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4. Treatment of Psoriasis Patients with Latent Tuberculosis Using IL-17 and IL-23 Inhibitors: A Retrospective, Multinational, Multicentre Study

Author

Torres, Tiago, Chiricozzi, Andrea, Puig, Luis, Lé, Ana Maria, Marzano, Angelo Valerio, Dapavo, Paolo, Dauden, Esteban, Carrascosa, Jόse-Manuel, Lazaridou, Elizabeth, Duarte, Gleison, Carvalho, André V. E., Romiti, Ricardo, Rompoti, Natalia, Teixeira, Laetitia, Abreu, Miguel, Ippoliti, Elena, Maronese, Carlo Alberto, Llamas-Velasco, Mar, Vilarrasa, Eva, del Alcázar, Elena, Daponte, Athina-Ioanna, Papoutsaki, Marina, Carugno, Andrea, Bellinato, Francesco, and Gisondi, Paolo

Published
2024
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6. The Virtual Body in a Design Exercise: A Conceptual Framework for Embodied Cognition

Author

Mejia-Puig, Luis and Chandrasekera, Tilanka

Abstract

In design education, immersive virtual reality (VR) has grown as a visualization and interaction tool. Nonetheless, little research has been done on how individuals self-perception within VR affects their performance. This self-awareness is carried out using avatars that depict the virtual body through multiple points of view. This article assessed three different conditions of virtual body within a design exercise to better understand how these affected idea generations and spatial skills. To do so, an embodiment-cognition framework to evaluate the influence of the virtual body in immersive VR environments was developed. The designed theoretical framework relies on the concept of embodiment and its relevance to situated cognition. Research has supported how cognition connects the mind and body and the relevance of the individual's interaction with its surroundings to make it meaningful. Likewise, more immersive environments can increase the sensation of presence in VR, allowing individuals to behave more naturally. Also, through the connection with the surroundings, individuals liberate cognitive load, allowing them to relocate cognitive efforts in developing knowledge. General findings support how the use of a more embodied virtual body can elicit higher levels of presence but also increase cognitive load which can ultimately hinder cognition. However, VR interactions aided participants to develop spatial skills and allowed idea generation. Furthermore, the framework proposed can be applied to assess students' cognitive processes beyond the discipline's boundaries.

Published
2023
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7. Perception over the Use of Traditional and Digital Mediums within the Design Process: A Questionnaire Study on Design Students

Author

Mejia-Puig, Luis Alfonso, Arango, Hugo Dario, and Chandrasekera, Tilanka

Abstract

The purpose of this study was to explore design student's perceptions over traditional and digital mediums within the design process. In this research, a convenient sample of design students was selected from two universities between Latin America and North America to respond a questionnaire which inquired for the design steps and the type of tools they used. The importance of traditional medium in the design process has been widely researched (e.g. Goldschmidt, 1991; Suwa et al., 1998; Tang & Gero, 2002). In a similar manner, digital medium has evolved in the design practice and researchers have looked at how the use of digital tools affect the design process (Salman, et al.2014). Multiple studies have argued that some stages of this process cannot be supported by digital medium tools (e.g. Bilda & Demirkan, 2003; Kwon, et al., 2005; Meniru, et al., 2003; Stones & Cassidy, 2007). In contrast, digital medium stimulates the occurrence of design patterns and epistemic actions (Yu, et al. 2015: Chandrasekera, 2014). Digital medium will require the development of new knowledge which may affect the designer's role and the education practices of new designers. The outcomes of this study will help design educators to understand design students' preferences in using digital tools and develop curriculums accordingly. In addition, it will aid software developers to better understand, cater to design students' needs and take advantage in the growing shift from traditional to digital medium.

Published
2022

16. Drug Survival of Interleukin (IL)‑17 and IL‑23 Inhibitors for the Treatment of Psoriasis: A Retrospective Multi‑country, Multicentric Cohort Study

Author

Torres, Tiago, Puig, Luis, Vender, Ron, Yeung, Jensen, Carrascosa, José-Manuel, Piaserico, Stefano, Gisondi, Paolo, Lynde, Charles, Ferreira, Paulo, Bastos, Pedro Mendes, Dauden, Esteban, Leite, Luiz, Valerio, Joana, del Alcázar-Viladomiu, Elena, Rull, Eva Vilarrasa, Llamas-Velasco, Mar, Pirro, Federico, Messina, Francesco, Bruni, Manfredo, Licata, Gaetano, Ricceri, Federica, Nidegger, Alessia, Hugo, Jan, Mufti, Asfandyar, Daponte, Athina-Ioanna, Teixeira, Laetitia, Balato, Anna, Romanelli, Marco, Prignano, Francesca, Gkalpakiotis, Spyridon, Conrad, Curdin, Lazaridou, Elizabeth, Rompoti, Natalia, Papoutsaki, Marina, Nogueira, Miguel, and Chiricozzi, Andrea

Published
2022
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18. Age affects drug survival rates of interleukin (IL)‐17 and IL‐23 inhibitors in patients with plaque psoriasis: Results from a retrospective, multicentric, multi‐country, cohort study

Author

Chiricozzi, Andrea, primary, Coscarella, Giulia, additional, Puig, Luis, additional, Vender, Ron, additional, Yeung, Jensen, additional, Carrascosa, José‐Manuel, additional, Piaserico, Stefano, additional, Gisondi, Paolo, additional, Lynde, Charles, additional, Ferreira, Paulo, additional, Bastos, Pedro Mendes, additional, Dauden, Esteban, additional, Leite, Luiz, additional, Valerio, Joana, additional, del Alcázar‐Viladomiu, Elena, additional, Vilarrasa, Eva, additional, Llamas‐Velasco, Mar, additional, Alessandri‐Bonetti, Mario, additional, Messina, Francesco, additional, Bruni, Manfredo, additional, Di Brizzi, Eugenia Veronica, additional, Ricceri, Federica, additional, Nidegger, Alessia, additional, Hugo, Jan, additional, Mufti, Asfandyar, additional, Daponte, Athina‐Ioanna, additional, Teixeira, Laetitia, additional, Balato, Anna, additional, Romanelli, Marco, additional, Prignano, Francesca, additional, Gkalpakiotis, Spyridon, additional, Conrad, Curdin, additional, Lazaridou, Elizabeth, additional, Rompoti, Natalia, additional, Stratigos, Alexander J., additional, Nogueira, Miguel, additional, Peris, Ketty, additional, and Torres, Tiago, additional

Published
2024
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24. P28 Drug-induced lupus: clinical and serological features in a tertiary hospital

Author

Leal, Samuel, primary, Álvarez, Iago Alcántara, additional, Verdejo, Inmaculada Chalmeta, additional, Charia, Hikmat, additional, Navarro, Marta de la Rubia, additional, Puig, Luis González, additional, García, Elena Grau, additional, Huaylla Quispe, Anderson Víctor, additional, Cortés, José Ivorra, additional, Cordellat, Isabel Martínez, additional, Sánchez, Laura Mas, additional, Muñoz Martínez, Pablo Francisco, additional, Albuixech, Rosa Negueroles, additional, Oller Rodríguez, José Eloy, additional, Castro, Daniel Ramos, additional, Bárcena, Carmen Riesco, additional, Novés, Alba Torrat, additional, Sugrañes, Ernesto Tovar, additional, Bernabeu, Elvira Vicens, additional, Mañes, Belén Villanueva, additional, Olmos, Inés Cánovas, additional, Herranz, Carmen Nájera, additional, and Román Ivorra, José Andrés, additional

Published
2024
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25. P9 Increase of IL10 and INFA2 are associated to clinical activity in systemic lupus erythematous patients

Author

García, Elena Grau, primary, Álvarez, Iago Alcántara, additional, Verdejo, Inmaculada Chalmeta, additional, Charia, Hikmat, additional, Navarro, Marta de la Rubia, additional, Puig, Luis González, additional, Huaylla Quispe, Anderson Víctor, additional, Cortés, José Ivorra, additional, Leal, Samuel, additional, Cordellat, Isabel Martínez, additional, Sánchez, Laura Mas, additional, Muñoz Martínez, Pablo Francisco, additional, Albuixech, Rosa Negueroles, additional, Oller Rodríguez, José Eloy, additional, Castro, Daniel Ramos, additional, Bárcena, Carmen Riesco, additional, Novés, Alba Torrat, additional, Sugrañes, Ernesto Tovar, additional, Bernabeu, Elvira Vicens, additional, Mañes, Belén Villanueva, additional, Olmos, Inés Cánovas, additional, Herranz, Carmen Nájera, additional, Urmeneta, Guillen Sada, additional, and Román Ivorra, José Andrés, additional

Published
2024
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26. P149 Clinical worsening in non-adherent belimumab treatment in SLE

Author

Navarro, Marta de la Rubia, primary, García, Elena Grau, additional, Monreal, Ma Jesús Cuellar, additional, Álvarez, Iago Alcántara, additional, Verdejo, Inmaculada Chalmeta, additional, Charia, Hikmat, additional, Puig, Luis González, additional, Huaylla Quispe, Anderson Víctor, additional, Cortés, José Ivorra, additional, Leal, Samuel, additional, Cordellat, Isabel Martínez, additional, Sánchez, Laura Mas, additional, Muñoz Martínez, Pablo Francisco, additional, Albuixech, Rosa Negueroles, additional, Oller Rodríguez, José Eloy, additional, Castro, Daniel Ramos, additional, Bárcena, Carmen Riesco, additional, Novés, Alba Torrat, additional, Sugrañes, Ernesto Tovar, additional, Bernabeu, Elvira Vicens, additional, Mañes, Belén Villanueva, additional, Olmos, Inés Cánovas, additional, Herranz, Carmen Nájera, additional, and Román Ivorra, José Andrés, additional

Published
2024
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28. Sequelae following infantile haemangiomas treated with propranolol

Author

Baselga, Eulalia, El Hachem, May, Diociaiuti, Andrea, Carnevale, Claudia, Downey, Camila, Roe, Esther, Mascaro, Patricia, Neri, Iria, Leuzzi, Miriam, Bernabeu-Wittel, José, Monserrat-García, Maria Teresa, Ortiz-Prieto, Alejandro, Torrelo, Antonio, Knopfel, Nicole, Vercellino, Nadia, Manunza, Francesca, Oranges, Teresa, Bassi, Andrea, Gonzalez-Enseñat, Maria Antonia, Vicente, Asunción, Gich, Ignasi, and Puig, Luis

Published
2021
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30. Estimating 3D Trajectories from 2D Projections via Disjunctive Factored Four-Way Conditional Restricted Boltzmann Machines

Author

Mocanu, Decebal Constantin, Ammar, Haitham Bou, Puig, Luis, Eaton, Eric, and Liotta, Antonio

Subjects
Computer Science - Computer Vision and Pattern Recognition, Computer Science - Artificial Intelligence
Abstract

Estimation, recognition, and near-future prediction of 3D trajectories based on their two dimensional projections available from one camera source is an exceptionally difficult problem due to uncertainty in the trajectories and environment, high dimensionality of the specific trajectory states, lack of enough labeled data and so on. In this article, we propose a solution to solve this problem based on a novel deep learning model dubbed Disjunctive Factored Four-Way Conditional Restricted Boltzmann Machine (DFFW-CRBM). Our method improves state-of-the-art deep learning techniques for high dimensional time-series modeling by introducing a novel tensor factorization capable of driving forth order Boltzmann machines to considerably lower energy levels, at no computational costs. DFFW-CRBMs are capable of accurately estimating, recognizing, and performing near-future prediction of three-dimensional trajectories from their 2D projections while requiring limited amount of labeled data. We evaluate our method on both simulated and real-world data, showing its effectiveness in predicting and classifying complex ball trajectories and human activities., Comment: Pattern Recognition, ISSN 0031-3203, Elsevier, 2017

Published
2016
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31. Treatment-emergent Candida infections in patients with psoriasis, psoriatic arthritis, and axial spondyloarthritis treated with ixekizumab: an integrated safety analysis of 25 clinical studies

Author

Schwartzman, Sergio, Puig, Luis, Cohen, Arnon D., Khattri, Saakshi, Jossart, Christian, Diaz, Carlos, Garrelts, Alyssa, Ngantcha, Marcus, Eberhart, Nadezhda, Eleftheriadi, Areti, Tangsirisap, Nithi, Schuster, Christopher, and Gottlieb, Alice B.

Abstract

ABSTRACTBackgroundThis safety analysis investigates treatment-emergent mucosal/cutaneous Candida infections in patients treated with ixekizumab (IXE), an anti-interleukin-17A monoclonal antibody, across the approved indications: psoriasis (PsO), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA).Research design and methodsSafety data were pooled from 25 clinical studies. Incidence rates (IRs) are expressed as per 100 patient-years (PY), using the entire duration of exposure.ResultsCandida infections had an IR of 1.9 per 100 PY in patients with PsO (N = 6892; total PY = 18025.7), 2.0 per 100 PY in patients with PsA (N = 1401; total PY = 2247.7), and 1.2 per 100 PY in patients with axSpA (N = 932; total PY = 2097.7). The majority of treatment-emergent Candida infections were: (i) experienced only once by patients (IR = 1.3;IR = 1.6;IR = 1.0), (ii) mild/moderate in severity (IR = 0.8/0.9;IR = 1.5/0.4;IR = 0.8/0.5) as opposed to severe (IR = 0.0; IR = 0.0; IR = 0.0), (iii) oral Candida or genital Candida (IR = 0.9/0.6;IR = 1.0/0.7;IR = 0.4/0.6), (iv) marked as recovered/resolved during the studies (89.3%;93.8%;90.3%), (v) not leading to IXE discontinuation (0.0%;0.0%;0.1% discontinued), (vi) managed with topical (34.7%;22.2%;11.5%) or no anti-fungal medications (63.5%;77.8%;80.8%) as opposed to systemic therapies (1.5%;0.0%;7.7%), (vii) typically resolved before next visit.ConclusionsThis integrated safety analysis shows that the risk of developing Candida infections is low with IXE, and the severity is mild-to-moderate in most instances across the approved IXE indications.Trial registrationA comprehensive list of the clinical trials and their registration numbers is reported in Table S1 of the supplemental material.

Published
2024
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34. Drug Survival of IL-12/23, IL-17 and IL-23 Inhibitors for Psoriasis Treatment: A Retrospective Multi-Country, Multicentric Cohort Study

Author

Torres, Tiago, Puig, Luis, Vender, Ron, Lynde, Charles, Piaserico, Stefano, Carrascosa, Jose M., Gisondi, Paolo, Daudén, Esteban, Conrad, Curdin, Mendes-Bastos, Pedro, Ferreira, Paulo, Leite, Luiz, Lu, Justin D., Valerio, J., Bruni, M., Messina, F., Nidegger, A., Llamas-Velasco, M., del Alcazar, E., Mufti, A., White, Kyra, Caldarola, G., Teixeira, Laetitia, Romanelli, Paolo, Desai, K., Gkalpakiotis, Spyridon, Romanelli, Marco, Yeung, Jensen, Nogueira, Miguel, and Chiricozzi, Andrea

Published
2021
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36. The prevalence of skin diseases in Greece, impact on quality of life and stigmatization:A population-based survey study

Author

Stratigos, Alexander J., Richard, Marie A., Dessinioti, Clio, Paul, Carle, Nijsten, Tamar, Gisondi, Paolo, Salavastru, Carmen, Taieb, Charles, Trakatelli, Myrto, Puig, Luis, Tzellos, Thrasyvoulos, Ioannides, Dimitrios, Stratigos, Alexander J., Richard, Marie A., Dessinioti, Clio, Paul, Carle, Nijsten, Tamar, Gisondi, Paolo, Salavastru, Carmen, Taieb, Charles, Trakatelli, Myrto, Puig, Luis, Tzellos, Thrasyvoulos, and Ioannides, Dimitrios

Abstract

Background: There is no population-based evidence on the prevalence and impact of skin diseases in Greece. Objectives: To describe the prevalence of 12 main skin diseases and their impact on quality of life (QoL) and feelings of stigmatization in the Greek population. Methods: A population-based survey in an adult Greek representative sample was carried out as part of the multinational ‘EADV burden of skin diseases study’. Quality of life (QOL) was measured using the Dermatology Life Quality Index (DLQI) and the Visual Analogue Scale (VAS) from the EuroQol-5D (EQ. 5D) questionnaires. Results: In 1010 participants, 47.8% (n = 483) declared at least one skin disease or condition or skin-related unpleasant sensation in the last 12 months. Fungal skin infection was reported with the higher prevalence (7.5%), followed by alopecia (5.7%), atopic dermatitis (5%), acne (3.6%), sexually transmitted diseases (2.7%), psoriasis (2.2%) chronic urticaria (1.5%), rosacea (1.3%), nonmelanoma skin cancer (1.5%), vitiligo (0.6%), cutaneous melanoma (0.6%) and hidradenitis suppurativa (0.3%). Mean VAS-EQ. 5D and DLQI scores were 77.8 and 2.2, respectively. Among those reporting at least one skin problem, 68.1% reported an impact of the skin condition on their personal life and 51% reported an impact on time to take care of themselves. Regarding the impact on work-life decisions, 22.2% reoriented their professional activity, 13% were refused a professional offer, 22.2% did not get the job they hoped to and 16.7% chose their work with their skin problem in mind. Regarding feelings of stigmatization, 12% felt left out/rejected by others, 6.6% were refused access to leisure facilities and 9.8% reported the impression to be looked at with disgust. Conclusions: Our population-based study provides new information on the prevalence of skin diseases in the Southern European country of Greece and highlights the impact of prevalent skin disease on life-altering decisions and stigmatization.

Published
2024

37. Effect of Degrees of Freedom on the Sense of Presence Generated by Virtual Reality (VR) Head-Mounted Display Systems: A Case Study on the Use of VR in Early Design Studios

Author

Chandrasekera, Tilanka, Fernando, Kinkini, and Puig, Luis

Abstract

The purpose of this research was to explore the use of virtual reality (VR) in early design studios. In this research project, two different types of Head-Mounted Display (HMD) systems were used. One type of HMD provided six degrees of freedom and the other HMD provided three degrees of freedom. The research findings provide comparison on the functionality of the different types of HMDs and the sense of presence in VR environments. Sense of presence is defined as the sense of "being there" in a computer-simulated environment. The outcomes of this research are (a) development of a new presence questionnaire that focuses on newer VR systems and (b) understanding student perception of using VR in design projects.

Published
2019
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40. Efficacy Comparison of Targeted Systemic Monotherapies Including Lebrikizumab for Moderate-to-Severe Atopic Dermatitis: a Network Meta-Analysis

Author

Silverberg, Jonathan, primary, Bieber, Thomas, additional, Paller, Amy, additional, Beck, Lisa, additional, Kamata, Masahiro, additional, Puig, Luis, additional, Wiseman, Marni, additional, Ezzedine, Khaled, additional, Foley, Peter, additional, Johansson, Erin, additional, Dossenbach, Martin, additional, Akmaz, Bülent, additional, Casillas, Marta, additional, Karlsson, Andrei, additional, and Chovatiya, Raj, additional

Published
2024
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41. Bimekizumab Continuous Maintenance of Eesponse at Every Visit Through Two Years in Patients with Moderate to Severe Plaque Psoriasis: Post-hoc Results from Five Phase 3/3b Trials

Author

Blauvelt, Andrew, primary, Conrad, Curdin, additional, Costanzo, Antonio, additional, Van de Kerkhof, Peter, additional, Han, George, additional, Langley, Richard G., additional, Davis, Leah, additional, Hoepken, Bengt, additional, Wiegratz, Susanne, additional, and Puig, Luis, additional

Published
2024
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45. Pimecrolimus in atopic dermatitis: Consensus on safety and the need to allow use in infants

Author

Luger, Thomas, Boguniewicz, Mark, Carr, Warner, Cork, Michael, Deleuran, Mette, Eichenfield, Lawrence, Eigenmann, Philippe, Fölster-Holst, Regina, Gelmetti, Carlo, Gollnick, Harald, Hamelmann, Eckard, Hebert, Adelaide A, Muraro, Antonella, Oranje, Arnold P, Paller, Amy S, Paul, Carle, Puig, Luis, Ring, Johannes, Siegfried, Elaine, Spergel, Jonathan M, Stingl, Georg, Taieb, Alain, Torrelo, Antonio, Werfel, Thomas, and Wahn, Ulrich

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Aging, Pediatric, Skin, Anti-Inflammatory Agents, Non-Steroidal, Child, Preschool, Consensus, Dermatitis, Atopic, Humans, Infant, Practice Guidelines as Topic, Tacrolimus, atopic dermatitis, eczema, infants, paediatric, pimecrolimus, safety, tacrolimus, topical calcineurin inhibitors, topical corticosteroids, Immunology, Paediatrics and Reproductive Medicine, Public Health and Health Services, Allergy, Paediatrics
Abstract

Atopic dermatitis (AD) is a distressing dermatological disease, which is highly prevalent during infancy, can persist into later life and requires long-term management with anti-inflammatory compounds. The introduction of the topical calcineurin inhibitors (TCIs), tacrolimus and pimecrolimus, more than 10 yr ago was a major breakthrough for the topical anti-inflammatory treatment of AD. Pimecrolimus 1% is approved for second-line use in children (≥2 yr old) and adults with mild-to-moderate AD. The age restriction was emphasized in a boxed warning added by the FDA in January 2006, which also highlights the lack of long-term safety data and the theoretical risk of skin malignancy and lymphoma. Since then, pimecrolimus has been extensively investigated in short- and long-term studies including over 4000 infants (

Published
2015

46. RGB-D Based Tracking of Complex Objects

Author

Perez-Yus, Alejandro, Puig, Luis, Lopez-Nicolas, Gonzalo, Guerrero, Jose J., Fox, Dieter, Hutchison, David, Series Editor, Kanade, Takeo, Series Editor, Kittler, Josef, Series Editor, Kleinberg, Jon M., Series Editor, Mattern, Friedemann, Series Editor, Mitchell, John C., Series Editor, Naor, Moni, Series Editor, Pandu Rangan, C., Series Editor, Steffen, Bernhard, Series Editor, Terzopoulos, Demetri, Series Editor, Tygar, Doug, Series Editor, Weikum, Gerhard, Series Editor, Wannous, Hazem, editor, Pala, Pietro, editor, Daoudi, Mohamed, editor, and Flórez-Revuelta, Francisco, editor

Published
2018
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47. Clinical and genetic differences between pustular psoriasis subtypes

Author

Twelves, Sophie, Mostafa, Alshimaa, Dand, Nick, Burri, Elias, Farkas, Katalin, Wilson, Rosemary, Cooper, Hywel L., Irvine, Alan D., Oon, Hazel H., Kingo, Külli, Köks, Sulev, Mrowietz, Ulrich, Puig, Luis, Reynolds, Nick, Tan, Eugene Sern-Ting, Tanew, Adrian, Torz, Kaspar, Trattner, Hannes, Valentine, Mark, Wahie, Shyamal, Warren, Richard B., Wright, Andrew, Bata-Csörgő, Zsuzsa, Szell, Marta, Griffiths, Christopher E.M., Burden, A. David, Choon, Siew-Eng, Smith, Catherine H., Barker, Jonathan N., Navarini, Alexander A., and Capon, Francesca

Published
2019
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48. Dose escalation of biologic treatment in patients with moderate‐to‐severe psoriasis in Japan.

Author

Tada, Yayoi, Soliman, Ahmed M., Ishii, Kanako, Sakuma, Ryuta, Pinter, Andreas, Davis, Matthew, Nunag, Dominic, Buessing, Marric, Puig, Luis, and Imafuku, Shinichi

Subjects
DRUG dosage, PSORIASIS, MULTIVARIABLE testing, BIOLOGICALS, THERAPEUTICS
Abstract

Patients receiving interleukin (IL)‐inhibiting biologics for moderate‐to‐severe psoriasis (PsO) may be treated with escalated doses to optimize outcomes. This study evaluated escalation prevalence in a Japanese claims analysis of patients with PsO diagnosis preceding IL‐inhibiting biologic treatment and ≥1 post‐induction maintenance claim (index date) with sufficient data availability from January 2014 to May 2022. Patients with non‐persistence were excluded. Expected daily dose (EDD) was calculated as the recommended maintenance dose divided by the treatment interval. Dose escalation was defined as ≥2 claims showing a ≥20% increase in the observed average daily dose (ADD) over the EDD (with sensitivities requiring ≥1 claim and ≥30%). Significant differences were tested using multivariable regressions. The study included 982 unique patients treated with brodalumab (BRO; n = 104), guselkumab (GUS; n = 207), ixekizumab (IXE; n = 159), risankizumab (RIS; n = 135), secukinumab (SEC; n = 215) and ustekinumab (UST; n = 196). Within 12 months, dose escalation was observed for all IL‐inhibiting biologics other than GUS and RIS: 44.4% for UST, 37.2% for IXE, 3.4% for SEC and 1.4% for BRO. In multivariable‐adjusted analyses, odds of dose escalation were significantly lower for all products relative to UST. In sensitivities, escalation was observed for all products except RIS. [ABSTRACT FROM AUTHOR]

Published
2024
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50. Corrigendum: The paradigm of IL-23-independent production of IL-17F and IL-17A and their role in chronic inflammatory diseases

Author

Navarro-Compán, Victoria, primary, Puig, Luis, additional, Vidal, Silvia, additional, Ramírez, Julio, additional, Llamas-Velasco, Mar, additional, Fernández-Carballido, Cristina, additional, Almodóvar, Raquel, additional, Pinto, José Antonio, additional, Galíndez-Aguirregoikoa, Eva, additional, Zarco, Pedro, additional, Joven, Beatriz, additional, Gratacós, Jordi, additional, Juanola, Xavier, additional, Blanco, Ricardo, additional, Arias-Santiago, Salvador, additional, Sanz, Jesús Sanz, additional, Queiro, Rubén, additional, and Cañete, Juan D., additional

Published
2023
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