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Your search keyword '"Quirk, Avery V."' showing total 6 results
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6 results on '"Quirk, Avery V."'

1. Formaldehyde and Glutaraldehyde Inactivation of Bacterial Tier 1 Select Agents in Tissues

Author

Chua, Jennifer, Bozue, Joel A., Klimko, Christopher P., Shoe, Jennifer L., Ruiz, Sara I., Jensen, Christopher L., Tobery, Steven A., Crumpler, Jared M., Chabot, Donald J., Quirk, Avery V., Hunter, Melissa, Harbourt, David E., Friedlander, Arthur M., and Cote, Christopher K.

Subjects
United States. Centers for Disease Control and Prevention, Formaldehyde, Polymer crosslinking, Health
Abstract

Despite being a disease of antiquity, anthrax remains a public health concern and is considered a reemerging threat in developed countries, in part because of bioterrorism (1). Threats of bioterrorism [...]

Published
2019
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2. Disease progression in mice exposed to low-doses of aerosolized clinical isolates of Burkholderia pseudomallei

Author

Trevino, Sylvia R., primary, Klimko, Christopher P., additional, Reed, Matthew C., additional, Aponte-Cuadrado, Michael J., additional, Hunter, Melissa, additional, Shoe, Jennifer L., additional, Meyer, Joshua R., additional, Dankmeyer, Jennifer L., additional, Biryukov, Sergei S., additional, Quirk, Avery V., additional, Fritts, Kristen A., additional, Kern, Steven J., additional, Fetterer, David P., additional, Kohler, Lara J., additional, Toothman, Ronald G., additional, Bozue, Joel A., additional, Schellhase, Christopher W., additional, Kreiselmeier, Norman, additional, Daye, Sharon P., additional, Welkos, Susan L., additional, Soffler, Carl, additional, Worsham, Patricia L., additional, Waag, David M., additional, Amemiya, Kei, additional, and Cote, Christopher K., additional

Published
2018
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3. A Standard Method To Inactivate Bacillus anthracis Spores to Sterility via Gamma Irradiation

Author

Cote, Christopher K., primary, Buhr, Tony, additional, Bernhards, Casey B., additional, Bohmke, Matthew D., additional, Calm, Alena M., additional, Esteban-Trexler, Josephine S., additional, Hunter, Melissa, additional, Katoski, Sarah E., additional, Kennihan, Neil, additional, Klimko, Christopher P., additional, Miller, Jeremy A., additional, Minter, Zachary A., additional, Pfarr, Jerry W., additional, Prugh, Amber M., additional, Quirk, Avery V., additional, Rivers, Bryan A., additional, Shea, April A., additional, Shoe, Jennifer L., additional, Sickler, Todd M., additional, Young, Alice A., additional, Fetterer, David P., additional, Welkos, Susan L., additional, Bozue, Joel A., additional, McPherson, Derrell, additional, Fountain, Augustus W., additional, and Gibbons, Henry S., additional

Published
2018
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4. AvirulentBacillus anthracisStrain with Molecular Assay Targets as Surrogate for Irradiation-Inactivated Virulent Spores

Author

Plaut, Roger D., primary, Staab, Andrea B., additional, Munson, Mark A., additional, Gebhardt, Joan S., additional, Klimko, Christopher P., additional, Quirk, Avery V., additional, Cote, Christopher K., additional, Buhr, Tony L., additional, Rossmaier, Rebecca D., additional, Bernhards, Robert C., additional, Love, Courtney E., additional, Berk, Kimberly L., additional, Abshire, Teresa G., additional, Rozak, David A., additional, Beck, Linda C., additional, Stibitz, Scott, additional, Goodwin, Bruce G., additional, Smith, Michael A., additional, and Sozhamannan, Shanmuga, additional

Published
2018
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5. Characterization of pathogenesis of and immune response to Burkholderia pseudomallei K96243 using both inhalational and intraperitoneal infection models in BALB/c and C57BL/6 mice

Author

Bearss, Jeremy J., primary, Hunter, Melissa, additional, Dankmeyer, Jennifer L., additional, Fritts, Kristen A., additional, Klimko, Christopher P., additional, Weaver, Chris H., additional, Shoe, Jennifer L., additional, Quirk, Avery V., additional, Toothman, Ronald G., additional, Webster, Wendy M., additional, Fetterer, David P., additional, Bozue, Joel A., additional, Worsham, Patricia L., additional, Welkos, Susan L., additional, Amemiya, Kei, additional, and Cote, Christopher K., additional

Published
2017
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6. Avirulent Bacillus anthracis Strain with Molecular Assay Targets as Surrogate for Irradiation-Inactivated Virulent Spores.

Author

Plaut, Roger D., Staab, Andrea B., Munson, Mark A., Gebhardt, Joan S., Klimko, Christopher P., Quirk, Avery V., Cote, Christopher K., Buhr, Tony L., Rossmaier, Rebecca D., Bernhards, Robert C., Love, Courtney E., Berk, Kimberly L., Abshire, Teresa G., Rozak, David A., Beck, Linda C., Stibitz, Scott, Goodwin, Bruce G., Smith, Michael A., and Sozhamannan, Shanmuga

Subjects
BACILLUS anthracis, IRRADIATION, MICROBIAL virulence, SPORES, MICROBIOLOGICAL assay, ANIMAL experimentation, ANTHRAX, BACILLUS (Bacteria), BACTERIAL toxins, COMPARATIVE studies, GENES, GENETICS, GENETIC techniques, RESEARCH methodology, MEDICAL cooperation, MICE, GENETIC mutation, RADIATION, RESEARCH, RESEARCH evaluation, EVALUATION research
Abstract

The revelation in May 2015 of the shipment of γ irradiation-inactivated wild-type Bacillus anthracis spore preparations containing a small number of live spores raised concern about the safety and security of these materials. The finding also raised doubts about the validity of the protocols and procedures used to prepare them. Such inactivated reference materials were used as positive controls in assays to detect suspected B. anthracis in samples because live agent cannot be shipped for use in field settings, in improvement of currently deployed detection methods or development of new methods, or for quality assurance and training activities. Hence, risk-mitigated B. anthracis strains are needed to fulfill these requirements. We constructed a genetically inactivated or attenuated strain containing relevant molecular assay targets and tested to compare assay performance using this strain to the historical data obtained using irradiation-inactivated virulent spores. [ABSTRACT FROM AUTHOR]

Published
2018
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