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5. SARS-CoV-2 vaccination and multiple sclerosis: a large multicentric study on relapse risk after the third booster dose

Author

Di Filippo, Massimiliano, Ferraro, Diana, Ragonese, Paolo, Prosperini, Luca, Maniscalco, Giorgia Teresa, Gallo, Antonio, Cavalla, Paola, Lorefice, Lorena, Nociti, Viviana, Di Sabatino, Elena, Clerico, Marinella, Guaschino, Clara, Radaelli, Marta, Fantozzi, Roberta, Buttari, Fabio, Laroni, Alice, Gajofatto, Alberto, Calabrese, Massimiliano, Malucchi, Simona, Paolicelli, Damiano, De Luca, Giovanna, Tomassini, Valentina, Lanzillo, Roberta, Moccia, Marcello, Solaro, Claudio, Cocco, Eleonora, Gasperini, Claudio, and Tortorella, Carla

Published
2024
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14. Parent Training and Communication Empowerment of Children with Cochlear Implant

Author

Nicastri, Maria, Giallini, Ilaria, Ruoppolo, Giovanni, Prosperini, Luca, de Vincentiis, Marco, Lauriello, Maria, Rea, Monica, Traisci, Gabriella, and Mancini, Patrizia

Abstract

Deaf children with cochlear implants (CIs) need a supportive family environment to facilitate language development. The present study was designed to assess the effects of parent training (PT) on enhancing children's communication development. The PT was based on the "It Takes Two to Talk" model, with specific adaptations for families of deaf children. Before and after the PT, 14 participating families and matched no-treatment controls were assessed using the Parent Stress Index and Cole's interaction checklist. The children's language was assessed with the MacArthur-Bates Communicative Development Inventory and, after 3 years, with the Boston Naming, the Peabody, and the Test for Reception of Grammar--Version 2 (TROG-2). The families' quality of interaction and the children's language increased significantly more in the trained group than in controls and differences were still present after 3 years. The parents seemed to benefit from PT that focused on strategies to empower and promote communication skills in children with CIs.

Published
2021
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15. Post-natalizumab disease reactivation in multiple sclerosis: systematic review and meta-analysis.

Author

Prosperini, Luca, Kinkel, Revere, Miravalle, Augusto, Iaffaldano, Pietro, and Fantaccini, Simone

Subjects
discontinuation, meta-analysis, natalizumab, relapsing–remitting multiple sclerosis
Abstract

BACKGROUND: Natalizumab (NTZ) is sometimes discontinued in patients with multiple sclerosis, mainly due to concerns about the risk of progressive multifocal leukoencephalopathy. However, NTZ interruption may result in recrudescence of disease activity. OBJECTIVE: The objective of this study was to summarize the available evidence about NTZ discontinuation and to identify which patients will experience post-NTZ disease reactivation through meta-analysis of existing literature data. METHODS: PubMed was searched for articles reporting the effects of NTZ withdrawal in adult patients (⩾18 years) with relapsing-remitting multiple sclerosis (RRMS). Definition of disease activity following NTZ discontinuation, proportion of patients who experienced post-NTZ disease reactivation, and timing to NTZ discontinuation to disease reactivation were systematically reviewed. A generic inverse variance with random effect was used to calculate the weighted effect of patients clinical characteristics on the risk of post-NTZ disease reactivation, defined as the occurrence of at least one relapse. RESULTS: The original search identified 205 publications. Thirty-five articles were included in the systematic review. We found a high level of heterogeneity across studies in terms of sample size (10 to 1866 patients), baseline patient characteristics, follow up (1-24 months), outcome measures (clinical and/or radiological), and definition of post-NTZ disease reactivation or rebound. Clinical relapses were observed in 9-80% of patients and peaked at 4-7 months, whereas radiological disease activity was observed in 7-87% of patients starting at 6 weeks following NTZ discontinuation. The meta-analysis of six articles, yielding a total of 1183 patients, revealed that younger age, higher number of relapses and gadolinium-enhanced lesions before treatment start, and fewer NTZ infusions were associated with increased risk for post-NTZ disease reactivation (p ⩽ 0.05). CONCLUSIONS: Results from the present review and meta-analysis can help to profile patients who are at greater risk of post-NTZ disease reactivation. However, potential reporting bias and variability in selected studies should be taken into account when interpreting our data.

Published
2019

18. Disability patterns in multiple sclerosis: A meta-analysis on RAW and PIRA in the real-world context.

Author

Prosperini, Luca, Ruggieri, Serena, Haggiag, Shalom, Tortorella, Carla, and Gasperini, Claudio

Subjects
*SCIENCE databases, *MULTIPLE sclerosis, *SCIENTIFIC method, *CONFIDENCE intervals, *DISABILITIES
Abstract

Objective: To summarize the current evidence on relapse-associated worsening (RAW) and progression independent of relapse activity (PIRA) through a quantitative synthesis of real-world studies. Methods: Scientific databases were searched to identify suitable articles. Random-effects meta-analyses, subgroup analyses and meta-regression models were ran to provide pooled estimates of RAW and PIRA events and to identify their potential moderators (PROSPERO registration: CRD42024503895). Results: Eighteen articles met the eligibility criteria, with a pooled sample size of 52,667 patients (93% relapsing–remitting, 6% clinically isolated syndrome and 1% progressive) followed for 2.4 to 12.1 years, yielding to 415,825 patient-years. Pooled event rates for RAW and PIRA were 1.6 (95 confidence interval (CI) = 1.1–2.1) and 3.1 (95% CI = 2.3–3.9) per 100 patient-years, respectively. Less RAW events were found in cohorts including patients with progressive course (β = −0.069, p = 0.006) and under high-efficacy disease-modifying treatments (DMTs) (β = −0.031, p = 0.007), while PIRA events were directly related to older age (β = 0.397, p = 0.027). In addition, we found significant differences in PIRA event rates according to the criteria adopted to define confirmed disability accrual (p < 0.05). Discussion: PIRA accounts for most events causing disability accumulation in the real-world setting, even at the earlier disease stages, whereas RAW represents a less frequent phenomenon, likely due to effective treatments. The detection and statistical analysis of PIRA outcomes pose challenges, raising the risk of erroneous inference. When interpreting our findings, caution is needed given the wide heterogeneity of included studies. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Brain reserve and timing of clinical onset in multiple sclerosis.

Author

Petracca, Maria, Ruggieri, Serena, Nistri, Riccardo, Tomasso, Ilaria, Barbuti, Elena, Pozzilli, Valeria, Haggiag, Shalom, Tortorella, Carla, Gasperini, Claudio, Pozzilli, Carlo, and Prosperini, Luca

Subjects
PROPORTIONAL hazards models, CENTRAL nervous system, NEURAL development, SYMPTOMS, MULTIPLE sclerosis
Abstract

Background: A latent period of variable length elapses between multiple sclerosis (MS) biological onset and the occurrence of the first clinical episode reflecting a central nervous system (CNS) demyelinating event. Factors affecting the duration of such interval are unknown. Objective: To explore whether brain reserve, which moderates the impact of structural damage along MS course, could also affect the timing of MS clinical onset. Methods: We conducted a time-to-event analysis in 326 relapsing-onset multiple sclerosis patients to ascertain the effect of brain reserve, that is, larger maximal lifetime brain growth (MLBG) estimated as intracranial volume, on the risk of an earlier disease onset. For this purpose, we carried out a Cox proportional hazards regression model stratified by sex and adjusted by site and pre-morbid MS risk factors. All patients reached the event (i.e. the disease onset) with no censored case; the age (years) at disease onset was set as the main time variable. Results: We identified a protective effect of brain reserve on the time to disease onset (HR = 0.11, 95% CI = 0.02–0.83, p = 0.032), unchanged when accounting for MS risk factors. Conclusion: Brain reserve might counteract the pathological mechanisms ongoing after biological initiation, thus delaying the disease overt clinical manifestation. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Treatment response scoring systems to assess long-term prognosis in self-injectable DMTs relapsing–remitting multiple sclerosis patients

Author

Río, Jordi, Rovira, Àlex, Gasperini, Claudio, Tintoré, Mar, Prosperini, Luca, Otero-Romero, Susana, Comabella, Manuel, Vidal-Jordana, Ángela, Galán, Ingrid, Midaglia, Luciana, Rodriguez-Acevedo, Breogán, Zabalza, Ana, Castilló, Joaquim, Arrambide, Georgina, Nos, Carlos, Cobo, Álvaro, Tur, Carmen, Auger, Cristina, Sastre-Garriga, Jaume, and Montalban, Xavier

Published
2022
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25. Effect of an interactive Pilates-based telerehabilitation intervention in people with multiple sclerosis: Protocol for a Randomized Controlled Trial. (Preprint)

Author

Tacchino, Andrea, primary, Ponzio, Michela, additional, Confalonieri, Paolo, additional, Leocani, Letizia, additional, Inglese, Matilde, additional, Centonze, Diego, additional, Cocco, Eleonora, additional, Gallo, Paolo, additional, Paolicelli, Damiano, additional, Rovaris, Marco, additional, Sabattini, Loredana, additional, Tedeschi, Gioacchino, additional, Prosperini, Luca, additional, Patti, Francesco, additional, Sessa, Edoardo, additional, Pedrazzoli, Elisabetta, additional, Battaglia, Mario Alberto, additional, and Brichetto, Giampaolo, additional

Published
2024
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28. Real world experience with teriflunomide in multiple sclerosis: the TER-Italy study

Author

Bucello, Sebastiano, Annovazzi, Pietro, Ragonese, Paolo, Altieri, Marta, Barcella, Valeria, Bergamaschi, Roberto, Bianchi, Alessia, Borriello, Giovanna, Buscarinu, Maria Chiara, Callari, Graziella, Capobianco, Marco, Capone, Fioravante, Cavalla, Paola, Cavarretta, Rosella, Cortese, Antonio, De Luca, Giovanna, Di Filippo, Massimiliano, Dattola, Vincenzo, Fantozzi, Roberta, Ferraro, Elisabetta, Filippi, Maria Maddalena, Gasperini, Claudio, Grimaldi, Luigi Maria Edoardo, Landi, Doriana, Re, Marianna Lo, Mallucci, Giulia, Manganotti, Paolo, Marfia, Girolama Alessandra, Mirabella, Massimiliano, Perini, Paola, Pisa, Marco, Realmuto, Sabrina, Russo, Margherita, Tomassini, Valentina, Torri-Clerici, Valentina Liliana Adriana, Zaffaroni, Mauro, Zuliani, Cristina, Zywicki, Sofia, Filippi, Massimo, and Prosperini, Luca

Published
2021
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30. Predictors of lymphocyte count recovery after dimethyl fumarate-induced lymphopenia in people with multiple sclerosis

Author

Lucchini, Matteo, Prosperini, Luca, Buscarinu, Maria Chiara, Centonze, Diego, Conte, Antonella, Cortese, Antonio, Elia, Giorgia, Fantozzi, Roberta, Ferraro, Elisabetta, Gasperini, Claudio, Ianniello, Antonio, Landi, Doriana, Marfia, Girolama Alessandra, Nociti, Viviana, Pozzilli, Carlo, Salvetti, Marco, Tortorella, Carla, and Mirabella, Massimiliano

Published
2021
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32. Anti-RBD Antibody Levels and IFN-γ-Specific T Cell Response Are Associated with a More Rapid Swab Reversion in Patients with Multiple Sclerosis after the Booster Dose of COVID-19 Vaccination.

Author

Aiello, Alessandra, Ruggieri, Serena, Navarra, Assunta, Tortorella, Carla, Vanini, Valentina, Haggiag, Shalom, Prosperini, Luca, Cuzzi, Gilda, Salmi, Andrea, Quartuccio, Maria Esmeralda, Altera, Anna Maria Gerarda, Meschi, Silvia, Matusali, Giulia, Vita, Serena, Galgani, Simonetta, Maggi, Fabrizio, Nicastri, Emanuele, Gasperini, Claudio, and Goletti, Delia

Subjects
BOOSTER vaccines, BREAKTHROUGH infections, COVID-19 vaccines, ANTIBODY formation, T cells
Abstract

This study investigated the incidence and severity of SARS-CoV-2 breakthrough infections (BIs) and the time to swab reversion in patients with multiple sclerosis (PwMS) after the booster dose of COVID-19 mRNA vaccines. We enrolled 64 PwMS who had completed the three-dose mRNA vaccine schedule and had never experienced COVID-19 before. Among the 64 PwMS, 43.8% had BIs with a median time since the third vaccine dose of 155 days. BIs occurred more frequently in ocrelizumab-treated patients (64.7%). Patients with a relapsing-remitting MS course showed a reduced incidence of BIs compared with those with a primary-progressive disease (p = 0.002). Having anti-receptor-binding domain (RBD) antibodies represented a protective factor reducing the incidence of BIs by 60% (p = 0.042). The majority of BIs were mild, and the only severe COVID-19 cases were reported in patients with a high Expanded Disability Status Scale score (EDSS > 6). The median time for a negative swab was 11 days. Notably, fingolimod-treated patients take longer for a swab-negativization (p = 0.002). Conversely, having anti-RBD antibodies ≥ 809 BAU/mL and an IFN-γ-specific T cell response ≥ 16 pg/mL were associated with a shorter time to swab-negativization (p = 0.051 and p = 0.018, respectively). In conclusion, the immunological protection from SARS-CoV-2 infection may differ among PwMS according to DMTs. [ABSTRACT FROM AUTHOR]

Published
2024
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34. Creutzfeldt–Jakob Disease Associated with E200K Mutation and SARS-CoV-2 Infection: Pure Coincidence or Neurodegenerative Acceleration?

Author

Colaizzo, Elisa, Prosperini, Luca, Petrucci, Antonio, and Perna, Alessia

Subjects
CREUTZFELDT-Jakob disease, GENETIC mutation, NEURODEGENERATION, COVID-19, FAMILY history (Medicine)
Abstract

Several recent studies reported on some patients developing Creutzfeldt–Jakob disease (CJD) following coronavirus disease 2019, but, to the best of our knowledge, this case is the first reported in Italy on an onset of a CJD genetic form (gCJD) immediately after COVID-19 infection. We present a 51-year-old woman with a positive family history for CJD, who, two months after a mild SARS-CoV-2 infection, presented a rapidly progressing dementia diagnosed as CJD through clinical features, imaging, electroencephalography, and cerebrospinal fluid analysis. Genetic testing revealed the E200K mutation (p.Glu200Lys) c.598G>A, with homozygosity for methionine (MET) at codon 129, thus confirming the diagnosis of Creutzfeldt–Jakob disease. She passed away two months later. Interestingly, our case confirms that homozygous E200K gCJD patients are characterized by a relatively younger age of onset; moreover, it also sheds light on the neurodegeneration underlying both prion diseases and COVID-19 infection. In our opinion, the rising global prevalence of neurodegenerative complications following COVID-19 disease adds urgency to the study of this potential relationship, mostly in elderly patients who may experience worse long-lasting outcomes systemically and within the nervous system. [ABSTRACT FROM AUTHOR]

Published
2024
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36. Humoral- and T-Cell–Specific Immune Responses to SARS-CoV-2 mRNA Vaccination in Patients With MS Using Different Disease-Modifying Therapies

Author

Tortorella, Carla, Aiello, Alessandra, Gasperini, Claudio, Agrati, Chiara, Castilletti, Concetta, Ruggieri, Serena, Meschi, Silvia, Matusali, Giulia, Colavita, Francesca, Farroni, Chiara, Cuzzi, Gilda, Cimini, Eleonora, Tartaglia, Eleonora, Vanini, Valentina, Prosperini, Luca, Haggiag, Shalom, Galgani, Simona, Quartuccio, Maria Esmeralda, Salmi, Andrea, Repele, Federica, Gerarda Altera, Anna Maria, Cristofanelli, Flavia, DʼAbramo, Alessandra, Bevilacqua, Nazario, Corpolongo, Angela, Puro, Vincenzo, Vaia, Francesco, Capobianchi, Maria Rosaria, Ippolito, Giuseppe, Nicastri, Emanuele, and Goletti, Delia

Published
2021
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39. Italian translation and psychometric validation of the Manual Ability Measure-36 (MAM-36) and its correlation with an objective measure of upper limb function in patients with multiple sclerosis

Author

Solaro, Claudio, Di Giovanni, Rachele, Grange, Erica, Brichetto, Giampaolo, Mueller, Margit, Tacchino, Andrea, Bertoni, Rita, Patti, Francesco, Pappalardo, Angelo, Prosperini, Luca, Castelli, Letizia, Rosato, Rosalba, Cattaneo, Davide, and Marengo, Davide

Published
2020
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42. Exit strategies for “needle fatigue” in multiple sclerosis: a propensity score-matched comparison study

Author

Prosperini, Luca, Cortese, Antonio, Lucchini, Matteo, Boffa, Laura, Borriello, Giovanna, Buscarinu, Maria Chiara, Capone, Fioravante, Centonze, Diego, De Fino, Chiara, De Pascalis, Daniela, Fantozzi, Roberta, Ferraro, Elisabetta, Filippi, Maria, Galgani, Simonetta, Gasperini, Claudio, Haggiag, Shalom, Landi, Doriana, Marfia, Girolama, Mataluni, Giorgia, Millefiorini, Enrico, Mirabella, Massimiliano, Monteleone, Fabrizia, Nociti, Viviana, Pontecorvo, Simona, Romano, Silvia, Ruggieri, Serena, Salvetti, Marco, Tortorella, Carla, Zannino, Silvana, and Di Battista, Giancarlo

Published
2020
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43. COVID-19 Severity in Multiple Sclerosis: Putting Data Into Context

Author

Sormani, Maria Pia, Schiavetti, Irene, Carmisciano, Luca, Cordioli, Cinzia, Filippi, Massimo, Radaelli, Marta, Immovilli, Paolo, Capobianco, Marco, De Rossi, Nicola, Brichetto, Giampaolo, Cocco, Eleonora, Scandellari, Cinzia, Cavalla, Paola, Pesci, Ilaria, Zito, Antonio, Confalonieri, Paolo, Marfia, Girolama Alessandra, Perini, Paola, Inglese, Matilde, Trojano, Maria, Brescia Morra, Vincenzo, Tedeschi, Gioacchino, Comi, Giancarlo, Battaglia, Mario Alberto, Patti, Francesco, Salvetti, Marco, Abbadessa, Gianmarco, Aguglia, Umberto, Allegorico, Lia, Allegri Rossi, Beatrice Maria, Amato, Maria Pia, Annovazzi, Pietro, Antozzi, Carlo, Appendino, Lucia, Arena, Sebastiano, Baione, Viola, Balgera, Roberto, Barcella, Valeria, Baroncini, Damiano, Barrilà, Caterina, Bellacosa, Alessandra, Bellucci, Gianmarco, Bergamaschi, Roberto, Bergamaschi, Valeria, Bezzini, Daiana, Biolzi, Beatrice, Bisecco, Alvino, Bonavita, Simona, Borriello, Giovanna, Bosa, Chiara, Bosco, Antonio, Bovis, Francesca, Bozzali, Marco, Brambilla, Laura, Buccafusca, Maria, Bucciantini, Elisabetta, Bucello, Sebastiano, Buscarinu, Maria Chiara, Cabboi, Maria Paola, Calabrese, Massimiliano, Calabria, Francesca, Caleri, Francesca, Camilli, Federico, Caniatti, Luisa Maria, Cantello, Roberto, Capra, Ruggero, Capuano, Rocco, Carta, Patrizia, Celani, Maria Grazia, Cellerino, Maria, Cerqua, Raffaella, Chisari, Clara, Clerici, Raffaella, Clerico, Marinella, Cola, Gaia, Conte, Antonella, Conti, Marta Zaffira, Cordano, Christian, Cordera, Susanna, Corea, Francesco, Correale, Claudio, Cottone, Salvatore, Crescenzo, Francesco, Curti, Erica, dʼAmbrosio, Alessandro, DʼAmico, Emanuele, Danni, Maura Chiara, dʼArma, Alessia, Dattola, Vincenzo, de Biase, Stefano, Luca, Giovanna De, Mercanti, Stefania Federica De, De Mitri, Paolo, De Stefano, Nicola, Cava, Marco Della, Napoli, Mario di, Sapio, Alessia Di, Docimo, Renato, Dutto, Anna, Evangelista, Luana, Fanara, Salvatore, Diana, Ferraro, Ferrò, Maria Teresa, Fioretti, Cristina, Fratta, Mario, Frau, Jessica, Fronza, Marzia, Furlan, Roberto, Gajofatto, Alberto, Gallo, Antonio, Gallo, Paolo, Gasperini, Claudio, Ghazaryan, Anna, Giometto, Bruno, Gobbin, Francesca, Govone, Flora, Granella, Franco, Grange, Erica, Grasso, Maria Grazia, Guareschi, Angelica, Guaschino, Clara, Guerrieri, Simone, Guidetti, Donata, Iaffaldano, Pietro, Ianniello, Antonio, Iasevoli, Luigi, Imperiale, Daniele, Infante, Maria Teresa, Iodice, Rosa, Iovino, Aniello, Konrad, Giovanna, Landi, Doriana, Lanzillo, Roberta, Lapucci, Caterina, Lavorgna, Luigi, LʼEpiscopo, Maria Rita, Leva, Serena, Liberatore, Giuseppe, Lo Re, Marianna, Longoni, Marco, Lopiano, Leonardo, Lorefice, Lorena, Lucchini, Matteo, Lus, Giacomo, Maimone, Davide, Malentacchi, Maria, Mallucci, Giulia, Malucchi, Simona, Mancinelli, Chiara Rosa, Mancinelli, Luca, Manganotti, Paolo, Maniscalco, Giorgia Teresa, Mantero, Vittorio, Marangoni, Sabrina, Marastoni, Damiano, Marinelli, Fabiana, Marti, Alessandro, Boneschi, Filippo Martinelli, Masserano Zoli, Federco, Matta, Francesca, Mendozzi, Laura, Meucci, Giuseppe, Miante, Silvia, Miele, Giuseppina, Milano, Eva, Mirabella, Massimiliano, Missione, Rosanna, Moccia, Marcello, Moiola, Lucia, Montepietra, Sara, MontiBragadin, Margherita, Montini, Federico, Motta, Roberta, Nardone, Raffaele, Nicoletti, Carolina Gabri, Nobile-Orazio, Eduardo, Nozzolillo, Agostino, Onofrj, Marco, Orlandi, Riccardo, Palmieri, Anna, Paolicelli, Damiano, Pasquali, Livia, Pastò, Luisa, Pedrazzoli, Elisabetta, Petracca, Maria, Petrone, Alfredo, Piantadosi, Carlo, Pietroboni, Anna M, Pinardi, Federica, Ponzano, Marta, Portaccio, Emilio, Pozzato, Mattia, Pozzilli, Carlo, Prosperini, Luca, Protti, Alessandra, Ragonese, Paolo, Rasia, Sarah, Realmuto, Sabrina, Repice, Anna, Rigoni, Eleonora, Rilla, Maria Teresa, Rinaldi, Francesca, Romano, Calogero Marcello, Ronzoni, Marco, Rovaris, Marco, Ruscica, Francesca, Sabattini, Loredana, Salemi, Giuseppe, Saraceno, Lorenzo, Sartori, Alessia, Sartori, Arianna, Sbragia, Elvira, Scarano, Giuditta Ilaria, Scarano, Valentina, Schillaci, Valentina, Sessa, Maria, Sgarito, Caterina, Sibilia, Grazia, Siciliano, Gabriele, Signori, Alessio, Signoriello, Elisabetta, Sinisi, Leonardo, Sireci, Francesca, Sola, Patrizia, Solaro, Claudio, Sotgiu, Stefano, Sparaco, Maddalena, Stromillo, Maria Laura, Strumia, Silvia, Susani, Emanuela Laura, Tabiadon, Giulietta, Teatini, Francesco, Tomassini, Valentina, Tonietti, Simone, Torri, Clerici Valentina, Tortorella, Carla, Toscano, Simona, Totaro, Rocco, Trotta, Maria, Turano, Gabriella, Ulivelli, Monica, Valentino, Manzo, Vaula, Giovanna, Vecchio, Domizia, Vercellino, Marco, Verrengia, Elena Pinuccia, Vianello, Marika, Virgilio, Eleonora, Vitetta, Francesca, Vollaro, Stefano, Zaffaroni, Mauro, Zampolini, Mauro, Zarbo, Ignazio Roberto, and Zuliani, Luigi

Published
2022
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46. An Internet- and Kinect-Based Multiple Sclerosis Fitness Intervention Training With Pilates Exercises: Development and Usability Study

Author

Tacchino, Andrea, primary, Ponzio, Michela, additional, Confalonieri, Paolo, additional, Leocani, Letizia, additional, Inglese, Matilde, additional, Centonze, Diego, additional, Cocco, Eleonora, additional, Gallo, Paolo, additional, Paolicelli, Damiano, additional, Rovaris, Marco, additional, Sabattini, Loredana, additional, Tedeschi, Gioacchino, additional, Prosperini, Luca, additional, Patti, Francesco, additional, Bramanti, Placido, additional, Pedrazzoli, Elisabetta, additional, Battaglia, Mario Alberto, additional, and Brichetto, Giampaolo, additional

Published
2023
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47. Assessing treatment response to oral drugs for multiple sclerosis in real-world setting: a MAGNIMS Study

Author

Ruggieri, Serena, primary, Prosperini, Luca, additional, Al-Araji, Sarmad, additional, Annovazzi, Pietro Osvaldo, additional, Bisecco, Alvino, additional, Ciccarelli, Olga, additional, De Stefano, Nicola, additional, Filippi, Massimo, additional, Fleischer, Vinzenz, additional, Evangelou, Nikos, additional, Enzinger, Christian, additional, Gallo, Antonio, additional, Garjani, Afagh, additional, Groppa, Sergiu, additional, Haggiag, Shalom, additional, Khalil, Michael, additional, Lucchini, Matteo, additional, Mirabella, Massimiliano, additional, Montalban, Xavier, additional, Pozzilli, Carlo, additional, Preziosa, Paolo, additional, Río, Jordi, additional, Rocca, Maria A, additional, Rovira, Alex, additional, Stromillo, Maria L, additional, Zaffaroni, Mauro, additional, Tortorella, Carla, additional, and Gasperini, Claudio, additional

Published
2023
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49. No evidence of disease activity (NEDA-3) and disability improvement after alemtuzumab treatment for multiple sclerosis: a 36-month real-world study

Author

Prosperini, Luca, Annovazzi, Pietro, Boffa, Laura, Buscarinu, Maria Chiara, Gallo, Antonio, Matta, Manuela, Moiola, Lucia, Musu, Luigina, Perini, Paola, Avolio, Carlo, Barcella, Valeria, Bianco, Assunta, Farina, Deborah, Ferraro, Elisabetta, Pontecorvo, Simona, Granella, Franco, Grimaldi, Luigi M. E., Laroni, Alice, Lus, Giacomo, Patti, Francesco, Pucci, Eugenio, Pasca, Matteo, and Sarchielli, Paola

Published
2018
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50. Correction to: Treatment response scoring systems to assess long-term prognosis in self-injectable DMTs relapsing–remitting multiple sclerosis patients

Author

Río, Jordi, Rovira, Àlex, Gasperini, Claudio, Tintoré, Mar, Prosperini, Luca, Otero-Romero, Susana, Comabella, Manuel, Vidal-Jordana, Ángela, Galán, Ingrid, Midaglia, Luciana, Rodriguez-Acevedo, Breogán, Zabalza, Ana, Castilló, Joaquim, Arrambide, Georgina, Nos, Carlos, Cobo-Calvo, Álvaro, Tur, Carmen, Auger, Cristina, Sastre-Garriga, Jaume, and Montalban, Xavier

Published
2022
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