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29 results on '"Querbach, Christiane"'

4. Factors Determining Quality of Drug Information by Hospital Pharmacies—Results from Five-Year Annual Quality Assessment.

Author

Strobach, Dorothea, Chiriac, Ute, Klausner, Sigrun, Krebs, Sabine, Langebrake, Claudia, Querbach, Christiane, Schuhmacher, Carolin, Schulte, Rickmer, Wiegrebe, Simon, and Amann, Ute

Subjects
HOSPITAL pharmacies, MEDICAL personnel, DRUG therapy, DATABASES, MULTIVARIATE analysis
Abstract

Drug information (DI) provided by hospital pharmacies aims to promote rational and safe drug therapy. While quality assessment for this task is recommended, more knowledge on the factors determining the quality is needed. We aimed to evaluate the impacts of different factors on the quality of DI provided by hospital pharmacies to healthcare professionals. Retrospectively, answers on fictitious enquiries about annual DI tests for German hospital pharmacies over five years were evaluated for content-related and structural requirements. Multivariate analysis was performed for the impact of the enquiry complexity, DI organization (specialized DI center; pharmacist responsible per day; DI on top of other routine tasks), and quality measures (second look; experience of answering pharmacist in DI/on ward; use of documentation database). In 2017–2021, 45, 71, 79, 118, and 122 hospital pharmacies participated. The enquiry complexity had a statistically significant impact on the content-related quality, with poor results for a higher complexity (years 2018/2021, OR 0.25/0.04, p < 0.01). The DI centers achieved better results regarding content-related quality than for a pharmacist responsible per day (OR 0.76/p = 0.65) or DI on top of routine tasks (OR 0.35/p = 0.02). The DI centers scored better in structural quality. The second look showed an overall trend of a better content-related and structural quality. In conclusion, specialized DI centers and second looks are recommended as quality-improving measures. Training for answering complex enquiries should be intensified. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Rates of bacterial co-infections and antimicrobial use in COVID-19 patients: a retrospective cohort study in light of antibiotic stewardship

Author

Rothe, Kathrin, Feihl, Susanne, Schneider, Jochen, Wallnöfer, Fabian, Wurst, Milena, Lukas, Marina, Treiber, Matthias, Lahmer, Tobias, Heim, Markus, Dommasch, Michael, Waschulzik, Birgit, Zink, Alexander, Querbach, Christiane, Busch, Dirk H., Schmid, Roland M., Schneider, Gerhard, and Spinner, Christoph D.

Published
2021
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11. Incidence of infections due to third generation cephalosporin-resistant Enterobacteriaceae - a prospective multicentre cohort study in six German university hospitals

Author

Rohde, Anna M., Zweigner, Janine, Wiese-Posselt, Miriam, Schwab, Frank, Behnke, Michael, Kola, Axel, Obermann, Birgit, Knobloch, Johannes K.-M., Feihl, Susanne, Querbach, Christiane, Gebhardt, Friedemann, Mischnik, Alexander, Ihle, Vera, Schröder, Wiebke, Armean, Sabina, Peter, Silke, Tacconelli, Evelina, Hamprecht, Axel, Seifert, Harald, Vehreschild, Maria J. G. T., Kern, Winfried V., and Gastmeier, Petra

Published
2018
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13. Validation of adapted daily dose definitions for hospital antibacterial drug use evaluation: a multicentre study

Author

Först, Gesche, de With, Katja, Weber, Nadine, Borde, Johannes, Querbach, Christiane, Kleideiter, Johannes, Seifert, Claudia, Hagel, Stefan, Ambrosch, Andreas, Löbermann, Micha, Schröder, Philipp, Steib-Bauert, Michaela, Kern, Winfried V., Beier, Stephanie, Binesch, Faranak, Burzynski, Beate, Devide, Anette, Donat, Martina, Endler, Katja, Feihl, Susanne, Freidank, Annette, Früchtel-Unterholzner, Edeltraud, Gödde, Norbert, Gründel, Ralf, Grzibiela, Wolfgang, Kaiser, Réné, Kawecki, Piotr, Knoth, Holger, Kohlbrenner, Stefan, Lerner, Johanna, Loers, Edeltraud, Müller, Matthias, Papathanasiou, Nikolas, Probst, Wiltrud, Putzbach, Jens, Reimer, Marion, Reinwald, Ann-Christin, Rusche, Ruth, Scheerer, Martin, and Zessin, Enrico

Published
2017
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16. Prevalence of third-generation cephalosporin-resistant Enterobacterales colonization on hospital admission and ESBL genotype-specific risk factors: a cross-sectional study in six German university hospitals

Author

Rohde, Anna M., Zweigner, Janine, Wiese-Posselt, Miriam, Schwab, Frank, Behnke, Michael, Kola, Axel, Schroeder, Wiebke, Peter, Silke, Tacconelli, Evelina, Wille, Thorsten, Feihl, Susanne, Querbach, Christiane, Gebhardt, Friedemann, Goelz, Hannah, Schneider, Christian, Mischnik, Alexander, Vehreschild, Maria J. G. T., Seifert, Harald, Kern, Winfried, V, Gastmeier, Petra, Hamprecht, Axel, Rohde, Anna M., Zweigner, Janine, Wiese-Posselt, Miriam, Schwab, Frank, Behnke, Michael, Kola, Axel, Schroeder, Wiebke, Peter, Silke, Tacconelli, Evelina, Wille, Thorsten, Feihl, Susanne, Querbach, Christiane, Gebhardt, Friedemann, Goelz, Hannah, Schneider, Christian, Mischnik, Alexander, Vehreschild, Maria J. G. T., Seifert, Harald, Kern, Winfried, V, Gastmeier, Petra, and Hamprecht, Axel

Abstract

Objectives: To assess the admission prevalence of third-generation cephalosporin-resistant Enterobacterales (3GCREB) and to assess whether risk factors vary by beta-lactamase genotype. Methods:Adult patients were recruited within 72h of admission to general wards of six unversity hospitals in 2014 and 2015. Rectal swabs were screened for 3GCREB and isolates were analysed phenotypically and genotypically. Patients were questioned on potential risk factors. Multivariable analyses were performed to identify risk factors for 3GCREB colonization and for specific beta-lactamases. Results: Of 8753 patients screened, 828 were 3GCREB positive (9.5%). Eight hundred and thirteen isolates were available for genotyping. CTX-M-15 was the most common ESBL (38.0%), followed by CTX-M-1 (22.5%), CTX-M-14 (8.7%), CTX-M-27 (7.5%) and SHV-ESBL (4.4%). AmpC was found in 11.9%. Interestingly, 18 Escherichia coli isolates were AmpC positive, 12 of which (67%) contained AmpC on a gene of plasmid origin [CMY (n=10), DHA (n=2)]. Risk factors for 3GCREB colonization varied by genotype. Recent antibiotic exposure and prior colonization by antibiotic-resistant bacteria were risk factors for all beta-lactamases except CTX-M-14 and CTX-M-27. Travel outside Europe was a risk factor for CTX-M-15 and CTX-M-27 [adjusted OR (aOR) 3.49, 95% CI 2.88-4.24 and aOR 2.73, 95% CI 1.68-4.43]. A previous stay in a long-term care facility was associated with CTX-M-14 (aOR 3.01, 95% CI 1.98-4.59). A preceding hospital stay in Germany increased the risk of CTX-M-15 (aOR 1.27, 95% CI 1.14-1.41), while a prior hospital stay in other European countries increased the risk of SHV-ESBL colonization (aOR 3.85, 95% CI 1.67-8.92). Conclusions: The detection of different ESBL types is associated with specific risk factor sets that might represent distinct sources of colonization and ESBL-specific dissemination routes.

Published
2020

17. Rates of bacterial co-infections and antimicrobial use in COVID-19 patients: a retrospective cohort study in light of antibiotic stewardship

Author

Rothe, Kathrin, primary, Feihl, Susanne, additional, Schneider, Jochen, additional, Wallnöfer, Fabian, additional, Wurst, Milena, additional, Lukas, Marina, additional, Treiber, Matthias, additional, Lahmer, Tobias, additional, Heim, Markus, additional, Dommasch, Michael, additional, Waschulzik, Birgit, additional, Zink, Alexander, additional, Querbach, Christiane, additional, Busch, Dirk H., additional, Schmid, Roland M., additional, Schneider, Gerhard, additional, and Spinner, Christoph D., additional

Published
2020
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19. Verdacht auf Penicillinallergie: Risikoabschätzung mit einem Algorithmus als Antibiotic-Stewardship-Projekt

Author

Querbach, Christiane, primary, Biedermann, Tilo, additional, Busch, Dirk H., additional, Eisenhart-Rothe, Rüdiger, additional, Feihl, Susanne, additional, Gebhardt, Friedemann, additional, Heim, Markus, additional, Renz, Helmut, additional, Rothe, Kathrin, additional, Spinner, Christoph D., additional, Starzner, Melanie, additional, Suren, Christian, additional, Trojan, Monika, additional, and Brockow, Knut, additional

Published
2020
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20. Prevalence of third-generation cephalosporin-resistant Enterobacterales colonization on hospital admission and ESBL genotype-specific risk factors: a cross-sectional study in six German university hospitals

Author

Rohde, Anna M, primary, Zweigner, Janine, primary, Wiese-Posselt, Miriam, primary, Schwab, Frank, primary, Behnke, Michael, primary, Kola, Axel, primary, Schröder, Wiebke, primary, Peter, Silke, primary, Tacconelli, Evelina, primary, Wille, Thorsten, primary, Feihl, Susanne, primary, Querbach, Christiane, primary, Gebhardt, Friedemann, primary, Gölz, Hannah, primary, Schneider, Christian, primary, Mischnik, Alexander, primary, Vehreschild, Maria J G T, primary, Seifert, Harald, primary, Kern, Winfried V, primary, Gastmeier, Petra, primary, and Hamprecht, Axel, primary

Published
2020
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23. Strategies for increasing diagnostic yield of community-onset bacteraemia within the emergency department: A retrospective study

Author

Rothe, Kathrin, primary, Spinner, Christoph D., additional, Ott, Armin, additional, Querbach, Christiane, additional, Dommasch, Michael, additional, Aldrich, Cassandra, additional, Gebhardt, Friedemann, additional, Schneider, Jochen, additional, Schmid, Roland M., additional, Busch, Dirk H., additional, and Katchanov, Juri, additional

Published
2019
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25. Entwicklung einer prospektiven Datenbank zur Erfassung periprothetischer Infektionen zur integrierten Therapieplanung und -kontrolle

Author

Suren, Christian, Querbach, Christiane, Rämer, Patrick, Thurner, Jakob, Feihl, Susanne, Schauwecker, Johannes, von Eisenhart-Rothe, Rüdiger, and Mühlhofer, Heinrich

Subjects
periimplantär, Implantatinfekt, ddc: 610, Infektion, Datenbank, interdisziplinär, Erfassung, data mining, 610 Medical sciences, Medicine, periprothetisch, antiinfektiv, Antibiotika, prospektiv
Abstract

Fragestellung: Periprothetische Infektionen (PPI) stellen nicht nur in operativer Hinsicht eine Herausforderung dar. Resistenzen auf antimikrobielle Wirkstoffe, Interaktionen mit der bestehenden Medikation und die Komorbiditäten des Patienten gefährden den Therapieerfolg. Ein interdisziplinäres[zum vollständigen Text gelangen Sie über die oben angegebene URL], Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2017)

Published
2017

26. Susceptibility to cephalosporin combinations and aztreonam/avibactam among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission

Author

Mischnik, Alexander, Baumert, Philipp, Hamprecht, Axel, Rohde, Anna, Peter, Silke, Feihl, Susanne, Knobloch, Johannes, Gölz, Hanna, Kola, Axel, Obermann, Birgit, Querbach, Christiane, Willmann, Matthias, Gebhardt, Friedemann, Tacconelli, Evelina, Gastmeier, Petra, Seifert, Harald, and Kern, Winfried V.

Published
2017
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27. Clinimetric properties and suitability of selected quality indicators for assessing antibiotic use in hospitalized adults: a multicentre point prevalence study in 24 hospitals in Germany.

Author

Först, Gesche, Kern, Winfried V, Weber, Nadine, Querbach, Christiane, Kleideiter, Johannes, Knoth, Holger, Hagel, Stefan, Ambrosch, Andreas, Löbermann, Micha, Schröder, Philipp, Borde, Johannes, Steib-Bauert, Michaela, With, Katja de, Group, ABS-QI Study, de With, Katja, and ABS-QI Study Group

Subjects
ANTIBIOTIC residues, URINARY tract infections, MILITARY hospitals, QUALITY control, ANTIBIOTICS, ADULTS, HOSPITALS
Abstract

Objectives: The capability to measure and monitor the quality of antibiotic prescribing is an important component of antibiotic stewardship (ABS) programmes. Several catalogues of consensus-based structure and process-of-care quality indicators (QIs) have been proposed, but only a few studies have tested and validated ABS QIs in practice tests. This multicentre study determined the clinimetric properties and suitability of a set of 33 process QIs for ABS that had earlier been developed and in part recommended in a German-Austrian hospital ABS practice guideline.Methods: Two point prevalence surveys were conducted in a convenience sample of 24 acute care hospitals throughout Germany, and data of all screened adult inpatients with prescription of a systemic antibiotic at a given day (n=4310) were included in the study. For each QI, the following clinimetric properties were assessed: applicability, feasibility, performance, case mix stability and interobserver reliability.Results: Eighteen QIs were considered sufficiently feasible, applicable and reliable, and had adequate room for improvement. The finally selected QIs primarily cover antibiotic therapy of common infections (bloodstream infection, pneumonia and urinary tract infection), while two of the QIs each address surgical prophylaxis and general aspects of antibiotic administration.Conclusions: Practice tests may be important to test the suitability of consensus process-of-care QIs in the field of hospital ABS. The 18 selected QIs considered suitable enough for hospital ABS in this study should be regarded as priority QIs useful for internal quality control and assurance. More research and additional practice tests may be needed to confirm their suitability for external quality assessment schemes. [ABSTRACT FROM AUTHOR]

Published
2019
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28. KAMPI - Das Projekt zur Förderung evidenzbasierter Arzneimittelinformation in deutschen Krankenhausapotheken

Author

Gruber, Anne-Christine, Amann, Steffen, Mildner, Claudia, Querbach, Christiane, Schuhmacher, Carolin, Strobach, Dorothea, and Vetter-Kerkhoff, Cornelia

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund und Fragestellung: Der Bundesverband Deutscher Krankenhausapotheker (ADKA) fördert seit 04/2014 das Projekt „Krankenhausapotheker sorgen für medizinisch-pharmazeutische Information“ (KAMPI). Ziel des Projekts ist die Unterstützung evidenzbasierter Arzneimittelinformation[zum vollständigen Text gelangen Sie über die oben angegebene URL], Gemeinsam informiert entscheiden; 17. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin

Published
2016

29. KAMPI - Project to promote evidence-based drug information in German hospital pharmacies

Author

Gruber, Anne-Christine, Amann, Steffen, Mildner, Claudia, Querbach, Christiane, Schuhmacher, Carolin, Strobach, Dorothea, and Vetter-Kerkhoff, Cornelia

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Background: The German Society of Hospital Pharmacists (ADKA) established the project „KAMPI“ (Krankenhaus-Apotheker sorgen für Medizinisch-Pharmazeutische Information; Hospital pharmacists provide medical and pharmaceutical information) with a part-time pharmacist in April 2014 to[for full text, please go to the a.m. URL], 22. Jahrestagung der Gesellschaft für Arzneimittelanwendungsforschung und Arzneimittelepidemiologie

Published
2015
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