Search

Your search keyword '"Procyshyn, Ric M"' showing total 559 results
Start Over Author "Procyshyn, Ric M"
559 results on '"Procyshyn, Ric M"'

2. Exploring low clozapine C/D ratios, inverted clozapine-norclozapine ratios and undetectable concentrations as measures of non-adherence in clozapine patients: A literature review and a case series of 17 patients from 3 studies

Author

Ruan, Can-Jun, Olmos, Ismael, Ricciardi, Carina, Schoretsanitis, Georgios, Vincent, Philippe D., Anıl Yağcıoğlu, A. Elif, Eap, Chin B., Baptista, Trino, Clark, Scott R., Fernandez-Egea, Emilio, Kim, Se Hyun, Lane, Hsien-Yuan, Leung, Jonathan, Maroñas Amigo, Olalla, Motuca, Mariano, Every-Palmer, Susanna, Procyshyn, Ric M., Rohde, Christopher, Suhas, Satish, Schulte, Peter F.J., Spina, Edoardo, Takeuchi, Hiroyoshi, Verdoux, Hélène, Correll, Christoph U., Molden, Espen, De Las Cuevas, Carlos, and de Leon, Jose

Published
2024
Full Text
View/download PDF

3. Clozapine ultrarapid metabolism during weak induction probably exists but requires careful diagnosis. A literature review, five new cases and a proposed definition

Author

Schoretsanitis, Georgios, Anıl Yağcıoğlu, A. Elif, Ruan, Can-Jun, Eap, Chin B., Molden, Espen, Baptista, Trino, Clark, Scott R., Fernandez-Egea, Emilio, Kim, Se Hyun, Lane, Hsien-Yuan, Leung, Jonathan, Maroñas Amigo, Olalla, Motuca, Mariano, Olmos, Ismael, Every-Palmer, Susanna, Procyshyn, Ric M., Rohde, Christopher, Satish, Suhas, Schulte, Peter F.J., Spina, Edoardo, Takeuchi, Hiroyoshi, Verdoux, Hélène, Correll, Christoph U., and de Leon, Jose

Published
2024
Full Text
View/download PDF

5. Guía internacional para una dosificación más segura de la clozapina en adultos mediante el uso de 6 titulaciones personalizadas de dosis basados en la etnicidad, la proteína C reactiva y los niveles de clozapina

Author

de Leon, Jose, Schoretsanitis, Georgios, Smith, Robert L., Molden, Espen, Solismaa, Anssi, Seppälä, Niko, Kopeček, Miloslav, Švancer, Patrik, Olmos, Ismael, Ricciardi, Carina, Iglesias-Garcia, Celso, Iglesias-Alonso, Ana, Spina, Edoardo, Ruan, Can-Jun, Wang, Chuan-Yue, Wang, Gang, Tang, Yi-Lang, Lin, Shih-Ku, Lane, Hsien-Yuan, Kim, Yong Sik, Kim, Se Hyun, Rajkumar, Anto P., González-Esquivel, Dinora F., Jung-Cook, Helgi, Baptista, Trino, Rohde, Christopher, Nielsen, Jimmi, Verdoux, Hélène, Quiles, Clelia, Sanz, Emilio J., De las Cuevas, Carlos, Cohen, Dan, Schulte, Peter F.J., Ertuğrul, Aygün, Anıl Yağcıoğlu, A. Elif, Chopra, Nitin, McCollum, Betsy, Shelton, Charles, Cotes, Robert O., Kaithi, Arun R., Kane, John M., Farooq, Saeed, Ng, Chee H., Bilbily, John, Hiemke, Christoph, López-Jaramillo, Carlos, McGrane, Ian, Lana, Fernando, Eap, Chin B., Arrojo-Romero, Manuel, Rădulescu, Flavian Ştefan, Seifritz, Erich, Every-Palmer, Susanna, Bousman, Chad A., Bebawi, Emmanuel, Bhattacharya, Rahul, Kelly, Deanna L., Otsuka, Yuji, Lazary, Judit, Torres, Rafael, Yecora, Agustin, Motuca, Mariano, Chan, Sherry Kit Wa, Zolezzi, Monica, Ouanes, Sami, De Berardis, Domenico, Grover, Sandeep, Procyshyn, Ric M., Adebayo, Richard A., Kirilochev, Oleg O., Soloviev, Andrey, Fountoulakis, Konstantinos N., Wilkowska, Alina, Cubała, Wiesław Jerzy, Ayub, Muhammad, Silva, Alzira, Bonelli, Raphael M., Villagrán-Moreno, José María, Crespo-Facorro, Benedicto, Temmingh, Henk, Decloedt, Eric, Pedro, Maria Rosel, Takeuchi, Hiroyoshi, Tsukahara, Masaru, Gründer, Gerhard, Sagud, Marina, Celofiga, Andreja, Ignjatovic Ristic, Dragana, Ortiz, Bruno Bertolucci, Elkis, Helio, Pacheco Palha, António José, Llerena, Adrián, Fernandez-Egea, Emilio, Siskind, Dan, Weizman, Abraham, Masmoudi, Rim, Mohd Saffian, Shamin, Leung, Jonathan G., Buckley, Peter F., Marder, Stephen R., Citrome, Leslie, Freudenreich, Oliver, Correll, Christoph U., and Müller, Daniel J.

Published
2023
Full Text
View/download PDF

14. Multilayer depressive symptom networks in adults with bodily pain living in precarious housing or homelessness

Author

Jones, Andrea A., primary, Cho, Lianne L., additional, Gicas, Kristina M., additional, Procyshyn, Ric M., additional, Vila-Rodriguez, Fidel, additional, Stubbs, Jacob L., additional, Leonova, Olga, additional, Buchanan, Tari, additional, Thornton, Allen E., additional, Lang, Donna J., additional, MacEwan, G. William, additional, Panenka, William J., additional, Barr, Alasdair M., additional, Field, Thalia S., additional, and Honer, William G., additional

Published
2023
Full Text
View/download PDF

15. Clinical and functional characteristics of young adults living in single room occupancy housing : preliminary findings from a 10-year longitudinal study

Author

Barbic, Skye P., Jones, Andrea A., Woodward, Melissa, Piercy, Matt, Mathias, Steve, Vila-Rodriguez, Fidel, Leonova, Olga, Smith, Geoffrey N., Buchanan, Tari, Vertinsky, Alexandra T., Gillingham, Stephanie, Panenka, William J., Rauscher, Alexander, Barr, Alasdair M., Procyshyn, Ric M., MacEwan, G. William, Lang, Donna J., Thornton, Allen E., Heran, Manraj K., Leon, Adelena M., Krausz, Michael, and Honer, William G.

Published
2018

19. Clozapine ultrarapid metabolism during weak induction probably exists but requires careful diagnosis. A literature review, five new cases and a proposed definition

Author

Schoretsanitis, Georgios, primary, Anıl Yağcıoğlu, A. Elif, additional, Ruan, Can-Jun, additional, Eap, Chin B., additional, Molden, Espen, additional, Baptista, Trino, additional, Clark, Scott R., additional, Fernandez-Egea, Emilio, additional, Kim, Se Hyun, additional, Lane, Hsien-Yuan, additional, Leung, Jonathan, additional, Maroñas Amigo, Olalla, additional, Motuca, Mariano, additional, Olmos, Ismael, additional, Every-Palmer, Susanna, additional, Procyshyn, Ric M., additional, Rohde, Christopher, additional, Satish, Suhas, additional, Schulte, Peter F.J., additional, Spina, Edoardo, additional, Takeuchi, Hiroyoshi, additional, Verdoux, Hélène, additional, Correll, Christoph U., additional, and de Leon, Jose, additional

Published
2023
Full Text
View/download PDF

27. Associations of substance use, psychosis, and mortality among people living in precarious housing or homelessness: A longitudinal, community-based study in Vancouver, Canada

Author

Jones, Andrea A., Gicas, Kristina M., Seyedin, Sam, Willi, Taylor S., Leonova, Olga, Vila-Rodriguez, Fidel, Procyshyn, Ric M., Smith, Geoffrey N., Schmitt, Toby A., Vertinsky, A. Talia, Buchanan, Tari, Rauscher, Alex, Lang, Donna J., MacEwan, G. William, Lima, Viviane D., Montaner, Julio S. G., Panenka, William J., Barr, Alasdair M., Thornton, Allen E., and Honer, William G.

Subjects
Marijuana -- Analysis -- Health aspects, Methamphetamine -- Health aspects -- Analysis, Alcoholism -- Risk factors, Cocaine -- Analysis -- Health aspects, Homelessness -- Analysis -- Health aspects, Social services -- Analysis -- Health aspects, Opioids -- Analysis -- Health aspects, Biological sciences
Abstract

Background The 'trimorbidity' of substance use disorder and mental and physical illness is associated with living in precarious housing or homelessness. The extent to which substance use increases risk of psychosis and both contribute to mortality needs investigation in longitudinal studies. Methods and findings A community-based sample of 437 adults (330 men, mean [SD] age 40.6 [11.2] years) living in Vancouver, Canada, completed baseline assessments between November 2008 and October 2015. Follow-up was monthly for a median 6.3 years (interquartile range 3.1-8.6). Use of tobacco, alcohol, cannabis, cocaine, methamphetamine, and opioids was assessed by interview and urine drug screen; severity of psychosis was also assessed. Mortality (up to November 15, 2018) was assessed from coroner's reports and hospital records. Using data from monthly visits (mean 9.8, SD 3.6) over the first year after study entry, mixed-effects logistic regression analysis examined relationships between risk factors and psychotic features. A past history of psychotic disorder was common (60.9%). Nonprescribed substance use included tobacco (89.0%), alcohol (77.5%), cocaine (73.2%), cannabis (72.8%), opioids (51.0%), and methamphetamine (46.5%). During the same year, 79.3% of participants reported psychotic features at least once. Greater risk was associated with number of days using methamphetamine (adjusted odds ratio [aOR] 1.14, 95% confidence interval [CI] 1.05-1.24, p = 0.001), alcohol (aOR 1.09, 95% CI 1.01-1.18, p = 0.04), and cannabis (aOR 1.08, 95% CI 1.02-1.14, p = 0.008), adjusted for demographic factors and history of past psychotic disorder. Greater exposure to concurrent month trauma was associated with increased odds of psychosis (adjusted model aOR 1.54, 95% CI 1.19-2.00, p = 0.001). There was no evidence for interactions or reverse associations between psychotic features and time-varying risk factors. During 2,481 total person years of observation, 79 participants died (18.1%). Causes of death were physical illness (40.5%), accidental overdose (35.4%), trauma (5.1%), suicide (1.3%), and unknown (17.7%). A multivariable Cox proportional hazard model indicated baseline alcohol dependence (adjusted hazard ratio [aHR] 1.83, 95% CI 1.09-3.07, p = 0.02), and evidence of hepatic fibrosis (aHR 1.81, 95% CI 1.08-3.03, p = 0.02) were risk factors for mortality. Among those under age 55 years, a history of a psychotic disorder was a risk factor for mortality (aHR 2.38, 95% CI 1.03-5.51, p = 0.04, adjusted for alcohol dependence at baseline, human immunodeficiency virus [HIV], and hepatic fibrosis). The primary study limitation concerns generalizability: conclusions from a community-based, diagnostically heterogeneous sample may not apply to specific diagnostic groups in a clinical setting. Because one-third of participants grew up in foster care or were adopted, useful family history information was not obtainable. Conclusions In this study, we found methamphetamine, alcohol, and cannabis use were associated with higher risk for psychotic features, as were a past history of psychotic disorder, and experiencing traumatic events. We found that alcohol dependence, hepatic fibrosis, and, only among participants, Author(s): Andrea A. Jones 1, Kristina M. Gicas 1, Sam Seyedin 1, Taylor S. Willi 1, Olga Leonova 1, Fidel Vila-Rodriguez 1, Ric M. Procyshyn 1, Geoffrey N. Smith 1, [...]

Published
2020
Full Text
View/download PDF

28. Population pharmacokinetics and dosing of long-acting injectable antipsychotics

Author

Kim, David D., Barr, Alasdair M., Rafizadeh, Reza, and Procyshyn, Ric M.

Subjects
Aripiprazole -- Dosage and administration, Pharmacokinetics -- Methods, Schizophrenia -- Drug therapy, Health, Psychology and mental health
Abstract

A 29-year-old man with schizophrenia treated with aripiprazole 15 mg/d visited his psychiatrist accompanied by his mother, who mentioned that although her son is doing well, she must remind him [...]

Published
2021
Full Text
View/download PDF

38. An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels

Author

de Leon, Jose, Schoretsanitis, Georgios, Smith, Robert L., Molden, Espen, Solismaa, Anssi, Seppala, Niko, Kopecek, Miloslav, Svancer, Patrik, Olmos, Ismael, Ricciardi, Carina, Iglesias-Garcia, Celso, Iglesias-Alonso, Ana, Spina, Edoardo, Ruan, Can-Jun, Wang, Chuan-Yue, Wang, Gang, Tang, Yi-Lang, Lin, Shih-Ku, Lane, Hsien-Yuan, Kim, Yong Sik, Kim, Se Hyun, Rajkumar, Anto P., Gonzalez-Esquivel, Dinora F., Jung-Cook, Helgi, Baptista, Trino, Rohde, Christopher, Nielsen, Jimmi, Verdoux, Helene, Quiles, Clelia, Sanz, Emilio J., De las Cuevas, Carlos, Cohen, Dan, Schulte, Peter F. J., Ertugrul, Aygun, Chopra, Nitin, McCollum, Betsy, Shelton, Charles, Cotes, Robert O., Kaithi, Arun R., Kane, John M., Farooq, Saeed, Ng, Chee H., Bilbily, John, Hiemke, Christoph, Lopez-Jaramillo, Carlos, McGrane, Ian, Lana, Fernando, Eap, Chin B., Arrojo-Romero, Manuel, Seifritz, Erich, Every-Palmer, Susanna, Bousman, Chad A., Bebawi, Emmanuel, Bhattacharya, Rahul, Kelly, Deanna L., Otsuka, Yuji, Lazary, Judit, Torres, Rafael, Yecora, Agustin, Motuca, Mariano, Chan, Sherry K. W., Zolezzi, Monica, Ouanes, Sami, De Berardis, Domenico, Grover, Sandeep, Procyshyn, Ric M., Adebayo, Richard A., Kirilochev, Oleg O., Soloviev, Andrey, Fountoulakis, Konstantinos N., Wilkowska, Alina, Ayub, Muhammad, Silva, Alzira, Bonelli, Raphael M., Villagran-Moreno, Jose M., Crespo-Facorro, Benedicto, Temmingh, Henk, Decloedt, Eric, Pedro, Maria R., Takeuchi, Hiroyoshi, Tsukahara, Masaru, Gruender, Gerhard, Sagud, Marina, Celofiga, Andreja, Ristic, Dragana Ignjatovic, Ortiz, Bruno B., Elkis, Helio, Palha, Antonio J. Pacheco, LLerena, Adrian, Fernandez-Egea, Emilio, Siskind, Dan, Weizman, Abraham, Masmoudi, Rim, Saffian, Shamin Mohd, Leung, Jonathan G., Buckley, Peter F., Marder, Stephen R., Citrome, Leslie, Freudenreich, Oliver, Correll, Christoph U., Muller, Daniel J., Anil Yagcioglu, A. Elif, Radulescu, Flavian S., Cubala, Wieslaw J., de Leon, Jose, Schoretsanitis, Georgios, Smith, Robert L., Molden, Espen, Solismaa, Anssi, Seppala, Niko, Kopecek, Miloslav, Svancer, Patrik, Olmos, Ismael, Ricciardi, Carina, Iglesias-Garcia, Celso, Iglesias-Alonso, Ana, Spina, Edoardo, Ruan, Can-Jun, Wang, Chuan-Yue, Wang, Gang, Tang, Yi-Lang, Lin, Shih-Ku, Lane, Hsien-Yuan, Kim, Yong Sik, Kim, Se Hyun, Rajkumar, Anto P., Gonzalez-Esquivel, Dinora F., Jung-Cook, Helgi, Baptista, Trino, Rohde, Christopher, Nielsen, Jimmi, Verdoux, Helene, Quiles, Clelia, Sanz, Emilio J., De las Cuevas, Carlos, Cohen, Dan, Schulte, Peter F. J., Ertugrul, Aygun, Chopra, Nitin, McCollum, Betsy, Shelton, Charles, Cotes, Robert O., Kaithi, Arun R., Kane, John M., Farooq, Saeed, Ng, Chee H., Bilbily, John, Hiemke, Christoph, Lopez-Jaramillo, Carlos, McGrane, Ian, Lana, Fernando, Eap, Chin B., Arrojo-Romero, Manuel, Seifritz, Erich, Every-Palmer, Susanna, Bousman, Chad A., Bebawi, Emmanuel, Bhattacharya, Rahul, Kelly, Deanna L., Otsuka, Yuji, Lazary, Judit, Torres, Rafael, Yecora, Agustin, Motuca, Mariano, Chan, Sherry K. W., Zolezzi, Monica, Ouanes, Sami, De Berardis, Domenico, Grover, Sandeep, Procyshyn, Ric M., Adebayo, Richard A., Kirilochev, Oleg O., Soloviev, Andrey, Fountoulakis, Konstantinos N., Wilkowska, Alina, Ayub, Muhammad, Silva, Alzira, Bonelli, Raphael M., Villagran-Moreno, Jose M., Crespo-Facorro, Benedicto, Temmingh, Henk, Decloedt, Eric, Pedro, Maria R., Takeuchi, Hiroyoshi, Tsukahara, Masaru, Gruender, Gerhard, Sagud, Marina, Celofiga, Andreja, Ristic, Dragana Ignjatovic, Ortiz, Bruno B., Elkis, Helio, Palha, Antonio J. Pacheco, LLerena, Adrian, Fernandez-Egea, Emilio, Siskind, Dan, Weizman, Abraham, Masmoudi, Rim, Saffian, Shamin Mohd, Leung, Jonathan G., Buckley, Peter F., Marder, Stephen R., Citrome, Leslie, Freudenreich, Oliver, Correll, Christoph U., Muller, Daniel J., Anil Yagcioglu, A. Elif, Radulescu, Flavian S., and Cubala, Wieslaw J.

Abstract

This international guideline proposes improving clozapine package inserts worldwide by using ancestry-based dosing and titration. Adverse drug reaction (ADR) databases suggest that clozapine is the third most toxic drug in the United States (US), and it produces four times higher worldwide pneumonia mortality than that by agranulocytosis or myocarditis. For trough steady-state clozapine serum concentrations, the therapeutic reference range is narrow, from 350 to 600 ng/mL with the potential for toxicity and ADRs as concentrations increase. Clozapine is mainly metabolized by CYP1A2 (female non-smokers, the lowest dose; male smokers, the highest dose). Poor metabolizer status through phenotypic conversion is associated with co-prescription of inhibitors (including oral contraceptives and valproate), obesity, or inflammation with C-reactive protein (CRP) elevations. The Asian population (Pakistan to Japan) or the Americas' original inhabitants have lower CYP1A2 activity and require lower clozapine doses to reach concentrations of 350 ng/mL. In the US, daily doses of 300-600 mg/day are recommended. Slow personalized titration may prevent early ADRs (including syncope, myocarditis, and pneumonia). This guideline defines six personalized titration schedules for inpatients: 1) ancestry from Asia or the original people from the Americas with lower metabolism (obesity or valproate) needing minimum therapeutic dosages of 75-150 mg/day, 2) ancestry from Asia or the original people from the Americas with average metabolism needing 175-300 mg/day, 3) European/Western Asian ancestry with lower metabolism (obesity or valproate) needing 100-200 mg/day, 4) European/Western Asian ancestry with average metabolism needing 250-400 mg/day, 5) in the US with ancestries other than from Asia or the original people from the Americas with lower clozapine metabolism (obesity or valproate) needing 150-300 mg/day, and 6) in the US with ancestries other than from Asia or the original people fr

Published
2022

42. Structural Brain Markers Are Differentially Associated With Neurocognitive Profiles in Socially Marginalized People With Multimorbid Illness

Author

Gicas, Kristina M., Giesbrecht, Chantelle J., Panenka, William J., Lang, Donna J., Smith, Geoffrey N., Vila-Rodriguez, Fidel, Leonova, Olga, Jones, Andrea A., Barr, Alasdair M., Procyshyn, Ric M., Buchanan, Tari, MacEwan, G. William, Su, Wayne, Vertinsky, A. Talia, Rauscher, Alexander, Honer, William G., and Thornton, Allen E.

Published
2017
Full Text
View/download PDF

43. Pain, opioid use, depressive symptoms, and mortality in adults living in precarious housing or homelessness: a longitudinal prospective study

Author

Jones, Andrea A., primary, Cho, Lianne L., additional, Kim, David D., additional, Barbic, Skye P., additional, Leonova, Olga, additional, Byford, Alexandra, additional, Buchanan, Tari, additional, Vila-Rodriguez, Fidel, additional, Procyshyn, Ric M., additional, Lang, Donna J., additional, Vertinsky, A. Talia, additional, MacEwan, G. William, additional, Rauscher, Alexander, additional, Panenka, William J., additional, Thornton, Allen E., additional, Barr, Alasdair M., additional, Field, Thalia S., additional, and Honer, William G., additional

Published
2022
Full Text
View/download PDF

45. Correction: An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels

Author

de Leon, Jose, additional, Schoretsanitis, Georgios, additional, Smith, Robert L., additional, Molden, Espen, additional, Solismaa, Anssi, additional, Seppälä, Niko, additional, Kopeček, Miloslav, additional, Švancer, Patrik, additional, Olmos, Ismael, additional, Ricciardi, Carina, additional, Iglesias-Garcia, Celso, additional, Iglesias-Alonso, Ana, additional, Spina, Edoardo, additional, Ruan, Can-Jun, additional, Wang, Chuan-Yue, additional, Wang, Gang, additional, Tang, Yi-Lang, additional, Lin, Shih-Ku, additional, Lane, Hsien-Yuan, additional, Kim, Yong Sik, additional, Kim, Se Hyun, additional, Rajkumar, Anto P., additional, González-Esquivel, Dinora F., additional, Jung-Cook, Helgi, additional, Baptista, Trino, additional, Rohde, Christopher, additional, Nielsen, Jimmi, additional, Verdoux, Hélène, additional, Quiles, Clelia, additional, Sanz, Emilio J., additional, De Las Cuevas, Carlos, additional, Cohen, Dan, additional, Schulte, Peter F.J., additional, Ertuğrul, Aygün, additional, Anıl Yağcıoğlu, A. Elif, additional, Chopra, Nitin, additional, McCollum, Betsy, additional, Shelton, Charles, additional, Cotes, Robert O., additional, Kaithi, Arun R., additional, Kane, John M., additional, Farooq, Saeed, additional, Ng, Chee H., additional, Bilbily, John, additional, Hiemke, Christoph, additional, López-Jaramillo, Carlos, additional, McGrane, Ian, additional, Lana, Fernando, additional, Eap, Chin B., additional, Arrojo-Romero, Manuel, additional, Rădulescu, Flavian Ş., additional, Seifritz, Erich, additional, Every-Palmer, Susanna, additional, Bousman, Chad A., additional, Bebawi, Emmanuel, additional, Bhattacharya, Rahul, additional, Kelly, Deanna L., additional, Otsuka, Yuji, additional, Lazary, Judit, additional, Torres, Rafael, additional, Yecora, Agustin, additional, Motuca, Mariano, additional, Chan, Sherry K.W., additional, Zolezzi, Monica, additional, Ouanes, Sami, additional, De Berardis, Domenico, additional, Grover, Sandeep, additional, Procyshyn, Ric M., additional, Adebayo, Richard A., additional, Kirilochev, Oleg O., additional, Soloviev, Andrey, additional, Fountoulakis, Konstantinos N., additional, Wilkowska, Alina, additional, Cubała, Wiesław J., additional, Ayub, Muhammad, additional, Silva, Alzira, additional, Bonelli, Raphael M., additional, Villagrán-Moreno, José M., additional, Crespo-Facorro, Benedicto, additional, Temmingh, Henk, additional, Decloedt, Eric, additional, Pedro, Maria R., additional, Takeuchi, Hiroyoshi, additional, Tsukahara, Masaru, additional, Gründer, Gerhard, additional, Sagud, Marina, additional, Celofiga, Andreja, additional, Ignjatovic Ristic, Dragana, additional, Ortiz, Bruno B., additional, Elkis, Helio, additional, Pacheco Palha, António J., additional, LLerena, Adrián, additional, Fernandez-Egea, Emilio, additional, Siskind, Dan, additional, Weizman, Abraham, additional, Masmoudi, Rim, additional, Mohd Saffian, Shamin, additional, Leung, Jonathan G., additional, Buckley, Peter F., additional, Marder, Stephen R., additional, Citrome, Leslie, additional, Freudenreich, Oliver, additional, Correll, Christoph U., additional, and Müller, Daniel J., additional

Published
2022
Full Text
View/download PDF

47. An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels

Author

de Leon, Jose, additional, Schoretsanitis, Georgios, additional, Smith, Robert L., additional, Molden, Espen, additional, Solismaa, Anssi, additional, Seppälä, Niko, additional, Kopeček, Miloslav, additional, Švancer, Patrik, additional, Olmos, Ismael, additional, Ricciardi, Carina, additional, Iglesias-Garcia, Celso, additional, Iglesias-Alonso, Ana, additional, Spina, Edoardo, additional, Ruan, Can-Jun, additional, Wang, Chuan-Yue, additional, Wang, Gang, additional, Tang, Yi-Lang, additional, Lin, Shih-Ku, additional, Lane, Hsien-Yuan, additional, Kim, Yong Sik, additional, Kim, Se Hyun, additional, Rajkumar, Anto P., additional, González-Esquivel, Dinora F., additional, Jung-Cook, Helgi, additional, Baptista, Trino, additional, Rohde, Christopher, additional, Nielsen, Jimmi, additional, Verdoux, Hélène, additional, Quiles, Clelia, additional, Sanz, Emilio J., additional, De Las Cuevas, Carlos, additional, Cohen, Dan, additional, Schulte, Peter F.J., additional, Ertuğrul, Aygün, additional, Anıl Yağcıoğlu, A. Elif, additional, Chopra, Nitin, additional, McCollum, Betsy, additional, Shelton, Charles, additional, Cotes, Robert O., additional, Kaithi, Arun R., additional, Kane, John M., additional, Farooq, Saeed, additional, Ng, Chee H., additional, Bilbily, John, additional, Hiemke, Christoph, additional, López-Jaramillo, Carlos, additional, McGrane, Ian, additional, Lana, Fernando, additional, Eap, Chin B., additional, Arrojo-Romero, Manuel, additional, Rădulescu, Flavian Ş., additional, Seifritz, Erich, additional, Every-Palmer, Susanna, additional, Bousman, Chad A., additional, Bebawi, Emmanuel, additional, Bhattacharya, Rahul, additional, Kelly, Deanna L., additional, Otsuka, Yuji, additional, Lazary, Judit, additional, Torres, Rafael, additional, Yecora, Agustin, additional, Motuca, Mariano, additional, Chan, Sherry K.W., additional, Zolezzi, Monica, additional, Ouanes, Sami, additional, De Berardis, Domenico, additional, Grover, Sandeep, additional, Procyshyn, Ric M., additional, Adebayo, Richard A., additional, Kirilochev, Oleg O., additional, Soloviev, Andrey, additional, Fountoulakis, Konstantinos N., additional, Wilkowska, Alina, additional, Cubała, Wiesław J., additional, Ayub, Muhammad, additional, Silva, Alzira, additional, Bonelli, Raphael M., additional, Villagrán-Moreno, José M., additional, Crespo-Facorro, Benedicto, additional, Temmingh, Henk, additional, Decloedt, Eric, additional, Pedro, Maria R., additional, Takeuchi, Hiroyoshi, additional, Tsukahara, Masaru, additional, Gründer, Gerhard, additional, Sagud, Marina, additional, Celofiga, Andreja, additional, Ignjatovic Ristic, Dragana, additional, Ortiz, Bruno B., additional, Elkis, Helio, additional, Pacheco Palha, António J., additional, LLerena, Adrián, additional, Fernandez-Egea, Emilio, additional, Siskind, Dan, additional, Weizman, Abraham, additional, Masmoudi, Rim, additional, Mohd Saffian, Shamin, additional, Leung, Jonathan G., additional, Buckley, Peter F., additional, Marder, Stephen R., additional, Citrome, Leslie, additional, Freudenreich, Oliver, additional, Correll, Christoph U., additional, and Müller, Daniel J., additional

Published
2021
Full Text
View/download PDF

49. Dynamic networks of psychotic symptoms in adults living in precarious housing or homelessness.

Author

Jones, Andrea A., Gicas, Kristina M., Mostafavi, Sara, Woodward, Melissa L., Leonova, Olga, Vila-Rodriguez, Fidel, Procyshyn, Ric M., Cheng, Alex, Buchanan, Tari, Lang, Donna J., MacEwan, G. William, Panenka, William J., Barr, Alasdair M., Thornton, Allen E., and Honer, William G.

Subjects
MORTALITY risk factors, DRUG addiction, PSYCHOSES, MULTIPLE regression analysis, FUNCTIONAL connectivity, SEVERITY of illness index, METHAMPHETAMINE, PSYCHOSOCIAL factors, HOMELESS persons, HOMELESSNESS, WOUNDS & injuries, PROPORTIONAL hazards models, EVALUATION, ADULTS
Abstract

Background: People living in precarious housing or homelessness have higher than expected rates of psychotic disorders, persistent psychotic symptoms, and premature mortality. Psychotic symptoms can be modeled as a complex dynamic system, allowing assessment of roles for risk factors in symptom development, persistence, and contribution to premature mortality. Method: The severity of delusions, conceptual disorganization, hallucinations, suspiciousness, and unusual thought content was rated monthly over 5 years in a community sample of precariously housed/homeless adults (n = 375) in Vancouver, Canada. Multilevel vector auto-regression analysis was used to construct temporal, contemporaneous, and between-person symptom networks. Network measures were compared between participants with (n = 219) or without (n = 156) history of psychotic disorder using bootstrap and permutation analyses. Relationships between network connectivity and risk factors including homelessness, trauma, and substance dependence were estimated by multiple linear regression. The contribution of network measures to premature mortality was estimated by Cox proportional hazard models. Results: Delusions and unusual thought content were central symptoms in the multilevel network. Each psychotic symptom was positively reinforcing over time, an effect most pronounced in participants with a history of psychotic disorder. Global connectivity was similar between those with and without such a history. Greater connectivity between symptoms was associated with methamphetamine dependence and past trauma exposure. Auto-regressive connectivity was associated with premature mortality in participants under age 55. Conclusions: Past and current experiences contribute to the severity and dynamic relationships between psychotic symptoms. Interrupting the self-perpetuating severity of psychotic symptoms in a vulnerable group of people could contribute to reducing premature mortality. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

50. Characterization of Bodily Pain and Use of Both Prescription and Non-Prescription Opioids in Tenants of Precarious Housing

Author

Lei, Michelle, primary, Rintoul, Kathryn, additional, Stubbs, Jacob L., additional, Kim, David D., additional, Jones, Andrea A., additional, Hamzah, Yasmin, additional, Procyshyn, Ric M., additional, Gicas, Kristina M., additional, Cho, Lianne L., additional, Panenka, William J., additional, Thornton, Allen E., additional, Lang, Donna J., additional, MacEwan, G. William, additional, Honer, William G., additional, and Barr, Alasdair M., additional

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results