus star-forming region is detectable if acceleration efficiency is on the order of 1-10% of the mechanical luminosity and diffusion is suppressed by two orders of magnitude within, Accepted for publication in MNRAS. Corresponding authors: Pierrick Martin, Maria Isabel Bernardos Martin, Fabio Iocco

Published
2023
Full Text
View/download PDF

14. Ultra high energy cosmic rays The intersection of the Cosmic and Energy Frontiers

Author

A. Coleman, J. Eser, E. Mayotte, F. Sarazin, F.G. Schröder, D. Soldin, T.M. Venters, R. Aloisio, J. Alvarez-Muñiz, R. Alves Batista, D. Bergman, M. Bertaina, L. Caccianiga, O. Deligny, H.P. Dembinski, P.B. Denton, A. di Matteo, N. Globus, J. Glombitza, G. Golup, A. Haungs, J.R. Hörandel, T.R. Jaffe, J.L. Kelley, J.F. Krizmanic, L. Lu, J.N. Matthews, I. Mariş, R. Mussa, F. Oikonomou, T. Pierog, E. Santos, P. Tinyakov, Y. Tsunesada, M. Unger, A. Yushkov, M.G. Albrow, L.A. Anchordoqui, K. Andeen, E. Arnone, D. Barghini, E. Bechtol, J.A. Bellido, M. Casolino, A. Castellina, L. Cazon, R. Conceição, R. Cremonini, H. Dujmovic, R. Engel, G. Farrar, F. Fenu, S. Ferrarese, T. Fujii, D. Gardiol, M. Gritsevich, P. Homola, T. Huege, K.-H. Kampert, D. Kang, E. Kido, P. Klimov, K. Kotera, B. Kozelov, A. Leszczyńska, J. Madsen, L. Marcelli, M. Marisaldi, O. Martineau-Huynh, S. Mayotte, K. Mulrey, K. Murase, M.S. Muzio, S. Ogio, A.V. Olinto, Y. Onel, T. Paul, L. Piotrowski, M. Plum, B. Pont, M. Reininghaus, B. Riedel, F. Riehn, M. Roth, T. Sako, F. Schlüter, D.H. Shoemaker, J. Sidhu, I. Sidelnik, C. Timmermans, O. Tkachenko, D. Veberic, S. Verpoest, V. Verzi, J. Vícha, D. Winn, E. Zas, and M. Zotov

Subjects
High Energy Astrophysical Phenomena (astro-ph.HE), Energy Frontier, Astronomy, Particle physics, FOS: Physical sciences, Astronomy and Astrophysics, Cosmic Frontier, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), Astroparticle Physics, Ultra High Energy Cosmic Rays, Snowmass White Paper, Experimental High Energy Physics, High Energy Physics, Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics, Instrumentation and Methods for Astrophysics (astro-ph.IM)
Abstract

The present white paper is submitted as part of the "Snowmass" process to help inform the long-term plans of the United States Department of Energy and the National Science Foundation for high-energy physics. It summarizes the science questions driving the Ultra-High-Energy Cosmic-Ray (UHECR) community and provides recommendations on the strategy to answer them in the next two decades., Comment: Prepared as a solicited white paper for the 2021 Snowmass process. To be published in the Journal of High Energy Astrophysics. v2: fixed typos in author list. v3: included all community feedback received by July 1st 2022 and added the list of endorsers. v4 is the post-reviewer preprint accepted to Astroparticle Physics vol. 149

Published
2023

17. Changes on physiological parameters of tambaqui (Colossoma macropomum) fed with diets supplemented with Amazonian fruit Camu camu (Myrciaria dubia)

Author

P. H. R. Aride, A. M. Oliveira, R. B. Batista, M. S. Ferreira, J. Pantoja-Lima, D. S. Ladislau, P. D. S. Castro, and A. T. Oliveira

Subjects
Amazônia, Colossoma macropomum, Myrciaria dubia, hematologia, ácido ascórbico, Science, Biology (General), QH301-705.5, Zoology, QL1-991, Botany, QK1-989
Abstract

Abstract The physiological responses of juvenile tambaqui (Colossoma macropomum) fed commercial feed supplemented with different concentrations of camu camu (Myrciaria dubia) were evaluated. The design was completely randomized, with treatments arranged in a factorial design with three proportions of camu camu (15%, 30% and 45%) and a control treatment (100% commercial diet), with four replicates per treatment. A total of 96 tambaqui specimens were used, with a mean initial weight of 11.69 ± 2.68 g and a mean length of 7.06 ± 0.44 cm. After 30 days, hematological parameters, metabolic variables, growth and fish swimming performance were evaluated. The different proportions of camu camu in the diet did not cause significant changes to the tambaqui's hematological parameters during the feeding period, except for hemoglobin (Hb) concentration and mean corpuscular hemoglobin concentration (MCHC) after the 30th day, and hematocrit (Ht) after the swimming stress test, which increased significantly (p < 0.05). The significant increases in metabolic variables, such as cortisol, glucose, proteins and triglycerides, and in hematologic variables after the Ucrit test reflect, respectively, biochemical adaptations for maintenance of the energy mobilization process and a regulatory necessity in tissue oxygen demand during intense exercise. Fish fed 15% and 30% camu camu gained the most weight and achieved the best swimming performance, respectively. The results for camu camu concentrations above 30% suggest a saturation of its intrinsic properties in the diet at this level and a loss of nutrients from the commercial feed replaced by the fruit, reducing productive performance and nutritional assimilation.

Published
2017
Full Text
View/download PDF

18. Contextual and individual inequalities of multimorbidity in Brazilian adults: a cross-sectional national-based study

Author

Bruno P Nunes, Tiago N Munhoz, Sanghamitra Pati, Elaine Thumé, Alexandre D P Chiavegatto Filho, Doralice S Cruz Teixeira, Thaynã R Flores, Fabio A Camargo-Figuera, Luiz A Facchini, and Sandro R Rodrigues Batista

Subjects
Medicine
Abstract

Objectives The study aims to evaluate the magnitude of multimorbidity in Brazilian adults, as well to measure their association with individual and contextual factors stratified by Brazilian states and regions.Methods A national-based cross-sectional study was carried out in 2013 with Brazilian adults. Multimorbidity was evaluated by a list of 22 physical and mental morbidities (based on self-reported medical diagnosis and Patient Health Questionnaire-9 for depression). The outcome was analysed taking ≥2 and ≥3 diseases as cut-off points. Factor analysis (FA) was used to identify disease patterns and multilevel models were used to test association with individual and contextual variables.Results The sample comprised 60 202 individuals. Multimorbidity frequency was 22.2% (95% CI 21.5 to 22.9) for ≥2 morbidities and 10.2% (95% CI 9.7 to 10.7) for ≥3 morbidities. In the multilevel adjusted models, females, older people, those living with a partner and having less schooling presented more multiple diseases. No linear association was found according to wealth index but greater outcome frequency was found in individuals with midrange wealth index. Living in states with higher levels of education and wealthier states was associated with greater multimorbidity. Two patterns of morbidities (cardiometabolic problems and respiratory/mental/muscle–skeletal disorders) explained 92% of total variance. The relationship of disease patterns with individual and contextual variables was similar to the overall multimorbidity, with differences among Brazilian regions.Conclusions In Brazil, at least 19 million adults had multimorbidity. Frequency is similar to that found in other Low and and Middle Income Countries. Contextual and individual social inequalities were observed.

Published
2017
Full Text
View/download PDF

19. Radiogenic heat production in rocks from the Sabinas Basin (northeastern Mexico) determined by in situ gamma radiation measurements

Author

J. A. Batista-Rodríguez, J. Tolentino-Álvarez, R. Y. Batista-Cruz, Y. Almaguer-Carmenates, and F. J. López-Saucedo

Abstract

In situ gamma radiation measurements were performed to calculate the radiogenic heat production of sedimentary and igneous rocks from the Sabinas Basin (northeastern Mexico). The sedimentary rocks include shales, sandstones, and limestones from Cretaceous geological formations. The igneous rocks consist of basalts and granodiorites. The basalts belong to different volcanic fields, and the granodiorites are located in the Candela-Monclova magmatic belt. The analysis of all rocks yielded values of up to 13.4 ppm, 47.3 ppm, and 9.1% for uranium (U), thorium (Th), and potassium (K), respectively, and their radiogenic heat production (RHP) values ranged from 0.11 to 6.42 µWm− 3. The studied rocks were accordingly classified as having a low (− 3), moderate (2–4 µWm− 3), and high (> 4 µWm− 3) RHP. Most studied rocks were characterized by a low heat production, and only 12% of the measurements indicated rocks with moderate and high heat production rates. These latter rocks are represented by clastic sedimentary rocks (shale and sandstone) and granodiorites. The sedimentary rocks, particularly shales, had the highest contents of radioelements and RHP (0.43 to 6.42 µWm− 3). These rocks belong to the Olmos Formation, and their high RHP potential are related to their organic matter and silica contents, and their relationship with deep geological structures. The sandstones of the Pátula Formation also yielded high RHP values (0.72 to 4.73 µWm− 3), linked to their silica contents, feldspar, and micas. The shales and granodiorites showed the highest RHP rates from U and sandstones from Th.

Published
2022
Full Text
View/download PDF

20. Quantum gravity phenomenology at the dawn of the multi-messenger era—A review

Author

A. Addazi, J. Alvarez-Muniz, R. Alves Batista, G. Amelino-Camelia, V. Antonelli, M. Arzano, M. Asorey, J.-L. Atteia, S. Bahamonde, F. Bajardi, A. Ballesteros, B. Baret, D.M. Barreiros, S. Basilakos, D. Benisty, O. Birnholtz, J.J. Blanco-Pillado, D. Blas, J. Bolmont, D. Boncioli, P. Bosso, G. Calcagni, S. Capozziello, J.M. Carmona, S. Cerci, M. Chernyakova, S. Clesse, J.A.B. Coelho, S.M. Colak, J.L. Cortes, S. Das, V. D’Esposito, M. Demirci, M.G. Di Luca, A. di Matteo, D. Dimitrijevic, G. Djordjevic, D. Dominis Prester, A. Eichhorn, J. Ellis, C. Escamilla-Rivera, G. Fabiano, S.A. Franchino-Viñas, A.M. Frassino, D. Frattulillo, S. Funk, A. Fuster, J. Gamboa, A. Gent, L.Á. Gergely, M. Giammarchi, K. Giesel, J.-F. Glicenstein, J. Gracia-Bondía, R. Gracia-Ruiz, G. Gubitosi, E.I. Guendelman, I. Gutierrez-Sagredo, L. Haegel, S. Heefer, A. Held, F.J. Herranz, T. Hinderer, J.I. Illana, A. Ioannisian, P. Jetzer, F.R. Joaquim, K.-H. Kampert, A. Karasu Uysal, T. Katori, N. Kazarian, D. Kerszberg, J. Kowalski-Glikman, S. Kuroyanagi, C. Lämmerzahl, J. Levi Said, S. Liberati, E. Lim, I.P. Lobo, M. López-Moya, G.G. Luciano, M. Manganaro, A. Marcianò, P. Martín-Moruno, Manel Martinez, Mario Martinez, H. Martínez-Huerta, P. Martínez-Miravé, M. Masip, D. Mattingly, N. Mavromatos, A. Mazumdar, F. Méndez, F. Mercati, S. Micanovic, J. Mielczarek, A.L. Miller, M. Milosevic, D. Minic, L. Miramonti, V.A. Mitsou, P. Moniz, S. Mukherjee, G. Nardini, S. Navas, M. Niechciol, A.B. Nielsen, N.A. Obers, F. Oikonomou, D. Oriti, C.F. Paganini, S. Palomares-Ruiz, R. Pasechnik, V. Pasic, C. Pérez de los Heros, C. Pfeifer, M. Pieroni, T. Piran, A. Platania, S. Rastgoo, J.J. Relancio, M.A. Reyes, A. Ricciardone, M. Risse, M.D. Rodriguez Frias, G. Rosati, D. Rubiera-Garcia, H. Sahlmann, M. Sakellariadou, F. Salamida, E.N. Saridakis, P. Satunin, M. Schiffer, F. Schüssler, G. Sigl, J. Sitarek, J. Solà Peracaula, C.F. Sopuerta, T.P. Sotiriou, M. Spurio, D. Staicova, N. Stergioulas, S. Stoica, J. Strišković, T. Stuttard, D. Sunar Cerci, Y. Tavakoli, C.A. Ternes, T. Terzić, T. Thiemann, P. Tinyakov, M.D.C. Torri, M. Tórtola, C. Trimarelli, T. Trześniewski, A. Tureanu, F.R. Urban, E.C. Vagenas, D. Vernieri, V. Vitagliano, J.-C. Wallet, J.D. Zornoza, Addazi, A., Alvarez-Muniz, J., Alves Batista, R., Amelino-Camelia, G., Antonelli, V., Arzano, M., Asorey, M., Atteia, J. -L., Bahamonde, S., Bajardi, F., Ballesteros, A., Baret, B., Barreiros, D. M., Basilakos, S., Benisty, D., Birnholtz, O., Blanco-Pillado, J. J., Blas, D., Bolmont, J., Boncioli, D., Bosso, P., Calcagni, G., Capozziello, S., Carmona, J. M., Cerci, S., Chernyakova, M., Clesse, S., Coelho, J. A. B., Colak, S. M., Cortes, J. L., Das, S., D'Esposito, V., Demirci, M., Di Luca, M. G., di Matteo, A., Dimitrijevic, D., Djordjevic, G., Prester, D. D., Eichhorn, A., Ellis, J., Escamilla-Rivera, C., Fabiano, G., Franchino-Vinas, S. A., Frassino, A. M., Frattulillo, D., Funk, S., Fuster, A., Gamboa, J., Gent, A., Gergely, L. A., Giammarchi, M., Giesel, K., Glicenstein, J. -F., Gracia-Bondia, J., Gracia-Ruiz, R., Gubitosi, G., Guendelman, E. I., Gutierrez-Sagredo, I., Haegel, L., Heefer, S., Held, A., Herranz, F. J., Hinderer, T., Illana, J. I., Ioannisian, A., Jetzer, P., Joaquim, F. R., Kampert, K. -H., Uysal, A. K., Katori, T., Kazarian, N., Kerszberg, D., Kowalski-Glikman, J., Kuroyanagi, S., Lammerzahl, C., Said, J. L., Liberati, S., Lim, E., Lobo, I. P., Lopez-Moya, M., Luciano, G. G., Manganaro, M., Marciano, A., Martin-Moruno, P., Martinez, M., Martinez-Huerta, H., Martinez-Mirave, P., Masip, M., Mattingly, D., Mavromatos, N., Mazumdar, A., Mendez, F., Mercati, F., Micanovic, S., Mielczarek, J., Miller, A. L., Milosevic, M., Minic, D., Miramonti, L., Mitsou, V. A., Moniz, P., Mukherjee, S., Nardini, G., Navas, S., Niechciol, M., Nielsen, A. B., Obers, N. A., Oikonomou, F., Oriti, D., Paganini, C. F., Palomares-Ruiz, S., Pasechnik, R., Pasic, V., Perez de los Heros, C., Pfeifer, C., Pieroni, M., Piran, T., Platania, A., Rastgoo, S., Relancio, J. J., Reyes, M. A., Ricciardone, A., Risse, M., Frias, M. D. R., Rosati, G., Rubiera-Garcia, D., Sahlmann, H., Sakellariadou, M., Salamida, F., Saridakis, E. N., Satunin, P., Schiffer, M., Schussler, F., Sigl, G., Sitarek, J., Peracaula, J. S., Sopuerta, C. F., Sotiriou, T. P., Spurio, M., Staicova, D., Stergioulas, N., Stoica, S., Striskovic, J., Stuttard, T., Cerci, D. S., Tavakoli, Y., Ternes, C. A., Terzic, T., Thiemann, T., Tinyakov, P., Torri, M. D. C., Tortola, M., Trimarelli, C., Trzesniewski, T., Tureanu, A., Urban, F. R., Vagenas, E. C., Vernieri, D., Vitagliano, V., Wallet, J. -C., Zornoza, J. D., AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), A. Addazi, J. Alvarez-Muniz, R. Alves Batista, G. Amelino-Camelia, V. Antonelli, M. Arzano, M. Asorey, J.-L. Atteia, S. Bahamonde, F. Bajardi, A. Ballestero, B. Baret, D.M. Barreiro, S. Basilako, D. Benisty, O. Birnholtz, J.J. Blanco-Pillado, D. Bla, J. Bolmont, D. Boncioli, P. Bosso, G. Calcagni, S. Capozziello, J.M. Carmona, S. Cerci, M. Chernyakov, S. Clesse, J.A.B. Coelho, S.M. Colak, J.L. Corte, S. Da, V. D???Esposito, M. Demirci, M.G. Di Luca, A. di Matteo, D. Dimitrijevic, G. Djordjevic, D. Dominis Prester, A. Eichhorn, J. Elli, C. Escamilla-Rivera, G. Fabiano, S.A. Franchino-Vi??a, A.M. Frassino, D. Frattulillo, S. Funk, A. Fuster, J. Gamboa, A. Gent, L.??. Gergely, M. Giammarchi, K. Giesel, J.-F. Glicenstein, J. Gracia-Bond??a, R. Gracia-Ruiz, G. Gubitosi, E.I. Guendelman, I. Gutierrez-Sagredo, L. Haegel, S. Heefer, A. Held, F.J. Herranz, T. Hinderer, J.I. Illana, A. Ioannisian, P. Jetzer, F.R. Joaquim, K.-H. Kampert, A. Karasu Uysal, T. Katori, N. Kazarian, D. Kerszberg, J. Kowalski-Glikman, S. Kuroyanagi, C. L??mmerzahl, J. Levi Said, S. Liberati, E. Lim, I.P. Lobo, M. L??pez-Moya, G.G. Luciano, M. Manganaro, A. Marcian??, P. Mart??n-Moruno, Manel Martinez, Mario Martinez, H. Mart??nez-Huerta, P. Mart??nez-Mirav??, M. Masip, D. Mattingly, N. Mavromato, A. Mazumdar, F. M??ndez, F. Mercati, S. Micanovic, J. Mielczarek, A.L. Miller, M. Milosevic, D. Minic, L. Miramonti, V.A. Mitsou, P. Moniz, S. Mukherjee, G. Nardini, S. Nava, M. Niechciol, A.B. Nielsen, N.A. Ober, F. Oikonomou, D. Oriti, C.F. Paganini, S. Palomares-Ruiz, R. Pasechnik, V. Pasic, C. P??rez de los Hero, C. Pfeifer, M. Pieroni, T. Piran, A. Platania, S. Rastgoo, J.J. Relancio, M.A. Reye, A. Ricciardone, M. Risse, M.D. Rodriguez Fria, G. Rosati, D. Rubiera-Garcia, H. Sahlmann, M. Sakellariadou, F. Salamida, E.N. Saridaki, P. Satunin, M. Schiffer, F. Sch??ssler, G. Sigl, J. Sitarek, J. Sol?? Peracaula, C.F. Sopuerta, T.P. Sotiriou, M. Spurio, D. Staicova, N. Stergioula, S. Stoica, J. Stri??kovi??, T. Stuttard, D. Sunar Cerci, Y. Tavakoli, C.A. Terne, T. Terzi??, T. Thiemann, P. Tinyakov, M.D.C. Torri, M. T??rtola, C. Trimarelli, T. Trze??niewski, A. Tureanu, F.R. Urban, E.C. Vagena, D. Vernieri, V. Vitagliano, J.-C. Wallet, J.D. Zornoza, Laboratoire de Physique Théorique d'Orsay [Orsay] (LPT), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Generalitat de Catalunya, European Commission, Xunta de Galicia, Ministerio de Economía y Competitividad (España), European Research Council, Eusko Jaurlaritza, Generalitat Valenciana, Japan Society for the Promotion of Science, and Comunidad de Madrid

Subjects
High Energy Physics - Theory, CAUSAL DYNAMICAL TRIANGULATIONS, Ultra-high-energy cosmic rays, [PHYS.MPHY]Physics [physics]/Mathematical Physics [math-ph], Lorentz invariance violation and deformation, Gamma-ray astronomy, Cosmic neutrinos, Gravitational waves, General Relativity and Quantum Cosmology, Lorentz transformations, Gravitational waves -- Detection, High Energy Physics - Phenomenology (hep-ph), Astronomi, astrofysik och kosmologi, Gamma ray astronomy, Astronomy, Astrophysics and Cosmology, Cosmic neutrino, astro-ph.HE, High Energy Astrophysical Phenomena (astro-ph.HE), General Relativity and Cosmology, hep-th, hep-ph, Quantum cosmology, ENERGY COSMIC-RAYS, High Energy Physics - Phenomenology, [PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc], Neutrinos -- Scattering, Astrophysics - High Energy Astrophysical Phenomena, Particle Physics - Theory, Gravitational wave, ACTIVE GALACTIC NUCLEI, Astrophysics and Astronomy, Nuclear and High Energy Physics, [PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE], gr-qc, FOS: Physical sciences, General Relativity and Quantum Cosmology (gr-qc), GAMMA-RAY BURST, DOUBLY-SPECIAL RELATIVITY, Ultra-high-energy cosmic ray, Particle Physics - Phenomenology, PRIMORDIAL BLACK-HOLES, Matematikk og Naturvitenskap: 400::Fysikk: 430 [VDP], COHERENT STATES GCS, Quantum gravity, GENERALIZED UNCERTAINTY PRINCIPLE, EXTRAGALACTIC BACKGROUND LIGHT, High Energy Physics - Theory (hep-th), [PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph], LORENTZ INVARIANCE VIOLATION
Abstract

The exploration of the universe has recently entered a new era thanks to the multimessenger paradigm, characterized by a continuous increase in the quantity and quality of experimental data that is obtained by the detection of the various cosmic messengers (photons, neutrinos, cosmic rays and gravitational waves) from numerous origins. They give us information about their sources in the universe and the properties of the intergalactic medium. Moreover, multi-messenger astronomy opens up the possibility to search for phenomenological signatures of quantum gravity. On the one hand, the most energetic events allow us to test our physical theories at energy regimes which are not directly accessible in accelerators; on the other hand, tiny effects in the propagation of very high energy particles could be amplified by cosmological distances. After decades of merely theoretical investigations, the possibility of obtaining phenomenological indications of Planck-scale effects is a revolutionary step in the quest for a quantum theory of gravity, but it requires cooperation between different communities of physicists (both theoretical and experimental). This review, prepared within the COST Action CA18108 ‘‘Quantum gravity phenomenology in the multi-messenger approach", is aimed at promoting this cooperation by giving a state-of-the art account of the interdisciplinary expertise that is needed in the effective search of quantum gravity footprints in the production, propagation and detection of cosmic messengers., Talent Scientific Research Program of College of Physics, Sichuan University 1082204112427, Fostering Program in Disciplines Possessing Novel Features for Natural Science of Sichuan University 2020SCUNL209, 1000 Talent program of Sichuan province 2021, Xunta de Galicia, European Commission European Union ERDF, "Maria de Maeztu'' Units of Excellence program MDM-2016-0692, Red Tematica Nacional de Astroparticulas RED2018-102661-T, La Caixa Foundation 100010434, European Commission 847648 LCF/BQ/PI21/11830030 754510, Ministry of Education, Science & Technological Development, Serbia 451-03-9/2021-14/200124, FSR Incoming Postdoctoral Fellowship Ministry of Education, Science and Technological Development, Serbia 451-03-9/2021-14/200124, University of Rijeka grant uniri-prirod-18-48, Croatian Science Foundation (HRZZ) IP-2016-06-9782, Villum Fonden 29405 DGA-FSE 2020-E2117R, European Regional Development Fund through the Center of Excellence (TK133) "The Dark Side of the Universe'' European Regional Development Fund (ESIF/ERDF), Ministry of Education, Youth & Sports - Czech Republic CoGraDS-CZ.02.1.01/0.0/0.0/15 003/0000437, Blavatnik grant, Basque Government IT-97916 Basque Foundation for Science (IKERBASQUE), European Space Agency C4000120711 4000132310, FNRS (Belgian Fund for Research), Programa de Apoyo a Proyectos de Investigacion e Innovacion Tecnologica (PAPIIT), Universidad Nacional Autonoma de Mexico TA100122, National University of La Plata X909 DICYT 042131GR, National Research, Development & Innovation Office (NRDIO) - Hungary 123996, FQXi, Swiss National Science Foundation (SNSF), European Commission 181461 199307, Netherlands Organization for Scientific Research (NWO) 680-91-119 15MV71, Ministry of Education, Culture, Sports, Science and Technology, Japan (MEXT) Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research (KAKENHI) 20H01899 20H05853 JP21F21789, Estonian Research Council PRG356, Julian Schwinger Foundation, Generalitat Valenciana Excellence PROMETEO-II/2017/033 PROMETEO/2018/165, Istituto Nazionale di Fisica Nucleare (INFN), European ITN project HIDDeN H2020-MSCA-ITN-2019//860881-HIDDeN, Swedish Research Council, European Commission 2016-05996 European Research Council (ERC) European Commission 668679, Advanced ERC grant TReX, Ministry of Education, Universities and Research (MIUR) 2017X7X85K, Fonds de la Recherche Scientifique - FNRS 4.4501.18, Ministry of Research, Innovation and Digitization - Romania PN19-030102-INCDFM PN-III-P4ID-PCE-2020-2374, United States Department of Energy (DOE) DE-SC0020262, Ministry of Science, ICT & Future Planning, Republic of Korea 075-15-2020-778, German Academic Scholarship Foundation German Research Foundation (DFG) 408049454 420243324 425333893 445990517 Germany's Excellence Strategy (EXC 2121 "Quantum Universe'') 390833306 390837967 Federal Ministry of Education & Research (BMBF) 05 A20GU2 05 A20PX1, Centro de Excelencia "Severo Ochoa'' SEV-2016-0588, CERCA program of the Generalitat de Catalunya, Agencia de Gestio D'Ajuts Universitaris de Recerca Agaur (AGAUR) Generalitat de Catalunya 2017-SGR-1469 2017-SGR-929 ICCUB CEX2019-000918-M, National Science Centre, Poland 2019/33/B/ST2/00050 2017/27/B/ST2/01902, Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ) 306414/2020-1, Dicyt-USACH 041931MF, National Science Fund of Bulgaria KP-06-N 38/11 RCN ROMFORSK 302640, Comunidad de Madrid 2018-T1/TIC-10431 2019-T1/TIC-13177 S2018/NMT-4291, UK Research & Innovation (UKRI), Science & Technology Facilities Council (STFC) ST/T000759/1 ST/P000258/1 ST/T000732/1 ST/V005596/1, Portuguese Foundation for Science and Technology UIDB/00618/2020 UIDB/00777/2020 UIDP/00777/2020 CERN/FIS-PAR/0004/2019 PTDC/FIS-PAR/29436/2017 PTDC/FISPAR/31938/2017 PTDC/FIS-OUT/29048/2017 SFRH/BD/137127/2018, Centre National de la Recherche Scientifique (CNRS), LabEx UnivEarthS ANR-10-LABX-0023 ANR18-IDEX-0001, Junta de Andalucia European Commission A-FQM-053-UGR18, Natural Sciences and Engineering Research Council of Canada (NSERC) RGPIN-2021-03644, National Science Centre Poland Sonata Bis 2019/33/B/ST2/00050 DEC-2017/26/E/ST2/00763, Natural Sciences and Engineering Research Council of Canada (NSERC) DGIID-DGA 2015-E24/2, Spanish Research State Agency and Ministerio de Ciencia e Innovacion MCIN/AEI PID2019-104114RB-C32 PID2019-105544GB-I00 PID2019-105614GB-C21 PID2019106515GB-I00 PID2019-106802GB-I00 PID2019-107394GB-I00 PID2019-107844GB-C21 PID2019-107847RB-C41 MCIN/AEI PGC2018-095328-B-I00 PGC2018-094856-B-I00 PGC2018-096663-B-C41 PGC2018-096663-B-C44 PGC2018-094626-BC21 PGC2018-101858-B-I00 FPA2017-84543-P FPA2016-76005-C2-1-P, Spanish 'Ministerio de Universidades' BG20/00228 Spanish Government PID2020-115845GBI00 Generalitat de Catalunya Comunidad de Madrid S2018/NMT-4291 Spanish Government PID2019-105544GB-I00, Perimeter Institute for Theoretical Physics, Government of Canada through the Department of Innovation, Science and Economic Development, Province of Ontario through the Ministry of Colleges and Universities, Centre National de la Recherche Scientifique (CNRS), Netherlands Organization for Scientific Research (NWO), Fundamental Questions Institute (FQXi), European Cooperation in Science and Technology (COST) CA18108, Research Council of University of Guilan, Iniziativa Specifica TEONGRAV Iniziativa Specifica QGSKY Iniziativa Specifica QUAGRAP Iniziativa Specifica GeoSymQFT, the Spanish Research State Agency and Ministerio de Ciencia e Innovacion MCIN/AEI PID2020-115845GBI00 PID2019-108485GB-I00 PID2020-113334GB-I00 PID2020-113701GB-I00 PID2020-113775GB-I00 PID2020-118159GB-C41 PID2020-118159GA-C42 PRE2019-089024, Rothchild grant UID/MAT/00212/2020 FPU18/04571

Published
2022
Full Text
View/download PDF

24. DIAGNÓSTICO BIOCLIMÁTICO PARA PRODUÇÃO DE MELÃO NO MUNICÍPIO DE PATOS – PB

Author

R. S. Silva, D. A. Furtado, L. M. S. Xavier, N. M. H. Mascarenhas, M. G. D. Silva, V. S. Rodrigues, and A. R. F. Batista

Abstract

A condições ambientais que possibilitam o cultivo do meloeiro estão relacionadas, sobretudo, aos fatores climáticos, tais como temperatura, luminosidade, umidade relativa do ar e características do solo e, a junção dessas condições pode favorecer ao meloeiro aumentar a produtividade de frutos e qualidade comercial. A pesquisa teve como objetivo avaliar as condições climatológicas e verificar a viabilidade da produção de melão cantaloupe no município de Patos, região semiárida paraibana. Os dados meteorológicos utilizados foram obtidos no Instituto Nacional de Meteorologia (INMET), no período de 2000 a 2020, sendo os elementos meteorológicos avaliados às temperaturas máximas, médias e mínimas e umidade relativa do ar, confrontando-se os dados obtidos com os dados ideais para a produção do melão. instalações para seu cultivo. Constatou-se que no município de Patos apresenta durante o ano temperaturas máximas acima das exigidas pelo melão em todas as fases produtivas, sendo que temperaturas acima de 35 °C, como ocorre nos meses de outubro a janeiro.

Published
2022
Full Text
View/download PDF

25. Dietetic management in gastrointestinal complications from antimalignant chemotherapy Dietoterapia en complicaciones gastrointestinales de quimioterápicos

Author

L. Calixto-Lima, E. Martins de Andrade, A. P. Gomes, M. Geller, and R. Siqueira-Batista

Subjects
Quimioterapia, Toxicidad, Dietoterapia, Oncología, Chemoteraphy, Toxicity, Dietetics, Oncology, Nutritional diseases. Deficiency diseases, RC620-627
Abstract

Antineoplastic chemotherapy (CT) represents the systemic treatment of malignant tumors. It can be used alone or combined with surgery and / or radiotherapy. The cytotoxic agents used in chemotherapy work on both cancerous cells and noncancerous cells of the body, generally resulting in high toxicity. The biological aggressiveness of chemotherapy particularly affects rapidly replicating cells, such as those of the digestive tract, resulting in adverse effects that impair food intake, leading to compromised nutritional status and which may lead to cachexia. The main toxic effects of chemotherapy in the gastrointestinal tract include nausea, vomiting -these are the most frequent- constipation, diarrhea, xerostomia, mucositis, dysphagia and anorexia. Given the high frequency of such effects, nutritional intervention should be an integral part of cancer treatment, to maintain and/or improve the patient´s nutritional status and reduce or minimize the side effects caused by treatment. Accordingly, the goal of this study is to review dietetic conduct in the process of caring for patients undergoing cancer chemotherapy.La quimioterapia (QT) representa el tratamiento antineoplásico sistémico de los tumores malignos. Puede ser utilizada solo o combinada con la cirugía y / o radioterapia. Los agentes quimioterápicos actúan en las células cancerosas y las células normales del cuerpo, siendo por lo general muy tóxicos. La agresividad de la quimioterapia afecta especialmente rápida replicación celular en el tracto digestivo, dando lugar a efectos adversos que impiden la ingesta de alimentos, dando lugar al estado nutricional comprometido y puede conducir a la caquexia. Los principales efectos tóxicos de la quimioterapia, el tracto gastrointestinal, como náuseas, vómitos estos son los más frecuentes- estreñimiento, diarrea, sequedad de boca, mucositis disfagia y anorexia. Dada la alta frecuencia de tales efectos, la intervención nutricional debe ser parte integral del tratamiento del cáncer, para mantener y/o mejorar el estado nutricional del paciente y reducir o minimizar los efectos secundarios del tratamiento. En efecto, la revisión de la dietética conducta en el proceso de cuidar de los pacientes en quimioterapia contra el cáncer es el objetivo de este trabajo.

Published
2012

26. CITOTOXICIDADE DO EXTRATO BRUTO DE Bacillus amyloliquefaciens FRENTE A HEMÃCIAS DE CARNEIRO E CÉLULAS VERO

Author

D. SCHULZ, C. M. O. SIMÕES, C. R. A. FRÖHNER, N. H. GABILAN, and C. R. V. BATISTA

Subjects
Bacillus amyloliquefaciens, antimicrobianos, citotoxicidade., Nutrition. Foods and food supply, TX341-641
Abstract

Avaliou-se a citotoxicidade do extrato bruto de Bacillus amyloliquefaciens contra hemácias de carneiro e células Vero. O extrato bruto de Bacillus amyloliquefaciens foi obtido por técnicas de precipitação, centrifugação, diálise e esterilização por filtração. O extrato bruto apresentou uma concentração hemolítica 50% em tubos na concentração de 11,43 g de proteína numa suspensão de eritrócitos de carneiro e uma concentração citotóxica 50% na concentração de 32,14 g de proteína em células Vero. Os resultados obtidos indicam que o extrato bruto de Bacillus amyloliquefaciens apresentou efeito citotóxico tanto contra hemácias de carneiro como em células Vero.

Published
2009

28. Cherenkov Telescope Array : the World’s largest VHE gamma-ray observatory

Author

Roberta Zanin, H. Abdalla, H. Abe, S. Abe, A. Abusleme, F. Acero, A. Acharyya, V. Acin Portella, K. Ackley, R. Adam, C. Adams, S.S. Adhikari, I. Aguado Ruesga, I. Agudo, R. Aguilera, A. Aguirre Santaella, F. Aharonian, A. Alberdi, R. Alfaro, J. Alfaro, C. Alispach, R. Aloisio, R. Alves Batista, J.P. Amans, L. Amati, E. Amato, L. Ambrogi, G. Ambrosi, M. Ambrosio, R. Ammendola, J. Anderson, M. Anduze, E.O. Anguner, L.A. Antonelli, V. Antonuccio, P. Antoranz, R. Anutarawiramkul, J. Aragunde Gutierrez, C. Aramo, A. Araudo, M. Araya, A. Arbet Engels, C. Arcaro, V. Arendt, C. Armand, T. Armstrong, F. Arqueros, L. Arrabito, B. Arsioli, M. Artero, K. Asano, Y. Ascasibar, J. Aschersleben, M. Ashley, P. Attina, P. Aubert, C. B. Singh, D. Baack, A. Babic, M. Backes, V. Baena, S. Bajtlik, A. Baktash, C. Balazs, M. Balbo, O. Ballester, J. Ballet, B. Balmaverde, A. Bamba, R. Bandiera, A. Baquero Larriva, P. Barai, C. Barbier, V. Barbosa Martins, M. Barcelo, M. Barkov, M. Barnard, L. Baroncelli, U. Barres de Almeida, J.A. Barrio, D. Bastieri, P.I. Batista, I. Batkovic, C. Bauer, R. Bautista González, J. Baxter, U. Becciani, J. Becerra González, Y. Becherini, G. Beck, J. Becker Tjus, W. Bednarek, A. Belfiore, L. Bellizzi, R. Belmont, W. Benbow, D. Berge, E. Bernardini, M.I. Bernardos, K. Bernlöhr, A. Berti, M. Berton, B. Bertucci, V. Beshley, N. Bhatt, S. Bhattacharyya, W. Bhattacharyya, B. Y. Bi, G. Bicknell, N. Biederbeck, C. Bigongiari, A. Biland, R. Bird, E. Bissaldi, J. Biteau, M. Bitossi, O. Blanch, M. Blank, J. Blazek, J. Bobin, C. Boccato, F. Bocchino, C. Boehm, M. Bohacova, C. Boisson, J. Boix, J.P. Bolle, J. Bolmont, G. Bonanno, C. Bonavolontà, L. Bonneau Arbeletche, G. Bonnoli, P. Bordas, J. Borkowski, R. Bose, D. Bose, Z. Bosnjak, E. Bottacini, Markus Böttcher, M.T. Botticella, C. Boutonnet, F. Bouyjou, V. Bozhilov, E. Bozzo, L. Brahimi, C. Braiding, S. Brau Nogue, S. Breen, J. Bregeon, M. Breuhaus, A. Brill, W. Brisken, E. Brocato, A.M. Brown, K. Brügge, P. Brun, F. Brun, L. Brunetti, G. Brunetti, P. Bruno, A. Bruno, A. Bruzzese, N. Bucciantini, J. H. Buckley, R. Bühler, A. Bulgarelli, T. Bulik, M. Bünning, M. Bunse, M. Burton, A. Burtovoi, M. Buscemi, S. Buschjager, G. Busetto, J. Buss, K. Byrum, A. Caccianiga, F. Cadoux, A. Calanducci, C. Calderon, J. Calvo Tovar, R. A. Cameron, P. Campana, R. Canestrari, F. Cangemi, B. Cantlay, M. Capalbi, M. Capasso, M. Cappi, A. Caproni, R. Capuzzo Dolcetta, P. Caraveo, V. Cárdenas, L. Cardiel, M. Cardillo, C. Carlile, S. Caroff, R. Carosi, A. Carosi, E. Carquin, M. Carrere, J.M. Casandjian, S. Casanova, F. Cassol, F. Catalani, O. Catalano, D. Cauz, A. Ceccanti, C. Celestino Silva, K. Cerny, M. Cerruti, E. Chabanne, P. Chadwick, Y. Chai, P. Chambery, C. Champion, S. Chaty, A. Chen, K. Cheng, M. Chernyakova, G. Chiaro, A. Chiavassa, M. Chikawa, V.R. Chitnis, J. Chudoba, L. Chytka, S. Cikota, A. Circiello, P. Clark, M. Colak, E. Colombo, S. Colonges, A. Comastri, A. Compagnino, V. Conforti, E. Congiu, R. Coniglione, J. Conrad, F. Conte, J.L. Contreras, P. Coppi, R. Cornat, J. Coronado Blazquez, J. Cortina, A. Costa, H. Costantini, G. Cotter, B. Courty, S. Covino, S. Crestan, P. Cristofari, R. Crocker, J. Croston, K. Cubuk, O. Cuevas, X. Cui, G. Cusumano, S. Cutini, G. D'Amico, F. D'Ammando, P. D'Avanzo, P. Da Vela, M. Dadina, S. Dai, M. Dalchenko, M. Dall'Ora, M.K. Daniel, J. Dauguet, I. Davids, J. Davies, B. Dawson, A. De Angelis, A.E. de Araujo Carvalho, M. de Bony de Lavergne, G. De Cesare, F. de Frondat, I. de la Calle, E. de Gouveia Dal Pino, B. De Lotto, A. De Luca, D. De Martino, M. de Naurois, E. de Ona Wilhelmi, F. De Palma Persio, N. De Simone, V. de Souza Valle, E. Delagnes, G. Deleglise Reznicek, C. Delgado, A.G. Delgado Giler, J. Delgado Mengual Valle, Domenico Della Volpe, D. Depaoli, J. Devin, T. Di Girolamo, C. Di Giulio Pierro, L. Di Venere, C. Díaz, C. Dib, S. Diebold, S. Digel, A. Djannati Atai, J. Djuvsland, A. Dmytriiev, K. Docher, A. Domínguez, D. Dominis Prester, A. Donini, D. Dorner, M. Doro, Rita Cassia dos Anjos, J.L. Dournaux, T. Downes, G. Drake, H. Drass, D. Dravins, C. Duangchan, A. Duara, G. Dubus, L. Ducci, C. Duffy, D. Dumora, K. Dundas Mora, A. Durkalec, V.V. Dwarkadas, J. Ebr, C. Eckner, J. Eder, E. Edy, K. Egberts, S. Einecke, C. Eleftheriadis, D. Elsässer, G. Emery, D. Emmanoulopoulos, J.P. Ernenwein, M. Errando, P. Escarate, J. Escudero, C. Espinoza, S. Ettori, A. Eungwanichayapant, P. Evans, C. Evoli, M. Fairbairn, D. Falceta Goncalves, A. Falcone, V. Fallah Ramazanı, R. Falomo, K. Farakos, G. Fasola, A. Fattorini, Y. Favre, R. Fedora, E. Fedorova, K. Feijen, Q. Feng, G. Ferrand, G. Ferrara, O. Ferreira, M. Fesquet, E. Fiandrini, A. Fiasson, M. Filipovic, D. Fink, J.P. Finley, V. Fioretti, D.F.G. Fiorillo, M. Fiorini, S. Flis, H. Flores, L. Foffano, C. Fohr, M.V. Fonseca, L. Font, G. Fontaine, O. Fornieri, P. Fortin, L. Fortson, N. Fouque, B. Fraga, A. Franceschini, F.J. Franco, L. Freixas Coromina, L. Fresnillo, D. Fugazza, Y. Fujita, S. Fukami, Y. Fukazawa, D. Fulla, S. Funk, A. Furniss, S. Gabici, D. Gaggero, G. Galanti, P. Galdemard, Y. A. Gallant, D. Galloway, S. Gallozzi, V. Gammaldi, R. Garcia, L. E. García-Muñoz, E. Garcia Lopez, F. Gargano, C. Gargano, S. Garozzo, D. Gascon, T. Gasparetto, D. Gasparrini, H. Gasparyan, M. Gaug, N. Geffroy, A. Gent, S. Germani, A. Ghalumyan, A. Ghedina, G. Ghirlanda, F. Gianotti, S. Giarrusso, M. Giarrusso, G. Giavitto, B. Giebels, N. Giglietto, V. Gika, F. Gillardo, R. Gimenes, F. Giordano, E. Giro, M. Giroletti, Andrea Giuliani, M. Gjaja, J.F. Glicenstein, P. Gliwny, H. Goksu, P. Goldoni, J.L. Gomez, M.M. Gonzalez, Juan Manuel Gonzalez, K.S. Gothe, D. Gotz Coelho, T. Grabarczyk, R. Graciani, P. Grandi, G. Grasseau, D. Grasso, D. Green, J. Green, T. Greenshaw, P. Grespan, A. Grillo, M.H. Grondin, J. Grube, V. Guarino, B. Guest, O. Gueta, M. Günduz, S. Gunji, G. Gyuk, J. Hackfeld, D. Hadasch, L. Hagge, A. Hahn, J.E. Hajlaoui, A. Halim, P. Hamal, W. Hanlon, Y. Harada, M.J. Hardcastle, M. Harvey Collado, T. Haubold, A. Haupt, M. Havelka, K. Hayashi, M. Hayashida, H. He, L. Heckmann, M. Heller, F. Henault, Gilles Henri, G. Hermann, S. Hernández Cadena, J. Herrera Llorente, O. Hervet, J. Hinton, A. Hiramatsu, K. Hirotani, B. Hnatyk, R. Hnatyk, J.K. Hoang, D. H.H. Hoffmann, C. Hoischen, J. Holder, M. Holler, B. Hona, D. Horan, Dieter Horns, P. Horvath, J. Houles, M. Hrabovsky, D. Hrupec, Y. Huang, J.‑M. Huet, G. Hughes, G. Hull, T.B. Humensky, M. Hütten, M. Iarlori, J.M. Illa, R. Imazawa, T. Inada, F. Incardona, A. Ingallinera, S. Inoue, T. Inoue, Y. Inoue, F. Iocco, K. Ioka, M. Ionica, S. Iovenitti, A. Iriarte, K. Ishio, W. Ishizaki, Y. Iwamura, J. Jacquemier, M. Jacquemont, M. Jamrozy, P. Janecek, F. Jankowsky, A. JardinBlicq, C. Jarnot, P. Jean Martínez, L. Jocou, N. Jordana, M. Josselin, I. JungRichardt, F.J.P.A. Junqueira, C. Juramy Gilles, P. Kaaret, L.H.S. Kadowaki, M. Kagaya, R. Kankanyan, D. Kantzas, V. Karas, A. Karastergiou, S. Karkar, J. Kasperek, H. Katagiri, J. Kataoka, K. Katarzynski, S. Katsuda, N. Kawanaka, D. Kazanas, D. Kerszberg, B. Khélifi, M.C. Kherlakian, T.P. Kian, D.B. Kieda, T. Kihm, S. Kim, S. Kisaka, R. Kissmann, R. Kleijwegt, G. Kluge, W. Kluźniak, J. Knapp, A. Kobakhidze, Y. Kobayashi, B. Koch, J. Kocot, K. Kohri, N. Komin, A. Kong, K. Kosack, F. Krack, M. Krause, F. Krennrich, H. Kubo, V. N. Kudryavtsev, S. Kunwar, J. Kushida, P. Kushwaha, Barbera Parola, G. La Rosa, R. Lahmann, A. Lamastra, M. Landoni, D. Landriu, R.G. Lang, J. Lapington, P. Laporte, P. Lason, J. Lasuik, J. Lazendic Galloway, T. Le Flour, P. Le Sidaner, S. Leach, S.H. Lee, W.H. Lee, S. Lee Oliveira, A. Lemiere, M. Lemoine Goumard, J.P. Lenain, F. Leone, V. Leray, G. Leto, F. Leuschner, R. Lindemann, E. Lindfors, L. Linhoff, I. Liodakis, A. Lipniacka, M. Lobo, Thomas Lohse, S. Lombardi, A. Lopez, M. Lopez, R. Lopez Coto, F. Louis, M. Louys, F. Lucarelli, H. Ludwig Boudi, P.L. Luque Escamilla, M.C. Maccarone, E. Mach, A.J. Maciejewski, J. Mackey, P. Maeght, C. Maggio, G. Maier, P. Majumdar, M. Makariev, M. Mallamaci, R. Malta Nunes de Almeida, D. Malyshev, D. Mandat, G. Maneva, M. Manganaro, P. Manigot, K. Mannheim, N. Maragos, D. Marano, M. Marconi, A. Marcowith, M. Marculewicz, B. Marcun, J. Marin, N. Marinello, P. Marinos, S. Markoff, P. Marquez, G. Marsella, J. M. Martin, P. G. Martin, M. Martinez, G. Martinez, O. Martinez, H. Martinez Huerta, C. Marty, R. Marx, N. Masetti, P. Massimino, H. Matsumoto, N. Matthews, G. Maurin, W. Max Moerbeck, N. Maxted, M.N. Mazziotta, S.M. Mazzola, J.D. Mbarubucyeye, L. Mc Comb, I. McHardy, S. McKeague, S. McMuldroch, E. Medina, D. Medina Miranda, A. Melandri, C. Melioli, D. Melkumyan, S. Menchiari, S. Mereghetti, G. Merino Arevalo, E. Mestre, J.L. Meunier, T. Meures, S. Micanovic, M. Miceli, M. Michailidis, J. Michalowski, T. Miener, I. Mievre, J. D. Miller, T. Mineo, M. Minev, J.M. Miranda, A. Mitchell, T. Mizuno, B. A. Mode, R. Moderski, L. Mohrmann, E. Molinari, T. Montaruli, I. Monteiro, C. Moore, A. Moralejo, D. Morcuende Parrilla, E. Moretti, K. Mori, P. Moriarty, K. Morik, P. Morris, A. Morselli, K. Mosshammer, R. Mukherjee, J. Muller, C. Mundell, J. Mundet, T. Murach, A. Muraczewski, H. Muraishi, I. Musella, A. Musumarra, A. Nagai, S. Nagataki, T. Naito, T. Nakamori, K. Nakashima, K. Nakayama, N. Nakhjiri, G. Naletto, D. Naumann, L. Nava, M.A. Nawaz, H. Ndiyavala, D. Neise, L. Nellen, R. Nemmen, N. Neyroud, K. Ngernphat, T. Nguyen Trung, L. Nicastro, L. Nickel, J. Niemiec, D. Nieto, C. Nigro, M. Nikołajuk, D. Ninci, K. Noda, Y. Nogami, S. Nolan, R. P. Norris, D. Nosek, M. Nöthe, V. Novotny, S. Nozaki, F. Nunio, P. O'Brien, K. Obara, Y. Ohira, M. Ohishi, S. Ohm, T. Oka, N. Okazaki, A. Okumura, C. Oliver, G. Olivera, B. Olmi, M. Orienti, R. Orito, M. Orlandini, E. Orlando, J.P. Osborne, M. Ostrowski, N. Otte, E. Ovcharov, E. Owen, I. Oya, A. Ozieblo, M. Padovani, A. Pagliaro, A. Paizis, M. Palatiello, M. Palatka, E. Palazzi, J.‑L. Panazol, D. Paneque, S. Panny, Francesca Romana Pantaleo, M. Panter, M. Paolillo, A. Papitto, A. Paravac, J.M. Paredes, G. Pareschi, N. Parmiggiani, R.D. Parsons, P. Paśko, S. R. Patel, B. Patricelli, L. Pavletic, S. Pavy, A. Peer, M. Pecimotika, M.G. Pellegriti, P. Peñil Del Campo, A. Pepato, S. Perard, C. Perennes, M. Peresano, A. Perez Aguilera, J. Perez Romero, M.A. Perez Torres, M. Persic, P. O. Petrucci, O. Petruk, B. Peyaud, K. Pfrang, E. Pian, P. Piatteli, E. Pietropaolo, R. Pillera, D. Pimentel, F. Pintore, C. Pio Garcia, G. Pirola, F. Piron, S. Pita, M. Pohl, V. Poireau, A. Pollo, M. Polo, C. Pongkitivanichkul, J. Porthault, J. Powell, D. Pozo, R.R. Prado, E. Prandini, J. Prast, K. Pressard, G. Principe, N. Produit, D. Prokhorov, H. Prokoph, H. Przybilski, E. Pueschel, G. Pühlhofer, I. Puljak, M.L. Pumo, M. Punch, F. Queiroz, J. Quinn, A. Quirrenbach, P.J. Rajda, R. Rando, S. Razzaque, S. Recchia, P. Reichherzer, O. Reimer, A. Reisenegger, Q. Remy, M. Renaud, T. Reposeur, B. Reville, J.M. Reymond, J. Reynolds, D. Ribeiro, M. Ribo, G. Richards, J. Rico, F. Rieger, L. Riitano, M. Riquelme, D. Riquelme, S. Rivoire, V. Rizi, E. Roache, M. Roche, J. Rodriguez, G. Rodriguez Fernandez, J.C. Rodriguez Ramirez, J.J. Rodriguez Vazquez, G. Rojas, P. Romano, G. Romeo Lobato, C. Romoli, M. Roncadelli, J. Rosado, A. Rosales de Leon, G. Rowell, A. Rugliancich, J.E. Ruiz del Mazo, C. Rulten, C. Russell, F. Russo Hatlen, S. Safi Harb, L. Saha, V. Sahakian, S. Sailer, T. Saito, N. Sakaki, S. Sakurai, G. Salina, H. Salzmann, D. Sanchez, H. Sandaker, A. Sandoval, P. Sangiorgi, M. Sanguillon, H. Sano, M. Santander, A. Santangelo, R. Santos Lima, A. Sanuy, L. Sapozhnikov, T. Saric, S. Sarkar, H. Sasaki, N. Sasaki, Y. Sato, F.G. Saturni, M. Sawada, J. Schaefer, A. Scherer, J. Scherpenberg, P. Schipani, B. Schleicher, J. Schmoll, M. Schneider, H. Schoorlemmer, P. Schovanek, F. Schussler, B. Schwab, U. Schwanke, J. Schwarz, E. Sciacca, S. Scuderi, M. Seglar Arroyo, I. Seitenzahl, D. Semikoz, O. Sergijenko, J.E. Serna Franco, Karol Seweryn, V. Sguera, A. Shalchi, R.Y. Shang, P. Sharma, L. Sidoli, J. Sieiro, H. Siejkowski, A. Sillanpaa, B.B. Singh, K.K. Singh, A. Sinha, C. Siqueira, J. Sitarek, P. Sizun, V. Sliusar, D. Sobczynska, R.W. Sobrinho, H. Sol, G. Sottile, H. Spackman, S. Spencer, G. Spengler, D. Spiga, W. Springer, A. Stamerra, S. Stanic, R. Starling, Ł. Stawarz, Stanislav Stefanik, C. Stegmann, A. Steiner, S. Steinmassl, C. Stella, R. Sternberger, M. Sterzel, C. Stevens, B. Stevenson, T. Stolarczyk, G. Stratta, U. Straumann, J. Striskovic, M. Strzys, R. Stuik, M. Suchenek, Y. Sunada, Tiina Suomijarvi, T. Suric, H. Suzuki, P. Swierk, T. Szepieniec, K. Tachihara, G. Tagliaferri, H. Tajima, N. Tajima, D. Tak, H. Takahashi, M. Takahashi, J. Takata, R. Takeishi, T. Tam, M. Tanaka, T. Tanaka, S. Tanaka, M. Tavani, F. Tavecchio, T. Tavernier, A. Russ Taylor, L.A. Tejedor, P. Temnikov, K. Terauchi, J.C. Terrazas, R. Terrier, T. Terzic, M. Teshima, D. Thibaut, F. Thocquenne, W. Tian, L. Tibaldo, A. Tiengo, M. Tluczykont, C.J. Todero Peixoto, K. Toma, L. Tomankova, J. Tomastik, M. Tornikoski, D.F. Torres, E. Torresi, G. Tosti, L. Tosti, N. Tothill, F. Toussenel, G. Tovmassian, C. Trichard, M. Trifoglio, A. Trois, S. Truzzi, A. Tsiahina, B. Turk, A. Tutone, Y. Uchiyama, P. Utayarat, L. Vaclavek, M. Vacula, V. Vagelli, F. Vagnetti, J.A. Valdivia, M. Valentino, A. Valio, B. Vallage, P. Vallania Quispe, A.M. van den Berg, W. van Driel, C. van Eldik, C. van Rensburg, Brian van Soelen, J. Vandenbroucke, G. Vasileiadis, V. Vassiliev, M. Vazquez Acosta, M. Vecchi, A. Vega, J. Veh, P. Veitch, C. Venter, S. Ventura, S. Vercellone, V. Verguilov, G. Verna, S. Vernetto, V. Verzi, G.P. Vettolani, C. Veyssiere, I. Viale, A. Viana, N. Viaux, J. Vignatti, C.F. Vigorito, J. Villanueva, V. Vitale, V. Vittorini, V. Vodeb, N. Vogel, V. Voisin, S. Vorobiov, M. Vrastil, T. Vuillaume, S.J. Wagner, P. Wagner, K. Wakazono, S.P. Wakely, M. Ward, D. Warren, J. Watson, M. Wechakama, P. Wegner, A. Weinstein, C. Weniger, F. Werner, H. Wetteskind, M. L. White, A. Wierzcholska, S. Wiesand, R. Wijers, M. Wilkinson, M. Will, J. Williams, T. J. Williamson, A. Wolter, Y.W. Wong, M. Wood, T. Yamamoto, H. Yamamoto, Y. Yamane, R. Yamazaki, S. Yanagita, L. Yang, S. Yoo, T. Yoshida, T. Yoshikoshi, P. Yu, A. Yusafzai, Michael Zacharias, B. Zaldivar, L. Zampieri, R. Zanin, R. Zanmar Sanchez, D. Zaric, M. Zavrtanik, D. Zavrtanik, Andrzej Zdziarski, A. Zech, H. Zechlin, A. Zenin, A. Zerwekh, K. Ziętara, A. Zink, J. Ziolkowski, M. Zivec, A. Zmija, Współautorami artykułu są członkowie CTA Observatory, CTA Consortium i LST Collaboration w liczbie 1139, Astronomy, Research unit Nuclear & Hadron Physics, and Research unit Astroparticle Physics

Subjects
Physics, Observatory, Gamma ray, Astronomy
Abstract

Very-high Energy (VHE) gamma-ray astroparticle physics is a relatively young field, and observations over the past decade have surprisingly revealed almost two hundred VHE emitters which appear to act as cosmic particle accelerators. These sources are an important component of the Universe, influencing the evolution of stars and galaxies. At the same time, they also act as a probe of physics in the most extreme environments known - such as in supernova explosions, and around or after the merging of black holes and neutron stars. However, the existing experiments have provided exciting glimpses, but often falling short of supplying the full answer. A deeper understanding of the TeV sky requires a significant improvement in sensitivity at TeV energies, a wider energy coverage from tens of GeV to hundreds of TeV and a much better angular and energy resolution with respect to the currently running facilities. The next generation gamma-ray observatory, the Cherenkov Telescope Array Observatory (CTAO), is the answer to this need. In this talk I will present this upcoming observatory from its design to the construction, and its potential science exploitation. CTAO will allow the entire astronomical community to explore a new discovery space that will likely lead to paradigm-changing breakthroughs. In particular, CTA has an unprecedented sensitivity to short (sub-minute) timescale phenomena, placing it as a key instrument in the future of multi-messenger and multi-wavelength time domain astronomy. I will conclude the talk presenting the first scientific results obtained by the LST-1, the prototype of one CTAO telescope type - the Large-Sized Telescope, that is currently under commission., PoS: Proceedings of Science, 395, ISSN:1824-8039, Proceedings of 37th International Cosmic Ray Conference (ICRC2021)

Published
2022

30. ASTRI Mini-Array Core Science at the Observatorio del Teide

Author

S. Vercellone, C. Bigongiari, A. Burtovoi, M. Cardillo, O. Catalano, A. Franceschini, S. Lombardi, L. Nava, F. Pintore, A. Stamerra, F. Tavecchio, L. Zampieri, R. Alves Batista, E. Amato, L.A. Antonelli, C. Arcaro, J. Becerra González, G. Bonnoli, M. Böttcher, G. Brunetti, A.A. Compagnino, S. Crestan, A. D'Aì, M. Fiori, G. Galanti, A. Giuliani, E.M. de Gouveia Dal Pino, J.G. Green, A. Lamastra, M. Landoni, F. Lucarelli, G. Morlino, B. Olmi, E. Peretti, G. Piano, G. Ponti, E. Poretti, P. Romano, F.G. Saturni, S. Scuderi, A. Tutone, G. Umana, J.A. Acosta-Pulido, P. Barai, A. Bonanno, G. Bonanno, P. Bruno, A. Bulgarelli, V. Conforti, A. Costa, G. Cusumano, M. Del Santo, M.V. del Valle, R. Della Ceca, D.A. Falceta-Gonçalves, V. Fioretti, S. Germani, R.J. García-López, A. Ghedina, F. Gianotti, V. Giordano, M. Kreter, F. Incardona, S. Iovenitti, A. La Barbera, N. La Palombara, V. La Parola, G. Leto, F. Longo, A. López-Oramas, M.C. Maccarone, S. Mereghetti, R. Millul, G. Naletto, A. Pagliaro, N. Parmiggiani, C. Righi, J.C. Rodríguez-Ramírez, G. Romeo, P. Sangiorgi, R. Santos de Lima, G. Tagliaferri, V. Testa, G. Tosti, M. Vázquez Acosta, N. Żywucka, P.A. Caraveo, and G. Pareschi

Subjects
ASTRI, Imaging atmospheric Cherenkov arrays, Very high-energy gamma ray astrophysics, Astroparticle, High Energy Astrophysical Phenomena (astro-ph.HE), Space and Planetary Science, FOS: Physical sciences, Astronomy and Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics, Instrumentation and Methods for Astrophysics (astro-ph.IM)
Abstract

The ASTRI (Astrofisica con Specchi a Tecnologia Replicante Italiana) Project led by the Italian National Institute for Astrophysics (INAF) is developing and will deploy at the Observatorio del Teide a mini-array (ASTRI Mini-Array) composed of nine telescopes similar to the small-size dual-mirror Schwarzschild-Couder telescope (ASTRI-Horn) currently operating on the slopes of Mt. Etna in Sicily. The ASTRI Mini-Array will surpass the current Cherenkov telescope array differential sensitivity above a few tera-electronvolt (TeV), extending the energy band well above hundreds of TeV. This will allow us to explore a new window of the electromagnetic spectrum, by convolving the sensitivity performance with excellent angular and energy resolution figures. In this paper we describe the Core Science that we will address during the first four years of operation, providing examples of the breakthrough results that we will obtain when dealing with current open questions, such as the acceleration of cosmic rays, cosmology and fundamental physics and the new window, for the TeV energy band, of the time-domain astrophysics., Comment: Published in Journal of High Energy Astrophysics. 46 Figures, 7 Tables

Published
2022
Full Text
View/download PDF

32. Extraction of the Muon Signals Recorded with the Surface Detector of the Pierre Auger Observatory Using Recurrent Neural Networks

Author

Jose Chinellato, Marvin Gottowik, Dariusz Gora, Eric Mayotte, A. Gorgi, M. Gómez Berisso, Alan Coleman, S. J. Saffi, Ioana Caracas, R. C. Shellard, R.J. Barreira Luz, Miroslav Pech, M. Pothast, Pavel Horvath, A. Letessier-Selvon, Mario Buscemi, G. De Mauro, A. Tapia, Jörg R. Hörandel, I. Lhenry-Yvon, P. Ruehl, L. Valore, H. Gemmeke, Lorenzo Cazon, C. Pérez Bertolli, M. Suárez-Durán, M. Unger, E. M. Santos, Sullivan Marafico, Clara Keiko Oliveira Watanabe, Serguei Vorobiov, Marco Giammarchi, Jon Paul Lundquist, A. Menshikov, R. Alves Batista, Bruce R. Dawson, F. Pedreira, Sofia Andringa, Julien Manshanden, Andres Travaini, E. Varela, J.D. Sanabria Gomez, Roberto Mussa, Frank G. Schröder, P.O. Mazur, Marina Scornavacche, Jonathan Biteau, F. Salamida, A. Yushkov, Paul Sommers, Maximilian Reininghaus, Raul Sarmento, Felix Schlüter, Fabian Gobbi, Ioana Codrina Maris, Violet M. Harvey, D. Harari, Martina Bohacova, G. P. Guedes, Toshihiro Fujii, Jakub Juryšek, John Farmer, D. Nitz, G. Cataldi, V. Scherini, J. Rautenberg, M. Risse, Jonathan Blazek, Q. Luce, Juan Pablo Gongora, Alena Bakalova, K. Choi, Esteban Roulet, D. Melo, M. Schimp, H. J. Mathes, A. Puyleart, Stanislav Michal, Corinne Berat, M. Giller, Orazio Zapparrata, B. C. Manning, Marcio Aparecido Muller, Maria-Teresa Dova, Markus Roth, R. Sato, Lourenco Lopes, P. Abreu, D. Ravignani, G. Golup, N. Kunka, T. Bister, Maria Rita Coluccia, G. C. Hill, Maximilian Stadelmaier, J. F. Valdés Galicia, I. De Mitri, N. Fazzini, Petr Hamal, Ana Martina Botti, Francesco Fenu, Steffen Hahn, Juan Carlos D'Olivo, T. Pierog, Antonio Condorelli, Alina Mihaela Badescu, Cristina Galea, Jonas Glombitza, F. C. T. Barbato, M. Prouza, Justin M. Albury, P. L. Ghia, L. R. Wiencke, S. Schröder, Niklas Langner, Italo Epicoco, G. Parente, Fabrizia Canfora, Jose J. Gonzalez, Dusan Mandat, Ralph Engel, J. Ridky, J. Rodriguez Rojo, Fridtjof Feldbusch, Enrique Zas, Lorenzo Caccianiga, L. Zehrer, Thomas Hebbeker, M. A. Leigui de Oliveira, Sergio Dasso, Tristan Sudholz, M. I. Micheletti, J. Chudoba, F. Riehn, Carola Dobrigkeit, M. Muzio, V. Novotny, A.L. Garcia Vegas, C. M. Schäfer, Marcel Köpke, M. Platino, François Montanet, A. Insolia, M. Kleifges, D. Zavrtanik, Fernando Contreras, Valerio Verzi, B. Tome, Martín Miguel Freire, Rossella Caruso, B. L. Lago, A. Lucero, Fernando Catalani, Bjarni Pont, E.E. Pereira Martins, J. de Oliveira, J. Pȩkala, Alejandro Almela, Jaime Alvarez-Muñiz, Alexandru Gherghel-Lascu, Brian Fick, Josina Schulte, V. Pirronello, C. J.W.P. Timmermans, Martin Vacula, Julian Kemp, Philipp Papenbreer, Rúben Conceição, M. E. Bertaina, Alan Watson, M. Perlin, Mihai Niculescu-Oglinzanu, L. Bonneau Arbeletche, G. Marsella, Petr Travnicek, Paula Gina Isar, Peter Hansen, W. M. Namasaka, M. Mastrodicasa, Carla Bleve, Rodrigo Guedes Lang, David Wittkowski, Lukáš Vaclavek, Belén Andrada, A. C. Rovero, Eleonora Guido, G. Mancarella, Jesús Peña-Rodríguez, B. Keilhauer, G. Salina, Olivier Deligny, Trent D. Grubb, F. Guarino, John Matthews, Peter Buchholz, Heino Falcke, Alexandru Balaceanu, Vladimir Lenok, P. Tobiska, L. Perrone, Alex Kääpä, Magdalena Cerdá, Juan Manuel Figueira, Roberta Colalillo, Carla Aramo, Matías J. Roncoroni, S. J. Sciutto, R.C. dos Anjos, A. G. Mariazzi, Adriana Vásquez-Ramírez, Vincenzo Rizi, Julien Souchard, D. Martello, J. Vicha, Hernán Asorey, A. Di Matteo, Juan Miguel Carceller, Silvia Mollerach, Flavia Gesualdi, Tomáš Fodran, Alina Nasr-Esfahani, M. Palatka, Xavier Bertou, Marco Aglietta, O. Martínez Bravo, B. Wundheiler, A. Zepeda, Miroslav Hrabovský, Pedro Assis, H. Martinez, A. Etchegoyen, Jeffrey A. Johnsen, L. Lu, H. Schieler, Ugo Giaccari, N. González, A. Segreto, J. F. Soriano, Günter Sigl, Antonella Castellina, A. Haungs, P. Stassi, Radomir Smida, A. Machado Payeras, Thomas Bretz, Gaia Silli, A. Filipčič, Kai Daumiller, F. Sanchez, Petr Janecek, Corbin Covault, F. Sarazin, Srijan Sehgal, Matías Rolf Hampel, Fernando Gollan, S. Petrera, Marc Weber, F. de Palma, P. Mantsch, Lino Miramonti, V. de Souza, D. de Oliveira Franco, G. Matthiae, Z. Szadkowski, Christian Sarmiento-Cano, P. Savina, W. Rodrigues de Carvalho, Antonio Bueno, G. Farrar, T. Huege, Jeffrey Brack, Olaf Scholten, Humberto Ibarguen Salazar, R. M. de Almeida, Gualberto Avila, Octavian Sima, Nataliia Borodai, Miguel Mostafa, A. Fuster, Samo Stanič, D. Lo Presti, D. Correia dos Santos, Isabel Goos, D. Heck, Rodrigo Pelayo, S. J. De Jong, L. Nellen, L. Anchordoqui, A. Taboada, Stijn Buitink, Katie Mulrey, M. del Río, Jarryd A. Day, A. Saftoiu, P.F. Gómez Vitale, C. Morello, A.C. Cobos Cerutti, T. Suomijärvi, D. Nosek, E. Santos, J. Pallotta, J. R. T. de Mello Neto, A. Weindl, Peter L. Biermann, David Schmidt, Paolo Privitera, Hernan Wahlberg, Darko Veberič, A. Parra, M. Schimassek, C. Hojvat, Jan Ebr, Jacco Vink, H.O. Klages, M. Trini, A. A. Nucita, J. Kleinfeller, Carlos Escobar, Kevin-Druis Merenda, A.D. Supanitsky, P.G. Brichetto Orchera, I. Allekotte, A. C. Fauth, Carla Bonifazi, Jose A. Bellido, Fabio Convenga, I.D. Vergara Quispe, J. Stasielak, K.-H. Becker, M. Pimenta, Denise Boncioli, P.R. Araújo Ferreira, Tobias Winchen, Florian Lukas Briechle, A. Aab, K. H. Kampert, J. C. Arteaga Velázquez, J. Perez Armand, Carla Taricco, C. Trimarelli, Matias Tueros, Claudio Galelli, B. García, R. López, Karen S. Caballero-Mora, Luis A. Nunez, Marcus Niechciol, Martin Erdmann, J. de Jesús, A. Streich, Gioacchino Alex Anastasi, M. Wirtz, Roger W Clay, S. Querchfeld, Olena Tkachenko, J. Šupík, Carlo Ventura, Ladislav Chytka, J. Hulsman, R. Squartini, Alfred Müller, G. Medina-Tanco, M. Zavrtanik, E. De Vito, Giovanni Consolati, C. J. Todero Peixoto, Petr Schovanek, Denis Stanca, H. Wilczyński, Ralf Ulrich, L. Nožka, Physics, Aab, A., Abreu, P., Aglietta, M., Albury, J. M., Allekotte, I., Almela, A., Alvarez-Muniz, J., Batista, R. A., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Ferreira, P. R. A., Velazquez, J. C. A., Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Luz, R. J. B., Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Bister, T., Biteau, J., Blazek, J., Bleve, C., Bohacova, M., Boncioli, D., Bonifazi, C., Arbeletche, L. B., Borodai, N., Botti, A. M., Brack, J., Bretz, T., Orchera, P. G. B., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero-Mora, K. S., Caccianiga, L., Canfora, F., Caracas, I., Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Choi, K., Chudoba, J., Chytka, L., Clay, R. W., Cerutti, A. C. C., Colalillo, R., Coleman, A., Coluccia, M. R., Conceicao, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., dos Santos, D. C., Covault, C. E., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., de Almeida, R. M., de Jesus, J., de Jong, S. J., de Mauro, G., de Mello Neto, J. R. T., de Mitri, I., de Oliveira, J., de Oliveira Franco, D., de Palma, F., de Souza, V., de Vito, E., del Rio, M., Deligny, O., Di Matteo, A., Dobrigkeit, C., D'Olivo, J. C., dos Anjos, R. C., Dova, M. T., Ebr, J., Engel, R., Epicoco, I., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fick, B., Figueira, J. M., Filipcic, A., Fodran, T., Freire, M. M., Fujii, T., Fuster, A., Galea, C., Galelli, C., Garcia, B., Vegas, A. L. G., Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Giller, M., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Berisso, M. G., Vitale, P. F. G., Gongora, J. P., Gonzalez, J. M., Gonzalez, N., Goos, I., Gora, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Hill, G. C., Hojvat, C., Horandel, J. R., Horvath, P., Hrabovsky, M., Huege, T., Hulsman, J., Insolia, A., Isar, P. G., Janecek, P., Johnsen, J. A., Jurysek, J., Kaapa, A., Kampert, K. H., Keilhauer, B., Kemp, J., Klages, H. O., Kleifges, M., Kleinfeller, J., Kopke, M., Kunka, N., Lago, B. L., Lang, R. G., Langner, N., de Oliveira, M. A. L., Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Lo Presti, D., Lopes, L., Lopez, R., Lu, L., Luce, Q., Lucero, A., Lundquist, J. P., Payeras, A. M., Mancarella, G., Mandat, D., Manning, B. C., Manshanden, J., Mantsch, P., Marafico, S., Mariazzi, A. G., Maris, I. C., Marsella, G., Martello, D., Martinez, H., Bravo, O. M., Mastrodicasa, M., Mathes, H. J., Matthews, J., Matthiae, G., Mayotte, E., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Merenda, K. -D., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morello, C., Mostafa, M., Muller, A. L., Muller, M. A., Mulrey, K., Mussa, R., Muzio, M., Namasaka, W. M., Nasr-Esfahani, A., Nellen, L., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nozka, L., Nucita, A., Nunez, L. A., Palatka, M., Pallotta, J., Papenbreer, P., Parente, G., Parra, A., Pech, M., Pedreira, F., Pekala, J., Pelayo, R., Pena-Rodriguez, J., Martins, E. E. P., Armand, J. P., Bertolli, C. P., Perlin, M., Perrone, L., Petrera, S., Pierog, T., Pimenta, M., Pirronello, V., Platino, M., Pont, B., Pothast, M., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Rizi, V., de Carvalho, W. R., Rojo, J. R., Roncoroni, M. J., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saffi, S. J., Saftoiu, A., Salamida, F., Salazar, H., Salina, G., Gomez, J. D. S., Sanchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sarmiento-Cano, C., Sato, R., Savina, P., Schafer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schluter, F., Schmidt, D., Scholten, O., Schovanek, P., Schroder, F. G., Schroder, S., Schulte, J., Sciutto, S. J., Scornavacche, M., Segreto, A., Sehgal, S., Shellard, R. C., Sigl, G., Silli, G., Sima, O., Smida, R., Sommers, P., Soriano, J. F., Souchard, J., Squartini, R., Stadelmaier, M., Stanca, D., Stanic, S., Stasielak, J., Stassi, P., Streich, A., Suarez-Duran, M., Sudholz, T., Suomijarvi, T., Supanitsky, A. D., Supik, J., Szadkowski, Z., Taboada, A., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Peixoto, C. J. T., Tome, B., Travaini, A., Travnicek, P., Trimarelli, C., Trini, M., Tueros, M., Ulrich, R., Unger, M., Vaclavek, L., Vacula, M., Galicia, J. F. V., Valore, L., Varela, E., Varma, V., Vasquez-Ramirez, A., Veberic, D., Ventura, C., Quispe, I. D. V., Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Wahlberg, H., Watanabe, C., Watson, A. A., Weber, M., Weindl, A., Wiencke, L., Wilczynski, H., Winchen, T., Wirtz, M., Wittkowski, D., Wundheiler, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., Zehrer, L., Zepeda, A., Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Pierre Auger, Research unit Astroparticle Physics, Alvarez-Mu??iz, J., Alves Batista, R., Ara??jo Ferreira, P. R., Arteaga Vel??zquez, J. C., Barreira Luz, R. J., Boh????ov??, M., Bonneau Arbeletche, L., Brichetto Orchera, P. G., Cobos Cerutti, A. C., Concei????o, R., Correia dos Santos, D., de Jes??s, J., De Mauro, G., De Mitri, I., De Vito, E., del R??o, M., Filip??i??, A., Garc??a, B., Garcia Vegas, A. L., G??mez Berisso, M., G??mez Vitale, P. F., Gonz??lez, J. M., Gonz??lez, N., G??ra, D., H??randel, J. R., Hrabovsk??, M., K????p??, A., K??pke, M., Leigui de Oliveira, M. A., L??pez, R., Machado Payeras, A., Mari??, I. C., Mart??nez Bravo, O., Mostaf??, M., M??ller, A. L., No??ka, L., N????ez, L. A., P??kala, J., Pe??a-Rodriguez, J., Pereira Martins, E. E., Perez Armand, J., P??rez Bertolli, C., Rodrigues de Carvalho, W., Rodriguez Rojo, J., Sanabria Gomez, J. D., S??nchez, F., Sch??fer, C. M., Schl??ter, F., Schov??nek, P., Schr??der, F. G., Schr??der, S., m??da, R., Stani??, S., Su??rez-Dur??n, M., Suomij??rvi, T., up??k, J., Todero Peixoto, C. J., Tom??, B., Vald??s Galicia, J. F., Varma K. C., V., V??squez-Ram??rez, A., Veberi??, D., Vergara Quispe, I. D., Wilczy??ski, H., High Energy Astrophys. & Astropart. Phys (API, FNWI), Aab A., Abreu P., Aglietta M., Albury J.M., Allekotte I., Almela A., Alvarez-Muniz J., Batista R.A., Anastasi G.A., Anchordoqui L., Andrada B., Andringa S., Aramo C., Ferreira P.R.A., Velazquez J.C.A., Asorey H., Assis P., Avila G., Badescu A.M., Bakalova A., Balaceanu A., Barbato F., Luz R.J.B., Becker K.H., Bellido J.A., Berat C., Bertaina M.E., Bertou X., Biermann P.L., Bister T., Biteau J., Blazek J., Bleve C., Bohacova M., Boncioli D., Bonifazi C., Arbeletche L.B., Borodai N., Botti A.M., Brack J., Bretz T., Orchera P.G.B., Briechle F.L., Buchholz P., Bueno A., Buitink S., Buscemi M., Caballero-Mora K.S., Caccianiga L., Canfora F., Caracas I., Carceller J.M., Caruso R., Castellina A., Catalani F., Cataldi G., Cazon L., Cerda M., Chinellato J.A., Choi K., Chudoba J., Chytka L., Clay R.W., Cerutti A.C.C., Colalillo R., Coleman A., Coluccia M.R., Conceicao R., Condorelli A., Consolati G., Contreras F., Convenga F., dos Santos D.C., Covault C.E., Dasso S., Daumiller K., Dawson B.R., Day J.A., de Almeida R.M., de Jesus J., de Jong S.J., de Mauro G., de Mello Neto J.R.T., de Mitri I., de Oliveira J., de Oliveira Franco D., de Palma F., de Souza V., de Vito E., del Rio M., Deligny O., Di Matteo A., Dobrigkeit C., D'Olivo J.C., dos Anjos R.C., Dova M.T., Ebr J., Engel R., Epicoco I., Erdmann M., Escobar C.O., Etchegoyen A., Falcke H., Farmer J., Farrar G., Fauth A.C., Fazzini N., Feldbusch F., Fenu F., Fick B., Figueira J.M., Filipcic A., Fodran T., Freire M.M., Fujii T., Fuster A., Galea C., Galelli C., Garcia B., Vegas A.L.G., Gemmeke H., Gesualdi F., Gherghel-Lascu A., Ghia P.L., Giaccari U., Giammarchi M., Giller M., Glombitza J., Gobbi F., Gollan F., Golup G., Berisso M.G., Vitale P.F.G., Gongora J.P., Gonzalez J.M., Gonzalez N., Goos I., Gora D., Gorgi A., Gottowik M., Grubb T.D., Guarino F., Guedes G.P., Guido E., Hahn S., Hamal P., Hampel M.R., Hansen P., Harari D., Harvey V.M., Haungs A., Hebbeker T., Heck D., Hill G.C., Hojvat C., Horandel J.R., Horvath P., Hrabovsky M., Huege T., Hulsman J., Insolia A., Isar P.G., Janecek P., Johnsen J.A., Jurysek J., Kaapa A., Kampert K.H., Keilhauer B., Kemp J., Klages H.O., Kleifges M., Kleinfeller J., Kopke M., Kunka N., Lago B.L., Lang R.G., Langner N., de Oliveira M.A.L., Lenok V., Letessier-Selvon A., Lhenry-Yvon I., Lo Presti D., Lopes L., Lopez R., Lu L., Luce Q., Lucero A., Lundquist J.P., Payeras A.M., Mancarella G., Mandat D., Manning B.C., Manshanden J., Mantsch P., Marafico S., Mariazzi A.G., Maris I.C., Marsella G., Martello D., Martinez H., Bravo O.M., Mastrodicasa M., Mathes H.J., Matthews J., Matthiae G., Mayotte E., Mazur P.O., Medina-Tanco G., Melo D., Menshikov A., Merenda K.-D., Michal S., Micheletti M.I., Miramonti L., Mollerach S., Montanet F., Morello C., Mostafa M., Muller A.L., Muller M.A., Mulrey K., Mussa R., Muzio M., Namasaka W.M., Nasr-Esfahani A., Nellen L., Niculescu-Oglinzanu M., Niechciol M., Nitz D., Nosek D., Novotny V., Nozka L., Nucita A., Nunez L.A., Palatka M., Pallotta J., Papenbreer P., Parente G., Parra A., Pech M., Pedreira F., Pekala J., Pelayo R., Pena-Rodriguez J., Martins E.E.P., Armand J.P., Bertolli C.P., Perlin M., Perrone L., Petrera S., Pierog T., Pimenta M., Pirronello V., Platino M., Pont B., Pothast M., Privitera P., Prouza M., Puyleart A., Querchfeld S., Rautenberg J., Ravignani D., Reininghaus M., Ridky J., Riehn F., Risse M., Rizi V., de Carvalho W.R., Rojo J.R., Roncoroni M.J., Roth M., Roulet E., Rovero A.C., Ruehl P., Saffi S.J., Saftoiu A., Salamida F., Salazar H., Salina G., Gomez J.D.S., Sanchez F., Santos E.M., Santos E., Sarazin F., Sarmento R., Sarmiento-Cano C., Sato R., Savina P., Schafer C.M., Scherini V., Schieler H., Schimassek M., Schimp M., Schluter F., Schmidt D., Scholten O., Schovanek P., Schroder F.G., Schroder S., Schulte J., Sciutto S.J., Scornavacche M., Segreto A., Sehgal S., Shellard R.C., Sigl G., Silli G., Sima O., Smida R., Sommers P., Soriano J.F., Souchard J., Squartini R., Stadelmaier M., Stanca D., Stanic S., Stasielak J., Stassi P., Streich A., Suarez-Duran M., Sudholz T., Suomijarvi T., Supanitsky A.D., Supik J., Szadkowski Z., Taboada A., Tapia A., Taricco C., Timmermans C., Tkachenko O., Tobiska P., Peixoto C.J.T., Tome B., Travaini A., Travnicek P., Trimarelli C., Trini M., Tueros M., Ulrich R., Unger M., Vaclavek L., Vacula M., Galicia J.F.V., Valore L., Varela E., Varma V., Vasquez-Ramirez A., Veberic D., Ventura C., Quispe I.D.V., Verzi V., Vicha J., Vink J., Vorobiov S., Wahlberg H., Watanabe C., Watson A.A., Weber M., Weindl A., Wiencke L., Wilczynski H., Winchen T., Wirtz M., Wittkowski D., Wundheiler B., Yushkov A., Zapparrata O., Zas E., Zavrtanik D., Zavrtanik M., Zehrer L., and Zepeda A.

Subjects
Photon, Physics::Instrumentation and Detectors, Astronomy, Electron, 01 natural sciences, High Energy Physics - Experiment, Auger, High Energy Physics - Experiment (hep-ex), mass [cosmic radiation], surface [detector], Observatory, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], photon: cosmic radiation, Instrumentation, Mathematical Physics, Physics, AGASA, Settore FIS/01 - Fisica Sperimentale, Detector, cosmic radiation [photon], Astrophysics::Instrumentation and Methods for Astrophysics, Monte Carlo [numerical calculations], electromagnetic [showers], observatory, cosmic radiation [electron], Analysis and statistical methods, numerical calculations: Monte Carlo, Analysis and statistical method, performance, positron: cosmic radiation, atmosphere [showers], Cherenkov detector, data analysis method, Calibration and fitting methods, Cherenkov detectors, Cluster finding, Large detector systems for particle and astroparticle physics, Pattern recognition, Cherenkov counter: water, air, neural network, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, Cosmic ray, cosmic radiation [positron], cosmic radiation: mass, Calibration and fitting method, Nuclear physics, statistical analysis, 0103 physical sciences, showers: electromagnetic, ddc:530, ddc:610, High Energy Physics, 010306 general physics, Zenith, Pierre Auger Observatory, cosmic radiation [muon], Muon, showers: atmosphere, 010308 nuclear & particles physics, detector: surface, hep-ex, water [Cherenkov counter], electron: cosmic radiation, Recurrent neural network, muon: cosmic radiation, Large detector systems for particle and astroparticle physic, Experimental High Energy Physics, High Energy Physics::Experiment, RAIOS CÓSMICOS, experimental results
Abstract

The Pierre Auger Observatory, at present the largest cosmic-ray observatory ever built, is instrumented with a ground array of 1600 water-Cherenkov detectors, known as the Surface Detector (SD). The SD samples the secondary particle content (mostly photons, electrons, positrons and muons) of extensive air showers initiated by cosmic rays with energies ranging from $10^{17}~$eV up to more than $10^{20}~$eV. Measuring the independent contribution of the muon component to the total registered signal is crucial to enhance the capability of the Observatory to estimate the mass of the cosmic rays on an event-by-event basis. However, with the current design of the SD, it is difficult to straightforwardly separate the contributions of muons to the SD time traces from those of photons, electrons and positrons. In this paper, we present a method aimed at extracting the muon component of the time traces registered with each individual detector of the SD using Recurrent Neural Networks. We derive the performances of the method by training the neural network on simulations, in which the muon and the electromagnetic components of the traces are known. We conclude this work showing the performance of this method on experimental data of the Pierre Auger Observatory. We find that our predictions agree with the parameterizations obtained by the AGASA collaboration to describe the lateral distributions of the electromagnetic and muonic components of extensive air showers., Comment: Published version, 23 pages, 15 figures

Published
2022
Full Text
View/download PDF

33. Atividade antibacteriana do extrato bruto de Bacillus amyloliquefaciens frente a diferentes indicadores.

Author

D. SCHULZ and C. R. V. BATISTA

Subjects
Atividade antibacteriana, Bacillus amyloliquefaciens, Listeria monocytogenes., Nutrition. Foods and food supply, TX341-641
Abstract

O presente estudo teve como objetivo obter um extrato bruto de Bacillus amyloliquefaciens, padronizado pela dosagem de proteínas, e quantificar sua atividade antibacteriana pelo halo de inibição do crescimento de Listeria monocytogenes NCTC 098630, Escherichia coli ATCC 25922, Salmonella typhimurium ATCC 14028, Staphylococcus aureus ATCC 25923, Enterococcus faecalis ATCC 29212 Enterobacter aerogenes ATCC 13048 e Pseudomonas aeruginosa ATCC 9027. O extrato bruto de Bacillus amyloliquefaciens somente apresentou atividade antibacteriana frente Listeria monocytogenes NCTC 098630. Constatou-se que a concentração responsável por 50% da máxima atividade antibacteriana foi 29,22 g do extrato bruto, com um halo de inibição de aproximadamente 4 mm.

Published
2008

34. Bacillus amyloliquefaciens COMO POTENCIAL BIOCONSERVANTE DE ALIMENTOS: DETERMINAÇÃO DO PERFIL DE PROTEÍNAS E AMINOGRAMA

Author

D. SCHULZ, M. R. F. MARQUES, I. C. MÜLLER, and C. R. V. BATISTA

Subjects
Bacillus amyloliquefaciens, antimicrobianos, proteases., Nutrition. Foods and food supply, TX341-641
Abstract

Avaliou-se o perfil de proteínas em gel de poliacrilamida e o aminograma do extrato bruto de Bacillus amyloliquefaciens. O extrato bruto de Bacillus amyloliquefaciens foi obtido por precipitação, centrifugação, diálise e esterilização por filtração. Como microrganismo indicador foi utilizado Listeria monocytogenes NCTC 098630 a 105 UFC/mL. Na determinação da composição global de aminoácidos em eletroforese SDS (10%)/PAGE (7,5 a 20%) foram constatadas seis bandas com pesos moleculares aparentes de: 14,8; 20; 29; 30; 34 e 56,2 kDa e composto principalmente de aminoácidos hidrofóbicos (não polares), incluindo a prolina (446,77 ppm), leucina (11,03 ppm), valina (6,27 ppm), isoleucina (4,59 ppm), alanina (2,91 ppm) e glicina (1,87 ppm). Os resultados obtidos sugerem que o extrato bruto de Bacillus amyloliquefaciens é composto principalmente de proteases e outras enzimas bacteriolíticas.

Published
2008

35. Non-Conventional Cuts in Batch Distillation to Brazilian Spirits (cachaça) Production: A Computational Simulation Approach

Author

Lhucas Tenorio de Melo de Sousa, Simone Monteiro e Silva, and Fabio R. M. Batista

Subjects
Process Chemistry and Technology, batch distillation, Aspen Plus, ethanol, vapor–liquid equilibria, thermodynamic, Chemical Engineering (miscellaneous), Bioengineering
Abstract

In this work, an algorithm was developed to determine different possibilities of distillation cuts to support productivity and improve the final quality of cachaça, a Brazilian spirit beverage. The distillation process was simulated using the Aspen Plus® software, considering a wide range of fermented musts compositions available in the literature obtained by fermentation with different yeast strains. Twenty-four simulations were carried out considering eight compounds as follows: water and ethanol (major compounds); acetic acid, acetaldehyde, ethyl acetate, 1-propanol, isobutanol, and isoamyl alcohol (minor compounds). The calculations considered a long-time process, i.e., until almost all the ethanol in the fermented must was distilled. The algorithm enabled the identification of countless distilling cuts, resulting in products with different alcoholic grades and process yields. One fermented must became viable to produce cachaça after the suggested non-traditional method of cuts proposed in this work. Furthermore, the non-traditional distilling cut provided a productivity gain of more than 50%. Finally, the ratio of acetaldehyde and ethanol concentration was the key parameter to determine whether the fermented musts could provide products meeting cachaça’s legislation.

Published
2022
Full Text
View/download PDF

36. Nutritional influences on biomass behaviour and metabolic products by Chlamydomonas reinhardtii

Author

Letícia, de M Sousa, Juliana, de S Ferreira, Vicelma L, Cardoso, and Fabiana R X, Batista

Subjects
Ethanol, Heterotrophic Processes, Biomass, Carbon, Chlamydomonas reinhardtii
Abstract

The recent works have shown the unicellular green alga Chlamydomonas reinhardtii is a relevant model for investigations of algal bioprocesses. In the current work, several media were evaluated in batch mode for a better understanding of C. reinhardtii metabolism. Nutrient-suppression using heterotrophic and mixotrophic conditions were performed. The findings showed C. reinhardtii metabolized lactose (from milk whey permeate) resulting in high biomass density (2.08 g/L) and total chlorophyll content (86.74 mg/m

Published
2021

37. Conformational flexibility of GRASPs and their constituent PDZ subdomains reveals structural basis of their promiscuous interactome

Author

Antonio J. Costa-Filho, Luis Felipe S. Mendes, Christina Redfield, Mariana R. B. Batista, Peter J. Judge, and Anthony Watts

Subjects
0301 basic medicine, Protein Conformation, PDZ domain, Stacking, PDZ Domains, Sequence Homology, Molecular Dynamics Simulation, Crystallography, X-Ray, Biochemistry, Interactome, 03 medical and health sciences, symbols.namesake, Molecular dynamics, 0302 clinical medicine, Humans, Amino Acid Sequence, Molecular Biology, Protein secondary structure, Secretory pathway, Chemistry, Golgi Matrix Proteins, Cell Biology, Golgi apparatus, 030104 developmental biology, 030220 oncology & carcinogenesis, Helix, symbols, Biophysics, Protein Binding
Abstract

The Golgi complex is a central component of the secretory pathway, responsible for several critical cellular functions in eukaryotes. The complex is organized by the Golgi matrix that includes the Golgi reassembly and stacking protein (GRASP), which was shown to be involved in cisternae stacking and lateral linkage in metazoan. GRASPs also have critical roles in other processes, with an unusual ability to interact with several different binding partners. The conserved N terminus of the GRASP family includes two PSD-95, DLG, and ZO-1 (PDZ) domains. Previous crystallographic studies of orthologues suggest that PDZ1 and PDZ2 have similar conformations and secondary structure content. However, PDZ1 alone mediates nearly all interactions between GRASPs and their partners. In this work, NMR, synchrotron radiation CD, and molecular dynamics (MD) were used to examine the structure, flexibility, and stability of the two constituent PDZ domains. GRASP PDZs are structured in an unusual β3 α1 β4 β5 α2 β6 β1 β2 secondary structural arrangement and NMR data indicate that the PDZ1 binding pocket is formed by a stable β2 -strand and a more flexible and unstable α2 -helix, suggesting an explanation for the higher PDZ1 promiscuity. The conformational free energy profiles of the two PDZ domains were calculated using MD simulations. The data suggest that, after binding, the protein partner significantly reduces the conformational space that GRASPs can access by stabilizing one particular conformation, in a partner-dependent fashion. The structural flexibility of PDZ1, modulated by PDZ2, and the coupled, coordinated movement between the two PDZs enable GRASPs to interact with multiple partners, allowing them to function as promiscuous, multitasking proteins.

Published
2020
Full Text
View/download PDF

38. Structural and thermodynamic analyses of human TMED1 (p24γ1) Golgi dynamics

Author

Mariana R. B. Batista, Antonio J. Costa-Filho, M. Cristina Nonato, Danielly C. A. M. Mota, Luis G.M. Basso, Luis F.S. Mendes, Renan M. Mori, and Iara Aimê Cardoso

Subjects
Dimer, Endoplasmic reticulum, Vesicular Transport Proteins, Golgi Apparatus, General Medicine, Golgi apparatus, Biochemistry, Transmembrane protein, Molecular Docking Simulation, chemistry.chemical_compound, Molecular dynamics, symbols.namesake, Secretory protein, chemistry, Protein Domains, symbols, Biophysics, Compartment (development), Humans, Thermodynamics, Lipid bilayer, Secretory pathway, Phylogeny
Abstract

The transmembrane emp24 domain-containing (TMED) proteins, also called p24 proteins, are members of a family of sorting receptors present in all representatives of the Eukarya and abundantly present in all subcompartments of the early secretory pathway, namely the endoplasmic reticulum (ER), the Golgi, and the intermediate compartment. Although essential during the bidirectional transport between the ER and the Golgi, there is still a lack of information regarding the TMED's structure across different subfamilies. Besides, although the presence of a TMED homo-oligomerization was suggested previously based on crystallographic contacts observed for the isolated Golgi Dynamics (GOLD) domain, no further analyses of its presence in solution were done. Here, we describe the first high-resolution structure of a TMED1 GOLD representative and its biophysical characterization in solution. The crystal structure showed a dimer formation that is also present in solution in a salt-dependent manner, suggesting that the GOLD domain can form homodimers in solution even in the absence of the TMED1 coiled-coil region. A molecular dynamics description of the dimer stabilization, with a phylogenetic analysis of the residues important for the oligomerization and a model for the orientation towards the lipid membrane, are also presented.

Published
2021

39. Resurrecting Golgi proteins to grasp Golgi ribbon formation and self-association under stress

Author

Mariana R. B. Batista, Mariana C. Micheletto, Lucas Bleicher, Antonio J. Costa-Filho, Emanuel Kava, and Luis F.S. Mendes

Subjects
Models, Molecular, Subfamily, Protein Conformation, Golgi ribbon formation, Golgi Apparatus, Context (language use), Biology, Biochemistry, symbols.namesake, Structure-Activity Relationship, Structural Biology, Stress, Physiological, Gene duplication, Organelle, Secretion, Amino Acid Sequence, Molecular Biology, Mitosis, Secretory pathway, Phylogeny, Unconventional protein secretion, Golgi Matrix Proteins, General Medicine, Golgi apparatus, Cell biology, body regions, Protein Transport, symbols, Thermodynamics, Hydrophobic and Hydrophilic Interactions, Protein Binding
Abstract

The Golgi complex is a membranous organelle located in the heart of the eukaryotic secretory pathway. A subfamily of the Golgi matrix proteins, called GRASPs, are key players in the stress-induced unconventional secretion, the Golgi dynamics during mitosis/apoptosis, and Golgi ribbon formation. The Golgi ribbon is vertebrate-specific and correlates with the appearance of two GRASP paralogs (GRASP55/GRASP65) and two coiled-coil Golgins (GM130/Golgin45), which interact with each otherin vivo. Although essential for the Golgi ribbon formation and the increase in Golgi structural complexity, the molecular details leading to their appearance only in this subphylum are still unknown. Moreover, despite the new functionalities supported by the GRASP paralogy, little is known about the structural and evolutionary differences between these paralogues. In this context, we used ancestor sequence reconstruction and several biophysical/biochemical approaches to assess the evolution of the GRASP structure, flexibility, and how they started anchoring their Golgin partners. Our data showed that the Golgins appeared in evolution and were anchored by the single GRASP ancestor beforegoraspgene duplication and divergence in Metazoans. After thegoraspdivergence, variations inside the GRASP binding pocket determined which paralogue would recruit each Golgin partner (GRASP55 with Golgin45 and GRASP65 with GM130). These interactions are responsible for the protein’s specific Golgi locations and the appearance of the Golgi ribbon. We also suggest that the capacity of GRASPs to form supramolecular structures is a long-standing feature, which likely affects GRASP’s participation as a trigger of the stress-induced secretory pathway.

Published
2021

40. Metformin effect in models of inflammation is associated with activation of ATP-dependent potassium channels and inhibition of tumor necrosis factor-α production

Author

Paulo S A, Augusto, Tamires C, Matsui, Alysson V, Braga, Felipe F, Rodrigues, Marcela I, Morais, Marcela M G B, Dutra, Carla R A, Batista, Ivo S F, Melo, Sarah O A M, Costa, Caryne M, Bertollo, Márcio M, Coelho, and Renes R, Machado

Subjects
Inflammation, Potassium Channels, Tumor Necrosis Factor-alpha, Carrageenan, Metformin, Disease Models, Animal, Mice, Adenosine Triphosphate, Diabetes Mellitus, Type 2, Hyperalgesia, Animals, Edema, Humans, Neuralgia
Abstract

Metformin is an oral hypoglycemic drug widely used in the management of type 2 diabetes mellitus. We have recently demonstrated that metformin exhibits activity in models of nociceptive and neuropathic pain. However, little is known about its effects in experimental models of inflammation and inflammatory pain. Thus, the present study aimed to evaluate the activity of metformin in experimental models of inflammation and inflammatory pain in mice, as well as the underlying mechanisms. Previous (1 h) per os (p.o.) administration of metformin (250, 500 or 1000 mg/kg) inhibited the mechanical allodynia and paw edema induced by intraplantar (i.pl.) injection of carrageenan (600 μg) and also the pleurisy induced by this stimulus (200 μg, intrapleural). In the model of mechanical allodynia and paw edema induced by carrageenan, metformin also exhibited activity when administered after (1 h) the inflammatory stimulus. Metformin (1000 mg/kg) reduced the production of tumor necrosis factor-α induced by i.pl. injection of carrageenan. Metformin antiallodynic effect was not affected by previous administration of naltrexone (5 or 10 mg/kg, intraperitoneal) or cyproheptadine (5 or 10 mg/kg, p.o). However, this effect was abolished by previous administration of glibenclamide (20 or 40 mg/kg, p.o). In conclusion, the results demonstrate the activity of metformin in models of inflammation and inflammatory pain. In addition, the results indicate that the activity of metformin may be mediated by activation of ATP-sensitive potassium channels and reduction of production of inflammatory mediators. Altogether, these results stimulate the conduction of studies aiming to evaluate whether metformin may be repositioned in the treatment of patients with painful and inflammatory disorders.

Published
2021

41. Repulsive Casimir force in stationary axisymmetric spacetimes

Author

V. De La Hoz-Coronell, A. E. Gonçalves, M. C. Baldiotti, and R. C. Batista

Subjects
High Energy Physics - Theory, Quantum Physics, Physics and Astronomy (miscellaneous), FOS: Physical sciences, General Relativity and Quantum Cosmology (gr-qc), QC770-798, Astrophysics, General Relativity and Quantum Cosmology, QB460-466, High Energy Physics - Theory (hep-th), Nuclear and particle physics. Atomic energy. Radioactivity, Quantum Physics (quant-ph), Engineering (miscellaneous)
Abstract

We study the influence of stationary axisymmetric spacetimes on Casimir energy. We consider a massive scalar field and analyze its dependence on the apparatus orientation with respect to the dragging direction associated with such spaces. We show that, for an apparatus orientation not considered before in the literature, the Casimir energy can change its sign, producing a repulsive force. As applications, we analyze two specific metrics: one associated with a linear motion of a cylinder and a circular equatorial motion around a gravitational source described by Kerr geometry., 13 pages, 3 figures, matches the version accepted in Eur. Phys. J. C

Published
2021

42. The FRAM robotic telescope for atmospheric monitoring at the Pierre Auger Observatory

Author

Jose Chinellato, Ioana Caracas, Lorenzo Cazon, C. Pérez Bertolli, Ioana Codrina Maris, Marina Scornavacche, R. Ulrich, G. C. Hill, Jorge F. Soriano, Ralph Engel, M. Risse, H. J. Mathes, J. Ridky, Xavier Bertou, G. Marsella, David Wittkowski, G. Salina, Olivier Deligny, M. Unger, Tomáš Fodran, Alina Nasr-Esfahani, Stanislav Michal, Jonathan Blazek, Ugo Giaccari, J. Kleinfeller, K. Choi, Julien Manshanden, Andres Travaini, E. Varela, J.D. Sanabria Gomez, K.-H. Becker, M. Pimenta, P.R. Araújo Ferreira, Tobias Winchen, Denis Stanca, Florian Lukas Briechle, F. Canfora, G. Farrar, Antonio Condorelli, Carla Bleve, Rodrigo Guedes Lang, G. De Mauro, Silvia Mollerach, N. Fazzini, Jonas Glombitza, F. C. T. Barbato, P. Abreu, D. Ravignani, Alena Bakalova, G. Matthiae, Jaime Alvarez-Muñiz, J. Rodriguez Rojo, Fridtjof Feldbusch, Enrique Zas, Marvin Gottowik, Carlos Escobar, Kevin-Druis Merenda, R.J. Barreira Luz, G. P. Guedes, G. Parente, L. Zehrer, A. Puyleart, Corinne Berat, M. Giller, Jörg R. Hörandel, Paul Sommers, P. Kubánek, Flavia Gesualdi, Fernando Contreras, Alexandru Gherghel-Lascu, Belén Andrada, P. Tobiska, Antonio Bueno, Violet M. Harvey, D. Harari, J. Chudoba, Valerio Pirronello, Gualberto Avila, B. García, Lukáš Vaclavek, Toshihiro Fujii, Dariusz Gora, Eric Mayotte, A. Zepeda, R. López, G. Mancarella, Pedro Assis, H. Martinez, A. Etchegoyen, Matías J. Roncoroni, Martina Bohacova, A. Aab, J. Biteau, I. Lhenry-Yvon, Karen S. Caballero-Mora, A.L. Garcia Vegas, B. Keilhauer, J. de Oliveira, A.D. Supanitsky, M. Gómez Berisso, Jakub Juryšek, Alejandro Almela, R. C. Shellard, S. J. Sciutto, A. Di Matteo, Alan Coleman, S. J. Saffi, B. Wundheiler, Marcel Köpke, Martin Erdmann, J. de Jesús, Juan Miguel Carceller, C. J. Todero Peixoto, Alina Mihaela Badescu, Cristina Galea, John Farmer, Serguei Vorobiov, M. Platino, Maria Rita Coluccia, Carla Taricco, M. Prouza, G. Cataldi, A. Streich, Gioacchino Alex Anastasi, D. Nitz, Juan Pablo Gongora, F. Pedreira, M. I. Micheletti, F. Salamida, M. Wirtz, Petr Hamal, B. L. Lago, P. Ruehl, Fred Sarazin, Thomas Bretz, A. Taboada, V. Scherini, A. Yushkov, Roger W Clay, Clara Keiko Oliveira Watanabe, Matias Tueros, Raul Sarmento, D. Melo, Mario Buscemi, Thomas Hebbeker, Maria-Teresa Dova, Sergio Dasso, Tristan Sudholz, Martin Vacula, Felix Schlüter, Magdalena Cerdá, E.E. Pereira Martins, Steffen Hahn, Juan Carlos D'Olivo, K. H. Kampert, T. Pierog, Fabian Gobbi, Christian Sarmiento-Cano, Hernán Asorey, Martín Miguel Freire, P.F. Gómez Vitale, Heino Falcke, Maximilian Reininghaus, L. R. Wiencke, Niklas Langner, J. C. Arteaga Velázquez, Petr Janecek, Brian Fick, M. Suárez-Durán, J. Vicha, Corbin Covault, Darko Veberič, Matías Rolf Hampel, Esteban Roulet, Rúben Conceição, R. Sato, Paula Gina Isar, J. Rautenberg, D. Nosek, F. Riehn, L. Nožka, Lourenco Lopes, M. Roth, S. Karpov, J. Perez Armand, E. Santos, Jesús Peña-Rodríguez, Q. Luce, Gaia Silli, Dusan Mandat, Justin M. Albury, A. Filipčič, T. Huege, F. Sanchez, Maximilian Stadelmaier, Frank G. Schröder, Lino Miramonti, Luis A. Nunez, A. Gorgi, A. Insolia, M. Kleifges, D. Zavrtanik, J. F. Valdés Galicia, Marcio Aparecido Muller, M. Zavrtanik, Antoine Letessier-Selvon, A. Fuster, L. Valore, I. De Mitri, Jeffrey Brack, S. Petrera, Marc Weber, W. M. Namasaka, M. Mastrodicasa, D. de Oliveira Franco, K. C. V. Varma, E. De Vito, Olaf Scholten, Marcus Niechciol, Humberto Ibarguen Salazar, C. M. Schäfer, A. C. Rovero, Giovanni Consolati, R.C. dos Anjos, Adriana Vásquez-Ramírez, E. M. Santos, A. Weindl, Bjarni Pont, Alexandru Balaceanu, M. A. Leigui de Oliveira, Roberto Mussa, Lorenzo Caccianiga, G. Golup, M. Palatka, R. Alves Batista, Bruce R. Dawson, C. Trimarelli, N. Kunka, H. Wilczyński, Claudio Galelli, L. Lu, Juan Manuel González, Carla Aramo, Vincenzo Rizi, P.O. Mazur, Julien Souchard, V. Novotny, C. J.W.P. Timmermans, D. Lo Presti, Rossella Caruso, A. Lucero, Fernando Catalani, D. Martello, S. J. De Jong, A. Tapia, Petr Schovanek, O. Martínez Bravo, Piera Luisa Ghia, T. Bister, Jon Paul Lundquist, A. Menshikov, H. Gemmeke, David Schmidt, S. Schröder, Italo Epicoco, M. Schimassek, François Montanet, Miguel Mostafa, Julian Kemp, S. Querchfeld, Sullivan Marafico, Olena Tkachenko, C. Hojvat, Jan Ebr, Valerio Verzi, Eleonora Guido, L. Nellen, Jarryd A. Day, A. Saftoiu, Marco Giammarchi, J. Šupík, Carlo Ventura, Octavian Sima, M. Mašek, B. Tome, C. Morello, Luis A. Anchordoqui, Jacco Vink, Alex Kääpä, Philipp Papenbreer, Samo Stanič, H.O. Klages, Petr Travnicek, L. Bonneau Arbeletche, Trent D. Grubb, Ladislav Chytka, A.C. Cobos Cerutti, R. Cunniffe, N. González, J. R. T. de Mello Neto, Peter L. Biermann, Juan Manuel Figueira, Isabel Goos, Roberta Colalillo, A. G. Mariazzi, J. Stasielak, Kai Daumiller, H. Schieler, Paolo Privitera, A. A. Nucita, Antonella Castellina, D. Heck, M. del Río, I. Ebrová, Denise Boncioli, P. Savina, W. Rodrigues de Carvalho, M. Jelínek, Jeffrey A. Johnsen, Nataliia Borodai, A. Segreto, Vladimir Lenok, L. Perrone, J. Hulsman, Günter Sigl, R. Squartini, Alfred Müller, P. Stassi, Radomir Smida, A. Machado Payeras, J. Eliášek, G. Medina-Tanco, Srijan Sehgal, Miroslav Pech, M. Pothast, Fernando Gollan, F. de Palma, Pavel Horvath, V. de Souza, Sofia Andringa, M. Schimp, B. C. Manning, Ana Martina Botti, Francesco Fenu, Miroslav Hrabovský, A. Haungs, Josina Schulte, Peter Hansen, P. Mantsch, Z. Szadkowski, J. Pkala, F. Guarino, John Matthews, Peter Buchholz, Marco Aglietta, R. M. de Almeida, D. Correia dos Santos, Rodrigo Pelayo, Stijn Buitink, Katie Mulrey, Orazio Zapparrata, Carola Dobrigkeit, M. Muzio, M. E. Bertaina, Alan Watson, M. Perlin, Mihai Niculescu-Oglinzanu, T. Suomijärvi, J. Pallotta, A. C. Fauth, Carla Bonifazi, Jose A. Bellido, Fabio Convenga, I.D. Vergara Quispe, Hernan Wahlberg, A. Parra, M. Trini, P.G. Brichetto Orchera, I. Allekotte, High Energy Astrophys. & Astropart. Phys (API, FNWI), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Pierre Auger, Aab, A., Abreu, P., Aglietta, M., Albury, J. M., Allekotte, I., Almela, A., Alvarez-Mu??iz, J., Alves Batista, R., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Ara??jo Ferreira, P. R., Arteaga Vel??zquez, J. C., Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Barreira Luz, R. J., Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Bister, T., Biteau, J., Blazek, J., Bleve, C., Boh????ov??, M., Boncioli, D., Bonifazi, C., Bonneau Arbeletche, L., Borodai, N., Botti, A. M., Brack, J., Bretz, T., Brichetto Orchera, P. G., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero-Mora, K. S., Caccianiga, L., Canfora, F., Caracas, I., Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Choi, K., Chudoba, J., Chytka, L., Clay, R. W., Cobos Cerutti, A. C., Colalillo, R., Coleman, A., Coluccia, M. R., Concei????o, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., Correia dos Santos, D., Covault, C. E., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., de Almeida, R. M., de Jes??s, J., de Jong, S. J., De Mauro, G., de Mello Neto, J. R. T., De Mitri, I., de Oliveira, J., de Oliveira Franco, D., de Palma, F., de Souza, V., De Vito, E., del R??o, M., Deligny, O., Di Matteo, A., Dobrigkeit, C., D'Olivo, J. C., dos Anjos, R. C., Dova, M. T., Ebr, J., Engel, R., Epicoco, I., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fick, B., Figueira, J. M., Filip??i??, A., Fodran, T., Freire, M. M., Fujii, T., Fuster, A., Galea, C., Galelli, C., Garc??a, B., Garcia Vegas, A. L., Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Giller, M., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., G??mez Berisso, M., G??mez Vitale, P. F., Gongora, J. P., Gonz??lez, J. M., Gonz??lez, N., Goos, I., G??ra, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Hill, G. C., Hojvat, C., H??randel, J. R., Horvath, P., Hrabovsk??, M., Huege, T., Hulsman, J., Insolia, A., Isar, P. G., Janecek, P., Johnsen, J. A., Jurysek, J., K????p??, A., Kampert, K. H., Keilhauer, B., Kemp, J., Klages, H. O., Kleifges, M., Kleinfeller, J., K??pke, M., Kunka, N., Lago, B. L., Lang, R. G., Langner, N., Leigui de Oliveira, M. A., Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Lo Presti, D., Lopes, L., L??pez, R., Lu, L., Luce, Q., Lucero, A., Lundquist, J. P., Machado Payeras, A., Mancarella, G., Mandat, D., Manning, B. C., Manshanden, J., Mantsch, P., Marafico, S., Mariazzi, A. G., Mari??, I. C., Marsella, G., Martello, D., Martinez, H., Mart??nez Bravo, O., Mastrodicasa, M., Mathes, H. J., Matthews, J., Matthiae, G., Mayotte, E., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Merenda, K. -D., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morello, C., Mostaf??, M., M??ller, A. L., Muller, M. A., Mulrey, K., Mussa, R., Muzio, M., Namasaka, W. M., Nasr-Esfahani, A., Nellen, L., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., No??ka, L., Nucita, A., N????ez, L. A., Palatka, M., Pallotta, J., Papenbreer, P., Parente, G., Parra, A., Pech, M., Pedreira, F., P??kala, J., Pelayo, R., Pe??a-Rodriguez, J., Pereira Martins, E. E., Perez Armand, J., P??rez Bertolli, C., Perlin, M., Perrone, L., Petrera, S., Pierog, T., Pimenta, M., Pirronello, V., Platino, M., Pont, B., Pothast, M., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Rizi, V., Rodrigues de Carvalho, W., Rodriguez Rojo, J., Roncoroni, M. J., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saffi, S. J., Saftoiu, A., Salamida, F., Salazar, H., Salina, G., Sanabria Gomez, J. D., S??nchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sarmiento-Cano, C., Sato, R., Savina, P., Sch??fer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schl??ter, F., Schmidt, D., Scholten, O., Schov??nek, P., Schr??der, F. G., Schr??der, S., Schulte, J., Sciutto, S. J., Scornavacche, M., Segreto, A., Sehgal, S., Shellard, R. C., Sigl, G., Silli, G., Sima, O., m??da, R., Sommers, P., Soriano, J. F., Souchard, J., Squartini, R., Stadelmaier, M., Stanca, D., Stani??, S., Stasielak, J., Stassi, P., Streich, A., Su??rez-Dur??n, M., Sudholz, T., Suomij??rvi, T., Supanitsky, A. D., up??k, J., Szadkowski, Z., Taboada, A., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Todero Peixoto, C. J., Tom??, B., Travaini, A., Travnicek, P., Trimarelli, C., Trini, M., Tueros, M., Ulrich, R., Unger, M., Vaclavek, L., Vacula, M., Vald??s Galicia, J. F., Valore, L., Varela, E., Varma K. C., V., V??squez-Ram??rez, A., Veberi??, D., Ventura, C., Vergara Quispe, I. D., Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Wahlberg, H., Watanabe, C., Watson, A. A., Weber, M., Weindl, A., Wiencke, L., Wilczy??ski, H., Winchen, T., Wirtz, M., Wittkowski, D., Wundheiler, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., Zehrer, L., Zepeda, A., Cunniffe, R., Eli????ek, J., Ebrov??, I., Jel??nek, M., Karpov, S., Kub??nek, P., Ma??ek, M., Pierre Auger Collaboration, T., Alvarez-Muniz, J., Araujo Ferreira, P. R., Arteaga Velazquez, J. C., Bohacova, M., Conceicao, R., Correia Dos Santos, D., De Almeida, R. M., De Jesus, J., De Jong, S. J., De Mello Neto, J. R. T., De Oliveira, J., De Oliveira Franco, D., De Palma, F., De Souza, V., Del Rio, M., Dos Anjos, R. C., Filipcic, A., Garcia, B., Gomez Berisso, M., Gomez Vitale, P. F., Gonzalez, J. M., Gonzalez, N., Gora, D., Horandel, J. R., Hrabovsky, M., Kaapa, A., Kopke, M., Leigui De Oliveira, M. A., Lopez, R., Maris, I. C., Martinez Bravo, O., Mostafa, M., Muller, A. L., Nozka, L., Nunez, L. A., Pkala, J., Pena-Rodriguez, J., Perez Bertolli, C., Rodrigues De Carvalho, W., Sanchez, F., Schafer, C. M., Schluter, F., Schovanek, P., Schroder, F. G., Schroder, S., Smida, R., Stanic, S., Suarez-Duran, M., Suomijarvi, T., Supik, J., Tome, B., Valdes Galicia, J. F., Varma, K. C. V., Vasquez-Ramirez, A., Veberic, D., Wilczynski, H., Eliasek, J., Ebrova, I., Jelinek, M., Kubanek, P., Masek, M., Research unit Astroparticle Physics, Pierre Auger Collaboration T., Aab A., Abreu P., Aglietta M., Albury J.M., Allekotte I., Almela A., Alvarez-Muniz J., Alves Batista R., Anastasi G.A., Anchordoqui L., Andrada B., Andringa S., Aramo C., Araujo Ferreira P.R., Arteaga Velazquez J.C., Asorey H., Assis P., Avila G., Badescu A.M., Bakalova A., Balaceanu A., Barbato F., Barreira Luz R.J., Becker K.H., Bellido J.A., Berat C., Bertaina M.E., Bertou X., Biermann P.L., Bister T., Biteau J., Blazek J., Bleve C., Bohacova M., Boncioli D., Bonifazi C., Bonneau Arbeletche L., Borodai N., Botti A.M., Brack J., Bretz T., Brichetto Orchera P.G., Briechle F.L., Buchholz P., Bueno A., Buitink S., Buscemi M., Caballero-Mora K.S., Caccianiga L., Canfora F., Caracas I., Carceller J.M., Caruso R., Castellina A., Catalani F., Cataldi G., Cazon L., Cerda M., Chinellato J.A., Choi K., Chudoba J., Chytka L., Clay R.W., Cobos Cerutti A.C., Colalillo R., Coleman A., Coluccia M.R., Conceicao R., Condorelli A., Consolati G., Contreras F., Convenga F., Correia Dos Santos D., Covault C.E., Dasso S., Daumiller K., Dawson B.R., Day J.A., De Almeida R.M., De Jesus J., De Jong S.J., De Mauro G., De Mello Neto J.R.T., De Mitri I., De Oliveira J., De Oliveira Franco D., De Palma F., De Souza V., De Vito E., Del Rio M., Deligny O., Di Matteo A., Dobrigkeit C., D'Olivo J.C., Dos Anjos R.C., Dova M.T., Ebr J., Engel R., Epicoco I., Erdmann M., Escobar C.O., Etchegoyen A., Falcke H., Farmer J., Farrar G., Fauth A.C., Fazzini N., Feldbusch F., Fenu F., Fick B., Figueira J.M., Filipcic A., Fodran T., Freire M.M., Fujii T., Fuster A., Galea C., Galelli C., Garcia B., Garcia Vegas A.L., Gemmeke H., Gesualdi F., Gherghel-Lascu A., Ghia P.L., Giaccari U., Giammarchi M., Giller M., Glombitza J., Gobbi F., Gollan F., Golup G., Gomez Berisso M., Gomez Vitale P.F., Gongora J.P., Gonzalez J.M., Gonzalez N., Goos I., Gora D., Gorgi A., Gottowik M., Grubb T.D., Guarino F., Guedes G.P., Guido E., Hahn S., Hamal P., Hampel M.R., Hansen P., Harari D., Harvey V.M., Haungs A., Hebbeker T., Heck D., Hill G.C., Hojvat C., Horandel J.R., Horvath P., Hrabovsky M., Huege T., Hulsman J., Insolia A., Isar P.G., Janecek P., Johnsen J.A., Jurysek J., Kaapa A., Kampert K.H., Keilhauer B., Kemp J., Klages H.O., Kleifges M., Kleinfeller J., Kopke M., Kunka N., Lago B.L., Lang R.G., Langner N., Leigui De Oliveira M.A., Lenok V., Letessier-Selvon A., Lhenry-Yvon I., Lo Presti D., Lopes L., Lopez R., Lu L., Luce Q., Lucero A., Lundquist J.P., Machado Payeras A., Mancarella G., Mandat D., Manning B.C., Manshanden J., Mantsch P., Marafico S., Mariazzi A.G., Maris I.C., Marsella G., Martello D., Martinez H., Martinez Bravo O., Mastrodicasa M., Mathes H.J., Matthews J., Matthiae G., Mayotte E., Mazur P.O., Medina-Tanco G., Melo D., Menshikov A., Merenda K.-D., Michal S., Micheletti M.I., Miramonti L., Mollerach S., Montanet F., Morello C., Mostafa M., Muller A.L., Muller M.A., Mulrey K., Mussa R., Muzio M., Namasaka W.M., Nasr-Esfahani A., Nellen L., Niculescu-Oglinzanu M., Niechciol M., Nitz D., Nosek D., Novotny V., Nozka L., Nucita A., Nunez L.A., Palatka M., Pallotta J., Papenbreer P., Parente G., Parra A., Pech M., Pedreira F., Pkala J., Pelayo R., Pena-Rodriguez J., Pereira Martins E.E., Perez Armand J., Perez Bertolli C., Perlin M., Perrone L., Petrera S., Pierog T., Pimenta M., Pirronello V., Platino M., Pont B., Pothast M., Privitera P., Prouza M., Puyleart A., Querchfeld S., Rautenberg J., Ravignani D., Reininghaus M., Ridky J., Riehn F., Risse M., Rizi V., Rodrigues De Carvalho W., Rodriguez Rojo J., Roncoroni M.J., Roth M., Roulet E., Rovero A.C., Ruehl P., Saffi S.J., Saftoiu A., Salamida F., Salazar H., Salina G., Sanabria Gomez J.D., Sanchez F., Santos E.M., Santos E., Sarazin F., Sarmento R., Sarmiento-Cano C., Sato R., Savina P., Schafer C.M., Scherini V., Schieler H., Schimassek M., Schimp M., Schluter F., Schmidt D., Scholten O., Schovanek P., Schroder F.G., Schroder S., Schulte J., Sciutto S.J., Scornavacche M., Segreto A., Sehgal S., Shellard R.C., Sigl G., Silli G., Sima O., Smida R., Sommers P., Soriano J.F., Souchard J., Squartini R., Stadelmaier M., Stanca D., Stanic S., Stasielak J., Stassi P., Streich A., Suarez-Duran M., Sudholz T., Suomijarvi T., Supanitsky A.D., Supik J., Szadkowski Z., Taboada A., Tapia A., Taricco C., Timmermans C., Tkachenko O., Tobiska P., Todero Peixoto C.J., Tome B., Travaini A., Travnicek P., Trimarelli C., Trini M., Tueros M., Ulrich R., Unger M., Vaclavek L., Vacula M., Valdes Galicia J.F., Valore L., Varela E., Varma K.C.V., Vasquez-Ramirez A., Veberic D., Ventura C., Vergara Quispe I.D., Verzi V., Vicha J., Vink J., Vorobiov S., Wahlberg H., Watanabe C., Watson A.A., Weber M., Weindl A., Wiencke L., Wilczynski H., Winchen T., Wirtz M., Wittkowski D., Wundheiler B., Yushkov A., Zapparrata O., Zas E., Zavrtanik D., Zavrtanik M., Zehrer L., Zepeda A., Cunniffe R., Eliasek J., Ebrova I., Jelinek M., Karpov S., Kubanek P., Masek M., and Physics

Subjects
Astronomy, Large detector systems for particle and astroparticle physics, Optics, Photon detectors for UV, visible and IR photons (solid-state) (PIN diodes, APDs, Si-PMTs, G-APDs, CCDs, EBCCDs, EMCCDs, CMOS imagers, etc), Real-time monitoring, 01 natural sciences, Auger, Successful operation, Observatory, optical, APDs, hardware, Astrophysics::Solar and Stellar Astrophysics, 010303 astronomy & astrophysics, Instrumentation, Photon detectors for UV, Mathematical Physics, High Energy Astrophysical Phenomena (astro-ph.HE), astro-ph.HE, EBCCDs, Settore FIS/01 - Fisica Sperimentale, Astrophysics::Instrumentation and Methods for Astrophysics, Si-PMTs, observatory, Robotic telescope, G-APDs, Astrophysics::Earth and Planetary Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, Sciences exactes et naturelles, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, programming, detector: fluorescence, Photometry (optics), 0103 physical sciences, ddc:610, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], High Energy Physics, visible and IR photons (solid-state) (PIN diodes, CMOS imagers, Instrumentation and Methods for Astrophysics (astro-ph.IM), Astrophysics::Galaxy Astrophysics, Remote sensing, etc), fluorescence [detector], Pierre Auger Observatory, 010308 nuclear & particles physics, Active monitoring, CCDs, laser, monitoring, EMCCDs, Large detector systems for particle and astroparticle physic, atmosphere, Experimental High Energy Physics, Optic, Environmental science, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], RAIOS CÓSMICOS, astro-ph.IM
Abstract

FRAM (F/Photometric Robotic Atmospheric Monitor) is a robotic telescope operated at the Pierre Auger Observatory in Argentina for the purposes of atmospheric monitoring using stellar photometry. As a passive system which does not produce any light that could interfere with the observations of the fluorescence telescopes of the observatory, it complements the active monitoring systems that use lasers. We discuss the applications of stellar photometry for atmospheric monitoring at optical observatories in general and the particular modes of operation employed by the Auger FRAM. We describe in detail the technical aspects of FRAM, the hardware and software requirements for a successful operation of a robotic telescope for such a purpose and their implementation within the FRAM system., Published version, 27 pages, 8 figures

Published
2021
Full Text
View/download PDF

43. ATIVIDADE ANTIMICROBIANA E HEMOLÃTICA DO EXTRATO BRUTO PRODUZIDO POR Bacillus amyloliquefaciens

Author

D. SCHULZ, M. A. PEREIRA, M. M. NUNES, and C. R. V. BATISTA

Subjects
Atividade antimicrobiana, atividade hemolítica, Bacillus amyloliquefaciens., Nutrition. Foods and food supply, TX341-641
Abstract

Avaliou-se a atividade antimicrobiana e hemolítica do extrato bruto produzido por Bacillus amyloliquefaciens, a ser utilizado como bioconservador em alimentos, previamente padronizado pela dosagem de proteínas; a qual foi quantificada pelo halo de hemólise e inibição do crescimento de Listeria monocytogenes NCTC 098630. As concentrações de proteína responsáveis por 50% da atividade antimicrobiana e hemolítica máxima foram de 22,54 e 20,88 mg (de proteína), respectivamente, sugerindo que a substância antimicrobiana presente no extrato bruto seja relacionada, também com a atividade hemolítica.

Published
2008

44. Toll-like receptor 4 upregulation by angiotensin II contributes to hypertension and vascular dysfunction through reactive oxygen species production.

Author

Priscila R De Batista, Roberto Palacios, Angela Martín, Raquel Hernanz, Cindy T Médici, Marito A S C Silva, Emilly M Rossi, Andrea Aguado, Dalton V Vassallo, Mercedes Salaices, and María J Alonso

Subjects
Medicine, Science
Abstract

Hypertension is considered as a low-grade inflammatory disease, with adaptive immunity being an important mediator of this pathology. TLR4 may have a role in the development of several cardiovascular diseases; however, little is known about its participation in hypertension. We aimed to investigate whether TLR4 activation due to increased activity of the renin-angiotensin system (RAS) contributes to hypertension and its associated endothelial dysfunction. For this, we used aortic segments from Wistar rats treated with a non-specific IgG (1 µg/day) and SHRs treated with losartan (15 mg/kg·day), the non-specific IgG or the neutralizing antibody anti-TLR4 (1 µg/day), as well as cultured vascular smooth muscle cells (VSMC) from Wistar and SHRs. TLR4 mRNA levels were greater in the VSMC and aortas from SHRs compared with Wistar rats; losartan treatment reduced those levels in the SHRs. Treatment of the SHRs with the anti-TLR4 antibody: 1) reduced the increased blood pressure, heart rate and phenylephrine-induced contraction while it improved the impaired acetylcholine-induced relaxation; 2) increased the potentiation of phenylephrine contraction after endothelium removal; and 3) abolished the inhibitory effects of tiron, apocynin and catalase on the phenylephrine-induced response as well as its enhancing effect of acetylcholine-induced relaxation. In SHR VSMCs, angiotensin II increased TLR4 mRNA levels, and losartan reduced that increase. CLI-095, a TLR4 inhibitor, mitigated the increases in NAD(P)H oxidase activity, superoxide anion production, migration and proliferation that were induced by angiotensin II. In conclusion, TLR4 pathway activation due to increased RAS activity is involved in hypertension, and by inducing oxidative stress, this pathway contributes to the endothelial dysfunction associated with this pathology. These results suggest that TLR4 and innate immunity may play a role in hypertension and its associated end-organ damage.

Published
2014
Full Text
View/download PDF

45. Measurement of the Fluctuations in the Number of Muons in Extensive Air Showers with the Pierre Auger Observatory

Author

H. J. Mathes, Stanislav Michal, Miroslav Pech, Antonio Condorelli, M. Pothast, Pavel Horvath, A.L. Garcia Vegas, W. M. Namasaka, A. C. Rovero, M. Risse, J. Rodriguez Rojo, Fridtjof Feldbusch, B. Andrada, Alexandru Balaceanu, Jonathan Blazek, Carla Aramo, Vincenzo Rizi, J. F. Valdés Galicia, Julien Souchard, Sofia Andringa, Enrique Zas, Magdalena Cerdá, Hernán Asorey, I. De Mitri, D. Martello, David Wittkowski, O. Martínez Bravo, K. Mulrey, P. Abreu, D. Ravignani, G. Salina, Danielle LaHurd, Olivier Deligny, Marcel Köpke, M. Platino, Fernando Contreras, A. Tapia, H. Gemmeke, G. Parente, Fabrizia Canfora, L. Zehrer, L. Lopes, Tomáš Fodran, Jaime Alvarez-Muñiz, Alexandru Gherghel-Lascu, M. A. Leigui de Oliveira, Flavia Gesualdi, G. Kukec Mezek, G. Marsella, Valerio Pirronello, R. Lorek, G. De Mauro, M. Unger, Ugo Giaccari, Silvia Mollerach, H. Dembinski, N. Fazzini, Jonas Glombitza, F. C. T. Barbato, Dariusz Gora, M. E. Bertaina, Jon Paul Lundquist, A. Menshikov, K.-H. Becker, M. Pimenta, P.R. Araújo Ferreira, J. de Oliveira, Alejandro Almela, C. J. Todero Peixoto, M. Zavrtanik, Lukáš Vaclavek, W. Rodrigues de Carvalho, Jörg R. Hörandel, B. Keilhauer, Marcus Niechciol, A. C. Fauth, Teresa Bister, J. Chudoba, Alan Coleman, B. Tome, Josina Schulte, S. J. Saffi, Tobias Winchen, Julian Kemp, S. J. Sciutto, Carla Bleve, Rodrigo Guedes Lang, Florian Lukas Briechle, Peter Hansen, Lorenzo Caccianiga, Marvin Gottowik, Julien Manshanden, G. Cataldi, E. De Vito, F. Guarino, John Matthews, I. Lhenry-Yvon, Nataliia Borodai, V. Scherini, Paul Sommers, Peter Buchholz, Andres Travaini, Giovanni Consolati, E. Varela, J.D. Sanabria Gomez, Juan Miguel Carceller, Christian Sarmiento-Cano, R. M. de Almeida, P. Tobiska, Alex Kääpä, F. Pedreira, Carla Bonifazi, D. Lo Presti, Jose A. Bellido, S. J. De Jong, Marco Aglietta, Vladimir Lenok, Eric Mayotte, Raul Sarmento, Fabio Convenga, M. M. Freire, Felix Schlüter, H. Wilczyński, Jeffrey A. Johnsen, Fabian Gobbi, Jose Chinellato, F. Sánchez, Serguei Vorobiov, L. Perrone, Alena Bakalova, E. M. Santos, D. Nitz, R. Squartini, Alfred Müller, Petr Schovanek, Valerio Verzi, A. Fuster, G. Golup, M. Gómez Berisso, R. C. Shellard, Octavian Sima, Jarryd A. Day, A. Saftoiu, A.C. Cobos Cerutti, J. R. T. de Mello Neto, G. Torralba Elipe, R. Alves Batista, Bruce R. Dawson, G. Matthiae, Jesús Peña-Rodríguez, Antonio Bueno, Thomas Hebbeker, Sergio Dasso, Tristan Sudholz, H. Schieler, Antonella Castellina, Maria Rita Coluccia, A. Di Matteo, M. Schimp, B. Wundheiler, B. C. Manning, A. Insolia, M. Kleifges, D. Zavrtanik, A.D. Supanitsky, Fred Sarazin, J. Pȩkala, Ioana Caracas, A. Letessier-Selvon, B. García, R. López, Karen S. Caballero-Mora, P.O. Mazur, Thomas Bretz, Lorenzo Cazon, Darko Veberič, Mario Buscemi, Roberto Mussa, T. Huege, I.D. Vergara Quispe, G. Medina-Tanco, R. Halliday, L. Valore, J. Rautenberg, Jeffrey Brack, Günter Sigl, Olaf Scholten, F. Riehn, Marina Scornavacche, Corbin Covault, Jonathan Biteau, Francesco Fenu, Xavier Bertou, Humberto Ibarguen Salazar, L. R. Wiencke, Rodrigo Pelayo, Stijn Buitink, Niklas Langner, S. Querchfeld, Olena Tkachenko, J. Šupík, Carlo Ventura, Gualberto Avila, Q. Luce, M. Suárez-Durán, Maximilian Reininghaus, A. Zepeda, Brian Fick, Nicolás González, P. Stassi, Ladislav Chytka, Lino Miramonti, Ioana Codrina Maris, Pedro Assis, François Montanet, Radomir Smida, A. Machado Payeras, Martin Erdmann, J. de Jesús, H. Martinez, A. Etchegoyen, Maximilian Stadelmaier, Sullivan Marafico, Miguel Mostafa, P. Ruehl, D. de Oliveira Franco, A. Streich, Gioacchino Alex Anastasi, Dusan Mandat, J. Stasielak, J. Hulsman, J. Kleinfeller, G. C. Hill, Marco Giammarchi, M. Wirtz, Frank G. Schröder, Eleonora Guido, Roger W Clay, Jorge F. Soriano, Ralph Engel, Denis Stanca, C. M. Schäfer, Fernando Gollan, Massimo Mastrodicasa, Hernan Wahlberg, L. Nellen, Carlos Escobar, Kevin-Druis Merenda, Samo Stanič, K. H. Kampert, J. Ridky, R.J. Barreira Luz, Martin Vacula, John Farmer, C. Morello, Heino Falcke, A. Puyleart, V. de Souza, R. Conceição, Miroslav Hrabovský, Corinne Berat, M. Giller, Isabel Goos, Luis A. Anchordoqui, A. Parra, J. Perez Armand, Kai Daumiller, D. Heck, Maria-Teresa Dova, M. R. Hampel, J. Vicha, A. Haungs, L. Bonneau Arbeletche, Peter L. Biermann, Philipp Papenbreer, M. Schimassek, M. del Río, C. Hojvat, Petr Travnicek, Jan Ebr, Claudio Galelli, Denise Boncioli, Trent D. Grubb, Paolo Privitera, P. Ristori, Jacco Vink, M. Trini, H.O. Klages, M. A. Muller, Markus Roth, Juan Manuel Figueira, Roberta Colalillo, A. G. Mariazzi, P. Savina, A. Aab, A. A. Nucita, Ralf Ulrich, Martina Bohacova, M. I. Micheletti, B. L. Lago, R.C. dos Anjos, Adriana Vásquez-Ramírez, Giovanni Mancarella, Juan Pablo Gongora, M. Palatka, P. Mantsch, A. Cancio, Z. Szadkowski, Matias Tueros, Luis A. Nunez, Paula Gina Isar, F. Salamida, V. Novotny, I. Allekotte, M. J. Roncoroni, Rossella Caruso, A. Lucero, Fernando Catalani, T. Suomijärvi, Caterina Trimarelli, A. Yushkov, D. Melo, D. Nosek, E. Santos, R. Sato, J. Pallotta, A. M. Botti, Niraj Dhital, I. Valiño, G. P. Guedes, Alessio Gorgi, A. Weindl, L. Nožka, Toshihiro Fujii, Orazio Zapparrata, Jakub Juryšek, J. Debatin, Carola Dobrigkeit, M. Muzio, Steffen Hahn, Juan Carlos D'Olivo, T. Pierog, Esteban Roulet, Justin M. Albury, Alan Watson, David Schmidt, S. Schröder, Italo Epicoco, M. Perlin, Mihai Niculescu-Oglinzanu, Piera Luisa Ghia, G. Farrar, A. Taboada, P.F. Gómez Vitale, Violet M. Harvey, D. Harari, Alina Mihaela Badescu, Cristina Galea, M. Prouza, Gaia Silli, A. Filipčič, S. Petrera, Marc Weber, Bjarni Pont, C. J.W.P. Timmermans, K. Choi, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Pierre Auger, Aab, A, Abreu, P, Aglietta, M, Albury, J M, Allekotte, I, Almela, A, Alvarez-Muñiz, J, Alves Batista, R, Anastasi, G A, Anchordoqui, L, Andrada, B, Andringa, S, Aramo, C, Araújo Ferreira, P R, Asorey, H, Assis, P, Avila, G, Badescu, A M, Bakalova, A, Balaceanu, A, Barbato, F, Barreira Luz, R J, Becker, K H, Bellido, J A, Berat, C, Bertaina, M E, Bertou, X, Biermann, P L, Bister, T, Biteau, J, Blazek, J, Bleve, C, Boháčová, M, Boncioli, D, Bonifazi, C, Bonneau Arbeletche, L, Borodai, N, Botti, A M, Brack, J, Bretz, T, Briechle, F L, Buchholz, P, Bueno, A, Buitink, S, Buscemi, M, Caballero-Mora, K S, Caccianiga, L, Cancio, A, Canfora, F, Caracas, I, Carceller, J M, Caruso, R, Castellina, A, Catalani, F, Cataldi, G, Cazon, L, Cerda, M, Chinellato, J A, Choi, K, Chudoba, J, Chytka, L, Clay, R W, Cobos Cerutti, A C, Colalillo, R, Coleman, A, Coluccia, M R, Conceição, R, Condorelli, A, Consolati, G, Contreras, F, Convenga, F, Covault, C E, Dasso, S, Daumiller, K, Dawson, B R, Day, J A, de Almeida, R M, de Jesús, J, de Jong, S J, De Mauro, G, de Mello Neto, J R T, De Mitri, I, de Oliveira, J, de Oliveira Franco, D, de Souza, V, De Vito, E, Debatin, J, Del Río, M, Deligny, O, Dembinski, H, Dhital, N, Di Matteo, A, Dobrigkeit, C, D'Olivo, J C, Dos Anjos, R C, Dova, M T, Ebr, J, Engel, R, Epicoco, I, Erdmann, M, Escobar, C O, Etchegoyen, A, Falcke, H, Farmer, J, Farrar, G, Fauth, A C, Fazzini, N, Feldbusch, F, Fenu, F, Fick, B, Figueira, J M, Filipčič, A, Fodran, T, Freire, M M, Fujii, T, Fuster, A, Galea, C, Galelli, C, García, B, Garcia Vegas, A L, Gemmeke, H, Gesualdi, F, Gherghel-Lascu, A, Ghia, P L, Giaccari, U, Giammarchi, M, Giller, M, Glombitza, J, Gobbi, F, Gollan, F, Golup, G, Gómez Berisso, M, Gómez Vitale, P F, Gongora, J P, González, N, Goos, I, Góra, D, Gorgi, A, Gottowik, M, Grubb, T D, Guarino, F, Guedes, G P, Guido, E, Hahn, S, Halliday, R, Hampel, M R, Hansen, P, Harari, D, Harvey, V M, Haungs, A, Hebbeker, T, Heck, D, Hill, G C, Hojvat, C, Hörandel, J R, Horvath, P, Hrabovský, M, Huege, T, Hulsman, J, Insolia, A, Isar, P G, Johnsen, J A, Jurysek, J, Kääpä, A, Kampert, K H, Keilhauer, B, Kemp, J, Klages, H O, Kleifges, M, Kleinfeller, J, Köpke, M, Kukec Mezek, G, Lago, B L, Lahurd, D, Lang, R G, Langner, N, Leigui de Oliveira, M A, Lenok, V, Letessier-Selvon, A, Lhenry-Yvon, I, Lo Presti, D, Lopes, L, López, R, Lorek, R, Luce, Q, Lucero, A, Lundquist, J P, Machado Payeras, A, Mancarella, G, Mandat, D, Manning, B C, Manshanden, J, Mantsch, P, Marafico, S, Mariazzi, A G, Mariş, I C, Marsella, G, Martello, D, Martinez, H, Martínez Bravo, O, Mastrodicasa, M, Mathes, H J, Matthews, J, Matthiae, G, Mayotte, E, Mazur, P O, Medina-Tanco, G, Melo, D, Menshikov, A, Merenda, K-D, Michal, S, Micheletti, M I, Miramonti, L, Mollerach, S, Montanet, F, Morello, C, Mostafá, M, Müller, A L, Muller, M A, Mulrey, K, Mussa, R, Muzio, M, Namasaka, W M, Nellen, L, Niculescu-Oglinzanu, M, Niechciol, M, Nitz, D, Nosek, D, Novotny, V, Nožka, L, Nucita, A, Núñez, L A, Palatka, M, Pallotta, J, Papenbreer, P, Parente, G, Parra, A, Pech, M, Pedreira, F, Pȩkala, J, Pelayo, R, Peña-Rodriguez, J, Perez Armand, J, Perlin, M, Perrone, L, Petrera, S, Pierog, T, Pimenta, M, Pirronello, V, Platino, M, Pont, B, Pothast, M, Privitera, P, Prouza, M, Puyleart, A, Querchfeld, S, Rautenberg, J, Ravignani, D, Reininghaus, M, Ridky, J, Riehn, F, Risse, M, Ristori, P, Rizi, V, Rodrigues de Carvalho, W, Rodriguez Rojo, J, Roncoroni, M J, Roth, M, Roulet, E, Rovero, A C, Ruehl, P, Saffi, S J, Saftoiu, A, Salamida, F, Salazar, H, Salina, G, Sanabria Gomez, J D, Sánchez, F, Santos, E M, Santos, E, Sarazin, F, Sarmento, R, Sarmiento-Cano, C, Sato, R, Savina, P, Schäfer, C M, Scherini, V, Schieler, H, Schimassek, M, Schimp, M, Schlüter, F, Schmidt, D, Scholten, O, Schovánek, P, Schröder, F G, Schröder, S, Schulte, J, Sciutto, S J, Scornavacche, M, Shellard, R C, Sigl, G, Silli, G, Sima, O, Šmída, R, Sommers, P, Soriano, J F, Souchard, J, Squartini, R, Stadelmaier, M, Stanca, D, Stanič, S, Stasielak, J, Stassi, P, Streich, A, Suárez-Durán, M, Sudholz, T, Suomijärvi, T, Supanitsky, A D, Šupík, J, Szadkowski, Z, Taboada, A, Tapia, A, Timmermans, C, Tkachenko, O, Tobiska, P, Todero Peixoto, C J, Tomé, B, Torralba Elipe, G, Travaini, A, Travnicek, P, Trimarelli, C, Trini, M, Tueros, M, Ulrich, R, Unger, M, Vaclavek, L, Vacula, M, Valdés Galicia, J F, Valiño, I, Valore, L, Varela, E, Varma K C, V, Vásquez-Ramírez, A, Veberič, D, Ventura, C, Vergara Quispe, I D, Verzi, V, Vicha, J, Vink, J, Vorobiov, S, Wahlberg, H, Watson, A A, Weber, M, Weindl, A, Wiencke, L, Wilczyński, H, Winchen, T, Wirtz, M, Wittkowski, D, Wundheiler, B, Yushkov, A, Zapparrata, O, Zas, E, Zavrtanik, D, Zavrtanik, M, Zehrer, L, Zepeda, A, High Energy Astrophys. & Astropart. Phys (API, FNWI), Gravitation and Astroparticle Physics Amsterdam, Physics, Aab, A., Abreu, P., Aglietta, M., Albury, J. M., Allekotte, I., Almela, A., Alvarez-Muniz, J., Alves Batista, R., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Araujo Ferreira, P. R., Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Barreira Luz, R. J., Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Bister, T., Biteau, J., Blazek, J., Bleve, C., Bohacova, M., Boncioli, D., Bonifazi, C., Bonneau Arbeletche, L., Borodai, N., Botti, A. M., Brack, J., Bretz, T., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero-Mora, K. S., Caccianiga, L., Cancio, A., Canfora, F., Caracas, I., Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Choi, K., Chudoba, J., Chytka, L., Clay, R. W., Cobos Cerutti, A. C., Colalillo, R., Coleman, A., Coluccia, M. R., Conceicao, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., Covault, C. E., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., De Almeida, R. M., De Jesus, J., De Jong, S. J., De Mauro, G., De Mello Neto, J. R. T., De Mitri, I., De Oliveira, J., De Oliveira Franco, D., De Souza, V., De Vito, E., Debatin, J., Del Rio, M., Deligny, O., Dembinski, H., Dhital, N., Di Matteo, A., Dobrigkeit, C., D'Olivo, J. C., Dos Anjos, R. C., Dova, M. T., Ebr, J., Engel, R., Epicoco, I., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fick, B., Figueira, J. M., Filipcic, A., Fodran, T., Freire, M. M., Fujii, T., Fuster, A., Galea, C., Galelli, C., Garcia, B., Garcia Vegas, A. L., Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Giller, M., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Gomez Berisso, M., Gomez Vitale, P. F., Gongora, J. P., Gonzalez, N., Goos, I., Gora, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Hahn, S., Halliday, R., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Hill, G. C., Hojvat, C., Horandel, J. R., Horvath, P., Hrabovsky, M., Huege, T., Hulsman, J., Insolia, A., Isar, P. G., Johnsen, J. A., Jurysek, J., Kaapa, A., Kampert, K. H., Keilhauer, B., Kemp, J., Klages, H. O., Kleifges, M., Kleinfeller, J., Kopke, M., Kukec Mezek, G., Lago, B. L., Lahurd, D., Lang, R. G., Langner, N., Leigui De Oliveira, M. A., Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Lo Presti, D., Lopes, L., Lopez, R., Lorek, R., Luce, Q., Lucero, A., Lundquist, J. P., Machado Payeras, A., Mancarella, G., Mandat, D., Manning, B. C., Manshanden, J., Mantsch, P., Marafico, S., Mariazzi, A. G., Maris, I. C., Marsella, G., Martello, D., Martinez, H., Martinez Bravo, O., Mastrodicasa, M., Mathes, H. J., Matthews, J., Matthiae, G., Mayotte, E., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Merenda, K. -D., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morello, C., Mostafa, M., Muller, A. L., Muller, M. A., Mulrey, K., Mussa, R., Muzio, M., Namasaka, W. M., Nellen, L., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nozka, L., Nucita, A., Nunez, L. A., Palatka, M., Pallotta, J., Papenbreer, P., Parente, G., Parra, A., Pech, M., Pedreira, F., Pkala, J., Pelayo, R., Pena-Rodriguez, J., Perez Armand, J., Perlin, M., Perrone, L., Petrera, S., Pierog, T., Pimenta, M., Pirronello, V., Platino, M., Pont, B., Pothast, M., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Ristori, P., Rizi, V., Rodrigues De Carvalho, W., Rodriguez Rojo, J., Roncoroni, M. J., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saffi, S. J., Saftoiu, A., Salamida, F., Salazar, H., Salina, G., Sanabria Gomez, J. D., Sanchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sarmiento-Cano, C., Sato, R., Savina, P., Schafer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schluter, F., Schmidt, D., Scholten, O., Schovanek, P., Schroder, F. G., Schroder, S., Schulte, J., Sciutto, S. J., Scornavacche, M., Shellard, R. C., Sigl, G., Silli, G., Sima, O., Smida, R., Sommers, P., Soriano, J. F., Souchard, J., Squartini, R., Stadelmaier, M., Stanca, D., Stanic, S., Stasielak, J., Stassi, P., Streich, A., Suarez-Duran, M., Sudholz, T., Suomijarvi, T., Supanitsky, A. D., Supik, J., Szadkowski, Z., Taboada, A., Tapia, A., Timmermans, C., Tkachenko, O., Tobiska, P., Todero Peixoto, C. J., Tome, B., Torralba Elipe, G., Travaini, A., Travnicek, P., Trimarelli, C., Trini, M., Tueros, M., Ulrich, R., Unger, M., Vaclavek, L., Vacula, M., Valdes Galicia, J. F., Valino, I., Valore, L., Varela, E., Varma, K. C. V., Vasquez-Ramirez, A., Veberic, D., Ventura, C., Vergara Quispe, I. D., Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Wahlberg, H., Watson, A. A., Weber, M., Weindl, A., Wiencke, L., Wilczynski, H., Winchen, T., Wirtz, M., Wittkowski, D., Wundheiler, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., Zehrer, L., Zepeda, A., Astronomy, Aab A., Abreu P., Aglietta M., Albury J.M., Allekotte I., Almela A., Alvarez-Muniz J., Alves Batista R., Anastasi G.A., Anchordoqui L., Andrada B., Andringa S., Aramo C., Araujo Ferreira P.R., Asorey H., Assis P., Avila G., Badescu A.M., Bakalova A., Balaceanu A., Barbato F., Barreira Luz R.J., Becker K.H., Bellido J.A., Berat C., Bertaina M.E., Bertou X., Biermann P.L., Bister T., Biteau J., Blazek J., Bleve C., Bohacova M., Boncioli D., Bonifazi C., Bonneau Arbeletche L., Borodai N., Botti A.M., Brack J., Bretz T., Briechle F.L., Buchholz P., Bueno A., Buitink S., Buscemi M., Caballero-Mora K.S., Caccianiga L., Cancio A., Canfora F., Caracas I., Carceller J.M., Caruso R., Castellina A., Catalani F., Cataldi G., Cazon L., Cerda M., Chinellato J.A., Choi K., Chudoba J., Chytka L., Clay R.W., Cobos Cerutti A.C., Colalillo R., Coleman A., Coluccia M.R., Conceicao R., Condorelli A., Consolati G., Contreras F., Convenga F., Covault C.E., Dasso S., Daumiller K., Dawson B.R., Day J.A., De Almeida R.M., De Jesus J., De Jong S.J., De Mauro G., De Mello Neto J.R.T., De Mitri I., De Oliveira J., De Oliveira Franco D., De Souza V., De Vito E., Debatin J., Del Rio M., Deligny O., Dembinski H., Dhital N., Di Matteo A., Dobrigkeit C., D'Olivo J.C., Dos Anjos R.C., Dova M.T., Ebr J., Engel R., Epicoco I., Erdmann M., Escobar C.O., Etchegoyen A., Falcke H., Farmer J., Farrar G., Fauth A.C., Fazzini N., Feldbusch F., Fenu F., Fick B., Figueira J.M., Filipcic A., Fodran T., Freire M.M., Fujii T., Fuster A., Galea C., Galelli C., Garcia B., Garcia Vegas A.L., Gemmeke H., Gesualdi F., Gherghel-Lascu A., Ghia P.L., Giaccari U., Giammarchi M., Giller M., Glombitza J., Gobbi F., Gollan F., Golup G., Gomez Berisso M., Gomez Vitale P.F., Gongora J.P., Gonzalez N., Goos I., Gora D., Gorgi A., Gottowik M., Grubb T.D., Guarino F., Guedes G.P., Guido E., Hahn S., Halliday R., Hampel M.R., Hansen P., Harari D., Harvey V.M., Haungs A., Hebbeker T., Heck D., Hill G.C., Hojvat C., Horandel J.R., Horvath P., Hrabovsky M., Huege T., Hulsman J., Insolia A., Isar P.G., Johnsen J.A., Jurysek J., Kaapa A., Kampert K.H., Keilhauer B., Kemp J., Klages H.O., Kleifges M., Kleinfeller J., Kopke M., Kukec Mezek G., Lago B.L., Lahurd D., Lang R.G., Langner N., Leigui De Oliveira M.A., Lenok V., Letessier-Selvon A., Lhenry-Yvon I., Lo Presti D., Lopes L., Lopez R., Lorek R., Luce Q., Lucero A., Lundquist J.P., Machado Payeras A., Mancarella G., Mandat D., Manning B.C., Manshanden J., Mantsch P., Marafico S., Mariazzi A.G., Maris I.C., Marsella G., Martello D., Martinez H., Martinez Bravo O., Mastrodicasa M., Mathes H.J., Matthews J., Matthiae G., Mayotte E., Mazur P.O., Medina-Tanco G., Melo D., Menshikov A., Merenda K.-D., Michal S., Micheletti M.I., Miramonti L., Mollerach S., Montanet F., Morello C., Mostafa M., Muller A.L., Muller M.A., Mulrey K., Mussa R., Muzio M., Namasaka W.M., Nellen L., Niculescu-Oglinzanu M., Niechciol M., Nitz D., Nosek D., Novotny V., NoZka L., Nucita A., Nunez L.A., Palatka M., Pallotta J., Papenbreer P., Parente G., Parra A., Pech M., Pedreira F., Pkala J., Pelayo R., Pena-Rodriguez J., Perez Armand J., Perlin M., Perrone L., Petrera S., Pierog T., Pimenta M., Pirronello V., Platino M., Pont B., Pothast M., Privitera P., Prouza M., Puyleart A., Querchfeld S., Rautenberg J., Ravignani D., Reininghaus M., Ridky J., Riehn F., Risse M., Ristori P., Rizi V., Rodrigues De Carvalho W., Rodriguez Rojo J., Roncoroni M.J., Roth M., Roulet E., Rovero A.C., Ruehl P., Saffi S.J., Saftoiu A., Salamida F., Salazar H., Salina G., Sanabria Gomez J.D., Sanchez F., Santos E.M., Santos E., Sarazin F., Sarmento R., Sarmiento-Cano C., Sato R., Savina P., Schafer C.M., Scherini V., Schieler H., Schimassek M., Schimp M., Schluter F., Schmidt D., Scholten O., Schovanek P., Schroder F.G., Schroder S., Schulte J., Sciutto S.J., Scornavacche M., Shellard R.C., Sigl G., Silli G., Sima O., Smida R., Sommers P., Soriano J.F., Souchard J., Squartini R., Stadelmaier M., Stanca D., Stanic S., Stasielak J., Stassi P., Streich A., Suarez-Duran M., Sudholz T., Suomijarvi T., Supanitsky A.D., Supik J., Szadkowski Z., Taboada A., Tapia A., Timmermans C., Tkachenko O., Tobiska P., Todero Peixoto C.J., Tome B., Torralba Elipe G., Travaini A., Travnicek P., Trimarelli C., Trini M., Tueros M., Ulrich R., Unger M., Vaclavek L., Vacula M., Valdes Galicia J.F., Valino I., Valore L., Varela E., Varma K. C. V., Vasquez-Ramirez A., Veberic D., Ventura C., Vergara Quispe I.D., Verzi V., Vicha J., Vink J., Vorobiov S., Wahlberg H., Watson A.A., Weber M., Weindl A., Wiencke L., Wilczynski H., Winchen T., Wirtz M., Wittkowski D., Wundheiler B., Yushkov A., Zapparrata O., Zas E., Zavrtanik D., Zavrtanik M., Zehrer L., and Zepeda A.

Subjects
interaction: model, Physics::Instrumentation and Detectors, Astronomy, Hadron, General Physics and Astronomy, Ultra-high energy cosmic rays, muons properties, hadronic models, 01 natural sciences, cosmic ray, particle interaction, astroparticle detectors, Auger, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), iron, surface [detector], Observatory, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Physics, 4. Education, Settore FIS/01 - Fisica Sperimentale, measured [fluctuation], model [interaction], Astrophysics::Instrumentation and Methods for Astrophysics, model: hadronic, fluctuation: measured, 3. Good health, observatory, Sciences exactes et naturelles, atmosphere [showers], model [particle], air, Cherenkov counter: water, Astrophysics::High Energy Astrophysical Phenomena, UHE [cosmic radiation], FOS: Physical sciences, Cosmic ray, detector: fluorescence, Nuclear physics, cosmic rays, muon, 0103 physical sciences, calorimeter, ddc:530, 14. Life underwater, cosmic radiation: UHE, High Energy Physics, distribution function, electromagnetic component, 010306 general physics, Astrophysique, Pierre Auger Observatory, fluorescence [detector], Muon, showers: atmosphere, hep-ex, detector: surface, water [Cherenkov counter], particle: model, Small deviations, Física, ASTROFÍSICA, Air shower, Experimental High Energy Physics, Elementary Particles and Fields, hadronic [model], High Energy Physics::Experiment
Abstract

The successful installation, commissioning, and operation of the Pierre Auger Observatory would not have been possible without the strong commitment and effort from the technical and administrative staff in Malargue. We are very grateful to the following agencies and organizations for financial support: Argentina-Comision Nacional de Energia Atomica, Agencia Nacional de Promocion Cientifica y Tecnologica (ANPCyT), Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Gobierno de la Provincia de Mendoza, Municipalidad de Malargue, NDM Holdings and Valle Las Lenas; in gratitude for their continuing cooperation over land access; Australia-the Australian Research Council; BrazilConselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq), Financiadora de Estudos e Projetos (FINEP), Fundacao de Amparo a Pesquisa do Estado de Rio de Janeiro (FAPERJ), Sao Paulo Research Foundation (FAPESP) Grants No. 2019/10151-2, No. 2010/07359-6, and No. 1999/05404-3, Ministerio da Ciencia, Tecnologia, Inovacoes e Comunicacoes (MCTIC); Ministry of Education, Youth and Sports of the Czech RepublicGrants No. MSMT CR LTT18004, No. LM2015038, No. LM2018102, No. CZ.02.1.01/0.0/0.0/16_013/0001402, No. CZ.02.1.01/0.0/0.0/18_046/0016010, and No. CZ.02.1.01/0.0/0.0/17_049/0008422; France-Centre de Calcul IN2P3/CNRS, Centre National de la Recherche Scientifique (CNRS), Conseil Regional Ile-de-France, Departement Physique Nucl ' eaire et Corpusculaire (PNC-IN2P3/CNRS), Departement Sciences de l'Univers (SDU-INSU/CNRS), Institut Lagrange de Paris (ILP) Grant No. LABEX ANR-10-LABX-63 within the Investissements d'Avenir Programme Grant No. ANR11-IDEX-0004-02; Germany-Bundesministerium fur Bildung und Forschung (BMBF), Deutsche Forschungsgemeinschaft (DFG), Finanzministerium Baden-Wurttemberg, Helmholtz Alliance for Astroparticle Physics (HAP), Helmholtz-Gemeinschaft Deutscher Forschungszentren (HGF), Ministerium fur Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen, Ministerium fur Wissenschaft, Forschung und Kunst des Landes Baden-Wurttemberg; Italy-Istituto Nazionale di Fisica Nucleare (INFN), Istituto Nazionale di Astrofisica (INAF), Ministero dell'Istruzione, dell'Universita e della Ricerca (MIUR), CETEMPS Center of Excellence, Ministero degli Affari Esteri (MAE); Mexico-Consejo Nacional de Ciencia y Tecnologia (CONACYT) Grant No. 167733, Universidad Nacional Autonoma de Mexico (UNAM), PAPIIT DGAPA-UNAM; The Netherlands-Ministry of Education, Culture and Science, Netherlands Organisation for Scientific Research (NWO), Dutch national e-infrastructure with the support of SURF Cooperative; Poland-Ministry of Science and Higher Education, Grant No. DIR/WK/2018/11, National Science Centre, Grants No. 2013/08/M/ST9/00322, No. 2016/23/B/ST9/01635, and No. HARMONIA 5-2013/10/M/ST9/00062, UMO-2016/22/M/ST9/00198; Portugal -Portuguese national funds and FEDER funds within Programa Operacional Factores de Competitividade through Fundacao para a Ciencia e a Tecnologia (COMPETE); Romania-Romanian Ministry of Education and Research, the Program Nucleu within MCI (PN19150201/16N/2019 and PN19060102), and project PN-III-P1-1.2-PCCDI-2017-0839/19PCCDI/2018 within PNCDI III; Slovenia-Slovenian Research Agency, Grants No. P1-0031, No. P1-0385, No. I00033, No. N1-0111; Spain-Ministerio de Economia, Industria y Competitividad (FPA2017-85114-P and FPA2017-85197-P), Xunta de Galicia (ED431C 2017/07), Junta de Andalucia (SOMM17/6104/UGR), Feder Funds, RENATA Red Nacional Tematica de Astroparticulas (FPA2015-68783-REDT), and Maria de Maeztu Unit of Excellence (MDM-2016-0692); U.S.Department of Energy, Awards No. DE-AC0207CH11359, No. DE-FR02-04ER41300, No. DE-FG0299ER41107, and No. DE-SC0011689, National Science Foundation, Grant No. 0450696, The Grainger Foundation, Marie Curie-IRSES/EPLANET, European Particle Physics Latin American Network, and UNESCO., We present the first measurement of the fluctuations in the number of muons in extensive air showers produced by ultrahigh energy cosmic rays. We find that the measured fluctuations are in good agreement with predictions from air shower simulations. This observation provides new insights into the origin of the previously reported deficit of muons in air shower simulations and constrains models of hadronic interactions at ultrahigh energies. Our measurement is compatible with the muon deficit originating from small deviations in the predictions from hadronic interaction models of particle production that accumulate as the showers develop., Argentina-Comision Nacional de Energia Atomica, ANPCyT, Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Gobierno de la Provincia de Mendoza, Municipalidad de Malargue, NDM Holdings, Valle Las Lenas, Australian Research Council, Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ), Fundacao de Apoio a Pesquisa do Distrito Federal (FAPDF), Financiadora de Inovacao e Pesquisa (Finep), Fundacao Carlos Chagas Filho de Amparo a Pesquisa do Estado do Rio De Janeiro (FAPERJ), Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) 2019/10151-2 2010/07359-6 1999/05404-3, Ministerio da Ciencia, Tecnologia, Inovacoes e Comunicacoes (MCTIC), Ministry of Education, Youth & Sports - Czech Republic MSMT CR LTT18004 LM2015038 LM2018102 CZ.02.1.01/0.0/0.0/16_013/0001402 CZ.02.1.01/0.0/0.0/18_046/0016010 CZ.02.1.01/0.0/0.0/17_049/0008422, France-Centre de Calcul IN2P3/CNRS, Centre National de la Recherche Scientifique (CNRS), Region Ile-de-France, Departement Sciences de l'Univers (SDU-INSU/CNRS), French National Research Agency (ANR) LABEX ANR-10-LABX-63 ANR11-IDEX-0004-02, Federal Ministry of Education & Research (BMBF), German Research Foundation (DFG), Finanzministerium Baden-Wurttemberg, Helmholtz Alliance for Astroparticle Physics (HAP), Helmholtz Association, Ministerium fur Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen, Ministerium fur Wissenschaft, Forschung und Kunst des Landes Baden-Wurttemberg, Italy-Istituto Nazionale di Fisica Nucleare (INFN), Istituto Nazionale Astrofisica (INAF), Ministry of Education, Universities and Research (MIUR), CETEMPS Center of Excellence, Ministry of Foreign Affairs and International Cooperation (Italy), Consejo Nacional de Ciencia y Tecnologia (CONACyT) 167733, Universidad Nacional Autonoma de Mexico (UNAM), PAPIIT DGAPA-UNAM, Netherlands-Ministry of Education, Culture and Science, Netherlands Organization for Scientific Research (NWO), Dutch national e-infrastructure, SURF Cooperative, Poland-Ministry of Science and Higher Education DIR/WK/2018/11, National Science Centre, Poland 2013/08/M/ST9/00322 2016/23/B/ST9/01635 HARMONIA 5-2013/10/M/ST9/00062 UMO-2016/22/M/ST9/00198, Portugal -Portuguese national funds, FEDER funds within Programa Operacional Factores de Competitividade through Fundacao para a Ciencia e a Tecnologia (COMPETE), Romania-Romanian Ministry of Education and Research, the Program Nucleu within MCI PN19150201/16N/2019 PN19060102, Romania-Romanian Ministry of Educatio n and Research, the Program Nucleu within PNCDI III PN-III-P1-1.2-PCCDI-2017-0839/19PCCDI/2018, Slovenian Research Agency - Slovenia P1-0031 P1-0385 I00033 N1-0111, Spain-Ministerio de Economia, Industria y Competitividad FPA2017-85114-P FPA2017-85197-P, Xunta de Galicia European Commission ED431C 2017/07, Junta de Andalucia SOMM17/6104/UGR, European Commission, RENATA Red Nacional Tematica de Astroparticulas FPA2015-68783-REDT, Maria de Maeztu Unit of Excellence MDM-2016-0692, United States Department of Energy (DOE) DE-AC0207CH11359 DE-FR02-04ER41300 DE-FG0299ER41107 DE-SC0011689, National Science Foundation (NSF) 0450696, Grainger Foundation, Marie Curie-IRSES/EPLANET, European Particle Physics Latin American Network, UNESCO

Published
2021
Full Text
View/download PDF

46. Analytical warm dark matter power spectrum on small scales

Author

L. G. Medeiros, G. Pordeus-da-Silva, and R. C. Batista

Subjects
Physics, Cosmology and Nongalactic Astrophysics (astro-ph.CO), Equation of state (cosmology), Matter power spectrum, Dark matter, Spectral density, FOS: Physical sciences, Astronomy and Astrophysics, Perfect fluid, Astrophysics::Cosmology and Extragalactic Astrophysics, Redshift, Computational physics, Warm dark matter, Dark energy, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

Using the Reduced Relativistic Gas (RRG) model, we analytically determine the matter power spectrum for Warm Dark Matter (WDM) on small scales, $k>1\ h\text{/Mpc}$. The RRG is a simplified model for the ideal relativistic gas, but very accurate in the cosmological context. In another work, we have shown that, for typical allowed masses for dark matter particles, $m>5\ \text{keV}$, the higher order multipoles, $\ell>2$, in the Einstein-Boltzmann system of equations are negligible on scales $k, 23 pages, 9 figures, matches the accepted version in JCAP

Published
2021
Full Text
View/download PDF

47. A step forward in the detection of byproducts of anthropogenic organic micropollutants in chlorinated water

Author

Postigo, C. Gil-Solsona, R. Herrera-Batista, M.F. Gago-Ferrero, P. Alygizakis, N. Ahrens, L. Wiberg, K.

Subjects
cardiovascular system
Abstract

Contaminants of emerging concern (CECs) are widespread in the water cycle. Their levels in disinfected waters are usually low, as they may transform into CEC disinfection byproducts (DBPs) during disinfection processes or partially removed in previous water treatment steps. The occurrence of CEC DBPs in real waters has been scarcely addressed, although their presence may be of relevance in water circular economy scenarios, and thus deserves further study in water regeneration systems. In this work, a database of CEC DBPs (n=1338) after chlorination was generated and is ready to use in future screening studies to assess the relevance of these chemicals in contaminat mixtures. Moreover, the transformation of CECs during chlorination, their main reaction pathways with chlorine, and current knowledge gaps were critically reviewed. © 2021 The Author(s)

Published
2021

48. PPARα Gene Is Involved in Body Composition Variation in Response to an Aerobic Training Program in Overweight/Obese

Author

Joane R. E. Batista, João Modesto Filho, Yohanna de Oliveira, Klécia de Farias Sena, Bruno R. V. Sousa, Mateus Duarte Ribeiro, Alexandre Sérgio Silva, Antonio Eduardo Monteiro de Almeida, Darlene Camati Persuhn, Glêbia Alexa Cardoso, and Raquel S Brito Silva

Subjects
medicine.medical_specialty, education.field_of_study, Waist, Article Subject, business.industry, QH301-705.5, Population, Overweight, Endocrinology, Internal medicine, Drug Discovery, Genotype, medicine, Aerobic exercise, Pharmacology (medical), Analysis of variance, medicine.symptom, Biology (General), education, business, Body mass index, Aerobic capacity
Abstract

The objective of this study was to investigate the relationship of the polymorphism in Intron 7 G/C (rs 4253778) of the peroxisome proliferator-activated receptor alpha (PPARα) gene with the magnitude of changes in the body composition of an overweight and obese population that underwent an aerobic training program. Fifty-eight previously inactive men and women, body mass index (BMI) 31.5 ± 2.8 kg / m 2 , 46.5% ( n = 27 ) genotyped as CC genotype and 53.5% ( n = 31 ) as CA+AA, underwent a 12-week aerobic training (walking/running). Aerobic capacity (ergospirometry), body composition (DXA), and nutritional assessment were made before and 48 h after the experimental protocol. Two-way ANOVA, chi-square test, and logistic regression were used ( p < 0.05 ). Twenty-seven volunteers (46.5%) were identified as CC genotype and 31 (53.5%) as CA+AA genotype. Time-group interaction showed that there was no difference in these between two allele groups. However, differences in distribution of respondents or nonresponders according to allele A were identified for fat mass ( p ≤ 0.003 ), percentage fat mass ( p ≤ 0.002 ), the waist ( p ≤ 0.009 ), abdomen ( p ≤ 0.000 ), and hip ( p ≤ 0.001 ), this difference being independent for the fat mass. Meanwhile, sex, age, and nutritional management have also been found to be influential factors. It is concluded that the PPARα gene is involved in varying body composition in response to an aerobic training program.

Published
2021

49. Design, upgrade and characterization of the silicon photomultiplier front-end for the AMIGA detector at the Pierre Auger Observatory

Author

Silvia Mollerach, N. Fazzini, Jonas Glombitza, F. C. T. Barbato, D. Zavrtanik, Serguei Vorobiov, J. Kleinfeller, Marcos Cerda, Denis Stanca, D. Melo, W. M. Namasaka, L. Lopes, A. C. Rovero, Alexandru Balaceanu, Carla Aramo, Julien Souchard, D. Martello, O. Martínez Bravo, K. Mulrey, Carla Bleve, Rodrigo Guedes Lang, Jaime Alvarez-Muñiz, Kevin-Druis Merenda, Alexandru Gherghel-Lascu, E. Santos, Thomas Bretz, Tiina Suomijarvi, V. Rizi, Corbin Covault, Vladimir Lenok, J. Stasielak, P. Tobiska, L. Perrone, L. Valore, R. Sato, Lino Miramonti, D. de Oliveira Franco, Lukáš Vaclavek, G. Mancarella, G. Marsella, A. Weindl, P. Savina, W. Rodrigues de Carvalho, Teresa Bister, Dalibor Nosek, M. Schimp, B. C. Manning, G. P. Guedes, Bjarni Pont, Luis A. Anchordoqui, A. Di Matteo, Marvin Gottowik, B. Keilhauer, P. Abreu, D. Ravignani, Alessio Gorgi, Maximilian Reininghaus, Flavia Gesualdi, Dusan Mandat, Sullivan Marafico, M. Risse, Orazio Zapparrata, Francesco Fenu, Ralf Ulrich, B. Wundheiler, Paul Sommers, Patricia María Hansen, Philipp Papenbreer, E. M. Santos, Eric Mayotte, Toshihiro Fujii, S. J. Sciutto, Juan Miguel Carceller, David Schmidt, J. Perez Armand, M. Gómez Berisso, S. Schröder, Italo Epicoco, Kai Daumiller, F. Sánchez, Marco Giammarchi, Nataliia Borodai, Christian Sarmiento-Cano, G. Parente, Fabrizia Canfora, K. Choi, L. Zehrer, Miroslav Pech, M. Pothast, Valerio Pirronello, C. J.W.P. Timmermans, C. M. Schäfer, C. J. Todero Peixoto, J. F. Valdés Galicia, I. De Mitri, Denise Boncioli, Jakub Juryšek, J. Debatin, Antonio Condorelli, Carola Dobrigkeit, M. Muzio, J. de Oliveira, Martin Vacula, Marcel Köpke, M. Platino, R. Alves Batista, Bruce R. Dawson, Trent D. Grubb, D. Nitz, Alejandro Almela, P. Horvath, J. Chudoba, P.O. Mazur, Darko Veberič, Julian Kemp, B. Andrada, A.L. Garcia Vegas, Sofia Andringa, M. A. Muller, A. Aab, G. Cataldi, Michael Prouza, Fred Sarazin, F. Riehn, T. Huege, Marina Scornavacche, A. Tapia, B. Tome, Josina Schulte, Alex Kääpä, Martina Bohacova, L. Nožka, G. De Mauro, F. Guarino, John Matthews, Peter Buchholz, Steffen Hahn, Claudio Galelli, Juan Carlos D'Olivo, T. Pierog, Juan Manuel Figueira, Mario Buscemi, L. R. Wiencke, Niklas Langner, Roberta Colalillo, Heino Falcke, V. Scherini, Maria Rita Coluccia, Jeffrey Brack, Olaf Scholten, Octavian Sima, Marco Aglietta, Marko Zavrtanik, H. Schieler, Esteban Roulet, A. G. Mariazzi, Justin M. Albury, Humberto Ibarguen Salazar, Hernán Asorey, M. I. Micheletti, Karl-Heinz Kampert, Antonella Castellina, Jonathan Biteau, J. Vicha, G. Farrar, Juan Pablo Gongora, K.-H. Becker, Nicolás González, Jose Chinellato, Alan Watson, H. Wilczyński, M. Suárez-Durán, Xavier Bertou, M. Perlin, Matias Tueros, Mihai Niculescu-Oglinzanu, M. Pimenta, I. Lhenry-Yvon, Jiri Blazek, E. De Vito, Giovanni Consolati, A. Zepeda, Gaetano Salina, Violet M. Harvey, D. Harari, Luis A. Nunez, Pedro Assis, P.R. Araújo Ferreira, Brian Fick, Piera Luisa Ghia, D. Lo Presti, S. J. De Jong, C. O. Escobar, A. Insolia, M. Kleifges, A.D. Supanitsky, H. Martinez, A. Etchegoyen, Marcus Niechciol, A. Taboada, J. Pȩkala, A. Fuster, Miguel Mostafa, Frank G. Schröder, Jarryd A. Day, A. Saftoiu, R.J. Barreira Luz, Tobias Winchen, Julien Manshanden, R. Conceição, A. Puyleart, Corinne Berat, M. Giller, Petr Schovanek, A.C. Cobos Cerutti, P.F. Gómez Vitale, Alina Mihaela Badescu, S. Querchfeld, Andres Travaini, E. Varela, J.D. Sanabria Gomez, Olena Tkachenko, V. Novotny, Ioana Caracas, Cristina Galea, J. R. T. de Mello Neto, L. Bonneau Arbeletche, A. Haungs, Rossella Caruso, A. Lucero, Fernando Catalani, J. Šupík, Carlo Ventura, Florian Lukas Briechle, Massimo Mastrodicasa, P. Ruehl, M. Schimassek, Caterina Trimarelli, Alena Bakalova, C. Hojvat, Jan Ebr, Ladislav Chytka, Samo Stanič, M. E. Bertaina, Markus Roth, M. HrabovskÃ, Jon Paul Lundquist, A. Menshikov, J. Hulsman, Juan Manuel González, P. Mantsch, B. L. Lago, P. Travnicek, Jacco Vink, H. Gemmeke, M. Unger, Jeffrey A. Johnsen, Z. Szadkowski, Gaia Silli, Isabel Goos, R. Squartini, A. Filipčič, D. Heck, Alfred Müller, H.O. Klages, Thomas Hebbeker, Sergio Dasso, Tristan Sudholz, S. Petrera, Marc Weber, A. Letessier-Selvon, Paula Gina Isar, M. del Río, Günter Sigl, Martín Miguel Freire, Roberto Mussa, P. Stassi, Radomir Smida, G. Medina-Tanco, A. A. Nucita, J. Rautenberg, A. Machado Payeras, B. García, R.C. Shellard, Q. Luce, F. Salamida, Maximilian Stadelmaier, R. López, Karen S. Caballero-Mora, R. M. de Almeida, A. Yushkov, Lorenzo Caccianiga, Lorenzo Cazon, G. Golup, Rodrigo Pelayo, Stijn Buitink, Martin Erdmann, François Montanet, J. de Jesús, A. Streich, Gioacchino Alex Anastasi, M. Wirtz, Eleonora Guido, Valerio Verzi, L. Nellen, Roger W Clay, Fernando Gollan, C. Morello, V. de Souza, Peter L. Biermann, Paolo Privitera, David Wittkowski, Olivier Deligny, Tomáš Fodran, Ugo Giaccari, Ioana Codrina Maris, A. C. Fauth, Carla Bonifazi, Jose A. Bellido, Fabio Convenga, G. C. Hill, I.D. Vergara Quispe, Jorge F. Soriano, Hernan Wahlberg, Ralph Engel, A. Parra, P. Ristori, M. Trini, I. Allekotte, M. J. Roncoroni, J. Pallotta, J. Ridky, A. M. Botti, Jörg R. Hörandel, H. J. Mathes, Stanislav Michal, J. Rodriguez Rojo, G. Matthiae, Fridtjof Feldbusch, Enrique Zas, Antonio Bueno, Fernando Contreras, Gualberto Avila, Dariusz Gora, John Farmer, Alan Coleman, Maria-Teresa Dova, M. R. Hampel, S. J. Saffi, F. Pedreira, Raul Sarmento, R.C. dos Anjos, Felix Schlüter, Adriana Vásquez-Ramírez, M. Palatka, Fabian Gobbi, Jesús Peña-Rodríguez, M.A. Leigui de Oliveira, High Energy Astrophys. & Astropart. Phys (API, FNWI), Aab, A., Abreu, P., Aglietta, M., Albury, J. M., Allekotte, I., Almela, A., Alvarez-Muniz, J., Alves Batista, R., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Araujo Ferreira, P. R., Asorey, H., Assis, P., Avila, G., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Barreira Luz, R. J., Becker, K. H., Bellido, J. A., Berat, C., Bertaina, M. E., Bertou, X., Biermann, P. L., Bister, T., Biteau, J., Blazek, J., Bleve, C., Bohacova, M., Boncioli, D., Bonifazi, C., Bonneau Arbeletche, L., Borodai, N., Botti, A. M., Brack, J., Bretz, T., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Caballero-Mora, K. S., Caccianiga, L., Canfora, F., Caracas, I., Carceller, J. M., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Choi, K., Chudoba, J., Chytka, L., Clay, R. W., Cobos Cerutti, A. C., Colalillo, R., Coleman, A., Coluccia, M. R., Conceicao, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., Covault, C. E., Dasso, S., Daumiller, K., Dawson, B. R., Day, J. A., de Almeida, R. M., de Jesus, J., de Jong, S. J., de Mauro, G., de Mello Neto, J. R. T., de Mitri, I., de Oliveira, J., de Oliveira Franco, D., de Souza, V., de Vito, E., Debatin, J., del Rio, M., Deligny, O., Di Matteo, A., Dobrigkeit, C., D'Olivo, J. C., dos Anjos, R. C., Dova, M. T., Ebr, J., Engel, R., Epicoco, I., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fick, B., Figueira, J. M., Filipcic, A., Fodran, T., Freire, M. M., Fujii, T., Fuster, A., Galea, C., Galelli, C., Garcia, B., Garcia Vegas, A. L., Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Giller, M., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Gomez Berisso, M., Gomez Vitale, P. F., Gongora, J. P., Gonzalez, J. M., Gonzalez, N., Goos, I., Gora, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Hahn, S., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Hill, G. C., Hojvat, C., Horandel, J. R., Horvath, P., Hrabovsky, M., Huege, T., Hulsman, J., Insolia, A., Isar, P. G., Johnsen, J. A., Jurysek, J., Kaapa, A., Kampert, K. H., Keilhauer, B., Kemp, J., Klages, H. O., Kleifges, M., Kleinfeller, J., Kopke, M., Lago, B. L., Lang, R. G., Langner, N., Leigui de Oliveira, M. A., Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Lo Presti, D., Lopes, L., Lopez, R., Luce, Q., Lucero, A., Lundquist, J. P., Machado Payeras, A., Mancarella, G., Mandat, D., Manning, B. C., Manshanden, J., Mantsch, P., Marafico, S., Mariazzi, A. G., Maris, I. C., Marsella, G., Martello, D., Martinez, H., Martinez Bravo, O., Mastrodicasa, M., Mathes, H. J., Matthews, J., Matthiae, G., Mayotte, E., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Merenda, K. -D., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morello, C., Mostafa, M., Muller, A. L., Muller, M. A., Mulrey, K., Mussa, R., Muzio, M., Namasaka, W. M., Nellen, L., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nozka, L., Nucita, A., Nunez, L. A., Palatka, M., Pallotta, J., Papenbreer, P., Parente, G., Parra, A., Pech, M., Pedreira, F., Pekala, J., Pelayo, R., Pena-Rodriguez, J., Perez Armand, J., Perlin, M., Perrone, L., Petrera, S., Pierog, T., Pimenta, M., Pirronello, V., Platino, M., Pont, B., Pothast, M., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Ristori, P., Rizi, V., Rodrigues de Carvalho, W., Rodriguez Rojo, J., Roncoroni, M. J., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saffi, S. J., Saftoiu, A., Salamida, F., Salazar, H., Salina, G., Sanabria Gomez, J. D., Sanchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sarmiento-Cano, C., Sato, R., Savina, P., Schafer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schluter, F., Schmidt, D., Scholten, O., Schovanek, P., Schroder, F. G., Schroder, S., Schulte, J., Sciutto, S. J., Scornavacche, M., Shellard, R. C., Sigl, G., Silli, G., Sima, O., Smida, R., Sommers, P., Soriano, J. F., Souchard, J., Squartini, R., Stadelmaier, M., Stanca, D., Stanic, S., Stasielak, J., Stassi, P., Streich, A., Suarez-Duran, M., Sudholz, T., Suomijarvi, T., Supanitsky, A. D., Supik, J., Szadkowski, Z., Taboada, A., Tapia, A., Timmermans, C., Tkachenko, O., Tobiska, P., Todero Peixoto, C. J., Tome, B., Travaini, A., Travnicek, P., Trimarelli, C., Trini, M., Tueros, M., Ulrich, R., Unger, M., Vaclavek, L., Vacula, M., Valdes Galicia, J. F., Valore, L., Varela, E., Varma, V. K. C., Vasquez-Ramirez, A., Veberic, D., Ventura, C., Vergara Quispe, I. D., Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Wahlberg, H., Watson, A. A., Weber, M., Weindl, A., Wiencke, L., Wilczynski, H., Winchen, T., Wirtz, M., Wittkowski, D., Wundheiler, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., Zehrer, L., Zepeda, A., Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Institut de Physique Nucléaire d'Orsay (IPNO), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Pierre Auger, Physics, Aab A., Abreu P., Aglietta M., Albury J.M., Allekotte I., Almela A., Alvarez-Muniz J., Alves Batista R., Anastasi G.A., Anchordoqui L., Andrada B., Andringa S., Aramo C., Araujo Ferreira P.R., Asorey H., Assis P., Avila G., Badescu A.M., Bakalova A., Balaceanu A., Barbato F., Barreira Luz R.J., Becker K.H., Bellido J.A., Berat C., Bertaina M.E., Bertou X., Biermann P.L., Bister T., Biteau J., Blazek J., Bleve C., Bohacova M., Boncioli D., Bonifazi C., Bonneau Arbeletche L., Borodai N., Botti A.M., Brack J., Bretz T., Briechle F.L., Buchholz P., Bueno A., Buitink S., Buscemi M., Caballero-Mora K.S., Caccianiga L., Canfora F., Caracas I., Carceller J.M., Caruso R., Castellina A., Catalani F., Cataldi G., Cazon L., Cerda M., Chinellato J.A., Choi K., Chudoba J., Chytka L., Clay R.W., Cobos Cerutti A.C., Colalillo R., Coleman A., Coluccia M.R., Conceicao R., Condorelli A., Consolati G., Contreras F., Convenga F., Covault C.E., Dasso S., Daumiller K., Dawson B.R., Day J.A., de Almeida R.M., de Jesus J., de Jong S.J., de Mauro G., de Mello Neto J.R.T., de Mitri I., de Oliveira J., de Oliveira Franco D., de Souza V., de Vito E., Debatin J., del Rio M., Deligny O., Di Matteo A., Dobrigkeit C., D'Olivo J.C., dos Anjos R.C., Dova M.T., Ebr J., Engel R., Epicoco I., Erdmann M., Escobar C.O., Etchegoyen A., Falcke H., Farmer J., Farrar G., Fauth A.C., Fazzini N., Feldbusch F., Fenu F., Fick B., Figueira J.M., Filipcic A., Fodran T., Freire M.M., Fujii T., Fuster A., Galea C., Galelli C., Garcia B., Garcia Vegas A.L., Gemmeke H., Gesualdi F., Gherghel-Lascu A., Ghia P.L., Giaccari U., Giammarchi M., Giller M., Glombitza J., Gobbi F., Gollan F., Golup G., Gomez Berisso M., Gomez Vitale P.F., Gongora J.P., Gonzalez J.M., Gonzalez N., Goos I., Gora D., Gorgi A., Gottowik M., Grubb T.D., Guarino F., Guedes G.P., Guido E., Hahn S., Hampel M.R., Hansen P., Harari D., Harvey V.M., Haungs A., Hebbeker T., Heck D., Hill G.C., Hojvat C., Horandel J.R., Horvath P., Hrabovsky M., Huege T., Hulsman J., Insolia A., Isar P.G., Johnsen J.A., Jurysek J., Kaapa A., Kampert K.H., Keilhauer B., Kemp J., Klages H.O., Kleifges M., Kleinfeller J., Kopke M., Lago B.L., Lang R.G., Langner N., Leigui de Oliveira M.A., Lenok V., Letessier-Selvon A., Lhenry-Yvon I., Lo Presti D., Lopes L., Lopez R., Luce Q., Lucero A., Lundquist J.P., Machado Payeras A., Mancarella G., Mandat D., Manning B.C., Manshanden J., Mantsch P., Marafico S., Mariazzi A.G., Maris I.C., Marsella G., Martello D., Martinez H., Martinez Bravo O., Mastrodicasa M., Mathes H.J., Matthews J., Matthiae G., Mayotte E., Mazur P.O., Medina-Tanco G., Melo D., Menshikov A., Merenda K.-D., Michal S., Micheletti M.I., Miramonti L., Mollerach S., Montanet F., Morello C., Mostafa M., Muller A.L., Muller M.A., Mulrey K., Mussa R., Muzio M., Namasaka W.M., Nellen L., Niculescu-Oglinzanu M., Niechciol M., Nitz D., Nosek D., Novotny V., Nozka L., Nucita A., Nunez L.A., Palatka M., Pallotta J., Papenbreer P., Parente G., Parra A., Pech M., Pedreira F., Pekala J., Pelayo R., Pena-Rodriguez J., Perez Armand J., Perlin M., Perrone L., Petrera S., Pierog T., Pimenta M., Pirronello V., Platino M., Pont B., Pothast M., Privitera P., Prouza M., Puyleart A., Querchfeld S., Rautenberg J., Ravignani D., Reininghaus M., Ridky J., Riehn F., Risse M., Ristori P., Rizi V., Rodrigues de Carvalho W., Rodriguez Rojo J., Roncoroni M.J., Roth M., Roulet E., Rovero A.C., Ruehl P., Saffi S.J., Saftoiu A., Salamida F., Salazar H., Salina G., Sanabria Gomez J.D., Sanchez F., Santos E.M., Santos E., Sarazin F., Sarmento R., Sarmiento-Cano C., Sato R., Savina P., Schafer C.M., Scherini V., Schieler H., Schimassek M., Schimp M., Schluter F., Schmidt D., Scholten O., Schovanek P., Schroder F.G., Schroder S., Schulte J., Sciutto S.J., Scornavacche M., Shellard R.C., Sigl G., Silli G., Sima O., Smida R., Sommers P., Soriano J.F., Souchard J., Squartini R., Stadelmaier M., Stanca D., Stanic S., Stasielak J., Stassi P., Streich A., Suarez-Duran M., Sudholz T., Suomijarvi T., Supanitsky A.D., Supik J., Szadkowski Z., Taboada A., Tapia A., Timmermans C., Tkachenko O., Tobiska P., Todero Peixoto C.J., Tome B., Travaini A., Travnicek P., Trimarelli C., Trini M., Tueros M., Ulrich R., Unger M., Vaclavek L., Vacula M., Valdes Galicia J.F., Valore L., Varela E., Varma V.K.C., Vasquez-Ramirez A., Veberic D., Ventura C., Vergara Quispe I.D., Verzi V., Vicha J., Vink J., Vorobiov S., Wahlberg H., Watson A.A., Weber M., Weindl A., Wiencke L., Wilczynski H., Winchen T., Wirtz M., Wittkowski D., Wundheiler B., Yushkov A., Zapparrata O., Zas E., Zavrtanik D., Zavrtanik M., Zehrer L., Zepeda A., and Research unit Astroparticle Physics

Subjects
Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, Astronomy, Performance of High Energy Physics Detector, 01 natural sciences, 7. Clean energy, Etc), 030218 nuclear medicine & medical imaging, 0302 clinical medicine, Front-end electronics for detector readout, APDs, Instrumentation, physics.ins-det, Photon detectors for UV, Mathematical Physics, Instrumentation et méthodes en physique, EBCCDs, Visible and IR photons (solid-state) (PIN diodes, APDs, Si-PMTs, G-APDs, CCDs, EBCCDs, EMCCDs, CMOS imagers, etc), electronics, Settore FIS/01 - Fisica Sperimentale, Calibration and fitting methods, Performance of High Energy Physics Detectors, Photon detectors for UV, visible and IR photons (solid-state) (PIN diodes, APDs, Si-PMTs, G-APDs, CCDs, EBCCDs, EMCCDs, CMOS imagers, etc), Astrophysics::Instrumentation and Methods for Astrophysics, Si-PMTs, Instrumentation and Detectors (physics.ins-det), charged particle, CCDs, Cluster finding, CMOS imagers, EMCCDs, Pattern recognition, G-APDs, Visible and IR photons (solid-state) (PIN diodes, Auger, observatory, density [muon], Pattern recognition, cluster finding, calibration and fitting method, Christian ministry, upgrade, ddc:620, Astrophysics - Instrumentation and Methods for Astrophysics, performance, atmosphere [showers], Land access, Cherenkov counter: water, air, Astrophysics::High Energy Astrophysical Phenomena, UHE [cosmic radiation], FOS: Physical sciences, 03 medical and health sciences, Political science, 0103 physical sciences, muon: density, photomultiplier: silicon, High Energy Physics, cosmic radiation: UHE, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], ddc:610, Instrumentation and Methods for Astrophysics (astro-ph.IM), Engineering & allied operations, scintillation counter, showers: atmosphere, 010308 nuclear & particles physics, water [Cherenkov counter], Autres mathématiques, Research council, efficiency, Experimental High Energy Physics, silicon [photomultiplier], High Energy Physics::Experiment, Humanities, RAIOS CÓSMICOS, astro-ph.IM
Abstract

The successful installation, commissioning, and operation of the Pierre Auger Observatory would not have been possible without the strong commitment and effort from the technical and administrative staff in Malargue. We are very grateful to the following agencies and organizations for financial support: Argentina -Comision Nacional de Energia Atomica; Agencia Nacional de Promocion Cientifica y Tecnologica (ANPCyT); Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET); Gobierno de la Provincia de Mendoza; Municipalidad de Malargue; NDM Holdings and Valle Las Lenas; in gratitude for their continuing cooperation over land access; Australia -the Australian Research Council; Brazil -Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq); Financiadora de Estudos e Projetos (FINEP); Fundacao de Amparo a Pesquisa do Estado de Rio de Janeiro (FAPERJ); Sao Paulo Research Foundation (FAPESP) Grants No. 2019/10151-2, No. 2010/07359-6 and No. 1999/05404-3; Ministerio da Ciencia, Tecnologia, Inovacoes e Comunicacoes (MCTIC); Czech Republic Grant No. MSMT CR LTT18004, LM2015038, LM2018102, CZ.02.1.01/0.0/0.0/16_013/0001402, CZ.02.1.01/0.0/0.0/18_046/0016010 and CZ.02.1.01/0.0/0.0/17_049/0008422; France -Centre de Calcul IN2P3/CNRS; Centre National de la Recherche Scientifique (CNRS); Conseil Regional Ile-de-France; Departement Physique Nucleaire et Corpusculaire (PNC-IN2P3/CNRS); Departement Sciences de l'Univers (SDU-INSU/CNRS); Institut Lagrange de Paris (ILP) Grant No. LABEX ANR-10-LABX-63 within the Investissements d'Avenir Programme Grant No. ANR-11-IDEX-0004-02; Germany-Bundesministerium fur Bildung und Forschung (BMBF); Deutsche Forschungsgemeinschaft (DFG); Finanzministerium Baden-Wurttemberg; Helmholtz Alliance for Astroparticle Physics (HAP); Helmholtz-Gemeinschaft Deutscher Forschungszentren (HGF); Ministerium fur Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen; Ministerium fur Wissenschaft, Forschung und Kunst des Landes Baden-Wurttemberg; Italy-Istituto Nazionale di Fisica Nucleare (INFN); Istituto Nazionale di Astrofisica (INAF); Ministero dell'Istruzione, dell'Universita e della Ricerca (MIUR); CETEMPS Center of Excellence; Ministero degli Affari Esteri (MAE); Mexico-Consejo Nacional de Ciencia y Tecnologia (CONACYT) No. 167733; Universidad Nacional Autonoma de Mexico (UNAM); PAPIIT DGAPA-UNAM; The Netherlands -Ministry of Education, Culture and Science; Netherlands Organisation for Scientific Research (NWO); Dutch national e-infrastructure with the support of SURF Cooperative; Poland-Ministry of Science and Higher Education, grant No. DIR/WK/2018/11; National Science Centre, Grants No. 2013/08/M/ST9/00322, No. 2016/23/B/ST9/01635 and No. HARMONIA 5-2013/10/M/ST9/00062, UMO-2016/22/M/ST9/00198; Portugal -Portuguese national funds and FEDER funds within Programa Operacional Factores de Competitividade through Fundacao para a Ciencia e a Tecnologia (COMPETE); Romania-Romanian Ministry of Education and Research, the Program Nucleu within MCI(PN19150201/16N/2019 and PN19060102) and project PN-III-P1-1.2-PCCDI-2017-0839/19PCCDI/2018 within PNCDI III; Slovenia -Slovenian Research Agency, grants P1-0031, P1-0385, I0-0033, N1-0111; Spain-Ministerio de Economia, Industria y Competitividad (FPA2017-85114-P and FPA2017-85197-P), Xunta de Galicia (ED431C 2017/07), Junta de Andalucia (SOMM17/6104/UGR), Feder Funds, RENATA Red Nacional Tematica de Astroparticulas (FPA2015-68783-REDT) and Maria de Maeztu Unit of Excellence (MDM-2016-0692); U.S.A. -Department of Energy, Contracts No. DE-AC02-07CH11359, No. DE-FR02-04ER41300, No. DE-FG02-99ER41107 and No. DE-SC0011689; National Science Foundation, Grant No. 0450696; The Grainger Foundation; Marie Curie-IRSES/EPLANET; European Particle Physics Latin American Network; and UNESCO., AMIGA (Auger Muons and Infill for the Ground Array) is an upgrade of the Pierre Auger Observatory to complement the study of ultra-high-energy cosmic rays (UHECR) by measuring the muon content of extensive air showers (EAS). It consists of an array of 61 water Cherenkov detectors on a denser spacing in combination with underground scintillation detectors used for muon density measurement. Each detector is composed of three scintillation modules, with 10 m(2) detection area per module, buried at 2.3 m depth, resulting in a total detection area of 30 m(2). Silicon photomultiplier sensors (SiPM) measure the amount of scintillation light generated by charged particles traversing the modules. In this paper, the design of the front-end electronics to process the signals of those SiPMs and test results from the laboratory and from the Pierre Auger Observatory are described. Compared to our previous prototype, the new electronics shows a higher performance, higher efficiency and lower power consumption, and it has a new acquisition system with increased dynamic range that allows measurements closer to the shower core. The new acquisition system is based on the measurement of the total charge signal that the muonic component of the cosmic ray shower generates in the detector., Argentina - Comision Nacional de Energia Atomica, Argentina - Agencia Nacional de Promocion Cientifica y Tecnologica (ANPCyT), Argentina - Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Argentina - Gobierno de la Provincia de Mendoza, Argentina - Municipalidad de Malargue, Argentina - NDM Holdings, Argentina - Valle Las Lenas, Australian Research Council, Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPQ) Fundacao de Apoio a Pesquisa do Distrito Federal (FAPDF) Brazil - Financiadora de Estudos e Projetos (FINEP), Fundacao Carlos Chagas Filho de Amparo a Pesquisa do Estado do Rio De Janeiro (FAPERJ), Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) 2019/10151-2 2010/07359-6 1999/05404-3, Brazil - Ministerio da Ciencia, Tecnologia, Inovacoes e Comunicacoes (MCTIC), Brazil - Czech Republic Grant MSMT CR LTT18004 LM2015038 LM2018102 CZ.02.1.01/0.0/0.0/16_013/0001402 CZ.02.1.01/0.0/0.0/18_046/0016010 CZ.02.1.01/0.0/0.0/17_049/0008422, France - Centre de Calcul IN2P3/CNRS, Centre National de la Recherche Scientifique (CNRS), France - Conseil Regional Ile-de-France, France - Departement Physique Nucleaire et Corpusculaire (PNC-IN2P3/CNRS), France - Departement Sciences de l'Univers (SDU-INSU/CNRS), French National Research Agency (ANR) LABEX ANR-10-LABX-63, Institut Lagrange de Paris (ILP) within the Investissements d'Avenir Programme ANR-11-IDEX-0004-02, Federal Ministry of Education & Research (BMBF), Bundesministerium fur Bildung und Forschung (BMBF), German Research Foundation (DFG), Germany - Finanzministerium Baden-Wurttemberg, Germany - Helmholtz Alliance for Astroparticle Physics (HAP), Germany - Helmholtz-Gemeinschaft Deutscher Forschungszentren (HGF), Germany - Ministerium fur Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen, Germany - Ministerium fur Wissenschaft, Forschung und Kunst des Landes Baden-Wurttemberg, Italy - Istituto Nazionale di Fisica Nucleare (INFN), Italy - Istituto Nazionale di Astrofisica (INAF), Italy - Ministero dell'Istruzione, dell'Universita e della Ricerca (MIUR), Italy - CETEMPS Center of Excellence, Consejo Nacional de Ciencia y Tecnologia (CONACyT) 167733, Mexico - Universidad Nacional Autonoma de Mexico (UNAM), Mexico - PAPIIT DGAPA-UNAM, Netherlands - Ministry of Education, Culture and Science, Netherlands Organization for Scientific Research (NWO), Netherlands Organisation for Scientific Research (NWO), The Netherlands - SURF Cooperative, Poland - Ministry of Science and Higher Education DIR/WK/2018/11 Poland - National Science Centre 2013/08/M/ST9/00322 2016/23/B/ST9/01635 HARMONIA 5-2013/10/M/ST9/00062 UMO-2016/22/M/ST9/00198, Portugal - Portuguese national funds Portugal - FEDER funds within Programa Operacional Factores de Competitividade through Fundacao para a Ciencia e a Tecnologia (COMPETE), Romania - Romanian Ministry of Education and Research Romania - Program Nucleu within MCI PN19150201/16N/2019 PN19060102 Romania - PNCDI III PN-III-P1-1.2-PCCDI-2017-0839/19PCCDI/2018, Slovenian Research Agency - Slovenia P1-0031 P1-0385 I0-0033 N1-0111, Spain - Ministerio de Economia, Industria y Competitividad FPA2017-85114-P FPA2017-85197-P, Spain - Xunta de Galicia ED431C 2017/07, Junta de Andalucia SOMM17/6104/UGR, Spain - Feder Funds, Spain - RENATA Red Nacional Tematica de Astroparticulas FPA2015-68783-REDT, Spain - Maria de Maeztu Unit of Excellence MDM-2016-0692, United States Department of Energy (DOE) DE-AC02-07CH11359, National Science Foundation (NSF) 0450696, U.S.A. - Grainger Foundation U.S.A. - Marie Curie-IRSES/EPLANET U.S.A. - European Particle Physics Latin American Network U.S.A. - UNESCO, Italy - Ministero degli Affari Esteri (MAE), The Netherlands - Dutch national e-infrastructure

Published
2021
Full Text
View/download PDF

50. Sensitivity of the Cherenkov Telescope Array for probing cosmology and fundamental physics with gamma-ray propagation

Author

J.-P. Lenain, A. Domínguez, Jonathan Ivor Davies, T. Armstrong, A. A. Zdziarski, F. Gianotti, M. Balbo, E. O. Angüner, M. Marculewicz, Alasdair E. Gent, Alice Donini, Olivier Hervet, Henry Przybilski, Giacomo Principe, G. Leto, M. Peresano, Stefano Covino, P. A. Caraveo, Gianpiero Tagliaferri, D. de Martino, V. V. Vassiliev, D. Cauz, F. R. Pantaleo, U. Barres de Almeida, Pietro Bruno, E. Lindfors, M. Zavrtanik, G. Hughes, Miriam Lucio Martinez, P. Bordas, Y. Suda, G. S. Varner, R. Rando, K. Cerny, S. Pita, Csaba Balázs, E. Fiandrini, Michael Backes, Tomohiko Oka, Massimo Persic, Andrea Chiavassa, Johannes Veh, A. Stamerra, Fabrizio Tavecchio, B. Biasuzzi, Michael Punch, Soebur Razzaque, F. D'Ammando, P. I. Batista, Bruna Bertucci, F. Longo, Francesco Gabriele Saturni, Michael G. Burton, Bohdan Hnatyk, P. Sangiorgi, E. M. Santos, D. Nosek, Gagik Tovmassian, J. L. Dournaux, Pedro L. Luque-Escamilla, A. Aguirre-Santaella, M. Orienti, Lluis Font, Andreas Quirrenbach, Philippe Laporte, Ralf Kissmann, Francesco Lucarelli, K. Noda, I. Jiménez Martínez, G. Romeo, Wystan Benbow, P. Romano, B. Bi, J. Grube, H.-S. Zechlin, Giacomo Bonnoli, Martin White, J. P. Osborne, Enrico Cascone, Marek Jamrozy, C. Alispach, Miroslav Pech, O. Cuevas, Petr Schovanek, K. Hayashi, V. I. Zhdanov, Javier Coronado-Blázquez, D. Medina Miranda, Barbara Balmaverde, E. de Ona Wilhelmi, Frank M. Rieger, A. Shalchi, J. M. Paredes, Ruben Alfaro, N. Giglietto, Diego Falceta-Gonçalves, Helene Sol, Rodolfo Carosi, Ayan Acharyya, Dominik Elsässer, S. Vercellone, D. Pimentel, T. Mizuno, Alessandro Bruno, Juan Abel Barrio, K. Kosack, Mauro Orlandini, Rodrigo Guedes Lang, P. Marquez, Adrian Biland, Y. Kobayashi, Nicholas F. H Tothill, M. de Naurois, Daniele Spiga, Lili Yang, L. Tibaldo, Pavel Horvath, M. Lopez, I. Sadeh, Marek Nikolajuk, F. Schüssler, Reshmi Mukherjee, Gianpaolo Vettolani, Jürgen Knödlseder, Daniel Nieto, R. Hnatyk, German Martinez, Diego F. Torres, Farinaldo S. Queiroz, N. Parmiggiani, G. Lamanna, Marcos Santander, S. Fegan, I. Vovk, M. Sánchez-Conde, Wiphu Rujopakarn, Norita Kawanaka, R. C. Shellard, Michael C. B. Ashley, J. Jurysek, Francisco J. Franco, Samuel Timothy Spencer, E. Rebert, J. Morales Merino, M. Pecimotika, Marco Berton, Regis Terrier, G. A. Beck, Carlos Díaz, J. L. Contreras, G. Zaharijas, R. Moderski, José-María Martí, A. Insolia, D. Zavrtanik, K. Kohri, Ladislav Chytka, T. Grabarczyk, A. Zech, M. Garczarczyk, Anastasia Sokolenko, J. Lefaucheur, R. A. Cameron, Moritz Hütten, S. Karkar, K. Pfrang, V. Poireau, Asaf Pe'er, A. Reimer, Fabio Acero, L. Freixas Coromina, David Sánchez, Jonathan S. Lapington, Konstantinos N. Gourgouliatos, J.R. Hörandel, Mario Buscemi, Francesco Dazzi, Abelardo Moralejo, J. Bolmont, R. White, A. Rosales de Leon, J. Prast, Sabrina Einecke, Roberto Aloisio, Yvonne Becherini, Andreas Specovius, Shohei Yanagita, Juan Cortina, Miroslav Hrabovsky, Petr Janecek, D. Depaoli, Lucas Taylor, U. Schwanke, H. Abdalla, S. Recchia, Manuela Mallamaci, M. K. Daniel, Q. Feng, L. Baroncelli, Hiromitsu Takahashi, Susumu Inoue, U. Straumann, Masatoshi Ohishi, Roberto Capuzzo-Dolcetta, Nu. Komin, Federico Russo, R. de Cássia dos Anjos, Y. Ohira, Ferdinando Giordano, Nagisa Hiroshima, E. Garcia, Gavin Rowell, V. Bozhilov, Maxim V. Barkov, Dario Hrupec, I. Oya, F. Salesa Greus, Anna Wolter, M. Živec, R. Belmont, R. Adam, T. Reposeur, J. Rico, A. W. Chen, G. Pühlhofer, H. Prokoph, Stefan Wagner, F. Di Pierro, Fabrizio Bocchino, M. de Bony de Lavergne, A. Kong, Masha Chernyakova, M. Pohl, M. Vazquez Acosta, A. Nagai, A. Brill, Dusan Mandat, Jonathan Biteau, Martin Makariev, Catherine Boisson, E. Lyard, Gilles Maurin, H. Martínez-Huerta, Oscar Blanch, Bernd Schleicher, M. Minev, A. Berti, James E. M. Watson, Talvikki Hovatta, M. Valentino, Luis Ángel Tejedor, Elena Amato, M. V. Fonseca, Anderson Caproni, L. Mohrmann, P. Reichherzer, R. L. C. Starling, M. Seglar Arroyo, E. Orlando, B. Rudak, G. Emery, J. A. Green, Salvo Scuderi, M. Prouza, Tom Richtler, Bartłomiej Pilszyk, A. Carosi, Jacek Niemiec, Wolfgang Rhode, G. Ambrosi, D. Ribeiro, A. Wierzcholska, A. Ghalumyan, Eugenio Bottacini, Sylvain Chaty, A. Baquero Larriva, Olaf Reimer, D. Horan, Fabian Leuschner, T. Di Girolamo, Alessandro Caccianiga, Martin Will, Saverio Lombardi, A. Fiasson, Mitsunari Takahashi, J. J. Rodríguez Vázquez, B. De Lotto, V. De Caprio, Stefano Truzzi, Dirk L. Hoffmann, M. Vecchi, Antonio Pagliaro, Jose J. Gonzalez, Wenwu Tian, R. Della Ceca, J. Becerra González, S. Nozaki, T. Vuillaume, S. L. Lloyd, Maria Ionica, Elisabetta Bissaldi, Petr Travnicek, Y. Ascasibar, Carlo Vigorito, F. Tuossenel, Malcolm Fairbairn, O. Martinez, Marco Iarlori, Serena Loporchio, Alessandro Costa, R. Pillera, A. Morselli, M. Heller, Jaime Rosado, E. M. de Gouveia Dal Pino, V. Vitale, A. M. Brown, E. Molina, Takashi Saito, A. De Angelis, Thomas Murach, R. A. Ong, J. Bregeon, P. T. O'Brien, Mikael Jacquemont, P. Cristofari, Francesco Conte, Lab Saha, R. Walter, Vitalii Sliusar, W. Jin, Vito Conforti, N. Produit, H. Siejkowski, Lovro Pavletić, Carole Mundell, G. Rodriguez Fernandez, J. F. Glicenstein, Paresh Sharma, C. Delgado, Vladimír Karas, Luca Foffano, J. Granot, Manuel Meyer, Reiko Orito, G. Umana, G. Chiaro, D. Tonev, R. Wiemann, G. Manicò, J.C. Rodriguez Ramirez, Luca Tosti, Markus Böttcher, Andrea Bulgarelli, C. Díaz-Bahamondes, I. Jung-Richardt, Karol Seweryn, P. Piatteli, Agnieszka Slowikowska, Jan Ebr, M. Ostrowski, J. L. Rodriguez, D. della Volpe, Ermanno Pietropaolo, M. Caprai, T. Montaruli, A. Lopez, Rodrigo Nemmen, R. R. Prado, L. Arrabito, Atreyee Sinha, C. van Eldik, Serguei Vorobiov, Hidetoshi Sano, J. Alfaro, Sabrina Casanova, G. Maneva, B. Vallage, Valentina Fioretti, Carmelo Evoli, P. Kaaret, B. A. W. Mode, Agnieszka Majczyna, Sebastian Diebold, A. Scherer, F. de Palma, S. Hernández Cadena, V. Beshley, T.R.N. Ekoume, David A. Williams, M. Capasso, A. Halim, Alison Mitchell, Tomislav Terzić, Paola Grandi, Lorenzo Amati, Christopher Eckner, David Gascon, K. Nishijima, J. Becker Tjus, B. Khélifi, G. Galanti, Jamie Holder, Vincenzo Rizi, Orel Gueta, Daniele Gaggero, F. Pintore, Utane Sawangwit, Vassil Verguilov, Heide Costantini, F. Arqueros, Daniel Kerszberg, P. M. Chadwick, D. Zarić, Marc Ribó, Olga Sergijenko, Dario Grasso, Hidetoshi Kubo, Daniela Dorner, T. Stolarczyk, M. Gaug, R. Alves Batista, Elisa Bernardini, Vikram V. Dwarkadas, Jim Hinton, Jelena Strišković, Andreu Sanuy, M. Servillat, V. Barbosa Martins, Giovanni Bonanno, S. Gunji, R. Wischnewski, S. Sarkar, Gianluca Giavitto, Takeshi Nakamori, M. Palatka, Maria Letizia Pumo, Camilla Maggio, M. Zacharias, Katsuaki Asano, Valerio Vagelli, Anton Dmytriiev, Ryo Yamazaki, M. Vacula, P. Goldoni, Gilles Fontaine, Hiroshi Muraishi, D. Mazin, Samo Stanič, G. Ghirlanda, M. Polo, M. Nievas, M. Lemoine-Goumard, Oleh Petruk, Jose Miguel Miranda, M. Iori, A. Marcowith, Y. Renier, Satoshi Fukami, M. Roncadelli, F. Leone, Takanori Yoshikoshi, Ana Luiza d'Ávila Viana, Y. Fukui, Max Harvey, Sera Markoff, I. Agudo, P. Temnikov, Vincenzo Testa, R. López-Coto, J.D. Mbarubucyeye, Tjark Miener, David Paneque, V. Gammaldi, T. Hassan Collado, H. Abe, L. Bonneau Arbeletche, S. D. Vergani, Sasa Micanovic, P. Vallania, Marina Manganaro, Elena Torresi, M. Giarrusso, G. Ferrand, Paweł Świerk, B. Patricelli, Matteo Cerruti, N. La Palombara, D. Morcuende-Parrilla, V. de Souza, Toshiaki Inada, Yasushi Fukazawa, Werner Hofmann, Michele Doro, E. Pueschel, A. Araudo, E. Sciacca, Thomas Lohse, A. Djannati-Ataï, Abdalla, H., Abe, H., Acero, F., Acharyya, A., Adam, R., Agudo, I., Aguirre-Santaella, A., Alfaro, R., Alfaro, J., Alispach, C., Aloisio, R., Alves Batista, R., Amati, L., Amato, E., Ambrosi, G., Ang??ner, E. O., Araudo, A., Armstrong, T., Arqueros, F., Arrabito, L., Asano, K., Ascas??bar, Y., Ashley, M., Backes, M., Balazs, C., Balbo, M., Balmaverde, B., Baquero Larriva, A., Barbosa Martins, V., Barkov, M., Baroncelli, L., Barres de Almeida, U., Barrio, J. A., Batista, P. -I., Becerra Gonz??lez, J., Becherini, Y., Beck, G., Becker Tjus, J., Belmont, R., Benbow, W., Bernardini, E., Berti, A., Berton, M., Bertucci, B., Beshley, V., Bi, B., Biasuzzi, B., Biland, A., Bissaldi, E., Biteau, J., Blanch, O., Bocchino, F., Boisson, C., Bolmont, J., Bonanno, G., Bonneau Arbeletche, L., Bonnoli, G., Bordas, P., Bottacini, E., B??ttcher, M., Bozhilov, V., Bregeon, J., Brill, A., Brown, A. M., Bruno, P., Bruno, A., Bulgarelli, A., Burton, M., Buscemi, M., Caccianiga, A., Cameron, R., Capasso, M., Caprai, M., Caproni, A., Capuzzo-Dolcetta, R., Caraveo, P., Carosi, R., Carosi, A., Casanova, S., Cascone, E., Cauz, D., Cerny, K., Cerruti, M., Chadwick, P., Chaty, S., Chen, A., Chernyakova, M., Chiaro, G., Chiavassa, A., Chytka, L., Conforti, V., Conte, F., Contreras, J. L., Coronado-Blazquez, J., Cortina, J., Costa, A., Costantini, H., Covino, S., Cristofari, P., Cuevas, O., D'Ammando, F., Daniel, M. K., Davies, J., Dazzi, F., De Angelis, A., de Bony de Lavergne, M., De Caprio, V., de C??ssia dos Anjos, R., de Gouveia Dal Pino, E. M., De Lotto, B., De Martino, D., de Naurois, M., de O??a Wilhelmi, E., De Palma, F., de Souza, V., Delgado, C., Della Ceca, R., della Volpe, D., Depaoli, D., Di Girolamo, T., Di Pierro, F., D??az, C., D??az-Bahamondes, C., Diebold, S., Djannati-Ata??, A., Dmytriiev, A., Dom??nguez, A., Donini, A., Dorner, D., Doro, M., Dournaux, J., Dwarkadas, V. V., Ebr, J., Eckner, C., Einecke, S., Ekoume, T. R. N., Els??sser, D., Emery, G., Evoli, C., Fairbairn, M., Falceta-Goncalves, D., Fegan, S., Feng, Q., Ferrand, G., Fiandrini, E., Fiasson, A., Fioretti, V., Foffano, L., Fonseca, M. V., Font, L., Fontaine, G., Franco, F. J., Freixas Coromina, L., Fukami, S., Fukazawa, Y., Fukui, Y., Gaggero, D., Galanti, G., Gammaldi, V., Garcia, E., Garczarczyk, M., Gascon, D., Gaug, M., Gent, A., Ghalumyan, A., Ghirlanda, G., Gianotti, F., Giarrusso, M., Giavitto, G., Giglietto, N., Giordano, F., Glicenstein, J., Goldoni, P., Gonz??lez, J. M., Gourgouliatos, K., Grabarczyk, T., Grandi, P., Granot, J., Grasso, D., Green, J., Grube, J., Gueta, O., Gunji, S., Halim, A., Harvey, M., Hassan Collado, T., Hayashi, K., Heller, M., Hern??ndez Cadena, S., Hervet, O., Hinton, J., Hiroshima, N., Hnatyk, B., Hnatyk, R., Hoffmann, D., Hofmann, W., Holder, J., Horan, D., H??randel, J., Horvath, P., Hovatta, T., Hrabovsky, M., Hrupec, D., Hughes, G., H??tten, M., Iarlori, M., Inada, T., Inoue, S., Insolia, A., Ionica, M., Iori, M., Jacquemont, M., Jamrozy, M., Janecek, P., Jim??nez Mart??nez, I., Jin, W., Jung-Richardt, I., Jurysek, J., Kaaret, P., Karas, V., Karkar, S., Kawanaka, N., Kerszberg, D., Kh??lifi, B., Kissmann, R., Kn??dlseder, J., Kobayashi, Y., Kohri, K., Komin, N., Kong, A., Kosack, K., Kubo, H., La Palombara, N., Lamanna, G., Lang, R. G., Lapington, J., Laporte, P., Lefaucheur, J., Lemoine-Goumard, M., Lenain, J., Leone, F., Leto, G., Leuschner, F., Lindfors, E., Lloyd, S., Lohse, T., Lombardi, S., Longo, F., Lopez, A., L??pez, M., L??pez-Coto, R., Loporchio, S., Lucarelli, F., Luque-Escamilla, P. L., Lyard, E., Maggio, C., Majczyna, A., Makariev, M., Mallamaci, M., Mandat, D., Maneva, G., Manganaro, M., Manic??, G., Marcowith, A., Marculewicz, M., Markoff, S., Marquez, P., Mart??, J., Martinez, O., Mart??nez, M., Mart??nez, G., Mart??nez-Huerta, H., Maurin, G., Mazin, D., Mbarubucyeye, J. D., Medina Miranda, D., Meyer, M., Micanovic, S., Miener, T., Minev, M., Miranda, J. M., Mitchell, A., Mizuno, T., Mode, B., Moderski, R., Mohrmann, L., Molina, E., Montaruli, T., Moralejo, A., Morales Merino, J., Morcuende-Parrilla, D., Morselli, A., Mukherjee, R., Mundell, C., Murach, T., Muraishi, H., Nagai, A., Nakamori, T., Nemmen, R., Niemiec, J., Nieto, D., Nievas, M., Nikolajuk, M., Nishijima, K., Noda, K., Nosek, D., Nozaki, S., O'Brien, P., Ohira, Y., Ohishi, M., Oka, T., Ong, R. A., Orienti, M., Orito, R., Orlandini, M., Orlando, E., Osborne, J. P., Ostrowski, M., Oya, I., Pagliaro, A., Palatka, M., Paneque, D., Pantaleo, F. R., Paredes, J. M., Parmiggiani, N., Patricelli, B., Pavleti??, L., Pe'Er, A., Pech, M., Pecimotika, M., Peresano, M., Persic, M., Petruk, O., Pfrang, K., Piatteli, P., Pietropaolo, E., Pillera, R., Pilszyk, B., Pimentel, D., Pintore, F., Pita, S., Pohl, M., Poireau, V., Polo, M., Prado, R. R., Prast, J., Principe, G., Produit, N., Prokoph, H., Prouza, M., Przybilski, H., Pueschel, E., P??hlhofer, G., Pumo, M. L., Punch, M., Queiroz, F., Quirrenbach, A., Rando, R., Razzaque, S., Rebert, E., Recchia, S., Reichherzer, P., Reimer, O., Reimer, A., Renier, Y., Reposeur, T., Rhode, W., Ribeiro, D., Rib??, M., Richtler, T., Rico, J., Rieger, F., Rizi, V., Rodriguez, J., Rodriguez Fernandez, G., Rodriguez Ramirez, J. C., Rodr??guez V??zquez, J. J., Romano, P., Romeo, G., Roncadelli, M., Rosado, J., Rosales de Leon, A., Rowell, G., Rudak, B., Rujopakarn, W., Russo, F., Sadeh, I., Saha, L., Saito, T., Salesa Greus, F., Sanchez, D., S??nchez-Conde, M., Sangiorgi, P., Sano, H., Santander, M., Santos, E. M., Sanuy, A., Sarkar, S., Saturni, F. G., Sawangwit, U., Scherer, A., Schleicher, B., Schovanek, P., Schussler, F., Schwanke, U., Sciacca, E., Scuderi, S., Seglar Arroyo, M., Sergijenko, O., Servillat, M., Seweryn, K., Shalchi, A., Sharma, P., Shellard, R. C., Siejkowski, H., Sinha, A., Sliusar, V., Slowikowska, A., Sokolenko, A., Sol, H., Specovius, A., Spencer, S., Spiga, D., Stamerra, A., Stani??, S., Starling, R., Stolarczyk, T., Straumann, U., Stri??kovi??, J., Suda, Y., wierk, P., Tagliaferri, G., Takahashi, H., Takahashi, M., Tavecchio, F., Taylor, L., Tejedor, L. A., Temnikov, P., Terrier, R., Terzic, T., Testa, V., Tian, W., Tibaldo, L., Tonev, D., Torres, D. F., Torresi, E., Tosti, L., Tothill, N., Tovmassian, G., Travnicek, P., Truzzi, S., Tuossenel, F., Umana, G., Vacula, M., Vagelli, V., Valentino, M., Vallage, B., Vallania, P., van Eldik, C., Varner, G. S., Vassiliev, V., V??zquez Acosta, M., Vecchi, M., Veh, J., Vercellone, S., Vergani, S., Verguilov, V., Vettolani, G. P., Viana, A., Vigorito, C. F., Vitale, V., Vorobiov, S., Vovk, I., Vuillaume, T., Wagner, S. J., Walter, R., Watson, J., White, M., White, R., Wiemann, R., Wierzcholska, A., Will, M., Williams, D. A., Wischnewski, R., Wolter, A., Yamazaki, R., Yanagita, S., Yang, L., Yoshikoshi, T., Zacharias, M., Zaharijas, G., Zaric, D., Zavrtanik, M., Zavrtanik, D., Zdziarski, A. A., Zech, A., Zechlin, H., Zhdanov, V. I., ivec, M., Comisión Nacional de Investigación Científica y Tecnológica (Chile), Ministry of Education, Youth and Sports (Czech Republic), Academy of Finland, Istituto Nazionale di Astrofisica, National Science Centre (Poland), Slovenian Research Agency, European Commission, Ministerio de Economía y Competitividad (España), Ministerio de Ciencia e Innovación (España), Junta de Andalucía, Astrophysique Interprétation Modélisation (AIM (UMR_7158 / UMR_E_9005 / UM_112)), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7), Laboratoire Leprince-Ringuet (LLR), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Univers et Particules de Montpellier (LUPM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Montpellier 2 - Sciences et Techniques (UM2), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire Univers et Théories (LUTH (UMR_8102)), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institut de recherche en astrophysique et planétologie (IRAP), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), Centre d'Etudes Nucléaires de Bordeaux Gradignan (CENBG), Université Sciences et Technologies - Bordeaux 1-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), CTA, UAM. Departamento de Física Teórica, Batista, R. A., Anguner, E. O., Ascasibar, Y., Larriva, A. B., Martins, V. B., De Almeida, U. B., Gonzalez, J. B., Tjus, J. B., Arbeletche, L. B., Bottcher, M., Angelis, A. D., De Lavergne, M. D. B., Caprio, V. D., De Dos Anjos, R. C., De Gouveia Dal Pino, E. M., Lotto, B. D., Martino, D. D., De Naurois, M., Wilhelmi, E. D. O., DE PALMA, F., De Souza, V., Ceca, R. D., Volpe, D. D., Girolamo, T. D., Pierro, F. D., Diaz, C., Diaz-Bahamondes, C., Djannati-Atai, A., Dominguez, A., Elsasser, D., Coromina, L. F., Gonzalez, J. M., Collado, T. H., Cadena, S. H., Horandel, J., Hutten, M., Martinez, I. J., Khelifi, B., Knodlseder, J., Palombara, N. L., Lopez, M., Lopez-Coto, R., Manico, G., Marti, J., Martinez, M., Martinez, G., Martinez-Huerta, H., Miranda, D. M., Merino, J. M., Pavletic, L., Puhlhofer, G., Ribo, M., Fernandez, G. R., Ramirez, J. C. R., Vazquez, J. J. R., De Leon, A. R., Greus, F. S., Sanchez-Conde, M., Arroyo, M. S., Stanic, S., Striskovic, J., Swierk, P., Eldik, C. V., Acosta, M. V., Zivec, M., Astrophysique Interprétation Modélisation (AIM (UMR7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Galaxies, Etoiles, Physique, Instrumentation (GEPI), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Université Sciences et Technologies - Bordeaux 1 (UB)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Abdalla H., Abe H., Acero F., Acharyya A., Adam R., Agudo I., Aguirre-Santaella A., Alfaro R., Alfaro J., Alispach C., Aloisio R., Batista R.A., Amati L., Amato E., Ambrosi G., Anguner E.O., Araudo A., Armstrong T., Arqueros F., Arrabito L., Asano K., Ascasibar Y., Ashley M., Backes M., Balazs C., Balbo M., Balmaverde B., Larriva A.B., Martins V.B., Barkov M., Baroncelli L., De Almeida U.B., Barrio J.A., Batista P.-I., Gonzalez J.B., Becherini Y., Beck G., Tjus J.B., Belmont R., Benbow W., Bernardini E., Berti A., Berton M., Bertucci B., Beshley V., Bi B., Biasuzzi B., Biland A., Bissaldi E., Biteau J., Blanch O., Bocchino F., Boisson C., Bolmont J., Bonanno G., Arbeletche L.B., Bonnoli G., Bordas P., Bottacini E., Bottcher M., Bozhilov V., Bregeon J., Brill A., Brown A.M., Bruno P., Bruno A., Bulgarelli A., Burton M., Buscemi M., Caccianiga A., Cameron R., Capasso M., Caprai M., Caproni A., Capuzzo-Dolcetta R., Caraveo P., Carosi R., Carosi A., Casanova S., Cascone E., Cauz D., Cerny K., Cerruti M., Chadwick P., Chaty S., Chen A., Chernyakova M., Chiaro G., Chiavassa A., Chytka L., Conforti V., Conte F., Contreras J.L., Coronado-Blazquez J., Cortina J., Costa A., Costantini H., Covino S., Cristofari P., Cuevas O., D'Ammando F., Daniel M.K., Davies J., Dazzi F., Angelis A.D., De Lavergne M.D.B., Caprio V.D., De Dos Anjos R.C., De Gouveia Dal Pino E.M., Lotto B.D., Martino D.D., De Naurois M., Wilhelmi E.D.O., Palma F.D., De Souza V., Delgado C., Ceca R.D., Volpe D.D., Depaoli D., Girolamo T.D., Pierro F.D., Diaz C., Diaz-Bahamondes C., Diebold S., Djannati-Atai A., Dmytriiev A., Dominguez A., Donini A., Dorner D., Doro M., Dournaux J., Dwarkadas V.V., Ebr J., Eckner C., Einecke S., Ekoume T.R.N., Elsasser D., Emery G., Evoli C., Fairbairn M., Falceta-Goncalves D., Fegan S., Feng Q., Ferrand G., Fiandrini E., Fiasson A., Fioretti V., Foffano L., Fonseca M.V., Font L., Fontaine G., Franco F.J., Coromina L.F., Fukami S., Fukazawa Y., Fukui Y., Gaggero D., Galanti G., Gammaldi V., Garcia E., Garczarczyk M., Gascon D., Gaug M., Gent A., Ghalumyan A., Ghirlanda G., Gianotti F., Giarrusso M., Giavitto G., Giglietto N., Giordano F., Glicenstein J., Goldoni P., Gonzalez J.M., Gourgouliatos K., Grabarczyk T., Grandi P., Granot J., Grasso D., Green J., Grube J., Gueta O., Gunji S., Halim A., Harvey M., Collado T.H., Hayashi K., Heller M., Cadena S.H., Hervet O., Hinton J., Hiroshima N., Hnatyk B., Hnatyk R., Hoffmann D., Hofmann W., Holder J., Horan D., Horandel J., Horvath P., Hovatta T., Hrabovsky M., Hrupec D., Hughes G., Hutten M., Iarlori M., Inada T., Inoue S., Insolia A., Ionica M., Iori M., Jacquemont M., Jamrozy M., Janecek P., Martinez I.J., Jin W., Jung-Richardt I., Jurysek J., Kaaret P., Karas V., Karkar S., Kawanaka N., Kerszberg D., Khelifi B., Kissmann R., Knodlseder J., Kobayashi Y., Kohri K., Komin N., Kong A., Kosack K., Kubo H., Palombara N.L., Lamanna G., Lang R.G., Lapington J., Laporte P., Lefaucheur J., Lemoine-Goumard M., Lenain J., Leone F., Leto G., Leuschner F., Lindfors E., Lloyd S., Lohse T., Lombardi S., Longo F., Lopez A., Lopez M., Lopez-Coto R., Loporchio S., Lucarelli F., Luque-Escamilla P.L., Lyard E., Maggio C., Majczyna A., Makariev M., Mallamaci M., Mandat D., Maneva G., Manganaro M., Manico G., Marcowith A., Marculewicz M., Markoff S., Marquez P., Marti J., Martinez O., Martinez M., Martinez G., Martinez-Huerta H., Maurin G., Mazin D., Mbarubucyeye J.D., Miranda D.M., Meyer M., Micanovic S., Miener T., Minev M., Miranda J.M., Mitchell A., Mizuno T., Mode B., Moderski R., Mohrmann L., Molina E., Montaruli T., Moralejo A., Merino J.M., Morcuende-Parrilla D., Morselli A., Mukherjee R., Mundell C., Murach T., Muraishi H., Nagai A., Nakamori T., Nemmen R., Niemiec J., Nieto D., Nievas M., Nikolajuk M., Nishijima K., Noda K., Nosek D., Nozaki S., O'Brien P., Ohira Y., Ohishi M., Oka T., Ong R.A., Orienti M., Orito R., Orlandini M., Orlando E., Osborne J.P., Ostrowski M., Oya I., Pagliaro A., Palatka M., Paneque D., Pantaleo F.R., Paredes J.M., Parmiggiani N., Patricelli B., Pavletic L., Pe'Er A., Pech M., Pecimotika M., Peresano M., Persic M., Petruk O., Pfrang K., Piatteli P., Pietropaolo E., Pillera R., Pilszyk B., Pimentel D., Pintore F., Pita S., Pohl M., Poireau V., Polo M., Prado R.R., Prast J., Principe G., Produit N., Prokoph H., Prouza M., Przybilski H., Pueschel E., Puhlhofer G., Pumo M.L., Punch M., Queiroz F., Quirrenbach A., Rando R., Razzaque S., Rebert E., Recchia S., Reichherzer P., Reimer O., Reimer A., Renier Y., Reposeur T., Rhode W., Ribeiro D., Ribo M., Richtler T., Rico J., Rieger F., Rizi V., Rodriguez J., Fernandez G.R., Ramirez J.C.R., Vazquez J.J.R., Romano P., Romeo G., Roncadelli M., Rosado J., De Leon A.R., Rowell G., Rudak B., Rujopakarn W., Russo F., Sadeh I., Saha L., Saito T., Greus F.S., Sanchez D., Sanchez-Conde M., Sangiorgi P., Sano H., Santander M., Santos E.M., Sanuy A., Sarkar S., Saturni F.G., Sawangwit U., Scherer A., Schleicher B., Schovanek P., Schussler F., Schwanke U., Sciacca E., Scuderi S., Arroyo M.S., Sergijenko O., Servillat M., Seweryn K., Shalchi A., Sharma P., Shellard R.C., Siejkowski H., Sinha A., Sliusar V., Slowikowska A., Sokolenko A., Sol H., Specovius A., Spencer S., Spiga D., Stamerra A., Stanic S., Starling R., Stolarczyk T., Straumann U., Striskovic J., Suda Y., Swierk P., Tagliaferri G., Takahashi H., Takahashi M., Tavecchio F., Taylor L., Tejedor L.A., Temnikov P., Terrier R., Terzic T., Testa V., Tian W., Tibaldo L., Tonev D., Torres D.F., Torresi E., Tosti L., Tothill N., Tovmassian G., Travnicek P., Truzzi S., Tuossenel F., Umana G., Vacula M., Vagelli V., Valentino M., Vallage B., Vallania P., Eldik C.V., Varner G.S., Vassiliev V., Acosta M.V., Vecchi M., Veh J., Vercellone S., Vergani S., Verguilov V., Vettolani G.P., Viana A., Vigorito C.F., Vitale V., Vorobiov S., Vovk I., Vuillaume T., Wagner S.J., Walter R., Watson J., White M., White R., Wiemann R., Wierzcholska A., Will M., Williams D.A., Wischnewski R., Wolter A., Yamazaki R., Yanagita S., Yang L., Yoshikoshi T., Zacharias M., Zaharijas G., Zaric D., Zavrtanik M., Zavrtanik D., Zdziarski A.A., Zech A., Zechlin H., Zhdanov V.I., Zivec M., ITA, USA, GBR, FRA, DEU, ESP, AUS, BRA, BGR, CHL, HRV, FIN, JPN, IRL, MEX, NAM, NLD, POL, CZE, SVN, SWE, CHE, UKR, Astronomy, High Energy Astrophys. & Astropart. Phys (API, FNWI), and Université Montpellier 2 - Sciences et Techniques (UM2)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Gamma ray Astronomy, Cherenkov Telescope Array, axions, MATÉRIA ESCURA, redshift: dependence, Astronomy, Gamma ray experiments, gamma ray experiments, Astrophysics, 01 natural sciences, Cosmology, Observatory, cosmological model: parameter space, gamma ray experiment, High Energy Astrophysical Phenomena (astro-ph.HE), astro-ph.HE, Physics, Cherenkov telescopes, IACT technique, Gamma rays, Cosmic rays, new physics, 4. Education, Settore FIS/01 - Fisica Sperimentale, Astrophysics::Instrumentation and Methods for Astrophysics, Gamma-ray astronomy, violation: Lorentz, 3. Good health, observatory, Extragalactic background light, astro-ph.CO, axion-like particles, Física nuclear, Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Cosmology and Nongalactic Astrophysics, gamma ray: propagation, Cosmology and Nongalactic Astrophysics (astro-ph.CO), Active galactic nucleus, Axions, Astrophysics::High Energy Astrophysical Phenomena, Dark matter, FOS: Physical sciences, Astrophysics::Cosmology and Extragalactic Astrophysics, invariance: Lorentz, jet: relativistic, dark matter: halo, 0103 physical sciences, active galactic nuclei, extragalactic magnetic fields, AGN, Blazar, background, 010308 nuclear & particles physics, Física, Astronomy and Astrophysics, sensitivity, axion, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], absorption, statistical, Blazars, Telescopes
Abstract

Full list of authors: Abdalla, H.; Abe, H.; Acero, F.; Acharyya, A.; Adam, R.; Agudo, I; Aguirre-Santaella, A.; Alfaro, R.; Alfaro, J.; Alispach, C.; Aloisio, R.; Batista, R. Alves; Amati, L.; Amato, E.; Ambrosi, G.; Anguner, E. O.; Araudo, A.; Armstrong, T.; Arqueros, F.; Arrabito, L.; Asano, K.; Ascasibar, Y.; Ashley, M.; Backes, M.; Balazs, C.; Balbo, M.; Balmaverde, B.; Baquero Larriva, A.; Martins, V. Barbosa; Barkov, M.; Baroncelli, L.; de Almeida, U. Barres; Barrio, J. A.; Batista, P-, I; Becerra Gonzalez, J.; Becherini, Y.; Beck, G.; Tjus, J. Becker; Belmont, R.; Benbow, W.; Bernardini, E.; Berti, A.; Berton, M.; Bertucci, B.; Beshley, V; Bi, B.; Biasuzzi, B.; Biland, A.; Bissaldi, E.; Biteau, J.; Blanch, O.; Bocchino, F.; Boisson, C.; Bolmont, J.; Bonanno, G.; Arbeletche, L. Bonneau; Bonnoli, G.; Bordas, P.; Bottacini, E.; Bottcher, M.; Bozhilov, V; Bregeon, J.; Brill, A.; Brown, A. M.; Bruno, P.; Bruno, A.; Bulgarelli, A.; Burton, M.; Buscemi, M.; Caccianiga, A.; Cameron, R.; Capasso, M.; Caprai, M.; Caproni, A.; Capuzzo-Dolcetta, R.; Caraveo, P.; Carosi, R.; Carosi, A.; Casanova, S.; Cascone, E.; Cauz, D.; Cerny, K.; Cerruti, M.; Chadwick, P.; Chaty, S.; Chen, A.; Chernyakova, M.; Chiaro, G.; Chiavassa, A.; Chytka, L.; Conforti, V; Conte, F.; Contreras, J. L.; Coronado-Blazquez, J.; Cortina, J.; Costa, A.; Costantini, H.; Covino, S.; Cristofari, P.; Cuevas, O.; D'Ammando, F.; Daniel, M. K.; Davies, J.; Dazzi, F.; De Angelis, A.; de Lavergne, M. de Bony; De Caprio, V; dos Anjos, R. de Cassia; Dal Pino, E. M. de Gouveia; De Lotto, B.; De Martino, D.; de Naurois, M.; Wilhelmi, E. de Ona; De Palma, F.; de Souza, V; Delgado, C.; Della Ceca, R.; della Volpe, D.; Depaoli, D.; Di Girolamo, T.; Di Pierro, F.; Diaz, C.; Diaz-Bahamondes, C.; Diebold, S.; Djannati-Atai, A.; Dmytriiev, A.; Dominguez, A.; Donini, A.; Dorner, D.; Doro, M.; Dournaux, J.; Dwarkadas, V. V.; Ebr, J.; Eckner, C.; Einecke, S.; Ekoume, T. R. N.; Elsaesser, D.; Emery, G.; Evoli, C.; Fairbairn, M.; Falceta-Goncalves, D.; Fegan, S.; Feng, Q.; Ferrand, G.; Fiandrini, E.; Fiasson, A.; Fioretti, V; Foffano, L.; Fonseca, M., V; Font, L.; Fontaine, G.; Franco, F. J.; Freixas Coromina, L.; Fukami, S.; Fukazawa, Y.; Fukui, Y.; Gaggero, D.; Galanti, G.; Gammaldi, V; Garcia, E.; Garczarczyk, M.; Gascon, D.; Gaug, M.; Gent, A.; Ghalumyan, A.; Ghirlanda, G.; Gianotti, F.; Giarrusso, M.; Giavitto, G.; Giglietto, N.; Giordano, F.; Glicenstein, J.; Goldoni, P.; Gonzalez, J. M.; Gourgouliatos, K.; Grabarczyk, T.; Grandi, P.; Granot, J.; Grasso, D.; Green, J.; Grube, J.; Gueta, O.; Gunji, S.; Halim, A.; Harvey, M.; Collado, T. Hassan; Hayashi, K.; Heller, M.; Cadena, S. Hernandez; Hervet, O.; Hinton, J.; Hiroshima, N.; Hnatyk, B.; Hnatyk, R.; Hoffmann, D.; Hofmann, W.; Holder, J.; Horan, D.; Horandel, J.; Horvath, P.; Hovatta, T.; Hrabovsky, M.; Hrupec, D.; Hughes, G.; Hutten, M.; Iarlori, M.; Inada, T.; Inoue, S.; Insolia, A.; Ionica, M.; Iori, M.; Jacquemont, M.; Jamrozy, M.; Janecek, P.; Jimenez Martinez, I; Jin, W.; Jung-Richardt, I; Jurysek, J.; Kaaret, P.; Karas, V; Karkar, S.; Kawanaka, N.; Kerszberg, D.; Khelifi, B.; Kissmann, R.; Knodlseder, J.; Kobayashi, Y.; Kohri, K.; Komin, N.; Kong, A.; Kosack, K.; Kubo, H.; La Palombara, N.; Lamanna, G.; Lang, R. G.; Lapington, J.; Laporte, P.; Lefaucheur, J.; Lemoine-Goumard, M.; Lenain, J.; Leone, F.; Leto, G.; Leuschner, F.; Lindfors, E.; Lloyd, S.; Lohse, T.; Lombardi, S.; Longo, F.; Lopez, A.; Lopez, M.; Lopez-Coto, R.; Loporchio, S.; Lucarelli, F.; Luque-Escamilla, P. L.; Lyard, E.; Maggio, C.; Majczyna, A.; Makariev, M.; Mallamaci, M.; Mandat, D.; Maneva, G.; Manganaro, M.; Manico, G.; Marcowith, A.; Marculewicz, M.; Markoff, S.; Marquez, P.; Marti, J.; Martinez, O.; Martinez, M.; Martinez, G.; Martinez-Huerta, H.; Maurin, G.; Mazin, D.; Mbarubucyeye, J. D.; Miranda, D. Medina; Meyer, M.; Micanovic, S.; Miener, T.; Minev, M.; Miranda, J. M.; Mitchell, A.; Mizuno, T.; Mode, B.; Moderski, R.; Mohrmann, L.; Molina, E.; Montaruli, T.; Moralejo, A.; Morales Merino, J.; Morcuende-Parrilla, D.; Morselli, A.; Mukherjee, R.; Mundell, C.; Murach, T.; Muraishi, H.; Nagai, A.; Nakamori, T.; Nemmen, R.; Niemiec, J.; Nieto, D.; Nievas, M.; Nikolajuk, M.; Nishijima, K.; Noda, K.; Nosek, D.; Nozaki, S.; Ohira, Y.; Ohishi, M.; Oka, T.; Ong, R. A.; Orienti, M.; Orito, R.; Orlandini, M.; Orlando, E.; Osborne, J. P.; Ostrowski, M.; Oya, I; Pagliaro, A.; Palatka, M.; Paneque, D.; Pantaleo, F. R.; Paredes, J. M.; Parmiggiani, N.; Patricelli, B.; Pavletic, L.; Pe'er, A.; Pech, M.; Pecimotika, M.; Peresano, M.; Persic, M.; Petruk, O.; Pfrang, K.; Piatteli, P.; Pietropaolo, E.; Pillera, R.; Pilszyk, B.; Pimentel, D.; Pintore, F.; Pita, S.; Pohl, M.; Poireau, V; Polo, M.; Prado, R. R.; Prast, J.; Principe, G.; Produit, N.; Prokoph, H.; Prouza, M.; Przybilski, H.; Pueschel, E.; Puehlhofer, G.; Pumo, M. L.; Punch, M.; Queiroz, F.; Quirrenbach, A.; Rando, R.; Razzaque, S.; Rebert, E.; Recchia, S.; Reichherzer, P.; Reimer, O.; Reimer, A.; Renier, Y.; Reposeur, T.; Rhode, W.; Ribeiro, D.; Ribo, M.; Richtler, T.; Rico, J.; Rieger, F.; Rizi, V; Rodriguez, J.; Fernandez, G. Rodriguez; Ramirez, J. C. Rodriguez; Rodriguez Vazquez, J. J.; Romano, P.; Romeo, G.; Roncadelli, M.; Rosado, J.; de Leon, A. Rosales; Rowell, G.; Rudak, B.; Rujopakarn, W.; Russo, F.; Sadeh, I; Saha, L.; Saito, T.; Greus, F. Salesa; Sanchez, D.; Sanchez-Conde, M.; Sangiorgi, P.; Sano, H.; Santander, M.; Santos, E. M.; Sanuy, A.; Sarkar, S.; Saturni, F. G.; Sawangwit, U.; Scherer, A.; Schleicher, B.; Schovanek, P.; Schussler, F.; Schwanke, U.; Sciacca, E.; Scuderi, S.; Arroyo, M. Seglar; Sergijenko, O.; Servillat, M.; Seweryn, K.; Shalchi, A.; Sharma, P.; Shellard, R. C.; Siejkowski, H.; Sinha, A.; Sliusar, V; Slowikowska, A.; Sokolenko, A.; Sol, H.; Specovius, A.; Spencer, S.; Spiga, D.; Stamerra, A.; Starling, R.; Stolarczyk, T.; Straumann, U.; Striskovic, J.; Suda, Y.; Tagliaferri, G.; Takahashi, H.; Takahashi, M.; Tavecchio, F.; Taylor, L.; Tejedor, L. A.; Temnikov, P.; Terrier, R.; Terzic, T.; Testa, V; Tian, W.; Tibaldo, L.; Tonev, D.; Torres, D. F.; Torresi, E.; Tosti, L.; Tothill, N.; Tovmassian, G.; Travnicek, P.; Truzzi, S.; Tuossenel, F.; Umana, G.; Vacula, M.; Vagelli, V.; Valentino, M.; Vallage, B.; Vallania, P.; van Eldik, C.; Varner, G. S.; Vassiliev, V.; Vazquez Acosta, M.; Vecchi, M.; Veh, J.; Vercellone, S.; Vergani, S.; Verguilov, V.; Vettolani, G. P.; Viana, A.; Vigorito, C. F.; Vitale, V.; Vorobiov, S.; Vovk, I; Vuillaume, T.; Wagner, S. J.; Walter, R.; Watson, J.; White, M.; White, R.; Wiemann, R.; Wierzcholska, A.; Will, M.; Williams, D. A.; Wischnewski, R.; Wolter, A.; Yamazaki, R.; Yanagita, S.; Yang, L.; Yoshikoshi, T.; Zacharias, M.; Zaharijas, G.; Zaric, D.; Zavrtanik, M.; Zavrtanik, D.; Zdziarski, A. A.; Zech, A.; Zechlin, H.; Zhdanov, V., I; Zivec, M., The Cherenkov Telescope Array (CTA), the new-generation ground-based observatory for γ astronomy, provides unique capabilities to address significant open questions in astrophysics, cosmology, and fundamental physics. We study some of the salient areas of γ cosmology that can be explored as part of the Key Science Projects of CTA, through simulated observations of active galactic nuclei (AGN) and of their relativistic jets. Observations of AGN with CTA will enable a measurement of γ absorption on the extragalactic background light with a statistical uncertainty below 15% up to a redshift z=2 and to constrain or detect γ halos up to intergalactic-magnetic-field strengths of at least 0.3 pG . Extragalactic observations with CTA also show promising potential to probe physics beyond the Standard Model. The best limits on Lorentz invariance violation from γ astronomy will be improved by a factor of at least two to three. CTA will also probe the parameter space in which axion-like particles could constitute a significant fraction, if not all, of dark matter. We conclude on the synergies between CTA and other upcoming facilities that will foster the growth of γ cosmology. © 2021 IOP Publishing Ltd and Sissa Medialab., We gratefully acknowledge financial support from the following agencies and organizations: State Committee of Science of Armenia, Armenia; The Australian Research Council, Astronomy Australia Ltd, The University of Adelaide, Australian National University, Monash University, The University of New South Wales, The University of Sydney, Western Sydney University, Australia; Federal Ministry of Education, Science and Research, and Innsbruck University, Austria; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ), Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), Ministry of Science, Technology, Innovations and Communications (MCTIC), Brasil; Ministry of Education and Science, National RI Roadmap Project DO1-153/28.08.2018, Bulgaria; The Natural Sciences and Engineering Research Council of Canada and the Canadian Space Agency, Canada; CONICYT-Chile grants CATA AFB 170002, ANID PIA/APOYO AFB 180002, ACT 1406, FONDECYT-Chile grants, 1161463, 1170171, 1190886, 1171421, 1170345, 1201582, Gemini-ANID 32180007, Chile; Croatian Science Foundation, Rudjer Boskovic Institute, University of Osijek, University of Rijeka, University of Split, Faculty of Electrical Engineering, Mechanical Engineering and Naval Architecture, University of Zagreb, Faculty of Electrical Engineering and Computing, Croa tia; Ministry of Education, Youth and Sports, MEYS M2015046, LM2018105, LTT17006, EU/MEYS CZ.02.1.01/0.0/0.0/16_013/0001403, CZ.02.1.01/0.0/0.0/18_046/0016007 and CZ.02.1.01/0.0/0.0/16_019/0000754, Czech Republic; Academy of Finland (grant nr.317636 and 320045), Finland; Ministry of Higher Education and Research, CNRS-INSU and CNRS-IN2P3, CEA-Irfu, ANR, Regional Council Ile de France, Labex ENIGMASS, OCEVU, OSUG2020 and P2IO, France; Max Planck Society, BMBF, DESY, Helmholtz Association, Germany; Department of Atomic Energy, Department of Science and Technology, India; Istituto Nazionale di Astrofisica (INAF), Istituto Nazionale di Fisica Nucleare (INFN), MIUR, Istituto Nazionale di Astrofisica (INAF-OABRERA) Grant Fondazione Cariplo/Regione Lombardia ID 2014-1980/RST_ERC, Italy; ICRR, University of Tokyo, JSPS, MEXT, Japan; Netherlands Research School for Astronomy (NOVA), Netherlands Organization for Scientific Research (NWO), Netherlands; University of Oslo, Norway; Ministry of Science and Higher Education, DIR/WK/2017/12, the National Centre for Research and Development and the National Science Centre, UMO-2016/22/M/ST9/00583, Poland; Slovenian Research Agency, grants P1-0031, P1-0385, I0-0033, J1-9146, J1-1700, N1-0111, and the Young Researcher program, Slovenia; South African Department of Science and Technology and National Research Foundation through the South African Gamma-Ray Astronomy Programme, South Africa; The Spanish groups acknowledge the Spanish Ministry of Science and Innovation and the Spanish Research State Agency (AEI) through grants AYA2016-79724-C4-1-P, AYA2016-80889-P, AYA2016-76012-C3-1-P, BES-2016-076342, FPA2017-82729-C6-1-R, FPA2017-82729-C6-2-R, FPA2017-82729-C6-3-R, FPA2017-82729-C6-4-R, FPA2017-82729-C6-5-R, FPA2017-82729-C6-6-R, PGC2018-095161-B-I00, PGC2018-095512-B-I00, PID2019-107988GB-C22; the “Centro de Excelencia Severo Ochoa” program through grants no. SEV-2016-0597, SEV-2016-0588, SEV-2017-0709, CEX2019-000920-S; the “Unidad de Excelencia María de Maeztu” program through grant no. MDM-2015-0509; the “Ramón y Cajal” programme through grants RYC-2013-14511, RYC-2017-22665; and the MultiDark Consolider Network FPA2017-90566-REDC. They also acknowledge the Atracción de Talento contract no. 2016-T1/TIC-1542 granted by the Comunidad de Madrid; the “Postdoctoral Junior Leader Fellowship” programme from La Caixa Bank ing Foundation, grants no. LCF/BQ/LI18/11630014 and LCF/BQ/PI18/11630012; the “Programa Operativo” FEDER 2014-2020, Consejería de Economía y Conocimiento de la Junta de Andalucía (Ref. 1257737), PAIDI 2020 (Ref. P18-FR-1580) and Universidad de Jaén; “Programa Operativo de Crecimiento Inteligente” FEDER 2014-2020 (Ref. ESFRI-2017-IAC-12), Ministerio de Ciencia e Innovación, 15% co-financed by Consejería de Economía, Industria, Comercio y Conocimiento del Gobierno de Canarias; the Spanish AEI EQC2018-005094-P FEDER 2014-2020; the European Union’s “Horizon 2020” research and innovation programme under Marie Skłodowska-Curie grant agreement no. 665919; and the ESCAPE project with grant no. GA:824064; Swedish Research Council, Royal Physiographic Society of Lund, Royal Swedish Academy of Sciences, The Swedish National Infrastructure for Computing (SNIC) at Lunarc (Lund), Sweden; State Secretariat for Education, Research and Innovation (SERI) and Swiss National Science Foundation (SNSF), Switzerland; Durham University, Leverhulme Trust, Liverpool University, University of Leicester, University of Oxford, Royal Soci ety, Science and Technology Facilities Council, UK; U.S. National Science Foundation, U.S. Department of Energy, Argonne National Laboratory, Barnard College, University of California, University of Chicago, Columbia University, Georgia Institute of Technology, Institute for Nuclear and Particle Astrophysics (INPAC-MRPI program), Iowa State University, the Smithsonian Institution, Washington University McDonnell Center for the Space Sciences, The University of Wisconsin and the Wisconsin Alumni Research Foundation, USA. The research leading to these results has received funding from the European Union’s Seventh Framework Programme (FP7/2007-2013) under grant agreements No 262053 and No 317446. This project is receiving funding from the European Union’s Horizon 2020 research and innovation programs under agreement No 676134. The research leading to these results has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement GammaRayCascades No 843800. The Fermi LAT Collaboration acknowledges generous ongoing support from a number of agencies and institutes that have supported both the development and the operation of the LAT as well as scientific data analysis. These include the National Aeronautics and Space Administration and the Department of Energy in the United States, the Commissariat à l’Energie Atomique and the Centre National de la Recherche Scientifique / Institut National de Physique Nucléaire et de Physique des Particules in France, the Agenzia Spaziale Italiana and the Istituto Nazionale di Fisica Nucleare in Italy, the Ministry of Education, Culture, Sports, Science and Technology (MEXT), High Energy Accelerator Research Organization (KEK) and Japan Aerospace Exploration Agency (JAXA) in Japan, and the K. A. Wallenberg Foundation, the Swedish Research Council and the Swedish National Space Board in Sweden. Additional support for science analysis during the operations phase is gratefully acknowledged from the Istituto Nazionale di Astrofisica in Italy and the Centre National d’Études Spatiales in France. This work performed in part under DOE Contract DE-AC02-76SF00515.

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results