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In this paper, buckling of a nanowire column subjected to self-weight and tip load is investigated. One end of the nanowire is free, while the other end is attached to a rotational spring support. Considering the equilibrium equations together with the Euler–Bernoulli beam theory, the governing differential equation describing the behavior of the column can be obtained. Effect of surface stress is also incorporated into the formulations in terms of transverse distributed loading. The differential equation has been solved analytically and the general solution can be presented in the terms of Bessel function of the first kind. Applying the boundary conditions, the characteristic equations influenced by surface stress and stiffness of the rotational spring at the support can be expressed and then the critical load can be determined using the Newton–Raphson iterative scheme. From the results, they reveal that the positive surface stress could strengthen the nanowire against the buckling. Fixity at the base is also influenced to the critical load where the increase of the stiffness of the spring results in the increase of critical load as well. [ABSTRACT FROM AUTHOR]