1,245,009 results on '"Psychiatry and Mental health"'
Search Results
2. Task Sharing to Expand Access to Care: Development of a Behavioral Health Support Specialist
- Author
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Brenna N. Renn, Cameron Casey, Patrick J. Raue, Patricia A. Areán, and Anna Ratzliff
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Psychotherapy ,Mental Health Services ,Psychiatry ,Psychiatry and Mental health ,Mental Health ,Mental Disorders ,education ,Humans ,Delivery of Health Care ,Article ,United States ,Health Services Accessibility - Abstract
Task sharing improves access to mental health care in many countries, but little formative research has examined uptake in the United States. This Open Forum proposes the development of nonspecialist professional roles to deliver low-intensity behavioral interventions for common mental health conditions in U.S. settings such as primary care. Using data from a multilevel stakeholder assessment, the authors discuss findings and challenges associated with such a role. Key themes from stakeholder surveys concerned scope of practice, competencies, pragmatic concerns, and training needs. Although stakeholders generally found this role to be acceptable and feasible, the themes raised will be critical to developing and implementing such a role.
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- 2024
3. Hyperhomocysteinemia in Treatment with Atypical Antipsychotics is Independent of Metabolic Syndrome
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Emre SARANDÖL, Meral DEMİRCİ AKGÜN, Aslı SARANDÖL, and Esma GÜR
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Psychiatry and Mental health ,Biological Psychiatry - Abstract
Strong association between homocysteine (Hcy) and metabolic syndrome (MetS) is documented in individuals with schizophrenia and it is suggested that alterations in Hcy levels might be secondary to metabolic changes induced by atypical antipsychotics (AA). Serum paraoxonase (PON-1) activity, which is negatively affected by increased Hcy concentrations are lower in schizophrenia, and this may impact the development of metabolic side effects. Forty-five subjects with schizophrenia and 43 healthy volunteers, matched according to age, gender, smoking habits, and MetS predictors, were enrolled in this study to examine how Hcy level, PON-1 activity, and MetS indicators influence each other in schizophrenic individuals on AA treatment. Serum Hcy concentrations were significantly higher (15 ± 8 μmol/L vs 12 ± 3 μmol/L), and PON activity tended to be impaired (182±82 U/L vs 216 ± 110 U/L) in schizophrenia. Serum Hcy concentrations were not different between subjects with and without metabolic syndrome in study (14±4 μmol/L and 16±9 μmol/L) and control groups (12±3 μmol/L and 13±7 μmol/L), respectively. Similarly, PON and aryl esterase (AE) activities were not different between subjects with and without metabolic syndrome in study (PON: 185±100 U/L and 181±76 U/L; AE: 84±34 kU/L and 89±20 kU/L) and control (PON: 215±111 U/L and 216±113 U/L; AE: 83±27 kU/L and 88±33 kU/L) groups, respectively. . Hcy levels and MetS predictors were not statistically correlated. Results indicate that schizophrenic subjects on AA treatment have increased levels of Hcy compared to healthy controls and this is not influenced by the presence of MetS.
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- 2023
4. Development of Marital Conflict Areas Index and the Conflict Styles Inventory: Reliability and Validity Studies
- Author
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Nurten KARACAN ÖZDEMİR, Cemre ERTEN TATLI, Yaşar ÖZBAY, Ufuk AKBAŞ, Zeynep HATİPOĞLU SÜMER, N. Büşra AKÇABOZAN KAYABOL, Pınar ÇAĞ, Gökçen AYDIN, and Esra EKER DURMUŞ
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
The purpose of this study is to develop the Conflict Areas Index (CAI) to identify possible conflict areas that couples experience in their marriages and to develop the Conflict Styles Inventory (CSI) to assess how they deal with these conflicts. Exploratory (N=374) and confirmatory (N=152) factor analysis and test-retest (N=49) examinations were conducted with a sample of 575 married individuals in total. For the first scale, principal component analysis (PCA) was used to examine the construct validity of the CAI. According to the results, a single component giving frequency values for 15 different conflict areas was identified. In the criterion-related validity studies, the scale had a significant, negative, and strong correlation with the Relationship Assessment Scale (RAS) (r=-.72) and the level of satisfaction with the relationship (r=-.67). The Cronbach's alpha coefficient was found as .91. For the second scale, the construct validity of the CSI was examined using Exploratory Factor Analysis. The results revealed a three-dimensional structure named destructive, passive, and active conflict resolution styles. In the criterion-related validity studies, it was found significant and positive correlations between destructive (r=.14) and passive (r=.18) conflict resolution styles with CAI scores and a significant and negative correlation between active resolution style with CAI scores. In addition, there were significant and negative correlations between destructive (r=-.15) and passive (r=-.12) conflict resolution styles with the RAS scores and a significant and positive correlation between active conflict resolution style with the RAS scores. The Cronbach's alpha coefficients were .88, .87, and .87 for destructive, passive, and active conflict resolution styles, respectively. The correlation values between the scores of the CSI within a 14-day time interval were ⍴=.94, ⍴=.91, and ⍴=.83 for destructive, passive, and active conflict resolution styles, respectively. These results indicated that CAI and CSI have sufficient psychometric properties that can be used to assess conflict areas and conflict resolution styles of married individuals.
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- 2023
5. Determination of First Object Relations and Emotion Regulation Difficulties in Borderline Personality Disorder with Objective and Projective Methods
- Author
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Haydeh FARAJİ, Dr. Öğretmen. Üyesi Hatice Nevzat MUHTAR, and Ahmet Ertan TEZCAN
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Psychiatry and Mental health ,Biological Psychiatry - Abstract
Evaluation of the disorders in the personality organization of the individual is only possible by examining the object relations functions, and it is known that the elimination of emotion regulation difficulties (ERD) has a central role in the treatment of borderline personality disorder (BPD). Therefore, this study, in which objective and projective methods were used together, was designed to determine the ERD of BPD patients and the relationship between the patients' object relations and emotion regulation difficulties. It is thought that the results of the study can be useful in the psychotherapy processes of BPD patients. For this purpose, the Sociodemographic Data Form, Rorschach Test, and Emotion Regulation Difficulty Scale developed by the researchers were applied to 37 individuals diagnosed with Borderline Personality Disorder according to DSM-5 criteria and 37 individuals who did not have any psychiatric diagnosis as a result of their psychiatric examination by a psychiatrist. As a result of the study, it was determined that there was a significant relationship between BPD and ERD, and this relationship could be determined through the Rorschach test, and it was determined that BPD constituted 55% of the variance of ERD. ERD, which can have significant disruptive effects on the lives of borderline patients, was associated with the patients' lack of satisfaction and inclusion in their relations with their first object, which is usually their parents, and it was determined negative qualities of first objects accounted for 23% of the variance of difficulty in emotion regulation. It is thought that the results of the study may contribute to the acceleration of the solution of interpersonal problems, which have a close relationship with ERD, of the patients and the standardization of the Rorschach Test.
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- 2023
6. Sanat Etkinliklerine Dayalı Dışavurum Temelli Grupla Psikolojik Danışmanın Ergenlerin Öz-Yeterliklerine Etkisi
- Author
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Merve ÇALIK and Türkan DOĞAN
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
The aim of this study was to examine the effect of expression-based group counseling through art activities on adolescents' self-efficacy. A total of 16 male students aged 14-15 years, 8 in the experimental group and 8 in the control group, participated in the study. A partially mixed simultaneous equal-status design, one of the mixed design models, was used in the study. In the quantitative dimension of the study, the Self-Efficacy Scale for Children was administered to collect data. In the qualitative dimension of the study, the researcher's observations were utilized. According to the results of the study, it was concluded that there was a significant difference between the pre-test and post-test scores of the experimental group in favor of the post-test and that there was a significant difference between the experimental and control groups. Therefore, expression-based group counseling can be considered to be effective in increasing adolescents' self-efficacy.
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- 2023
7. Chronic Pain Experience According to the Transactional Stress and Coping Model: Associations between Different Pain Measures and Health Outcomes
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Ayla HOCAOĞLU UZUNKAYA and H. Özlem SERTEL BERK
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Psychiatry and Mental health ,Biological Psychiatry - Abstract
According to Lazarus and Folkman's Transactional Stress and Coping Model, chronic pain is defined as a source of stress. The model emphasizes the interaction between the person and the environment and focuses on primary (pain severity and/or frequency) and secondary appraisals (pain and/or discomfort from pain) when examining the effects of a stressor on a person's life. In this study, chronic pain was defined as a type of stress and pain stress was measured in three different ways: unidimensional pain stress (primary appraisal only), multidimensional pain stress (sum of both primary and secondary appraisals), and transactional pain stress (product of both primary and secondary appraisals). The aim of the study was to examine the relationships between the three different pain stress measures and the outcome variables of pain-related disability, negative mood and daily activity level. The study was conducted with 167 individuals with different types of chronic pain. Sociodemographic Characteristics and Pain Information Form, Visual Analog Scale, West Haven Yale Multidimensional Pain Inventory and Life Changes Questionnaire were used as data collection tools. The results of the study showed that there were significant relationships between unidimensional pain stress and disability and negative mood (r(1,167) = 0.33; 0.36, respectively); multidimensional pain stress and disability and negative mood (r(1,167) = 0.51; 0.38, respectively); transactional pain stress and disability, negative mood (r(1,167) = 0.43; 0.37, respectively) and daily activity (r(1,167) = -0.24). The results indicate the significance of new measures in the assessment of pain experience.
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- 2023
8. Üniversite Öğrencilerinde Algılanan Stres, Üstbiliş ve Duygusal Düzenlemeler Arasındaki İlişkinin İncelenmesi
- Author
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Zekeriya TEMİRCAN
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
Students experience stress because of difficult and demanding situations, which are related to metacognitive abilities and emotional control techniques. College students experience negative emotions frequently, which affect their capacity for metacognition. The purpose of the study was to examine the relationship between college students' perceptions of stress, metacognition, and emotional control. 226 college students in all, ranging in age from 18 to 35, participated in the cross-sectional study (M = 24.8, SD = 4.87). Participants completed a sociodemographic form, the Perceived Stress Scale, the Emotional Regulation Questionnaire, and the Metacognitive Awareness Inventory. The study's findings showed that the majority of participants experienced moderate stress (Male= M = 32.4, SD = 5.3, Female= M = 28.7, SD = 4.9), and male students reported less mastery of metacognitive processes than female students. Additionally, a negative link between perceived stress and emotional regulation was discovered, suggesting that a low degree of emotional regulation was associated with a high level of stress. The findings further showed that higher levels of stress were associated with weaker metacognitive capacity and lower use of reappraisal as an emotional regulation method, respectively (r(224)=-.182). These results demonstrated a relationship between perceived stress, metacognitive abilities, and emotional regulation that might have significant consequences for supporting and promoting college student performance.
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- 2023
9. Mediator Roles of Perfectionism and Self-Critical Rumination in the Relationship Between Perceived Maternal Rejection and Orthorexia: A Model Testing in a Female Sample
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Burcu KORKMAZ YAYIN and Ceren CEYLAN ERGUN
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Psychiatry and Mental health ,Biological Psychiatry - Abstract
Orthorexia nervosa (ON) refers to a pathological obsession with healthy eating characterized by a restrictive diet, ritualized eating patterns, and strict avoidance of foods believed to be unhealthy or unclean. On the other hand, healthy orthorexia (HO) is defined as an interest in healthy eating and a tendency to eat healthy foods. This study aimed to investigate the relationships between the ON, HO, maternal rejection, perfectionism, self-critical rumination, and body attitude in the women sample. 445 female students from diverse universities in Turkey was attended to our study. Participants completed questionnaires regarding ON and HO, body attitude, maternal rejection, perfectionism, and self-critical rumination. The results showed that negative body attitudes could not predict both HO (B=-.008, SE=.039, p=.791) and ON (B=.008, SE=.032, p=.835). However, perfectionism and self-critical rumination had mediator roles in the relationship between ON and HO with maternal rejection, despite this relationship was positive for ON (B = .014, Boot SE = .007, 95% Boot CI [.003, .029]), but negative for HO (B = -.023, Boot SE = .010, 95% Boot CI [-.042, -.008]). Not a negative body attitude, but maternal rejection, perfectionism, and self-critical rumination played roles in developing orthorexic tendencies.
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- 2023
10. Comparison of Attachment Styles, Family Functioning and Locus of Control in Individuals with and without Alcohol Use Disorder
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Semiha MENDER, Hande ÇELİKAY, and Buse CİVEK
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Psychiatry and Mental health ,Biological Psychiatry - Abstract
This study aims to examine the variables of attachment styles , family functioning, and locus of control in individuals with and without alcohol use disorder. The 54 participants, including 51 male and 3 females with alcohol use disorder between the ages of 18-60s were chosen from the outpatients of xx service, the attendants of xx meetings, and the people referred by them. The control group consisted of 60 participants who were similar to the study group in terms of age and gender variables, without alcohol use disorder and psychological disorder. Data were collected through a questionnaire including Sociodemographic Data Form, Michigan Alcoholism Screening Test (MAST), Experiences in Close Relationships - Revised (ECR -R), Family Assessment Device (FAD), and Rotter’s Locus of Control Scale (LCS). In the results of the study, it was found that the participants with alcohol use disorder had a significantly higher ECR-R anxiety and avoidance score, and LCS score than the control group. Participants with the alcohol use disorder had a considerably lower FAD score than the control group. Finally, the effects of the applied scales on alcohol addiction are analyzed and it was concluded that the scores of FAD and LCS had a statistically significant effect on alcohol addiction. Accordingly, an increase in the FAD score by one unit reduces the alcohol addiction risk by %95, while an increase in the LCS score by one unit increases the alcohol addiction risk by %31.
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- 2023
11. Attitudes of Individuals with Alcohol and Substance Addiction Towards Violence Against Women
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Hümeyra HANÇER TOK, Makbule TOKUR KESGİN, and Ayşegül KOÇ
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Psychiatry and Mental health ,Biological Psychiatry - Abstract
The aim of this study was to determine the attitudes of alcohol and substance dependent individuals towards violence against women. This cross-sectional study was completed with n=105 patients who were followed up in the Alcohol and Substance Addiction Treatment and Research Center of a state hospital. In this study, personal information form and ISKEBE attitudes towards violence against women scale were used as data collection tools. Among the patients diagnosed with alcohol-substance use disorder, n=53 (60.9%) were between the ages of 18-34 and n=70 (66.7%) were single. Of the patients, n=36 (52.2%) had been exposed to any type of domestic violence. The attitude scores of patients diagnosed with alcohol-substance use disorder towards violence against women were measured as 99.89 ± 22.1. In the current study, patients diagnosed with alcohol-substance use disorder who were male, lived in rural areas, had poor income status and had low educational level were found to have negatively low attitudes towards violence against women. In conclusion of this study, further studies and practices to determine and improve attitudes towards violence against women in patients diagnosed with alcohol-substance use disorder are recommended.
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- 2023
12. Toplum Ruh Sağlığı Merkezlerinde Vaka Yöneticiliği Yapılan Şizofreni Hastaları Daha Mutlu mu?
- Author
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Elif ÖZCAN TOZOĞLU
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
Şizofreni hastaları için iyileşmeden bahsedilirken belirtilerin olmaması ile yetinilmiş ve mutluluk kavramı genelde göz ardı edilmiştir. Çalışmamızda toplum ruh sağlığı merkezi (TRSM) tarafından takip edilip vaka yöneticisi olan şizofreni hastaları ile sadece poliklinik takibi yapılan remisyondaki şizofreni hastalarının mutluluk düzeylerini ve bu mutluluğu etkilediği düşünülen duygu dışavurumu, hastanın algıladığı destek düzeyi ve yaşam niteliğini karşılaştırmayı amaçladık. En az 1 yıldır düzenli TRSM takibi yapılan ve vaka yöneticisi (VY) olan (n:100) ve poliklinik takibi yapılan en az 3 aydır remisyonda olan (n:100) şizofreni hastaları çalışmaya alındı. Her iki gruba Öznel Mutluluk Ölçeği (ÖMÖ), Algılanan Elde Edilebilir Destek Ölçeği (AEEDÖ), Yaşam Niteliği Ölçeği (YNÖ), Duygu Dışavurum Düzeyi Ölçeği (DDDÖ) uygulandı. ÖMÖ, AEEDÖ, DDDÖ, YNÖ puanları VY olan grupta istatistiki olarak anlamlı farklıydı. Duygu Dışavurum Düzeyini gösteren alt ölçekler ile ÖMÖ puanları arasında negatif korelasyon saptandı. YNÖ ve AEEDÖ puanları ile ÖMÖ puanları arasında ise pozitif korelasyon saptandı. VY olması durumunda AEEDÖ puanlarının ÖMÖ puanları üzerinde aracı bir etkisi olduğu; YNÖ puanlarının aracı bir etkisi olmadığı saptandı. DDDÖ alt ölçekleri olan müdahalecilik, duygusal tepki ve hoşgörü/beklenti düzeylerinin ÖMÖ puanları üzerinde aracı bir etkiye sahip olduğu; hastalığa karşı tutum düzeylerinin aracı etkiye sahip olmadığı saptandı. Şizofreni hastaları için iyileşmeden bahsederken genelde mutluluk göz ardı edilen bir kavramdır. Çalışmamızda TRSM hizmeti kapsamındaki vaka yöneticiliğinin etkisini değerlendirdik ve şizofreni hastalarının mutluluğuna olumlu etkisi olduğunu saptadık.
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- 2023
13. Masculinity and Seeking Psychological Help: A Review Based on Social Identity Theory
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Adem KANTAR and İlhan YALÇIN
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Psychiatry and Mental health ,Biological Psychiatry - Abstract
To improve their quality of life and mental health, people need psychological help. Past research revealed that although participants reported low levels of life satisfaction, they were hesitant to seek psychological help. In the literature, this situation has been defined as mental health treatment gap. In this context, research focuses on reducing the treatment gap by identifying factors that facilitate and hinder seeking psychological help. Many studies consistently report that men are more reluctant to seek psychological help than women. Therefore, there is a need for a more detailed examination of the factors that affect men's reluctance to seek psychological help. Based on this fact, the study's primary purpose is to provide enlightening information about why men avoid seeking psychological help and the factors that encourage them to seek help. In this study, masculinity's role in seeking help is emphasized in the context of Social Identity Theory. However, past research findings on situations and contexts in which men are willing to seek psychological help are presented. Practitioners and researchers in the mental health field, such as psychiatrists, psychologists, social workers, and psychological counselors, can learn a lot from the review's opinions on the role of traditional masculine norms in seeking psychological help.
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- 2023
14. İnsan İşleyişini Anlamaya Yönelik Bütünleştirici Bir Bakış Açısı: Pozitif Klinik Psikoloji
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Özlem ÖZTÜRK and Zeynep MAÇKALI
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Psychiatry and Mental health ,Biological Psychiatry - Abstract
The number of studies conducted with a holistic perspective as an alternative to the traditional clinical psychology approach has increased. It is noteworthy that studies examine the effects of positive concepts on human health in addition to discomfort. In this study, it was aimed to examine four concepts that are frequently researched in positive psychology, namely well-being, psychological resilience, hope and coping in an integrative context. Also, it was aimed to give information about the positive clinical psychology approach and the studies which investigate these four positive concepts. Studies were searched through PsycARTICLE, EBSCO and Pubmed electronic databases. Totally 208 studies were reached and 26 articles were included in this review article. As a result, the effective results in treatment of psychological disorders and increase of well-being of an individual with positive psychology interventions suggest that it is important to expand the positive perspective in clinical psychology. It is thought that it may be clinically important that the presence/increase of positive concepts as well as the absence/decrease of psychopathologies should be one of the treatment targets of mental health specialists. It is hoped that adopting an integrative perspective in future studies will enrich empirical research in the field of psychotherapy.
- Published
- 2023
15. Relationship between Alexithymia and Coping Attitudes in Generalized Anxiety Disorder
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Hayriye BAYKAN and Merve ŞAHİN CAN
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Psychiatry and Mental health ,Biological Psychiatry - Abstract
Among anxiety disorders, the incidence of alexithymic features is found in a wide range of 12.5-58%, and it is a personality trait that can also be seen in healthy individuals. Our study investigated the relationship between alexithymic features and coping attitudes in patients with generalized anxiety disorder. Forty patients diagnosed with Generalized Anxiety Disorder and 39 healthy volunteers participated in the study. Participants were divided into groups using the Toronto Alexithymia Scale, and the Hamilton Anxiety Scale and Coping Attitudes Scale were applied to all participants. Nineteen patients with alexithymia and Generalized anxiety disorder, 21 patients with Generalized anxiety disorder without alexithymia, and 39 healthy volunteers participated in this study. Statistically significant differences were observed between the problem-focused coping and emotion-focused coping subscale scores, but there was no difference in dysfunctional coping styles between the three groups. In the correlation analysis performed to determine the relationship between the total alexithymia and Coping attitudes subscale scores, there was a moderate negative correlation between the alexithymia scores and problem-focused (r=-0.442) and emotion-focused coping (r=-0.425) subscale scores. Alexithymia is often accompanied by generalized anxiety disorder and negatively affects coping attitudes.
- Published
- 2023
16. Travma Sonrası Stres Bozukluğunu Açıklayan Bilişsel Modeller ve Travma Mağdurlarında Sık Kullanılan Bilişsel Terapi Yöntemleri
- Author
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Mustafa Kerim ŞİMŞEK
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Psychiatry and Mental health ,Biological Psychiatry - Abstract
Trauma is considered a significant event that causes intense fear and anxiety and frequent avoidance owing to its unfolding and persistence. Post-traumatic stress disorder (PTSD) may develop when the distress and symptoms caused by the development and acute nature of the trauma do not resolve spontaneously over time. Incompatibility with one's existing schemas and the emergence of new nonfunctional schemas are both effective in the development of PTSD. Thus, while working with trauma victims, attempts to restructure the existing traumatic cognitions by doing assessments about traumatic cognitions play an effective role in reinterpreting the traumatic experience. This review study examines the nature of trauma, the expression of trauma according to cognitive therapy, widely recognized cognitive models explaining trauma, and frequently utilized effective cognitive methods for trauma victims. The impact of cognitive processes on the development and continuation of trauma was expressed, and the models of different experts explaining trauma were discussed in detail. Furthermore, considering the contribution of cognitive therapy intervention techniques for PTSD in healthily reevaluating the trauma, cognitive therapy methods that are thought to contribute to both the victim and mental health professionals are included.
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- 2023
17. Şizofreni Hastalarında İşitsel Halüsinasyonların Tedavisinde Avatar Terapi Modeli ve Etik İlkeler
- Author
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Zeynep ÖZEROL and Sezin ANDİÇ
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Psychiatry and Mental health ,Biological Psychiatry - Abstract
Schizophrenia is one of the most debilitating mental disorders. Auditory hallucinations, which are known to be closely related to interpersonal relationships, are the most common type of hallucinations observed in the course of schizophrenia. Virtual reality has been developing in various fields with the development of computerized technologies and has started to appear in the field of clinical psychology in the form of virtual reality therapies. Avatar therapy is among the interpersonal-based virtual reality therapy models that focus on auditory hallucinations among the symptoms of schizophrenia. The aim of avatar therapy is to enable the person to have control over auditory hallucinations. Within the scope of this review study; the past, present and future of schizophrenia treatment, effective intervention methods in the treatment of schizophrenia, virtual reality therapy, the main outlines of the avatar therapy model, the effectiveness studies of avatar therapy and ethical issues were discussed. The results of the research on the effectiveness of avatar therapy reveal the need for further research in this field.
- Published
- 2023
18. Bir Öz Bakım Eksikliği Sendromu: Öz-İhmal
- Author
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Cansu GÜLER and Esra ENGİN
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Psychiatry and Mental health ,Biological Psychiatry - Abstract
Self-neglect is the individual's failure to show the necessary attention and care in his own care. Self-neglect manifests itself as non-adherence to treatment, failure to maintain personal and environmental hygiene, and maladaptive health behaviours. At the global level, although self-neglect is frequently seen especially in the elderly population, it is seen in all age groups and especially in disease groups where disability is in question and their caregivers. Self-neglect, which is divided into two categories as intentional and unintentional, is an important cause of morbidity and mortality. Failure to maintain accepted self-care standards caused by self-neglect threatens not only personal but also public health and well-being and increases the burden of health services and health care costs. Self-neglect is difficult to detect because individuals are isolated and do not have the risk of directly harming themselves. Due to reasons such as non-compliance with current treatment, ineffective health management, these individuals' access to the health system is disrupted and the diagnosis and intervention of self-neglect is delayed because they only apply to health services in emergencies. Health professionals working in the field of public health and mental health, especially community mental health professionals, have important responsibilities for the diagnosis and intervention of self-neglect.
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- 2023
19. Prospective and Retrospective Timing Processes: Theories and Methods
- Author
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Reyhan ÜNVER
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
We experience a flow of time in everyday life. However, according to modern physics, time does not flow. In the psychology and neuroscience literature, different models and explanations have been made to try to answer the question of what time is besides an illusion of flow and to figure out how time is perceived. Different methods have also been used to learn how time is handled and to test how accurate these models are. People process time in two ways: implicitly and explicitly. We are talking about explicit timing when estimating the time interval length. Another distinction, according to the measurement method of time perception paradigms, is between prospective and retrospective time estimations. Although there are theorists who claim that these two methods involve similar cognitive processes, it is thought that different cognitive processes serve to experience and remember a time, depending on whether time perception is measured by the prospective or retrospective time estimation methods. This brings to mind different method-dependent constraints and advantages. As with any other kind of perception study, the method chosen for time perception research should fit the question being asked. This review presents a selective review of time perception studies to make it easier for a researcher planning to study time perception to choose the appropriate method for the study question. The time perception processes and related evidence were examined using prospective and retrospective time estimation measurement methods. But it's important to note that the time perception models and methods talked about in this review are only a small part of a very large field.
- Published
- 2023
20. Depresyon Atak Sayısının Depresyon Şiddeti, Tedavi Uyumu, Stres, Kişilik, Yürütücü İşlevler ve Karar Verme ile İlişkisi
- Author
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Tuğba ÇEBİOĞLU and Hatice KAFADAR
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
Major depressive disorder (MDD) is a psychiatric disorder that significantly affects the world population. The aim of this study was to investigate the relationship between the number of episodes and severity of depression, treatment adherence, perceived stress, personality, executive functions and decision making in MDD patients. Measurement tools including Beck Depression Inventory (BDI), Morisky Medication Adherence Scale (MMAS), Perceived Stress Scale (ASO-14), Temperament and Personality Inventory-Revised Form (TCI-R), Wechsler Memory Scale-III/Letter-Number Sequence Subtest (HSD), Wisconsin Card Sorting Test (WCST), Stroop Test TBAG Form (STR) and Iowa Gambling Taskt (IGT) were used in the study. The findings of the study showed that the severity of depression in MDD was not related to the number of episodes (r=-0.051, p>0.05) and treatment compliance (r=-0.082, p>0.05), but there was a significant relationship between the number of episodes and treatment compliance (r=-0.880, p
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- 2023
21. Yeme Bozukluklarında İntihar Davranışı
- Author
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Hatice Ayça KALOĞLU and Cicek HOCAOGLU
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
Many studies have shown that people with eating disorders have higher rates of suicidal ideation, suicide attempts, and completed suicide than the general population. One of the diseases with the highest suicide rate among psychiatric disorders is anorexia nervosa. Some hypotheses have been proposed to explain possible causes of increased suicidal behavior in eating disorders. Some conditions common to eating disorders and suicidal behavior, such as dissatisfaction with the body and interoceptive deficits, have been cited. It has been conclusively shown that psychiatric comorbidity, especially the co-diagnosis of depression, increases the risk of suicide in patients with eating disorders. However, increased suicidal behavior in eating disorders cannot be explained by comorbidity alone. The interpersonal psychological theory of suicide (IPTS), developed by Joiner, aims to understand why people commit suicide and to explain the differences in individual suicidal behavior. Some researchers have thought that the increased suicidal behavior of people with eating disorders, especially anorexia nervosa patients, is expected from the perspective of IPTS. The compensatory behaviors of patients with eating disorders, such as vomiting or chronic restrictive food intake, are painful and challenging actions for the body. It can be considered that repeated encounters with painful and challenging experiences form a habit in the individual and reduce pain avoidance. When viewed from the IPTS perspective, decreased pain avoidance may explain the increased suicide attempts and completed suicides of individuals. Clinicians working with eating disorder patients must conduct regular and comprehensive assessments of suicide. Comorbidities such as major depression, anxiety disorder, and substance-use disorder should not be overlooked in patients with eating disorders and should be taken seriously.
- Published
- 2023
22. 'Hachiko: Bir Köpeğin Hikayesi' Filminin Hayvanlara Yönelik Empati ve Hayvanlarla Dayanışma Kavramları Açısından Değerlendirilmesi
- Author
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Nur OKUTAN
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
The aim of this study was to analyze the movie "Hachiko: A Dog's Story" in terms of empathy and solidarity with animals. For this purpose, the scenes in the movie were interpreted on the basis of empathic reactions towards animals (cognitive and affective; self/other-oriented) and solidarity with animals (emotions and behaviors such as attachment, belonging, intimacy, and cooperation). The movie is about the attachment between a dog and a human, and it encourages the viewers to understand this attachment. In order for this to happen, audiences should be able to empathize with the protagonist of the movie, Hachi. Through the analysis of the movie, it becomes clear that empathy with animals is depicted in scenes where efforts are made to understand the protagonist's fear, joy, or expectations (self/other-oriented cognitive empathic responses) as well as in scenes where the desire to do something for the protagonist is shown (other-oriented emotional empathic responses). Solidarity with animals is depicted in scenes that include emotions and behaviors such as sharing (time, happiness, sorrow, “bread”), support (helping, assuming care, etc.), and intimacy (desire to be together). Additionally, the movie directs viewers towards a dog's emotions such as joy, loyalty, sorrow, separation, and longing in many scenes..
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- 2023
23. Otizm Spektrum Bozukluklarında Glia Hücrelerinin Rolü
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Melis Elif ELÇİ, Miraç Barış USTA, and Koray KARABEKİROĞLU
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Psychiatry and Mental health ,Biological Psychiatry - Abstract
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with an increasing frequency, manifested by functional disorders in social communication and social interaction, limited interests, and repetitive behaviors. The etiology of autism spectrum disorder has not yet been fully elucidated and there are many areas that need further study. Increasing studies have shown that disruptions in synaptic functions are critical in the onset of ASD. Glial cells have a role in the regulation of synaptic functions. In ASD, changes are seen in the number of neurons and glia cells in the affected cerebral cortex, and these changes cause dysregulation in synaptic functions and affect behaviors. Studies provide information about the role of glia cells in the pathophysiology of ASD, but more data is needed on the relationship between ASD and glia cells. In this review, the importance of glial cells in the etiopathogenesis of ASD and studies will be discussed.
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- 2023
24. Romantik İlişki İçerikli Obsesif Kompulsif Bozukluk: Sistematik Derleme
- Author
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Melis MISIRLI and Gamze KARADAYI KAYNAK
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
Obsessive Compulsive Disorder (OCD) is a disorder characterized by obsessions and compulsions and negatively affects the functionality of individuals. OCD symptoms with romantic relationship content have been investigated in the literature for the last 10 years. OCD symptoms with romantic relationship content are divided into two types: relationship-centered and partner-focused. The aim of this systematic review was to examine the relationship between OCD symptoms with romantic relationship content and individual and relational variables. Studies in the literature were reviewed in detail in order to evaluate the results regarding the relationship between OCD symptoms in romantic relationships and individual and relational factors. In the national and international literature, no systematic review study on this subject was found. Accordingly, studies published between 2012 and 2022 in internationally accepted electronic databases using the terms "relationship obsessive compulsive disorder", "relationship centered obsessive compulsive symptoms" and "partner focused obsessive compulsive symptoms" were reviewed. As a result of the search, according to the inclusion criteria, 12 empirical studies on the relationship between OCD in romantic relationships and individual and relational variables with full-text access and written in English were analyzed. The methodological characteristics and results of the 12 included studies are presented in this systematic review study. The results of the studies suggest that symptoms related to romantic relationships negatively affect the functioning of individuals similar to OCD. When the variables associated with obsessive-compulsive symptoms in romantic relationships are analyzed in individual and relational context, they are related to many factors such as psychopathologies, attachment styles, self and relationship satisfaction. In this context, there is a need for empirical studies carried out with clinical samples, exploring the effectiveness of psychotherapy and cross-cultural studies on obsessive-compulsive symptoms related to romantic relationships. Keywords
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- 2023
25. Özgül Fobilerde Sanal Gerçeklik ile Maruz Bırakma Terapisinin Etkinliği: Sistematik Bir Gözden Geçirme
- Author
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Merve DEMİR and Tolga KÖSKÜN
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
Specific phobia is defined as a notable and continuous fear of a certain object or a situation that particularly impairs daily life and functioning. It is also one of the most common psychological disorders. Exposure-based interventions are commonly used in the treatment of specific phobias. However, some limitations of the standard methods require the need for alternative approaches. In light of this, the use of virtual reality technology in psychotherapy has become increasingly widespread in recent years and is now integrated with exposure therapy. Virtual reality provides real-time interaction using the computer-generated three-dimensional environment via variety oftechnological tools. Applications of virtual reality in exposure therapy have proven to be an important intervention method, especially in the psychopathologies such as specific phobias. In this study, virtual reality exposure therapy for the treatment of specific phobias is systematically reviewed. Inclusion criteria were taken into account in the scanning performed in APA (PsycINFO), EBSCO, PubMed, Scopus, Web of Science, Science Direct, Ulakbim ve TRDizin databses following the PRISMA method. Following that, ten randomized controlled trials, which included adult participants meeting the diagnostic criteria for specific phobia, examined the efficacy of virtual reality and exposure therapy compared to the control group, and the ones with full text could be accessed, were included in this systematic review. The included studies were evaluated in terms of sample attributes, primary measurement tools, research design, characteristics of the intervention and its efficacy. In general, the findings indicate the efficacy of virtual reality exposure therapy in reducing specific phobia symptoms. Follow-up studies support the long-term maintenance of the results.
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- 2023
26. Parent-Child Interaction Therapy
- Author
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Sümeyye ULAŞ, İsmail SEÇER, and İsmail AY
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
Parent-child interaction therapy is a parent-mediated therapy approach that focuses on solving internalization-externalization problems observed in children aged 2-7. The approach based on parenting styles, attachment theory, behavioral theory, and social learning theories aims to teach play therapy skills to parents. In this direction, each stage was organized as teaching and coaching sessions in an approach that included two phases: a child-directed interaction phase and parent-directed interaction. The first stage, which is the child-directed stage, it is aimed to developing a sincere and warm relationship between the parent and the child by following the child's lead.. In the second phase, the parent-directed interaction phase, effective discipline methods are taught to parents and coached at the point of use, depending on the goal of increasing their child's adaptation skills. Therapy is not time-limited and is performance-oriented. In this study, the general characteristics of parent-child interaction therapy, its historical development, theoretical foundations, the structure of therapy sessions, the intervention process, and parent-child interaction therapy research are included. As a result of the review, depending on the international literature, can be said to be parent-child interaction therapy is an early-term, parent-oriented and evidence-based approach that is effective on early childhood compliance and behavior problems, including children with neurodevelopmental problems, parenting stress, parental efficacy perception, and family harmony.
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- 2023
27. The Concept of Parental Praise in Parenting
- Author
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Gülçin KARADENİZ
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
Praise is stated as a good performance resource that can increase the individual's sense of competence and motivate their new learning. When the literature is examined, the importance of communication with the child in parenting is emphasized, especially the power of the words used by the parents. Parental praise is expressed as parents' repetition of the desired behaviors in children and giving feedback that will make them feel warm and sensitive with their words and behaviors in order to indicate the satisfaction felt towards them. Studies emphasize that parental praise is an important method in child development and a method that parents use very often. It is reported that many parents prefer to use praise as a tool to build self-confidence in their child. In terms of positive discipline, it is assumed that praise creates a reward value as a result of operant conditioning and can affect behavioral acquisition in the child's development. The type of parental praise plays an important role in how children form their self-image. It is in these early relationships that children first begin to feel capable, competent, and loved. Although praise is expressed as a source of motivation when it cannot be used beneficially, it can become harmful to the child when used incorrectly or excessively. At this point, the content of the praise is important. In this study, the concept of parental praise is discussed, the content of praise, which is seen as a reference to motivation, is examined and its benefits for child development are tried to be explained.
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- 2023
28. Otizm Spektrum Bozukluklarında Mitokondriyal Disfonksiyon ve mTOR
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Ezgi SELAMET and Miraç Barış USTA
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
Autism spectrum disorders (ASD) are neurodevelopmental diseases that manifest themselves at early ages as insufficient social and communicative skills, repetitive sensory-motor behaviors and restricted interests, and peculiar combinations of these traits. Autism prevalence in wealthy nations is currently rising. Due to increasing numbers of diagnosis, studies on the genetic background of autism have gained momentum recently. Especially the research on mitochondrial dysfunction and mammalian target of rapamycin (mTOR) is important in that it might provide a great contribution to the ASD field for new treatment resources. .
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- 2023
29. Sprouting Tree for Physiological Stress Assessment Using Fuzzy Petri Net
- Author
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Richa Gupta, Parul Agarwal, and M. Afshar Alam
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Psychiatry and Mental health - Abstract
Background: Stressors have a huge impact on one’s well-being. They affect individual’s mental and physical health, if untreated. The response to these stresses is termed as a stress response. Based on the type and severity of the stimulus, stress can affect the various actions and functioning of the body. This explains how important it becomes to detect the level of stress and treat it well. The best treatment for stress is to identify the factors causing stress and eliminate them in the initial stage. Various methods have been proposed to detect the level of stress. One of the common methods is by using wearable devices to capture EEG signals and use various proposed algorithms to detect the level of stress. However, there are cases where stress cannot be captured by non-invasive technologies. Besides, these technologies cannot determine the stress-causing factors. This paper proposes a methodology to cater to such cases and identify the factors causing stress in the patient. It can also act as a front line methodology to detect if the candidate is suffering from anxiety or stress. The use of fuzzy logic in various healthcare areas has become very evident. This is because it deals with a range of values. While, Petri nets is a network where the arc runs from place to transition and not between places and transitions. It is the best model to use in dynamic and concurrent activities of the system. Thus, a combination of these two logics can provide an extremely competent basis for the implementation of computing reasoning processes and the modeling of systems with uncertainty. Thus, Fuzzy Petri Nets (FPN) have been proposed. This paper proposes the use of FPN in designing a methodology for factors responsible for causing stress and advancing the level of stress in the patient. The methodology is developed by observing the process of food transfer in plants. The authors have also discussed afferent and efferent stress paths. Method: The methodology proposed in this paper uses Fuzzy Petri Net. The algorithm designed in this paper has been named as the Sprouting tree algorithm by the authors. Designing the fault tree is the first and very important step for the correct determination of the level of the stress. The score generated using the Hamilton scale is fed as input to the AND/OR gate system to receive the value of stressor, and thus, drawing a fault tree. The transformation rules are applied to convert the fault tree into the FPN. Then, we derive production rules and reachability matrix. These rules help in normalizing the value obtained via fault tree so that they lie in the range of fuzzy logic. FPN calculates the certainty factor (CF), which represents the state of stress in an individual. Therefore, the values obtained from FPN will finally build a tree, which is named as Sprouting tree. Conclusions: The methodology proposed in this paper is absolutely new to detecting the stress. The future of this work is to observe the accuracy of the proposed algorithm by implementing it with real data, which is under process.
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- 2023
30. Oral Disintegrating Tablets of Proton Pump Inhibitors for Chronic Gastroesophageal Reflux Disease: An Update
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Juber Akhtar, Avani Gupta, KC Rastogi, null Badruddeen, Mohammad Irfan Khan, and Mohammad Ahmad
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Psychiatry and Mental health - Abstract
Abstract: Oral disintegrating tablets (ODT) offer an attractive choice for Gastroesophageal Reflux Disease (GERD) patients suffering from dysphagia. In chronic condition, GERD patient suffers from severe erosive esophagitis. Thus patients feel difficulty and pain during swallowing, which results in patient in-compliance toward medication of tablets or capsules- especially in geriatrics and pediatric patients. These symptoms of GERD patients have attracted the formulation scientists in improving the formulation methodology for such patients. Orally disintegrating tablets could increase the therapeutic impact and drug compliance in these patients. The aim of this compilation is to provide a more convenient way to develop an oral disintegrating drug delivery system of proton pump inhibitors in patients suffering from odynophagia, associated with chronic Gastroesophageal Reflux Disease (GERD). Oral disintegrating tablets (ODT), when placed on the tongue, can quickly disintegrate and release the medicament. It later dissolves or disperses in saliva without any additional water. The saliva containing drug can easily be swallowed and descends into the stomach leading to maximum absorption from the mouth, throat, and upper esophagus. The patient compliance and bio-availability of Oral disintegrating tablets (ODT) are high compared to other conventional tablets.
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- 2023
31. Chimeric Antigen Receptor T-cell Therapy in Cancer: A Critical Review
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Nitesh Kumar, Ravikant Sharma, Lalitha Suravarjhula, Madhuparna Banerjee, and Gautam Kumar
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Psychiatry and Mental health - Abstract
Abstract: Targeted cancer therapy acts on targeted molecules, is less toxic to normal cells, and acts more specifically on cancer cells. The two primary strategies for preventing malignancy growth are the blocking of T-cell repression signals or forwarding of T-cell to tumor target with both T and tumor-specific antibodies. The CAR comprises three domains, the extracellular antigen recognition domain and the intracellular T-cell signaling domain, which participate in activating T-cells. The two most common adverse effects of CAR T-cell treatment are cytokine release syndrome (CRS) and cell-associated neurotoxicity syndrome (CANS). The adaptability of intracellular signaling domains inside CARs allows the cell to counterbalance the downregulation of costimulatory molecules produced by tumor cells, either indirectly or directly. The major disadvantage of CAR-T cell therapy is off-target toxicity. Treatment with CARs expressing CD3, CD123, Lewis Y, CLL-1, CD44v6, FLT3, and folate receptors showed promising results in preclinical models of acute myeloid leukemia (AML). A recent study has revealed that B7-H3 CART cells exhibit significant anticancer efficacy in a variety of solid tumor preclinical models, including PDAC, ovarian cancer, neuroblastoma, and various pediatric malignancies. The notion of SUPRA CAR, with its unique capacity to alter targets without the need to re-engineer, is a recent innovation in CAR. Given the importance of NK cells in tumor development and metastatic defence, NK cell-based immunotherapies, including adoptive transfer of NK cells, have garnered a lot of interest. With the advancement of improved cellular manufacturing methods, novel cellular engineering strategies, precision genome editing technologies, and combination therapy approaches, we firmly believe that CAR-T cells will soon become an off-the-shelf, cost-effective, and potentially curative therapy for oncogenesis.
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- 2023
32. Systematic Review and Meta-analysis of the Relationship Between Proton Pump Inhibitors and Esophageal Adenocarcinoma
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Saeid Soureshjan-Heidari, Mohammad Darvishi, and Matin Bidares
- Subjects
Psychiatry and Mental health - Abstract
Introduction and Aim: Esophageal adenocarcinoma (EAC) mortality continues to increase across the world. This meta-analysis was aimed to investigate the relationship between proton pump inhibitors (PPIs) and the risk of EAC. Methods: This meta-analysis was done as per the PRISMA checklist using relevant keywords. To this end, an extensive search was done on 29/6/2022 in EMBASE, Web of Science (ISI), PubMed, and Scopus. In this study, 95% confidence interval (CI) and standardized mean difference (SMD) were used to estimate the overall effect size. Analysis of the odds ratio (OR) for EAC was done using a random effects model. Results: A total of 20 studies were included in the review. Compared to the group that received PPIs, the OR of EAC in the recipients of the PPIs group was obtained at 0.67 (95% CI = 0.39-1.29, P = 0.240). The meta-regression, including year, follow-up time, study design, sample size, quality of the study, study period, and geographical location, demonstrated no source of heterogeneity (P > 0.10). Conclusion: No significant relationship was found between PPIs use and the risk of EAC. Accordingly, PPIs do not have a protective or risk factor effect on EAC.
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- 2023
33. Mental Health Needs in COVID and Post-COVID Era-How Far Can Telepsychiatry Address the Challenges?
- Author
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Udayan Bhaumik
- Subjects
Psychiatry and Mental health - Abstract
Abstract: The coronavirus pandemic of 2019 has resulted in extensive social regulations and affected many aspects of life. It has led to significant stress and adversely impacted mental health across the globe. The virus has been found to directly increase neuropsychiatric sequelae in those affected. Various psychosocial factors have also increased the incidence and prevalence of mental health problems worldwide. There was a need for a ramp-up of psychiatric services to support individuals in such a situation. Even after the pandemic, there is a need for improving access to mental health services for the mentally ill as well as those affected by the regulations brought about to tackle the pandemic. Telepsychiatric services are in place throughout the world in different forms and are the answer to bridging the mental health gap during and in the aftermath of the pandemic. Hence, it is important to continue developing and enhancing tele psychiatric services in different countries for supporting and treating individuals affected by the pandemic.
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- 2023
34. Quality by Design-based RP-HPLC Method for Estimation of Curcumin in Rat Plasma and Fecal Microbiota Extract-based Solid Self-nano Emulsifying Drug Delivery System
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Sachin Kumar Singh, Leander Corrie, Monica Gulati, Jaskiran Kaur, Ankit Awasthi, Sukriti Vishwas, Arya Kadukkattil Ramanunny, Rubiya Khursheed, Kamal Dua, and Dinesh Kumar Chellappan
- Subjects
Psychiatry and Mental health - Abstract
Background: Curcumin (CRM) is known to possess various therapeutic properties, such as anti-inflammatory and antidiabetic properties, and is, therefore, considered to be an effective therapeutic. Objective: A sensitive method for the estimation of CRM in plasma, as well as fecal matter-based solid self-nano emulsifying drug delivery system (S-SNEDDS), has been reported for the first time. Methods: A bioanalytical method was optimized using Box-Behnken Design having 13 runs and 3 responses. The optimized method was developed using methanol and water (70:30 v/v) with a flow rate of 1 mL/min. Quercetin was used as an internal standard. A specificity test was also performed for the developed CRM solid self-nano emulsifying drug delivery system. Results: The retention time of CRM was found to be 14.18 minutes. The developed method was validated and found to be linear in the range of 50-250 ng/mL with an R2 of 0.999. Accuracy studies indicated that CRM had a percentage recovery of less than 105% and more than 95%, respectively. Precision studies were carried out for inter, intraday, and inter-analyst precision, and the %RSD was found to be less than 2%. The limit of detection (LOD) and limit of quantification (LOQ) were found to be 3.37 ng/mL and 10.23 ng/mL, respectively. Stability studies for shortterm, long term and freeze-thaw cycles showed a %RSD of less than 2%, indicating the stability of CRM in the plasma matrix. Moreover, the blank fecal microbiota extract slurry did not show any peak at the retention time of CRM in a CRM-loaded solid nanoemulsifying drug delivery system containing fecal microbiota extract indicating its specificity. Conclusion: Hence, the developed method can have clinical implications as it helps estimate CRM in blood samples and also provides a simple and sensitive method for the estimation of plant-based flavonoids along with fecal microbiota extract formulations.
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- 2023
35. Prevalence of Comorbidities of Psychotic Disorders in Patients with Substance Use Disorders in Iran Psychiatric Hospital in Tehran, Iran
- Author
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Afsaneh Aminpour, Shiva Soraya, and Hamidreza Ahmad Khaniha
- Subjects
Psychiatry and Mental health - Abstract
Background: Substance use disorders are highly prevalent among psychotic patients and are associated with poorer clinical outcomes. Objective: This study aimed to investigate the prevalence of psychotic disorders in substance users and the epidemiological features of this population. Material & Methods: In a cross-sectional study, we investigated 455 outpatient and inpatient participants with SUD referred to the Iran psychiatric hospital from April, 2020, to March, 2021. All participants were substance users, referred to Iran psychiatric center to follow up on their comorbidities and psychiatric disorders. The Structured Clinical Interview for DSM-5 (SCID) was used for psychotic disorders and substance use disorder diagnoses. Finally, gathered data were analyzed by SPSS-25. Results: A total of 455 patients were involved in the study. The mean age was 34.66 years, of which 89.7% were men. The most common main substances include methamphetamine (39.1%) and heroin (27%). The prevalence of psychotic disorder was 36.7%, and the most common type was substance-induced psychotic disorder (26.4%) and schizophrenia (8.4%). There was a significant association between methamphetamine and opium use and the presence of substance-induced psychotic disorder and schizophrenia, respectively (p< 0.001). Conclusion: The most common type of substance use was methamphetamine, and the most common type of psychotic disorder was substance-induced psychotic disorder. There was a significant association between methamphetamine and opium use and the presence of substance- induced psychotic disorder and schizophrenia, respectively. It should be noted that this was a sample of individuals hospitalized for substance abuse. It was not a general population sample and was very biased toward substance use.
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- 2023
36. Biomarkers For the Diagnosis of Depression: Recent Updates
- Author
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Kedar S. Prabhavalkar and Mikhil Santosh Kore
- Subjects
Psychiatry and Mental health - Abstract
Abstract: Depression, or major depressive disorder, is a mental illness that significantly affects psychosocial functioning and reduces the quality of one’s life. The annual incidence of depression throughout the globe is around 6%. The disorder should be diagnosed at a particular stage for the treatment to be designed. Biomarkers can help to do so with objective pieces of evidence. Various biomarkers like Imaging biomarkers, Molecular biomarkers, Transcriptomic biomarkers, Genetic biomarkers, Neuroendocrine, and Inflammatory biomarkers can be used to diagnose depression. The use of digital sensors has also been reported recently for the determination of depression. This review summarizes various biomarkers to diagnose depression. Further recent updates and related clinical trials are included.
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- 2023
37. Thioredoxin Interacting Protein Inhibitors in Diabetes Mellitus: A Critical Review
- Author
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Selvaraj Jubie, Ayushi Kar, Balamurugan Paramasivam, Darshini Jayakumar, and Akey Krishna Swaroop
- Subjects
Psychiatry and Mental health - Abstract
Abstract: Diabetes Mellitus (DM) is one of the highest contributors to global mortality, exceeding numbers of even the three major infectious diseases in the world, namely Tuberculosis, HIV AIDS, and Malaria. DM is characterised by increased serum levels of glucose caused by a loss of beta cells of the pancreatic islets, responsible for the secretion of insulin. Upon accumulation of data via a wide array of literature surveys, it has been found that Thioredoxin Interacting Protein (TXNIP) presents itself as a vital factor in controlling the production and loss of beta islet cells. TXNIP inhibits the action of the Thioredoxin (TRX) protein found in the beta cells thereby rendering it ineffective in maintaining the cellular redox balance causing oxidative stress and subsequent consequences ultimately leading to aggravation of the disease. TRX exists in the form of two isoforms - TRX1, which is located in the cytosol and at times translocates to the nucleus, and TRX2, which is located in the nucleus. TRX is responsible for the maintenance of the normal cellular redox balance by reducing the oxidised proteins formed by the Reactive Oxygen Species (ROS) with the help of NADPH dependent TRX Reductase enzyme. This proves to be essential in the pathogenesis of Diabetes Mellitus as the beta cells of the pancreatic islets lack a sufficient amount of antioxidant systems. Thus, inhibition of TXNIP has become essential in the survival of beta cells, not only enhancing insulin secretion and sensitivity but also alleviating the diseases associated with Diabetes. Hence, TXNIP is discovered to be a unique therapeutic target in the management of DM.
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- 2023
38. Is Child Maltreatment a Risk Factor for Borderline Personality Disorder? A Systematic Review of Prospective Longitudinal Studies
- Author
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Julien Morizot and Marie-Sarah Girard
- Subjects
Psychiatry and Mental health - Abstract
Background: Borderline personality disorder (BPD) is a clinical condition associated with numerous individual and collective negative consequences. According to several etiological theories and retrospective research, child maltreatment (CM) may be considered a central factor explaining BPD development. Objectives: In order to verify this hypothesis, a systematic review of prospective longitudinal studies was conducted. Methods: Following searches in five electronic databases, 19 articles that examined the relationship between CM (i.e., physical, sexual and emotional abuse; physical and emotional neglect) and BPD (i.e., diagnosis or severity score) were selected. Results: Overall, the results only partly confirm the hypothesis that CM is a risk factor for BPD. Evidence for a prospective relationship between CM and later BPD is stronger in studies using a symptom count compared to a categorical diagnosis. However, the small number of studies precludes assessing the differential impacts between CM types and BPD. Conclusion: Available prospective longitudinal studies do not unequivocally support the idea that CM is a robust risk factor for BPD. Future research needs are discussed.
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- 2023
39. Medicinal Importance, Pharmacological Activity and Analytical Aspects of Flavonoid ‘Irisflorentin’ from Belamcanda chinensis (L.) DC
- Author
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Dinesh Kumar Patel
- Subjects
Psychiatry and Mental health - Abstract
Background: Flavonoids are an important class of phytochemicals found to be present in plants and their derived products. Belamcanda chinensis (L.) DC has been used in Traditional Chinese medicine for multiple therapeutic purposes for a very long time. Belamcanda chinensis have been reported to have antipyretic, antidote, expectorant, antiphlogistic, and analgesic activity in the scientific fields. Scientific information on irisflorentin for its medicinal importance and pharmacological activity has been collected through electronic search engines, including Science Direct, Google, Google Scholar, PubMed, and Scopus, and analyzed in the present investigation in order to know the biological potential of irisflorentin. However, analytical aspects of irisflorentin are also discussed in the present work. Further detailed pharmacological activity data of irisflorentin have been collected and analyzed in the present work in order to know the therapeutic potential of irisflorentin in medicine. Scientific data analysis of different research work signified the biological importance and therapeutic benefit of Belamcanda chinensis and irisflorentin in medicine. Scientific data analysis revealed the biological effectiveness of irisflorentin against Parkinson's disease, inflammation, cancer, and brain disorders. Further scientific data analysis also signified the biological potential of irisflorentin for its α-glucosidase inhibitory potential and immunotherapeutic adjuvant in medicine. Metabolism and pharmacokinetic parameters have also been discussed in the present work. Analytical data showed the importance of various analytical methods for separation, identification and estimation of irisflorentin in different biological samples. Scientific data analysis of various research works signified the biological potential and therapeutic effectiveness of irisflorentin in medicine. However, clinical data of irisflorentin should be also investigated in order to know their pharmacokinetic parameters and safety issue in medicine. Results: Scientific data analysis of different research work signified the biological importance and therapeutic benefit of Belamcanda chinensis and irisflorentin in medicine. Scientific data analysis revealed the biological effectiveness of irisflorentin against Parkinson's disease, inflammation, cancer, and brain disorders. Further scientific data analysis also signified the biological potential of irisflorentin for its α-glucosidase inhibitory potential and immunotherapeutic adjuvant in medicine. Metabolism and pharmacokinetic parameters have also been discussed in the present work. Analytical data showed the importance of various analytical methods for separation, identification and estimation of irisflorentin in different biological samples.
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- 2023
40. Linking Social Anxiety and Depression: The Role of Metacognitive Beliefs and Anhedonia
- Author
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Aditi Rai, Usha Barahmand, Amisha Tewari, Kayla Castellanos, Ezra Hermann, and Sarah Kopyto
- Subjects
Psychiatry and Mental health - Abstract
Aim and background: This study aims to examine mechanisms that may account for the comorbidity between social anxiety and depression. Objective: We hypothesized that maladaptive metacognitions and anhedonia would serially mediate the link between social anxiety and depression. Method: We tested this notion by collecting data from 208 international, English speaking participants ranging from the ages of 18 to 65 years old using the Social Interaction Anxiety Scale (SIAS), Self-Assessment Anhedonia Scale (SAAS), Patient’s Health Questionnaire-9 (PHQ-9), and Metacognition Questionnaire (MCQ-30). Results and Discussion: The results show a significant serial mediation effect from social anxiety via beliefs about uncontrollability and danger and anhedonia to depression, with the pathway from social anxiety via reduced beliefs in cognitive confidence and anhedonia to depression not being significant. Furthermore, a direct path from social anxiety to depression was also significant. Conclusions: Findings provide support for both the tripartite model and the self-regulatory executive function model of anxiety and depression. While the findings imply the contributions of other mediating variables, they also indicate that metacognitive therapy with additional focus on anhedonia could be effective in preventing the development of depression.
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- 2023
41. Autonomy and (In)Capacity to Consent in Adolescent Substance Use Treatment and Care
- Author
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Trevor Goodyear, Emily Jenkins, Rod Knight, Kali-olt Sedgemore, Melissa White, Tania Culham, and Danya Fast
- Subjects
Psychiatry and Mental health ,Informed Consent ,Adolescent ,Substance-Related Disorders ,Personal Autonomy ,Pediatrics, Perinatology and Child Health ,Public Health, Environmental and Occupational Health ,Humans - Published
- 2024
- Full Text
- View/download PDF
42. Facing Uncertainty: A Comparison of Hierarchical and Variable Exposure Interventions for Contamination Fear
- Author
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Kelly A. Knowles, Sarah C. Jessup, and Bunmi O. Olatunji
- Subjects
Psychiatry and Mental health ,Clinical Psychology - Abstract
Consistent with the inhibitory retrieval approach, one proposed modification to improve the effectiveness of exposure-based interventions is to maximize variability by not proceeding linearly up an exposure hierarchy. Accordingly, the present study compares hierarchical and variable exposure interventions for contamination-fearful individuals and examines the role of uncertainty to predict intervention outcomes. Participants (
- Published
- 2024
43. A closer look at homework compliance in behavior therapy for bulimia nervosa: does homework compliance in between-session period prospectively predict session-by-session change in bulimia symptoms?
- Author
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Paakhi Srivastava, Megan N. Parker, Emily K. Presseller, Olivia B. Wons, Kelsey E. Clark, and Adrienne S. Juarascio
- Subjects
Psychiatry and Mental health ,Clinical Psychology ,General Medicine - Abstract
Homework assignments are considered key components of behavioral treatments for bulimia nervosa (BN), but little is known about whether homework compliance predicts BN symptom improvement. The present study is the first to examine whether session-by-session change in homework compliance predicts session-by-session changes in BN symptoms during behavioral treatment.Patients with BN-spectrum eating disorders (Significant between-persons effects of self-monitoring and behavioral homework compliance were identified, such that patients with greater compliance in the past week experienced greater reductions in binge eating and purging the following week. There were significant within-persons effects of self-monitoring compliance on binge eating and behavioral homework compliance on restrictive eating, binge eating, and purging, such that greater than one's usual compliance predicted greater improvements in BN symptoms the following week. No significant effects of written homework compliance were identified.Compliance with self-monitoring and behavioral homework predict improvements in BN symptoms during behavioral treatment. These findings reinforce the importance of self-monitoring and behavioral homework compliance as drivers of change during treatment for BN.
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- 2024
44. Anxiety in Children and Adolescents in the Covid-19 Pandemic: A Systematic Review
- Author
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Makbule TOKUR KESGİN and Hümeyra HANÇER TOK
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
The aim of this study was; to define the anxiety and anxiety-related factors experienced by children/adolescents during the Covid-19 pandemic on a global scale. Study data were collected between 15.04.2021 and 30.04.2021 by using keywords (child, children, adolescents, adolescents, mental health, anxiety, anxiety and stress) in Turkish and English. The data sources of this study are PubMed, Web of Science, and Google Scholar t. As a result of the evaluations, a total of n=6185 articles were reached from all databases. After the evaluation of the full texts, the study was completed with n=31 articles. Eleven of the articles evaluated in this study were published in China. The anxiety prevalence of children and adolescents varies between 1.84-45.0%. As a result of the evaluated studies; It has been observed that women, those with chronic-psychiatric diseases, those who are older, separated from family members, migrant children and adolescents are more likely to experience anxiety. Some of the anxiety symptoms of children and adolescents are nervousness, irritability, anxiety, and suicidal ideation. In conclusion, anxiety levels and anxiety-related factors of children and adolescents living in various countries of the world during the Covid-19 pandemic were determined.
- Published
- 2023
45. Reflections of Emotions on Daily Life: Functionality of Positive Emotions
- Author
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Aslı KARTOL
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
People by nature tend to experience more positive emotions and less negative emotions. For centuries, philosophers have stated that happiness is the ultimate source of human motivation. Therefore, many individuals think that the more positive emotions they experience, the happier they will be, and they strive for it. Many different situations such as socioeconomic level, educational status, gender, culture affect the level of happiness of individuals, but the desire to be happy is present in every segment. The endless pursuit of happiness can often lead to unrealistic expectations and some psychological problems in the face of life events. The increase in positive emotions can open up more space for the person to learn, think and develop together with happiness. However, positive emotions do not consist of happiness, but there are also different emotions that contribute to happiness and nourish the person. The positive emotions experienced by the person in daily life are important in terms of better performance and healthier relationships. In this respect, when we look at the literature on this subject, it has been seen that there is a gap in the studies conducted in Turkey. Emotions are important determinants of behavior. Any risky behavior that may arise can be harmful to both the individual and the society. Emotion regulation also affects behavior positively. For this purpose, the aim of this study is to deal with positive emotions, which have not been discussed before, in a theoretical dimension, to adapt these emotions to daily life, to increase the resources that the person has and to convey their reflections on the lifestyle.
- Published
- 2023
46. Solastalgia and Forest Fires
- Author
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Çiğdem ALACA
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
One of the important problems created by climate change is forest fires. Forest fires occur due to both natural and anthropogenic causes. Forest fires, which occur with the effects of climate change such as an increase in temperature, drought, heat waves, and climatic conditions, are increasing gradually. Acute and chronic effects caused by forest fires cause significant life changes. As a result of the fire, not only forests are damaged, but also flora, wildlife, water resources, soil, climate, areas used by people for recreational purposes, and settlements near and around forested areas. As a result, changes such as increases in temperature, pollution, epidemics, drought, food shortage, and forest fires, affect mental and physical health. While exposure to forest fires creates a direct traumatic effect; indirectly, it affects mental health for a number of social, political and economic reasons such as poverty, unemployment and housing. Forest fires also create an environmental change. This environmental change creates a sense of loss, the sense of belonging is lost, it cannot connect with the new environment, it becomes difficult to adapt and causes distress.Uncertainty about the future, helplessness, stress, anxiety, post-traumatic stress disorder and depression are common psychological problems due to climate change. It defines some new mental health concepts as the consequences of climate change affect mental health. "Solastalgia" is one pf these new concepts. Solastalgia is defined as a term that expresses the pain and distress caused by the loss of the thing/things that people find solace and environmental change. Solastalgia is a necessary concept for mental health professionals to understand the links between ecosystem health and human health, especially the cumulative effects of climatic and environmental change on mental, emotional and spiritual health.
- Published
- 2023
47. Imagery: A Review
- Author
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Güneş ÖZTÜRK
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
Modern neuroscience has shown that relaxing images cause the brain to release high levels of serotonin, dopamine, and oxytocin, which reduce anxiety, block cortisol, and increase neuroplasticity. Modern medicine positions human beings as passive, helpless, in need of external aid and in need of repair. However, man should be seen as a being with physical and spiritual power that can repair himself far beyond this passive role. The common point of all the studies examined in this study is that imagery, which is an internal skill, can be used as a low-cost and effective mental therapy tool. Some studies have described imagery as a more effective method than pharmacological interventions. It is seen that the application of imagery is widely used in many diseases such as psychotic disorders, cancer, asthma, migraine, hypertension, immune system diseases, mental disorders such as anxiety and depression. It is seen that the imagery technique, which is thought to work as a defense mechanism and drive satisfaction according to psychoanalytic perspective, is widely used in fields such as mindfulness-focused therapy, cognitive behavioral therapy, and dialectic therapy. This review, first of all, mentions the use of imagery and imagery in history, and then describes current research on imagery applications on different diseases. In addition, it was written to emphasize the lack of research on the mechanisms by which this personal and internal power, which is thought to affect the efficiency of the treatment, regardless of which physical or psychological help is sought, and to encourage new research.
- Published
- 2023
48. Psychosocial Aspects of Rehabilitation in Neurodegenerative Diseases and Fields of Approach
- Author
-
Pınar KAYA CİDDİ
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
Psychosocial health is a concept included in definition of health by World Health Organization and corresponds to state of emotional and social well-being. In the context of neurological disorder, psychosocial health refers to social reintegration and psychological adjustment. Studies reporting that neurological diseases are associated with negative psychosocial health outcomes such as a decrease in the quality of life, a decrease in ability to establish and maintain social relationships, and an increase in high levels of depression, stress and anxiety have increased in recent years. Therefore, it is important to consider programs and interventions that can improve the psychosocial health of people with neurodegenerative diseases. Currently, it is not clear which psychosocial approaches can produce definitively positive results. The aim of this study is to examine how being an individual with Multiple Sclerosis and Parkinson's, which are the most common neurodegenerative diseases in the clinic, affects psychosocial health in the rehabilitation process and the existing evidence-based psychosocial approaches. For this purpose, a descriptive review was prepared by scanning English and Turkish articles with keywords on psychotherapeutic, psychosocial and mindfulness-based interventions and stress management, published in the determined databases in the last 10 years. Studies have shown that psychosocial approaches such as interventions for acquisition of social integration and adaptive coping strategies, cognitive and social behavioral therapy methods, concentration and movement-based mind-body exercises are effective in rehabilitation of neurodegenerative diseases. These approaches were reported to have benefits in reducing anxiety, depression and fatigue, improving sleep quality and quality of life, relationships, employment, level of participation, motivation and self-efficacy in exercise and physical activity, improving physical functions, facilitating difficult and personal experiences and adaptation to new life in rehabilitation processes and more evidence-based studies are needed.
- Published
- 2023
49. Implicit Theory of Intelligence: Growth Mindset
- Author
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Mehmet Ali PADIR and Mehmet S. VANGÖLÜ
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
There has been a long-standing debate among scientists as to whether intelligence is something innate, tangible, fixed, and relatively unchanging, or whether intelligence is not fixed and unchanging, but rather something that can be developed, dynamic, shaped, and strengthened with effort. Carol Dweck and her colleagues, who have focused their studies in this field, have developed the implicit theory of intelligence, which deals with this topic. According to the implicit theory of intelligence, which is based on people's beliefs about the nature of their intelligence, these beliefs are the perspectives on whether the intellectual abilities of individuals are fixed or whether they can be developed or not. Implicit theory of intelligence; expresses people's beliefs related to their intelligence as a structure consisting of two parts: the growth mindset and the fixed mindset. The implicit theory of intelligence see intelligence as ranging from either being stable, fixed, unchangeable, and innate (fixed mindset) or being improvable, dynamic, malleable, and could be changed by effort or hard work (growth mindset). This theory has been renamed as growth mindset in the recent period. Shortly, growth mindset interventions. Express that human abilities are not fixed and these abilities can be developed. However, as a result of a detailed search in the national literature, it has been determined that there is no study growth mindset. Therefore, in this study, it is aimed to introduce growt mindset, whose effectiveness has been tested by many studies and evidence-based, especially to young researchers working in the academic field and field workers in Türkiye.
- Published
- 2023
50. Postpartum Paternal Depression: Its Impact on Family and Child Development
- Author
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Özge DEMİRCİ and Emine INAN
- Subjects
Psychiatry and Mental health ,Biological Psychiatry - Abstract
The postpartum period is when parents undergo great changes and gain new responsibilities. Factors such as the changes that come with having a baby, not meeting the expectations about parenthood, having a child with a difficult temperament or health problems, or relational problems can be quite challenging in this period. These problems can deeply affect the psychological well-being of the parents. Although studies on depressive symptoms of mothers during pregnancy and postpartum are at an important level, studies aiming to examine the psychological state of fathers for the same period are still limited. However, perceptions that postpartum depression develops due to hormonal changes during pregnancy have been reshaped by the findings that this situation may also develop due to psychosocial factors. Relatedly, the number of studies on postpartum depression experienced by fathers has increased over time. Results of those studies show that fathers' psychological state also influences their parenting and the development of children. Fathers may experience paternal depression due to a lack of social support, economic conditions, relationship dynamics, and changing living conditions in the postpartum period. This situation may cause fathers to avoid parenting duties, spend less time with their children, be unable to cooperate with the mother, and have anger problems or deterioration in the relationship with the mother. The effects of depression on individuals' parenting styles negatively affect child-parent attachment and may cause children to develop emotional and behavioral problems. Therefore, it is very important to examine fathers' psychological state for children's development and the healthy progress of family dynamics. This review aims to address the effect of paternal depression on parenting and child development.
- Published
- 2023
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