31 results on '"Qian, Yijian"'
Search Results
2. Mortality and recurrent vascular events after first incident stroke: a 9-year community-based study of 0·5 million Chinese adults
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Chen, Yiping, Wright, Neil, Guo, Yu, Turnbull, Iain, Kartsonaki, Christiana, Yang, Ling, Bian, Zheng, Pei, Pei, Pan, Dongxia, Zhang, Yidan, Qin, Haiqiang, Wang, Yilong, Lv, Jun, Liu, Ming, Hao, Zilong, Wang, Yongjun, Yu, Canqing, Peto, Richard, Collins, Rory, Li, Liming, Clarke, Robert, Chen, Zhengming, Chen, Junshi, Walters, Robin, Avery, Daniel, Bennett, Derrick, Boxall, Ruth, Bragg, Fiona, Chang, Yumei, Du, Huaidong, Gilbert, Simon, Hacker, Alex, Holmes, Michael, Kerosi, Rene, Lancaster, Garry, Lin, Kuang, McDonnell, John, Millwood, Iona, Nie, Qunhua, Ryder, Paul, Sansome, Sam, Schmidt, Dan, Sohoni, Rajani, Wang, Jenny, Wang, Lin, Yang, Xiaoming, Han, Xiao, Hou, Can, Jing, Biao, Liu, Chao, Pang, Zengchang, Gao, Ruqin, Li, Shanpeng, Wang, Shaojie, Liu, Yongmei, Du, Ranran, Zang, Yajing, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Zhai, Yaoming, Ning, Feng, Sun, Xiaohui, Li, Feifei, Lv, Silu, Wang, Junzheng, Hou, Wei, Zeng, Mingyuan, Jiang, Ge, Zhou, Xue, Yang, Liqiu, He, Hui, Yu, Bo, Li, Yanjie, Xu, Qinai, Kang, Quan, Guo, Ziyan, Wang, Dan, Hu, Ximin, Wang, Hongmei, Chen, Jinyan, Fu, Yan, Fu, Zhenwang, Wang, Xiaohuan, Weng, Min, Guo, Zhendong, Wu, Shukuan, Li, Yilei, Li, Huimei, Fu, Zhifang, Wu, Ming, Zhou, Yonglin, Zhou, Jinyi, Tao, Ran, Yang, Jie, Su, Jian, Liu, Fang, Zhang, Jun, Hu, Yihe, Lu, Yan, Ma, Liangcai, Tang, Aiyu, Zhang, Shuo, Jin, Jianrong, Liu, Jingchao, Tang, Zhenzhu, Chen, Naying, Huang, Ying, Li, Mingqiang, Meng, Jinhuai, Pan, Rong, Jiang, Qilian, Lan, Jian, Liu, Yun, Wei, Liuping, Chen, Ningyu, Wang, Ping, Meng, Fanwen, Qin, Yulu, Wang, Sisi, Wu, Xianping, Zhang, Ningmei, Chen, Xiaofang, Zhou, Weiwei, Luo, Guojin, Li, Jianguo, Zhong, Xunfu, Liu, Jiaqiu, Sun, Qiang, Ge, Pengfei, Ren, Xiaolan, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Zhang, Ding, Zhou, Gang, Feng, Shixian, Chang, Liang, Fan, Lei, Gao, Yulian, He, Tianyou, Sun, Huarong, He, Pan, Hu, Chen, Zhang, Xukui, Wu, Huifang, Yu, Min, Hu, Ruying, Wang, Hao, Qian, Yijian, Wang, Chunmei, Xie, Kaixu, Chen, Lingli, Fu, Zhongxi, Xu, Qiaohua, Xu, Xin, Zhang, Hao, Long, Huajun, Li, Xianzhi, Zhang, Libo, and Qiu, Zhe
- Published
- 2020
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3. Cooking fuels and risk of all-cause and cardiopulmonary mortality in urban China: a prospective cohort study
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Chen, Junshi, Chen, Zhengming, Clarke, Robert, Collins, Rory, Guo, Yu, Li, Liming, Lv, Jun, Peto, Richard, Walters, Robin, Avery, Daniel, Boxall, Ruth, Chang, Yumei, Chen, Yiping, Du, Huaidong, Gilbert, Simon, Hacker, Alex, Hill, Mike, Holmes, Michael, Iona, Andri, Kartsonaki, Christiana, Kerosi, Rene, Kong, Ling, Kurmi, Om, Lancaster, Garry, Lewington, Sarah, Lin, Kuang, McDonnell, John, Millwood, Iona, Nie, Qunhua, Radhakrishnan, Jayakrishnan, Ryder, Paul, Sansome, Sam, Schmidt, Dan, Sherliker, Paul, Sohoni, Rajani, Stevens, Becky, Turnbull, Iain, Wang, Jenny, Wang, Lin, Wright, Neil, Yang, Ling, Yang, Xiaoming, Bian, Zheng, Han, Xiao, Hou, Can, Pei, Pei, Liu, Chao, Tan, Yunlong, Yu, Canqing, Pang, Zengchang, Gao, Ruqin, Li, Shanpeng, Wang, Shaojie, Liu, Yongmei, Du, Ranran, Zang, Yajing, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Zhai, Yaoming, Ning, Feng, Sun, Xiaohui, Li, Feifei, Lv, Silu, Wang, Junzheng, Hou, Wei, Zeng, Mingyuan, Jiang, Ge, Zhou, Xue, Yang, Liqiu, He, Hui, Yu, Bo, Li, Yanjie, Xu, Qinai, Kang, Quan, Guo, Ziyan, Wang, Dan, Hu, Ximin, Wang, Hongmei, Chen, Jinyan, Fu, Yan, Fu, Zhenwang, Wang, Xiaohuan, Weng, Min, Guo, Zhendong, Wu, Shukuan, Li, Yilei, Li, Huimei, Fu, Zhifang, Wu, Ming, Zhou, Yonglin, Zhou, Jinyi, Tao, Ran, Yang, Jie, Su, Jian, Liu, Fang, Zhang, Jun, Hu, Yihe, Lu, Yan, Ma, Liangcai, Tang, Aiyu, Zhang, Shuo, Jin, Jianrong, Liu, Jingchao, Tang, Zhenzhu, Chen, Naying, Huang, Ying, Li, Mingqiang, Meng, Jinhuai, Pan, Rong, Jiang, Qilian, Lan, Jian, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Chen, Ningyu, Wang, Ping, Meng, Fanwen, Qin, Yulu, Wang, Sisi, Wu, Xianping, Zhang, Ningmei, Chen, Xiaofang, Zhou, Weiwei, Luo, Guojin, Li, Jianguo, Zhong, Xunfu, Liu, Jiaqiu, Sun, Qiang, Ge, Pengfei, Ren, Xiaolan, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Zhang, Ding, Zhou, Gang, Feng, Shixian, Chang, Liang, Fan, Lei, Gao, Yulian, He, Tianyou, Sun, Huarong, He, Pan, Hu, Chen, Zhang, Xukui, Wu, Huifang, Yu, Min, Hu, Ruying, Wang, Hao, Qian, Yijian, Wang, Chunmei, Xie, Kaixu, Chen, Lingli, Zhang, Yidan, Pan, Dongxia, Gu, Qijun, Huang, Yuelong, Chen, Biyun, Yin, Li, Liu, Huilin, Fu, Zhongxi, Xu, Qiaohua, Xu, Xin, Zhang, Hao, Long, Huajun, Li, Xianzhi, Zhang, Libo, Qiu, Zhe, Yu, Kuai, Qiu, Gaokun, Wang, Chaolong, Pan, An, Liang, Liming, Hu, Frank B, and Wu, Tangchun
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- 2020
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4. Adiposity and risk of ischaemic and haemorrhagic stroke in 0·5 million Chinese men and women: a prospective cohort study
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Chen, Junshi, Chen, Zhengming, Clarke, Robert, Collins, Rory, Guo, Yu, Li, Liming, Lv, Jun, Peto, Richard, Walters, Robin, Avery, Daniel, Bennett, Derrick, Boxall, Ruth, Bragg, Fiona, Chang, Yumei, Chen, Yiping, Du, Huaidong, Gilbert, Simon, Hacker, Alex, Holmes, Michael, Iona, Andri, Kartsonaki, Christiana, Kerosi, Rene, Kurmi, Om, Lewington, Sarah, Lancaster, Garry, Lin, Kuang, McDonnell, John, Millwood, Iona, Nie, Qunhua, Radhakrishnan, Jayakrishnan, Ryder, Paul, Sansome, Sam, Schmidt, Dan, Sherliker, Paul, Sohoni, Rajani, Stevens, Becky, Turnbull, Iain, Wang, Jenny, Wang, Lin, Wright, Neil, Yang, Ling, Yang, Xiaoming, Bian, Zheng, Chen, Ge, Han, Xiao, Hou, Can, Pei, Pei, Qu, Shuzhen, Tan, Yunlong, Yu, Canqing, Pang, Zengchang, Gao, Ruqin, Wang, Shaojie, Liu, Yongmei, Du, Ranran, Zang, Yajing, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Lv, Silu, Wang, Junzheng, Hou, Wei, Yin, Jiyuan, Jiang, Ge, Zhou, Xue, Yang, Liqiu, He, Hui, Yu, Bo, Li, Yanjie, Mu, Huaiyi, Xu, Qinai, Dou, Meiling, Ren, Jiaojiao, Wang, Shanqing, Hu, Ximin, Wang, Hongmei, Chen, Jinyan, Fu, Yan, Fu, Zhenwang, Wang, Xiaohuan, Weng, Min, Zheng, Xiangyang, Li, Yilei, Li, Huimei, Wang, Yanjun, Wu, Ming, Zhou, Jinyi, Tao, Ran, Yang, Jie, Ni, Chuanming, Zhang, Jun, Hu, Yihe, Lu, Yan, Ma, Liangcai, Tang, Aiyu, Zhang, Shuo, Jin, Jianrong, Liu, Jingchao, Tang, Zhenzhu, Chen, Naying, Huang, Ying, Li, Mingqiang, Meng, Jinhuai, Pan, Rong, Jiang, Qilian, Zhang, Weiyuan, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Chen, Ningyu, Guan, Hairong, Wu, Xianping, Zhang, Ningmei, Chen, Xiaofang, Tang, Xuefeng, Luo, Guojin, Li, Jianguo, Zhong, Xunfu, Liu, Jiaqiu, Sun, Qiang, Ge, Pengfei, Ren, Xiaolan, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Zhang, Ding, Zhou, Gang, Feng, Shixian, Chang, Liang, Fan, Lei, Gao, Yulian, He, Tianyou, Sun, Huarong, He, Pan, Hu, Chen, Lv, Qiannan, Zhang, Xukui, Yu, Min, Hu, Ruying, Wang, Hao, Qian, Yijian, Wang, Chunmei, Xie, Kaixue, Chen, Lingli, Zhang, Yidan, Pan, Dongxia, Huang, Yuelong, Chen, Biyun, Yin, Li, Jin, Donghui, Liu, Huilin, Fu, Zhongxi, Xu, Qiaohua, Xu, Xin, Zhang, Hao, Xiong, Youping, Long, Huajun, Li, Xianzhi, Zhang, Libo, Qiu, Zhe, Parish, Sarah, Holmes, Michael V, Lacey, Ben, Liu, Fang, Zhang, Zengzhi, and Walters, Robin G
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- 2018
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5. Age-specific association between blood pressure and vascular and non-vascular chronic diseases in 0·5 million adults in China: a prospective cohort study
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Chen, Junshi, Chen, Zhengming, Clarke, Robert, Collins, Rory, Guo, Yu, Li, Liming, Lv, Jun, Peto, Richard, Walters, Robin, Avery, Daniel, Bennett, Derrick, Boxall, Ruth, Bragg, Fiona, Chang, Yumei, Chen, Yiping, Du, Huaidong, Gilbert, Simon, Hacker, Alex, Holmes, Michael, Iona, Andri, Kartsonaki, Christiana, Kerosi, Rene, Kurmi, Om, Lewington, Sarah, Lancaster, Garry, Lin, Kuang, McDonnell, John, Millwood, Iona, Nie, Qunhua, Radhakrishnan, Jayakrishnan, Ryder, Paul, Sansome, Sam, Schmidt, Dan, Sherliker, Paul, Sohoni, Rajani, Stevens, Becky, Turnbull, Iain, Wang, Jenny, Wang, Lin, Wright, Neil, Yang, Ling, Yang, Xiaoming, Bian, Zheng, Chen, Ge, Han, Xiao, Hou, Can, Pei, Pei, Qu, Shuzhen, Tan, Yunlong, Yu, Canqing, Pang, Zengchang, Gao, Ruqin, Wang, Shaojie, Liu, Yongmei, Du, Ranran, Zang, Yajing, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Lv, Silu, Wang, Junzheng, Hou, Wei, Yin, Jiyuan, Jiang, Ge, Zhou, Xue, Yang, Liqiu, He, Hui, Yu, Bo, Li, Yanjie, Mu, Huaiyi, Xu, Qinai, Dou, Meiling, Ren, Jiaojiao, Wang, Shanqing, Hu, Ximin, Wang, Hongmei, Chen, Jinyan, Fu, Yan, Fu, Zhenwang, Wang, Xiaohuan, Weng, Min, Zheng, Xiangyang, Li, Yilei, Li, Huimei, Wang, Yanjun, Wu, Ming, Zhou, Jinyi, Tao, Ran, Yang, Jie, Ni, Chuanming, Zhang, Jun, Hu, Yihe, Lu, Yan, Ma, Liangcai, Tang, Aiyu, Zhang, Shuo, Jin, Jianrong, Liu, Jingchao, Tang, Zhenzhu, Chen, Naying, Huang, Ying, Li, Mingqiang, Meng, Jinhuai, Pan, Rong, Jiang, Qilian, Zhang, Weiyuan, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Chen, Ningyu, Guan, Hairong, Wu, Xianping, Zhang, Ningmei, Chen, Xiaofang, Tang, Xuefeng, Luo, Guojin, Li, Jianguo, Zhong, Xunfu, Liu, Jiaqiu, Sun, Qiang, Ge, Pengfei, Ren, Xiaolan, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Zhang, Ding, Zhou, Gang, Feng, Shixian, Chang, Liang, Fan, Lei, Gao, Yulian, He, Tianyou, Sun, Huarong, He, Pan, Hu, Chen, Lv, Qiannan, Zhang, Xukui, Yu, Min, Hu, Ruying, Wang, Hao, Qian, Yijian, Wang, Chunmei, Xie, Kaixue, Chen, Lingli, Zhang, Yidan, Pan, Dongxia, Huang, Yuelong, Chen, Biyun, Yin, Li, Jin, Donghui, Liu, Huilin, Fu, Zhongxi, Xu, Qiaohua, Xu, Xin, Zhang, Hao, Xiong, Youping, Long, Huajun, Li, Xianzhi, Zhang, Libo, Qiu, Zhe, Lacey, Ben, Kong, Xiang Ling, and Walters, Robin G
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- 2018
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6. Smoking and smoking cessation in relation to risk of diabetes in Chinese men and women: a 9-year prospective study of 0·5 million people
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Chen, Junshi, Chen, Zhengming, Clarke, Robert, Collins, Rory, Guo, Yu, Li, Liming, Lv, Jun, Peto, Richard, Walters, Robin, Avery, Daniel, Bennett, Derrick, Boxall, Ruth, Bragg, Fiona, Chang, Yumei, Chen, Yiping, Du, Huaidong, Gilbert, Simon, Hacker, Alex, Holmes, Michael, Kartsonaki, Christiana, Kerosi, Rene, Lancaster, Garry, Lin, Kuang, McDonnell, John, Millwood, Iona, Nie, Qunhua, Radhakrishnan, Jayakrishnan, Ryder, Paul, Sansome, Sam, Schmidt, Dan, Sohoni, Rajani, Stevens, Becky, Turnbull, Iain, Wang, Jenny, Wang, Lin, Wright, Neil, Yang, Ling, Yang, Xiaoming, Bian, Zheng, Chen, Ge, Han, Xiao, Hou, Can, Pei, Pei, Qu, Shuzhen, Tan, Yunlong, Yu, Canqing, Pang, Zengchang, Gao, Ruqin, Wang, Shaojie, Liu, Yongmei, Du, Ranran, Zang, Yajing, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Lv, Silu, Wang, Junzheng, Hou, Wei, Yin, Jiyuan, Jiang, Ge, Zhou, Xue, Yang, Liqiu, He, Hui, Yu, Bo, Li, Yanjie, Mu, Huaiyi, Xu, Qinai, Dou, Meiling, Ren, Jiaojiao, Wang, Shanqing, Hu, Ximin, Wang, Hongmei, Chen, Jinyan, Fu, Yan, Fu, Zhenwang, Wang, Xiaohuan, Weng, Min, Zheng, Xiangyang, Li, Yilei, Li, Huimei, Wang, Yanjun, Wu, Ming, Zhou, Jinyi, Tao, Ran, Yang, Jie, Ni, Chuanming, Zhang, Jun, Hu, Yihe, Lu, Yan, Ma, Liangcai, Tang, Aiyu, Zhang, Shuo, Jin, Jianrong, Liu, Jingchao, Tang, Zhenzhu, Chen, Naying, Huang, Ying, Li, Mingqiang, Meng, Jinhuai, Pan, Rong, Jiang, Qilian, Zhang, Weiyuan, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Chen, Ningyu, Guan, Hairong, Wu, Xianping, Zhang, Ningmei, Chen, Xiaofang, Tang, Xuefeng, Luo, Guojin, Li, Jianguo, Zhong, Xunfu, Liu, Jiaqiu, Sun, Qiang, Ge, Pengfei, Ren, Xiaolan, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Zhang, Ding, Zhou, Gang, Feng, Shixian, Chang, Liang, Fan, Lei, Gao, Yulian, He, Tianyou, Sun, Huarong, He, Pan, Hu, Chen, Lv, Qiannan, Zhang, Xukui, Yu, Min, Hu, Ruying, Wang, Hao, Qian, Yijian, Wang, Chunmei, Xie, Kaixue, Chen, Lingli, Zhang, Yidan, Pan, Dongxia, Huang, Yuelong, Chen, Biyun, Yin, Li, Jin, Donghui, Liu, Huilin, Fu, Zhongxi, Xu, Qiaohua, Xu, Xin, Zhang, Hao, Xiong, Youping, Long, Huajun, Li, Xianzhi, Zhang, Libo, Qiu, Zhe, Liu, Xin, and Wang, Kang
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- 2018
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7. Risks of Stroke and Heart Disease Following Hysterectomy and Oophorectomy in Chinese Premenopausal Women
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Poorthuis, Michiel H.F., primary, Yao, Pang, additional, Chen, Yiping, additional, Guo, Yu, additional, Shi, Liya, additional, Li, Liming, additional, Chen, Zhengming, additional, Clarke, Robert, additional, Yang, Ling, additional, Chen, Junshi, additional, Collins, Rory, additional, Lv, Jun, additional, Peto, Richard, additional, Walters, Robin, additional, Avery, Daniel, additional, Bennett, Derrick, additional, Boxall, Ruth, additional, Bragg, Fiona, additional, Chang, Yumei, additional, Du, Huaidong, additional, Gilbert, Simon, additional, Hacker, Alex, additional, Holmes, Michael, additional, Kartsonaki, Christiana, additional, Kerosi, Rene, additional, Lin, Kuang, additional, Millwood, Iona, additional, Nie, Qunhua, additional, Ryder, Paul, additional, Sansome, Sam, additional, Schmidt, Dan, additional, Sohoni, Rajani, additional, Turnbull, Iain, additional, Wang, Lin, additional, Wright, Neil, additional, Yang, Xiaoming, additional, Han, Xiao, additional, Hou, Can, additional, Jing, Biao, additional, Liu, Chao, additional, Pei, Pei, additional, Tan, Yunlong, additional, Yu, Canqing, additional, Pang, Zengchang, additional, Gao, Ruqin, additional, Li, Shanpeng, additional, Wang, Shaojie, additional, Liu, Yongmei, additional, Du, Ranran, additional, Zang, Yajing, additional, Cheng, Liang, additional, Tian, Xiaocao, additional, Zhang, Hua, additional, Zhai, Yaoming, additional, Ning, Feng, additional, Sun, Xiaohui, additional, Li, Feifei, additional, Lv, Silu, additional, Wang, Junzheng, additional, Hou, Wei, additional, Zeng, Mingyuan, additional, Jiang, Ge, additional, Zhou, Xue, additional, Yang, Liqiu, additional, He, Hui, additional, Yu, Bo, additional, Li, Yanjie, additional, Xu, Qinai, additional, Kang, Quan, additional, Guo, Ziyan, additional, Wang, Dan, additional, Hu, Ximin, additional, Wang, Hongmei, additional, Chen, Jinyan, additional, Fu, Yan, additional, Fu, Zhenwang, additional, Wang, Xiaohuan, additional, Weng, Min, additional, Guo, Zhendong, additional, Wu, Shukuan, additional, Li, Yilei, additional, Li, Huimei, additional, Fu, Zhifang, additional, Wu, Ming, additional, Zhou, Yonglin, additional, Zhou, Jinyi, additional, Tao, Ran, additional, Yang, Jie, additional, Su, Jian, additional, Liu, Fang, additional, Zhang, Jun, additional, Hu, Yihe, additional, Lu, Yan, additional, Ma, Liangcai, additional, Tang, Aiyu, additional, Zhang, Shuo, additional, Jin, Jianrong, additional, Liu, Jingchao, additional, Tang, Zhenzhu, additional, Chen, Naying, additional, Huang, Ying, additional, Li, Mingqiang, additional, Meng, Jinhuai, additional, Pan, Rong, additional, Jiang, Qilian, additional, Lan, Jian, additional, Liu, Yun, additional, Wei, Liuping, additional, Zhou, Liyuan, additional, Chen, Ningyu, additional, Wang, Ping, additional, Meng, Fanwen, additional, Qin, Yulu, additional, Wang, Sisi, additional, Wu, Xianping, additional, Zhang, Ningmei, additional, Chen, Xiaofang, additional, Zhou, Weiwei, additional, Luo, Guojin, additional, Li, Jianguo, additional, Zhong, Xunfu, additional, Liu, Jiaqiu, additional, Sun, Qiang, additional, Ge, Pengfei, additional, Ren, Xiaolan, additional, Dong, Caixia, additional, Zhang, Hui, additional, Mao, Enke, additional, Wang, Xiaoping, additional, Wang, Tao, additional, Zhang, Xi, additional, Zhang, Ding, additional, Zhou, Gang, additional, Feng, Shixian, additional, Chang, Liang, additional, Fan, Lei, additional, Gao, Yulian, additional, He, Tianyou, additional, Sun, Huarong, additional, He, Pan, additional, Hu, Chen, additional, Zhang, Xukui, additional, Wu, Huifang, additional, Yu, Min, additional, Hu, Ruying, additional, Wang, Hao, additional, Qian, Yijian, additional, Wang, Chunmei, additional, Xie, Kaixu, additional, Chen, Lingli, additional, Zhang, Yidan, additional, Pan, Dongxia, additional, Gu, Qijun, additional, Huang, Yuelong, additional, Chen, Biyun, additional, Yin, Li, additional, Liu, Huilin, additional, Fu, Zhongxi, additional, Xu, Qiaohua, additional, Xu, Xin, additional, Zhang, Hao, additional, Long, Huajun, additional, Li, Xianzhi, additional, Zhang, Libo, additional, and Qiu, Zhe, additional
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- 2022
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8. A biomimetic metal–organic framework with cuboid inner cavities for enantioselective separation
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Zhu, Chengfeng, primary, Zhang, A-Mei, additional, Li, Ying, additional, Li, Han-Xue, additional, Qian, Yijian, additional, Fu, Yanming, additional, Wu, Xiang, additional, and Li, Yougui, additional
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- 2022
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9. Vitamin D and cause-specific vascular disease and mortality: a Mendelian randomisation study involving 99,012 Chinese and 106,911 European adults
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Huang, Tao, Afzal, Shoaib, Yu, Canqing, Guo, Yu, Bian, Zheng, Yang, Ling, Millwood, Iona Y., Walters, Robin G., Chen, Yiping, Chen, Ningyu, Gao, Ruqin, Chen, Junshi, Clarke, Robert, Chen, Zhengming, Ellervik, Christina, Nordestgaard, Børge G., Lv, Jun, Li, Liming, Collins, Rory, Peto, Richard, Avery, Daniel, Boxall, Ruth, Bennett, Derrick, Chang, Yumei, Du, Huaidong, Gilbert, Simon, Hacker, Alex, Hill, Mike, Holmes, Michael, Iona, Andri, Kartsonaki, Christiana, Kerosi, Rene, Kong, Ling, Kurmi, Om, Lancaster, Garry, Lewington, Sarah, Lin, Kuang, McDonnell, John, Nie, Qunhua, Radhakrishnan, Jayakrishnan, Ryder, Paul, Sansome, Sam, Schmidt, Dan, Sherliker, Paul, Sohoni, Rajani, Stevens, Becky, Turnbull, Iain, Wang, Jenny, Wang, Lin, Wright, Neil, Yang, Xiaoming, Han, Xiao, Hou, Can, Pei, Pei, Liu, Chao, Tan, Yunlong, Pang, Zengchang, Li, Shanpeng, Wang, Shaojie, Liu, Yongmei, Du, Ranran, Zang, Yajing, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Zhai, Yaoming, Ning, Feng, Sun, Xiaohui, Li, Feifei, Lv, Silu, Wang, Junzheng, Hou, Wei, Zeng, Mingyuan, Jiang, Ge, Zhou, Xue, Yang, Liqiu, He, Hui, Yu, Bo, Li, Yanjie, Xu, Qinai, Kang, Quan, Guo, Ziyan, Wang, Dan, Hu, Ximin, Chen, Jinyan, Fu, Yan, Fu, Zhenwang, Wang, Xiaohuan, Weng, Min, Guo, Zhendong, Wu, Shukuan, Li, Yilei, Li, Huimei, Fu, Zhifang, Wu, Ming, Zhou, Yonglin, Zhou, Jinyi, Tao, Ran, Yang, Jie, Su, Jian, Liu, Fang, Zhang, Jun, Hu, Yihe, Lu, Yan, Ma, Liangcai, Tang, Aiyu, Zhang, Shuo, Jin, Jianrong, Liu, Jingchao, Tang, Zhenzhu, Chen, Naying, Huang, Ying, Li, Mingqiang, Meng, Jinhuai, Pan, Rong, Jiang, Qilian, Lan, Jian, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Wang, Ping, Meng, Fanwen, Qin, Yulu, Wang, Sisi, Wu, Xianping, Zhang, Ningmei, Zhou, Weiwei, Luo, Guojin, Li, Jianguo, Chen, Xiaofang, Zhong, Xunfu, Liu, Jiaqiu, Sun, Qiang, Ge, Pengfei, Ren, Xiaolan, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Zhang, Ding, Zhou, Gang, Feng, Shixian, Chang, Liang, Fan, Lei, Gao, Yulian, He, Tianyou, Sun, Huarong, Hu, Chen, Zhang, Xukui, Wu, Huifang, He, Pan, Yu, Min, Hu, Ruying, Wang, Hao, Qian, Yijian, Wang, Chunmei, Xie, Kaixu, Chen, Lingli, Zhang, Yidan, Pan, Dongxia, Gu, Qijun, Huang, Yuelong, Chen, Biyun, Yin, Li, Liu, Huilin, Fu, Zhongxi, Xu, Qiaohua, Xu, Xin, Zhang, Hao, Long, Huajun, Li, Xianzhi, Zhang, Libo, and Qiu, Zhe
- Subjects
Adult ,medicine.medical_specialty ,lcsh:Medicine ,Disease ,Lower risk ,Gastroenterology ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Causal effect ,Vitamin D and neurology ,Humans ,Medicine ,Vascular Diseases ,030212 general & internal medicine ,Myocardial infarction ,Vitamin D ,Mendelian randomisation ,Stroke ,business.industry ,Vascular disease ,Confounding ,lcsh:R ,General Medicine ,Vitamin D Deficiency ,medicine.disease ,Lipids ,3. Good health ,Cardiovascular diseases ,Population study ,Gene-Environment Interaction ,business ,030217 neurology & neurosurgery ,Research Article - Abstract
Background Randomised control trials and genetic analyses have demonstrated that vitamin D or 25-hydroxyvitamin D (25[OH]D) levels may not play a causal role in the development of cardiovascular disease. However, it is unclear if 25(OH)D is causally associated with cause-specific vascular disease and lipids. Therefore, we examined the causal association of 25(OH)D with myocardial infarction, stroke, ischaemic heart disease, ischaemic stroke, subarachnoid haemorrhage, intracerebral haemorrhage, and lipid levels among both Chinese and Europeans. Methods We used a Mendelian randomisation (MR) design in the China Kadoorie Biobank, the Copenhagen City Heart Study, and the Copenhagen General Population Study. The 25(OH)D-related genetic variants in the CYP2R1 and DCHR7 genes were genotyped in 99,012 Chinese adults and 106,911 Danish adults. Results In Chinese adults, plasma 25(OH)D levels were not significantly associated with cause-specific vascular disease or mortality, with the exception of intracerebral haemorrhage (HR, 1.09 [95% CI, 1.01,1.18] per 25 nmol/L higher plasma 25(OH)D). In Europeans, plasma 25(OH)D levels were inversely associated with all types of vascular diseases and mortality. However, MR analysis did not demonstrate causal associations of genetically increased 25(OH)D levels with cause-specific vascular diseases, or mortality in both Chinese and European adults. In addition, each 25 nmol/L higher 25(OH)D was observationally associated with lower total cholesterol and low-density lipoprotein cholesterol levels, but higher high-density lipoprotein cholesterol levels. Likewise, MR analysis showed that 25(OH)D levels were not causally associated with lipids in both Chinese and European adults after Bonferroni correction. Conclusions We found no evidence to support that genetically increased 25(OH)D was associated with a lower risk of ischaemic stroke, intracerebral haemorrhage, subarachnoid haemorrhage, and lipid levels in both Chinese and European adults. These results suggest that the inverse associations of vitamin D with vascular disease could be the result of confounding. Electronic supplementary material The online version of this article (10.1186/s12916-019-1401-y) contains supplementary material, which is available to authorized users.
- Published
- 2019
10. Outdoor temperature, blood pressure, and cardiovascular disease mortality among 23 000 individuals with diagnosed cardiovascular diseases from China
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Yang, Ling, Li, Liming, Lewington, Sarah, Guo, Yu, Sherliker, Paul, Bian, Zheng, Collins, Rory, Peto, Richard, Liu, Yun, Yang, Rong, Zhang, Yongrui, Li, Guangchun, Liu, Shumei, Chen, Zhengming, Li, Liming, Chen, Junshi, Collins, Rory, Peto, Richard, Chen, Zhengming, Chen, Zhengming, Lancaster, Garry, Yang, Xiaoming, Williams, Alex, Smith, Margaret, Yang, Ling, Chang, Yumei, Millwood, Iona, Chen, Yiping, Lewington, Sarah, Guo, Yu, Bian, Zheng, Hou, Can, Tan, Yunlong, Zhou, Huiyan, Pang, Zengchang, Wang, Shaojie, Zhang, Yun, Zhang, Kui, Liu, Silu, Hou, Wei, Zhao, Zhonghou, Liu, Shumei, Pang, Zhigang, Feng, Weijia, Wu, Shuling, Yang, Liqiu, Han, Huili, He, Hui, Yu, Bo, Pan, Xianhai, Wang, Shanqing, Wang, Hongmei, Hao, Xinhua, Chen, Chunxing, Lin, Shuxiong, Zheng, Xiangyang, Hu, Xiaoshu, Zhou, Minghao, Wu, Ming, Tao, Ran, Wang, Yeyuan, Hu, Yihe, Ma, Liangcai, Zhou, Renxian, Xu, Guanqun, Lu, Yan, Dong, Baiqing, Chen, Naying, Huang, Ying, Li, Mingqiang, Meng, Jinhuai, Gan, Zhigao, Xu, Jiujiu, Liu, Yun, Qing, Jingxin, Wu, Xianping, Gao, Yali, Luo, Guojin, Que, Xiangsan, Chen, Xiaofang, Ge, Pengfei, He, Jian, Ren, Xiaolan, Zhang, Hui, Mao, Enke, Li, Guanzhong, Li, Zhongxiao, He, Jun, Lei, Yulong, Wang, Xiaoping, Liu, Guohua, Zhu, Baoyu, Zhou, Gang, Feng, Shixian, Gao, Yulian, He, Tianyou, Jiang, Li, Qin, Jianhua, Sun, Huarong, Liu, Liqun, Yu, Min, Chen, Yaping, Hu, Ruying, Hu, Zhixiang, Hu, Jianjin, Qian, Yijian, Wu, Zhiying, Wang, Chunmei, Chen, Lingli, Liu, Wen, Li, Guangchun, Liu, Huilin, Long, Xiangquan, Xu, Xin, Xiong, Youping, Tan, Zhongwen, Xie, Xuqiu, Peng, Yunfang, and Jia, Weifang
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- 2015
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11. Season and outdoor temperature in relation to detection and control of hypertension in a large rural Chinese population
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Su, Danting, Du, Huaidong, Zhang, Xinwei, Qian, Yijian, Chen, Lingli, Chen, Yaping, Guo, Yu, Bian, Zheng, Chen, Zhengming, Li, Liming, and Yu, Min
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- 2014
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12. Association of heart rate and diabetes among 0.5 million adults in the China Kadoorie biobank: Results from observational and Mendelian randomization analyses
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Wang, Wenxiu, primary, Wang, Jingjia, additional, Lv, Jun, additional, Yu, Canqing, additional, Shao, Chunli, additional, Tang, Yida, additional, Guo, Yu, additional, Bian, Zheng, additional, Du, Huaidong, additional, Yang, Ling, additional, Millwood, Iona Y., additional, Walters, Robin G., additional, Chen, Yiping, additional, Chang, Liang, additional, Fan, Lei, additional, Chen, Junshi, additional, Chen, Zhengming, additional, Huang, Tao, additional, Li, Liming, additional, Clarke, Robert, additional, Collins, Rory, additional, Peto, Richard, additional, Walters, Robin, additional, Avery, Daniel, additional, Boxall, Ruth, additional, Bennett, Derrick, additional, Chang, Yumei, additional, Gilbert, Simon, additional, Hacker, Alex, additional, Hill, Mike, additional, Holmes, Michael, additional, Iona, Andri, additional, Kartsonaki, Christiana, additional, Kerosi, Rene, additional, Kong, Ling, additional, Kurmi, Om, additional, Lancaster, Garry, additional, Lewington, Sarah, additional, Lin, Kuang, additional, McDonnell, John, additional, Millwood, Iona, additional, Nie, Qunhua, additional, Radhakrishnan, Jayakrishnan, additional, Ryder, Paul, additional, Sansome, Sam, additional, Schmidt, Dan, additional, Sherliker, Paul, additional, Sohoni, Rajani, additional, Stevens, Becky, additional, Turnbull, Iain, additional, Wang, Jenny, additional, Wang, Lin, additional, Wright, Neil, additional, Yang, Xiaoming, additional, Han, Xiao, additional, Hou, Can, additional, Pei, Pei, additional, Liu, Chao, additional, Tan, Yunlong, additional, Pang, Zengchang, additional, Gao, Ruqin, additional, Li, Shanpeng, additional, Wang, Shaojie, additional, Liu, Yongmei, additional, Du, Ranran, additional, Zang, Yajing, additional, Cheng, Liang, additional, Tian, Xiaocao, additional, Zhang, Hua, additional, Zhai, Yaoming, additional, Ning, Feng, additional, Sun, Xiaohui, additional, Li, Feifei, additional, Lv, Silu, additional, Wang, Junzheng, additional, Hou, Wei, additional, Zeng, Mingyuan, additional, Jiang, Ge, additional, Zhou, Xue, additional, Yang, Liqiu, additional, He, Hui, additional, Yu, Bo, additional, Li, Yanjie, additional, Xu, Qinai, additional, Kang, Quan, additional, Guo, Ziyan, additional, Wang, Dan, additional, Hu, Ximin, additional, Chen, Jinyan, additional, Fu, Yan, additional, Fu, Zhenwang, additional, Wang, Xiaohuan, additional, Weng, Min, additional, Guo, Zhendong, additional, Wu, Shukuan, additional, Li, Yilei, additional, Li, Huimei, additional, Fu, Zhifang, additional, Wu, Ming, additional, Zhou, Yonglin, additional, Zhou, Jinyi, additional, Tao, Ran, additional, Yang, Jie, additional, Su, Jian, additional, liu, Fang, additional, Zhang, Jun, additional, Hu, Yihe, additional, Lu, Yan, additional, Ma, Liangcai, additional, Tang, Aiyu, additional, Zhang, Shuo, additional, Jin, Jianrong, additional, Liu, Jingchao, additional, Tang, Zhenzhu, additional, Chen, Naying, additional, Huang, Ying, additional, Li, Mingqiang, additional, Meng, Jinhuai, additional, Pan, Rong, additional, Jiang, Qilian, additional, Lan, Jian, additional, Liu, Yun, additional, Wei, Liuping, additional, Zhou, Liyuan, additional, Ping Wang, Ningyu Chen, additional, Meng, Fanwen, additional, Qin, Yulu, additional, Wang, Sisi, additional, Wu, Xianping, additional, Zhang, Ningmei, additional, Chen, Xiaofang, additional, Zhou, Weiwei, additional, Luo, Guojin, additional, Li, Jianguo, additional, Zhong, Xunfu, additional, Liu, Jiaqiu, additional, Sun, Qiang, additional, Ge, Pengfei, additional, Ren, Xiaolan, additional, Dong, Caixia, additional, Zhang, Hui, additional, Mao, Enke, additional, Wang, Xiaoping, additional, Wang, Tao, additional, zhang, Xi, additional, Zhang, Ding, additional, Zhou, Gang, additional, Feng, Shixian, additional, Gao, Yulian, additional, He, Tianyou, additional, Sun, Huarong, additional, He, Pan, additional, Hu, Chen, additional, Zhang, Xukui, additional, Wu, Huifang, additional, Yu, Min, additional, Hu, Ruying, additional, Wang, Hao, additional, Qian, Yijian, additional, Wang, Chunmei, additional, Xie, Kaixu, additional, Chen, Lingli, additional, Zhang, Yidan, additional, Pan, Dongxia, additional, Gu, Qijun, additional, Huang, Yuelong, additional, Chen, Biyun, additional, Yin, Li, additional, Liu, Huilin, additional, Fu, Zhongxi, additional, Xu, Qiaohua, additional, Xu, Xin, additional, Zhang, Hao, additional, Long, Huajun, additional, Li, Xianzhi, additional, Zhang, Libo, additional, and Qiu, Zhe, additional
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- 2021
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13. Alcohol consumption in 0.5 million people from 10 diverse regions of China: prevalence, patterns and socio-demographic and health-related correlates
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Millwood, Iona Y, Li, Liming, Smith, Margaret, Guo, Yu, Yang, Ling, Bian, Zheng, Lewington, Sarah, Whitlock, Gary, Sherliker, Paul, Collins, Rory, Chen, Junshi, Peto, Richard, Wang, Hongmei, Xu, Jiujiu, He, Jian, Yu, Min, Liu, Huilin, Chen, Zhengming, Li, Liming, Chen, Zhengming, Chen, Junshi, Collins, Rory, Wu, Fan, Peto, Richard, Chen, Zhengming, Lancaster, Garry, Yang, Xiaoming, Williams, Alex, Smith, Margaret, Yang, Ling, Chang, Yumei, Millwood, Iona, Chen, Yiping, Zhang, Qiuli, Lewington, Sarah, Whitlock, Gary, Guo, Yu, Zhao, Guoqing, Bian, Zheng, Wu, Lixue, Hou, Can, Pang, Zengchang, Wang, Shaojie, Zhang, Yun, Zhang, Kui, Liu, Silu, Zhao, Zhonghou, Liu, Shumei, Pang, Zhigang, Feng, Weijia, Wu, Shuling, Yang, Liqiu, Han, Huili, He, Hui, Pan, Xianhai, Wang, Shanqing, Wang, Hongmei, Hao, Xinhua, Chen, Chunxing, Lin, Shuxiong, Hu, Xiaoshu, Zhou, Minghao, Wu, Ming, Wang, Yeyuan, Hu, Yihe, Ma, Liangcai, Zhou, Renxian, Xu, Guanqun, Dong, Baiqing, Chen, Naying, Huang, Ying, Li, Mingqiang, Meng, Jinhuai, Gan, Zhigao, Xu, Jiujiu, Liu, Yun, Wu, Xianping, Gao, Yali, Zhang, Ningmei, Luo, Guojin, Que, Xiangsan, Chen, Xiaofang, Ge, Pengfei, He, Jian, Ren, Xiaolan, Zhang, Hui, Mao, Enke, Li, Guanzhong, Li, Zhongxiao, He, Jun, Liu, Guohua, Zhu, Baoyu, Zhou, Gang, Feng, Shixian, Gao, Yulian, He, Tianyou, Jiang, Li, Qin, Jianhua, Sun, Huarong, Liu, Liqun, Yu, Min, Chen, Yaping, Hu, Zhixiang, Hu, Jianjin, Qian, Yijian, Wu, Zhiying, Chen, Lingli, Liu, Wen, Li, Guangchun, Liu, Huilin, Long, Xiangquan, Xiong, Youping, Tan, Zhongwen, Xie, Xuqiu, and Peng, Yunfang
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- 2013
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14. Cooking fuels and risk of all-cause and cardiopulmonary mortality in urban China: a prospective cohort study
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Yu, Kuai, primary, Lv, Jun, additional, Qiu, Gaokun, additional, Yu, Canqing, additional, Guo, Yu, additional, Bian, Zheng, additional, Yang, Ling, additional, Chen, Yiping, additional, Wang, Chaolong, additional, Pan, An, additional, Liang, Liming, additional, Hu, Frank B, additional, Chen, Zhengming, additional, Li, Liming, additional, Wu, Tangchun, additional, Chen, Junshi, additional, Clarke, Robert, additional, Collins, Rory, additional, Peto, Richard, additional, Walters, Robin, additional, Avery, Daniel, additional, Boxall, Ruth, additional, Chang, Yumei, additional, Du, Huaidong, additional, Gilbert, Simon, additional, Hacker, Alex, additional, Hill, Mike, additional, Holmes, Michael, additional, Iona, Andri, additional, Kartsonaki, Christiana, additional, Kerosi, Rene, additional, Kong, Ling, additional, Kurmi, Om, additional, Lancaster, Garry, additional, Lewington, Sarah, additional, Lin, Kuang, additional, McDonnell, John, additional, Millwood, Iona, additional, Nie, Qunhua, additional, Radhakrishnan, Jayakrishnan, additional, Ryder, Paul, additional, Sansome, Sam, additional, Schmidt, Dan, additional, Sherliker, Paul, additional, Sohoni, Rajani, additional, Stevens, Becky, additional, Turnbull, Iain, additional, Wang, Jenny, additional, Wang, Lin, additional, Wright, Neil, additional, Yang, Xiaoming, additional, Han, Xiao, additional, Hou, Can, additional, Pei, Pei, additional, Liu, Chao, additional, Tan, Yunlong, additional, Pang, Zengchang, additional, Gao, Ruqin, additional, Li, Shanpeng, additional, Wang, Shaojie, additional, Liu, Yongmei, additional, Du, Ranran, additional, Zang, Yajing, additional, Cheng, Liang, additional, Tian, Xiaocao, additional, Zhang, Hua, additional, Zhai, Yaoming, additional, Ning, Feng, additional, Sun, Xiaohui, additional, Li, Feifei, additional, Lv, Silu, additional, Wang, Junzheng, additional, Hou, Wei, additional, Zeng, Mingyuan, additional, Jiang, Ge, additional, Zhou, Xue, additional, Yang, Liqiu, additional, He, Hui, additional, Yu, Bo, additional, Li, Yanjie, additional, Xu, Qinai, additional, Kang, Quan, additional, Guo, Ziyan, additional, Wang, Dan, additional, Hu, Ximin, additional, Wang, Hongmei, additional, Chen, Jinyan, additional, Fu, Yan, additional, Fu, Zhenwang, additional, Wang, Xiaohuan, additional, Weng, Min, additional, Guo, Zhendong, additional, Wu, Shukuan, additional, Li, Yilei, additional, Li, Huimei, additional, Fu, Zhifang, additional, Wu, Ming, additional, Zhou, Yonglin, additional, Zhou, Jinyi, additional, Tao, Ran, additional, Yang, Jie, additional, Su, Jian, additional, Liu, Fang, additional, Zhang, Jun, additional, Hu, Yihe, additional, Lu, Yan, additional, Ma, Liangcai, additional, Tang, Aiyu, additional, Zhang, Shuo, additional, Jin, Jianrong, additional, Liu, Jingchao, additional, Tang, Zhenzhu, additional, Chen, Naying, additional, Huang, Ying, additional, Li, Mingqiang, additional, Meng, Jinhuai, additional, Pan, Rong, additional, Jiang, Qilian, additional, Lan, Jian, additional, Liu, Yun, additional, Wei, Liuping, additional, Zhou, Liyuan, additional, Chen, Ningyu, additional, Wang, Ping, additional, Meng, Fanwen, additional, Qin, Yulu, additional, Wang, Sisi, additional, Wu, Xianping, additional, Zhang, Ningmei, additional, Chen, Xiaofang, additional, Zhou, Weiwei, additional, Luo, Guojin, additional, Li, Jianguo, additional, Zhong, Xunfu, additional, Liu, Jiaqiu, additional, Sun, Qiang, additional, Ge, Pengfei, additional, Ren, Xiaolan, additional, Dong, Caixia, additional, Zhang, Hui, additional, Mao, Enke, additional, Wang, Xiaoping, additional, Wang, Tao, additional, Zhang, Xi, additional, Zhang, Ding, additional, Zhou, Gang, additional, Feng, Shixian, additional, Chang, Liang, additional, Fan, Lei, additional, Gao, Yulian, additional, He, Tianyou, additional, Sun, Huarong, additional, He, Pan, additional, Hu, Chen, additional, Zhang, Xukui, additional, Wu, Huifang, additional, Yu, Min, additional, Hu, Ruying, additional, Wang, Hao, additional, Qian, Yijian, additional, Wang, Chunmei, additional, Xie, Kaixu, additional, Chen, Lingli, additional, Zhang, Yidan, additional, Pan, Dongxia, additional, Gu, Qijun, additional, Huang, Yuelong, additional, Chen, Biyun, additional, Yin, Li, additional, Liu, Huilin, additional, Fu, Zhongxi, additional, Xu, Qiaohua, additional, Xu, Xin, additional, Zhang, Hao, additional, Long, Huajun, additional, Li, Xianzhi, additional, Zhang, Libo, additional, and Qiu, Zhe, additional
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- 2020
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15. Vitamin D and cause-specific vascular disease and mortality:a Mendelian randomisation study involving 99,012 Chinese and 106,911 European adults
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Huang, Tao, Afzal, Shoaib, Yu, Canqing, Guo, Yu, Bian, Zheng, Yang, Ling, Millwood, Iona Y., Walters, Robin G., Chen, Yiping, Chen, Ningyu, Gao, Ruqin, Chen, Junshi, Clarke, Robert, Chen, Zhengming, Ellervik, Christina, Nordestgaard, Børge G., Lv, Jun, Li, Liming, Collins, Rory, Peto, Richard, Avery, Daniel, Boxall, Ruth, Bennett, Derrick, Chang, Yumei, Du, Huaidong, Gilbert, Simon, Hacker, Alex, Hill, Mike, Holmes, Michael, Iona, Andri, Kartsonaki, Christiana, Kerosi, Rene, Kong, Ling, Kurmi, Om, Lancaster, Garry, Lewington, Sarah, Lin, Kuang, McDonnell, John, Nie, Qunhua, Radhakrishnan, Jayakrishnan, Ryder, Paul, Sansome, Sam, Schmidt, Dan, Sherliker, Paul, Sohoni, Rajani, Stevens, Becky, Turnbull, Iain, Wang, Jenny, Wang, Lin, Wright, Neil, Yang, Xiaoming, Han, Xiao, Hou, Can, Pei, Pei, Liu, Chao, Tan, Yunlong, Pang, Zengchang, Li, Shanpeng, Wang, Shaojie, Liu, Yongmei, Du, Ranran, Zang, Yajing, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Zhai, Yaoming, Ning, Feng, Sun, Xiaohui, Li, Feifei, Lv, Silu, Wang, Junzheng, Hou, Wei, Zeng, Mingyuan, Jiang, Ge, Zhou, Xue, Yang, Liqiu, He, Hui, Yu, Bo, Li, Yanjie, Xu, Qinai, Kang, Quan, Guo, Ziyan, Wang, Dan, Hu, Ximin, Chen, Jinyan, Fu, Yan, Fu, Zhenwang, Wang, Xiaohuan, Weng, Min, Guo, Zhendong, Wu, Shukuan, Li, Yilei, Li, Huimei, Fu, Zhifang, Wu, Ming, Zhou, Yonglin, Zhou, Jinyi, Tao, Ran, Yang, Jie, Su, Jian, Liu, Fang, Zhang, Jun, Hu, Yihe, Lu, Yan, Ma, Liangcai, Tang, Aiyu, Zhang, Shuo, Jin, Jianrong, Liu, Jingchao, Tang, Zhenzhu, Chen, Naying, Huang, Ying, Li, Mingqiang, Meng, Jinhuai, Pan, Rong, Jiang, Qilian, Lan, Jian, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Wang, Ping, Meng, Fanwen, Qin, Yulu, Wang, Sisi, Wu, Xianping, Zhang, Ningmei, Zhou, Weiwei, Luo, Guojin, Li, Jianguo, Chen, Xiaofang, Zhong, Xunfu, Liu, Jiaqiu, Sun, Qiang, Ge, Pengfei, Ren, Xiaolan, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Zhang, Ding, Zhou, Gang, Feng, Shixian, Chang, Liang, Fan, Lei, Gao, Yulian, He, Tianyou, Sun, Huarong, Hu, Chen, Zhang, Xukui, Wu, Huifang, He, Pan, Yu, Min, Hu, Ruying, Wang, Hao, Qian, Yijian, Wang, Chunmei, Xie, Kaixu, Chen, Lingli, Zhang, Yidan, Pan, Dongxia, Gu, Qijun, Huang, Yuelong, Chen, Biyun, Yin, Li, Liu, Huilin, Fu, Zhongxi, Xu, Qiaohua, Xu, Xin, Zhang, Hao, Long, Huajun, Li, Xianzhi, Zhang, Libo, Qiu, Zhe, Huang, Tao, Afzal, Shoaib, Yu, Canqing, Guo, Yu, Bian, Zheng, Yang, Ling, Millwood, Iona Y., Walters, Robin G., Chen, Yiping, Chen, Ningyu, Gao, Ruqin, Chen, Junshi, Clarke, Robert, Chen, Zhengming, Ellervik, Christina, Nordestgaard, Børge G., Lv, Jun, Li, Liming, Collins, Rory, Peto, Richard, Avery, Daniel, Boxall, Ruth, Bennett, Derrick, Chang, Yumei, Du, Huaidong, Gilbert, Simon, Hacker, Alex, Hill, Mike, Holmes, Michael, Iona, Andri, Kartsonaki, Christiana, Kerosi, Rene, Kong, Ling, Kurmi, Om, Lancaster, Garry, Lewington, Sarah, Lin, Kuang, McDonnell, John, Nie, Qunhua, Radhakrishnan, Jayakrishnan, Ryder, Paul, Sansome, Sam, Schmidt, Dan, Sherliker, Paul, Sohoni, Rajani, Stevens, Becky, Turnbull, Iain, Wang, Jenny, Wang, Lin, Wright, Neil, Yang, Xiaoming, Han, Xiao, Hou, Can, Pei, Pei, Liu, Chao, Tan, Yunlong, Pang, Zengchang, Li, Shanpeng, Wang, Shaojie, Liu, Yongmei, Du, Ranran, Zang, Yajing, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Zhai, Yaoming, Ning, Feng, Sun, Xiaohui, Li, Feifei, Lv, Silu, Wang, Junzheng, Hou, Wei, Zeng, Mingyuan, Jiang, Ge, Zhou, Xue, Yang, Liqiu, He, Hui, Yu, Bo, Li, Yanjie, Xu, Qinai, Kang, Quan, Guo, Ziyan, Wang, Dan, Hu, Ximin, Chen, Jinyan, Fu, Yan, Fu, Zhenwang, Wang, Xiaohuan, Weng, Min, Guo, Zhendong, Wu, Shukuan, Li, Yilei, Li, Huimei, Fu, Zhifang, Wu, Ming, Zhou, Yonglin, Zhou, Jinyi, Tao, Ran, Yang, Jie, Su, Jian, Liu, Fang, Zhang, Jun, Hu, Yihe, Lu, Yan, Ma, Liangcai, Tang, Aiyu, Zhang, Shuo, Jin, Jianrong, Liu, Jingchao, Tang, Zhenzhu, Chen, Naying, Huang, Ying, Li, Mingqiang, Meng, Jinhuai, Pan, Rong, Jiang, Qilian, Lan, Jian, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Wang, Ping, Meng, Fanwen, Qin, Yulu, Wang, Sisi, Wu, Xianping, Zhang, Ningmei, Zhou, Weiwei, Luo, Guojin, Li, Jianguo, Chen, Xiaofang, Zhong, Xunfu, Liu, Jiaqiu, Sun, Qiang, Ge, Pengfei, Ren, Xiaolan, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Zhang, Xi, Zhang, Ding, Zhou, Gang, Feng, Shixian, Chang, Liang, Fan, Lei, Gao, Yulian, He, Tianyou, Sun, Huarong, Hu, Chen, Zhang, Xukui, Wu, Huifang, He, Pan, Yu, Min, Hu, Ruying, Wang, Hao, Qian, Yijian, Wang, Chunmei, Xie, Kaixu, Chen, Lingli, Zhang, Yidan, Pan, Dongxia, Gu, Qijun, Huang, Yuelong, Chen, Biyun, Yin, Li, Liu, Huilin, Fu, Zhongxi, Xu, Qiaohua, Xu, Xin, Zhang, Hao, Long, Huajun, Li, Xianzhi, Zhang, Libo, and Qiu, Zhe
- Abstract
Background: Randomised control trials and genetic analyses have demonstrated that vitamin D or 25-hydroxyvitamin D (25[OH]D) levels may not play a causal role in the development of cardiovascular disease. However, it is unclear if 25(OH)D is causally associated with cause-specific vascular disease and lipids. Therefore, we examined the causal association of 25(OH)D with myocardial infarction, stroke, ischaemic heart disease, ischaemic stroke, subarachnoid haemorrhage, intracerebral haemorrhage, and lipid levels among both Chinese and Europeans. Methods: We used a Mendelian randomisation (MR) design in the China Kadoorie Biobank, the Copenhagen City Heart Study, and the Copenhagen General Population Study. The 25(OH)D-related genetic variants in the CYP2R1 and DCHR7 genes were genotyped in 99,012 Chinese adults and 106,911 Danish adults. Results: In Chinese adults, plasma 25(OH)D levels were not significantly associated with cause-specific vascular disease or mortality, with the exception of intracerebral haemorrhage (HR, 1.09 [95% CI, 1.01,1.18] per 25 nmol/L higher plasma 25(OH)D). In Europeans, plasma 25(OH)D levels were inversely associated with all types of vascular diseases and mortality. However, MR analysis did not demonstrate causal associations of genetically increased 25(OH)D levels with cause-specific vascular diseases, or mortality in both Chinese and European adults. In addition, each 25 nmol/L higher 25(OH)D was observationally associated with lower total cholesterol and low-density lipoprotein cholesterol levels, but higher high-density lipoprotein cholesterol levels. Likewise, MR analysis showed that 25(OH)D levels were not causally associated with lipids in both Chinese and European adults after Bonferroni correction. Conclusions: We found no evidence to support that genetically increased 25(OH)D was associated with a lower risk of ischaemic stroke, intracerebral haemorrhage, subarachnoid haemorrhage, and lipid levels in both Chinese and European
- Published
- 2019
16. Carotid Intima‐Media Thickness but Not Carotid Artery Plaque in Healthy Individuals Is Linked to Lean Body Mass
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Arnold, Matthew, primary, Linden, Andrew, additional, Clarke, Robert, additional, Guo, Yu, additional, Du, Huaidong, additional, Bian, Zheng, additional, Wan, Eric, additional, Yang, Meng, additional, Wang, Liang, additional, Chen, Yuexin, additional, Chen, Jianwei, additional, Long, Huajun, additional, Gu, Qijun, additional, Collins, Rory, additional, Li, Liming, additional, Chen, Zhengming, additional, Parish, Sarah, additional, Chen, Junshi, additional, Lv, Jun, additional, Peto, Richard, additional, Walters, Robin, additional, Bennett, Derrick, additional, Boxall, Ruth, additional, Bragg, Fiona, additional, Chang, Yumei, additional, Chen, Yiping, additional, Gilbert, Simon, additional, Hacker, Alex, additional, Holmes, Michael, additional, Kartsonaki, Christiana, additional, Kerosi, Rene, additional, Lancaster, Garry, additional, Lin, Kuang, additional, McDonnell, John, additional, Millwood, Iona, additional, Nie, Qunhua, additional, Yao, Pang, additional, Ryder, Paul, additional, Sansome, Sam, additional, Schmidt, Dan, additional, Sohoni, Rajani, additional, Turnbull, Iain, additional, Wang, Jenny, additional, Wang, Lin, additional, Wright, Neil, additional, Yang, Ling, additional, Yang, Xiaoming, additional, Han, Xiao, additional, Hou, Can, additional, Jing, Biao, additional, Liu, Chao, additional, Pei, Pei, additional, Tan, Yunlong, additional, Yu, Canqing, additional, Gao, Ruqin, additional, Li, Shanpeng, additional, Wang, Shaojie, additional, Liu, Yongmei, additional, Du, Ranran, additional, Zang, Yajing, additional, Cheng, Liang, additional, Tian, Xiaocao, additional, Zhang, Hua, additional, Zhai, Yaoming, additional, Ning, Feng, additional, Sun, Xiaohui, additional, Li, Feifei, additional, Lv, Silu, additional, Wang, Junzheng, additional, Hou, Wei, additional, Zeng, Mingyuan, additional, Jiang, Ge, additional, Yang, Liqiu, additional, He, Hui, additional, Yu, Bo, additional, Li, Yanjie, additional, Xu, Qinai, additional, Kang, Quan, additional, Wang, Dan, additional, Hu, Ximin, additional, Wang, Hongmei, additional, Chen, Jinyan, additional, Fu, Yan, additional, Fu, Zhenwang, additional, Wang, Xiaohuan, additional, Weng, Min, additional, Guo, Zhendong, additional, Wu, Shukuan, additional, Li, Yilei, additional, Li, Huimei, additional, Fu, Zhifang, additional, Wu, Ming, additional, Zhou, Yonglin, additional, Zhou, Jinyi, additional, Tao, Ran, additional, Yang, Jie, additional, Su, Jian, additional, Liu, Fang, additional, Zhang, Jun, additional, Hu, Yihe, additional, Lu, Yan, additional, Ma, Liangcai, additional, Tang, Aiyu, additional, Zhang, Shuo, additional, Jin, Jianrong, additional, Liu, Jingchao, additional, Tang, Zhenzhu, additional, Chen, Naying, additional, Huang, Ying, additional, Li, Mingqiang, additional, Meng, Jinhuai, additional, Pan, Rong, additional, Jiang, Qilian, additional, Lan, Jian, additional, Liu, Yun, additional, Wei, Liuping, additional, Zhou, Liyuan, additional, Chen, Ningyu, additional, Wang, Ping, additional, Meng, Fanwen, additional, Qin, Yulu, additional, Wang, Sisi, additional, Wu, Xianping, additional, Zhang, Ningmei, additional, Chen, Xiaofang, additional, Zhou, Weiwei, additional, Luo, Guojin, additional, Li, Jianguo, additional, Zhong, Xunfu, additional, Liu, Jiaqiu, additional, Sun, Qiang, additional, Ge, Pengfei, additional, Ren, Xiaolan, additional, Dong, Caixia, additional, Zhang, Hui, additional, Mao, Enke, additional, Wang, Xiaoping, additional, Wang, Tao, additional, Zhang, Xi, additional, Zhang, Ding, additional, Zhou, Gang, additional, Feng, Shixian, additional, Chang, Liang, additional, Fan, Lei, additional, Gao, Yulian, additional, He, Tianyou, additional, Sun, Huarong, additional, He, Pan, additional, Hu, Chen, additional, Zhang, Xukui, additional, Wu, Huifang, additional, Yu, Min, additional, Hu, Ruying, additional, Wang, Hao, additional, Qian, Yijian, additional, Wang, Chunmei, additional, Xie, Kaixu, additional, Chen, Lingli, additional, Zhang, Yidan, additional, Pan, Dongxia, additional, Huang, Yuelong, additional, Chen, Biyun, additional, Yin, Li, additional, Liu, Huilin, additional, Fu, Zhongxi, additional, Xu, Qiaohua, additional, Xu, Xin, additional, Zhang, Hao, additional, Li, Xianzhi, additional, Zhang, Libo, additional, and Qiu, Zhe, additional
- Published
- 2019
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17. Solid Fuel Use and Risks of Respiratory Diseases. A Cohort Study of 280,000 Chinese Never-Smokers
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Chan, Ka Hung, primary, Kurmi, Om P., additional, Bennett, Derrick A., additional, Yang, Ling, additional, Chen, Yiping, additional, Tan, Yunlong, additional, Pei, Pei, additional, Zhong, Xunfu, additional, Chen, Jianxin, additional, Zhang, Jun, additional, Kan, Haidong, additional, Peto, Richard, additional, Lam, Kin Bong Hubert, additional, Chen, Zhengming, additional, Chen, Junshi, additional, Clarke, Robert, additional, Collins, Rory, additional, Guo, Yu, additional, Li, Liming, additional, Lv, Jun, additional, Walters, Robin, additional, Avery, Daniel, additional, Bennett, Derrick, additional, Boxall, Ruth, additional, Chang, Yumei, additional, Du, Huaidong, additional, Gilbert, Simon, additional, Hacker, Alex, additional, Holmes, Michael, additional, Kartsonaki, Christiana, additional, Kerosi, Rene, additional, Lancaster, Garry, additional, Lin, Kuang, additional, McDonnell, John, additional, Millwood, Iona, additional, Nie, Qunhua, additional, Radhakrishnan, Jayakrishnan, additional, Ryder, Paul, additional, Sansome, Sam, additional, Schmidt, Dan, additional, Sohoni, Rajani, additional, Stevens, Becky, additional, Turnbull, Iain, additional, Wang, Jenny, additional, Wang, Lin, additional, Wright, Neil, additional, Yang, Xiaoming, additional, Bian, Zheng, additional, Han, Xiao, additional, Hou, Can, additional, Liu, Chao, additional, Jing, Biao, additional, Yu, Canqing, additional, Pang, Zengchang, additional, Gao, Ruqin, additional, Li, Shanpeng, additional, Wang, Shaojie, additional, Liu, Yongmei, additional, Du, Ranran, additional, Zang, Yajing, additional, Cheng, Liang, additional, Tian, Xiaocao, additional, Zhang, Hua, additional, Zhai, Yaoming, additional, Ning, Feng, additional, Sun, Xiaohui, additional, Li, Feifei, additional, Lv, Silu, additional, Wang, Junzheng, additional, Hou, Wei, additional, Zeng, Mingyuan, additional, Jiang, Ge, additional, Zhou, Xue, additional, Yang, Liqiu, additional, He, Hui, additional, Yu, Bo, additional, Li, Yanjie, additional, Xu, Qinai, additional, Kang, Quan, additional, Guo, Ziyan, additional, Wang, Dan, additional, Hu, Ximin, additional, Wang, Hongmei, additional, Chen, Jinyan, additional, Fu, Yan, additional, Fu, Zhenwang, additional, Wang, Xiaohuan, additional, Weng, Min, additional, Guo, Zhendong, additional, Wu, Shukuan, additional, Li, Yilei, additional, Li, Huimei, additional, Fu, Zhifang, additional, Wu, Ming, additional, Zhou, Yonglin, additional, Zhou, Jinyi, additional, Tao, Ran, additional, Yang, Jie, additional, Su, Jian, additional, Liu, Fang, additional, Hu, Yihe, additional, Lu, Yan, additional, Ma, Liangcai, additional, Tang, Aiyu, additional, Zhang, Shuo, additional, Jin, Jianrong, additional, Liu, Jingchao, additional, Tang, Zhenzhu, additional, Chen, Naying, additional, Huang, Ying, additional, Li, Mingqiang, additional, Meng, Jinhuai, additional, Pan, Rong, additional, Jiang, Qilian, additional, Lan, Jian, additional, Liu, Yun, additional, Wei, Liuping, additional, Zhou, Liyuan, additional, Chen, Ningyu, additional, Wang, Ping, additional, Meng, Fanwen, additional, Qin, Yulu, additional, Wang, Sisi, additional, Wu, Xianping, additional, Zhang, Ningmei, additional, Chen, Xiaofang, additional, Zhou, Weiwei, additional, Luo, Guojin, additional, Li, Jianguo, additional, Liu, Jiaqiu, additional, Sun, Qiang, additional, Ge, Pengfei, additional, Ren, Xiaolan, additional, Dong, Caixia, additional, Zhang, Hui, additional, Mao, Enke, additional, Wang, Xiaoping, additional, Wang, Tao, additional, Zhang, Xi, additional, Zhang, Ding, additional, Zhou, Gang, additional, Feng, Shixian, additional, Chang, Liang, additional, Fan, Lei, additional, Gao, Yulian, additional, He, Tianyou, additional, Sun, Huarong, additional, Hu, Chen, additional, Zhang, Xukui, additional, Wu, Huifang, additional, He, Pan, additional, Yu, Min, additional, Hu, Ruying, additional, Wang, Hao, additional, Qian, Yijian, additional, Wang, Chunmei, additional, Xie, Kaixu, additional, Chen, Lingli, additional, Zhang, Yidan, additional, Pan, Dongxia, additional, Gu, Qijun, additional, Huang, Yuelong, additional, Chen, Biyun, additional, Yin, Li, additional, Liu, Huilin, additional, Fu, Zhongxi, additional, Xu, Qiaohua, additional, Xu, Xin, additional, Zhang, Hao, additional, Long, Huajun, additional, Li, Xianzhi, additional, Zhang, Libo, additional, and Qiu, Zhe, additional
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- 2019
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18. Breastfeeding and the Risk of Maternal Cardiovascular Disease: A Prospective Study of 300 000 Chinese Women
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Peters, Sanne A. E., Yang, Ling, Guo, Yu, Chen, Yiping, Bian, Zheng, Du, Jianwei, Yang, Jie, Li, Shanpeng, Li, Liming, Woodward, Mark, Chen, Zhengming, Chen, Junshi, Collins, Rory, Peto, Richard, Bennett, Derrick, Chang, Yumei, Clarke, Robert, Du, Huaidong, Fan, Xuejuan, Gilbert, Simon, Hacker, Alex, Holmes, Michael, Iona, Andri, Kartsonaki, Christiana, Kerosi, Rene, Kong, Ling, Kurmi, Om, Lancaster, Garry, Lewington, Sarah, McDonnell, John, Millwood, Iona, Nie, Qunhua, Radhakrishnan, Jayakrishnan, Rafiq, Sajjad, Ryder, Paul, Sansome, Sam, Schmidt, Dan, Sherliker, Paul, Sohoni, Rajani, Turnbull, Iain, Walters, Robin, Wang, Jenny, Wang, Lin, Yang, Xiaoming, Chen, Ge, Han, Bingyang, Hou, Can, Lv, Jun, Pei, Pei, Qu, Shuzhen, Tan, Yunlong, Yu, Canqing, Zhou, Huiyan, Pang, Zengchang, Gao, Ruqin, Wang, Shaojie, Liu, Yongmei, Du, Ranran, Zang, Yajing, Cheng, Liang, Tian, Xiaocao, Zhang, Hua, Lv, Silu, Wang, Junzheng, Hou, Wei, Yin, Jiyuan, Jiang, Ge, Liu, Shumei, Pang, Zhigang, Zhou, Xue, Yang, Liqiu, He, Hui, Yu, Bo, Li, Yanjie, Mu, Huaiyi, Xu, Qinai, Dou, Meiling, Ren, Jiaojiao, Wang, Shanqing, Hu, Ximin, Wang, Hongmei, Chen, Jinyan, Fu, Yan, Fu, Zhenwang, Wang, Xiaohuan, Dong, Hua, Weng, Min, Zheng, Xiangyang, Li, Yijun, Li, Huimei, Li, Chenglong, Wu, Ming, Zhou, Jinyi, Tao, Ran, Shen, Jie, Hu, Yihe, Lu, Yan, Gao, Yan, Ma, Liangcai, Zhou, Renxian, Tang, Aiyu, Zhang, Shuo, Jin, Jianrong, Tang, Zhenzhu, Chen, Naying, Huang, Ying, Li, Mingqiang, Meng, Jinhuai, Pan, Rong, Jiang, Qilian, Qing, Jingxin, Zhang, Weiyuan, Liu, Yun, Wei, Liuping, Zhou, Liyuan, Chen, Ningyu, Yang, Jun, Guan, Hairong, Wu, Xianping, Zhang, Ningmei, Chen, Xiaofang, Tang, Xuefeng, Luo, Guojin, Li, Jianguo, Wang, Jian, Liu, Jiaqiu, Sun, Qiang, Ge, Pengfei, Ren, Xiaolan, Dong, Caixia, Zhang, Hui, Mao, Enke, Wang, Xiaoping, Wang, Tao, Liu, Guohua, Zhu, Baoyu, Zhou, Gang, Feng, Shixian, Chang, Liang, Fan, Lei, Gao, Yulian, He, Tianyou, Jiang, Li, Sun, Huarong, He, Pan, Hu, Chen, Lv, Qiannan, Zhang, Xukui, Yu, Min, Hu, Ruying, Fang, Le, Wang, Hao, Qian, Yijian, Wang, Chunmei, Xie, Kaixue, Chen, Lingli, Pan, Yaxing, Pan, Dongxia, Huang, Yuelong, Chen, Biyun, Jin, Donghui, Liu, Huilin, Fu, Zhongxi, Xu, Qiaohua, Xu, Xin, g, Youping, Jia, Weifang, Li, Xianzhi, Zhang, Libo, and Qiu, Zhe
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Adult ,medicine.medical_specialty ,Pediatrics ,China ,Time Factors ,Epidemiology ,breastfeeding ,Breastfeeding ,Lower risk ,Risk Assessment ,03 medical and health sciences ,0302 clinical medicine ,Sex Factors ,cardiovascular disease ,Risk Factors ,medicine ,Humans ,030212 general & internal medicine ,Prospective Studies ,Risk factor ,Prospective cohort study ,Stroke ,Original Research ,Aged ,Proportional Hazards Models ,030219 obstetrics & reproductive medicine ,business.industry ,Proportional hazards model ,Incidence ,Hazard ratio ,Age Factors ,Middle Aged ,Protective Factors ,medicine.disease ,Prognosis ,3. Good health ,Breast Feeding ,risk factor ,Cardiovascular Diseases ,Female ,women ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background Breastfeeding confers substantial benefits to child health and has also been associated with lower risk of maternal cardiovascular diseases ( CVDs ) in later life. However, the evidence on the effects of CVD is still inconsistent, especially in East Asians, in whom the frequency and duration of breastfeeding significantly differ from those in the West. Methods and Results In 2004–2008, the nationwide China Kadoorie Biobank recruited 0.5 million individuals aged 30 to 79 years from 10 diverse regions across China. During 8 years of follow‐up, 16 671 incident cases of coronary heart disease and 23 983 cases of stroke were recorded among 289 573 women without prior CVD at baseline. Cox regression yielded adjusted hazard ratios ( HR s) and 95% CIs for incident CVD by breastfeeding. Overall, ≈99% of women had given birth, among whom 97% reported a history of breastfeeding, with a median duration of 12 months per child. Compared with parous women who had never breastfed, ever breastfeeding was associated with a significantly lower risk of CVD , with adjusted HR s of 0.91 (95% CI, 0.84–0.99) for coronary heart disease and 0.92 (95% CI, 0.85–0.99) for stroke. Women who had breastfed for ≥24 months had an 18% ( HR, 0.82; 0.77–0.87) lower risk of coronary heart disease and a 17% ( HR, 0.83; 0.79–0.87) lower risk of stroke compared with women who had never breastfed. Among women who ever breastfed, each additional 6 months of breastfeeding per child was associated with an adjusted HR of 0.96 (95% CI, 0.94–0.98) for coronary heart disease and 0.97 (95% CI, 0.96–0.98) for stroke. Conclusions Among Chinese women, a history of breastfeeding was associated with an ≈10% lower risk of CVD in later life and the magnitude of the inverse association was stronger among those with a longer duration of breastfeeding.
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- 2017
19. Systemic inflammation is associated with incident stroke and heart disease in East Asians.
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Karim, Mohd A., Kartsonaki, Christiana, Bennett, Derrick A., Millwood, Iona Y., Hill, Michael R., Avery, Daniel, Bian, Zheng, Du, Huaidong, Guo, Yu, Qian, Yijian, Qu, Chan, Turnbull, Iain, Schmidt-Valle, Dan, Wang, Chunmei, Yu, Canqing, Lv, Jun, Chen, Junshi, Clarke, Robert, Li, Liming, and Chen, Zhengming
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INFLAMMATION ,STROKE patients ,HEART diseases ,EAST Asians ,CORONARY disease - Abstract
Systemic inflammation, reflected by increased plasma concentrations of C-reactive protein (CRP) and fibrinogen, is associated with increased risk of coronary heart disease, but its relevance for stroke types remains unclear. Moreover, evidence is limited in non-European populations. We investigated associations of CRP and fibrinogen with risks of incident major coronary events (MCE), ischemic stroke (IS) and intracerebral hemorrhage (ICH) in a cohort of Chinese adults. A nested case-control study within the prospective China Kadoorie Biobank included 1,508 incident MCE cases, 5,418 IS cases, 4,476 ICH cases, and 5,285 common controls, aged 30–79 years. High-sensitivity CRP and low-density lipoprotein cholesterol (LDL-C) were measured in baseline plasma samples from all participants, and fibrinogen in a subset (n = 9,380). Logistic regression yielded adjusted odds ratios (ORs) per SD higher usual levels of log-transformed CRP and fibrinogen. The overall mean (SD) baseline LDL-C was 91.6 mg/dL (24.0) and geometric mean (95% CI) CRP and fibrinogen were 0.90 mg/L (0.87–0.93) and 3.01 g/L (2.98–3.03), respectively. There were approximately log-linear positive associations of CRP with each outcome, which persisted after adjustment for LDL-C and other risk factors, with adjusted ORs (95% CI) per SD higher CRP of 1.67 (1.44–1.94) for MCE and 1.22 (1.10–1.36) for both IS and ICH. No associations of fibrinogen with MCE, IS, or ICH were identified. Adding CRP to prediction models based on established risk factors improved model fit for each of MCE, IS, and ICH, with small improvements in C-statistic and correct reclassification of controls to lower risk groups. Among Chinese adults, who have low mean LDL-C, CRP, but not fibrinogen, was independently associated with increased risks of MCE and stroke. [ABSTRACT FROM AUTHOR]
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- 2020
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20. Age-specific association between blood pressure and vascular and non-vascular chronic diseases in 0·5 million adults in China: a prospective cohort study
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Lacey, Ben, primary, Lewington, Sarah, additional, Clarke, Robert, additional, Kong, Xiang Ling, additional, Chen, Yiping, additional, Guo, Yu, additional, Yang, Ling, additional, Bennett, Derrick, additional, Bragg, Fiona, additional, Bian, Zheng, additional, Wang, Shaojie, additional, Zhang, Hua, additional, Chen, Junshi, additional, Walters, Robin G, additional, Collins, Rory, additional, Peto, Richard, additional, Li, Liming, additional, Chen, Zhengming, additional, Lv, Jun, additional, Walters, Robin, additional, Avery, Daniel, additional, Boxall, Ruth, additional, Chang, Yumei, additional, Du, Huaidong, additional, Gilbert, Simon, additional, Hacker, Alex, additional, Holmes, Michael, additional, Iona, Andri, additional, Kartsonaki, Christiana, additional, Kerosi, Rene, additional, Kurmi, Om, additional, Lancaster, Garry, additional, Lin, Kuang, additional, McDonnell, John, additional, Millwood, Iona, additional, Nie, Qunhua, additional, Radhakrishnan, Jayakrishnan, additional, Ryder, Paul, additional, Sansome, Sam, additional, Schmidt, Dan, additional, Sherliker, Paul, additional, Sohoni, Rajani, additional, Stevens, Becky, additional, Turnbull, Iain, additional, Wang, Jenny, additional, Wang, Lin, additional, Wright, Neil, additional, Yang, Xiaoming, additional, Chen, Ge, additional, Han, Xiao, additional, Hou, Can, additional, Pei, Pei, additional, Qu, Shuzhen, additional, Tan, Yunlong, additional, Yu, Canqing, additional, Pang, Zengchang, additional, Gao, Ruqin, additional, Liu, Yongmei, additional, Du, Ranran, additional, Zang, Yajing, additional, Cheng, Liang, additional, Tian, Xiaocao, additional, Lv, Silu, additional, Wang, Junzheng, additional, Hou, Wei, additional, Yin, Jiyuan, additional, Jiang, Ge, additional, Zhou, Xue, additional, Yang, Liqiu, additional, He, Hui, additional, Yu, Bo, additional, Li, Yanjie, additional, Mu, Huaiyi, additional, Xu, Qinai, additional, Dou, Meiling, additional, Ren, Jiaojiao, additional, Wang, Shanqing, additional, Hu, Ximin, additional, Wang, Hongmei, additional, Chen, Jinyan, additional, Fu, Yan, additional, Fu, Zhenwang, additional, Wang, Xiaohuan, additional, Weng, Min, additional, Zheng, Xiangyang, additional, Li, Yilei, additional, Li, Huimei, additional, Wang, Yanjun, additional, Wu, Ming, additional, Zhou, Jinyi, additional, Tao, Ran, additional, Yang, Jie, additional, Ni, Chuanming, additional, Zhang, Jun, additional, Hu, Yihe, additional, Lu, Yan, additional, Ma, Liangcai, additional, Tang, Aiyu, additional, Zhang, Shuo, additional, Jin, Jianrong, additional, Liu, Jingchao, additional, Tang, Zhenzhu, additional, Chen, Naying, additional, Huang, Ying, additional, Li, Mingqiang, additional, Meng, Jinhuai, additional, Pan, Rong, additional, Jiang, Qilian, additional, Zhang, Weiyuan, additional, Liu, Yun, additional, Wei, Liuping, additional, Zhou, Liyuan, additional, Chen, Ningyu, additional, Guan, Hairong, additional, Wu, Xianping, additional, Zhang, Ningmei, additional, Chen, Xiaofang, additional, Tang, Xuefeng, additional, Luo, Guojin, additional, Li, Jianguo, additional, Zhong, Xunfu, additional, Liu, Jiaqiu, additional, Sun, Qiang, additional, Ge, Pengfei, additional, Ren, Xiaolan, additional, Dong, Caixia, additional, Zhang, Hui, additional, Mao, Enke, additional, Wang, Xiaoping, additional, Wang, Tao, additional, Zhang, Xi, additional, Zhang, Ding, additional, Zhou, Gang, additional, Feng, Shixian, additional, Chang, Liang, additional, Fan, Lei, additional, Gao, Yulian, additional, He, Tianyou, additional, Sun, Huarong, additional, He, Pan, additional, Hu, Chen, additional, Lv, Qiannan, additional, Zhang, Xukui, additional, Yu, Min, additional, Hu, Ruying, additional, Wang, Hao, additional, Qian, Yijian, additional, Wang, Chunmei, additional, Xie, Kaixue, additional, Chen, Lingli, additional, Zhang, Yidan, additional, Pan, Dongxia, additional, Huang, Yuelong, additional, Chen, Biyun, additional, Yin, Li, additional, Jin, Donghui, additional, Liu, Huilin, additional, Fu, Zhongxi, additional, Xu, Qiaohua, additional, Xu, Xin, additional, Zhang, Hao, additional, Xiong, Youping, additional, Long, Huajun, additional, Li, Xianzhi, additional, Zhang, Libo, additional, and Qiu, Zhe, additional
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- 2018
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21. Smoking and smoking cessation in relation to risk of diabetes in Chinese men and women: a 9-year prospective study of 0·5 million people
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Liu, Xin, primary, Bragg, Fiona, additional, Yang, Ling, additional, Kartsonaki, Christiana, additional, Guo, Yu, additional, Du, Huaidong, additional, Bian, Zheng, additional, Chen, Yiping, additional, Yu, Canqing, additional, Lv, Jun, additional, Wang, Kang, additional, Zhang, Hua, additional, Chen, Junshi, additional, Clarke, Robert, additional, Collins, Rory, additional, Peto, Richard, additional, Li, Liming, additional, Chen, Zhengming, additional, Walters, Robin, additional, Avery, Daniel, additional, Bennett, Derrick, additional, Boxall, Ruth, additional, Chang, Yumei, additional, Gilbert, Simon, additional, Hacker, Alex, additional, Holmes, Michael, additional, Kerosi, Rene, additional, Lancaster, Garry, additional, Lin, Kuang, additional, McDonnell, John, additional, Millwood, Iona, additional, Nie, Qunhua, additional, Radhakrishnan, Jayakrishnan, additional, Ryder, Paul, additional, Sansome, Sam, additional, Schmidt, Dan, additional, Sohoni, Rajani, additional, Stevens, Becky, additional, Turnbull, Iain, additional, Wang, Jenny, additional, Wang, Lin, additional, Wright, Neil, additional, Yang, Xiaoming, additional, Chen, Ge, additional, Han, Xiao, additional, Hou, Can, additional, Pei, Pei, additional, Qu, Shuzhen, additional, Tan, Yunlong, additional, Pang, Zengchang, additional, Gao, Ruqin, additional, Wang, Shaojie, additional, Liu, Yongmei, additional, Du, Ranran, additional, Zang, Yajing, additional, Cheng, Liang, additional, Tian, Xiaocao, additional, Lv, Silu, additional, Wang, Junzheng, additional, Hou, Wei, additional, Yin, Jiyuan, additional, Jiang, Ge, additional, Zhou, Xue, additional, Yang, Liqiu, additional, He, Hui, additional, Yu, Bo, additional, Li, Yanjie, additional, Mu, Huaiyi, additional, Xu, Qinai, additional, Dou, Meiling, additional, Ren, Jiaojiao, additional, Wang, Shanqing, additional, Hu, Ximin, additional, Wang, Hongmei, additional, Chen, Jinyan, additional, Fu, Yan, additional, Fu, Zhenwang, additional, Wang, Xiaohuan, additional, Weng, Min, additional, Zheng, Xiangyang, additional, Li, Yilei, additional, Li, Huimei, additional, Wang, Yanjun, additional, Wu, Ming, additional, Zhou, Jinyi, additional, Tao, Ran, additional, Yang, Jie, additional, Ni, Chuanming, additional, Zhang, Jun, additional, Hu, Yihe, additional, Lu, Yan, additional, Ma, Liangcai, additional, Tang, Aiyu, additional, Zhang, Shuo, additional, Jin, Jianrong, additional, Liu, Jingchao, additional, Tang, Zhenzhu, additional, Chen, Naying, additional, Huang, Ying, additional, Li, Mingqiang, additional, Meng, Jinhuai, additional, Pan, Rong, additional, Jiang, Qilian, additional, Zhang, Weiyuan, additional, Liu, Yun, additional, Wei, Liuping, additional, Zhou, Liyuan, additional, Chen, Ningyu, additional, Guan, Hairong, additional, Wu, Xianping, additional, Zhang, Ningmei, additional, Chen, Xiaofang, additional, Tang, Xuefeng, additional, Luo, Guojin, additional, Li, Jianguo, additional, Zhong, Xunfu, additional, Liu, Jiaqiu, additional, Sun, Qiang, additional, Ge, Pengfei, additional, Ren, Xiaolan, additional, Dong, Caixia, additional, Zhang, Hui, additional, Mao, Enke, additional, Wang, Xiaoping, additional, Wang, Tao, additional, Zhang, Xi, additional, Zhang, Ding, additional, Zhou, Gang, additional, Feng, Shixian, additional, Chang, Liang, additional, Fan, Lei, additional, Gao, Yulian, additional, He, Tianyou, additional, Sun, Huarong, additional, He, Pan, additional, Hu, Chen, additional, Lv, Qiannan, additional, Zhang, Xukui, additional, Yu, Min, additional, Hu, Ruying, additional, Wang, Hao, additional, Qian, Yijian, additional, Wang, Chunmei, additional, Xie, Kaixue, additional, Chen, Lingli, additional, Zhang, Yidan, additional, Pan, Dongxia, additional, Huang, Yuelong, additional, Chen, Biyun, additional, Yin, Li, additional, Jin, Donghui, additional, Liu, Huilin, additional, Fu, Zhongxi, additional, Xu, Qiaohua, additional, Xu, Xin, additional, Zhang, Hao, additional, Xiong, Youping, additional, Long, Huajun, additional, Li, Xianzhi, additional, Zhang, Libo, additional, and Qiu, Zhe, additional
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- 2018
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22. Self‐Rated Health Status and Risk of Ischemic Heart Disease in the China Kadoorie Biobank Study: A Population‐Based Cohort Study
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Dong, Wenhong, primary, Pan, Xiong‐Fei, additional, Yu, Canqing, additional, Lv, Jun, additional, Guo, Yu, additional, Bian, Zheng, additional, Yang, Ling, additional, Chen, Yiping, additional, Wu, Tangchun, additional, Chen, Zhengming, additional, Pan, An, additional, Li, Liming, additional, Chen, Junshi, additional, Collins, Rory, additional, Peto, Richard, additional, Avery, Daniel, additional, Boxall, Ruth, additional, Derrick, Bennett, additional, Chang, Yumei, additional, Clarke, Robert, additional, Du, Huaidong, additional, Gilbert, Simon, additional, Hacker, Alex, additional, Hill, Mike, additional, Holmes, Michael, additional, Iona, Andri, additional, Kartsonaki, Christiana, additional, Kerosi, Rene, additional, Kong, Ling, additional, Kurmi, Om, additional, Lancaster, Garry, additional, Lewington, Sarah, additional, Lin, Kuang, additional, McDonnell, John, additional, Millwood, Iona, additional, Nie, Qunhua, additional, Radhakrishnan, Jayakrishnan, additional, Rafiq, Sajjad, additional, Ryder, Paul, additional, Sansome, Sam, additional, Schmidt, Dan, additional, Sherliker, Paul, additional, Sohoni, Rajani, additional, Stevens, Becky, additional, Turnbull, Iain, additional, Walters, Robin, additional, Wang, Jenny, additional, Wang, Lin, additional, Wright, Neil, additional, Yang, Xiaoming, additional, Han, Xiao, additional, Hou, Can, additional, Pei, Pei, additional, Tan, Yunlong, additional, Pang, Zengchang, additional, Gao, Ruqin, additional, Li, Shanpeng, additional, Wang, Shaojie, additional, Liu, Yongmei, additional, Du, Ranran, additional, Zang, Yajing, additional, Cheng, Liang, additional, Tian, Xiaocao, additional, Zhang, Hua, additional, Zhai, Yaoming, additional, Ning, Feng, additional, Sun, Xiaohui, additional, Li, Feifei, additional, Lv, Silu, additional, Wang, Junzheng, additional, Hou, Wei, additional, Zeng, Mingyuan, additional, Jiang, Ge, additional, Zhou, Xue, additional, Yang, Liqiu, additional, He, Hui, additional, Yu, Bo, additional, Li, Yanjie, additional, Xu, Qinai, additional, Kang, Quan, additional, Guo, Ziyan, additional, Wang, Dan, additional, Hu, Ximin, additional, Wang, Hongmei, additional, Chen, Jinyan, additional, Fu, Yan, additional, Fu, Zhenwang, additional, Wang, Xiaohuan, additional, Weng, Min, additional, Guo, Zhendong, additional, Wu, Shukuan, additional, Li, Yilei, additional, Li, Huimei, additional, Fu, Zhifang, additional, Wu, Ming, additional, Zhou, Yonglin, additional, Zhou, Jinyi, additional, Tao, Ran, additional, Yang, Jie, additional, Su, Jian, additional, liu, Fang, additional, Zhang, Jun, additional, Hu, Yihe, additional, Lu, Yan, additional, Ma, Liangcai, additional, Tang, Aiyu, additional, Zhang, Shuo, additional, Jin, Jianrong, additional, Liu, Jingchao, additional, Tang, Zhenzhu, additional, Chen, Naying, additional, Huang, Ying, additional, Li, Mingqiang, additional, Meng, Jinhuai, additional, Pan, Rong, additional, Jiang, Qilian, additional, Lan, Jian, additional, Liu, Yun, additional, Wei, Liuping, additional, Zhou, Liyuan, additional, Chen, Ningyu, additional, Wang, Ping, additional, Meng, Fanwen, additional, Qin, Yulu, additional, Wang, Sisi, additional, Wu, Xianping, additional, Zhang, Ningmei, additional, Chen, Xiaofang, additional, Zhou, Weiwei, additional, Luo, Guojin, additional, Li, Jianguo, additional, Zhong, Xunfu, additional, Liu, Jiaqiu, additional, Sun, Qiang, additional, Ge, Pengfei, additional, Ren, Xiaolan, additional, Dong, Caixia, additional, Zhang, Hui, additional, Mao, Enke, additional, Wang, Xiaoping, additional, Wang, Tao, additional, zhang, Xi, additional, Zhang, Ding, additional, Zhou, Gang, additional, Feng, Shixian, additional, Chang, Liang, additional, Fan, Lei, additional, Gao, Yulian, additional, He, Tianyou, additional, Sun, Huarong, additional, He, Pan, additional, Hu, Chen, additional, Zhang, Xukui, additional, Wu, Huifang, additional, Yu, Min, additional, Hu, Ruying, additional, Wang, Hao, additional, Qian, Yijian, additional, Wang, Chunmei, additional, Xie, Kaixu, additional, Chen, Lingli, additional, Zhang, Yidan, additional, Pan, Dongxia, additional, Gu, Qijun, additional, Huang, Yuelong, additional, Chen, Biyun, additional, Yin, Li, additional, Liu, Huilin, additional, Fu, Zhongxi, additional, Xu, Qiaohua, additional, Xu, Xin, additional, Zhang, Hao, additional, Long, Huajun, additional, Li, Xianzhi, additional, Zhang, Libo, additional, and Qiu, Zhe, additional
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- 2017
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23. Adherence to Healthy Lifestyle and Cardiovascular Diseases in the Chinese Population
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Lv, Jun, primary, Yu, Canqing, additional, Guo, Yu, additional, Bian, Zheng, additional, Yang, Ling, additional, Chen, Yiping, additional, Tang, Xuefeng, additional, Zhang, Weiyuan, additional, Qian, Yijian, additional, Huang, Yuelong, additional, Wang, Xiaoping, additional, Chen, Junshi, additional, Chen, Zhengming, additional, Qi, Lu, additional, Li, Liming, additional, Collins, Rory, additional, Peto, Richard, additional, Avery, Daniel, additional, Boxall, Ruth, additional, Bennett, Derrick, additional, Chang, Yumei, additional, Clarke, Robert, additional, Du, Huaidong, additional, Gilbert, Simon, additional, Hacker, Alex, additional, Holmes, Michael, additional, Iona, Andri, additional, Kartsonaki, Christiana, additional, Kerosi, Rene, additional, Kong, Ling, additional, Kurmi, Om, additional, Lancaster, Garry, additional, Lewington, Sarah, additional, Lin, Kuang, additional, McDonnell, John, additional, Mei, Winnie, additional, Millwood, Iona, additional, Nie, Qunhua, additional, Radhakrishnan, Jayakrishnan, additional, Rafiq, Sajjad, additional, Ryder, Paul, additional, Sansome, Sam, additional, Schmidt, Dan, additional, Sherliker, Paul, additional, Sohoni, Rajani, additional, Turnbull, Iain, additional, Walters, Robin, additional, Wang, Jenny, additional, Wang, Lin, additional, Yang, Xiaoming, additional, Chen, Ge, additional, Han, Bingyang, additional, Hou, Can, additional, Lv, Jun, additional, Pei, Pei, additional, Qu, Shuzhen, additional, Tan, Yunlong, additional, Yu, Caning, additional, Zhou, Haiyan, additional, Pang, Zeng hang, additional, Gao, Ruin, additional, Wang, Shoji, additional, Liu, Yong-Mei, additional, Du, Ran ran, additional, Zang, Yajing, additional, Cheng, Liang, additional, Tian, Xiaocao, additional, Zhang, Hua, additional, Lv, Silu, additional, Wang, Junzheng, additional, Hou, Wei, additional, Yin, Jiyuan, additional, Jiang, Ge, additional, Zhou, Xue, additional, Yang, Liqiu, additional, He, Hui, additional, Yu, Bo, additional, Li, Yanjie, additional, Mu, Huaiyi, additional, Xu, Qinai, additional, Dou, Meiling, additional, Ren, Jiaojiao, additional, Wang, Shanqing, additional, Hu, Ximin, additional, Wang, Hongmei, additional, Chen, Jinyan, additional, Fu, Yan, additional, Fu, Zhenwang, additional, Wang, Xiaohuan, additional, Weng, Min, additional, Zheng, Xiangyang, additional, Li, Yilei, additional, Li, Huimei, additional, Wang, Yanjun, additional, Wu, Ming, additional, Zhou, Jinyi, additional, Tao, Ran, additional, Yang, Jie, additional, Ni, Chuanming, additional, Zhang, Jun, additional, Hu, Yihe, additional, Lu, Yan, additional, Ma, Liangcai, additional, Tang, Aiyu, additional, Zhang, Shuo, additional, Jin, Jianrong, additional, Liu, Jingchao, additional, Tang, Zhenzhu, additional, Chen, Naying, additional, Huang, Ying, additional, Li, Mingqiang, additional, Meng, Jinhuai, additional, Pan, Rong, additional, Jiang, Qilian, additional, Liu, Yun, additional, Wei, Liuping, additional, Zhou, Liyuan, additional, Chen, Ningyu, additional, Guan, Hairong, additional, Wu, Xianping, additional, Zhang, Ningmei, additional, Chen, Xiaofang, additional, Luo, Guojin, additional, Li, Jianguo, additional, Zhong, Xunfu, additional, Liu, Jiaqiu, additional, Sun, Qiang, additional, Ge, Pengfei, additional, Ren, Xiaolan, additional, Dong, Caixia, additional, Zhang, Hui, additional, Mao, Enke, additional, Wang, Tao, additional, zhang, Xi, additional, Zhang, Ding, additional, Zhou, Gang, additional, Feng, Shixian, additional, Chang, Liang, additional, Fan, Lei, additional, Gao, Yulian, additional, He, Tianyou, additional, Sun, Huarong, additional, He, Pan, additional, Hu, Chen, additional, Lv, Qiannan, additional, Zhang, Xukui, additional, Yu, Min, additional, Hu, Ruying, additional, Wang, Hao, additional, Wang, Chunmei, additional, Xie, Kaixue, additional, Chen, Lingli, additional, Zhang, Yidan, additional, Pan, Dongxia, additional, Chen, Biyun, additional, Yin, Li, additional, Jin, Donghui, additional, Liu, Huilin, additional, Fu, Zhongxi, additional, Xu, Qiaohua, additional, Xu, Xin, additional, Zhang, Hao, additional, Xiong, Youping, additional, Long, Huajun, additional, Li, Xianzhi, additional, Zhang, Libo, additional, and Qiu, Zhe, additional
- Published
- 2017
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24. Association of Major Depression With Risk of Ischemic Heart Disease in a Mega‐Cohort of Chinese Adults: The China Kadoorie Biobank Study
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Liu, Na, primary, Pan, Xiong‐Fei, additional, Yu, Canqing, additional, Lv, Jun, additional, Guo, Yu, additional, Bian, Zheng, additional, Yang, Ling, additional, Chen, Yiping, additional, Wu, Tangchun, additional, Chen, Zhengming, additional, Pan, An, additional, Li, Liming, additional, Chen, Junshi, additional, Collins, Rory, additional, Peto, Richard, additional, Lancaster, Garry, additional, Yang, Xiaoming, additional, Williams, Alex, additional, Smith, Margaret, additional, Chang, Yumei, additional, Zhao, Guoqing, additional, Wu, Lixue, additional, Hou, Can, additional, Pang, Zengchang, additional, Wang, Shaojie, additional, Zhang, Yun, additional, Zhang, Kui, additional, Liu, Silu, additional, Zhao, Zhonghou, additional, Liu, Shumei, additional, Pang, Zhigang, additional, Feng, Weijia, additional, Wu, Shuling, additional, Yang, Liqiu, additional, Han, Huili, additional, He, Hui, additional, Pan, Xianhai, additional, Wang, Shanqing, additional, Wang, Hongmei, additional, Hao, Xinhua, additional, Chen, Chunxing, additional, Lin, Shuxiong, additional, Hu, Xiaoshu, additional, Zhou, Minghao, additional, Wu, Ming, additional, Wang, Yeyuan, additional, Hu, Yihe, additional, Ma, Liangcai, additional, Zhou, Renxian, additional, Xu, Guanqun, additional, Dong, Baiqing, additional, Chen, Naying, additional, Huang, Ying, additional, Li, Mingqiang, additional, Meng, Jinhuai, additional, Gan, Zhigao, additional, Xu, Jiujiu, additional, Liu, Yun, additional, Wu, Xianping, additional, Gao, Yali, additional, Zhang, Ningmei, additional, Luo, Guojin, additional, Que, Xiangsan, additional, Chen, Xiaofang, additional, Ge, Pengfei, additional, He, Jian, additional, Ren, Xiaolan, additional, Zhang, Hui, additional, Mao, Enke, additional, Li, Guanzhong, additional, Li, Zhongxiao, additional, He, Jun, additional, Liu, Guohua, additional, Zhu, Baoyu, additional, Zhou, Gang, additional, Feng, Shixian, additional, Gao, Yulian, additional, He, Tianyou, additional, Jiang, Li, additional, Qin, Jianhua, additional, Sun, Huarong, additional, Liu, Liqun, additional, Yu, Min, additional, Chen, Yaping, additional, Hu, Zhixiang, additional, Hu, Jianjin, additional, Qian, Yijian, additional, Wu, Zhiying, additional, Chen, Lingli, additional, Liu, Wen, additional, Li, Guangchun, additional, Liu, Huilin, additional, Long, Xiangquan, additional, Xiong, Youping, additional, Tan, Zhongwen, additional, Xie, Xuqiu, additional, and Peng, Yunfang, additional
- Published
- 2016
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25. Abstract 12708: Adherence to Healthy Lifestyle and Cardiovascular Diseases in Chinese
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Qi, Lu, primary, Lv, Jun, additional, Yu, Canqing, additional, Guo, Yu, additional, Bian, Zheng, additional, Yang, Ling, additional, Chen, Yiping, additional, Tang, Xuefeng, additional, Zhang, Weiyuan, additional, Qian, Yijian, additional, Huang, Yuelong, additional, Wang, Xiaoping, additional, Chen, Junshi, additional, Chen, Zhengming, additional, and Li, Liming, additional
- Published
- 2016
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26. The Genetic Architecture of Depression in Individuals of East Asian Ancestry
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Giannakopoulou, Olga, Lin, Kuang, Meng, Xiangrui, Su, Mei-Hsin, Kuo, Po-Hsiu, Peterson, Roseann E., Awasthi, Swapnil, Moscati, Arden, Coleman, Jonathan R. I., Bass, Nick, Millwood, Iona Y., Chen, Yiping, Chen, Zhengming, Chen, Hsi-Chung, Lu, Mong-Liang, Huang, Ming-Chyi, Chen, Chun-Hsin, Stahl, Eli A., Loos, Ruth J. F., Mullins, Niamh, Ursano, Robert J., Kessler, Ronald C., Stein, Murray B., Sen, Srijan, Scott, Laura J., Burmeister, Margit, Fang, Yu, Tyrrell, Jess, Jiang, Yunxuan, Tian, Chao, McIntosh, Andrew M., Ripke, Stephan, Dunn, Erin C., Kendler, Kenneth S., Walters, Robin G., Lewis, Cathryn M., Kuchenbaecker, Karoline, Wray, Naomi R., Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F. M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T. F., Bigdeli, Tim B., Binder, Elisabeth B., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Colodro-Conde, Lucía, Coon, Hilary, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E., Davies, Gail, Deary, Ian J., Degenhardt, Franziska, Derks, Eske M., Direk, Nese, Dolan, Conor V., Eley, Thalia C., Escott-Price, Valentina, Kiadeh, Farnush Farhadi Hassan, Finucane, Hilary K., Foo, Jerome C., Forstner, Andreas J., Frank, Josef, Gaspar, Héléna A., Gill, Michael, Goes, Fernando S., Gordon, Scott D., Grove, Jakob, Hall, Lynsey S., Hansen, Christine Søholm, Hansen, Thomas F., Herms, Stefan, Hickie, Ian B., Hoffmann, Per, Homuth, Georg, Horn, Carsten, Hottenga, Jouke-Jan, Howard, David M., Hougaard, David M., Ising, Marcus, Jansen, Rick, Jones, Ian, Jones, Lisa A., Jorgenson, Eric, Knowles, James A., Kohane, Isaac S., Kraft, Julia, Kretzschmar, Warren W., Kutalik, Zoltán, Li, Yihan, Lind, Penelope A., Luykx, Jurjen J., MacIntyre, Donald J., MacKinnon, Dean F., Maier, Robert M., Maier, Wolfgang, Marchini, Jonathan, Mbarek, Hamdi, McGrath, Patrick, McGuffin, Peter, Medland, Sarah E., Mehta, Divya, Middeldorp, Christel M., Mihailov, Evelin, Milaneschi, Yuri, Milani, Lili, Mondimore, Francis M., Montgomery, Grant W., Mostafavi, Sara, Nauck, Matthias, Ng, Bernard, Nivard, Michel G., Nyholt, Dale R., O'Reilly, Paul F., Oskarsson, Hogni, Owen, Michael J., Painter, Jodie N., Pedersen, Carsten Bøcker, Pedersen, Marianne Giørtz, Pettersson, Erik, Peyrot, Wouter J., Pistis, Giorgio, Posthuma, Danielle, Quiroz, Jorge A., Qvist, Per, Rice, John P., Riley, Brien P., Rivera, Margarita, Mirza, Saira Saeed, Schoevers, Robert, Schulte, Eva C., Shen, Ling, Shi, Jianxin, Shyn, Stanley I., Sigurdsson, Engilbert, Sinnamon, Grant C. B., Smit, Johannes H., Smith, Daniel J., Stefansson, Hreinn, Steinberg, Stacy, Streit, Fabian, Strohmaier, Jana, Tansey, Katherine E., Teismann, Henning, Teumer, Alexander, Thompson, Wesley, Thompson, Pippa A., Thorgeirsson, Thorgeir E., Traylor, Matthew, Treutlein, Jens, Trubetskoy, Vassily, Uitterlinden, André G., Umbricht, Daniel, Van der Auwera, Sandra, van Hemert, Albert M., Viktorin, Alexander, Visscher, Peter M., Wang, Yunpeng, Webb, Bradley T., Weinsheimer, Shantel Marie, Wellmann, Jürgen, Willemsen, Gonneke, Witt, Stephanie H., Wu, Yang, Xi, Hualin S., Yang, Jian, Zhang, Futao, Arolt, Volker, Baune, Bernhard T, Berger, Klaus, Boomsma, Dorret I., Cichon, Sven, Dannlowski, Udo, de Geus, EJC, DePaulo, J. Raymond, Domenici, Enrico, Domschke, Katharina, Esko, Tõnu, Grabe, Hans J., Hamilton, Steven P., Hayward, Caroline, Heath, Andrew C., Kloiber, Stefan, Lewis, Glyn, Li, Qingqin S., Lucae, Susanne, Madden, Pamela AF, Magnusson, Patrik K., Martin, Nicholas G., Metspalu, Andres, Mors, Ole, Mortensen, Preben Bo, Müller-Myhsok, Bertram, Nordentoft, Merete, Nöthen, Markus M., O'Donovan, Michael C., Paciga, Sara A., Pedersen, Nancy L., Penninx, Brenda WJH, Perlis, Roy H., Porteous, David J., Potash, James B., Preisig, Martin, Rietschel, Marcella, Schaefer, Catherine, Schulze, Thomas G., Smoller, Jordan W., Stefansson, Kari, Tiemeier, Henning, Uher, Rudolf, Völzke, Henry, Weissman, Myrna M., Werge, Thomas, Levinson, Douglas F., Breen, Gerome, Børglum, Anders D., Sullivan, Patrick F., Agee, Michelle, Aslibekyan, Stella, Auton, Adam, Babalola, Elizabeth, Bell, Robert K., Bielenberg, Jessica, Bryc, Katarzyna, Bullis, Emily, Cameron, Briana, Coker, Daniella, Cuellar Partida, Gabriel, Dhamija, Devika, Das, Sayantan, Elson, Sarah L., Filshtein, Teresa, Fletez-Brant, Kipper, Fontanillas, Pierre, Freyman, Will, Gandhi, Pooja M., Heilbron, Karl, Hicks, Barry, Hinds, David A., Huber, Karen E., Jewett, Ethan M., Kleinman, Aaron, Kukar, Katelyn, Lane, Vanessa, Lin, Keng-Han, Lowe, Maya, Luff, Marie K., McCreight, Jennifer C., McIntyre, Matthew H., McManus, Kimberly F., Micheletti, Steven J., Moreno, Meghan E., Mountain, Joanna L., Mozaffari, Sahar V., Nandakumar, Priyanka, Noblin, Elizabeth S., O'Connell, Jared, Petrakovitz, Aaron A., Poznik, G. David, Schumacher, Morgan, Shastri, Anjali J., Shelton, Janie F., Shi, Jingchunzi, Shringarpure, Suyash, Tran, Vinh, Tung, Joyce Y., Wang, Xin, Wang, Wei, Weldon, Catherine H., Wilton, Peter, Avery, Daniel, Bennett, Derrick, Bian, Zheng, Boxall, Ruth, Bragg, Fiona, Chan, Ka Hung, Chang, Liang, Chang, Yumei, Chen, Biyun, Chen, Jinyan, Chen, Junshi, Chen, Naying, Chen, Ningyu, Chen, Xiaofang, Cheng, Liang, Clarke, Johnathan, Clarke, Robert, Collins, Rory, Dong, Caixia, Du, Huaidong, Du, Ranran, Fairhurst-Hunter, Zammy, Fan, Lei, Feng, Shixian, Fu, Zhongxi, Gan, Wei, Gao, Ruqin, Gao, Yulian, Ge, Pengfei, Gilbert, Simon, Gong, Weiwei, Gu, Qijun, Guo, Yu, Guo, Zhendong, Guo, Ziyan, Hacker, Alex, Han, Xiao, Hariri, Parisa, He, Pan, He, Tianyou, Hill, Mike, Holmes, Michael, Hou, Can, Hou, Wei, Hu, Chen, Hu, Ruying, Hu, Ximin, Hu, Yihe, Hua, Hua, Hua, Yujie, Huang, Yuelong, Im, Pek Kei, Iona, Andri, Jiang, Qilian, Jin, Jianrong, Kakkoura, Maria, Kang, Quan, Kartsonaki, Christiana, Kerosi, Rene, Kong, Ling, Lan, Jian, Lancaster, Garry, Li, Feifei, Li, Huimei, Li, Jianguo, Li, Liming, Li, Mingqiang, LI, Shanpeng, Li, Yanjie, Li, Yilei, Li, Zhongxiao, Lingli, Lingli, Liu, Chao, Liu, Depei, Liu, Duo, Liu, Fang, Liu, Huilin, Liu, Jiaqiu, Liu, Jingchao, Liu, Yongmei, Liu, Yun, Long, Huajun, Lu, Yan, Luo, Guojin, Lv, Jun, Lv, Silu, Ma, Liangcai, Mao, Enke, McDonnell, John, Meng, Fanwen, Meng, Jinhuai, Millwood, Iona, Nie, Qunhua, Ning, Feng, Pan, Dongxia, Pan, Rong, Pang, Zengchang, Pei, Pei, Peto, Richard, Pozarickij, Alfred, Qian, Yijian, Qin, Yulu, Qu, Chan, Ren, Xiaolan, Ryder, Paul, Sansome, Sam, Schmidt, Dan, Sherliker, Paul, Sohoni, Rajani, Stevens, Becky, Su, Jian, Sun, Huarong, Sun, Qiang, Sun, Xiaohui, Tang, Aiyu, Tang, Zhenzhu, Tao, Ran, Tian, Xiaocao, Turnbull, Iain, Walters, Robin, Wan, Meng, Wang, Chunmei, Wang, Chen, Wang, Hao, Wang, Junzheng, Wang, Lin, Wang, Ping, Wang, Tao, Wang, Shaojie, Wang, Sisi, Wang, Xiaohuan, Wei, Liuping, Weng, Min, Wright, Neil, Wu, Ming, Wu, Xianping, Wu, Shukuan, Xie, Kaixu, Xu, Qiaohua, Xu, Qinai, Xu, Xin, Yan, Shichun, Yang, Ling, Yang, Xiaoming, Yang, Jie, Yao, Pang, Yin, Li, Yu, Bo, Yu, Canqing, Yu, Min, Zhai, Yaoming, Zhang, Hao, Zhang, Hui, Zhang, Jun, Zhang, Libo, Zhang, Ningmei, Zhang, Xi, Zhang, Xiaoyi, Zhang, Xukui, Zhong, Xunfu, Zhou, Ding Zhang, Zhou, Gang, Zhou, Jinyi, Zhou, Liyuan, Zhou, Weiwei, Zhou, Xue, Zhou, Yonglin, and Zou, Mingyuan
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27. Publisher Correction: Systemic inflammation is associated with incident stroke and heart disease in East Asians.
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Karim MA, Kartsonaki C, Bennett DA, Millwood IY, Hill MR, Avery D, Bian Z, Du H, Guo Y, Qian Y, Qu C, Turnbull I, Schmidt-Valle D, Wang C, Yu C, Lv J, Chen J, Clarke R, Li L, Chen Z, Holmes MV, and Walters RG
- Abstract
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
- Published
- 2020
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28. [Association between sleep duration and stroke in adults].
- Author
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Wu H, Wang H, Hu R, Zhong J, Qian Y, Wang C, Xie K, Chen L, Gong W, Guo Y, Yu M, Chen Z, and Li L
- Subjects
- Adult, Aged, China epidemiology, Female, Humans, Male, Middle Aged, Odds Ratio, Prevalence, Risk Factors, Snoring, Time Factors, Sleep, Stroke epidemiology
- Abstract
Objective: To explore the association between sleep duration and stroke in adults., Methods: Baseline data of 57 704 subjects who were aged 30-79 years and enrolled into China Kadoorie Biobank (CKB) study from Tongxiang county, Zhejiang province were analyzed. Multiple logistic regression analysis was conducted to investigate the putative association between sleep duration and stroke after adjusting for potential confounders., Results: The mean age of the subjects was (53.15 ± 10.20) years in males and (51.72 ± .69) years in females, respectively. There were 14.43% of males and 15.30% of females reporting sleep durations ≤ 6 hours per day and 5.39% of males and 5.95% of females reporting long duration of sleep (≥ 10 hours per day). The prevalence of stroke was 0.92% in males compared with 0.44% in females. The prevalence of stroke showed a U-shaped distribution with sleep duration. Compared with 7 hours sleep duration per day, long sleep duration (≥ 10 hours per day) was associated with stroke. The odds ratios (OR) were 2.11 (95%CI: 1.32-3.37) for males and 2.13 (95%CI: 1.24-3.65) for females after adjusting for age, socioeconomic status, health behaviors and health status. No statistical significant association was found between short sleep duration and stroke. Meanwhile, frequent sleep snoring was found to be associated with stroke in females (OR=1.63, 95% CI: 1.11-2.40)., Conclusion: Longer sleep duration was found to be associated with higher risk of stroke in both males and females. Frequent sleep snoring would increase the risk of stroke in females.
- Published
- 2015
29. Blood pressure in relation to general and central adiposity among 500 000 adult Chinese men and women.
- Author
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Chen Z, Smith M, Du H, Guo Y, Clarke R, Bian Z, Collins R, Chen J, Qian Y, Wang X, Chen X, Tian X, Wang X, Peto R, and Li L
- Subjects
- Adult, Aged, Asian People, Blood Pressure Determination, China, Cross-Sectional Studies, Female, Humans, Linear Models, Male, Middle Aged, Risk Factors, Adiposity physiology, Blood Pressure physiology, Body Mass Index, Waist Circumference, Waist-Hip Ratio
- Abstract
Background: Greater adiposity is associated with higher blood pressure. Substantial uncertainty remains, however, about which measures of adiposity most strongly predict blood pressure and whether these associations differ materially between populations., Methods: We examined cross-sectional data on 500 000 adults recruited from 10 diverse localities across China during 2004-08. Multiple linear regression was used to estimate the effects on systolic blood pressure (SBP) of general adiposity [e.g. body mass index (BMI), body fat percentage, height-adjusted weight] vs central adiposity [e.g. waist circumference (WC), hip circumference (HC), waist-hip ratio (WHR)], before and after adjustment for each other. The main analyses excluded those reported taking any antihypertensive medication, and were adjusted for age, region and education., Results: The overall mean [standard deviation (SD)] BMI was 23.6 (3.3) kg/m(2) and mean WC was 80.0 (9.5) cm. The differences in SBP (men/women, mmHg) per 1SD higher general adiposity (height-adjusted weight: 6.6/5.6; BMI: 5.5/4.9; body fat percentage: 5.5/5.0) were greater than for central adiposity (WC: 5.0/4.3; HC: 4.8/4.1; WHR: 3.7/3.2), with a 10 kg/m(2) greater BMI being associated on average with 16 (men/women: 17/14) mmHg higher SBP. The associations of blood pressure with measures of general adiposity were not materially altered by adjusting for WC and HC, but those for central adiposity were significantly attenuated after adjusting for BMI (WC: 1.1/0.7; HC: 0.3/-0.2; WHR: 0.6/0.6)., Conclusion: In adult Chinese, blood pressure is more strongly associated with general adiposity than with central adiposity, and the associations with BMI were about 50% stronger than those observed in Western populations., (© The Author 2015. Published by Oxford University Press on behalf of the International Epidemiological Association.)
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- 2015
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30. Regional variations in the prevalence and misdiagnosis of air flow obstruction in China: baseline results from a prospective cohort of the China Kadoorie Biobank (CKB).
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Kurmi OP, Li L, Smith M, Augustyn M, Chen J, Collins R, Guo Y, Han Y, Qin J, Xu G, Wang J, Bian Z, Zhou G, Davis K, Peto R, Chen Z, Li L, Chen Z, Chen J, Collins R, Peto R, Chen Z, Lancaster G, Yang X, Williams A, Smith M, Yang L, Chang Y, Millwood I, Chen Y, Lewington S, Sansome S, Walters R, Kurmi O, Guo Y, Bian Z, Hou C, Tan Y, Wang Z, Cai X, Zhou H, Chen X, Pang Z, Li S, Wang S, Lv S, Zhao Z, Liu S, Pang Z, Yang L, He H, Yu B, Wang S, Wang H, Chen C, Zheng X, Hu X, Zhou M, Wu M, Tao R, Wang Y, Hu Y, Ma L, Zhou R, Tang Z, Chen N, Huang Y, Li M, Gan Z, Meng J, Qin J, Wu X, Zhang N, Luo G, Que X, Chen X, Ge P, Ren X, Dong C, Zhang H, Mao E, Li Z, Zhou G, Feng S, Gao Y, He T, Jiang L, Sun H, Yu M, Su D, Lu F, Qian Y, Shi K, Han Y, Chen L, Li G, Liu H, Yin L, Xiong Y, Tan Z, and Jia W
- Abstract
Background: Despite the great burden of chronic respiratory diseases in China, few large multicentre, spirometry-based studies have examined its prevalence, rate of underdiagnosis regionally or the relevance of socioeconomic and lifestyle factors., Methods: We analysed data from 512 891 adults in the China Kadoorie Biobank, recruited from 10 diverse regions of China during 2004-2008. Air flow obstruction (AFO) was defined by the lower limit of normal criteria based on spirometry-measured lung function. The prevalence of AFO was analysed by region, age, socioeconomic status, body mass index (BMI) and smoking history and compared with the prevalence of self-reported physician-diagnosed chronic bronchitis or emphysema (CB/E) and its symptoms., Findings: The prevalence of AFO was 7.3% in men (range 2.5-18.2%) and 6.4% in women (1.5-18.5%). Higher prevalence of AFO was associated with older age (p<0.0001), lower income (p<0.0001), poor education (p<0.001), living in rural regions (p<0.001), those who started smoking before the age of 20 years (p<0.001) and low BMI (p<0.001). Compared with self-reported diagnosis of CB/E, 88.8% of AFO was underdiagnosed; underdiagnosis proportion was highest in 30-39-year olds (96.7%) compared with the 70+ age group (81.1%), in women (90.7%), in urban areas (89.4%), in people earning 5K-10 K ¥ monthly (90.3%) and in those with middle or high school education (92.6%)., Interpretation: In China, the burden of AFO based on spirometry was high and significantly greater than that estimated based on self-reported physician-diagnosed CB/E, especially in rural areas, reflecting major issues with diagnosis of AFO that will impact disease treatment and management.
- Published
- 2014
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31. Evaluation of (99m)Tc-MIBI myocardial perfusion imaging with intravenous infusion of adenosine triphosphate in diagnosis of coronary artery disease.
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He Q, Yao Z, Yu X, Qu W, Sun F, Ji F, Xu F, and Qian Y
- Subjects
- Adult, Aged, Aged, 80 and over, Coronary Angiography, Female, Humans, Male, Middle Aged, Sensitivity and Specificity, Adenosine Triphosphate adverse effects, Coronary Disease diagnosis, Heart diagnostic imaging, Technetium Tc 99m Sestamibi, Tomography, Emission-Computed, Single-Photon
- Abstract
Objective: To evaluate the feasibility, safety and diagnostic accuracy of pharmacologic stress of (99m)Technetium-MIBI single-photon emission computed tomography (SPECT) with intravenous adenosine triphosphate (ATP) in patients with suspected coronary artery disease., Methods: The study group included 263 patients who were suspected of having coronary artery disease. All patients underwent (99m)Tc-MIBI myocardial perfusion imaging with ATP infusion (0.16 mg/kg body weight per min for 5 min). 20 mCi of (99m)Tc-MIBI were injected 3 minutes after the start of ATP infusion. Myocardial SPECT images were obtained 60 minutes later. Then, two days later, 20 mCi of (99m)Tc-MIBI were administered at rest and myocardial SPECT was repeated. 51 patients also underwent coronary angiography within two weeks for evaluation of sensitivity and specificity of ATP-myocardial perfusion imaging in detection of coronary artery disease. The occurrence of cardiac and non-cardiac adverse effects was carefully monitored during and after intravenous ATP infusion., Results: The ATP infusion protocol was completed in all patients. Although 59% of the patients had various kinds of adverse effects, most of them were mild. No patient required aminophyline. The most severe adverse effect was second degree type II atria-ventricular block (4/263), but all events were transient. The sensitivity and specificity of ATP-myocardial perfusion imaging were 97% and 82%, respectively., Conclusions: It is shown that (99m)Technetium-MIBI SPECT with intravenous ATP is a safe and feasible technique for detecting coronary artery disease in patients unable to perform the exercise test.
- Published
- 2002
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