142 results on '"Rückle, Thomas"'
Search Results
2. Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study
3. The p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitors
4. The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors.
5. DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection
6. Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study
7. Critical role for phosphoinositide 3-kinase gamma in parasite invasion and disease progression of cutaneous leishmaniasis
8. Efficacy and safety of temelimab in multiple sclerosis: Results of a randomized phase 2b and extension study
9. sj-pdf-1-msj-10.1177_13524585211024997 – Supplemental material for Efficacy and safety of temelimab in multiple sclerosis: Results of a randomized phase 2b and extension study
10. sj-pdf-2-msj-10.1177_13524585211024997 – Supplemental material for Efficacy and safety of temelimab in multiple sclerosis: Results of a randomized phase 2b and extension study
11. Regulation of the severity of neuroinflammation and demyelination by TLR‐ASK1‐p38 pathway
12. Inactivation of PI3Kγ and PI3Kδ distorts T-cell development and causes multiple organ inflammation
13. Efficacy and safety of temelimab in multiple sclerosis: Results of a randomized phase 2b and extension study.
14. A Single-Dose Combination Study with the Experimental Antimalarials Artefenomel and DSM265 To Determine Safety and Antimalarial Activity against Blood-Stage Plasmodium falciparum in Healthy Volunteers
15. Isoform-selective phosphoinositide 3-kinase inhibitors induce apoptosis in chronic lymphocytic leukaemia cells
16. Insulin Granule Recruitment and Exocytosis Is Dependent on p110γ in Insulinoma and Human β-Cells
17. DSM265 at 400 Milligrams Clears Asexual Stage Parasites but Not Mature Gametocytes from the Blood of Healthy Subjects Experimentally Infected with Plasmodium falciparum
18. Importance of Phosphoinositide 3-Kinase γ in the Host Defense against Pneumococcal Infection
19. Synthesis and characterization of constrained cyclosporin A derivatives containing a pseudo-proline group
20. Pseudo-prolines in cyclic peptides: Conformational stabilisation of cyclo[Pro-Thr(ψ Me,Mepro)-Pro]
21. Improved safety margin for embryotoxicity in rats for the new endoperoxide artefenomel (OZ439) as compared to artesunate
22. A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study
23. Improved safety margin for embryotoxicity in rats for the new endoperoxide artefenomel (OZ439) as compared to artesunate.
24. Phosphoinositide-3 kinase γ required for LPS-induced transepithelial neutrophil trafficking in the lung
25. PI3Kgamma (PI3Kγ) is essential for efficient induction of CXCR3 on activated T cells
26. Erratum: Corrigendum: The p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitors
27. PI3Kγ regulates cartilage damage in chronic inflammatory arthritis
28. BMP2 induction of actin cytoskeleton reorganization and cell migration requires PI3-kinase and Cdc42 activity
29. Phosphoinositide 3-Kinase p110β Activity: Key Role in Metabolism and Mammary Gland Cancer but Not Development
30. Genetic and Pharmacological Targeting of Phosphoinositide 3-Kinase-γ Reduces Atherosclerosis and Favors Plaque Stability by Modulating Inflammatory Processes
31. Isoform-Specific Functions of Phosphoinositide 3-Kinases: p110δ but Not p110γ Promotes Optimal Allergic Responses In Vivo
32. Phosphoinositide 3-Kinase γ Inhibition Plays a Crucial Role in Early Steps of Inflammation by Blocking Neutrophil Recruitment
33. PI3Kγ inhibition: towards an 'aspirin of the 21st century'?
34. Furan-2-ylmethylene Thiazolidinediones as Novel, Potent, and Selective Inhibitors of Phosphoinositide 3-Kinase γ
35. PI3Kγ inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus
36. Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis
37. Design, Synthesis, and Biological Activity of Novel, Potent, and Selective (Benzoylaminomethyl)thiophene Sulfonamide Inhibitors of c-Jun-N-Terminal Kinase
38. Mapping of Synergistic Components of Weakly Interacting Protein-Protein Motifs Using Arrays of Paired Peptides
39. Crystal Structure of a Synthetic Cyclodecapeptide for Template-Assembled Synthetic Protein Design
40. Cover Picture
41. Synthetic routes to NEtXaa4-cyclosporin A derivatives as potential anti-HIV I drugs
42. Pseudo-prolines in cyclic peptides: Conformational stabilisation of cyclo[Pro-Thr(ψMe,Mepro)-Pro]
43. Efficient one-pot synthesis of N-ethyl amino acids
44. 2nd Lausanne Conference on Bioorganic Chemistry, March 6/7, 1997
45. Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells.
46. Genetic and pharmacological targeting of phosphoinositide 3-kinase-gamma reduces atherosclerosis and favors plaque stability by modulating inflammatory processes.
47. Importance of Phosphoinositide 3-Kinase in γ the Host Defense against Pneumococcal Infection.
48. Phosphoinositide 3-Kinase {gamma} Inhibition Plays a Crucial Role in Early Steps of Inflammation by Blocking Neutrophil Recruitment.
49. Synthetic routes to NEtXaa 4-cyclosporin A derivatives as potential anti-HIV I drugs
50. MOESM1 of A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.