Search

Air pollution due to dust emission is continuously increasing day by day in mining and allied industrial areas. Mining operations contribute a substantial amount of dust emission at the crushing, screening, and bulk material handling in loading areas. The ambient suspended dust particles create a severe nuisance to workers and local dwellers. For effective controlling of positive dust emission, an innovative automated dry fog dust suppression system (DFDSS) has been developed using hybrid nozzles, sensors, actuators, controllers, screw compressors, air receivers, pumps, motors, and water arrangement with filtration facility. The DFDSS was installed in a crushing and screening plant of an iron ore mine in India. Performance study indicted fugitive dust emission concentration values ranged from 354 to 7040 μg m -3 , which was reduced to 91-300 μg m -3 after installation of DFDSS. The reduced values were within the permissible limit of 1200 μg m -3 at a distance of 25 ± 2 m in the predominant downwind direction. The installed DFDSS added a meager addition of moisture content of 0.032% in the handling iron ore material, which was below the acceptable limit of 0.1%. The DFDSS precisely regulated fugitive dust emission from various mining activities without affecting the minerals processing performance. Thus, the DFDSS can be implemented effectively in different mining and allied industries where there is a dust emission problem., (Copyright © 2021 Elsevier Ltd. All rights reserved.)

Objective: Evidence suggests prolonged exposure to lower levels of low-density lipoprotein cholesterol (LDL-C), starting at a younger age, substantially lowers cardiovascular (CV) risk. Accordingly, the CV pandemic affecting younger population in low- to low-middle-income countries, where statin usage is poor even in secondary prevention, may benefit from lipid-lowering nutritional products, as nutritional intervention is generally preferred in these cultures. However, the safety and efficacy of such preparations have not been systematically tested., Methods: In this multicenter, double-blind study, 191 statin-free subjects with newly-diagnosed hyperlipidemia (LDL-C >120 mg/dL, 3.11 mmol/L) and no evidence of CV disease were randomized to one capsule of a proprietary bioactive phytonutrient formulation containing red yeast rice, grape-seed, niacinamide, and folic acid (RYR-NS) or matched placebo twice daily, along with lifestyle modification, for 12 wk., Results: Mean baseline LDL-C levels were 148.5 ± 24.0 mg/dL (3.85 ± 0.62 mmol/L) and 148.6 ± 21.9 mg/dL (3.85 ± 0.57 mmol/L) in the RYR-NS and placebo groups respectively. Compared with placebo, RYR-NS resulted in a significant reduction in LDL-C (-29.4% versus -3.5%, P < 0.0001) and non-high-density lipoprotein cholesterol (non-HDL-C; -29.8% versus -10.3%, P < 0.0001) at 12 wk. With RYR-NS, 43.4% individuals attained desirable LDL-C levels and 55.4% desirable non-HDL-C levels by week 12, compared to only 0% and 1.1%, respectively, at baseline. No safety issues were observed., Conclusion: This study demonstrates the efficacy and safety of RYR-NS in lowering LDL-C and non-HDL-C after 12 wk, with magnitude of LDL-C reduction being comparable to that seen with moderate-intensity statin therapy. Further long-term studies are required to determine the impact of RYR-NS on treatment adherence and clinical outcomes., (Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.)

Cucumis melo L. that belongs to Cucurbitaceae family ranks among one of the highest valued horticulture crops being cultivated across the globe. Besides its economical and medicinal importance, Cucumis melo L. is a valuable resource and model system for the evolutionary studies of cucurbit family. However, very limited numbers of molecular markers were reported for Cucumis melo L. so far that limits the pace of functional genomic research in melon and other similar horticulture crops. We developed the first whole genome based microsatellite DNA marker database of Cucumis melo L. and comprehensive web resource that aids in variety identification and physical mapping of Cucurbitaceae family. The Cucumis melo L. microsatellite database (CmMDb: http://65.181.125.102/cmmdb2/index.html) encompasses 39,072 SSR markers along with its motif repeat, motif length, motif sequence, marker ID, motif type and chromosomal locations. The database is featured with novel automated primer designing facility to meet the needs of wet lab researchers. CmMDb is a freely available web resource that facilitates the researchers to select the most appropriate markers for marker-assisted selection in melons and to improve breeding strategies.

Nonhealing neuropathic foot ulcers remain a significant problem in individuals with diabetes. The gap-junctional protein connexin43 (Cx43) has roles in dermal wound healing and targeting Cx43 signalling accelerates wound reepithelialization. In a prospective, randomized, multicenter clinical trial we evaluated the efficacy and safety of a peptide mimetic of the C-terminus of Cx43, alpha connexin carboxy-terminal (ACT1), in accelerating the healing of chronic diabetic foot ulcers (DFUs) when incorporated into standard of care (SOC) protocols. Adults with DFUs of at least four weeks duration were randomized to receive SOC with or without topical application of ACT1. Primary outcome was mean percent ulcer reepithelialization and safety variables included incidence of treatment related adverse events (AEs) and detection of ACT1 immunogenicity. ACT1 treatment was associated with a significantly greater reduction in mean percent ulcer area from baseline to 12 weeks (72.1% vs. 57.1%; p = 0.03). Analysis of incidence and median time-to-complete-ulcer closure revealed that ACT1 treatment was associated with a greater percentage of participants that reached 100% ulcer reepitheliazation and a reduced median time-to-complete-ulcer closure. No AEs reported were treatment related, and ACT1 was not immunogenic. Treatment protocols that incorporate ACT1 may present a therapeutic strategy that safely augments the reepithelialization of chronic DFUs., (© 2015 Authors. Wound Repair and Regeneration published by Wiley Periodicals, Inc. on behalf of The Wound Healing Society.)

Objectives: The purpose of this study was to assess the attitude of dental students towards considering Public Health Dentistry as their future career., Materials and Methods: A questionnaire based, cross-sectional survey was conducted, which included dental students from different years of study. It consisted of 27 questions that were graded on five point Likert scale., Results: A total of 293 of the 320 registered undergraduate students participated in the study, with an overall response rate of 91.5%. Among the sample, 80 (27%) were males and 213 (73%) were females. Among the total sample which was studied, it was observed that only one third (35.4%) of them had high attitude towards selecting Public Health Dentistry as a future career, and nearly two thirds of them (58.02%) had an average attitude, with very few students having low attitude (6.48%)., Conclusion: The present study concluded that there was an average attitude of 58% among dental students, which showed that they had a considerable amount of interest in pursuing post graduation in this speciality. Efforts should be intensified, both by dental council and by the dental colleges, to develop this speciality, keeping in mind the increasing attitude of dental undergraduates towards it. This also helps in increasing the number of dental personnel who are specialized in implementation of oral health policy, which does not exist in India.

Aim: To evaluate and compare the shear bond strength of resilient liners with heat cure denture base resins in the presence or absence of saliva., Materials and Methods: Two commercially available heat polymerized acrylics and three commercially available denture liners were immersed in artificial saliva for 7 days and 14 days, respectively. A total of 180 (Acralyn-H, No.90 and Lucitone - 199, No.90) specimens were prepared. Total of 90 overlapping joint specimens were prepared, 45 of them using Acralyn H (AGroup) and rest 45 using Lucitone-199 (L-Group). The specimens were tested for flexural strength with a 3-point bending test on an Instron universal testing machine. The results were analyzed with a one-way analysis of variance (ANOVA)., Results: The mean difference in shear bond strength (SBS) at different time intervals was found to be statistically significant (p < 0.001). Lucitone-199 recorded a significantly higher mean SBS compared to Acralyn H (p < 0.001). Further, significant differences between GC and Densply, GC and Aswin liners, and between Dentsply and Aswin were noted (p < 0.001). Difference between baseline and 7 days time interval, as well as, between baseline and 14 days time interval with respect to the mean SBS of these materials were significant (p < 0.001). Also, the mean difference in SBS between 7 days time interval and 14 days time interval was statistically significant (p < 0.001). Among the three different liners, GC yielded a higher mean SBS compared to Aswin and Dentsply at all the three time intervals. The mean SBS recorded in Dentsply and Aswin was almost same at 14 days time interval, but at baseline and 7 days, it was higher in Aswin compared to Dentsply., Conclusion: Lucitone-199 recorded a higher mean SBS compared to Acralyn H. As the time interval increases, the mean SBS recorded in both the denture base materials decrease. Among the three different liners, GC yields a higher mean SBS compared to Aswin and Dentsply at all the three time intervals., Clinical Significance: The most common reason for failures of resilient linings in removable dentures is the separation of these linings from the denture base. Therefore, poor adhesive bond properties are one of the serious defects of the material in clinical practice.