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13 results on '"Qian, Xiaoju"'

4. The yak genome and adaptation to life at high altitude

Author

Qiu, Qiang, Zhang, Guojie, Ma, Tao, Qian, Wubin, Ye, Zhiqiang, Cao, Changchang, Hu, Quanjun, Kim, Jaebum, Larkin, Denis M., Auvil, Loretta, Capitanu, Boris, Ma, Jian, Lewin, Harris A., Qian, Xiaoju, Lang, Yongshan, Zhou, Ran, Wang, Lizhong, Wang, Kun, Xia, Jinquan, Liao, Shengguang, Pan, Shengkai, Lu, Xu, Hou, Haolong, Wang, Yan, Zang, Xuetao, Yin, Ye, Ma, Hui, Zhang, Jian, Wang, Zhaofeng, Zhang, Yingmei, Zhang, Dawei, Yonezawa, Takahiro, Hasegawa, Masami, Zhong, Yang, Liu, Wenbin, Zhang, Yan, Huang, Zhiyong, Zhang, Shengxiang, Long, Ruijun, Yang, Huanming, Lenstra, Johannes A., Cooper, David N., Wu, Yi, Wang, Jun, Shi, Peng, Wang, Jian, Liu, Jianquan, Wang, Junyis, LS IRAS Tox Algemeen, Faculty of Veterinary Medicine Research Groups, and Algemeen Onderzoek DGK

Subjects
Genetics
Abstract

Domestic yaks (Bos grunniens) provide meat and other necessities for Tibetans living at high altitude on the Qinghai-Tibetan Plateau and in adjacent regions. Comparison between yak and the closely related low-altitude cattle (Bos taurus) is informative in studying animal adaptation to high altitude. Here, we present the draft genome sequence of a female domestic yak generated using Illumina-based technology at 65-fold coverage. Genomic comparisons between yak and cattle identify an expansion in yak of gene families related to sensory perception and energy metabolism, as well as an enrichment of protein domains involved in sensing the extracellular environment and hypoxic stress. Positively selected and rapidly evolving genes in the yak lineage are also found to be significantly enriched in functional categories and pathways related to hypoxia and nutrition metabolism. These findings may have important implications for understanding adaptation to high altitude in other animal species and for hypoxia-related diseases in humans. © 2012 Nature America, Inc. All rights reserved.

Published
2012

5. Genome sequence of ground tit Pseudopodoces humilis and its adaptation to high altitude

Author

Cai, Qingle, Qian, Xiaoju, Lang, Yongshan, Luo, Yadan, Xu, Jiaohui, Pan, Shengkai, Hui, Yuanyuan, Gou, Caiyun, Cai, Yue, Hao, Meirong, Zhao, Jinyang, Wang, Songbo, Wang, Zhaobao, Zhang, Xinming, He, Rongjun, Liu, Jinchao, Luo, Longhai, Li, Yingrui, Wang, Jun, Cai, Qingle, Qian, Xiaoju, Lang, Yongshan, Luo, Yadan, Xu, Jiaohui, Pan, Shengkai, Hui, Yuanyuan, Gou, Caiyun, Cai, Yue, Hao, Meirong, Zhao, Jinyang, Wang, Songbo, Wang, Zhaobao, Zhang, Xinming, He, Rongjun, Liu, Jinchao, Luo, Longhai, Li, Yingrui, and Wang, Jun

Published
2013

6. The yak genome and adaptation to life at high altitude

Author

LS IRAS Tox Algemeen, Faculty of Veterinary Medicine Research Groups, Algemeen Onderzoek DGK, Qiu, Qiang, Zhang, Guojie, Ma, Tao, Qian, Wubin, Ye, Zhiqiang, Cao, Changchang, Hu, Quanjun, Kim, Jaebum, Larkin, Denis M., Auvil, Loretta, Capitanu, Boris, Ma, Jian, Lewin, Harris A., Qian, Xiaoju, Lang, Yongshan, Zhou, Ran, Wang, Lizhong, Wang, Kun, Xia, Jinquan, Liao, Shengguang, Pan, Shengkai, Lu, Xu, Hou, Haolong, Wang, Yan, Zang, Xuetao, Yin, Ye, Ma, Hui, Zhang, Jian, Wang, Zhaofeng, Zhang, Yingmei, Zhang, Dawei, Yonezawa, Takahiro, Hasegawa, Masami, Zhong, Yang, Liu, Wenbin, Zhang, Yan, Huang, Zhiyong, Zhang, Shengxiang, Long, Ruijun, Yang, Huanming, Lenstra, Johannes A., Cooper, David N., Wu, Yi, Wang, Jun, Shi, Peng, Wang, Jian, Liu, Jianquan, Wang, Junyis, LS IRAS Tox Algemeen, Faculty of Veterinary Medicine Research Groups, Algemeen Onderzoek DGK, Qiu, Qiang, Zhang, Guojie, Ma, Tao, Qian, Wubin, Ye, Zhiqiang, Cao, Changchang, Hu, Quanjun, Kim, Jaebum, Larkin, Denis M., Auvil, Loretta, Capitanu, Boris, Ma, Jian, Lewin, Harris A., Qian, Xiaoju, Lang, Yongshan, Zhou, Ran, Wang, Lizhong, Wang, Kun, Xia, Jinquan, Liao, Shengguang, Pan, Shengkai, Lu, Xu, Hou, Haolong, Wang, Yan, Zang, Xuetao, Yin, Ye, Ma, Hui, Zhang, Jian, Wang, Zhaofeng, Zhang, Yingmei, Zhang, Dawei, Yonezawa, Takahiro, Hasegawa, Masami, Zhong, Yang, Liu, Wenbin, Zhang, Yan, Huang, Zhiyong, Zhang, Shengxiang, Long, Ruijun, Yang, Huanming, Lenstra, Johannes A., Cooper, David N., Wu, Yi, Wang, Jun, Shi, Peng, Wang, Jian, Liu, Jianquan, and Wang, Junyis

Published
2012

7. Correction: The genome sequence of the ground tit Pseudopodoces humilis provides insights into its adaptation to high altitude

Author

Cai, Qingle, primary, Qian, Xiaoju, additional, Lang, Yongshan, additional, Luo, Yadan, additional, Xu, Jiaohui, additional, Pan, Shengkai, additional, Hui, Yuanyuan, additional, Gou, Caiyun, additional, Cai, Yue, additional, Hao, Meirong, additional, Zhao, Jinyang, additional, Wang, Songbo, additional, Wang, Zhaobao, additional, Zhang, Xinming, additional, He, Rongjun, additional, Liu, Jinchao, additional, Luo, Longhai, additional, Li, Yingrui, additional, and Wang, Jun, additional

Published
2014
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8. RNA sequencing reveals the complex regulatory network in the maize kernel

Author

Fu, Junjie, primary, Cheng, Yanbing, additional, Linghu, Jingjing, additional, Yang, Xiaohong, additional, Kang, Lin, additional, Zhang, Zuxin, additional, Zhang, Jie, additional, He, Cheng, additional, Du, Xuemei, additional, Peng, Zhiyu, additional, Wang, Bo, additional, Zhai, Lihong, additional, Dai, Changmin, additional, Xu, Jiabao, additional, Wang, Weidong, additional, Li, Xiangru, additional, Zheng, Jun, additional, Chen, Li, additional, Luo, Longhai, additional, Liu, Junjie, additional, Qian, Xiaoju, additional, Yan, Jianbing, additional, Wang, Jun, additional, and Wang, Guoying, additional

Published
2013
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9. Genome sequence of ground tit Pseudopodoces humilis and its adaptation to high altitude

Author

Cai, Qingle, primary, Qian, Xiaoju, additional, Lang, Yongshan, additional, Luo, Yadan, additional, Xu, Jiaohui, additional, Pan, Shengkai, additional, Hui, Yuanyuan, additional, Gou, Caiyun, additional, Cai, Yue, additional, Hao, Meirong, additional, Zhao, Jinyang, additional, Wang, Songbo, additional, Wang, Zhaobao, additional, Zhang, Xinming, additional, He, Rongjun, additional, Liu, Jinchao, additional, Luo, Longhai, additional, Li, Yingrui, additional, and Wang, Jun, additional

Published
2013
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10. The yak genome and adaptation to life at high altitude

Author

Qiu, Qiang, primary, Zhang, Guojie, additional, Ma, Tao, additional, Qian, Wubin, additional, Wang, Junyi, additional, Ye, Zhiqiang, additional, Cao, Changchang, additional, Hu, Quanjun, additional, Kim, Jaebum, additional, Larkin, Denis M, additional, Auvil, Loretta, additional, Capitanu, Boris, additional, Ma, Jian, additional, Lewin, Harris A, additional, Qian, Xiaoju, additional, Lang, Yongshan, additional, Zhou, Ran, additional, Wang, Lizhong, additional, Wang, Kun, additional, Xia, Jinquan, additional, Liao, Shengguang, additional, Pan, Shengkai, additional, Lu, Xu, additional, Hou, Haolong, additional, Wang, Yan, additional, Zang, Xuetao, additional, Yin, Ye, additional, Ma, Hui, additional, Zhang, Jian, additional, Wang, Zhaofeng, additional, Zhang, Yingmei, additional, Zhang, Dawei, additional, Yonezawa, Takahiro, additional, Hasegawa, Masami, additional, Zhong, Yang, additional, Liu, Wenbin, additional, Zhang, Yan, additional, Huang, Zhiyong, additional, Zhang, Shengxiang, additional, Long, Ruijun, additional, Yang, Huanming, additional, Wang, Jian, additional, Lenstra, Johannes A, additional, Cooper, David N, additional, Wu, Yi, additional, Wang, Jun, additional, Shi, Peng, additional, and Liu, Jianquan, additional

Published
2012
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12. Genome sequence of ground tit Pseudopodoces humilisand its adaptation to high altitude

Author

Cai, Qingle, Qian, Xiaoju, Lang, Yongshan, Luo, Yadan, Xu, Jiaohui, Pan, Shengkai, Hui, Yuanyuan, Gou, Caiyun, Cai, Yue, Hao, Meirong, Zhao, Jinyang, Wang, Songbo, Wang, Zhaobao, Zhang, Xinming, He, Rongjun, Liu, Jinchao, Luo, Longhai, Li, Yingrui, and Wang, Jun

Abstract

The mechanism of high-altitude adaptation has been studied in certain mammals. However, in avian species like the ground tit Pseudopodoces humilis, the adaptation mechanism remains unclear. The phylogeny of the ground tit is also controversial. Using next generation sequencing technology, we generated and assembled a draft genome sequence of the ground tit. The assembly contained 1.04 Gb of sequence that covered 95.4% of the whole genome and had higher N50 values, at the level of both scaffolds and contigs, than other sequenced avian genomes. About 1.7 million SNPs were detected, 16,998 protein-coding genes were predicted and 7% of the genome was identified as repeat sequences. Comparisons between the ground tit genome and other avian genomes revealed a conserved genome structure and confirmed the phylogeny of ground tit as not belonging to the Corvidae family. Gene family expansion and positively selected gene analysis revealed genes that were related to cardiac function. Our findings contribute to our understanding of the adaptation of this species to extreme environmental living conditions. Our data and analysis contribute to the study of avian evolutionary history and provide new insights into the adaptation mechanisms to extreme conditions in animals.

Published
2013
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