459 results on '"Przyborski, Stefan"'
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2. Current understanding of the interplay between extracellular matrix remodelling and gut permeability in health and disease
3. Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule
4. An essential role for the Zn2+ transporter ZIP7 in B cell development
5. Directed Mutagenesis for Arginine Substitution of a Phaseolus acutifolius Recombinant Lectin Disrupts Its Cytotoxic Activity.
6. Bioengineering the Human Intestinal Mucosa and the Importance of Stromal Support for Pharmacological Evaluation In Vitro.
7. How good is the evidence that cellular senescence causes skin ageing?
8. Germline TET2 loss of function causes childhood immunodeficiency and lymphoma
9. Cell Senescence-Independent Changes of Human Skin Fibroblasts with Age
10. Senescent Dermal Fibroblasts Decrease Stemness in Basal Keratinocytes in a Bioengineered Model of Human Full-Thickness Skin
11. Comparison of photodamage in non-pigmented and pigmented human skin equivalents exposed to repeated ultraviolet radiation to investigate the role of melanocytes in skin photoprotection.
12. Use of Porous Polystyrene Scaffolds to Bioengineer Human Epithelial Tissues In Vitro
13. Development of a novel in vitro strategy to understand the impact of shaving on skin health: combining tape strip exfoliation and human skin equivalent technology
14. Probing biological activity through structural modelling of ligand-receptor interactions of 2,4-disubstituted thiazole retinoids
15. Impact of the Physical Cellular Microenvironment on the Structure and Function of a Model Hepatocyte Cell Line for Drug Toxicity Applications
16. A robust and reproducible human pluripotent stem cell derived model of neurite outgrowth in a three-dimensional culture system and its application to study neurite inhibition
17. An in vitro model to study immune activation, epithelial disruption and stromal remodelling in inflammatory bowel disease and fistulising Crohn's disease.
18. Neurogenesis in Response to Synthetic Retinoids at Different Temporal Scales
19. Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms
20. Engineering a Multilayered Skin Equivalent: The Importance of Endogenous Extracellular Matrix Maturation to Provide Robustness and Reproducibility
21. Supplementary Figure 1 Legend: Early cutaneous invasion of WM35 melanoma cells in full-thickness human skin equivalents results in disruption of basement membrane component type IV collagen from A Novel Fully Humanized 3D Skin Equivalent to Model Early Melanoma Invasion
22. Data from A Novel Fully Humanized 3D Skin Equivalent to Model Early Melanoma Invasion
23. Supplementary Figure 1: Early cutaneous invasion of WM35 melanoma cells in full-thickness human skin equivalents results in disruption of basement membrane component type IV collagen from A Novel Fully Humanized 3D Skin Equivalent to Model Early Melanoma Invasion
24. Quantitative morphometric analysis of intrinsic and extrinsic skin ageing in individuals with Fitzpatrick skin types II–III
25. Neuronal-glial populations form functional networks in a biocompatible 3D scaffold
26. The Development of Small Molecules and Growth Supplements to Control the Differentiation of Stem Cells and the Formation of Neural Tissues
27. Regulation of epidermal proliferation and hair follicle cycling by synthetic photostable retinoid EC23
28. Development of a mammalian neurosensory full‐thickness skin equivalent and its application to screen sensitizing stimuli
29. Alvetex®, a highly porous polystyrene scaffold for routine three-dimensional cell culture
30. An introduction to the third dimension for routine cell culture
31. Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa
32. Investigation into the effect of skin tone modulators and exogenous stress on skin pigmentation utilizing a novel bioengineered skin equivalent
33. Early onset of senescence and imbalanced epidermal homeostasis across the decades in photoexposed human skin: Fingerprints of inflammaging
34. iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors
35. A Role for NANOG in G1 to S Transition in Human Embryonic Stem Cells through Direct Binding of CDK6 and CDC25A
36. Role of mesenchymal stem cells in neurogenesis and nervous system repair
37. Neuropharmacological properties of neurons derived from human stem cells
38. Neurite formation by neurons derived from adult rat hippocampal progenitor cells is susceptible to myelin inhibition
39. Recreating Tissue Structures Representative of Teratomas In Vitro Using a Combination of 3D Cell Culture Technology and Human Embryonic Stem Cells
40. Inflammaging in human photoexposed skin: Early onset of senescence and imbalanced epidermal homeostasis across the decades
41. Histone Demethylation and Toll-like Receptor 8–Dependent Cross-Talk in Monocytes Promotes Transdifferentiation of Fibroblasts in Systemic Sclerosis Via Fra-2
42. Investigation into the effect of skin tone modulators and exogenous stress on skin pigmentation utilizing a novel bioengineered skin equivalent.
43. Retinoid supplementation of differentiating human neural progenitors and embryonic stem cells leads to enhanced neurogenesis in vitro
44. Validation of reference gene stability for APAP hepatotoxicity studies in different in vitro systems and identification of novel potential toxicity biomarkers
45. Tissue engineering strategies to bioengineer the ageing skin phenotype in vitro
46. Basal Mitophagy is Suppressed in Cellular Senescence and Mediates Senescence Phenotypes
47. Advances in 3D cell culture technologies enabling tissue-like structures to be created in vitro
48. Mesenchymal stem cells expressing neural antigens instruct a neurogenic cell fate on neural stem cells
49. Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
50. The Cell-Permeable Derivative of the Immunoregulatory Metabolite Itaconate, 4-Octyl Itaconate, Is Anti-Fibrotic in Systemic Sclerosis
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