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Abstract: Traditional remedies have been used for generations to treat and maintain people's health and indigenous medicinal plants are an important part of this system, which, unlike western medicine, provides cures for practically all illnesses with no side effects. Such an ulcer is a chronic ailment that affects most of the world's population and has no absolute cure. An ulcer is the erosion of mucous lining in the gastrointestinal tract due to over secretion of HCl in the stomach, leading to inflammation and soreness. Consumption of highly spicy meals, an obese lifestyle, an unplanned diet, the use of excessive non-steroidal anti-inflammatory medicines, smoking, stress, an irregular sleep cycle, and regular alcohol consumption are all possible causes of ulcers. Ayurvedic and traditional medicine practitioners employ a variety of indigenous medicinal plants to cure ulcers. This review covers a wide variety of medicinal plants that may work as anti-ulcer and deserves more investigation.