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467 results on '"Prieto, M.A."'

12. Guía práctica sobre el diagnóstico y tratamiento de la hipertensión arterial en España, 2022. Sociedad Española de Hipertensión - Liga Española para la Lucha contra la Hipertensión Arterial (SEH-LELHA)

Author

Gorostidi, M., Gijón-Conde, T., de la Sierra, A., Rodilla, E., Rubio, E., Vinyoles, E., Oliveras, A., Santamaría, R., Segura, J., Molinero, A., Pérez-Manchón, D., Abad, M., Abellán, J., Armario, P., Banegas, J.R., Camafort, M., Catalina, C., Coca, A., Divisón, J.A., Domenech, M., Martell, N., Martín-Rioboó, E., Morales-Olivas, F., Pallarés, V., Pérez de Isla, L., Prieto, M.A., Redón, J., Ruilope, L.M., and García-Donaire, J.A.

Published
2022
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15. Role of leucine zipper-like motifs in the oligomerization of Pseudomonas putida phasins

Author

Tarazona, N.A., Maestro García-Donas, María Beatriz, Revelles, O., Sanz, J.M., Prieto, M.A.., Tarazona, N.A., Maestro García-Donas, María Beatriz, Revelles, O., Sanz, J.M., and Prieto, M.A..

Abstract

Background Phasins are low molecular mass proteins that accumulate strongly in bacterial cells in response to the intracellular storage of polyhydroxyalkanoates (PHA). Although lacking catalytic activity, phasins are the major components of the surface of the PHA granules and could be potentially involved in the formation of a network-like protein layer surrounding the polyester inclusions. Structural models revealed phasins to possess coiled-coil regions that might be important in the establishment of protein-protein interactions. However, there is not experimental evidence of a coiled-coil mediated oligomerization in these proteins. Methods Structure prediction analyses were used to characterize the coiled-coil motifs of phasins PhaF and PhaI –produced by the model bacterium Pseudomonas putida KT2440–. Their oligomerization was evaluated by biolayer interferometry and the in vivo two-hybrid (BACTH) system. The interaction ability of a series of coiled-coil mutated derivatives was also measured. Results The formation of PhaF and PhaI complexes was detected. A predicted short leucine zipper-like coiled-coil (ZIP), containing “ideal” residues located within the hydrophobic core, was shown responsible for the oligomers stability. The substitution of key residues (leucines or valines) in PhaI ZIP (ZIPI) for alanine reduced by four fold the oligomerization efficiency. Conclusions These results indicate that coiled-coil motifs are essential for phasin interactions. Correct oligomerization requires the formation of a stable hydrophobic interface between both phasins. General Significance. Our findings elucidate the oligomerization motif of PhaF and PhaI. This motif is present in most phasins from PHA-accumulating bacteria and offers a potentially important target for modulating the PHA granules stability., Unión Europea, Comunidad de Madrid, Ministerio de Economía, Industria y Competitividad (MINECO), Depto. de Bioquímica y Biología Molecular, Fac. de Ciencias Biológicas, TRUE, pub

Published
2024

25. Frequency of human papillomavirus infection in patients with gastrointestinal cancer

Author

Roesch-Dietlen, F., Cano-Contreras, A.D., Sánchez-Maza, Y.J., Espinosa-González, J.M., Vázquez-Prieto, M.Á., Valdés-de la O, E.J., Díaz-Roesch, F., Carrasco-Arroniz, M.Á., Cruz-Palacios, A., Grube-Pagola, P., Sumoza-Toledo, A., Vivanco-Cid, H., Mellado-Sánchez, G., Meixueiro-Daza, A., Silva-Cañetas, C.S., Carrillo-Toledo, M.G., Lagunes-Torres, R., Amieva-Balmori, M., Gómez-Castaño, P.C., Reyes-Huerta, J.U., and Remes-Troche, J.M.

Published
2018
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26. Frecuencia de infección por virus del papiloma humano en pacientes con cáncer del aparato digestivo

Author

Roesch-Dietlen, F., Cano-Contreras, A.D., Sánchez-Maza, Y.J., Espinosa-González, J.M., Vázquez-Prieto, M.Á., Valdés-de la O, E.J., Díaz-Roesch, F., Carrasco-Arroniz, M.Á., Cruz-Palacios, A., Grube-Pagola, P., Sumoza-Toledo, A., Vivanco-Cid, H., Mellado-Sánchez, G., Meixueiro-Daza, A., Silva-Cañetas, C.S., Carrillo-Toledo, M.G., Lagunes-Torres, R., Amieva-Balmori, M., Gómez-Castaño, P.C., Reyes-Huerta, J.U., and Remes-Troche, J.M.

Published
2018
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27. Description of patients excluded for Mohs surgery after pre-surgical evaluation: data from the Regesmohs Spanish registry

Author

Ruiz-Salas, V., Garcés, J.R., Alonso-Alonso, T., Rodríguez-Prieto, M.A., Toll-Abelló, A., Eusebio Murillo, E., Miñano, R., López-Estebaranz, J.L., Sanmartín-Jiménez, O., Guillén Barona, C., Allende Markixana, I., Alfaro Rubio, A., Delgado Jiménez, Y., Navarro, R., Barchino Ortiz, L., Lázaro Ochaita, P., Vilarasa, E., Ciudad Blanco, C., Vázquez-Veiga, H., Artola Igarza, J.L., Alonso, M.L., García-Doval, I., Descalzo, M.A., and Redondo Bellón, P.

Published
2018
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28. Descripción de pacientes no aptos para ser sometidos a cirugía de Mohs tras valoración prequirúrgica: datos del registro español Regesmohs

Author

Ruiz-Salas, V., Garcés, J.R., Alonso-Alonso, T., Rodríguez-Prieto, M.A., Toll-Abelló, A., Eusebio Murillo, E., Miñano, R., López-Estebaranz, J.L., Sanmartín-Jiménez, O., Guillén Barona, C., Allende Markixana, I., Alfaro Rubio, A., Delgado Jiménez, Y., Navarro, R., Barchino Ortiz, L., Lázaro Ochaita, P., Vilarasa, E., Ciudad Blanco, C., Vázquez-Veiga, H., Artola Igarza, J.L., Alonso, M.L., García-Doval, I., Descalzo, M.A., and Redondo Bellón, P.

Published
2018
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30. Acute generalized exanthematous pustulosis due to dextromethorphan

Author

Otero Rivas, M.M., Sanchez Sambucety, P., Garcia-Ruiz de Morales, J.M., Perez Paredes, G., and Rodriguez Prieto, M.A.

Subjects
Acute Generalized Exanthematous Pustulosis, immunology, dextromethorphan, antitussive agents, drug eruptions.
Abstract

Acute generalized exanthematous pustulosis (AGEP) is a rare, severe, pustular, cutaneous reaction. We report a case in which a patient developed AGEP after the intake of 3 different antitussive agents containing dextromethorphan as the only ingredient in common.

Published
2013

32. Characterization of Surgical Procedures in the Spanish Mohs Surgery Registry (REGESMOHS) for 2013-2015

Author

de Eusebio Murillo, E., Martín Fuentes, A., Ruiz-Salas, V., Garcés, J.R., Miñano Medrano, R., López-Estebaranz, J.L., Alonso-Alonso, T., Rodríguez-Prieto, M.Á., Delgado Jiménez, Y., Morales, V., Redondo Bellón, P., Manubens-Mercadé, E., Sanmartín-Jiménez, O., Guillén Barona, C., Cabeza, R., Cano, N., Toll-Abelló, A., Navarro Tejedor, R., Artola Igarza, J.L., Allende Markixana, I., Alfaro Rubio, A., Ciudad Blanco, C., Vázquez-Veiga, H., Barchino Ortiz, L., Descalzo, M.A., and García-Doval, I.

Published
2017
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33. Descripción de las intervenciones quirúrgicas recogidas en el registro español de cirugía de Mohs (REGESMOHS) (2013-2015)

Author

de Eusebio Murillo, E., Martín Fuentes, A., Ruiz-Salas, V., Garcés, J.R., Miñano Medrano, R., López-Estebaranz, J.L., Alonso-Alonso, T., Rodríguez-Prieto, M.Á., Delgado Jiménez, Y., Morales, V., Redondo Bellón, P., Manubens-Mercadé, E., Sanmartín-Jiménez, O., Guillén Barona, C., Cabeza, R., Cano, N., Toll-Abelló, A., Navarro Tejedor, R., Artola Igarza, J.L., Allende Markixana, I., Alfaro Rubio, A., Ciudad Blanco, C., Vázquez-Veiga, H., Barchino Ortiz, L., Descalzo, M.A., and García-Doval, I.

Published
2017
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43. Biological Functions and Utilization of Different Part of the Papaya: A Review.

Author

Jiao, Mingyue, Liu, Chao, Prieto, M.A., Lu, Xiaoming, Wu, Wenfu, Sun, Jinyue, García-Oliveira, P., Tang, Xiaozhen, Xiao, Jianbo, Simal-Gandara, Jesus, Hu, Dagang, and Li, Ningyang

Subjects
PAPAYA, FOOD industry, FRUIT trees, NUTRITIONAL value
Abstract

Papaya is one of the most important fruit trees cultivated throughout the tropical and subtropical regions and its production is rising worldwide. Its edible part has a high nutritional and sensory value and a great commercial potential. Mature papaya is consumed fresh and has been used in food processing and cosmetic industries. Along with some other parts such as leaves, seeds or skin, papaya has been used in traditional medicine in various countries. In fact, numerous studies have reported the presence of bioactive compounds with diverse biological properties in the papaya by-products, which has motivated the expansion of their applications. Papaya by-products have been demonstrated to exert a wide range of activities (e.g.; antioxidant, anti-cancer, anti-dengue, anti-malarial, anti-fertility, diabetes prevention, insecticidal, anti-AIDS) that could be useful in pharmaceutical industry. They could be used in food industry, as a source of functional compounds and in innovative active packaging strategies, and in different cosmetic products, among other applications. Although this scenario indicates that the papaya industry could diversify and increase its economic value, there are two problems that significantly affect it: the spread of pathogens and the highly perishable nature of this fruit. On the one hand, genetic tools have been used to obtain transgenic varieties resistant to pathogens, while new preservation technologies have been explored. This review focuses on the main bioactive compounds, important physiological functions and applications of different papaya parts and also in the current development of genetically modified papaya in the industry and the research progress on storage and preservation. [ABSTRACT FROM AUTHOR]

Published
2023
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44. The Nutritional and Bioactive Components, Potential Health Function and Comprehensive Utilization of Pomegranate: A Review.

Author

Yang, Xuhan, Niu, Zhonglu, Wang, Xiaorui, Lu, Xiaoming, Sun, Jinyue, Carpena, M., Prieto, M.A., Simal-Gandara, Jesus, Xiao, Jianbo, Liu, Chao, and Li, Ningyang

Subjects
POMEGRANATE, BIOACTIVE compounds, ELLAGITANNINS, UNSATURATED fatty acids, CULTIVARS, GERMPLASM, SKIN care
Abstract

Pomegranate is native to the region between Iran and northern India, as well as cultivated in China with a large planting area and a variety of high-quality species. Pomegranate not only has delicious fruits and beautiful flowers, but it is rich in bioactive compounds with benefits to human health.The distribution and content of bioactive components in different organs and by-products of pomegranate have distinct characteristics. A variety of phenols, flavonoids, and triterpenoids exist in pomegranate peels and flowers, whereas the active ingredients in the leaves are mainly tannins. Arils and seeds are good sources of anthocyanins and unsaturated fatty acids, respectively. Pomegranate possesses antioxidant, anti-inflammatory, anti-cancer, anti-diabetic, anti-cardiovascular, anti-pathogenic and skin care effects, among others. It is also widely used in food, health care, medicinal, and ornamental purposes. This review summarizes recent research progress on pomegranate, putting forward some innovative applications for the development and utilization of pomegranate resources. This review also provides a theoretical basis for the research and industrialization of pomegranate, as well as a reference for further development of pomegranate germplasm resources. [ABSTRACT FROM AUTHOR]

Published
2023
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46. Description of Patients Undergoing Mohs Surgery in Spain: Initial Report on Data From the Spanish Registry of Mohs Surgery (REGESMOHS)

Author

Ruiz-Salas, V., Garcés, J.R., Miñano Medrano, R., Alonso-Alonso, T., Rodríguez-Prieto, M.Á., López-Estebaranz, J.L., Sanmartín-Jiménez, O., Guillén Barona, C., Delgado Jiménez, Y., Toll-Abelló, A., Vargas Diez, E., Ciudad Blanco, C., Alfaro Rubio, A., Allende Markixana, I., de Eusebio Murillo, E., Manubens-Mercadé, E., Vázquez-Veiga, H., Barchino Ortiz, L., García-Doval, I., and Redondo Bellón, P.

Published
2015
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47. Descripción de los pacientes intervenidos mediante cirugía de Mohs en España. Datos basales del registro español de cirugía de Mohs (REGESMOHS)

Author

Ruiz-Salas, V., Garcés, J.R., Miñano Medrano, R., Alonso-Alonso, T., Rodríguez-Prieto, M.Á., López-Estebaranz, J.L., Sanmartín-Jiménez, O., Guillén Barona, C., Delgado Jiménez, Y., Toll-Abelló, A., Vargas Diez, E., Ciudad Blanco, C., Alfaro Rubio, A., Allende Markixana, I., de Eusebio Murillo, E., Manubens-Mercadé, E., Vázquez-Veiga, H., Barchino Ortiz, L., García-Doval, I., and Redondo Bellón, P.

Published
2015
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