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1. A two-component response regulator, gltR, is required for glucose transport activity in Pseudomonas aeruginosa PAO1.

Author

Sage AE, Proctor WD, and Phibbs PV Jr

Subjects
Amino Acid Sequence, Biological Transport, Molecular Sequence Data, Mutagenesis, Insertional, Pseudomonas aeruginosa metabolism, Sequence Homology, Amino Acid, Bacterial Proteins genetics, Gene Expression Regulation, Bacterial, Glucose metabolism, Monosaccharide Transport Proteins, Pseudomonas aeruginosa genetics
Abstract

A 729-bp open reading frame (gltR) was identified in Pseudomonas aeruginosa PAO1 that encodes a product homologous to the two-component response regulator family of proteins. Disruption of gltR caused loss of glucose transport activity. Restoration of gltR resulted in wild-type levels of glucose transport. These findings indicate that gltR is required for expression of the glucose transport system in P. aeruginosa.

Published
1996
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