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Ladybird beetle (Coccinella septempunctata) is present in various crops like cotton, sunflower, fruit plants, and vegetables. C. septempunctata is the free living predatory specie of sucking insect pests such as aphids, mealybugs, and whiteflies and consume many preys during its lifetime. C. septempunctata larvae and adults are both active predators. The present study regarding toxicity of new chemistry insecticides against C. septempunctata was conducted under laboratory conditions. The toxic potential of six synthetic insecticides Emamectin benzoate (200ml/acre), Indoxacarb (175ml/acre), Lufenuron (200ml/acre), Spinetoram (80ml/acre), Chlorantraniliprole (50ml/acre), and Flubendiamide (50ml/acre) were tested on C. septempuctata. The leaf dip bioassay method was performed by collecting sunflower leaves and a 2cm leaf disc with larvae was dipped in insecticides. Data regarding mortality was recorded after 24, 48, 72, 96, and 120 hours. Mortality rates were as follows: 28% for emamectin benzoate, 26% for indoxacarb, 22% for lufenuron, 22% for Spinetoram, 16% for chlorantraniliprole, 14% for chlorantraniliprole, and 10% for Flubendiamide. However, Lufenuron, Spinetoram, and Chlorantraniliprole exhibited moderate toxicity, Indoxacrab and Emamectin benzoate showed severe toxicity, and Flubendiamide showed low toxicity. Our findings offer insights for integrating chemical and biological control strategies to manage sucking insect pests comprehensively. [ABSTRACT FROM AUTHOR]