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3. Evolving Trends in the Management of Acute Appendicitis During COVID-19 Waves: The ACIE Appy II Study

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Pata, F, Di Martino, M, Podda, M, Di Saverio, S, Ielpo, B, Pellino, G, Julio, A, Alshamrani, A, Alturkistani, A, Alghamdi, A, Almalki, A, Orengia, A, Kuvvetli, A, Pisanu, A, Smith, A, Trevino Figueroa, A, Nacion, A, Alhazmi, A, Bouhuwaish, A, Khalid, A, Alsufyani, A, Rubio, A, Bavikatte, A, Kumar, A, Jamiri, A, de San Ildefonso Pereira, A, Porcu, A, Sartori, A, Rocca, A, Sretenovic, A, Anselmo, A, De Luca, A, Charalabopoulos, A, Tzivanakis, A, Bandin, A, Najar, A, Frontali, A, Faisal, A, Roldan, A, Hamid, A, Andre, A, Minaya-Bravo, A, Das, A, Bondurri, A, Costanzi, A, Lucchi, A, Mihailescu, A, Police, A, Zuchini, A, Romano, A, Iossa, A, Chessa, A, Tromba, A, Castaldi, A, Brillantino, A, Ferronetti, A, Giuliani, A, Ramos-De la Medina, A, Tarasconi, A, Picciariello, A, Ioannidis, A, Leppaniemi, A, Rashid, A, Mitul, A, Mehraj, A, Laharwal, A, Iqbal, A, Liarakos, A, Marinis, A, de Andres-Asenjo, B, Matias-Garcia, B, De Simone, B, Creavin, B, Stubbs, B, Goh, B, Jovanovic, B, Sensi, B, Gazia, C, Cerdan, C, Diaz, C, Chacon, C, Yanez, C, Faro, C, Reinke, C, Dominguez, C, Paranjape, C, Thomas, C, Fung, C, De Lucia, C, Jennifer, C, Ovalle-Chao, C, Guerci, C, Kenington, C, Gica, C, Folliero, C, Varela, C, Popowich, D, Delogu, D, Zigiotto, D, Vinci, D, D'Antonio, D, Merlini, D, Moro-Valdezate, D, Keller, D, Nicolaescu, D, Sasia, D, Rodas, E, Linardoutsos, D, Russello, D, Najar-Castaneda, P, Stavrou, H, Rosso, E, Saladino, E, Ricciardi, E, Smith-Singares, E, Baili, E, Douka, E, Guaitoli, E, Francone, E, Vaterlini, E, Pierobon, E, Morales, E, Ros, E, Benzoni, E, Erdas, E, Pinotti, E, Colas-Ruiz, E, Laterza, E, Foianini, E, Cardamone, E, Licardie, E, Marino, F, Alsofyani, F, Qahtani, F, Khan, F, Maraska, F, Saliu, F, Madrid, F, Rosa, F, Luvisetto, F, Alconchel, F, Pareja-Ciuro, F, Neves, F, Agresta, F, Cordera, F, Pardo, F, Mendoza-Moreno, F, Munoz-Flores, F, Silvestri, F, Tropeano, F, Pecchini, F, Serio, F, Colombo, F, Di Marzo, F, Ferrara, F, Lancellotti, F, Litta, F, Martini, F, Roscio, F, Blanco-Antona, F, Barcenas, F, Schlottmann, F, Herrera-Almario, G, van Ramshorst, G, Gallo, G, Luglio, G, Kampouroglou, G, Papadopoulos, G, Arredondo, G, Calini, G, Formisano, G, Galiffa, G, Palini, G, Colucci, G, Pagano, G, Vanni, G, Pattacini, G, Gravante, G, Lisi, G, Bellanova, G, De Nobili, G, Necchi, G, Sinibaldi, G, Bacchiocchi, G, Bagaglini, G, Maggi, G, Izzo, G, Argenio, G, Brisinda, G, Esposito, G, Frazzetta, G, De Luca, G, Nigri, G, Sica, G, Martin-Martin, G, Ugon, G, Martinez-Mier, G, Machain Vega, G, Nari, G, Nikaj, H, Neri, I, San Roman, I, Fidoshev, I, Martinez, I, Negoi, I, Ortega, I, Vicente Rodriguez, I, Cornejo, I, Mora-Guzman, I, al-Najami, I, Romic, I, Balciscueta, I, Olivier, J, Lammel-Lindemann, J, Dziakova, J, Salinas, J, Jovanovic, J, Reyes, J, Salas, J, Diaz-Elizondo, J, Parreira, J, Bellido, J, Salamea, J, Martin del Olmo, J, Ordonez, J, Junaid, S, Davies, J, Sahnan, K, Bekele, K, Voon, K, Siragusa, L, Petagna, L, Ferrario, L, Giordano, L, Nespoli, L, Pio, L, Moletta, L, Curella, L, Taglietti, L, Bonavina, L, Conti, L, Perez-Sanchez, L, Cabrera Vargas, L, Sanchez-Guillen, L, Tallon-Aguilar, L, Khan, M, Spampinato, M, Viola, M, Malet, M, Angrisani, M, Calussi, M, Catarci, M, Giordano, M, Materazzo, M, Milone, M, Pellicciaro, M, Marino, M, Moreno Villamizar, M, Lolli, M, Bellini, M, Lemma, M, Chiarello, M, Montes-Manrique, M, Rodriguez-Lopez, M, Serradilla-Martin, M, Peter, M, Paniagua-Garcia-Senorans, M, Rutegard, M, Salo, M, Silveri, M, Veroux, M, Nardi, M, Rottoli, M, Tolonen, M, Pedraza Ciro, M, Zuluaga, M, Iacobone, M, Montuori, M, Ali, M, Garcia Dominguez, M, Paola, M, Piccoli, M, Campanelli, M, De Rosa, M, Manigrasso, M, Maruccia, M, Torre, M, Zuolo, M, Pera, M, Weerasekera, M, Prieto, M, Thway, M, Shaat, M, Azfar, M, Shalaby, M, Raza, M, Younis, M, Elhadi, M, Althomali, M, Al Amri, N, Dudi-Venkata, N, Alselaim, N, Smart, N, Trelles, N, Falco, N, Petrucciani, N, Antonacci, N, Cillara, N, Gica, N, Pecorelli, N, Tamini, N, Machairas, N, Feituri, N, Ortega Torrecilla, N, Avila Mercado, O, Alaamer, O, Irkorucu, O, Alsherif, O, Buonomi, O, Valles-Guerra, O, Ioannidis, O, Hernandez Palmas, O, Sanz Guadarrama, O, Bozbiyik, O, Rodrigues, P, Milito, P, Panaccio, P, Dorovinis, P, Prieto, P, Baroffio, P, Marsanic, P, Ajawin, P, Koh, P, Anoldo, P, Major, P, Alharthi, Q, Lui, R, Caruso, R, Brady, R, Rattan, R, Singhal, R, Angelico, R, Isernia, R, Tutino, R, Peltrini, R, Tejos, R, Fajardo, R, Elia, R, Morales-Conde, S, Benli, S, Fuentes, S, de las Casas, S, de Guzman Aragon, S, Vertaldi, S, Awad, S, Gentilli, S, Weckmann Lujan, S, Tayar, S, Althobaiti, S, Di Giovanni, S, Ghedan, S, Perez-Bertolez, S, Chiappetta, S, Delis, S, Scaringi, S, Cetinkunar, S, Kykalos, S, Muhammad Ali, S, Krivan, S, Fung, T, Delko, T, Nicolas Lopez, T, De Campos, T, Calderon Duque, T, Perra, T, Liakakos, T, Daskalakis, T, Koeter, T, Zalla, T, Gonzalez, T, Campagnaro, T, Oumar, T, Grossi, U, Sosa, V, Testa, V, Tomajer, V, Andriola, V, Tonini, V, Celentano, V, Voglino, V, Katta, V, Garcia Orozco, V, Turrado-Rodriguez, V, Visag-Castillo, V, Graham, V, Rachkov, V, Papagni, V, Vigorita, V, Jimenez Carneros, V, Bellato, V, Bechstein, W, Altinel, Y, Balciscueta, Z, Pata F., Di Martino M., Podda M., Di Saverio S., Ielpo B., Pellino G., Julio A., Alshamrani A., Alturkistani A., Alghamdi A., Almalki A., Orengia A., Kuvvetli A., Pisanu A., Smith A., Trevino Figueroa A. M., Nacion A. J., Alhazmi A., Bouhuwaish A., Khalid A., Alsufyani A., Rubio A. V., Bavikatte A., Kumar A., Jamiri A. -R., de San Ildefonso Pereira A., Porcu A., Sartori A., Rocca A., Sretenovic A., Anselmo A., De Luca A., Charalabopoulos A., Tzivanakis A., Bandin A., Najar A., Frontali A., Faisal A., Roldan A. M., Hamid A., Andre A., Minaya-Bravo A., Das A., Bondurri A., Costanzi A., Lucchi A., Mihailescu A., Police A., Zuchini A. M., Romano A., Iossa A., Chessa A., Tromba A., Castaldi A., Brillantino A., Ferronetti A., Giuliani A., Ramos-De la Medina A., Tarasconi A., Picciariello A., Ioannidis A., Leppaniemi A., Rashid A., Mitul A. R., Mehraj A., laharwal A., Iqbal A., Liarakos A., Marinis A., de Andres-Asenjo B., Matias-Garcia B., De Simone B., Creavin B., Stubbs B., Goh B., Jovanovic B., Sensi B., Gazia C., Cerdan C., Diaz C. J. G., Chacon C. P., Yanez C., Faro C. L., Reinke C., Dominguez C., Paranjape C., Thomas C., Fung C. C., De Lucia C., Jennifer C. H. F., Ovalle-Chao C., Guerci C., Kenington C., Gica C., Folliero C., Varela C., Popowich D., Delogu D., Zigiotto D., Vinci D., D'Antonio D., Merlini D. A., Merlini D., Moro-Valdezate D., Keller D., Nicolaescu D. C., Sasia D., Rodas E., Linardoutsos D., Russello D., Najar-Castaneda P. A., Stavrou H. G., Rosso E., Saladino E., Ricciardi E., Smith-Singares E., Baili E., Douka E., Guaitoli E., Francone E., Vaterlini E. M., Pierobon E. S., Morales E., Ros E. P., Benzoni E., Erdas E., Pinotti E., Colas-Ruiz E., Laterza E., Foianini E., Cardamone E., Licardie E., Marino F., Alsofyani F., Qahtani F., Khan F., Maraska F., Saliu F., Madrid F., Rosa F., Luvisetto F., Alconchel F., Pareja-Ciuro F., Neves F., Agresta F., Cordera F., Pardo F., Mendoza-Moreno F., Munoz-Flores F., Silvestri F. M., Tropeano F. P., Pecchini F., Serio F., Colombo F., Di Marzo F., Ferrara F., Lancellotti F., Litta F., Martini F., Roscio F., Blanco-Antona F., Barcenas F. J. Q., Schlottmann F., Herrera-Almario G., van Ramshorst G., Gallo G., Luglio G., Kampouroglou G., Papadopoulos G., Arredondo G., Calini G., Formisano G., Galiffa G., Palini G. M., Colucci G., Pagano G., Vanni G., Pattacini G. C., Gravante G., Lisi G., Bellanova G., De Nobili G., Necchi G. S., Sinibaldi G., Bacchiocchi G., Bagaglini G., Maggi G., Izzo G., Argenio G., Brisinda G., Esposito G., Frazzetta G., De Luca G. M., Nigri G., Sica G., Martin-Martin G., Ugon G. A., Martinez-Mier G., Machain Vega G. M., Nari G., Nikaj H., Neri I., San Roman I. A., Fidoshev I., Martinez I., Negoi I., Ortega I., Vicente Rodriguez I., Cornejo I., Mora-Guzman I., al-Najami I., Romic I., Balciscueta I., Olivier J., Lammel-Lindemann J., Dziakova J., Salinas J., Jovanovic J. P., Reyes J. A. S., Salas J., Diaz-Elizondo J. A., Parreira J. G., Bellido J., Salamea J., Martin del Olmo J. C., Ordonez J. M., Junaid S., Davies J., Sahnan K., Bekele K., Voon K., Siragusa L., Petagna L., Ferrario L., Giordano L., Nespoli L., Pio L., Moletta L., Curella L., Taglietti L., Bonavina L., Conti L., Perez-Sanchez L. E., Cabrera Vargas L. F., Sanchez-Guillen L., Tallon-Aguilar L., Khan M., Spampinato M. G., Viola M., Malet M. V., Angrisani M., Calussi M., Catarci M., Giordano M., Materazzo M., Milone M., Pellicciaro M., Marino M. V., Moreno Villamizar M. D., Lolli M. G., Bellini M. I., Lemma M., Chiarello M. M., Montes-Manrique M., Rodriguez-Lopez M., Serradilla-Martin M., Peter M., Paniagua-Garcia-Senorans M., Rutegard M., Salo M., Silveri M., Veroux M., Nardi M., Rottoli M., Tolonen M., Pedraza Ciro M., Zuluaga M., Iacobone M., Montuori M., Ali M., Garcia Dominguez M., Paola M. M., Piccoli M., Campanelli M., De Rosa M., Manigrasso M., Maruccia M., Torre M., Zuolo M., Pera M., Weerasekera M., Prieto M., Thway M. M., Shaat M., Azfar M., Shalaby M., Raza M. A., Younis M. U., Elhadi M., AlThomali M., Al Amri N., Dudi-Venkata N., Alselaim N., Smart N., Trelles N., Falco N., Petrucciani N., Antonacci N., Cillara N., Gica N., Pecorelli N., Tamini N., Machairas N., Feituri N., Ortega Torrecilla N., Avila Mercado O., AlAamer O., Irkorucu O., Alsherif O., Buonomi O. C., Valles-Guerra O., Ioannidis O., Hernandez Palmas O. I., Sanz Guadarrama O., Bozbiyik O., Rodrigues P., Milito P., Panaccio P., Dorovinis P., Prieto P., Baroffio P., Marsanic P., Ajawin P., Koh P. S., Anoldo P., Major P., Alharthi Q., Lui R., Caruso R., Brady R., Rattan R., Singhal R., Angelico R., Isernia R. M., Tutino R., Peltrini R., Tejos R., Fajardo R., Elia R., Morales-Conde S., Benli S., Fuentes S., de las Casas S. G., de Guzman Aragon S. O., Vertaldi S., Awad S., Gentilli S., Weckmann Lujan S. A., Tayar S., Althobaiti S., Di Giovanni S., Ghedan S., Perez-Bertolez S., Chiappetta S., Delis S., Scaringi S., Cetinkunar S., Kykalos S., Muhammad Ali S., Krivan S., Fung T. L. D., Delko T., Nicolas Lopez T., De Campos T., Calderon Duque T., Perra T., Liakakos T., Daskalakis T., Koeter T., Zalla T., Gonzalez T. E., Campagnaro T., Oumar T. A., Grossi U., Sosa V., Testa V., Tomajer V., Andriola V., Tonini V., Celentano V., Voglino V., Katta V. R., Garcia Orozco V. H., Turrado-Rodriguez V., Visag-Castillo V., Graham V., Rachkov V., Papagni V., Vigorita V., Jimenez Carneros V., Bellato V., Bechstein W., Altinel Y., Balciscueta Z., Pata, F, Di Martino, M, Podda, M, Di Saverio, S, Ielpo, B, Pellino, G, Julio, A, Alshamrani, A, Alturkistani, A, Alghamdi, A, Almalki, A, Orengia, A, Kuvvetli, A, Pisanu, A, Smith, A, Trevino Figueroa, A, Nacion, A, Alhazmi, A, Bouhuwaish, A, Khalid, A, Alsufyani, A, Rubio, A, Bavikatte, A, Kumar, A, Jamiri, A, de San Ildefonso Pereira, A, Porcu, A, Sartori, A, Rocca, A, Sretenovic, A, Anselmo, A, De Luca, A, Charalabopoulos, A, Tzivanakis, A, Bandin, A, Najar, A, Frontali, A, Faisal, A, Roldan, A, Hamid, A, Andre, A, Minaya-Bravo, A, Das, A, Bondurri, A, Costanzi, A, Lucchi, A, Mihailescu, A, Police, A, Zuchini, A, Romano, A, Iossa, A, Chessa, A, Tromba, A, Castaldi, A, Brillantino, A, Ferronetti, A, Giuliani, A, Ramos-De la Medina, A, Tarasconi, A, Picciariello, A, Ioannidis, A, Leppaniemi, A, Rashid, A, Mitul, A, Mehraj, A, Laharwal, A, Iqbal, A, Liarakos, A, Marinis, A, de Andres-Asenjo, B, Matias-Garcia, B, De Simone, B, Creavin, B, Stubbs, B, Goh, B, Jovanovic, B, Sensi, B, Gazia, C, Cerdan, C, Diaz, C, Chacon, C, Yanez, C, Faro, C, Reinke, C, Dominguez, C, Paranjape, C, Thomas, C, Fung, C, De Lucia, C, Jennifer, C, Ovalle-Chao, C, Guerci, C, Kenington, C, Gica, C, Folliero, C, Varela, C, Popowich, D, Delogu, D, Zigiotto, D, Vinci, D, D'Antonio, D, Merlini, D, Moro-Valdezate, D, Keller, D, Nicolaescu, D, Sasia, D, Rodas, E, Linardoutsos, D, Russello, D, Najar-Castaneda, P, Stavrou, H, Rosso, E, Saladino, E, Ricciardi, E, Smith-Singares, E, Baili, E, Douka, E, Guaitoli, E, Francone, E, Vaterlini, E, Pierobon, E, Morales, E, Ros, E, Benzoni, E, Erdas, E, Pinotti, E, Colas-Ruiz, E, Laterza, E, Foianini, E, Cardamone, E, Licardie, E, Marino, F, Alsofyani, F, Qahtani, F, Khan, F, Maraska, F, Saliu, F, Madrid, F, Rosa, F, Luvisetto, F, Alconchel, F, Pareja-Ciuro, F, Neves, F, Agresta, F, Cordera, F, Pardo, F, Mendoza-Moreno, F, Munoz-Flores, F, Silvestri, F, Tropeano, F, Pecchini, F, Serio, F, Colombo, F, Di Marzo, F, Ferrara, F, Lancellotti, F, Litta, F, Martini, F, Roscio, F, Blanco-Antona, F, Barcenas, F, Schlottmann, F, Herrera-Almario, G, van Ramshorst, G, Gallo, G, Luglio, G, Kampouroglou, G, Papadopoulos, G, Arredondo, G, Calini, G, Formisano, G, Galiffa, G, Palini, G, Colucci, G, Pagano, G, Vanni, G, Pattacini, G, Gravante, G, Lisi, G, Bellanova, G, De Nobili, G, Necchi, G, Sinibaldi, G, Bacchiocchi, G, Bagaglini, G, Maggi, G, Izzo, G, Argenio, G, Brisinda, G, Esposito, G, Frazzetta, G, De Luca, G, Nigri, G, Sica, G, Martin-Martin, G, Ugon, G, Martinez-Mier, G, Machain Vega, G, Nari, G, Nikaj, H, Neri, I, San Roman, I, Fidoshev, I, Martinez, I, Negoi, I, Ortega, I, Vicente Rodriguez, I, Cornejo, I, Mora-Guzman, I, al-Najami, I, Romic, I, Balciscueta, I, Olivier, J, Lammel-Lindemann, J, Dziakova, J, Salinas, J, Jovanovic, J, Reyes, J, Salas, J, Diaz-Elizondo, J, Parreira, J, Bellido, J, Salamea, J, Martin del Olmo, J, Ordonez, J, Junaid, S, Davies, J, Sahnan, K, Bekele, K, Voon, K, Siragusa, L, Petagna, L, Ferrario, L, Giordano, L, Nespoli, L, Pio, L, Moletta, L, Curella, L, Taglietti, L, Bonavina, L, Conti, L, Perez-Sanchez, L, Cabrera Vargas, L, Sanchez-Guillen, L, Tallon-Aguilar, L, Khan, M, Spampinato, M, Viola, M, Malet, M, Angrisani, M, Calussi, M, Catarci, M, Giordano, M, Materazzo, M, Milone, M, Pellicciaro, M, Marino, M, Moreno Villamizar, M, Lolli, M, Bellini, M, Lemma, M, Chiarello, M, Montes-Manrique, M, Rodriguez-Lopez, M, Serradilla-Martin, M, Peter, M, Paniagua-Garcia-Senorans, M, Rutegard, M, Salo, M, Silveri, M, Veroux, M, Nardi, M, Rottoli, M, Tolonen, M, Pedraza Ciro, M, Zuluaga, M, Iacobone, M, Montuori, M, Ali, M, Garcia Dominguez, M, Paola, M, Piccoli, M, Campanelli, M, De Rosa, M, Manigrasso, M, Maruccia, M, Torre, M, Zuolo, M, Pera, M, Weerasekera, M, Prieto, M, Thway, M, Shaat, M, Azfar, M, Shalaby, M, Raza, M, Younis, M, Elhadi, M, Althomali, M, Al Amri, N, Dudi-Venkata, N, Alselaim, N, Smart, N, Trelles, N, Falco, N, Petrucciani, N, Antonacci, N, Cillara, N, Gica, N, Pecorelli, N, Tamini, N, Machairas, N, Feituri, N, Ortega Torrecilla, N, Avila Mercado, O, Alaamer, O, Irkorucu, O, Alsherif, O, Buonomi, O, Valles-Guerra, O, Ioannidis, O, Hernandez Palmas, O, Sanz Guadarrama, O, Bozbiyik, O, Rodrigues, P, Milito, P, Panaccio, P, Dorovinis, P, Prieto, P, Baroffio, P, Marsanic, P, Ajawin, P, Koh, P, Anoldo, P, Major, P, Alharthi, Q, Lui, R, Caruso, R, Brady, R, Rattan, R, Singhal, R, Angelico, R, Isernia, R, Tutino, R, Peltrini, R, Tejos, R, Fajardo, R, Elia, R, Morales-Conde, S, Benli, S, Fuentes, S, de las Casas, S, de Guzman Aragon, S, Vertaldi, S, Awad, S, Gentilli, S, Weckmann Lujan, S, Tayar, S, Althobaiti, S, Di Giovanni, S, Ghedan, S, Perez-Bertolez, S, Chiappetta, S, Delis, S, Scaringi, S, Cetinkunar, S, Kykalos, S, Muhammad Ali, S, Krivan, S, Fung, T, Delko, T, Nicolas Lopez, T, De Campos, T, Calderon Duque, T, Perra, T, Liakakos, T, Daskalakis, T, Koeter, T, Zalla, T, Gonzalez, T, Campagnaro, T, Oumar, T, Grossi, U, Sosa, V, Testa, V, Tomajer, V, Andriola, V, Tonini, V, Celentano, V, Voglino, V, Katta, V, Garcia Orozco, V, Turrado-Rodriguez, V, Visag-Castillo, V, Graham, V, Rachkov, V, Papagni, V, Vigorita, V, Jimenez Carneros, V, Bellato, V, Bechstein, W, Altinel, Y, Balciscueta, Z, Pata F., Di Martino M., Podda M., Di Saverio S., Ielpo B., Pellino G., Julio A., Alshamrani A., Alturkistani A., Alghamdi A., Almalki A., Orengia A., Kuvvetli A., Pisanu A., Smith A., Trevino Figueroa A. M., Nacion A. J., Alhazmi A., Bouhuwaish A., Khalid A., Alsufyani A., Rubio A. V., Bavikatte A., Kumar A., Jamiri A. -R., de San Ildefonso Pereira A., Porcu A., Sartori A., Rocca A., Sretenovic A., Anselmo A., De Luca A., Charalabopoulos A., Tzivanakis A., Bandin A., Najar A., Frontali A., Faisal A., Roldan A. M., Hamid A., Andre A., Minaya-Bravo A., Das A., Bondurri A., Costanzi A., Lucchi A., Mihailescu A., Police A., Zuchini A. M., Romano A., Iossa A., Chessa A., Tromba A., Castaldi A., Brillantino A., Ferronetti A., Giuliani A., Ramos-De la Medina A., Tarasconi A., Picciariello A., Ioannidis A., Leppaniemi A., Rashid A., Mitul A. R., Mehraj A., laharwal A., Iqbal A., Liarakos A., Marinis A., de Andres-Asenjo B., Matias-Garcia B., De Simone B., Creavin B., Stubbs B., Goh B., Jovanovic B., Sensi B., Gazia C., Cerdan C., Diaz C. J. G., Chacon C. P., Yanez C., Faro C. L., Reinke C., Dominguez C., Paranjape C., Thomas C., Fung C. C., De Lucia C., Jennifer C. H. F., Ovalle-Chao C., Guerci C., Kenington C., Gica C., Folliero C., Varela C., Popowich D., Delogu D., Zigiotto D., Vinci D., D'Antonio D., Merlini D. A., Merlini D., Moro-Valdezate D., Keller D., Nicolaescu D. C., Sasia D., Rodas E., Linardoutsos D., Russello D., Najar-Castaneda P. A., Stavrou H. G., Rosso E., Saladino E., Ricciardi E., Smith-Singares E., Baili E., Douka E., Guaitoli E., Francone E., Vaterlini E. M., Pierobon E. S., Morales E., Ros E. P., Benzoni E., Erdas E., Pinotti E., Colas-Ruiz E., Laterza E., Foianini E., Cardamone E., Licardie E., Marino F., Alsofyani F., Qahtani F., Khan F., Maraska F., Saliu F., Madrid F., Rosa F., Luvisetto F., Alconchel F., Pareja-Ciuro F., Neves F., Agresta F., Cordera F., Pardo F., Mendoza-Moreno F., Munoz-Flores F., Silvestri F. M., Tropeano F. P., Pecchini F., Serio F., Colombo F., Di Marzo F., Ferrara F., Lancellotti F., Litta F., Martini F., Roscio F., Blanco-Antona F., Barcenas F. J. Q., Schlottmann F., Herrera-Almario G., van Ramshorst G., Gallo G., Luglio G., Kampouroglou G., Papadopoulos G., Arredondo G., Calini G., Formisano G., Galiffa G., Palini G. M., Colucci G., Pagano G., Vanni G., Pattacini G. C., Gravante G., Lisi G., Bellanova G., De Nobili G., Necchi G. S., Sinibaldi G., Bacchiocchi G., Bagaglini G., Maggi G., Izzo G., Argenio G., Brisinda G., Esposito G., Frazzetta G., De Luca G. M., Nigri G., Sica G., Martin-Martin G., Ugon G. A., Martinez-Mier G., Machain Vega G. M., Nari G., Nikaj H., Neri I., San Roman I. A., Fidoshev I., Martinez I., Negoi I., Ortega I., Vicente Rodriguez I., Cornejo I., Mora-Guzman I., al-Najami I., Romic I., Balciscueta I., Olivier J., Lammel-Lindemann J., Dziakova J., Salinas J., Jovanovic J. P., Reyes J. A. S., Salas J., Diaz-Elizondo J. A., Parreira J. G., Bellido J., Salamea J., Martin del Olmo J. C., Ordonez J. M., Junaid S., Davies J., Sahnan K., Bekele K., Voon K., Siragusa L., Petagna L., Ferrario L., Giordano L., Nespoli L., Pio L., Moletta L., Curella L., Taglietti L., Bonavina L., Conti L., Perez-Sanchez L. E., Cabrera Vargas L. F., Sanchez-Guillen L., Tallon-Aguilar L., Khan M., Spampinato M. G., Viola M., Malet M. V., Angrisani M., Calussi M., Catarci M., Giordano M., Materazzo M., Milone M., Pellicciaro M., Marino M. V., Moreno Villamizar M. D., Lolli M. G., Bellini M. I., Lemma M., Chiarello M. M., Montes-Manrique M., Rodriguez-Lopez M., Serradilla-Martin M., Peter M., Paniagua-Garcia-Senorans M., Rutegard M., Salo M., Silveri M., Veroux M., Nardi M., Rottoli M., Tolonen M., Pedraza Ciro M., Zuluaga M., Iacobone M., Montuori M., Ali M., Garcia Dominguez M., Paola M. M., Piccoli M., Campanelli M., De Rosa M., Manigrasso M., Maruccia M., Torre M., Zuolo M., Pera M., Weerasekera M., Prieto M., Thway M. M., Shaat M., Azfar M., Shalaby M., Raza M. A., Younis M. U., Elhadi M., AlThomali M., Al Amri N., Dudi-Venkata N., Alselaim N., Smart N., Trelles N., Falco N., Petrucciani N., Antonacci N., Cillara N., Gica N., Pecorelli N., Tamini N., Machairas N., Feituri N., Ortega Torrecilla N., Avila Mercado O., AlAamer O., Irkorucu O., Alsherif O., Buonomi O. C., Valles-Guerra O., Ioannidis O., Hernandez Palmas O. I., Sanz Guadarrama O., Bozbiyik O., Rodrigues P., Milito P., Panaccio P., Dorovinis P., Prieto P., Baroffio P., Marsanic P., Ajawin P., Koh P. S., Anoldo P., Major P., Alharthi Q., Lui R., Caruso R., Brady R., Rattan R., Singhal R., Angelico R., Isernia R. M., Tutino R., Peltrini R., Tejos R., Fajardo R., Elia R., Morales-Conde S., Benli S., Fuentes S., de las Casas S. G., de Guzman Aragon S. O., Vertaldi S., Awad S., Gentilli S., Weckmann Lujan S. A., Tayar S., Althobaiti S., Di Giovanni S., Ghedan S., Perez-Bertolez S., Chiappetta S., Delis S., Scaringi S., Cetinkunar S., Kykalos S., Muhammad Ali S., Krivan S., Fung T. L. D., Delko T., Nicolas Lopez T., De Campos T., Calderon Duque T., Perra T., Liakakos T., Daskalakis T., Koeter T., Zalla T., Gonzalez T. E., Campagnaro T., Oumar T. A., Grossi U., Sosa V., Testa V., Tomajer V., Andriola V., Tonini V., Celentano V., Voglino V., Katta V. R., Garcia Orozco V. H., Turrado-Rodriguez V., Visag-Castillo V., Graham V., Rachkov V., Papagni V., Vigorita V., Jimenez Carneros V., Bellato V., Bechstein W., Altinel Y., and Balciscueta Z.

Abstract

Background: In 2020, ACIE Appy study showed that COVID-19 pandemic heavily affected the management of patients with acute appendicitis (AA) worldwide, with an increased rate of non-operative management (NOM) strategies and a trend toward open surgery due to concern of virus transmission by laparoscopy and controversial recommendations on this issue. The aim of this study was to survey again the same group of surgeons to assess if any difference in management attitudes of AA had occurred in the later stages of the outbreak. Methods: From August 15 to September 30, 2021, an online questionnaire was sent to all 709 participants of the ACIE Appy study. The questionnaire included questions on personal protective equipment (PPE), local policies and screening for SARS-CoV-2 infection, NOM, surgical approach and disease presentations in 2021. The results were compared with the results from the previous study. Results: A total of 476 answers were collected (response rate 67.1%). Screening policies were significatively improved with most patients screened regardless of symptoms (89.5% vs. 37.4%) with PCR and antigenic test as the preferred test (74.1% vs. 26.3%). More patients tested positive before surgery and commercial systems were the preferred ones to filter smoke plumes during laparoscopy. Laparoscopic appendicectomy was the first option in the treatment of AA, with a declined use of NOM. Conclusion: Management of AA has improved in the last waves of pandemic. Increased evidence regarding SARS-COV-2 infection along with a timely healthcare systems response has been translated into tailored attitudes and a better care for patients with AA worldwide.

Published
2022

4. Correction: Evolving Trends in the Management of Acute Appendicitis During COVID-19 Waves: The ACIE Appy II Study (World Journal of Surgery, (2022), 46, 9, (2021-2035), 10.1007/s00268-022-06649-z)

Author

Pata F., Pata, F, Di Martino, M, Podda, M, Di Saverio, S, Ielpo, B, Pellino, G, Julio, A, Alshamrani, A, Alturkistani, A, Alghamdi, A, Almalki, A, Orengia, A, Kuvvetli, A, Pisanu, A, Smith, A, Trevino Figueroa, A, Nacion, A, Alhazmi, A, Bouhuwaish, A, Khalid, A, Alsufyani, A, Rubio, A, Bavikatte, A, Kumar, A, Jamiri, A, de San Ildefonso Pereira, A, Porcu, A, Sartori, A, Rocca, A, Sretenovic, A, Anselmo, A, De Luca, A, Charalabopoulos, A, Tzivanakis, A, Bandin, A, Najar, A, Frontali, A, Faisal, A, Roldan, A, Hamid, A, Andre, A, Minaya-Bravo, A, Das, A, Bondurri, A, Costanzi, A, Lucchi, A, Mihailescu, A, Police, A, Zuchini, A, Romano, A, Iossa, A, Chessa, A, Tromba, A, Castaldi, A, Brillantino, A, Ferronetti, A, Giuliani, A, Ramos-De la Medina, A, Tarasconi, A, Picciariello, A, Ioannidis, A, Leppaniemi, A, Rashid, A, Mitul, A, Mehraj, A, Laharwal, A, Iqbal, A, Liarakos, A, Marinis, A, de Andres-Asenjo, B, Matias-Garcia, B, De Simone, B, Creavin, B, Stubbs, B, Goh, B, Jovanovic, B, Sensi, B, Gazia, C, Cerdan, C, Diaz, C, Chacon, C, Yanez, C, Faro, C, Reinke, C, Dominguez, C, Paranjape, C, Thomas, C, Fung, C, De Lucia, C, Jennifer, C, Ovalle-Chao, C, Guerci, C, Kenington, C, Gica, C, Folliero, C, Varela, C, Popowich, D, Delogu, D, Zigiotto, D, Vinci, D, D'Antonio, D, Merlini, D, Moro-Valdezate, D, Keller, D, Nicolaescu, D, Sasia, D, Rodas, E, Linardoutsos, D, Russello, D, Najar-Castaneda, P, Stavrou, H, Rosso, E, Saladino, E, Ricciardi, E, Smith-Singares, E, Baili, E, Douka, E, Guaitoli, E, Francone, E, Vaterlini, E, Pierobon, E, Morales, E, Ros, E, Benzoni, E, Erdas, E, Pinotti, E, Colas-Ruiz, E, Laterza, E, Foianini, E, Cardamone, E, Licardie, E, Marino, F, Alsofyani, F, Qahtani, F, Khan, F, Maraska, F, Saliu, F, Madrid, F, Rosa, F, Luvisetto, F, Alconchel, F, Pareja-Ciuro, F, Neves, F, Agresta, F, Cordera, F, Pardo, F, Mendoza-Moreno, F, Munoz-Flores, F, Silvestri, F, Tropeano, F, Pecchini, F, Serio, F, Colombo, F, Di Marzo, F, Ferrara, F, Lancellotti, F, Litta, F, Martini, F, Roscio, F, Blanco-Antona, F, Barcenas, F, Schlottmann, F, Herrera-Almario, G, van Ramshorst, G, Gallo, G, Luglio, G, Kampouroglou, G, Papadopoulos, G, Arredondo, G, Calini, G, Formisano, G, Galiffa, G, Palini, G, Colucci, G, Pagano, G, Vanni, G, Pattacini, G, Gravante, G, Lisi, G, Bellanova, G, De Nobili, G, Necchi, G, Sinibaldi, G, Bacchiocchi, G, Bagaglini, G, Maggi, G, Izzo, G, Argenio, G, Brisinda, G, Esposito, G, Frazzetta, G, De Luca, G, Nigri, G, Sica, G, Martin-Martin, G, Ugon, G, Martinez-Mier, G, Machain Vega, G, Nari, G, Nikaj, H, Neri, I, San Roman, I, Fidoshev, I, Martinez, I, Negoi, I, Ortega, I, Vicente Rodriguez, I, Cornejo, I, Mora-Guzman, I, al-Najami, I, Romic, I, Balciscueta, I, Olivier, J, Lammel-Lindemann, J, Dziakova, J, Salinas, J, Jovanovic, J, Reyes, J, Salas, J, Diaz-Elizondo, J, Parreira, J, Bellido, J, Salamea, J, Martin del Olmo, J, Ordonez, J, Junaid, S, Davies, J, Sahnan, K, Bekele, K, Voon, K, Siragusa, L, Petagna, L, Ferrario, L, Giordano, L, Nespoli, L, Pio, L, Moletta, L, Curella, L, Taglietti, L, Bonavina, L, Conti, L, Perez-Sanchez, L, Cabrera Vargas, L, Sanchez-Guillen, L, Tallon-Aguilar, L, Khan, M, Spampinato, M, Viola, M, Malet, M, Angrisani, M, Calussi, M, Catarci, M, Giordano, M, Materazzo, M, Milone, M, Pellicciaro, M, Marino, M, Moreno Villamizar, M, Lolli, M, Bellini, M, Lemma, M, Chiarello, M, Montes-Manrique, M, Rodriguez-Lopez, M, Serradilla-Martin, M, Peter, M, Paniagua-Garcia-Senorans, M, Rutegard, M, Salo, M, Silveri, M, Veroux, M, Nardi, M, Rottoli, M, Tolonen, M, Pedraza Ciro, M, Zuluaga, M, Iacobone, M, Montuori, M, Ali, M, Garcia Dominguez, M, Paola, M, Piccoli, M, Campanelli, M, De Rosa, M, Manigrasso, M, Maruccia, M, Torre, M, Zuolo, M, Pera, M, Weerasekera, M, Prieto, M, Thway, M, Shaat, M, Azfar, M, Shalaby, M, Raza, M, Younis, M, Elhadi, M, Althomali, M, Al Amri, N, Dudi-Venkata, N, Alselaim, N, Smart, N, Trelles, N, Falco, N, Petrucciani, N, Antonacci, N, Cillara, N, Gica, N, Pecorelli, N, Tamini, N, Machairas, N, Feituri, N, Ortega Torrecilla, N, Avila Mercado, O, Alaamer, O, Irkorucu, O, Alsherif, O, Buonomo, O, Valles-Guerra, O, Ioannidis, O, Hernandez Palmas, O, Sanz Guadarrama, O, Bozbiyik, O, Rodrigues, P, Milito, P, Panaccio, P, Dorovinis, P, Prieto, P, Baroffio, P, Marsanic, P, Ajawin, P, Koh, P, Anoldo, P, Major, P, Alharthi, Q, Lui, R, Caruso, R, Brady, R, Rattan, R, Singhal, R, Angelico, R, Isernia, R, Tutino, R, Peltrini, R, Tejos, R, Fajardo, R, Elia, R, Morales-Conde, S, Benli, S, Fuentes, S, de las Casas, S, de Guzman Aragon, S, Vertaldi, S, Awad, S, Gentilli, S, Weckmann Lujan, S, Tayar, S, Althobaiti, S, Di Giovanni, S, Ghedan, S, Perez-Bertolez, S, Chiappetta, S, Delis, S, Scaringi, S, Cetinkunar, S, Kykalos, S, Muhammad Ali, S, Krivan, S, Fung, T, Delko, T, Nicolas Lopez, T, De Campos, T, Calderon Duque, T, Perra, T, Liakakos, T, Daskalakis, T, Koeter, T, Zalla, T, Gonzalez, T, Campagnaro, T, Oumar, T, Grossi, U, Sosa, V, Testa, V, Tomajer, V, Andriola, V, Tonini, V, Celentano, V, Voglino, V, Katta, V, Garcia Orozco, V, Turrado-Rodriguez, V, Visag-Castillo, V, Graham, V, Rachkov, V, Papagni, V, Vigorita, V, Jimenez Carneros, V, Bellato, V, Bechstein, W, Altinel, Y, Balciscueta, Z, Pata F., Di Martino M., Podda M., Di Saverio S., Ielpo B., Pellino G., Julio A., Alshamrani A., Alturkistani A., Alghamdi A., Almalki A., Orengia A., Kuvvetli A., Pisanu A., Smith A., Trevino Figueroa A. M., Nacion A. J., Alhazmi A., Bouhuwaish A., Khalid A., Alsufyani A., Rubio A. V., Bavikatte A., Kumar A., Jamiri A. -R., de San Ildefonso Pereira A., Porcu A., Sartori A., Rocca A., Sretenovic A., Anselmo A., De Luca A., Charalabopoulos A., Tzivanakis A., Bandin A., Najar A., Frontali A., Faisal A., Roldan A. M., Hamid A., Andre A., Minaya-Bravo A., Das A., Bondurri A., Costanzi A., Lucchi A., Mihailescu A., Police A., Zuchini A. M., Romano A., Iossa A., Chessa A., Tromba A., Castaldi A., Brillantino A., Ferronetti A., Giuliani A., Ramos-De la Medina A., Tarasconi A., Picciariello A., Ioannidis A., Leppaniemi A., Rashid A., Mitul A. R., Mehraj A., laharwal A., Iqbal A., Liarakos A., Marinis A., de Andres-Asenjo B., Matias-Garcia B., De Simone B., Creavin B., Stubbs B., Goh B., Jovanovic B., Sensi B., Gazia C., Cerdan C., Diaz C. J. G., Chacon C. P., Yanez C., Faro C. L., Reinke C., Dominguez C., Paranjape C., Thomas C., Fung C. C., De Lucia C., Jennifer C. H. F., Ovalle-Chao C., Guerci C., Kenington C., Gica C., Folliero C., Varela C., Popowich D., Delogu D., Zigiotto D., Vinci D., D'Antonio D., Merlini D. A., Merlini D., Moro-Valdezate D., Keller D., Nicolaescu D. C., Sasia D., Rodas E., Linardoutsos D., Russello D., Najar-Castaneda P. A., Stavrou H. G., Rosso E., Saladino E., Ricciardi E., Smith-Singares E., Baili E., Douka E., Guaitoli E., Francone E., Vaterlini E. M., Pierobon E. S., Morales E., Ros E. P., Benzoni E., Erdas E., Pinotti E., Colas-Ruiz E., Laterza E., Foianini E., Cardamone E., Licardie E., Marino F., Alsofyani F., Qahtani F., Khan F., Maraska F., Saliu F., Madrid F., Rosa F., Luvisetto F., Alconchel F., Pareja-Ciuro F., Neves F., Agresta F., Cordera F., Pardo F., Mendoza-Moreno F., Munoz-Flores F., Silvestri F. M., Tropeano F. P., Pecchini F., Serio F., Colombo F., Di Marzo F., Ferrara F., Lancellotti F., Litta F., Martini F., Roscio F., Blanco-Antona F., Barcenas F. J. Q., Schlottmann F., Herrera-Almario G., van Ramshorst G., Gallo G., Luglio G., Kampouroglou G., Papadopoulos G., Arredondo G., Calini G., Formisano G., Galiffa G., Palini G. M., Colucci G., Pagano G., Vanni G., Pattacini G. C., Gravante G., Lisi G., Bellanova G., De Nobili G., Necchi G. S., Sinibaldi G., Bacchiocchi G., Bagaglini G., Maggi G., Izzo G., Argenio G., Brisinda G., Esposito G., Frazzetta G., De Luca G. M., Nigri G., Sica G., Martin-Martin G., Ugon G. A., Martinez-Mier G., Machain Vega G. M., Nari G., Nikaj H., Neri I., San Roman I. A., Fidoshev I., Martinez I., Negoi I., Ortega I., Vicente Rodriguez I., Cornejo I., Mora-Guzman I., al-Najami I., Romic I., Balciscueta I., Olivier J., Lammel-Lindemann J., Dziakova J., Salinas J., Jovanovic J. P., Reyes J. A. S., Salas J., Diaz-Elizondo J. A., Parreira J. G., Bellido J., Salamea J., Martin del Olmo J. C., Ordonez J. M., Junaid S., Davies J., Sahnan K., Bekele K., Voon K., Siragusa L., Petagna L., Ferrario L., Giordano L., Nespoli L., Pio L., Moletta L., Curella L., Taglietti L., Bonavina L., Conti L., Perez-Sanchez L. E., Cabrera Vargas L. F., Sanchez-Guillen L., Tallon-Aguilar L., Khan M., Spampinato M. G., Viola M., Malet M. V., Angrisani M., Calussi M., Catarci M., Giordano M., Materazzo M., Milone M., Pellicciaro M., Marino M. V., Moreno Villamizar M. D., Lolli M. G., Bellini M. I., Lemma M., Chiarello M. M., Montes-Manrique M., Rodriguez-Lopez M., Serradilla-Martin M., Peter M., Paniagua-Garcia-Senorans M., Rutegard M., Salo M., Silveri M., Veroux M., Nardi M., Rottoli M., Tolonen M., Pedraza Ciro M., Zuluaga M., Iacobone M., Montuori M., Ali M., Garcia Dominguez M., Paola M. M., Piccoli M., Campanelli M., De Rosa M., Manigrasso M., Maruccia M., Torre M., Zuolo M., Pera M., Weerasekera M., Prieto M., Thway M. M., Shaat M., Azfar M., Shalaby M., Raza M. A., Younis M. U., Elhadi M., AlThomali M., Al Amri N., Dudi-Venkata N., Alselaim N., Smart N., Trelles N., Falco N., Petrucciani N., Antonacci N., Cillara N., Gica N., Pecorelli N., Tamini N., Machairas N., Feituri N., Ortega Torrecilla N., Avila Mercado O., AlAamer O., Irkorucu O., Alsherif O., Buonomo O. C., Valles-Guerra O., Ioannidis O., Hernandez Palmas O. I., Sanz Guadarrama O., Bozbiyik O., Rodrigues P., Milito P., Panaccio P., Dorovinis P., Prieto P., Baroffio P., Marsanic P., Ajawin P., Koh P. S., Anoldo P., Major P., Alharthi Q., Lui R., Caruso R., Brady R., Rattan R., Singhal R., Angelico R., Isernia R. M., Tutino R., Peltrini R., Tejos R., Fajardo R., Elia R., Morales-Conde S., Benli S., Fuentes S., de las Casas S. G., de Guzman Aragon S. O., Vertaldi S., Awad S., Gentilli S., Weckmann Lujan S. A., Tayar S., Althobaiti S., Di Giovanni S., Ghedan S., Perez-Bertolez S., Chiappetta S., Delis S., Scaringi S., Cetinkunar S., Kykalos S., Muhammad Ali S., Krivan S., Fung T. L. D., Delko T., Nicolas Lopez T., De Campos T., Calderon Duque T., Perra T., Liakakos T., Daskalakis T., Koeter T., Zalla T., Gonzalez T. E., Campagnaro T., Oumar T. A., Grossi U., Sosa V., Testa V., Tomajer V., Andriola V., Tonini V., Celentano V., Voglino V., Katta V. R., Garcia Orozco V. H., Turrado-Rodriguez V., Visag-Castillo V., Graham V., Rachkov V., Papagni V., Vigorita V., Jimenez Carneros V., Bellato V., Bechstein W., Altinel Y., Balciscueta Z., Pata F., Pata, F, Di Martino, M, Podda, M, Di Saverio, S, Ielpo, B, Pellino, G, Julio, A, Alshamrani, A, Alturkistani, A, Alghamdi, A, Almalki, A, Orengia, A, Kuvvetli, A, Pisanu, A, Smith, A, Trevino Figueroa, A, Nacion, A, Alhazmi, A, Bouhuwaish, A, Khalid, A, Alsufyani, A, Rubio, A, Bavikatte, A, Kumar, A, Jamiri, A, de San Ildefonso Pereira, A, Porcu, A, Sartori, A, Rocca, A, Sretenovic, A, Anselmo, A, De Luca, A, Charalabopoulos, A, Tzivanakis, A, Bandin, A, Najar, A, Frontali, A, Faisal, A, Roldan, A, Hamid, A, Andre, A, Minaya-Bravo, A, Das, A, Bondurri, A, Costanzi, A, Lucchi, A, Mihailescu, A, Police, A, Zuchini, A, Romano, A, Iossa, A, Chessa, A, Tromba, A, Castaldi, A, Brillantino, A, Ferronetti, A, Giuliani, A, Ramos-De la Medina, A, Tarasconi, A, Picciariello, A, Ioannidis, A, Leppaniemi, A, Rashid, A, Mitul, A, Mehraj, A, Laharwal, A, Iqbal, A, Liarakos, A, Marinis, A, de Andres-Asenjo, B, Matias-Garcia, B, De Simone, B, Creavin, B, Stubbs, B, Goh, B, Jovanovic, B, Sensi, B, Gazia, C, Cerdan, C, Diaz, C, Chacon, C, Yanez, C, Faro, C, Reinke, C, Dominguez, C, Paranjape, C, Thomas, C, Fung, C, De Lucia, C, Jennifer, C, Ovalle-Chao, C, Guerci, C, Kenington, C, Gica, C, Folliero, C, Varela, C, Popowich, D, Delogu, D, Zigiotto, D, Vinci, D, D'Antonio, D, Merlini, D, Moro-Valdezate, D, Keller, D, Nicolaescu, D, Sasia, D, Rodas, E, Linardoutsos, D, Russello, D, Najar-Castaneda, P, Stavrou, H, Rosso, E, Saladino, E, Ricciardi, E, Smith-Singares, E, Baili, E, Douka, E, Guaitoli, E, Francone, E, Vaterlini, E, Pierobon, E, Morales, E, Ros, E, Benzoni, E, Erdas, E, Pinotti, E, Colas-Ruiz, E, Laterza, E, Foianini, E, Cardamone, E, Licardie, E, Marino, F, Alsofyani, F, Qahtani, F, Khan, F, Maraska, F, Saliu, F, Madrid, F, Rosa, F, Luvisetto, F, Alconchel, F, Pareja-Ciuro, F, Neves, F, Agresta, F, 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M., Nacion A. J., Alhazmi A., Bouhuwaish A., Khalid A., Alsufyani A., Rubio A. V., Bavikatte A., Kumar A., Jamiri A. -R., de San Ildefonso Pereira A., Porcu A., Sartori A., Rocca A., Sretenovic A., Anselmo A., De Luca A., Charalabopoulos A., Tzivanakis A., Bandin A., Najar A., Frontali A., Faisal A., Roldan A. M., Hamid A., Andre A., Minaya-Bravo A., Das A., Bondurri A., Costanzi A., Lucchi A., Mihailescu A., Police A., Zuchini A. M., Romano A., Iossa A., Chessa A., Tromba A., Castaldi A., Brillantino A., Ferronetti A., Giuliani A., Ramos-De la Medina A., Tarasconi A., Picciariello A., Ioannidis A., Leppaniemi A., Rashid A., Mitul A. R., Mehraj A., laharwal A., Iqbal A., Liarakos A., Marinis A., de Andres-Asenjo B., Matias-Garcia B., De Simone B., Creavin B., Stubbs B., Goh B., Jovanovic B., Sensi B., Gazia C., Cerdan C., Diaz C. J. G., Chacon C. P., Yanez C., Faro C. L., Reinke C., Dominguez C., Paranjape C., Thomas C., Fung C. C., De Lucia C., Jennifer C. H. 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U., Elhadi M., AlThomali M., Al Amri N., Dudi-Venkata N., Alselaim N., Smart N., Trelles N., Falco N., Petrucciani N., Antonacci N., Cillara N., Gica N., Pecorelli N., Tamini N., Machairas N., Feituri N., Ortega Torrecilla N., Avila Mercado O., AlAamer O., Irkorucu O., Alsherif O., Buonomo O. C., Valles-Guerra O., Ioannidis O., Hernandez Palmas O. I., Sanz Guadarrama O., Bozbiyik O., Rodrigues P., Milito P., Panaccio P., Dorovinis P., Prieto P., Baroffio P., Marsanic P., Ajawin P., Koh P. S., Anoldo P., Major P., Alharthi Q., Lui R., Caruso R., Brady R., Rattan R., Singhal R., Angelico R., Isernia R. M., Tutino R., Peltrini R., Tejos R., Fajardo R., Elia R., Morales-Conde S., Benli S., Fuentes S., de las Casas S. G., de Guzman Aragon S. O., Vertaldi S., Awad S., Gentilli S., Weckmann Lujan S. A., Tayar S., Althobaiti S., Di Giovanni S., Ghedan S., Perez-Bertolez S., Chiappetta S., Delis S., Scaringi S., Cetinkunar S., Kykalos S., Muhammad Ali S., Krivan S., Fung T. L. D., Delko T., Nicolas Lopez T., De Campos T., Calderon Duque T., Perra T., Liakakos T., Daskalakis T., Koeter T., Zalla T., Gonzalez T. E., Campagnaro T., Oumar T. A., Grossi U., Sosa V., Testa V., Tomajer V., Andriola V., Tonini V., Celentano V., Voglino V., Katta V. R., Garcia Orozco V. H., Turrado-Rodriguez V., Visag-Castillo V., Graham V., Rachkov V., Papagni V., Vigorita V., Jimenez Carneros V., Bellato V., Bechstein W., Altinel Y., and Balciscueta Z.

Abstract

In the original online version of this article Oreste Claudio Buonomo’s family name was misspelled. The original article was corrected.

Published
2022

6. Integrating radiology vertically into an undergraduate medical education curriculum: a triphasic integration approach

Author

Al Qahtani F and Abdelaziz A

Subjects
Special aspects of education, LC8-6691, Medicine (General), R5-920
Abstract

Fahd Al Qahtani,1 Adel Abdelaziz2,31Radiology Department, Faculty of Medicine, Al-Baha University, Al-Baha, Saudi Arabia; 2Medical Education Development Unit, Faculty of Medicine, Al-Baha University, Al-Baha, Saudi Arabia; 3Medical Education Department, Faculty of Medicine, Suez Canal University, Ismailia, EgyptAbstract: Fulfilling the goal of integrating radiology into undergraduate medical curricula is a real challenge due to the enduring faith assuming that traditional medical disciplines are worthy of consuming the available study time. In this manner, radiology is addressed occasionally and with relevance to these traditional disciplines. In Al-Baha University Faculty of Medicine, Al-Baha, Saudi Arabia, efforts have been made to integrate radiology vertically and in a structured manner into the undergraduate curriculum from the first year to the sixth year. For achieving convenient integration of radiology, a triphasic approach to integration is adopted. This approach consists of the integration of radiology foundations into the basic sciences phase, development of a distinct 4-week module in year 4, and finally, integration of clinical applications of radiology in the clinical phase modules. Feedback of students and inferences obtained through assessment and program evaluation are in favor of this approach to integration. Minor reform and some improvement related to time allocated and content balancing are still indicated.Keywords: radiology foundations, radiology module, students assessment

Published
2014

16. Evolving Trends in the Management of Acute Appendicitis During COVID-19 Waves: The ACIE Appy II Study

Author

Pata, Francesco, Di Martino, Marcello, Podda, Mauro, Di Saverio, Salomone, Ielpo, Benedetto, Pellino, Gianluca, Julio, Abba, Alshamrani, Abdullah, Alturkistani, Abdullah, Alghamdi, Abdulrahman, Almalki, Abdulrahman, Orengia, Adam, Kuvvetli, Adnan, Pisanu, Adolfo, Smith, Adrian, Treviño Figueroa, Adriana Michelle, Nacion, Aeris Jane, Alhazmi, Ahmad, Bouhuwaish, Ahmad, Khalid, Ahmad, Alsufyani, Ahmed, Rubio, Ainhoa Valle, Bavikatte, Akshay, Kumar, Akshay, Jamiri, Al-Radjid, de San Ildefonso Pereira, Alberto, Porcu, Alberto, Sartori, Alberto, Rocca, Aldo, Sretenovic, Aleksandar, Anselmo, Alessandro, De Luca, Alessandro, Charalabopoulos, Alexandros, Tzivanakis, Alexios, Bandin, Alfonso, Nájar, Alfonso, Frontali, Alice, Faisal, Alsulaimani, Roldan, Amaia Martínez, Hamid, Amal, André, Ana, Minaya-Bravo, Ana, Das, Andre, Bondurri, Andrea, Costanzi, Andrea, Lucchi, Andrea, Mihailescu, Andrei, Police, Andrea, Zuchini, Andres Mendoza, Romano, Angela, Iossa, Angelo, Chessa, Antonella, Tromba, Antonella, Castaldi, Antonio, Brillantino, Antonio, Ferronetti, Antonio, Giuliani, Antonio, Ramos-De la Medina, Antonio, Tarasconi, Antonio, Picciariello, Arcangelo, Ioannidis, Argyrios, Leppäniemi, Ari, Rashid, Arshad, Mitul, Ashrarur Rahman, Mehraj, Asif, Laharwal, Asim, Iqbal, Atif, Liarakos, Athanasios, Marinis, Athanasios, de Andrés-Asenjo, Beatriz, Matías-García, Belén, De Simone, Belinda, Creavin, Ben, Stubbs, Ben, Goh, Brian, Jovanovic, Branislav, Sensi, Bruno, Gazia, Carlo, Cerdán, Carlos, Díaz, Carlos Javier Gómez, Chacón, Carlos Petrola, Yánez, Carlos, Faro, Carmelo Lo, Reinke, Caroline, Dominguez, Casandra, Paranjape, Charudutt, Thomas, Charlotte, Fung, Chia Chi, De Lucia, Chiara, Jennifer, Chiu Hiu Fung, Ovalle-Chao, Christian, Guerci, Claudio, Kenington, Cleo, Gica, Corina, Folliero, Cristina, Varela, Cristopher, Popowich, Daniel, Delogu, Daniele, Zigiotto, Daniele, Vinci, Danilo, D’Antonio, Dario, Merlini, David Alessio, Merlini, David, Moro-Valdezate, David, Keller, Deborah, Nicolaescu, Diana Cristiana, Sasia, Diego, Rodas, Edgar, Linardoutsos, Dimitrios, Russello, Domenico, Nájar-Castañeda, Pedro Alfonso, Stavrou, Habil Gregor, Rosso, Edoardo, Saladino, Edoardo, Ricciardi, Edoardo, Smith-Singares, Eduardo, Baili, Efstratia, Douka, Eleftheria, Guaitoli, Eleonora, Francone, Elisa, Vaterlini, Elisa Maria, Pierobon, Elisa Sefora, Morales, Emilio, Ros, Emilio Peña, Benzoni, Enrico, Erdas, Enrico, Pinotti, Enrico, Colás-Ruiz, Enrique, Laterza, Ernesto, Foianini, Esteban, Cardamone, Eugenia, Licardie, Eugenio, Marino, Fabio, Alsofyani, Fahad, Qahtani, Fahad, Khan, Farhan, Maraska, Fatlum, Saliu, Fatmir, Madrid, Fausto, Rosa, Fausto, Luvisetto, Federico, Alconchel, Felipe, Pareja-Ciuro, Felipe, Neves, Fernanda, Agresta, Ferdinando, Cordera, Fernando, Pardo, Fernando, Mendoza-Moreno, Fernando, Munoz-Flores, Fernando, Silvestri, Francesca Maria, Tropeano, Francesca Paola, Pecchini, Francesca, Serio, Francesca, Colombo, Francesco, Di Marzo, Francesco, Ferrara, Francesco, Lancellotti, Francesco, Litta, Francesco, Martini, Francesco, Roscio, Francesco, Blanco-Antona, Francisco, Barcenas, Francisco Javier Quezada, Schlottmann, Francisco, Herrera-Almario, Gabriel, van Ramshorst, Gabrielle, Gallo, Gaetano, Luglio, Gaetano, Kampouroglou, Georgios, Papadopoulos, Georgios, Arredondo, Gerardo, Calini, Giacomo, Formisano, Giampaolo, Galiffa, Giampaolo, Palini, Gian Marco, Colucci, Gianluca, Pagano, Gianluca, Vanni, Gianluca, Pattacini, Gianmaria Casoni, Gravante, Gianpiero, Lisi, Giorgio, Bellanova, Giovanni, De Nobili, Giovanni, Necchi, Giovanni Sammy, Sinibaldi, Giovanni, Bacchiocchi, Giulia, Bagaglini, Giulia, Maggi, Giulia, Izzo, Giuliano, Argenio, Giulio, Brisinda, Giuseppe, Esposito, Giuseppe, Frazzetta, Giuseppe, De Luca, Giuseppe Massimiliano, Nigri, Giuseppe, Sica, Giuseppe, Martin-Martin, Gonzalo, Ugon, Gustavo Armand, Martinez-Mier, Gustavo, Machain Vega, Gustavo Miguel, Nari, Gustavo, Nikaj, Herald, Neri, Ignacio, San Roman, Igor Alberdi, Fidoshev, Iliya, Martínez, Iñaki, Negoi, Ionut, Ortega, Irene, Vicente Rodríguez, Irune, Cornejo, Isabel, Mora-Guzmán, Ismael, al-Najami, Issam, Romic, Ivan, Balciscueta, Izaskun, Olivier, James, Lammel-Lindemann, Jan, Dziakova, Jana, Salinas, Javier, Jovanovic, Jelena Pejanovic, Reyes, Jeryl Anne Silvia, Salas, Joanne, Diaz-Elizondo, Jose Antonio, Parreira, Jose Gustavo, Bellido, Juan, Salamea, Juan, Martín del Olmo, Juan Carlos, Ordoñez, Juliana María, Junaid, Sofi, Davies, Justin, Sahnan, Kapil, Bekele, Kebebe, Voon, Kelvin, Siragusa, Leandro, Petagna, Lorenzo, Ferrario, Luca, Giordano, Luca, Nespoli, Luca, Pio, Luca, Moletta, Lucia, Curella, Luciano, Taglietti, Lucio, Bonavina, Luigi, Conti, Luigi, Pérez-Sánchez, Luis Eduardo, Cabrera Vargas, Luis Felipe, Sánchez-Guillén, Luis, Tallon-Aguilar, Luis, Khan, Mansoor, Spampinato, Marcello Giuseppe, Viola, Marcelo, Malet, Marcelo Viola, Angrisani, Marco, Calussi, Marco, Catarci, Marco, Giordano, Marco, Materazzo, Marco, Milone, Marco, Pellicciaro, Marco, Marino, Marco Vito, Moreno Villamizar, María Daniela, Lolli, Maria Giulia, Bellini, Maria Irene, Lemma, Maria, Chiarello, Maria Michela, Montes-Manrique, Mario, Rodriguez-Lopez, Mario, Serradilla-Martín, Mario, Peter, Mark, Paniagua-García-Señoráns, Marta, Rutegård, Martin, Salö, Martin, Silveri, Massimiliano, Veroux, Massimiliano, Nardi, Matteo, Rottoli, Matteo, Tolonen, Matti, Pedraza Ciro, Mauricio, Zuluaga, Mauricio, Iacobone, Maurizio, Montuori, Mauro, Ali, Mazin, García Domínguez, Melody, Paola, Menna Maria, Piccoli, Micaela, Campanelli, Michela, De Rosa, Michele, Manigrasso, Michele, Maruccia, Michele, Torre, Michele, Zuolo, Michele, Pera, Miguel, Weerasekera, Mihiri, Prieto, Mikel, Thway, Min Myat, Shaat, Mohamed, Azfar, Mohammad, Shalaby, Mostafa, Raza, Muhammad Asif, Younis, Muhammad Umar, Elhadi, Muhammed, Ali, Mujahid, Althomali, Musab, Al Amri, Nadiah, Dudi-Venkata, Nagendra, Alselaim, Nahar, Smart, Neil, Trelles, Nelson, Falco, Nicolò, Petrucciani, Niccolo, Antonacci, Nicola, Cillara, Nicola, Gica, Nicolae, Pecorelli, Nicolò, Tamini, Nicolò, Machairas, Nikolaos, Feituri, Nura, Ortega Torrecilla, Nuria, Avila Mercado, Octavio, Alaamer, Ohood, Irkorucu, Oktay, Alsherif, Omar, Buonomi, Oreste Claudio, Valles-Guerra, Orestes, Ioannidis, Orestis, Hernández Palmas, Oscar Isaac, Sanz Guadarrama, Oscar, Bozbiyik, Osman, Rodrigues, Pablo, Milito, Pamela, Panaccio, Paolo, Dorovinis, Panagiotis, Prieto, Paola, Baroffio, Paolo, Marsanic, Patrizia, Ajawin, Pawel, Koh, Peng Soon, Anoldo, Pietro, Major, Piotr, Alharthi, Qasem, Lui, Rashid, Caruso, Riccardo, Brady, Richard, Rattan, Rishi, Singhal, Rishi, Angelico, Roberta, Isernia, Roberta Maria, Tutino, Roberta, Peltrini, Roberto, Tejos, Rodrigo, Fajardo, Roosevelt, Elia, Rossella, Morales-Conde, Salvador, Benli, Sami, Fuentes, Sara, de las Casas, Sara Gortázar, de Guzmán Aragón, Sara Ortiz, Vertaldi, Sara, Awad, Selmy, Gentilli, Sergio, Weckmann Lujan, Sergio Alberto, Tayar, Serkan, Althobaiti, Shabab, Di Giovanni, Silvia, Ghedan, Soliman, Pérez-Bertólez, Sonia, Chiappetta, Sonja, Delis, Spiros, Scaringi, Stefano, Çetinkünar, Süleyman, Kykalos, Stylianos, Muhammad Ali, Syed, Krivan, Sylvia, Fung, Tak Lit Derek, Delko, Tarik, Nicolás López, Tatiana, De Campos, Tercio, Calderón Duque, Teresa, Perra, Teresa, Liakakos, Theodore, Daskalakis, Theodoros, Koëter, Tijmen, Zalla, Tiku, González, Tomás Elosua, Campagnaro, Tommaso, Oumar, Toure Alpha, Grossi, Ugo, Sosa, Valentina, Testa, Valentina, Tomajer, Valentina, Andriola, Valeria, Tonini, Valeria, Celentano, Valerio, Voglino, Valerio, Katta, Venkateswara Rao, García Orozco, Víctor Hugo, Turrado-Rodriguez, Victor, Visag-Castillo, Victor, Graham, Victoria, Rachkov, Viktor, Papagni, Vincenzo, Vigorita, Vincenzo, Jiménez Carneros, Virginia, Bellato, Vittoria, Bechstein, Wolf, Altinel, Yuksel, Balciscueta, Zutoia, Pata, Francesco, Di Martino, Marcello, Podda, Mauro, Di Saverio, Salomone, Ielpo, Benedetto, Pellino, Gianluca, Luglio, Gaetano, Pata, F, Di Martino, M, Podda, M, Di Saverio, S, Ielpo, B, Pellino, G, Julio, A, Alshamrani, A, Alturkistani, A, Alghamdi, A, Almalki, A, Orengia, A, Kuvvetli, A, Pisanu, A, Smith, A, Trevino Figueroa, A, Nacion, A, Alhazmi, A, Bouhuwaish, A, Khalid, A, Alsufyani, A, Rubio, A, Bavikatte, A, Kumar, A, Jamiri, A, de San Ildefonso Pereira, A, Porcu, A, Sartori, A, Rocca, A, Sretenovic, A, Anselmo, A, De Luca, A, Charalabopoulos, A, Tzivanakis, A, Bandin, A, Najar, A, Frontali, A, Faisal, A, Roldan, A, Hamid, A, Andre, A, Minaya-Bravo, A, Das, A, Bondurri, A, Costanzi, A, Lucchi, A, Mihailescu, A, Police, A, Zuchini, A, Romano, A, Iossa, A, Chessa, A, Tromba, A, Castaldi, A, Brillantino, A, Ferronetti, A, Giuliani, A, Ramos-De la Medina, A, Tarasconi, A, Picciariello, A, Ioannidis, A, Leppaniemi, A, Rashid, A, Mitul, A, Mehraj, A, Laharwal, A, Iqbal, A, Liarakos, A, Marinis, A, de Andres-Asenjo, B, Matias-Garcia, B, De Simone, B, Creavin, B, Stubbs, B, Goh, B, Jovanovic, B, Sensi, B, Gazia, C, Cerdan, C, Diaz, C, Chacon, C, Yanez, C, Faro, C, Reinke, C, Dominguez, C, Paranjape, C, Thomas, C, Fung, C, De Lucia, C, Jennifer, C, Ovalle-Chao, C, Guerci, C, Kenington, C, Gica, C, Folliero, C, Varela, C, Popowich, D, Delogu, D, Zigiotto, D, Vinci, D, D'Antonio, D, Merlini, D, Moro-Valdezate, D, Keller, D, Nicolaescu, D, Sasia, D, Rodas, E, Linardoutsos, D, Russello, D, Najar-Castaneda, P, Stavrou, H, Rosso, E, Saladino, E, Ricciardi, E, Smith-Singares, E, Baili, E, Douka, E, Guaitoli, E, Francone, E, Vaterlini, E, Pierobon, E, Morales, E, Ros, E, Benzoni, E, Erdas, E, Pinotti, E, Colas-Ruiz, E, Laterza, E, Foianini, E, Cardamone, E, Licardie, E, Marino, F, Alsofyani, F, Qahtani, F, Khan, F, Maraska, F, Saliu, F, Madrid, F, Rosa, F, Luvisetto, F, Alconchel, F, Pareja-Ciuro, F, Neves, F, Agresta, F, Cordera, F, Pardo, F, Mendoza-Moreno, F, Munoz-Flores, F, Silvestri, F, Tropeano, F, Pecchini, F, Serio, F, Colombo, F, Di Marzo, F, Ferrara, F, Lancellotti, F, Litta, F, Martini, F, Roscio, F, Blanco-Antona, F, Barcenas, F, Schlottmann, F, Herrera-Almario, G, van Ramshorst, G, Gallo, G, Luglio, G, Kampouroglou, G, Papadopoulos, G, Arredondo, G, Calini, G, Formisano, G, Galiffa, G, Palini, G, Colucci, G, Pagano, G, Vanni, G, Pattacini, G, Gravante, G, Lisi, G, Bellanova, G, De Nobili, G, Necchi, G, Sinibaldi, G, Bacchiocchi, G, Bagaglini, G, Maggi, G, Izzo, G, Argenio, G, Brisinda, G, Esposito, G, Frazzetta, G, De Luca, G, Nigri, G, Sica, G, Martin-Martin, G, Ugon, G, Martinez-Mier, G, Machain Vega, G, Nari, G, Nikaj, H, Neri, I, San Roman, I, Fidoshev, I, Martinez, I, Negoi, I, Ortega, I, Vicente Rodriguez, I, Cornejo, I, Mora-Guzman, I, al-Najami, I, Romic, I, Balciscueta, I, Olivier, J, Lammel-Lindemann, J, Dziakova, J, Salinas, J, Jovanovic, J, Reyes, J, Salas, J, Diaz-Elizondo, J, Parreira, J, Bellido, J, Salamea, J, Martin del Olmo, J, Ordonez, J, Junaid, S, Davies, J, Sahnan, K, Bekele, K, Voon, K, Siragusa, L, Petagna, L, Ferrario, L, Giordano, L, Nespoli, L, Pio, L, Moletta, L, Curella, L, Taglietti, L, Bonavina, L, Conti, L, Perez-Sanchez, L, Cabrera Vargas, L, Sanchez-Guillen, L, Tallon-Aguilar, L, Khan, M, Spampinato, M, Viola, M, Malet, M, Angrisani, M, Calussi, M, Catarci, M, Giordano, M, Materazzo, M, Milone, M, Pellicciaro, M, Marino, M, Moreno Villamizar, M, Lolli, M, Bellini, M, Lemma, M, Chiarello, M, Montes-Manrique, M, Rodriguez-Lopez, M, Serradilla-Martin, M, Peter, M, Paniagua-Garcia-Senorans, M, Rutegard, M, Salo, M, Silveri, M, Veroux, M, Nardi, M, Rottoli, M, Tolonen, M, Pedraza Ciro, M, Zuluaga, M, Iacobone, M, Montuori, M, Ali, M, Garcia Dominguez, M, Paola, M, Piccoli, M, Campanelli, M, De Rosa, M, Manigrasso, M, Maruccia, M, Torre, M, Zuolo, M, Pera, M, Weerasekera, M, Prieto, M, Thway, M, Shaat, M, Azfar, M, Shalaby, M, Raza, M, Younis, M, Elhadi, M, Althomali, M, Al Amri, N, Dudi-Venkata, N, Alselaim, N, Smart, N, Trelles, N, Falco, N, Petrucciani, N, Antonacci, N, Cillara, N, Gica, N, Pecorelli, N, Tamini, N, Machairas, N, Feituri, N, Ortega Torrecilla, N, Avila Mercado, O, Alaamer, O, Irkorucu, O, Alsherif, O, Buonomi, O, Valles-Guerra, O, Ioannidis, O, Hernandez Palmas, O, Sanz Guadarrama, O, Bozbiyik, O, Rodrigues, P, Milito, P, Panaccio, P, Dorovinis, P, Prieto, P, Baroffio, P, Marsanic, P, Ajawin, P, Koh, P, Anoldo, P, Major, P, Alharthi, Q, Lui, R, Caruso, R, Brady, R, Rattan, R, Singhal, R, Angelico, R, Isernia, R, Tutino, R, Peltrini, R, Tejos, R, Fajardo, R, Elia, R, Morales-Conde, S, Benli, S, Fuentes, S, de las Casas, S, de Guzman Aragon, S, Vertaldi, S, Awad, S, Gentilli, S, Weckmann Lujan, S, Tayar, S, Althobaiti, S, Di Giovanni, S, Ghedan, S, Perez-Bertolez, S, Chiappetta, S, Delis, S, Scaringi, S, Cetinkunar, S, Kykalos, S, Muhammad Ali, S, Krivan, S, Fung, T, Delko, T, Nicolas Lopez, T, De Campos, T, Calderon Duque, T, Perra, T, Liakakos, T, Daskalakis, T, Koeter, T, Zalla, T, Gonzalez, T, Campagnaro, T, Oumar, T, Grossi, U, Sosa, V, Testa, V, Tomajer, V, Andriola, V, Tonini, V, Celentano, V, Voglino, V, Katta, V, Garcia Orozco, V, Turrado-Rodriguez, V, Visag-Castillo, V, Graham, V, Rachkov, V, Papagni, V, Vigorita, V, Jimenez Carneros, V, Bellato, V, Bechstein, W, Altinel, Y, Balciscueta, Z, Institut Català de la Salut, [Pata F] General Surgery Unit, UOC di Chirurgia, Nicola Giannettasio Hospital, CS, Italy. La Sapienza University, Rome, Italy. [Di Martino M] Division of Hepatobiliary and Liver Transplantation Surgery, A.O.R.N. Cardarelli, Naples, Italy. [Podda M] Department of Surgical Science, University of Cagliari, Cagliari, Italy. [Di Saverio S] Department of Surgery, Madonna del Soccorso General Hospital, San Benedetto del Tronto, Italy. [Ielpo B] Hepatobiliary division, Hospital del Mar, Universitat Pompeu Fabra, Barcelona, Spain. [Pellino G] Department of Advanced Medical and Surgical Sciences, Universitá degli Studi della Campania ‘‘Luigi Vanvitelli’’, Policlinico CS, Naples, Italy. Unitat de Cirurgia de Còlon i Recte, Vall d’Hebron Hospital Universitari, Barcelona, Spain, and Vall d'Hebron Barcelona Hospital Campus

Subjects
Investigative Techniques::Epidemiologic Methods::Data Collection::Surveys and Questionnaires [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], covid-19, surgery, coronavirus, sars-cov-2, appendicectomy, laparoscopy, nom, management, Enquestes, Apendicectomia, COVID-19 (Malaltia), surgery, Surgical Procedures, Operative::Digestive System Surgical Procedures::Appendectomy [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], Apendicitis, Pandèmia de COVID-19, 2020, Appendectomy, Humans, Appendiciti, Pandemics, Cirurgia, Pandemic, SARS-CoV-2, COVID-19, Digestive System Diseases::Gastrointestinal Diseases::Gastroenteritis::Digestive System Diseases::Gastrointestinal Diseases::Appendicitis [DISEASES], Otros calificadores::Otros calificadores::/cirugía [Otros calificadores], técnicas de investigación::métodos epidemiológicos::recopilación de datos::encuestas y cuestionarios [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], Appendicitis, Apendicitis - Cirurgia, Other subheadings::Other subheadings::/surgery [Other subheadings], Settore MED/18, Settore MED/18 - Chirurgia Generale, Acute Disease, enfermedades del sistema digestivo::enfermedades gastrointestinales::gastroenteritis::enfermedades del sistema digestivo::enfermedades gastrointestinales::apendicitis [ENFERMEDADES], intervenciones quirúrgicas::procedimientos quirúrgicos del sistema digestivo::apendicectomía [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], Human
Abstract

Background In 2020, ACIE Appy study showed that COVID-19 pandemic heavily affected the management of patients with acute appendicitis (AA) worldwide, with an increased rate of non-operative management (NOM) strategies and a trend toward open surgery due to concern of virus transmission by laparoscopy and controversial recommendations on this issue. The aim of this study was to survey again the same group of surgeons to assess if any difference in management attitudes of AA had occurred in the later stages of the outbreak. Methods From August 15 to September 30, 2021, an online questionnaire was sent to all 709 participants of the ACIE Appy study. The questionnaire included questions on personal protective equipment (PPE), local policies and screening for SARS-CoV-2 infection, NOM, surgical approach and disease presentations in 2021. The results were compared with the results from the previous study. Results A total of 476 answers were collected (response rate 67.1%). Screening policies were significatively improved with most patients screened regardless of symptoms (89.5% vs. 37.4%) with PCR and antigenic test as the preferred test (74.1% vs. 26.3%). More patients tested positive before surgery and commercial systems were the preferred ones to filter smoke plumes during laparoscopy. Laparoscopic appendicectomy was the first option in the treatment of AA, with a declined use of NOM. Conclusion Management of AA has improved in the last waves of pandemic. Increased evidence regarding SARS-COV-2 infection along with a timely healthcare systems response has been translated into tailored attitudes and a better care for patients with AA worldwide.

Published
2022

17. Patient's satisfaction with orthodontic treatment at King Khalid University, College Of Dentistry, Saudi Arabia.

Author

Shahrani, I., Tikare, S., Togoo, R. A., Qahtani, F., Assiri, K., and Meshari, A.

Subjects
*PATIENT satisfaction, *ORTHODONTICS, *DENTAL schools, *DENTIST-patient relationship
Abstract

Introduction: Patient satisfaction is important for ensuring patient's adherence in orthodontic treatment. As teaching institutions, dental college clinics must constantly strive to find a balance between satisfying the needs of the patients and ensuring proper training of the students. The objective of the present study was to assess dental patient's satisfaction with orthodontic treatment and related services at King Khalid University, College of Dentistry (KKU COD), Saudi Arabia. Materials and methods: A 19 item closed end questionnaire was developed and pretested to assess patient's satisfaction with orthodontic care. The questionnaire items were designed under three domains: 1) Reception and work environment, 2) doctor-patient relationship, and 3) treatment expectations and satisfaction. The study sample consisted of all patients consulting the orthodontic clinics during the time frame of the survey and those who were willing to participate. Results: A total of 72 patients completed the survey within the time framework. The mean age of the patients was 21.2 ± 8.06 of which males were 69.5% and Females 30.5%. The highest subscale score was found to be with patient's treatment expectations and satisfaction (92.6%) followed by reception and work environment (89.3%) and Dentist-patient relationship (82.7%). The overall patient's satisfaction for orthodontic services among the patients was found to be 87.1%. Conclusion: There was a high dental patient's satisfaction with orthodontic services at COD KKU, Saudi Arabia as a teaching institution. The dentist-relationship was found to be key factor in determining dental patient's satisfaction. [ABSTRACT FROM AUTHOR]

Published
2015
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18. Multicenter Experience for Early and Mid-Term Outcome of MyVal Transcatheter Pulmonary Valve Implantation.

Author

Al Nasef M, Erdem A, Aldudak B, Yildirim A, Hijazi ZM, Boudjemline Y, Al Riyami Z, Zunzunegui JL, Al Sahari A, Al Deham M, Meer Y, Al Alwi K, Al Saloos H, Abdulhamed J, AlShahrani D, Al Qahtani F, Al Tamimi O, Alissa M, Al Otay AM, and Momenah T

Subjects
Humans, Male, Child, Adolescent, Young Adult, Adult, Female, Treatment Outcome, Prosthesis Design, Cardiac Catheterization methods, Pulmonary Valve surgery, Heart Valve Prosthesis Implantation methods, Pulmonary Valve Insufficiency surgery, Pulmonary Valve Insufficiency etiology, Heart Valve Prosthesis
Abstract

Transcatheter pulmonary valve implantation (TPVI) is a surgical alternative for correcting dysfunctional right ventricular outflow tract in previously operated patients. MyVal transcatheter heart valve (THV) (Meril Life Sciences, India), a new transcatheter valve designed for aortic position has recently been reported to be implanted in pulmonary position. Myval transcatheter valve were implanted in patients with stenosed dysfunctional conduits, severe regurgitation from transannular patch or dysfunctional surgical pulmonary valves (Bioprosthesis). Procedural details and post-TPVI follow-up were analysed. Myval TPVI was used in Fifty three patients with median age of 15 years (IQR 12-19.5 years). Almost sixty percent of the patients were male, with a median weight of 50 kg (31-63 kg). Prestenting was used in more than 80 percent of patients (n = 45 patients), while 6 patients had a prior surgical valve implantation. After Myval TPVI implantation, the peak instantaneous gradient across the RVOT decreased from a median of 23.5 mmHg (IQR 10-53 mmHg) pre-procedure to 10 mmHg (IQR 5-16 mmHg) post-procedure. The median fluoroscopy time for the procedure was 35 min (IQR 23.5-44 min). The large sizes-mainly the 29-mm and 32 mm Myval (Navigator, Meril Life Sciences Pvt Ltd, India), were the most used size in 40% (n = 22) of the cases each. The median contrast volume used during the procedure was 247 mL (IQR 120-300 mL). Patients were followed for a median period of 360 days (IQR 164-525 days). At the last clinic follow-up, there was no tricuspid valve regurgitation. Moderate neo-pulmonary valve regurgitation was reported in three cases. Early experience of TPVI with MyVal is encouraging with procedural success in all patients and acceptable mid-term outcomes., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

Published
2024
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19. Traumatic brain injuries and maxillofacial fractures: a systematic review and meta-analysis.

Author

Othman A, Al-Mofreh Al-Qahtani F, Al-Qahtani H, Jaber M, Bishawi K, Hassan Khamis A, and Al-Shanably A

Subjects
Adult, Aged, Female, Humans, Male, Accidents, Traffic, Retrospective Studies, Brain Injuries, Traumatic diagnosis, Brain Injuries, Traumatic etiology, Maxillofacial Injuries diagnosis, Maxillofacial Injuries epidemiology, Maxillofacial Injuries surgery, Skull Fractures diagnosis, Skull Fractures etiology
Abstract

Traumatic brain injuries (TBIs) associated with maxillofacial fractures (MFFs) are a public health concern worldwide, especially among adult-aged males. There is an urgent need for early detection of associated TBIs in patients with MFFs during the initial assessment and treatment stage to reduce morbidity and mortality. The objective of the present study was to systematically review the literature to determine specific MFF situations associated with TBIs and to identify the factors associated with TBIs in patients with MFFs. The protocol was developed in accord with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols (PRISMA-P) and was registered to the International Prospective Register of Systematic Reviews (PROSPERO) under the registration number CRD42020155912. Overall, of 26,774 patients recorded, 13,667 patients (51.04%) sustained MFFs with an associated TBI. The male to female ratio was 4.8:1. RTA was the most common cause. The most common TBIs were concussions, contusions, and closed brain injuries. Within the limits of this study, it was concluded that TBI-related MFFs should be suspected whenever maxillary or mandibular bone fractures occur, especially among adults, males, and people with injuries caused by RTAs and assaults. There is a need to increase the awareness of maxillofacial surgeons on the possible associations of combined maxillofacial trauma and brain injuries., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

Published
2023
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20. Levels of whole salivary advanced glycation end products and interleukin-17 and peri-implant clinical and radiographic status in patients with osteoporosis at 6-years' follow-up.

Author

Al-Qahtani F, Alqhtani N, Divakar DD, Alkhtani F, and Alqarawi FK

Subjects
Humans, Interleukin-17, Glycation End Products, Advanced, Follow-Up Studies, Retrospective Studies, Alveolar Bone Loss diagnostic imaging, Dental Implants adverse effects, Osteoporosis
Abstract

Background: There are no studies that have assessed advanced glycation end products (AGEs) and interleukin 17A (IL-17A) levels in whole saliva (WS) of patients with dental implants. The aim was to compare levels of AGEs and IL-17A in WS and peri-implant clinical and radiographic status of patients with and without osteoporosis at 6-years' follow-up., Methods: Osteoporotic (Group-1) and systemically healthy controls (Group-2) having undergone dental implant therapy at least 5 years ago were included. A questionnaire was used to collect information about age, gender, duration and treatment of osteoporosis, number and duration of implants in function, and frequencies of toothbrushing, flossing and hygiene visits. Modified bleeding and plaque indies (mBI and mPI), peri-implant probing depth (PD) and crestal bone loss (CBL) were recorded. WS was collected and levels of AGEs and IL-17A were determined using enzyme linked immunosorbent assay. Sample-size estimation was done and statistical analyses were doing using the independent t- and Wilcoxon rank-sum tests. Statistical significance was marked for P-values that were below 0.01., Results: In patients with (n = 24) and without (n = 27) osteoporosis, implants were in function for 6.3 ± 0.27 and 6.6 ± 0.5 years, respectively. There was no significant difference in peri-implant mBI, PD, mPI and CBL in both groups. Levels of AGE in patients with (119.6 ± 26.5 μg/ml) and without (91.5 ± 14.6 μg/ml) osteoporosis were comparable. Levels of whole salivary IL-17A in patients without and with osteoporosis were 4.6 ± 0.3 and 5.1 ± 0.8 pg/ml, respectively. Flossing of full mouth interproximal spaces once and twice daily toothbrushing daily was reported by 100% patients with osteoporosis. Among patients with osteoporosis 75% and 25% individuals were receiving professional dental prophylaxis every 4 and 6 months, respectively., Conclusion: Within the limitations of the present study osteoporotic patients are not at an increased risk of peri-implant diseases and can demonstrate salivary AGE and IL-17A levels comparable to non-osteoporotic individuals as long as oral hygiene is stringently maintained., (© 2022. The Author(s).)

Published
2022
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21. Saudi Heart Association Guidelines on Best Practices in the Management of Chronic Coronary Syndromes.

Author

AlShammeri O, Al Saif S, Al Shehri H, Alasng M, Qaddoura F, Al Shehri M, Turkistani Y, Tash A, Alharbi W, Al Qahtani F, Diaz R, Mahaimeed W, Al Habeeb W, and Alfaraidy K

Abstract

Background: The prevalence of both chronic coronary syndrome (CCS) and its risk factors is alarming in Saudi Arabia and only a minority of patients achieve optimal medical management. Context-specific CCS guidelines outlining best clinical practices are therefore needed to address local gaps and challenges., Consensus Panel: A panel of experts representing the Saudi Heart Association (SHA) reviewed existing evidence and formulated guidance relevant to local clinical practice considering the characteristics of the Saudi population, the Saudi healthcare system, its resources and medical expertise. They were reviewed by external experts to ensure scientific and medical accuracy., Consensus Findings: Recommendations are provided on the clinical assessment and management of CCS, along with supporting evidence. Risk reduction through non-pharmacological therapy (lifestyle modifications) remains at the core of CCS management. Great emphasis should be placed on the use of available pharmacological options (anti-anginal therapy and event prevention) only as appropriate and necessary. Lifestyle counseling and pharmacological strategy must be optimized before considering revascularization, unless otherwise indicated. Revascularization strategies should be carefully considered by the Heart Team to ensure the appropriate choice is made in accordance to current guidelines and patient preference., Conclusion: Conscientious, multidisciplinary, and personalized clinical management is necessary to navigate the complex landscape of CCS in Saudi Arabia considering its population and resource differences. The reconciliation of international evidence and local characteristics is critical for the improvement of healthcare outcomes among CCS patients in Saudi Arabia., Competing Interests: Conflict of interest None declared., (© 2022 Saudi Heart Association.)

Published
2022
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22. Evaluation of pharmacy intern-led transition of care service at an academic hospital in Saudi Arabia: A prospective pilot study.

Author

Alghamdi A, Alhulaylah F, Al-Qahtani F, Alsallal D, Alshabanat N, Alanazi H, and Alshehri G

Abstract

Objectives: The transition of patients from one setting to another increases the risk of medication errors (MEs). This study aims to assess the implementation of pharmacy intern-led transition of care (TOC) service and to demonstrate its impact on the quality of patient care., Method: A prospective interventional pilot study was carried out from August 2020 to April 2021 at an academic hospital in Saudi Arabia. The TOC team consisted of three pharmacy interns and one pharmacist-in-charge. Daily activities included medication reconciliation, discharge counseling, and follow-up call after 3 days of discharge. The identified discrepancies were categorized according to the National Coordinating Council for Medication Error Reporting Program., Key Findings: A total of 182 patients were included in the analysis. During medication reconciliation, 102 discrepancies were detected, with an average of 0.7 discrepancy per patient. The most common discrepancy at admission and discharge was omission (41.7% and 70%, respectively). Category B was the most frequent and accounted for 46% at admission and 93% at discharge. Around 39% of TOC beneficiaries received a follow-up call, and all reported a high level of satisfaction with the service., Conclusion: Involving the pharmacy team in TOC activities was effective in identifying discrepancies and resolving MEs., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Disclosure. All authors have approved the final article and declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2022 The Authors.)

Published
2022
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23. Nontypical presentation of a common disease: a case report.

Author

Alshammasi W, Bargawi A, Abdulrahman A, Alhaji M, Al Qahtani F, and Aldajani A

Subjects
Aspirin therapeutic use, Child, Child, Preschool, Echocardiography, Female, Fever, Humans, Immunoglobulins, Intravenous, Mucocutaneous Lymph Node Syndrome complications, Mucocutaneous Lymph Node Syndrome diagnosis, Mucocutaneous Lymph Node Syndrome drug therapy
Abstract

Background: Kawasaki disease is an idiopathic medium-sized vasculitis that occurs primarily in infants and children younger than 5 years of age. Atypical Kawasaki disease applies to patients who do not fulfill the complete criteria of fever of 5 days or more with at least four of five features: bilateral conjunctival injection, changes in the lips and oral cavity, cervical lymphadenopathy, extremity changes, and polymorphous rash. Acute kidney injury is defined as a sudden decline in kidney function within hours, including structural injuries and loss of function. Acute kidney injury is extremely common in hospitalized pediatric patients. However, it is rarely documented in Kawasaki disease. Acute kidney injury is underestimated in Kawasaki disease due to the lack of a clear definition of age-specific normal serum creatinine levels and routine renal functions. This report describes a case who presented with clinical features suggestive of atypical Kawasaki disease and developed acute kidney injury., Case Presentation: A 2-year-old Saudi girl had a history of high-grade fever for 5 days, moderate dehydration, dry cracked lips, poor appetite, and generalized erythematous rash; therefore, she was diagnosed to have incomplete Kawasaki disease. Laboratory investigations revealed normochromic normocytic anemia, leukocytosis, thrombocytosis, high inflammatory markers, and acute kidney injury stage III. An echocardiogram showed a 4-mm dilatation on the left main coronary artery and a 3-mm dilatation on the right. A renal biopsy was not performed to identify the cause of the injury as it showed improvements after the start of the specific therapy for Kawasaki disease; intravenous immune globulin at a dose of 2 g/kg, aspirin at a high dosage of 80 mg/kg/day, and prednisolone at 2 mg/kg. In addition to the acute kidney injury management, normal saline boluses were followed by furosemide at a 2 mg/kg dose. Her urine output increased, and her renal functions normalized. She was discharged in good condition after 10 days., Conclusions: It is valuable to check renal function tests in a confirmed case of Kawasaki disease to reduce the negative consequences of late acute kidney injury discovery. Early detection and intervention make a substantial difference in acute kidney injury management., (© 2022. The Author(s).)

Published
2022
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25. Molecular insights into the coding region mutations of low-density lipoprotein receptor adaptor protein 1 (LDLRAP1) linked to familial hypercholesterolemia.

Author

Shaik NA, Al-Qahtani F, Nasser K, Jamil K, Alrayes NM, Elango R, Awan ZA, and Banaganapalli B

Subjects
Adaptor Proteins, Signal Transducing chemistry, Amino Acid Substitution, Computational Biology methods, Databases, Genetic, Genotype, Humans, Models, Molecular, Mutation, Missense, Phenotype, Protein Binding, ROC Curve, Structure-Activity Relationship, Adaptor Proteins, Signal Transducing genetics, Genetic Association Studies methods, Genetic Predisposition to Disease, Hyperlipoproteinemia Type II diagnosis, Hyperlipoproteinemia Type II genetics, Mutation, Open Reading Frames
Abstract

Background: Familial hypercholesterolemia (FH) is a lipid disorder caused by pathogenic mutations in LDLRAP1 gene. The present study has aimed to deepen our understanding about the pathogenicity predictions of FH causative genetic mutations, as well as their relationship to phenotype changes in LDLRAP1 protein, by utilizing multidirectional computational analysis., Methods: FH linked LDLRAP1 mutations were mined from databases, and the prediction ability of several pathogenicity classifiers against these clinical variants, was assessed through different statistical measures. Furthermore, these mutations were 3D modelled in protein structures to assess their impact on protein phenotype changes., Results: Our findings suggest that Polyphen-2, when compared with SIFT, M-CAP and CADD tools, can make better pathogenicity predictions for FH causative LDLRAP1 mutations. Through, 3D simulation and superimposition analysis of LDLRAP1 protein structures, it was found that missense mutations do not create any gross changes in the protein structure, although they could induce subtle structural changes at the level of amino acid residues. Near native molecular dynamic analysis revealed that missense mutations could induce variable degrees of fluctuation differences guiding the protein flexibility. Stability analysis showed that most missense mutations shifts the free energy equilibrium and hence they destabilize the protein. Molecular docking analysis demonstrates the molecular shifts in hydrogen and ionic bonds and Van der waals bonding properties, which further cause differences in the binding energy of LDLR-LDLRAP1 proteins., Conclusions: The diverse computational approaches used in the present study may provide a new dimension for exploring the structure-function relationship of the novel and deleterious LDLRAP1 mutations linked to FH., (© 2020 John Wiley & Sons, Ltd.)

Published
2020
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26. Facile spectroscopy and atomic force microscopy for the discrimination of α and β thalassemia traits and diseases: A photodiagnosis approach.

Author

AlZahrani KE, Devanesan S, Masilamani V, Al Qahtani F, AlSalhi MS, Canatan D, and Farhat K

Subjects
Adolescent, Adult, Child, Erythrocytes cytology, Female, Humans, Male, Young Adult, alpha-Thalassemia classification, beta-Thalassemia classification, Microscopy, Atomic Force methods, Spectrometry, Fluorescence methods, alpha-Thalassemia diagnostic imaging, beta-Thalassemia diagnostic imaging
Abstract

Thalassemia (Thal) is an inherited blood disorder endemic to the Mediterranean and Middle East (e.g., KSA and UAE). This disease is caused by defects in the synthesis of one or more hemoglobin chains in red blood cells (RBCs). Alpha (α) Thal is caused by a reduced or absent alpha globin segment. Similarly, beta (β) Thal is caused by a defect in the beta globin segment. We divided the diseases into four groups: α Thal trait, α Thal disease, β Thal trait, and β Thal disease. The α or β Thal traits are milder variants of these diseases and do not require treatment; but β Thal disease (and to a lesser extent, α Thal) causes hemolytic anemia, splenomegaly, and bone deformities and requires repeated lifelong blood transfusions. This paper presents results regarding the identification of Thal variants using fluorescence spectroscopy of blood biomolecules and atomic force microscopy analysis of the morphologic features of red blood cells. The combined results provide new insights into the characteristics of these diseases. Furthermore, this study shows why β Thal disease subjects are often transfusion-dependent, and α Thal disease subjects are only occasionally transfusion dependent., (Copyright © 2019 Elsevier B.V. All rights reserved.)

Published
2019
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27. Impact of Diabetes Mellitus on Human Erythrocytes: Atomic Force Microscopy and Spectral Investigations.

Author

S AlSalhi M, Devanesan S, E AlZahrani K, AlShebly M, Al-Qahtani F, Farhat K, and Masilamani V

Subjects
Adult, Erythrocytes metabolism, Female, Humans, Male, Microscopy, Atomic Force, Saudi Arabia, Spectrometry, Fluorescence, Young Adult, Diabetes Mellitus, Type 2 physiopathology, Erythrocytes pathology, Glycated Hemoglobin metabolism
Abstract

Diabetes mellitus (DM) is a common metabolic disease indicated by high sugar levels in the blood over a prolonged period. When left untreated, it can lead to long-term complications, such as cardiovascular disease, stroke, and diabetic retinopathy or foot ulcers. Approximately 415 million people (about 8.3% of the world's population) had diabetes worldwide in 2015, with 90% of the cases classified as Type 2 DM, which is caused by insulin resistance that arises mostly from being overweight and from a lack of exercise. DM affects every part of the body, including the erythrocytes. The aim of the present report is to gain insight into the damage done to the erythrocytes of patients classified with pre-diabetes and diabetes (plenty are found in the Kingdom of Saudi Arabia, a country where young people encompass a large segment of the population). The study presents results on the morphological analysis of erythrocytes by atomic force microscopy (AFM) and molecular investigations by fluorescence spectroscopy (FS). Our results indicate significant differences (in the morphology, size, and hemolytic end products) between the erythrocytes of diabetic patients (HbA1C, glycated hemoglobin, levels of 8⁻10%) and normal controls. It is well-known that DM and smoking are two major contributory factors for cardiovascular diseases (CVDs), and our observations presented in this study suggest that diabetes plays a relatively less damaging role than smoking for CVD.

Published
2018
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28. Brugada syndrome in a 4-year-old child with Lemierre syndrome-A case report.

Author

Alanazi S, Moafa H, Al-Qahtani F, and Hameed T

Abstract

Brugada syndrome is a rare arrhythmogenic disease with characteristic electrocardiogram (ECG) findings. Fever represents an important triggering factor. We report the case of a 4-year-old Saudi boy who was diagnosed with Lemierre syndrome and subsequently developed Brugada syndrome.

Published
2018
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29. Comparative Outcomes of Surgical and Transcatheter Aortic Valve Replacement for Aortic Stenosis in Nonagenarians.

Author

Zack CJ, Al-Qahtani F, Kawsara A, Al-Hijji M, Amin AH, and Alkhouli M

Subjects
Aged, 80 and over, Aortic Valve Stenosis mortality, Female, Hospital Mortality, Humans, Male, Treatment Outcome, United States epidemiology, Aortic Valve surgery, Aortic Valve Stenosis surgery, Heart Valve Prosthesis, Transcatheter Aortic Valve Replacement mortality
Abstract

Transcatheter aortic valve replacement (TAVR) emerged as a promising alternative to surgical aortic valve replacement (SAVR) in extreme-aged patients with severe aortic stenosis (AS). Data on the outcomes of TAVR or SAVR in nonagenarians are limited. The Nationwide Inpatient Sample was used to identify patients aged 90 years or older who underwent TAVR or SAVR from 2004 to 2013. In-hospital morbidity and mortality were assessed. From 2004 to 2013, 9,066 (national estimate) nonagenarians underwent aortic valve replacement. After the introduction of TAVR, most nonagenarians were treated with TAVR (76%) compared with SAVR (24%). A total of 1,847 nonagenarians who underwent SAVR (n = 1,152) or TAVR (n = 695) were included in the analysis. In-hospital mortality was similar between patients who underwent SAVR (6.4%) compared with TAVR (6.5%; p = 0.29). Vascular complications were more common after TAVR (11.9% vs 6.3%, p <0.001), whereas blood transfusion (46.2% vs 33.7%, p <0.001), and acute kidney injury (25.8% vs 20.4%, p = 0.009) were more common after SAVR. Pacemaker implantation and stroke rates were similar between the 2 groups. In a propensity-matched analysis of 630 patients who underwent isolated TAVR (n = 315) or SAVR (n = 315), in-hospital mortality was similar for (6.0% for SAVR vs 7.9% for TAVR, p = 0.35). SAVR was associated with higher rates of acute kidney injury (24.1% vs 16.8%, p = 0.02) and blood transfusion (46.0% vs 35.2%, p = 0.001), whereas TAVR was associated with increased rates of vascular complications (10.2% vs 6.0%, p = 0.07). Stroke (4.1% vs 4.1%, p = 0.99) and pacemaker implantation rates were also similar (13.0% vs 9.2%, p = 0.12) between the TAVR and SAVR groups, respectively. In conclusion, in nonagenarians, both SAVR and TAVR can be performed with acceptable in-hospital outcomes. Referral for aortic valve replacement in these patients should not be precluded based on age alone., (Copyright © 2016 Elsevier Inc. All rights reserved.)

Published
2017
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30. Granulomatous disease in a child treated with etanercept.

Author

Alhajri M, Aljumaah S, Aleyouni Y, Al-Qahtani F, Alhazzaa S, and Al-Mayouf SM

Subjects
Antirheumatic Agents therapeutic use, Child, Drug Therapy, Combination, Etanercept, Humans, Immunoglobulin G therapeutic use, Male, Methotrexate therapeutic use, Receptors, Tumor Necrosis Factor therapeutic use, Tumor Necrosis Factor-alpha antagonists & inhibitors, Withholding Treatment, Antirheumatic Agents adverse effects, Arthritis, Juvenile drug therapy, Immunoglobulin G adverse effects, Sarcoidosis chemically induced, Sarcoidosis diagnosis
Published
2013
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31. USH1G with unique retinal findings caused by a novel truncating mutation identified by genome-wide linkage analysis.

Author

Imtiaz F, Taibah K, Bin-Khamis G, Kennedy S, Hemidan A, Al-Qahtani F, Tabbara K, Al Mubarak B, Ramzan K, Meyer BF, and Al-Owain M

Subjects
Adolescent, Case-Control Studies, Child, Child, Preschool, Cochlear Implants, Consanguinity, Exons, Female, Genes, Recessive, Genetic Linkage, Genome-Wide Association Study, Humans, Male, Oligonucleotide Array Sequence Analysis, Pedigree, Retina metabolism, Saudi Arabia, Sequence Analysis, DNA, Siblings, Usher Syndromes pathology, Mutation, Nerve Tissue Proteins genetics, Retina pathology, Usher Syndromes genetics
Abstract

Purpose: Usher syndrome (USH) is an autosomal recessive disorder divided into three distinct clinical subtypes based on the severity of the hearing loss, manifestation of vestibular dysfunction, and the age of onset of retinitis pigmentosa and visual symptoms. To date, mutations in seven different genes have been reported to cause USH type 1 (USH1), the most severe form. Patients diagnosed with USH1 are known to be ideal candidates to benefit from cochlear implantation., Methods: Genome-wide linkage analysis using Affymetrix GeneChip Human Mapping 10K arrays were performed in three cochlear implanted Saudi siblings born from a consanguineous marriage, clinically diagnosed with USH1 by comprehensive clinical, audiological, and ophthalmological examinations. From the linkage results, the USH1G gene was screened for mutations by direct sequencing of the coding exons., Results: We report the identification of a novel p.S243X truncating mutation in USH1G that segregated with the disease phenotype and was not present in 300 ethnically matched normal controls. We also report on the novel retinal findings and the outcome of cochlear implantation in the affected individuals., Conclusions: In addition to reporting a novel truncating mutation, this report expands the retinal phenotype in USH1G and presents the first report of successful cochlear implants in this disease.

Published
2012

32. Risk factors associated with complications of orbital surgery in children.

Author

Salem M and Qahtani F

Subjects
Adolescent, Child, Child, Preschool, Female, Humans, Infant, Male, Risk Factors, Intraoperative Complications, Orbit surgery, Orbital Neoplasms surgery, Orbital Pseudotumor surgery, Postoperative Complications
Abstract

Purpose: To assess the overall complication rate of orbitotomies performed in children and to determine the nature of complication to identify possible risk factors., Methods: Thirty children <13 years underwent 33 orbitotomies for space-occupying lesions of the orbit or orbital decompression. A detailed evaluation of the surgical procedures and outcomes was conducted. Follow up averaged 2.5 years (range: 6 months to 5 years)., Results: The complication rate was 20% (2 of 10 cases) for anterior orbitotomies, 40% (8 of 20 cases) for primary lateral orbitotomies, and 100% (3 of 3 cases) for secondary orbitotomies. Dense amblyopia was noted in 6 of 9 patients. Major complications were frozen eyeball, diplopia, and ptosis. Less serious complications were enophthalmos, internal ophthalmoplegia, dry eye, and eyelid retraction. Six patients underwent extraocular surgery, levator muscle surgery, or both at a later date., Conclusion: Although the scope of complications is the same in children as in adults, the frequency of cystic benign lesions and small orbits in children can cause more frequent serious complications. Additionally, dense amblyopia of a complicated nature makes visual outcome unpredictable. The most significant risk factors identified were the need for a secondary procedure for recurring pathology and the presence of an intraconal lesion.

Published
2001
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33. Vertical rectus muscle transposition and botulinum toxin for complete sixth nerve palsy.

Author

Flanders M, Qahtani F, Gans M, and Beneish R

Subjects
Abducens Nerve Diseases physiopathology, Adult, Aged, Female, Humans, Male, Middle Aged, Paralysis physiopathology, Vision, Binocular, Abducens Nerve Diseases therapy, Anti-Dyskinesia Agents therapeutic use, Botulinum Toxins therapeutic use, Oculomotor Muscles surgery, Paralysis therapy
Abstract

Background: Effective surgical treatment of complete unrecovered sixth nerve palsy must include the transfer of abducting power to the temporal aspect of the globe with release of medial rectus contracture nasally. We describe our experience in the treatment of five such patients who underwent full vertical rectus transposition combined with botulinum toxin chemodenervation of the ipsilateral medial rectus muscle., Methods: The five patients all had primarily unilateral complete unrecovered sixth nerve palsy. They all underwent a complete preoperative and postoperative eye examination and an orthoptic assessment. Excursion into abduction was graded from -8 (globe immobilized in extreme adduction) to -4 (abduction as far as primary position) to 0 (full abduction). Abduction saccades and a forced muscle generation test confirmed the presence of complete unrecovered sixth nerve palsy, and forced duction testing measured the degree of medial rectus contracture. All patients received ipsilateral medial rectus injection of botulinum toxin in the preoperative (8 to 2 months before surgery) and perioperative periods, and underwent complete superior rectus-inferior rectus transposition temporally., Results: The average length of follow-up was 21 (range 6 to 48) months. The average preoperative distance alignment was 52 (range 25 to 80) prism dioptres (PD). Vertical rectus transposition combined with botulinum toxin injection resulted in an average distance alignment change of 66 PD (range 50 PD to 82 PD) of exoshift. The average final deviation was 1 PD of esotropia (range 4 PD of esotropia to 6 PD of exotropia). Average abduction improved from -6 (range -3 to -8) preoperatively to -1.7 (range -1 to -2) postoperatively. Saccades averaged -4 preoperatively and improved to -2 postoperatively. Normal vertical eye movements were preserved in all patients. A total field of single binocular vision was created in all patients, which averaged 55 degrees (range 30 degrees to 75 degrees) in the horizontal meridian. The field of single binocular vision from primary position into abduction averaged 23 degrees (range 18 degrees to 28 degrees)., Interpretation: Temporal transposition of the vertical rectus muscles combined with perioperative botulinum toxin injection of the ipsilateral medial rectus muscle is a reliable and effective way of restoring functional binocular vision in patients with complete unrecovered sixth nerve palsy.

Published
2001
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34. Intraocular gnathostomiasis: a rare Canadian case.

Author

Qahtani F, Deschênes J, Ali-Khan Z, Maclean JD, Codère F, Mansour M, and Burnier M Jr

Subjects
Administration, Oral, Albendazole administration & dosage, Albendazole therapeutic use, Animals, Anterior Chamber diagnostic imaging, Anterior Chamber parasitology, Anterior Chamber pathology, Anthelmintics administration & dosage, Anthelmintics therapeutic use, Diagnosis, Differential, Female, Humans, Middle Aged, Ultrasonography, Uveitis, Anterior diagnosis, Uveitis, Anterior drug therapy, Visual Acuity, Eye Infections, Parasitic diagnosis, Eye Infections, Parasitic drug therapy, Eye Infections, Parasitic parasitology, Gnathostoma isolation & purification, Spirurida Infections diagnosis, Spirurida Infections drug therapy, Spirurida Infections parasitology, Uveitis, Anterior parasitology
Published
2000
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