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3. Ketamine in Severe Leptomeningeal Pain

Author

Tam, Yong Seng, primary, Chen, Elizabeth, additional, Poh, ZhiSheng Edmund, additional, Chia, Gerksin, additional, Provido, Mahrley, additional, Hum, Allyn, additional, and Lee, Hsien Xiong, additional

Published
2022
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4. Ketamine in Severe Leptomeningeal Pain.

Author

Tam, Yong Seng, Chen, Elizabeth, Poh, ZhiSheng Edmund, Chia, Gerksin, Provido, Mahrley, Hum, Allyn, and Lee, Hsien Xiong

Subjects
CANCER pain, MENINGEAL cancer, TERMINALLY ill, NEURALGIA, GLIOMAS, MENINGES, KETAMINE, MENINGITIS, OPIOID analgesics, INTRACRANIAL hypertension, DISEASE complications
Abstract

Carcinomatosis meningitis is a rare but deadly complication of medulloblastoma. Surgical and systemic treatment options are often limited in advanced stages of the cancer. Meningeal irritation from raised intracranial pressure causes leptomeningeal pain that may respond poorly to opioids and common adjuvant analgesics. We present the case of a terminally ill patient with severe leptomeningeal pain that responded to a trial of ketamine as an adjunct to opioids. [ABSTRACT FROM AUTHOR]

Published
2023
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