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Since 2015/16 the DGPRÄC collects, evaluates and publishes the research activities of academic sections, departments and clinics for plastic surgery at university hospitals in Germany, in order to raise the awareness of plastic surgical research performance. The directors of plastic surgical academic institutions were contacted via the DGPRÄC and asked to report any requested/approved and rejected research applications to public, non-public and industrial funding organizations. Data was collected in our previously established online database: https://docs.google.com/forms/d/e/1FAIpQLSe6F5xmTyw-k7VKJx_2jkPA4LBXsA0sgBGMrC3rx_4bHj6uzQ/viewform?usp=sf_link. In addition, applications were identified via the DFG's public database GEPRIS. A total of 41 funding applications to the public funding institutes DFG, BMBF, BMWi, BMG and EU were identified. 75.6 % (31/41) of the applications had already been approved at the time of data collection, of which 77.4 % (24/31) were DFG, 9.7 % (3/31) were BMWi, 6.5 % (2/31) were EU and 3.2 % (1/31) were BMBF or BMG applications. The average funding amounted to 358 301 Euro. In 50.0 % (12/24) of the cases, the approved DFG proposals were assigned to the subject review board 205-27 Orthopedics, Trauma Surgery, Reconstructive Surgery. The continuous publication of plastic surgical research funding reports submitted by the convention of university plastic surgeons of the DGPRÄC portraits the excellent, collaborative research activity in the field of plastic surgery. Seit 2015/16 werden Forschungsanträge aus Sektionen, Abteilungen und Kliniken für Plastische Chirurgie an den Universitätskliniken Deutschlands durch die Deutsche Gesellschaft der Plastischen, Rekonstruktiven und Ästhetischen Chirurgen (DGPRÄC) gesammelt, ausgewertet und 2-jährlich veröffentlicht. Ziel ist es, dadurch die Forschungsleistung der Plastischen Chirurgen in Deutschland öffentlich sichtbar zu machen, um eine Stärkung der akademischen Forschungsstruktur in Deutschland zu erreichen. Die Leiter der universitären Einrichtungen wurden über den Verteiler der DGPRÄC kontaktiert und um Mitteilung der beantragten, in Begutachtung befindlichen, abgelehnten und geförderten Projekte jeglicher öffentlicher, nicht-öffentlicher, industrieller oder anderer Förderinstitute in die eigens dafür erstellte online Datenbank gebeten: https://docs.google.com/forms/d/e/1FAIpQLSe6F5xmTyw-k7VKJx_2jkPA4LBXsA0sgBGMrC3rx_4bHj6uzQ/viewform?usp=sf_link. Zusätzlich wurden Anträge über die öffentliche Datenbank der Deutschen Forschungsgemeinschaft (DFG), dem Geförderte Projekte Informationssystem (GEPRIS), identifiziert. Eine Gesamtzahl von 41 Förderanträgen aus den öffentlichen Förderinstituten DFG, BMBF, BMWi, BMG und EU konnte identifiziert werden. 75,6 % (31/41) der Anträge waren zum Zeitpunkt der Datenerhebung bereits bewilligt, davon waren 77,4 % (24/31) DFG-, 9,7 % (3/31) BMWi-, 6,5 % (2/31) EU- und je 3,2 % (1/31) BMBF- und BMG-Anträge. Das durchschnittliche Fördervolumen entsprach 358 301 Euro. Die bewilligten DFG-Anträge waren in 50,0 % (12/24) der Fälle ausschließlich bzw. unter anderem dem Fachkollegium 205–27 Orthopädie, Unfallchirurgie, rekonstruktive Chirurgie zugeordnet. Mithilfe der vorgelegten Forschungsförderungsberichte des Konvents der leitenden universitär tätigen Plastischen Chirurgen der DGPRÄC erfolgt die Veröffentlichung der exzellenten gemeinschaftlichen akademischen Forschungsleistung in unserem Fachgebiet.

Severe infections frequently cause large soft tissue defects which require early defect coverage by plastic surgeons. A number of reconstructive treatment options are available, ranging from local flaps to microvascular free flap reconstructions. In this respect it is important that the selection of the optimal reconstructive technique is made based on individual patient characteristics and in a timely manner. Weeks of inpatient treatment with vacuum dressings often delay defect coverage and should be avoided as they burden both the patient and the healthcare system. Therefore, it is in the best interest of patients to receive early treatment by plastic surgeons. This manuscript presents the essential reconstructive treatment approaches based on highly informative case reports of patients from the plastic surgical practice at a university hospital.

Artificial intelligence (AI) has long been established in various parts of everyday life due to the instrumentalization of machines and robotics in industry, autonomous vehicles and the rapid development of computer-based systems.Demonstration of current developments and perspectives of AI in plastic surgery.Evaluation of statistics, press releases and original articles from journals and discussion of reviews.In the healthcare system and in plastic surgery AI is particularly useful in the context of data analysis from digital patient files and big data from central registers. The use of 3D imaging systems provides objective feedback on surgical results in terms of volume and aesthetics. Intelligent robots assist plastic surgeons in microsurgical anastomoses of increasingly smaller vessels and the implementation of AI in the field of prosthetics enables patients to regain hand function following amputation injuries.For the benefit of the patients, it is the responsibility of experimental surgery to explore the opportunities, risks and limitations of applications with AI.

As a plastic surgeon you grow up in the community of surgeons of all specialties. You develop an awareness that the field of plastic surgery is an integral part of surgery. You strongly believe that the surgical specialties have built a strong community of solidarity among each other – the unity of surgery.

This report serves to publicize the research of academic institutions for Plastic Surgery within our society DGPRÄC in 2017/2018 and sequels the funding report of 2015/2016. Applications to public, non-public, or industrial funding organizations were evaluated. At the same time, this paper analyses the number of approved DFG applications in Plastic, Thoracic and Vascular Surgery in the GEPRIS system. Contrary to these specialties, Plastic Surgery is not classified as an independent speciality in the subject structure of the DFG review board which results in a lack of transparency concerning Plastic Surgery research work.Our previously established online database (https://docs.google.com/forms/d/1OaSnHyKTysawiI1ie7kfUxDf7nJP_RiTUJTsnb7Mq_E/edit) for reporting requested/ approved and rejected research applications to public, non-public and industrial funding organizations was continued and evaluated together with applications found in the DFG's public database GEPRIS.Compared to the previous year's report, the number of approved applications from public research organizations (DFG, BMBF, BMWi, EU) was increased from 23 to 27. We identified 19 approved DFG applications from Plastic Surgery, as compared to 9 and 8 applications by Thoracic and Vascular Surgery, respectively.Taken together, this data emphasizes that our research is at least equal to that of other newly established surgical specialties within the framework of the DFG. Accordingly, we hope to provide further arguments for an adaptation of the DFG review boards subject structure to include Plastic Surgery as an independent specialty as it is for Vascular Surgery and Thoracic Surgery.Dieser Bericht baut auf dem Forschungsförderungsbericht aus dem Jahr 2015/2016 auf und dient der Bekanntmachung der akademischen Forschungsleistung an Universitätskliniken der Deutschen Gesellschaft der Plastischen, Rekonstruktiven und Ästhetischen Chirurgen (DGPRÄC) für 2017/2018. Berücksichtigt wurden dabei Anträge auf Forschungsförderung bei öffentlichen, nicht-öffentlichen, oder industriellen Förderinstituten. Gleichzeitig soll dieser Beitrag die Anzahl der genehmigten Anträge bei der Deutschen Forschungsgemeinschaft (DFG) aus der Plastischen Chirurgie, Thorax- und Gefäßchirurgie gegenüberstellen. Innerhalb dieser jüngeren selbständigen chirurgischen Fachgebiete wird das seit 1993 eigenständige Fachgebiet Plastische Chirurgie in der Fächerstruktur der DFG Fachkollegien immer noch nicht separat geführt, sondern dem Fachkollegium Orthopädie und Unfallchirurgie zugeordnet. Dies führt dazu, dass die Anträge nicht fachspezifisch begutachtet werden.Die bereits etablierte online Datenbank (https://docs.google.com/forms/d/1OaSnHyKTysawiI1ie7kfUxDf7nJP_RiTUJTsnb7Mq_E/edit) zur Meldung beantragter/ genehmigter und abgelehnter Forschungsförderungen öffentlicher, nicht-öffentlicher und industrieller Förderinstitutionen wurde fortgeführt und gemeinsam mit den Anträgen aus der öffentlichen Datenbank der DFG, das Geförderte Projekte Informationssystem (GEPRIS), ausgewertet.Im Vergleich zum letzten Beobachtungszeitraum von 2015/2016 nahm die Anzahl genehmigter Anträge aus öffentlichen Einrichtungen (DFG, BMBF, BMWi, EU) von 23 auf 27 zu. Aus den chirurgischen Fachgebieten Thorax- und Gefäßchirurgie waren jeweils 9 bzw. 8 DFG Anträge im GEPRIS dokumentiert, wohingegen 19 Bewilligungen von Anträgen der Plastischen Chirurgie identifiziert wurden.Durch die vorliegende Auswertung konnten wir zeigen, dass das Aufkommen an Anträgen aus dem Fachgebiet der Plastischen Chirurgie denen der anderen eigenständig geführten Fachgebiete entspricht, wobei sogar eine höhere Anzahl zu verzeichnen ist. Vor diesem Hintergrund ist die gegenwärtige Subsummierung seitens der DFG, auch im Hinblick auf eine öffentlich nachvollziehbare Vergabe der Fördersummen, nicht zu akzeptieren.

Einleitung: Therapie der Wahl von Weichteil-Sarkomen ist bei geeigneten Patienten das gliedmasen-erhaltende Vorgehen. Schlusselrolle hat die geforderte chirurgische R0-Resektion. 5-Jahres-Uberlebensraten sind heute in spezialisierten Zentren mit interdisziplinareren Tumorboards vielversprechend. Problemstellung: Hierdurch gewinnen die Extremitatenfunktion und Lebensqualitat und damit auch die sekundare Defektdeckung mit anatomischer, autologer Rekonstruktion an Bedeutung. Anatomische Rekonstruktion und Wahl der Lappenplastik konnen das funktionelle Ergebnis entscheidend beeinflussen. Ziel der Arbeit: Die Arbeit befasst sich mit Anwendungsmoglichkeiten der mikrovaskularen M. gracilis-Lappenplastik zur Defektdeckung und anatomischen Rekonstruktion nach gliedmasen-erhaltender Weichteil-Sarkom-Resektion an Hand und Fus. Patienten und Methode: Im Zeitraum 2012–2014, mittlerer Beobachtungzeitraum 444 Tage (98–820), wurde bei insgesamt 8 Patienten (weiblich N=4), Durchschnittsalter 49 Jahre (23–76) nach gliedmasen-erhaltender Tumor-Resektion (Leiomyosarkom N=2, Myxofibrosarkom N=2, Klarzell-Sarkom N=1, myxoinflammatorisches fibroblastisches Sarkom N=1, Granularzelltumor N=1, pleomorphes Sarkom N=1) an Hand und Fus (N=7) die mikrovaskulare Defektdeckung und anatomische Rekonstruktion mit M. gracilis-Lappenplastik/Hauttransplantaten durchgefuhrt. Ergebnisse: Bei Allen wurde eine erfolgreiche Defekt-Deckung ohne operationspflichtige Wundheilungsstorungen (adjuvante Radiatio N=4) erzielt. Erganzend erfolgte die anatomische Rekonstruktion der folgenden aus onkologischen Grunden resezierten anatomischen Strukturen unter Verwendung der M. gracilils Sehne: Retinaculum extensorum N=1, Beuge-/Strecksehne N=4, Streckerhaube N=2, Sehnen-Reinsertion N=1, Lig. collaterale Grundgelenk N=4, Lig. metatarsale transversum profundum N=1, Lig. metacarpale transversum profundum N=1. Im Beoachtungszeitraum ergaben sich keine Hinweise auf Lokalrezidive oder metastatische Ausbreitung. Schlussfolgerung: Neben Defektdeckung unter Berucksichtigung von Sensibilitat bzw. Weichteil-Stabilitat, Totraum-Obliteration und Prophylaxe strahleninduzierter Wundheilungsstorungen soll das Ziel auch die Rekonstruktion multidirektionaler Stabilitat und komplexer Biomechanik/-kinetik an Hand und Fus sein. Die M. gracilis-Lappenplastik ist unsere erste Wahl zur anatomischen Rekonstruktion nach gliedmasen-erhaltender Sarkom Resektion in Arealen wo epikritische Sensibilitat untergeordnet ist.

Since the introduction of silicone implants, several events have led to considerable uncertainty among the patients, public, and users. So far, however, the necessary steps to significantly improving patient safety have not been taken in any of these cases. Requiring stricter approvals for medical devices, improving monitoring by the regulatory authorities and the revision of the Medical Devices Directive are all initial steps in the right direction towards a change in policy, but are insufficient as an early warning system. After the introduction of registers was announced in the coalition agreement, the German Society of Plastic, Aesthetic and Reconstructive Surgeons (DGPRÄC), in close consultation with the Ministry of Health, has developed a concept which is presented here. The need for a uniform and legally binding central register for breast implants is fully supported by the entire medical profession. According to the concept presented by the DGPRÄC, three data qualities would be applicable: Safety data (mandatory), physician information (voluntary) and research data (optional, except if safety related). The public authorities are creating a unified, secure entry portal for all professional associations concerned. This register is based with the professional associations, and from there the mandatory security data will be forwarded to the public authorities. Decoding of the identity of the patient and doctor would only occur in specifically defined emergency situations such as product recalls. Automated tools in the security database provide early detection of problems, so that rapid clarification is possible in consultation with the professional associations, manufacturers and possibly patients. This concept as proposed by the DGPRÄC has thus far been very positively received in all discussions between the various parties concerned.

In addition to the impact factor, research funding also plays a central role in evaluating the academic performance and quality of a researcher, a clinic or a surgical specialty. The scope and quality of research in Plastic Surgery are usually very little known, so that even large funding institutions do not get a full view of research funding in our specialty. Therefore, sometimes traditional structures are not adapted to new needs by the developing younger surgical fields. In peer review sometimes peers are not chosen from the same surgical specialty, but from a different surgical fields being peers in large field of surgery. By this a bias can easily be generated which would not be advantageous for subspecialties such Plastic Surgery. The goal of this paper is to establish an overview in the form of a registry of the German Society of Plastic Reconstructive and Aesthetic Surgeons (DGPRÄC) in order to make the joint academic achievements more visible in the future. At the same time, a research funding report is to be published for the years 2015 and 2016.

On occasion of the Munich Plastic Symposium in Munich the board of the Deutsche Gesellschaft der Plastischen, Rekonstruktiven und Ästhetischen Chirurgen (DGPRÄC) together with a group of experts who were also involved in the preparation of the recently published S2K guideline "Autologous Fat Grafting", prepared a consensus statement from a plastic-surgical point of view so to evaluate current spects and taking into account the current legal framework: 1. Autologous Fat Grafting is a long established treatment in plastic surgery and does not differ from other tissue grafts. 2. Mechanical processing of autologous fat does not provide any substantial change tot he tissue. 3. If other treatment methods to enrich progenitor cells of autolous fat i. e. by an enzymatic process have evidence that autologous adipose tissue or cells were substantially changed, classification as a drug could come in question under current german law (application of AMG/ATMP).

There has been ongoing development in the field of 3-dimensional (3-D) Surface Imaging by laser scanner and digital 3-D photography (Photogrammetry) in recent years. Manufacturers tend to make new 3-D cameras compact, light-weighted, mobile, and user-friendly, similar to the development on the smartphone market. Although 3D scans have been used for patient consultations and digital documentation in Plastic Surgery since the 1980, there has been no significant development lately regarding its use for objective assistance during surgery.Our research team presents a new intraoperative 3-D scanning method for plastic-surgical procedures with selected mobile 3-D scanner systems. In the future, these might assist surgeons with the pre-, post-, and intraoperative 3-D analysis, choice of therapy, consultation, and documentation.The 3-D scanners were successfully validated for their intraoperative application to several patients. With their introduction, an intraoperative, objective measurement of volume to evaluate form and symmetry was possible.In this work, we share our first experience with the intraoperative use of new mobile 3D camera systems, discuss pros and cons, and show selected patient examples.

Recent studies underscored the clinical potential of adipose-derived multipotent stem-/precursor cells (ASPCs). One of the main hurdles en route to clinical application was to isolate cells without having to perform expansion cultures outside the OR. A new generation of clinically approved, commercially available cell separation systems claims to provide ASPCs ready for application without further expansion cultures. However, it is unclear if the new systems yield sufficient cells of adequate quality for the use in autologous murine models. The aim of this study was to isolate and characterize adipose-derived precursor cells taken from the inguinal fat pat of wistar rats using InGeneron's clinically approved ARC™-cell separation system.We isolated cells from the inguinal fat pad of 3 male Wistar rats according to the manufacturer's protocol. In order to reduce the influence of the atmospheric oxygen on the multipotent precursor cells, one half of the cell suspension was cultivated under hypoxia (2% O2) simulating physiological conditions for ASPCs. As a control, the other half of the cells were cultivated under normoxia (21% O2). Cell surface markers CD90, CD29, CD45 and CD11b/c were analyzed by FACS, and osteogenic and adipogenic differentiation of the ASPCs was performed. Finally, cellular growth characteristics were assessed by evaluation of the cumulative population doublings and CFU assay, and metabolic activity was evaluated by WST-1 assay.Processing time was 90 (± 12) min. 1 g of adipose tissue yielded approximately 60 000 plastic adhering cells. Both groups showed a high expression of the mesenchymal stem cell markers CD90 and CD29 while they were negative for the leucocyte markers CD45 and CD11b/c. A strong osteogenic differentiation and a sufficient adipogenic differentiation potential was proven for all ASPCs. Under hypoxia, ASPCs showed increased proliferation characteristics and CFU efficiency as well as a significantly increased metabolic activity.This study showed that sufficient multipotent ASPCs of appropriate quality can be isolated from the inguinal fat pad of Wistar rats using the ARC™-cell separation system. As shown in previous studies, cultivation of cells under hypoxic conditions increased their stemness. Our findings will enable future studies that focus on autologous transplantation of ASPCs in a rat model, which most closely resembles a possible clinical application.

Despite recent medical progress primary and secondary lymphedemas still represent a therapeutic challenge and they often lead to a significant reduction in quality of life. Lymphedemas usually develop in the extremities, the male external genitals as well as the female breast as a consequence to the axial alignment of the lymphatic collectors. Early stages are characterized by an excess of lymph fluid increasing the volume of the affected part of the body whereas later stages represent an increasing amount of solid tissue. Thus therapeutic efforts can focus on the reduction of the surplus of liquid and/or solid components. Generally there are conservative and operative strategies. Conservative measures mainly focus on the improvement of fluid mobilization and drainage and comprise compression garments, manual lymphatic drainage, and apparative intermittent compression. Operative approaches comprise procedures for surgical tissue reduction (symptomatic/ablative approaches) and/or procedures with the intention of enhancing lymphatic transport (causal approaches). Surgical tissue reduction can be performed by open resection and/or liposuction. Traditional surgical causal techniques such as transposition of local flaps aim at leading lymph away from the congested region of the body. Modern microsurgical causal approaches contain methods of reconstruction of interrupted lymphatic pathways as well as techniques for the conduction of lymph into local veins. In this review we depict and discuss the features of the multiform spectrum of the surgical therapy of lymphedemas on the basis of literature as well as our own clinical and experimental experience.

Seit Fruhjahr 2011 steht in Europa mit der Kollagenase (Xiapex ® , Pfizer, Deutschland) ein medikamentoses Verfahren zur enzymatischen Andauung des Dupuytren-Kontrakturstrangs zur Verfugung. Die vorliegende Arbeit fasst die ersten Erfahrungen mit der klinischen Anwendung dieses Praparats zusammen. Im Rahmen der vorliegenden Studie wurden an unserem Zentrum bis dato 16 Injektionen an insgesamt 12 Dupuytren-Kontrakturstrangen an 8 Patienten durchgefuhrt. Das mittlere Alter der Patienten betrug 62,5 (48–74) Jahre. Die Herstellung der Gebrauchslosung und die Injektion erfolgten gemas Empfehlungen des Herstellers. Bei Beteiligung sowohl des Fingergrundgelenkes (MP-Gelenkes) als auch des Mittelgelenkes (PIP-Gelenkes) erfolgten die Injektionen 2-zeitig. 5-mal wurde ausschlieslich uber dem MP-Gelenk injiziert, 4-mal ausschlieslich uber der Grundphalanx des betroffenen Fingers und 3-mal uber beiden. Vor der Behandlung und 14 Tagen nach der manuellen Strangdurchbrechung wurde die Beugekontraktur des behandelnden Gelenkes mittels eines Winkelmessers fur kleine Gelenke gemessen. Nebenwirkungen und Komplikationen wurden unmittelbar bei Auftreten schriftlich erfasst. Des Weiteren wurde erfasst, ob die Patienten nach Behandlung Schmerzmittel einnahmen. Die Gesamtbeugekontraktur aller behandelten Finger konnte durch die Behandlung signifikant von 103°±12° auf 37°±9° reduziert werden. Im MP-Gelenk war die Beugekontraktur von 47°±8° auf 14°±5° und im PIP-Gelenk von 69°±10° auf 37°±11° zuruckgegangen (p Die Kollagenasebehandlung erscheint nach den ersten Erfahrungen eine sichere und effektive Methode ohne Operationstrauma zur Therapie der Dupuytrenschen Kontraktur darzustellen. Pro Injektion kann allerdings immer nur ein Gelenk an einem Finger behandelt werden. Entgegen der prima vista simpel erscheinenden Masnahme ist zur Optimierung des Behandlungsergebnisses und zur Minimierung von Komplikationen besonderes Augenmerk auf die fachgerechte Applikation der Substanz zu richten. Bedingung fur den Einsatz dieser Therapie sind demzufolge prazise anatomische Kenntnisse sowie Bereithaltung handchirurgischer Interventionsmoglichkeiten. Vor allem die Langzeitrezidivraten werden den Stellenwert dieser Behandlungsmethode in Bezug zur perkutanen Nadelfasziotomie und insbesondere zur partiellen Aponeurektomie bestimmen.

Phalloplasty in female-to-male transsexuals is a very demanding procedure concerning preoperative planning and surgical implementation and many operative techniques have been described in the past. Here we illustrate the phalloplasty by means of a pedicled anterolateral-thigh-flap ("ALT-flap") in a patient who underwent unsuccessful groin-flap-phalloplasty alio loco. The sensible innervation was constituted via coaptation to a branch of the pudendal nerve. The technique presented here shows an aesthetically appealing result 6 months postoperatively with a 2-point discrimination of 2.5 cm and ongoing reinnervation. The operative time was reasonable with 360 min. The benefit of a pedicled transposition vs. a free transplantation becomes obvious especially as a salvage procedure in a preoperated situs with altered vascular anatomy. Additionally the shortened operating time and the lack of possible complications of microvascular anastomoses bear advantages. In conclusion we consider this technique for phalloplasty concerning operating time and effort, complications, donor site morbidity and aesthetic result as an appropriate alternative to established methods in selected patients.

Preoperative Doppler ultrasonography for planning free perforator flaps is widely established to identify preoperatively perforators. The method allows one to localise the penetrating point of the perforator through the abdominal fascia. By this means it is not possible to see the intramuscular course or the position of the perforator in relation to the inferior epigastric artery. Lately the technique of computed tomographic angiography provides an opportunity for visualising the course of perforator vessels in these tissues. This paper summarises our experience with the preoperative CT angiography in our breast centre. Since spring 2009 we have reconstructed the breasts of 44 female patients by using free flaps from the lower abdominal wall. 6 of these were bilateral. In a total number of 50 breast reconstructions we used 23 deep inferior epigastric perforator (DIEP) flaps and 27 muscle-sparing transverse rectus abdominis muscle (TRAM) flaps. In addition to the preoperative ultrasonography, a CT angiography of the lower abdomen was conducted in 29 patients. On average they showed at least 2 perforators on the left as well as right abdominal sides, which could be used as flap vessels based on their signal intensity. Based on their estimated microsurgical dissection complexity, the perforator vessels could be classified into 3 groups: 1) direct perforators of category A with short intramuscular course (39%), 2) perforators with long intramuscular course of category B (50%) and 3) "turn around" perforators of category C, which pass medially around the rectus abdominis (11%). The technique of CT angiography permits a reliable preoperative visualisation of perforators in their entire course and facilitates the selection of the supplying perforator as well as the intraoperative procedure for the surgeon. The suggested classification of perforators into 3 groups simplifies the preoperative assessment of the microsurgical dissection effort. Compared to the commonly used Doppler ultrasonography there are disadvantages like the additional cost factor and the radiation exposure. However, in our experience the more detailed planning increases the safety of flap raising and reduces surgery time, so that we consider CT angiography a positive tool to facilitate free perforator flaps.

Most cases of obstetrical brachial plexus palsies are mild traction injuries which resolve under physical therapy within several weeks or months. Severe ruptures or avulsion injuries of the plexus can lead to lifelong impairment of the upper extremities. Hence, in severe brachial plexus injuries the indications for brachial plexus reconstruction should be evaluated, early. At the age of about 3 months, the infant should be presented in a centre specialised in obstetrical brachial plexus palsies. In almost all cases intensive physical therapy is performed. In addition, many patients require splinting in order to gain function as part of the conservative therapy or for postoperative fixation. Depending on the type of splint, different demands are made on design, material and strategy of adjustment. Many different natural and synthetic materials are available for orthopaedic constructions. Because of its good adjustment options, the use of low temperature thermoplastic is steadily increasing. This contribution presents an overview of our currently used splints, new technical developments in our experience with more than 200 patients with obstetrical brachial plexus palsy. We present our experience with the most common splints for the use in fixation after birth-related brachial plexus surgery, subscapularis release, trapezius muscle transfer and functional improvement of hands with a lack of wrist extension.

INTRODUCTION: Injection injuries of the hand are often underestimated because the full extent of the injury often only emerges after a delay. Flap coverage is often needed to avoid amputation. CASE REPORT: In the case presented an epoxy resin injection trauma to the left index finger occurred. A critical blood circulation resulted and after demarcation of the injury a radical debridement was carried out. A heterodigital island flap was used to reconstruct the dorsum of the finger and 3 years after the trauma the patient has no impairments in daily activities. DISCUSSION: The extent of the injury and the carcinogenic properties of the injected material are crucial for adequate treatment of injection injuries. Patients should be referred to specialized hand centers at an early stage. Language: de

In parallel with aging, increasing skin laxity and subcutaneous atrophy occur in many regions of the human body. Apart from the most obvious facial region, where most aesthetic operations for rejuvenation are done, also the dorsum of the hand is continuously visible in daily life. This region exhibits skin laxity, subcutaneous atrophy and age-related pigmentations in a comparable manner to the face. Autologous transplantation of fatty tissue (structural fat grafting, lipofilling) enables subcutaneous regeneration by refilling the subcutaneous space and hence reducing some of the age-related degenerative process. This paper illustrates the special operative technique on the hand in the form of a case report. Furthermore, 3D surface laser scanning permits an objective evaluation of the permanent volume effect over time. In the presented case a volume effect of 69% of the injected volume was measured after 6 months follow-up time. This amount of injected tissue seems to be integrated as a graft and results in a reduction of subcutaneous atrophy in terms of a true regeneration. Structural fat grafting of the dorsum of the hand is thus a method of regenerative medicine. Together with other methods which reduce the age-related pigmentations, it plays a key role in our treatment concept for rejuvenation of the hand.

Plastic surgery has passed through a very positive evolution in the last decades on the solid fundament of constantly developing academic plastic surgery. Aim of this paper is an objective evaluation of the current status of academic plastic surgery regarding research topics, currently available ressources and scientific outcome based on a questionnaire. The return rate of the questionnaire in academic departments was 92%. Main topics in research besides wound healing were topics from regenerative medicine such as tissue engineering, biomaterials, genetherapy and angiogenesis with the main focus on skin and fat tissues. In the past five years a total of 25 million Euros of third party research grants were raised. Research relied mainly on interdisciplinary research facilities. Regarding the scientific outcome more than 200 scientific papers were published in basic science research journals having an impactfactor higher than two. These results clearly demonstrate that plastic surgery is scientifically highly productive in academic surroundings where independent departments are established. Considering that independent units of plastic surgery exist in a relatively small number of all 36 university hospitals in germany, it has to be claimed for further independent departments so to provide adequate research facilities for further evolution of academic plastic surgery.

Despite its recognition as an independent specialty, at German university hospitals the field of plastic surgery is still underrepresented in terms of independent departments with a dedicated research focus. The aim of this study was to analyse the publication performance within the German academic plastic surgery environment and to compare independent departments and dependent, subordinate organisational structures regarding their publication performance.Organisational structures and number of attending doctors in German university hospitals were examined via a website analysis. A pubmed analysis was applied to assess the publication performance (number of publications, cumulative impact factor, impact factor/publication, number of publications/MD, number of publications/unit) between 2009 and 2013. In a journal analysis the distribution of the cumulative impact factor and number of publications in different journals as well as the development of the impact factor in the top journals were analysed.Out of all 35 university hospitals there exist 12 independent departments for plastic surgery and 8 subordinate organisational structures. In 15 university hospitals there were no designated plastic surgery units. The number of attending doctors differed considerably between independent departments (3.6 attending doctors/unit) and subordinate organisational structures (1.1 attending doctors/unit). The majority of publications (89.0%) and of the cumulative impact factor (91.2%) as well as most of the publications/MD (54 publications/year) and publications/unit (61 publications/year) were created within the independent departments. Only in departments top publications with an impact factor 5 were published. In general a negative trend regarding the number of publications (- 13.4%) and cumulative impact factor (- 28.9%) was observed. 58.4% of all publications were distributed over the top 10 journals. Within the latter the majority of articles were published in English journals (60% of publications, 79.9% of the cumulative impact factor). The average impact factor of the top 10 journals increased by 13.5% from 2009 to 2013.In contrast to subordinate and dependent organisational structures, independent departments of plastic surgery are the key performers within German academic plastic surgery which, however, suffers from a general declining publication performance. Hence, the type of organisational structure has a crucial influence on the research performance.

Therapy of scapholunate advanced collapse (SLAC) wrist should be guided by the degree of arthritic changes within the radioscaphoid and midcarpal joints (stage 1-3 after Watson). Diagnostic investigations usually include X-ray imaging and wrist arthoscopy. In the present study, the interrater reliability of SLAC wrist stage classification by means of X-ray image analysis was evaluated between radiologists and hand surgeons. Ultimately, the influence of diagnostic wrist arthroscopy on the final stage classification was determined.Retrospectively, 38 SLAC wrists of 37 patients were included in this study. Conventional X-ray images in a dorso-palmar and lateral view were performed before diagnostic wrist arthroscopy. The degree of carpal collapse on X-rays was determined by 2 radiologists and 2 surgeons (1 board certified hand surgeon, 1 plastic surgeon, both experienced in hand surgery since years). After 14 days the stages were re-evaluated by the surgeons with the digital images from the wrist arthroscopies at hand.While the interrater reliability turned out to be 'weak' amidst the radiologists, it was classified as 'light' among the surgeons. We found a 'weak' and a 'light' interrater reliability between the surgeons and the radiologists. Radiologists tended to assess the degree of severity higher than surgeons. The additional knowledge of the digital arthroscopy images led to a different classification in 55%. When X-rays were assessed in combination with the arthroscopy findings, both stage 1 and stage 3 were diagnosed less frequently.Our study suggests that interpreting X-ray films alone is an unreliable method to assess the stage of SLAC wrist. We believe that additional diagnostic measures such as wrist arthroscopy are needed to accurately diagnose the SLAC wrist stage.

Background/Goal: An arthroscopically assisted management of intra-articular distal radius fractures may improve the quality of reduction. Furthermore, concomitant ligament and triangular fibrocartilage complex injuries can be identified and treated. However, this approach increases the duration of surgery. If severe soft tissue lesions, such as SL-ligament disruptions are treated simultaneously, a longer post-operative immobilisation will be required. The aim of this study was to measure the clinical outcome one year after arthroscopically assisted treatment of intra-articular distal radius fractures.In a retrospective study from 2011 to 2013 we identified 27 patients with intra-articular distal radius fractures who were treated with volar fixed angle plates in an arthroscopically assisted fashion. The amount of associated injuries, the duration of surgery and the time of immobilisation were documented. One year postoperatively we evaluated 23 of these patients using several scores. Patient satisfaction, range of motion, visual analogue scale and grip strength were assessed using a standardised questionnaire.The mean surgery time was 111 min (60-190 min). On average, we found 1.4 (0-3) associated injuries per patient. Seventy percent (19) of all patients had a triangular fibrocartilage complex lesion, 67% (16) had some degree of scapholunate ligament lesion. The mean number of interventions in addition to the plate fixation was 1.1 per patient (0-3). Among these were debridements of the triangular fibrocartilage complex in 11 cases (41%) and scapholunate ligament repairs in 4 cases (15%). The mean immobilisation time was 22 (0-42) days. At one year after surgery, the mean Mayo wrist score was 79 (65-95) and the DASH score was 12 (0-49).The arthroscopically assisted management of intra-articular distal radius fractures helps to identify and treat associated injuries. However, it results in extended surgery and immobilisation time, especially if concomitant intra-articular lesions are treated. In our group of patients, the clinical outcome after one year was nonetheless very good.

Limb-sparing surgery is considered as first choice in most patients with soft tissue sarcomas of the extremities. 5-year survival rates after limb soft tissue sarcoma resection have been promising in many specalised interdisciplinary centres. Quality of life as well as extremity function have thus become an integral aspect of the surgical management of soft tissue sarcomas of the extremities.We herein report on our experience in the anatomic reconstruction of the extremities following limb-sparing soft tissue sarcoma resection using microvascular gracilis muscle flap and skin grafts.Between 2012 and 2014 an anatomic reconstruction of the hand and foot using gracilis muscle flaps following limb-sparing sarcoma resection (leiomyosarcoma N=2, myxofibrosarcoma N=2, clear cell sarcoma N=1, myxoinflammatory fibroblastic sarcoma N=1, granular cell tumour N=1, pleomorphic sarcoma N=1) was performed in N=8 patients (4 females, 4 males), average age: 44 years (23-76 years), average follow-up time 444 days (98-820).In all patients successful defect coverage with unimpaired wound healing was achieved (adjunctive radiotherapy n=4). The tendon of the harvested gracilis muscle was used for anatomic reconstruction of consequently resected essential anatomic structures (extensor retinaculum n=1, flexor/extensor tendons n=4, extensor expansion n=2, tendon reinsertion n=1, proximal interphalangeal joint collateral ligament n=4, dorsal metatarsal ligament n=1). During follow-up neither local recurrence nor metastasis was observed.Reconstruction of multidirectional stability as well as restoring biomechanics and kinetics of the hand and foot should be considered during defect coverage and dead space obliteration management after sarcoma resection of the extremities. For reasons of sound options in anatomic extremity reconstruction with minimal donor site morbidity, the gracilis muscle flap excels in the field of limb-sparing sarcoma resection.

A regular tissue functioning requires the adequate supply of oxygen and nutrient via blood vessels. The sequences of formation and maturation of vessels are initiated and maintained by different growth factors. The VEGF growth factor plays an exceptional role in these mechanisms. The creation of sublethal ischemia as an angiogenic stimulus known as "Delay" is a well established procedure in plastic surgery, although the underlying molecular biological mechanisms still remain unknown. The important role of VEGF and its regulation depending on oxygen pressure suggest a strong connection between this growth factor and the delay phenomenon. The VEGF concentration in skin and underlying muscle was measured in overdimensioned random pattern flaps on 32 male Sprague-Dawley rats after either VEGF gene therapy or circumcision without elevation of the flap and compared to controls. Additional random pattern flaps were raised seven days post gene therapy or delay. The effect on the flap perfusion was measured postoperatively using Indocyanine green Laser Fluoroscopy and the size of the surviving and necrotic areas of the flaps were analysed. The skin of the random pattern flaps showed both in the Delay group and in the VEGF gene therapy group a significantly elevated VEGF concentration compared to the controls. The underlying rectus abdominis muscle showed no significant differences in VEGF concentration between the groups. The flap perfusion postoperatively was significantly increased solely in the VEGF gene therapy group. The analysis of the surviving area of the flaps showed a significant increase over the controls in the gene therapy group. The Delay procedure results in a significantly and locally raised concentration of the VEGF growth factor. The gene therapeutical use of this growth factor allows us to raise flap perfusion and to reduce necrosis. Both VEGF gene therapy and Delay seem to promote similar mechanisms whereas the gene therapy produced superior results in this setting.

Prediction of necrosis in critically perfused skin flaps is difficult and rarely precise. An early detection of insufficiently perfused skin is highly desirable since it may lead to surgical decisions such as operative flap revision or early resection. The application of laser-induced indocyanine green (ICG) fluoroscopy allows an objective quantification of skin perfusion and a high topographical resolution. Aim of the present study is to determine a threshold value for flap perfusion under well-defined experimental conditions and test the validity of the results in the clinical application. Twenty overdimensioned random pattern flaps with a length to width ratio of 4 : 1 (8 x 2 cm) were dissected at the anterior abdominal wall of 20 male Sprague-Dawley rats weighing 365 g on average. ICG fluorescence was performed at the end of the operation by intravenous injection of 1 g ICG/kg bodyweight into a tail vein and digital recording. On the seventh postoperative day, both the necrotic and surviving areas of the flaps were measured and the ICG-fluorescence was analysed in the areas that had undergone necrosis. 41 flaps with areas of critical perfusion (18 skin flaps, 13 muscle flaps, 8 replantations) were analysed in 39 patients. The surviving part of the flap had a mean perfusion index of 62 % compared to reference skin. The distal parts of the flap that necrotized during the experiment showed an average perfusion index of 19 % postoperatively. Differences were statistically significant (p < 0.001). In clinical application, a number of 13 flaps were found to have a perfusion index less than 25 % in a region of critical perfusion. Eleven of these developed a partial necrosis in that region, one flap underwent total necrosis. Indocyanine green fluoroscopy allows a detailed topographical analysis of flap perfusion and the prediction of necrosis. Experimental findings presented a threshold value for the perfusion index of 25 % which could be confirmed in clinical application.

PURPOSE: Medical profession lost continuously attractiveness due to various reasons (insufficient training, irregular working time, decreasing income) in the last years. This does notably apply to surgical disciplines. In a survey should be clarified to what extent this dissatisfaction may be the case for residents and young specialists in plastic surgery. MATERIAL AND METHODS: A questionnaire was sent to all associated members of the "Vereinigung der Deutschen Plastischen Chirurgen (VDPC)" and was published in the communication journal of the VDPC. The questionnaire was sent back by 91 surgical residents or newly specialists (about 19 % of all). RESULTS: A well structured residency program existed for 47 %. 40 % of the residents were satisfied with the teaching assistance by their clinical teachers in the OR, whereas the fewest surgical procedures were done in the field of aesthetic surgery (n = 7). At least once per year it was possible for 80 % to take part in seminars or congresses. Therefore 45 % had to take holyday. For 44 % no financial support was paid. As perspective 30 % aim a career advancement in their hospitals and 18 % aim a private practice as plastic surgeon. CONCLUSION: To some extent training structures in plastic surgery are not well established. An urgent challenge should be to develop improvements in the continuing education in plastic surgery. This includes an increase in internal training, an organised rotation of residents between different hospitals, and structured mentoring of the residents.

Prediction of necrosis has a clinical relevance in all fields of plastic surgery. The new application of indocyanine green (ICG) fluoroscopy in plastic surgery allows an objective quantification of skin perfusion and a high topographical resolution. The aim of the present study is to determine threshold values for flap perfusion under well-defined experimental conditions. Twenty random pattern flaps with a length to width ratio of 4:1 (8 x 2 cm(2)) were dissected on the anterior abdominal wall of 20 male Sprague-Dawley rats. ICG fluoroscopy was performed at the end of the operation. The animals were sacrificed at the seventh postoperative day with a reliable necrosis of the distal part of the flaps. Postoperative ICG fluoroscopy then was analysed both in regions that will survive and undergo necrosis. At day 7 a mean area of 5.5 cm(2) (57% of the total flap area) survived and a mean of 3.8 cm(2) (43%) became necrotic. The surviving part of the flap had a mean perfusion index of 62% compared to reference skin. The distal parts of the flap that necrotised showed an average perfusion index of only 19% postoperatively. Differences were statistically highly significant (p

Background Vascular endothelial growth factor (VEGF) is a key regulator of angiogenesis. VEGF A also plays an important role in wound healing of the skin by promoting angiogenesis and by stimulating blood vessel growth. Therefore we tested the hypothesis that flap survival could be increased by the preoperative injection of AdVEGF165. Methods We studied the effect of AdVEGF165 in an overdimensioned ischemic random-pattern-flap model in the rat (n = 50) with a length-to-width ratio of 4 : 1. VEGF cDNA was administered in two concentrations of 5 × 108 plaque-forming units (pfU) and 1 × 109 pfU using a recombinant adenoviral vector. Recombinant virus was injected subdermally 7, 3 or 0 days prior to flap harvest for the lower concentration and 7 days prior for the higher concentration. Flap survival and necrosis were observed at day 7, the day the animals were sacrificed. Results Adenoviral gene transfer with VEGF165 3 and 7 days before flap harvest showed a significantly increased flap survival of 50% together with a significantly reduced necrosis (p < 0.01). Injection using a titer of 1 × 109 pfU 7 days prior to surgery increased flap survival even more, though failing to reach statistical significance compared to the lower concentration. VEGF protein concentration in the injected skin was significantly higher than in controls (p < 0.01). Flap perfusion was increased as well, demonstrated by indocyanine green (ICG) fluoroscopy (p < 0.001). Conclusions Our results confirm the important role of VEGF165 on angiogenesis in ischemic flaps. Indeed by injecting VEGF165 at 3 to 7 days preoperatively in a concentration of 1 × 109 pfU our data show that length-to-width ratio for random-pattern-flaps could be increased from 2 : 1 to 3 : 1 and therefore may allow a wider range of applications of this simple flap technique. Copyright © 2004 John Wiley & Sons, Ltd.

Background: Management of soft tissue defects of the hand is one of the most challenging issues in hand surgery.

Extravasations of chemotherapeutic drugs may lead to large soft-tissue losses in the hand and forearm and necessitating surgical excision with secondary flap coverage. Unfortunately, a delayed referral to a hand and plastic surgical unit with an already established soft-tissue defect is most common. Nevertheless, in our unit the method of choice is early emergency subcutaneous "wash-out", which facilitates dilution and reduction of concentration of the extravasation and therefore reliably avoids the development of soft-tissue defects. The aim of this paper is to present the surgical technique.

Perforator flaps allow an individual flap design on the basis of a preoperative ultrasound examination. Aim of the present study is a preliminary evaluation of results and technical pitfalls of this new technique in the use for flap coverage on the dorsum of the hand and the elbow region. Since 1999, seven individually designed pedicled perforator flaps were prepared on the upper extremity. In four cases, defects on the dorsum of the hand and in a further three defects in the elbow region were treated. In the latter cases the flaps were harvested in a mainly epifascial plane, without dissecting the perforating vessels down to their origin. Five flaps were based on perforating vessels of the interosseous arteries, a further two from the lateral collateral humeral artery. Three out of four pedicled perforator flaps used on the dorsum of the hand healed completely. One flap was lost because of venous insufficiency due to the lack of wrist immobilisation. In the elbow region, two out of three defects were successfully covered with an individual perforator flap. One flap was lost due to venous insufficiency, a further needed an additional split-skin graft with a partial flap loss. The main advantage of the presented technique remains the possibility of individual flap design. However, the donor-site defect is almost negligible since in most cases a primary closure of the donor site was possible. The main arteries remained untouched leaving the blood supply to the hand unchanged. Nevertheless, the mainly epifascial harvest of the perforating vessels in the elbow region has the disadvantage of a short pedicle together with a high degree of torsion which leads to an increased risk of flap loss due to venous insufficiency.

A new approach of using photographs from smartphones for three-dimensional (3D) imaging was introduced besides the standard high quality 3D camera systems. In this work, we investigated different capture preferences and compared the accuracy of this 3D reconstruction method with manual tape measurement and an established commercial 3D camera system.The facial region of one plastic mannequin head was labelled with 21 landmarks. A 3D reference model was captured with the Vectra 3D Imaging System®. In addition, 3D imaging was executed with the Autodesk 123d Catch® application using 16, 12, 9, 6 and 3 pictures from Apple® iPhone 4 s® and iPad® 3rd generation. The accuracy of 3D reconstruction was measured in 2 steps. First, 42 distance measurements from manual tape measurement and the 2 digital systems were compared. Second, the surface-to-surface deviation of different aesthetic units from the Vectra® reference model to Catch® generated models was analysed. For each 3D system the capturing and processing time was measured.The measurement showed no significant (p0.05) difference between manual tape measurement and both digital distances from the Catch® application and Vectra®. Surface-to-surface deviation to the Vectra® reference model showed sufficient results for the 3D reconstruction of Catch® with 16, 12 and 9 picture sets. Use of 6 and 3 pictures resulted in large deviations. Lateral aesthetic units showed higher deviations than central units. Catch® needed 5 times longer to capture and compute 3D models (average 10 min vs. 2 min).The Autodesk 123d Catch® computed models suggests good accuracy of the 3D reconstruction for a standard mannequin model, in comparison to manual tape measurement and the surface-to-surface analysis with a 3D reference model. However, the prolonged capture time with multiple pictures is prone to errors. Further studies are needed to investigate its application and quality in capturing volunteer models. Soon mobile applications may offer an alternative for plastic surgeons to today's cost intensive, stationary 3D camera systems.

In contrast to the classical fasciocutaneous and musculocutaneous flaps, perforator flaps are supplied only by a single perforating branch. The aim of this paper is to present the surgical technique and to discuss the use of perforator flaps in hand surgery. Our previous studies have demonstrated the reliability of a preoperative Doppler for planning perforator flaps in reconstructive surgery of the breast: With 286 preoperatively localized perforating branches, a total of 162 were confirmed in intraoperative dissection. In 37 out of these 46 perforator flaps (80%), a preoperatively localized perforating branch could be used. Based on these results, the individual design of perforator flaps harvested on the forearm for defects on the dorsum of the hand is possible. In a preoperative Doppler exam, a perforating branch, i.e. of the posterior interosseous artery, can be localized. The intraoperative confirmation of the perforating branch allows the successful defect coverage with a distally pedicled flap without taking fascia or septum. In our experience, this possibility of planning an individually designed perforator flap is the major advantage for applications of the perforator flap technique in hand surgery. This is especially true in cases where the harvest of a fasciocutaneous flap is unreliable or impossible due to anatomic variations. On the other hand, the dissection of the pedicle is technically demanding and the individual distribution of the perforating branches requires a high degree of flexibility. However, we do consider this new technique to be a further extension in the armamentarium for soft-tissue coverage of the hand.

Free tissue transplantation is a routine procedure in reconstructive surgery. Although a lot of free flap techniques have been described, the postoperative management of complications has gained only little interest. Nevertheless, complications of perfusion after free tissue transplantation are not rare and require a systematic approach. The aim of this study is to classify perfusion failures with a simple grading system prospectively on a large clinical series and to evaluate the results of treatment to improve management. In the past ten months, 70 consecutive free flaps have been performed. By the end of the operation, the operating surgeon gave a prognosis concerning the probability of a possible perfusion complication. Postoperative monitoring was done exclusively by clinical examination (colour, time for recapillarisation and bleeding after puncture). According to these parameters, arterial and venous insufficiencies have been classified into four grades. After recording type, time and treatment of a postoperative complication, the result of treatment was rated subjectively and a cause was noted when possible. The final result was classified either as total flap loss, partial flap loss or successful tissue transplantation. A total of 28 (40%) complications, which were treated with an average of 2.1 options, were recorded. The ratio between arterial and venous failure was 15:13. In 21 cases surgical intervention became necessary (intraoperative n = 12, postoperative n = 9). The arising complication was diagnosed correctly in nine cases by the operating surgeon. In ten cases, the cause of the complication remained unclear. In 18 cases, the complication was treated successfully without any flap loss. In six cases partial flap loss was observed and in four cases a total flap loss had to be accepted. Our results confirm that only few objective criteria for treatment options with perfusion failures after free tissue transplantation exist. Nevertheless, the presented classification is a useful tool for standardized evaluation of the results. The various salvage techniques result in positive outcomes for most of the patients.

On occasion of the 50th anniversary of the department of plastic and reconstructive surgery at the Klinikum rechts der Isar of the Technische Universitat in 2008 Ursula Schmidt-Tintemann is honoured by this historical article. As one of the first departments of plastic surgery in Germany the department became under her guidance a role model for other departments. Furthermore, Ursula Schmidt-Tintemann contributed to the characterization and establishment of the surgical specialty plastic surgery in Germany by numerous activities. Her special interest were ethical aspects of plastic surgery and aesthetic surgery. As the founder of the department Ursula Schmidt-Tintemann is to be regarded as one of the giants in plastic surgery of post war Germany.