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Your search keyword '"Quella, Susan"' showing total 21 results
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21 results on '"Quella, Susan"'

1. Understanding and Overcoming the Challenges Related to Cardiovascular Trials Involving Patients with Kidney Disease

Author

Ishida, Julie H., primary, Chauhan, Cynthia, additional, Gillespie, Barbara, additional, Gruchalla, Ken, additional, McCullough, Peter A., additional, Quella, Susan, additional, Romero, Alain, additional, Rossignol, Patrick, additional, Wheeler, David C., additional, Malley, Meaghan A., additional, West, Melissa, additional, and Herzog, Charles A., additional

Published
2021
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2. Improving the Design of Future PCI Trials for Stable Coronary Artery Disease: JACC State-of-the-Art Review

Author

Marquis-Gravel, Guillaume, Moliterno, David J., Francis, Darrel P., Jüni, Peter, Rosenberg, Yves D., Claessen, Bimmer E., Mentz, Robert J., Mehran, Roxana, Cutlip, Donald E., Chauhan, Cynthia, Quella, Susan, Zannad, Faiez, and Goodman, Shaun G.

Subjects
Percutaneous Coronary Intervention, Research Design, Humans, Coronary Artery Disease, Quality Improvement, Article, Randomized Controlled Trials as Topic
Abstract

The role of percutaneous coronary interventions in addition to medical therapy for patients with stable coronary artery disease continues to be debated in routine clinical practice, despite more than 2 decades of randomized controlled trials. The residual uncertainty arises from particular challenges facing revascularization trials. Which endpoint do doctors care about, and which do patients care about? Which participants should be enrolled? What background medical therapy should we use? When is placebo control relevant? In this paper, we discuss how these questions can be approached and examine the merits and disadvantages of possible options. Engaging multiple stakeholders, including patients, researchers, regulators, and funders, to ensure the design elements are methodologically valid and clinically meaningful should be an aspirational goal in the development of future trials.

Published
2020

3. Improving the Design of Future PCI Trials for Stable Coronary Artery Disease

Author

Marquis-Gravel, Guillaume, primary, Moliterno, David J., additional, Francis, Darrel P., additional, Jüni, Peter, additional, Rosenberg, Yves D., additional, Claessen, Bimmer E., additional, Mentz, Robert J., additional, Mehran, Roxana, additional, Cutlip, Donald E., additional, Chauhan, Cynthia, additional, Quella, Susan, additional, Zannad, Faiez, additional, and Goodman, Shaun G., additional

Published
2020
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5. CONTRIBUTORS

Author

Aboagye, Eric O., primary, Adjei, Alex A., additional, Albright, Charles F., additional, Ameyaw, Margaret-Mary, additional, Arbuck, Susan G., additional, Bonner, James A., additional, Buolamwini, John K., additional, Celis, Esteban, additional, Eisenhauer, Elizabeth, additional, Galanis, Evanthia, additional, Huang, Pearl S., additional, Huang, Ying, additional, Hunsberger, Sally A, additional, Kaminski, James J., additional, Kelland, Lloyd R., additional, Korn, Edward L., additional, Kusnezow, W., additional, Markovic, Svetomir N., additional, Mcleod, Howard L., additional, Nees, M., additional, Ove, Roger, additional, Padhani, A.R., additional, Pazdur, Richard, additional, Pluda, James M., additional, Powers, Robert, additional, Price, Patricia M., additional, Quella, Susan, additional, Rubinstein, Larry V., additional, Sheikh, M. Saeed, additional, Siegel, Marshall M., additional, Wang, Hui, additional, Williams, Grant, additional, Wissel, Paul S., additional, Woodworth, C.D., additional, and Zhang, Ruiwen, additional

Published
2006
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6. Lack of effect of coumarin in women with lymphedema after treatment for breast cancer

Author

Loprinzi, Charles L., Kugler, John W., Sloan, Jeff A., Rooke, Thom W., Quella, Susan K., Novotny, Paul, Mowat, Rex B., Michalak, John C., Stella, Philip J., Levitt, Ralph, Tschetter, Loren K., and Windschitl, Harold

Subjects
Lymphedema -- Drug therapy, Coumarins -- Evaluation
Abstract

The anticoagulant drug coumarin is not effective in treating lymphedema of the arm in women who have been treated for breast cancer. Lymphedema occurs when fluid accumulates in the skin, which causes swelling. Researchers randomly assigned 140 women with lymphedema of the arm to take coumarin or a placebo twice a day for six months. After six and 12 months, there was no difference between the groups in the size of the arm, indicating that coumarin did not reduce the swelling. Six percent of the women taking coumarin developed liver toxicity.

Published
1999

8. Megestrol acetate for the prevention of hot flashes

Author

Loprinzi, Charles L., Michalak, John C., Quella, Susan K., O'Fallon, Judith R., Hatfield, Alan K., Nelimark, Robert A., Dose, Ann Marie, Fischer, Tammy, Johnson, Claudia, Klatt, Nancy E., Bate, Walter W., Rospond, Raylene M., and Oesterling, Joseph E.

Subjects
Menopause -- Drug therapy, Megestrol acetate -- Health aspects, Hormone therapy -- Evaluation
Abstract

Megestrol acetate may be useful for reducing the frequency of hot flashes among men and women. It may be provide similar benefits to estrogen-replacement therapy in women, but without the unwanted side effect of stimulating tumor growth in women who have had breast cancer. Megestrol acetate may reduce the occurrence of hot flashes in men who have had androgen-deprivation therapy for prostate cancer. Low doses of megestrol acetate may be both well-tolerated and effective. A study of 97 women with histories of breast cancer and 66 men with prostate cancer found that low doses of megestrol acetate lowered the daily incidence of hot flashes a few weeks after therapy began. Possible side effects such as the effect of low doses of megestrol acetate on the growth of tumors in the breast, endometrium, and prostate are not known. It also is not known whether prolonged use of megestrol acetate may lead to thromboembolic disease.

Published
1994

18. SPECIAL DEPARTMENTS

Author

This, Pascale, primary, Magdelenat, Henri, additional, Loprinzi, Charles L., additional, Quella, Susan K., additional, and Barton, Debra L., additional

Published
2000
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20. Megestrol Acetate for the Prevention of Hot Flashes

Author

Loprinzi, Charles L., primary, Michalak, John C., additional, Quella, Susan K., additional, O'Fallon, Judith R., additional, Hatfield, Alan K., additional, Nelimark, Robert A., additional, Dose, Ann Marie, additional, Fischer, Tammy, additional, Johnson, Claudia, additional, Klatt, Nancy E., additional, Bate, Walter W., additional, Rospond, Raylene M., additional, and Oesterling, Joseph E., additional

Published
1995
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21. Transdermal Clonidine for Ameliorating Post-Orchiectomy Hot Flashes

Author

Loprinzi, Charles L., primary, Goldberg, Richard M., additional, O’Fallon, Judith R., additional, Quella, Susan K., additional, Miser, Angela W., additional, Mynderse, Lance A., additional, Brown, Loren D., additional, Tschetter, Loren K., additional, Wilwerding, Mary B., additional, Dose, Ann Marie, additional, and Oesterling, Joseph E., additional

Published
1994
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