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1. The Impact of a High School-Based Positive Youth Development Program on Sexual Health Outcomes: Results from a Randomized Controlled Trial

Author

Walsh, Sarah, Jenner, Eric, Qaragholi, Noor, Henley, Catherine, Demby, Hilary, Leger, Rebekah, and Burgess, Kelly

Abstract

Background: Although positive youth development (PYD) programs have demonstrated effectiveness in improving adolescent reproductive health outcomes, there is a lack of evidence on effective school-based interventions designed especially for high school settings. This study examined the efficacy of Peer Group Connection (PGC-HS), a school-based PYD program, in improving sexual health outcomes for high school participants. Methods: A total of 1523 ninth-grade students at 18 schools were randomly assigned to be offered PGC-HS or a classes-as-usual control condition during 2016 to 2017 and 2017 to 2018 school years. Impacts were assessed on three confirmatory and 6 exploratory outcomes via self-reported participant questionnaire data collected at the beginning of 10th grade. Results: Although the offer of PGC-HS had no statistically detectable effect on confirmatory behavioral outcomes (sexual initiation, frequency of sex, and number of sexual partners) at 10th grade follow-up, causal impact estimates indicate that PGC-HS participants were less likely than control participants to ever have had vaginal sex. PGC-HS participants also scored higher on decision-making skills and perceived connection to peer connectedness. Conclusions: Results suggest that by building social and emotional skills and helping students form supportive peer relationships, PGC-HS may encourage students to make healthier choices and avoid risky behaviors during a critical period in high school, thus, reducing the risk of pregnancy.

Published
2022
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2. High PrEP uptake, adherence, persistence and effectiveness outcomes among young Thai men and transgender women who sell sex in Bangkok and Pattaya, Thailand: findings from the open-label combination HIV prevention effectiveness (COPE) study

Author

Beyrer, Chris, Wirtz, Andrea, Weir, Brian, Baral, Stefan, Decker, Michele, Hnin Mon, Sandra Hsu, Case, James, Dun, Chen, Truong, Jasmine, Qaragholi, Noor, Ngo, Julie, Sisel, Haley, Sirivongrangson, Pachara, Chua-Intra, Boosbun, Chitwarakorn, Anupong, Matsee, Wasin, Wongkiti, Pratakpong, Krasan, Chidanan, Chainuwong, Anchana, Imlimtharn, Nauwarat, Reansoi, Potcharawan, Watanatanyaporn, Teeraparp, Nuamlert, Jarupa, Namwong, Supannikar, Phetnark, Jutarat, Supasa, Wachirawit, Sueayot, Siriporn, Hickey, Andrew, Thigpen, Michael, Dunne, Eileen, Woodring, Joseph, Vu, Christie, O'Connor, Siobhan, Flaherty, Patrick, Holtz, Timothy, Chemnasiri, Tareerat, Varangrat, Anchalee, Warapornmongkholkul, Anchalee, Chanthaweesirirat, Anekpong, Thienkrua, Warunee, Sukwicha, Wichuda, Disprayoon, Pitthaya, Kamkong, Kanjana, Worrajittanon, Dararat, Na-Pompet, Supawadee, Sariwatta, Chonlanot, Oungprasertgul, Patnaree, Sittidech, Phanurassamee, Suksamosorn, Jirawat, Sujina, Kesinee, Ungsedhapand, Chaiwat, Chonwattana, Wannee, Kamchaithep, Nichnawee, Pattanasin, Sarika, Tatakham, Nongkran, Luechai, Pikunchai, Mock, Philip, Cadwell, Betsy, Shrestha, Ram, Balmongkol, Baranee, Raengsakulrach, Boonyos, Leelawiwat, Wanna, Suwannaphan, Wanna, Sriinsut, Achara, Wasinrapee, Punneeporn, Chanathalay, Pornchanok, Promda, Nutthawoot, Winaitham, Santi, Kongpechsatit, Oranuch, Auethavornanan, Kusuma, Tongtoyai, Jaray, Tararut, Pairote, McNamara, Atitaya, Mueanpai, Famui, Sakulploy, Natthaga, Pancharoen, Kanokpan, Utenpitak, Chariya, Fukuda, Caroline, Cherdtrakulkiat, Thitima, Janthiraj, Tanyawarin, Sriporn, Anuwat, Prathummart, Natee, Khongsom, Patsaraporn, Navanuch, Navakarn, Wongbenchaporn, Rinda, Peerapatdit, Chanya, Khlaimanee, Pechpailin, Niyamakom, Patcharat, Tippanont, Narongritt, Yafant, Somsak, Ruanpang, Tatchai, Pongthai, Siripak, Okanurak, Kamolnetr, Meeyai, Aronrag, Linjongrat, Danai, Panpet, Phubet, Fungfoosri, Orawan, Boonyawan, Prisana, Sangprasert, Theeranat, Inthanin, Natthawirojn, Sangiamjit, Teppanan, Saiwaew, Somporn, Pawong, Konlawat, Janyam, Surang, Phaengnongyang, Chamrong, Phunkron, Atachai, Srikrongthong, Denchai, Dokrak, Thanaphat, Meekrua, Phathranis, Sumalu, Saman, Kanlose, Cawee, Thapwong, Prasopsuk, Kaewboonta, Kritsanapol, Brutrat, Pornpichit, Watthanayeam, Waris, Udomjirasirichot, Apichat, Sriplienchan, Somchai, Poonkasetwattana, Midnight, Kongsakul, Silapakhon, Badorrek, Michael, Tran, Andrey, Figueiredo, Ryan, Soeparna, Safir, Keiangpa, Wattana, Tibamrung, Apiwit, Samana, Sunadda, Syahputra, Hidayah, Rattanawarawong, Worapon, Sullivan, Patrick, Valencia, Rachel, Sharma, Usha, Adeyeye, Adeola, Rooney, James, Hunchangsith, Pojjana, Wansom, Tanyaporn, Guadamuz, Thomas, Sohn, Annette, Weir, Brian W., Wirtz, Andrea L., Baral, Stefan D., Dunne, Eileen F., Thigpen, Michael C., Ngo, Julie P., Sisel, Haley I., Truong, Jasmine M., Rooney, James F., and Hickey, Andrew C.

Published
2023
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4. Transactional sex, HIV and health among young cisgender men and transgender women who have sex with men in Thailand

Author

Weir, Brian W., Dun, Chen, Wirtz, Andrea L., Mon, Sandra Hsu Hnin, Qaragholi, Noor, Chemnasiri, Tareerat, Pattanasin, Sarika, Sukwicha, Wichuda, Varangrat, Anchalee, Dunne, Eileen F., Holtz, Timothy H., Janyam, Surang, Jin, Harry, Linjongrat, Danai, Mock, Philip A., Thigpen, Michael C., Rooney, James F., Sullivan, Patrick S., Hickey, Andrew C., Sirivongrangson, Pachara, and Beyrer, Chris

Published
2022
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5. High PrEP uptake, adherence, persistence and effectiveness outcomes among young Thai men and transgender women who sell sex in Bangkok and Pattaya, Thailand: findings from the open-label combination HIV prevention effectiveness (COPE) study

Author

Weir, Brian W., primary, Wirtz, Andrea L., additional, Chemnasiri, Tareerat, additional, Baral, Stefan D., additional, Decker, Michele, additional, Dun, Chen, additional, Hnin Mon, Sandra Hsu, additional, Ungsedhapand, Chaiwat, additional, Dunne, Eileen F., additional, Woodring, Joseph, additional, Pattanasin, Sarika, additional, Sukwicha, Wichuda, additional, Thigpen, Michael C., additional, Varangrat, Anchalee, additional, Warapornmongkholkul, Anchalee, additional, O'Connor, Siobhan, additional, Ngo, Julie P., additional, Qaragholi, Noor, additional, Sisel, Haley I., additional, Truong, Jasmine M., additional, Janyam, Surang, additional, Linjongrat, Danai, additional, Sriplienchan, Somchai, additional, Sirivongrangson, Pachara, additional, Rooney, James F., additional, Sullivan, Patrick, additional, Chua-Intra, Boosbun, additional, Hickey, Andrew C., additional, Beyrer, Chris, additional, Wirtz, Andrea, additional, Weir, Brian, additional, Baral, Stefan, additional, Case, James, additional, Truong, Jasmine, additional, Ngo, Julie, additional, Sisel, Haley, additional, Chitwarakorn, Anupong, additional, Matsee, Wasin, additional, Wongkiti, Pratakpong, additional, Krasan, Chidanan, additional, Chainuwong, Anchana, additional, Imlimtharn, Nauwarat, additional, Reansoi, Potcharawan, additional, Watanatanyaporn, Teeraparp, additional, Nuamlert, Jarupa, additional, Namwong, Supannikar, additional, Phetnark, Jutarat, additional, Supasa, Wachirawit, additional, Sueayot, Siriporn, additional, Hickey, Andrew, additional, Thigpen, Michael, additional, Dunne, Eileen, additional, Vu, Christie, additional, Flaherty, Patrick, additional, Holtz, Timothy, additional, Chanthaweesirirat, Anekpong, additional, Thienkrua, Warunee, additional, Disprayoon, Pitthaya, additional, Kamkong, Kanjana, additional, Worrajittanon, Dararat, additional, Na-Pompet, Supawadee, additional, Sariwatta, Chonlanot, additional, Oungprasertgul, Patnaree, additional, Sittidech, Phanurassamee, additional, Suksamosorn, Jirawat, additional, Sujina, Kesinee, additional, Chonwattana, Wannee, additional, Kamchaithep, Nichnawee, additional, Tatakham, Nongkran, additional, Luechai, Pikunchai, additional, Mock, Philip, additional, Cadwell, Betsy, additional, Shrestha, Ram, additional, Balmongkol, Baranee, additional, Raengsakulrach, Boonyos, additional, Leelawiwat, Wanna, additional, Suwannaphan, Wanna, additional, Sriinsut, Achara, additional, Wasinrapee, Punneeporn, additional, Chanathalay, Pornchanok, additional, Promda, Nutthawoot, additional, Winaitham, Santi, additional, Kongpechsatit, Oranuch, additional, Auethavornanan, Kusuma, additional, Tongtoyai, Jaray, additional, Tararut, Pairote, additional, McNamara, Atitaya, additional, Mueanpai, Famui, additional, Sakulploy, Natthaga, additional, Pancharoen, Kanokpan, additional, Utenpitak, Chariya, additional, Fukuda, Caroline, additional, Cherdtrakulkiat, Thitima, additional, Janthiraj, Tanyawarin, additional, Sriporn, Anuwat, additional, Prathummart, Natee, additional, Khongsom, Patsaraporn, additional, Navanuch, Navakarn, additional, Wongbenchaporn, Rinda, additional, Peerapatdit, Chanya, additional, Khlaimanee, Pechpailin, additional, Niyamakom, Patcharat, additional, Tippanont, Narongritt, additional, Yafant, Somsak, additional, Ruanpang, Tatchai, additional, Pongthai, Siripak, additional, Okanurak, Kamolnetr, additional, Meeyai, Aronrag, additional, Panpet, Phubet, additional, Fungfoosri, Orawan, additional, Boonyawan, Prisana, additional, Sangprasert, Theeranat, additional, Inthanin, Natthawirojn, additional, Sangiamjit, Teppanan, additional, Saiwaew, Somporn, additional, Pawong, Konlawat, additional, Phaengnongyang, Chamrong, additional, Phunkron, Atachai, additional, Srikrongthong, Denchai, additional, Dokrak, Thanaphat, additional, Meekrua, Phathranis, additional, Sumalu, Saman, additional, Kanlose, Cawee, additional, Thapwong, Prasopsuk, additional, Kaewboonta, Kritsanapol, additional, Brutrat, Pornpichit, additional, Watthanayeam, Waris, additional, Udomjirasirichot, Apichat, additional, Poonkasetwattana, Midnight, additional, Kongsakul, Silapakhon, additional, Badorrek, Michael, additional, Tran, Andrey, additional, Figueiredo, Ryan, additional, Soeparna, Safir, additional, Keiangpa, Wattana, additional, Tibamrung, Apiwit, additional, Samana, Sunadda, additional, Syahputra, Hidayah, additional, Rattanawarawong, Worapon, additional, Valencia, Rachel, additional, Sharma, Usha, additional, Adeyeye, Adeola, additional, Rooney, James, additional, Hunchangsith, Pojjana, additional, Wansom, Tanyaporn, additional, Guadamuz, Thomas, additional, and Sohn, Annette, additional

Published
2023
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7. High PrEP Uptake, Adherence, Persistence and Effectiveness Outcomes Among Young Thai Men and Transgender Women Who Sell Sex in Bangkok and Pattaya, Thailand: Findings from the Open-Label Combination HIV Prevention Effectiveness (COPE) Study

Author

Weir, Brian W., primary, Wirtz, Andrea, additional, Chemnasiri, Tareerat, additional, Baral, Stefan, additional, Decker, Michele R., additional, Dun, Chen, additional, Mon, Sandra Hsu Hnin, additional, Ungsedhapand, Chaiwat, additional, Dunne, Eileen F., additional, Woodring, Joseph V., additional, Pattanasin, Sarika, additional, Sukwicha, Wichuda, additional, Thigpen, Michael C., additional, Varangrat, Anchalee, additional, Warapornmongkholkul, Anchalee, additional, O’Connor, Siobhan, additional, Ngo, Julie P., additional, Qaragholi, Noor, additional, Sisel, Haley I., additional, Truong, Jasmine M., additional, Janyam, Surang, additional, Linjongrat, Danai, additional, Sriplienchan, Somchai, additional, Sirivongrangson, Pachara, additional, Rooney, James F., additional, Sullivan, Patrick, additional, Chua-Intra, Boosbun, additional, Hickey, Andrew C., additional, and Beyrer, Chris, additional

Published
2022
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8. A systematic review of state and manufacturer physician payment disclosure websites: implications for implementation of the Sunshine Act

Author

Hwong, Alison R., Qaragholi, Noor, Carpenter, Daniel, Joffe, Steven, Campbell, Eric G., and Lehmann, Lisa Soleymani

Subjects
Financial disclosure -- Laws, regulations and rules -- Analysis, Physicians -- Information management -- Laws, regulations and rules -- Analysis, Online health care information services -- Analysis -- Laws, regulations and rules, Patient Protection and Affordable Care Act, Health, Law, Government regulation, Company systems management, Online health care service, Analysis, Information management, Laws, regulations and rules
Abstract

Introduction Public disclosure of industry payments to physicians is one way to address financial conflicts of interest in medicine. (1) As part of the Patient Protection and Affordable Care Act, [...]

Published
2014

10. High PrEP uptake, adherence, persistence and effectiveness outcomes among young Thai men and transgender women who sell sex in Bangkok and Pattaya, Thailand: findings from the open-label combination HIV prevention effectiveness (COPE) study.

Author

Weir BW, Wirtz AL, Chemnasiri T, Baral SD, Decker M, Dun C, Hnin Mon SH, Ungsedhapand C, Dunne EF, Woodring J, Pattanasin S, Sukwicha W, Thigpen MC, Varangrat A, Warapornmongkholkul A, O'Connor S, Ngo JP, Qaragholi N, Sisel HI, Truong JM, Janyam S, Linjongrat D, Sriplienchan S, Sirivongrangson P, Rooney JF, Sullivan P, Chua-Intra B, Hickey AC, and Beyrer C

Abstract

Background: Daily oral pre-exposure prophylaxis (PrEP) is effective in preventing HIV infection, but no study has evaluated combination prevention interventions with PrEP for transgender women (TGW) and men who have sex with men (MSM) who sell sex., Methods: The Combination Prevention Effectiveness (COPE) study was a community-based, non-randomized implementation study in Bangkok and Pattaya, Thailand. Participants were HIV-negative MSM and TGW aged 18-26 years who reported exchanging sex with men in the prior 12 months and who met 2014 U.S. Public Health Service PrEP eligibility criteria. The intervention included quarterly HIV testing, semiannual testing for sexually transmitted infections, provision of condoms with lubricant, and the opportunity to initiate or end daily oral PrEP use at any time during study participation. Participants taking PrEP received monthly adherence counseling and short message service reminders. The primary outcome was HIV incidence rate ratio (IRR) on PrEP vs. not on PrEP. Secondary outcomes were PrEP initiation, PrEP use at 12 months, and PrEP adherence., Findings: From October 2017 to August 2019, 846 participants were enrolled: 531 (62.8%) immediately initiated PrEP; 104 (12.3%) subsequently initiated PrEP, and 211 (24.9%) never initiated PrEP. Among those initiating PrEP within 30 days of enrollment; 85.9% were on PrEP at the 12-months. When taking PrEP, participants reported adherent PrEP use at 94.2% of quarterly assessments. Ten HIV seroconversions occurred without PrEP use (incidence rate [IR] = 3.42 per 100 person-years [PY]; 95% CI = 1.64-6.30), while zero cases occurred with PrEP use (IR = 0.0 per 100PY; 95% CI = 0.0-0.62), with IRR = 0.0 (95% CI = 0.0-0.22; p < 0.001)., Interpretation: Young Thai MSM and TGW who exchange sex can have high PrEP uptake, persistence and adherence, and low HIV incidence when offered in supportive community-based settings., Funding: U.S. National Institute of Allergy and Infectious Diseases; Centers for Disease Control and Prevention., Competing Interests: The study was supported by an R01 from NIAID, NIH (1R01AI118505-01A1) and the CDC Division of HIV Prevention. The study drug, Truvada®, was manufactured and donated by Gilead Sciences, Inc. Gilead Sciences, Inc. had no role in the design of the study nor in the interpretation of study results. The findings and conclusions presented in this paper are those of the authors and do not necessarily represent the views of the NIH, the US CDC, or 10.13039/100007197U.S. Public Health Service. Patrick Sullivan reports support from NIH, CDC, Merck, Gilead Sciences, ViiV Healthcare, Molecular Testing Labs, and Elsevier. James F. Rooney reports support from Gilead Sciences. Rest of the authors declare no competing interests., (© 2023 The Author(s).)

Published
2023
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