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5. Características clínico-microbiológicas de las lesiones cutáneas en el paciente séptico

Author

Bouza Santiago, Emilio, Patricia Muñoz García, Patricia, Suárez Fernández, Ricardo, Pulido Pérez, Ana, Bouza Santiago, Emilio, Patricia Muñoz García, Patricia, Suárez Fernández, Ricardo, and Pulido Pérez, Ana

Abstract

La sepsis constituye una de las primeras causas de mortalidad en el mundo. El principal reto es su diagnóstico precoz. Aunque clínicamente la sepsis exhibe una amplia variedad de signos, las manifestaciones cutáneas han sido pobremente documentadas en la literatura. En dermatología la sepsis impacta en varios aspectos: por un lado, como tejido potencialmente afectado en el transcurso de las consecuencias inflamatorias y/o hemodinámicas de la sepsis y, por otro, al considerarse un órgano capaz de albergar el foco infeccioso inicial o sufrir la extensión metastásica de la infección desde otros órganos. A pesar de ello, en la literatura actual no existe información detallada y actualizada sobre la verdadera prevalencia de las manifestaciones cutáneas en los pacientes con diagnóstico de sepsis, más allá de series de casos o descripciones aisladas de cuadros clínicos o microorganismos concretos. Esta carencia dificulta la interpretación de los hallazgos comúnmente observables en la práctica clínica diaria e impide definir el impacto del compromiso cutáneo en la evaluación pronóstica del paciente séptico..., Sepsis is one of the leading causes of mortality in the world. The main challenge is its early diagnosis. Although clinically sepsis exhibits a wide variety of signs, cutaneous manifestations have been poorly documented in the literature. In dermatology, sepsis has an impact on several aspects: firstly, as a potentially affected tissue in the course of the inflammatory and/or hemodynamic consequences of sepsis and, secondly, as an organ capable of harboring the initial infectious focus or suffering the metastatic spread of the infection from other organs. Despite this, the current literature lacks detailed and updated information on the true prevalence of cutaneous manifestations in patients diagnosed with sepsis, beyond case series or isolated descriptions of clinical pictures or specific microorganisms. This scarcity of information makes it difficult to interpret the findings commonly observed in daily clinical practice and prevents us from defining the impact of cutaneous involvement in the prognostic evaluation of the septic patient...

Published
2023

7. Human monkeypox virus in a tertiary hospital in Madrid, Spain: An observational study of the clinical and epidemiological characteristics of 53 cases

Author

García‐Piqueras, Paloma, primary, Bergón‐Sendín, Marta, additional, Córdoba‐García‐Rayo, María, additional, Vírseda‐González, Daniel, additional, Medrano‐Martínez, Noelia, additional, Jiménez‐Briones, Luis, additional, Lacasta‐Plasín, Clara, additional, Hernández de la Torre‐Ruiz, Elisa, additional, Balaguer‐Franch, Inmaculada, additional, Pulido‐Pérez, Ana, additional, Molina‐López, Irene, additional, Rodríguez‐Lomba, Enrique, additional, Barchino‐Ortiz, Lucia, additional, Suárez‐Fernández, Ricardo, additional, and Nieto‐Benito, Lula María, additional

Published
2022
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9. Características clínico-microbiológicas de las lesiones cutáneas en el paciente séptico

Author

Pulido Pérez, Ana, Bouza Santiago, Emilio, Patricia Muñoz García, Patricia, Suárez Fernández, Ricardo, Pulido Pérez, Ana, Bouza Santiago, Emilio, Patricia Muñoz García, Patricia, and Suárez Fernández, Ricardo

Abstract

La sepsis constituye una de las primeras causas de mortalidad en el mundo. El principal reto es su diagnóstico precoz. Aunque clínicamente la sepsis exhibe una amplia variedad de signos, las manifestaciones cutáneas han sido pobremente documentadas en la literatura. En dermatología la sepsis impacta en varios aspectos: por un lado, como tejido potencialmente afectado en el transcurso de las consecuencias inflamatorias y/o hemodinámicas de la sepsis y, por otro, al considerarse un órgano capaz de albergar el foco infeccioso inicial o sufrir la extensión metastásica de la infección desde otros órganos. A pesar de ello, en la literatura actual no existe información detallada y actualizada sobre la verdadera prevalencia de las manifestaciones cutáneas en los pacientes con diagnóstico de sepsis, más allá de series de casos o descripciones aisladas de cuadros clínicos o microorganismos concretos. Esta carencia dificulta la interpretación de los hallazgos comúnmente observables en la práctica clínica diaria e impide definir el impacto del compromiso cutáneo en la evaluación pronóstica del paciente séptico...

Published
2022

11. Creeping eruption

Author

Pulido-Pérez, Ana, Rodríguez-Soria, Virna Judith, Horcajada-Reales, Celia, Melero, Rosa, and Suárez-Fernández, Ricardo

Published
2015
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12. Human monkeypox virus in a tertiary hospital in Madrid, Spain: An observational study of the clinical and epidemiological characteristics of 53 cases.

Author

García‐Piqueras, Paloma, Bergón‐Sendín, Marta, Córdoba‐García‐Rayo, María, Vírseda‐González, Daniel, Medrano‐Martínez, Noelia, Jiménez‐Briones, Luis, Lacasta‐Plasín, Clara, Hernández de la Torre‐Ruiz, Elisa, Balaguer‐Franch, Inmaculada, Pulido‐Pérez, Ana, Molina‐López, Irene, Rodríguez‐Lomba, Enrique, Barchino‐Ortiz, Lucia, Suárez‐Fernández, Ricardo, and Nieto‐Benito, Lula María

Subjects
MONKEYPOX, SEXUALLY transmitted diseases, ENDEMIC diseases, UNSAFE sex, HUMAN sexuality
Abstract

A new outbreak of monkeypox virus (MPXV) infection, a zoonotic infection endemic in Central and West Africa, is spreading throughout the world with new epidemiology and clinical features. Our aim was to characterize patients presenting to Dermatology emergency room with a MPXV infection between 15 May and 30 June 2022 in a tertiary hospital in Madrid, Spain. We collected 53 patients and describe their clinical, demographic and epidemiological characteristics and followed their evolution. Most of the patients were men who had sex with men with high‐risk sexual practices and no recent travels abroad. Most of them (91%) had had a sexually transmitted infection before. All patients had typical skin lesions consisting of vesicular‐pustular rash with central umbilication which was localized or disseminated. The most frequent extracutaneous symptoms were fever, painful regional lymphadenopathy and asthenia. Proctitis was present in more than one third of patients. All patients were diagnosed by real time polymerase chain reaction of samples obtained from skin lesions. Pharyngeal and/or rectal exudates demonstrated MPXV in 74% of patients. The current worldwide outbreak of MPXV infections shows epidemiological and clinical differences from previous ones. Clinicians should be aware of these characteristics to correctly diagnose this emerging disease. [ABSTRACT FROM AUTHOR]

Published
2023
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25. Histopathological findings in COVID‐19‐induced cutaneous lesions. Clinicopathological correlation of SARS‐CoV‐19 dermatologic patterns: review of the literature

Author

Nieto‐Benito, Lula María, primary, Hernández de la Torre‐Ruiz, Elisa, additional, Balaguer‐Franch, Inmaculada, additional, Rosell‐Díaz, Ángel Manuel, additional, Mateos‐Mayo, Ana, additional, Herrero‐Sanchez, Alejandro, additional, Lacasta‐Plasín, Clara, additional, García‐Piqueras, Paloma, additional, Barchino‐Ortiz, Lucía, additional, Bergón‐Sendín, Marta, additional, Pulido‐Pérez, Ana, additional, Baniandrés‐Rodríguez, Ofelia, additional, Rodriguez‐Lomba, Enrique, additional, Molina‐Lopez, Irene, additional, and Suárez‐Fernandez, Ricardo, additional

Published
2020
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30. Effectiveness of neoadjuvant intralesional methotrexate in cutaneous squamous cell carcinoma: A prospective cohorts study.

Author

Bergón‐Sendín, Marta, Pulido‐Pérez, Ana, Nieto‐Benito, Lula María, Barchino‐Ortiz, Lucía, Díez‐Sebastián, Jesús, and Suárez‐Fernández, Ricardo

Subjects
*SQUAMOUS cell carcinoma, *METHOTREXATE, *LONGITUDINAL method, *COHORT analysis, *NEOADJUVANT chemotherapy
Abstract

Intralesional methotrexate (il‐MTX) has been used in cutaneous squamous cell carcinoma (cSCC) achieving important reductions in tumor size. However, there is a lack of controlled studies on this regard. The primary objective was to analyze the effect of il‐MTX on tumor size in cSCC. As a secondary objective, we evaluated its impact on the surgical approach. We conducted a prospective cohorts study that included 200 patients with histologically confirmed cSCC. Patients in Group 1 (Cases) received neoadjuvant treatment with il‐MTX prior to surgery. Patients in Group 2 (Controls) underwent scheduled surgery without prior neoadjuvant therapy. Clinical measurements of lesions were made at the time of inclusion in the study and before surgery. No intergroup statistical differences were found between the assessed variables. In Group 1, tumor size reduction occurred in 93% of the patients after il‐MTX therapy. Tumor surface was reduced by 54%. Complex reconstructions were needed in 15% of these patients. In Group 2, tumor surface increased by 33.1% and complex reconstructions were needed in 40% of patients. Intergroup differences were statistically significant (p < 0.001). Neoadjuvant Il‐MTX therapy achieves very important tumor size reduction and significantly simplifies surgical treatment. [ABSTRACT FROM AUTHOR]

Published
2022
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39. Histopathological findings in COVID‐19‐induced cutaneous lesions. Clinicopathological correlation of SARS‐CoV‐19 dermatologic patterns: review of the literature.

Author

Nieto‐Benito, Lula María, Hernández de la Torre‐Ruiz, Elisa, Balaguer‐Franch, Inmaculada, Rosell‐Díaz, Ángel Manuel, Mateos‐Mayo, Ana, Herrero‐Sanchez, Alejandro, Lacasta‐Plasín, Clara, García‐Piqueras, Paloma, Barchino‐Ortiz, Lucía, Bergón‐Sendín, Marta, Pulido‐Pérez, Ana, Baniandrés‐Rodríguez, Ofelia, Rodriguez‐Lomba, Enrique, Molina‐Lopez, Irene, and Suárez‐Fernandez, Ricardo

Subjects
COVID-19, LITERATURE reviews
Abstract

An increasing number of publications have brought attention to COVID‐19‐associated cutaneous lesions. Histopathological descriptions and clinical correlation of the histopathological findings of COVID‐19 skin lesions are lacking. In this manuscript, we reviewed and described the histopathological characteristics of COVID‐19 infection cutaneous patterns reported in the literature. [ABSTRACT FROM AUTHOR]

Published
2021
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40. Infiltración cutánea por leucemia prolinfocítica T en dos pacientes adultos.

Author

Mateos-Mayo, Ana, Sánchez-Herrero, Alejandro, María Nieto-Benito, Lula, Parra-Blanco, Verónica, Suárez-Fernández, Ricardo, and Pulido-Pérez, Ana

Abstract

Copyright of Revista Medica del IMSS is the property of Direccion de Prestaciones Medicas - IMSS and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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