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1. Successful immunosuppressive drug‐free immune tolerance induction in hemophilia B with inhibitor and anaphylaxis to factor IX: A case report.

Author

Palomo Bravo, Ángeles, Prieto Bonilla, Rosario, Bardan Rebollar, Daniel, López‐Jaime, Francisco José, and Fernández‐Bello, Ihosvany

Subjects
*BLOOD coagulation factor IX, *IMMUNOLOGICAL tolerance, *MEDICAL protocols, *HEMOPHILIA, *ANAPHYLAXIS
Abstract

Key Clinical Message: Recommendations advise factor IX desensitization before immune tolerance induction in severe hemophilia B, supported by immunosuppression. A child with inhibitor and anaphylaxis to factor IX showed successful immunosuppression‐free immune tolerance induction using very low and slowly increasing doses of a factor IX extended‐half‐life product. Immune tolerance to factor IX based on this protocol merits further study. [ABSTRACT FROM AUTHOR]

Published
2024
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